Cochlear Duct
A spiral tube that is firmly suspended in the bony shell-shaped part of the cochlea. This ENDOLYMPH-filled cochlear duct begins at the vestibule and makes 2.5 turns around a core of spongy bone (the modiolus) thus dividing the PERILYMPH-filled spiral canal into two channels, the SCALA VESTIBULI and the SCALA TYMPANI.
Organ of Corti
Ear, Inner
The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (COCHLEA; VESTIBULAR LABYRINTH; and SEMICIRCULAR CANALS) in the TEMPORAL BONE. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (COCHLEAR DUCT; SACCULE AND UTRICLE; and SEMICIRCULAR DUCTS) forming a continuous space enclosed by EPITHELIUM and connective tissue. These spaces are filled with LABYRINTHINE FLUIDS of various compositions.
Stria Vascularis
A layer of stratified EPITHELIUM forming the endolymphatic border of the cochlear duct at the lateral wall of the cochlea. Stria vascularis contains primarily three cell types (marginal, intermediate, and basal), and capillaries. The marginal cells directly facing the ENDOLYMPH are important in producing ion gradients and endochoclear potential.
Cochlea
Endolymphatic Duct
Hair Cells, Auditory
Sensory cells in the organ of Corti, characterized by their apical stereocilia (hair-like projections). The inner and outer hair cells, as defined by their proximity to the core of spongy bone (the modiolus), change morphologically along the COCHLEA. Towards the cochlear apex, the length of hair cell bodies and their apical STEREOCILIA increase, allowing differential responses to various frequencies of sound.
Gene Expression Regulation, Developmental
Bile Ducts
Pancreatic Ducts
Faculty, Medical
Faculty
Students, Medical
Research
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
Mechlorethamine
Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness. (1/43)
DFN3, an X chromosome-linked nonsyndromic mixed deafness, is caused by mutations in the BRN-4 gene, which encodes a POU transcription factor. Brn-4-deficient mice were created and found to exhibit profound deafness. No gross morphological changes were observed in the conductive ossicles or cochlea, although there was a dramatic reduction in endocochlear potential. Electron microscopy revealed severe ultrastructural alterations in cochlear spiral ligament fibrocytes. The findings suggest that these fibrocytes, which are mesenchymal in origin and for which a role in potassium ion homeostasis has been postulated, may play a critical role in auditory function. (+info)Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems. (2/43)
BETA2/NeuroD1 is a bHLH transcription factor that is expressed during development in the mammalian pancreas and in many locations in the central and peripheral nervous systems. During inner ear ontogenesis, it is present in both sensory ganglion neurons and sensory epithelia. Although studies have shown that BETA2/NeuroD1 is important in the development of the hippocampal dentate gyrus and the cerebellum, its functions in the peripheral nervous system and in particular in the inner ear are unclear. Mice carrying a BETA2/NeuroD1 null mutation exhibit behavioral abnormalities suggestive of an inner ear defect, including lack of responsiveness to sound, hyperactivity, head tilting, and circling. Here we show that these defects can be explained by a severe reduction of sensory neurons in the cochlear-vestibular ganglion (CVG). A developmental study of CVG formation in the null demonstrates that BETA2/NeuroD1 does not play a primary role in the proliferation of neuroblast precursors or in their decision to become neuroblasts. Instead, the reduction in CVG neuron number is caused by a combination both of delayed or defective delamination of CVG neuroblast precursors from the otic vesicle epithelium and of enhanced apoptosis both in the otic epithelium and among those neurons that do delaminate to form the CVG. There are also defects in differentiation and patterning of the cochlear duct and sensory epithelium and loss of the dorsal cochlear nucleus. BETA2/NeuroD1 is, thus, the first gene to be shown to regulate neuronal and sensory cell development in both the cochlear and vestibular systems. (+info)Spiral ligament pathology: a major aspect of age-related cochlear degeneration in C57BL/6 mice. (3/43)
Data from systematic, light microscopic examination of cochlear histopathology in an age-graded series of C57BL/6 mice (1.5-15 months) were compared with threshold elevations (measured by auditory brain stem response) to elucidate the functionally important structural changes underlying age-related hearing loss in this inbred strain. In addition to quantifying the degree and extent of hair cell and neuronal loss, all structures of the cochlear duct were qualitatively evaluated and any degenerative changes were quantified. Hair cell and neuronal loss patterns suggested two degenerative processes. In the basal half of the cochlea, inner and outer hair cell loss proceeded from base to apex with increasing age, and loss of cochlear neurons was consistent with degeneration occurring secondary to inner hair cell loss. In the apical half of the cochlea with advancing age, there was selective loss of outer hair cells which increased from the middle to the extreme apex. A similar gradient of ganglion cell loss was noted, characterized by widespread somatic aggregation and demyelination. In addition to these changes in hair cells and their innervation, there was widespread degeneration of fibrocytes in the spiral ligament, especially among the type IV cell class. The cell loss in the ligament preceded the loss of hair cells and/or neurons in both space and time suggesting that fibrocyte pathology may be a primary cause of the hearing loss and ultimate sensory cell degeneration in this mouse strain. (+info)Transcript profiling of functionally related groups of genes during conditional differentiation of a mammalian cochlear hair cell line. (4/43)
We have used Affymetrix high-density gene arrays to generate a temporal profile of gene expression during differentiation of UB/OC-1, a conditionally immortal cell line derived from the mouse cochlea. Gene expression was assessed daily for 14 days under differentiating conditions. The experiment was replicated in two separate populations of cells. Profiles for selected genes were correlated with those obtained by RT-PCR, TaqMan analysis, immunoblotting, and immunofluorescence. The results suggest that UB/OC-1 is derived from a population of nonsensory epithelial cells in the greater epithelial ridge that have the potential to differentiate into a hair-cell-like phenotype, without the intervention of Math1. Elements of the Notch signaling cascade were identified, including the receptor Notch3, with a transient up-regulation that suggests a role in hair cell differentiation. Several genes showed a profile similar to Notch3, including the transcriptional co-repressor Groucho1. UB/OC-1 also expressed Me1, a putative partner of Math1 that may confer competence to differentiate into hair cells. Cluster analysis revealed expression profiles for neural guidance genes associated with Gata3. The temporal dimension of this analysis provides a powerful tool to study genetic mechanisms that underlie the conversion of nonsensory epithelial cells into hair cells. (+info)Forced activation of Wnt signaling alters morphogenesis and sensory organ identity in the chicken inner ear. (5/43)
Components of the Wnt signaling pathway are expressed in the developing inner ear. To explore their role in ear patterning, we used retroviral gene transfer to force the expression of an activated form of beta-catenin that should constitutively activate targets of the canonical Wnt signaling pathway. At embryonic day 9 (E9) and beyond, morphological defects were apparent in the otic capsule and the membranous labyrinth, including ectopic and fused sensory patches. Most notably, the basilar papilla, an auditory organ, contained infected sensory patches with a vestibular phenotype. Vestibular identity was based on: (1) stereociliary bundle morphology; (2) spacing of hair cells and supporting cells; (3) the presence of otoliths; (4) immunolabeling indicative of vestibular supporting cells; and (5) expression of Msx1, a marker of certain vestibular sensory organs. Retrovirus-mediated misexpression of Wnt3a also gave rise to ectopic vestibular patches in the cochlear duct. In situ hybridization revealed that genes for three Frizzled receptors, c-Fz1, c-Fz7, and c-Fz10, are expressed in and adjacent to sensory primordia, while Wnt4 is expressed in adjacent, nonsensory regions of the cochlear duct. We hypothesize that Wnt/beta-catenin signaling specifies otic epithelium as macular and helps to define and maintain sensory/nonsensory boundaries in the cochlear duct. (+info)Distribution of gentamicin in the guinea pig inner ear after local or systemic application. (6/43)
Uptake and retention of gentamicin by cells in the guinea pig inner ear after a single peritoneal injection or local application on the round window were investigated using immunocytochemistry to localize the drug. The cells that accumulated the drug under the two conditions were the same, but staining for the drug was more intense and was often accompanied by widespread cochlear degeneration following local application. Soon after drug administration by either route, there was diffuse staining for the drug throughout all tissue within the labyrinth, including bone. At later times when distinct cell staining became evident, virtually all cell types were found to be positive, with several cell types staining more darkly for the drug than hair cells, indicating that hair cells were not the most avid in accumulating gentamicin. The infracuticular portion of auditory and vestibular hair cells as well as type III fibrocytes of the spiral ligament were positively stained in almost all cases and these sites were found to be positive for as long as six months post administration. In animals with loss of the organ of Corti, there was unusually intense staining for gentamicin in root cells of the spiral ligament, in marginal cells of the stria vascularis, and in cells of the spiral limbus. Dark staining of surviving cells in cases with overt tissue destruction suggests that variability in the extent of damage caused by the drug was determined more by the degree of its local uptake than by differences in animals' capacities to metabolize the drug systemically. The present results show that gentamicin may damage or destroy all cochlear cells following a single round window application. The findings broaden the scope of our knowledge of cochlear gentamicin uptake and damage and have implications for treatment of patients with vestibular disorders by infusion of aminoglycosides into the middle ear, as well as implications for prospects of rehabilitating patients that have been deafened by aminoglycosides. (+info)Changes in cytochemistry of sensory and nonsensory cells in gentamicin-treated cochleas. (7/43)
Effects of a single local dose of gentamicin upon sensory and nonsensory cells throughout the cochlea were assessed by changes in immunostaining patterns for a broad array of functionally important proteins. Cytochemical changes in hair cells, spiral ganglion cells, and cells of the stria vascularis, spiral ligament, and spiral limbus were found beginning 4 days post administration. The extent of changes in immunostaining varied with survival time and with cell type and was not always commensurate with the degree to which individual cell types accumulated gentamicin. Outer hair cells, types I and II fibrocytes of the spiral ligament, and fibrocytes in the spiral limbus showed marked decreases in immunostaining for a number of constituents. In contrast, inner hair cells, type III fibrocytes and root cells of the spiral ligament, cells of the stria vascularis, and interdental cells in the spiral limbus showed less dramatic decreases, and in some cases they showed increases in immunostaining. Results indicate that, in addition to damaging sensory cells, local application of gentamicin results in widespread and disparate disruptions of a variety of cochlear cell types. Only in the case of ganglion cells was it apparent that the changes in nonsensory cells were secondary to loss or damage of hair cells. These results indicate that malfunction of the ear following gentamicin treatment is widespread and far more complex than simple loss of sensory elements. The results have implications for efforts directed toward detecting, preventing, and treating toxic effects of aminoglycosides upon the inner ear. (+info)Synchronization of a nonlinear oscillator: processing the cf component of the echo-response signal in the cochlea of the mustached bat. (8/43)
Cochlear microphonic potential (CM) was recorded from the CF2 region and the sparsely innervated zone (the mustached bat's cochlea fovea) that is specialized for analyzing the Doppler-shifted echoes of the first-harmonic (approximately 61 kHz) of the constant-frequency component of the echolocation call. Temporal analysis of the CM, which is tuned sharply to the 61 kHz cochlear resonance, revealed that at the resonance frequency, and within 1 msec of tone onset, CM is broadly tuned with linear magnitude level functions. CM measured during the ongoing tone and in the ringing after tone offset is 50 dB more sensitive, is sharply tuned, has compressive level functions, and the phase leads onset CM by 90 degrees: an indication that cochlear responses are amplified during maximum basilar membrane velocity. For high-level tones above the resonance frequency, CM appears at tone onset and after tone offset. Measurements indicate that the two oscillators responsible for the cochlear resonance, presumably the basilar and tectorial membranes, move together in phase during the ongoing tone, thereby minimizing net shear between them and hair cell excitation. For tones within 2 kHz of the cochlear resonance the frequency of CM measured within 2 msec of tone onset is not that of the stimulus but is proportional to it. For tones just below the cochlear resonance region CM frequency is a constant amount below that of the stimulus depending on CM measurement delay from tone onset. The frequency responses of the CM recorded from the cochlear fovea can be accounted for through synchronization between the nonlinear oscillators responsible for the cochlear resonance and the stimulus tone. (+info)
Cochlear duct
The cochlear duct houses the organ of Corti. The cochlear duct is part of the cochlea. It is separated from the tympanic duct ( ... Rarely, the cochlear duct may develop to have the wrong shape. The cochlear duct is the space bounded by the scala media. ... The organ of Corti develops inside the cochlear duct. The cochlear duct contains the organ of Corti. This is attached to the ... The stria vascularis is located in the wall of the cochlear duct. The cochlear duct develops from the ventral otic vesicle ( ...
Stria vascularis of cochlear duct
The stria vascularis of the cochlear duct is a capillary loop in the upper portion of the spiral ligament (the outer wall of ... The stria vascularis is part of the lateral wall of the cochlear duct. It is a somewhat stratified epithelium containing ... the cochlear duct). It produces endolymph for the scala media in the cochlea. ... Hopkins, Kathryn (2015). "27 - Deafness in cochlear and auditory nerve disorders". Handbook of Clinical Neurology. Elsevier. pp ...
Basilar membrane
Floor of cochlear duct. Spiral limbus and basilar membrane. Section through the spiral organ of Corti (magnified) The reticular ... Fay RR, Popper AN, Bacon SP (2004). Compression: From Cochlea to Cochlear Implants. Springer. ISBN 0-387-00496-3. Oghalai JS ( ... Salt AN, Konishi T (1986). "The cochlear fluids: Perilymph and endolymph.". In Altschuler RA, Hoffman DW, Bobbin RP (eds.). ... cite journal}}: Cite journal requires ,journal= (help) Nilsen KE, Russell IJ (July 1999). "Timing of cochlear feedback: spatial ...
Otoconin
The roof of the cochlear duct also has some. By ten days after birth the protein is not found in any cells, but only in the ... In mice the protein is first formed at day 9.5 in the otic vesicle dorsal wall epithelium, and also in the endolymphatic duct. ...
Stapedectomy
Pauw BK, Pollak AM, Fisch U (December 1991). "Utricle, saccule, and cochlear duct in relation to stapedotomy. A histologic ... Poor cochlear reserve as shown by poor speech discrimination scores Patient with tinnitus and vertigo Presence of active ... Presence of Carhart's notch in the audiogram of a patient with conductive hearing loss (relative) Good cochlear reserve as ... In particular, stapedotomy procedure greatly reduces the chance of a perilymph fistula (leakage of cochlear fluid). Stapedotomy ...
Vestibular membrane
It separates the cochlear duct from the vestibular duct. It helps to transmit vibrations from fluid in the vestibular duct to ... The vestibular membrane separates the cochlear duct (scala media) from the vestibular duct (scala vestibuli). Histologically, ... The vestibular membrane helps to transmit vibrations from fluid in the vestibular duct to the cochlear duct. Together with the ... The vestibular membrane may be ruptured by an increase in the pressure of endolymph in the cochlear duct. This may occur in ...
Spiral ligament
The periosteum, forming the outer wall of the cochlear duct (Latin: ductus cochlearis), is greatly thickened and altered in ... Transverse section of the cochlear duct of a fetal cat. Diagrammatic longitudinal section of the cochlea. This article ...
Vestibular duct
It is separated from the cochlear duct by Reissner's membrane and extends from the vestibule of the ear to the helicotrema ... Transverse section of the cochlear duct of a fetal cat. Interior of right osseous labyrinth. Diagrammatic longitudinal section ... The vestibular duct or scala vestibuli is a perilymph-filled cavity inside the cochlea of the inner ear that conducts sound ... Tympanic duct Slide from University of Kansas Diagram at Indiana University - Purdue University Indianapolis Image at ...
Organ of Corti
Specifically, the cochlear duct growth and the formation of hair cells within the organ of Corti. Mutations in the genes ... Transverse section of the cochlear duct of a fetal cat. Diagrammatic longitudinal section of the cochlea Floor of ductus ... develops after the formation and growth of the cochlear duct. The inner and outer hair cells then differentiate into their ... The organ of Corti is located in the scala media of the cochlea of the inner ear between the vestibular duct and the tympanic ...
Tympanic duct
It is separated from the cochlear duct by the basilar membrane, and it extends from the round window to the helicotrema, where ... This movement is conveyed to the organ of Corti inside the cochlear duct, composed of hair cells attached to the basilar ... Transverse section of the cochlear duct of a fetal cat. The cochlea and vestibule, viewed from above. Diagrammatic longitudinal ... The purpose of the perilymph-filled tympanic duct and vestibular duct is to transduce the movement of air that causes the ...
Human embryonic development
The ventral component forms the saccule and the cochlear duct. In the sixth week of development the cochlear duct emerges and ... It remains connected to the cochlear duct via the narrow ductus reuniens. The dorsal component forms the utricle and ... Excretory tubules are formed and enter the mesonephric duct, which ends in the cloaca. The mesonephric duct atrophies in ... An outgrowth of the mesonephric duct, the ureteric bud, penetrates metanephric tissue to form the primitive renal pelvis, renal ...
Cochlear nerve
Transverse section of the cochlear duct of a fetal cat. Floor of ductus cochlearis. Diagrammatic longitudinal section of the ... the dorsal cochlear nucleus (DCN) the anteroventral cochlear nucleus (AVCN) the posteroventral cochlear nucleus (PVCN) Each of ... There, its fibers synapse with the cell bodies of the cochlear nucleus. In mammals, cochlear nerve fibers are classified as ... In mammals, the axons from each cochlear nerve terminate in the cochlear nuclear complex that is ipsilaterally located in the ...
Claudius cell
They are in direct contact with the endolymph of the cochlear duct. These cells are sealed via tight junctions that prevent ...
Basilar crest
The basilar crest lies within the cochlear duct in the inner ear. It gives attachment to the outer edge of the basilar membrane ...
Auditory system
Vestibular and tympanic ducts are filled with perilymph, and the smaller cochlear duct between them is filled with endolymph, a ... At the cochlear base the BM is at its narrowest and most stiff (high-frequencies), while at the cochlear apex it is at its ... Strikingly, one section, called the cochlear duct or scala media, contains endolymph. Endolymph is a fluid similar in ... the dorsal cochlear nucleus (DCN), and ventral cochlear nucleus (VCN). The VCN is further divided by the nerve root into the ...
Noggin (protein)
The inner ear underwent multiple deformations affecting the cochlear duct, semicircular canals, and otic capsule portions. ... related deformity due to the absence of noggin is conductive hearing loss caused by uncontrolled outgrowth of the cochlear duct ...
Ductus reuniens
It connects the lower part of the saccule to the cochlear duct near its vestibular extremity. Victor Hensen This article ...
Reticular membrane
The RM separates endolymph in the cochlear duct from underlying corticolymph and perilymph of the scala tympani. The hair ...
Ear
The cochlea consists of three fluid-filled spaces: the vestibular duct, the cochlear duct, and the tympanic duct. Hair cells ... Part of the saccule will eventually give rise and connect to the cochlear duct. This duct appears approximately during the ... membrane and the basilar membrane develop to separate the cochlear duct from the vestibular duct and the tympanic duct, ... As the cochlear duct's mesenchyme begins to differentiate, three cavities are formed: the scala vestibuli, the scala tympani ...
Inner ear
The basilar membrane separates the cochlear duct from the scala tympani, a cavity within the cochlear labyrinth. The lateral ... The hair cells develop from the lateral and medial ridges of the cochlear duct, which together with the tectorial membrane make ... Beginning in the fifth week of development, the auditory vesicle also gives rise to the cochlear duct, which contains the ... An endolymphatic duct runs from the saccule up through the head and ending close to the brain. In cartilaginous fish, this duct ...
Timurlengia
... has a long cochlear duct, with the same height as the labyrinth, an adaptation to hearing low-frequency sounds. ...
Impedance analogy
The cochlea portion of the circuit uses a finite element analysis of the continuous transmission line of the cochlear duct. An ... Fukazawa, Tatsuya; Tanaka, Yasuo, "Evoked otoacoustic emissions in a cochlear model", pp. 191-196 in Hohmann, D. (ed), ECoG, ...
Cochlea
The cochlear duct is almost as complex on its own as the ear itself. The cochlear duct is bounded on three sides by the basilar ... The perilymph in the vestibular duct and the endolymph in the cochlear duct act mechanically as a single duct, being kept apart ... which lies inferior to the cochlear duct and terminates at the round window the cochlear duct or scala media (containing ... separates the cochlear duct from the tympanic duct and determines the mechanical wave propagation properties of the cochlear ...
Neural encoding of sound
The fluid found in these two cochlear chambers is perilymph, while scala media, or the cochlear duct, is filled with endolymph ... Cochlear hair cells are organized as inner hair cells and outer hair cells; inner and outer refer to relative position from the ... The apical surface of each cochlear hair cell contains a hair bundle. Each hair bundle contains approximately 300 fine ... Encoding shifts from synchronous responses in the cochlear nucleus and later becomes dependent on rate encoding in the inferior ...
Sound localization in owls
The cochlear duct of the owl contains the basilar papilla, the tectorial membrane, the tegmentum vasculum, and the macula of ... the cochlear nucleus magnocellularis (mammalian anteroventral cochlear nucleus) and the cochlear nucleus angularis (see figure ... The fibers of the auditory nerve innervate both cochlear nuclei in the brainstem, ... mammalian posteroventral and dorsal cochlear nuclei). The neurons of the nucleus magnocellularis phase-lock, but are fairly ...
Crista ampullaris
The semicircular canals are filled with endolymph due to its connection with the cochlear duct via the saccule, which also ... as well as the cochlear duct, which is involved in the special sense of hearing. ... The receptor cells located in the semicircular ducts are innervated by the eighth cranial nerve, the vestibulocochlear nerve ( ... Upon angular acceleration (rotation), the endolymph within the semicircular duct deflects the cupula against the hair cells of ...
Otic vesicle
... end of the otic vesicle gradually elongates as a tube and coils upon itself forming the beginnings of the cochlear duct. The ...
Bissektipelta
The elongated cochlear ducts in the more advanced ankylosaurines seem to indicate that these traits were adapted for enhanced ... In addition, the length of the cochlear ducts in the inner ear suggests that Bissektipelta, and many other ankylosaurs, were ...
Barakat syndrome
... the failure in the specification of prosensory domain and subsequently leads to increased cell death in the cochlear duct thus ...
Surface wave
... resulted from an acoustic surface wave of the basilar membrane into the cochlear duct. His theory purported to explain every ...
Index of anatomy articles
... claustrum clava clavicle climbing fiber clinoid clitoris clivus cloaca clonus coccyx cochlea cochlear duct cochlear nerve ... Edinger-Westphal nucleus efferent ducts efferent nerve fiber efferent limb ejaculatory duct elbow electrical conduction system ... sinus sphenopalatine artery sphenopalatine foramen sphincter sphincter of the bile duct sphincter of the pancreatic duct ... frontal horn of lateral ventricle frontal lobe frontal nerve frontal plane frontal pole frontal sinus frontonasal duct ...
Claude-Henri Chouard
... placed in different locations within the tympanic duct of the cochlear, resulted in the perception of different frequencies. ... "History of the french cochlear implant". Chouard, CH (Dec 2014). "Technical survey of the French role in multichannel cochlear ... the cochlear implant would need several electrodes, so it could stimulate the different frequency regions on the "cochlear ... The multichannel cochlear implant was designed and developed in 1975 at Saint-Antoine Hospital by a multidisciplinary team ...
Hair cell
... tufts of stereocilia called hair bundles that protrude from the apical surface of the cell into the fluid-filled cochlear duct ... Mammalian cochlear hair cells are of two anatomically and functionally distinct types, known as outer, and inner hair cells. ... Slow adaptation is most prominent in vestibular hair cells that sense spatial movement and less in cochlear hair cells that ... Research on the regrowth of cochlear cells may lead to medical treatments that restore hearing. Unlike birds and fish, humans ...
Stereocilia (inner ear)
Unlike the semicircular ducts, the kinocilia of hair cells in the otoliths are not oriented in a consistent direction. The ... This, in turn, causes receptor depolarization and leads to the excitement of the cochlear nerve afferents that are located at ... Bosher, S. K.; Warren, R. L. (1978). "Very low calcium content of cochlear endolymph, an extracellular fluid". Nature. 273 ( ... Jia, Shuping (2009). "Fate of mammalian cochlear hair cells and stereocilia after loss of the stereocilia". Journal of ...
Cilium
Wang, D; Zhou, J (2021). "The Kinocilia of Cochlear Hair Cells: Structures, Functions, and Diseases". Frontiers in Cell and ... Primary cilia are present in exocrine cells which are centroacinar, duct cells. Endocrine tissue is composed of different ...
Emil Huschke
Tooth-shaped ridges occurring on the vestibular lip of the limbus lamina spiralis of the cochlear duct. Huschke's cartilages: ...
Pendrin
Kim HM, Wangemann P (November 2010). "Failure of fluid absorption in the endolymphatic sac initiates cochlear enlargement that ... and has been localized to the apical membrane of a population of intercalated cells in the cortical collecting duct where it is ... "Loss of cochlear HCO3- secretion causes deafness via endolymphatic acidification and inhibition of Ca2+ reabsorption in a ...
Human brain
A single duct, the cerebral aqueduct between the pons and the cerebellum, connects the third ventricle to the fourth ventricle ... From here, it passes through to the cochlear nuclei, the superior olivary nucleus, the medial geniculate nucleus, and finally ...
Glossary of medicine
It receives and stores bile, produced by the liver, via the common hepatic duct and releases it via the common bile duct into ... hearing ability is mediated by the inner ear composed of the cochlea with its internal basilar membrane and attached cochlear ... which joins with the cystic duct (carrying bile to and from the gallbladder) to form the common bile duct, which opens into the ... these ducts transport sperm from the epididymis to the ejaculatory ducts in anticipation of ejaculation. It is a partially ...
Outline of human anatomy
... labyrinth Utricle Saccule Semicircular ducts Utriculosaccular duct Endolymphatic duct Cochlear labyrinth Cochlear duct Spiral ... Descending colon Sigmoid colon Rectum Anal canal Pectinate line Liver Common hepatic duct Gall bladder Cystic duct Bile duct ... vein Inferior mesenteric vein Left colic vein Sigmoid veins Superior rectal vein Lymphatic trunks and ducts Thoracic duct ... Skin glands Sweat gland Sebaceous gland Nail Lunule Breast Nipple Mammary gland Lactiferous duct Lactiferous sinus Areola ...
Saccule
... endolymphatic duct). This duct is joined by the ductus utriculosaccularis, and then passes along the aquæductus vestibuli and ... Jeremy Cochlear neurosensory specification and competence University of Iowa, 2012 (Articles with short description, Short ... It is globular in form and lies in the recessus sphæricus near the opening of the vestibular duct of the cochlea. Its cavity ... The vestibule is the name of the fluid-filled, membranous duct that contains these organs of balance. The vestibule is encased ...
Magnetic resonance imaging
Hepatobiliary MR is used to detect and characterize lesions of the liver, pancreas, and bile ducts. Focal or diffuse disorders ... Contraindications to MRI include most cochlear implants and cardiac pacemakers, shrapnel, and metallic foreign bodies in the ... Anatomical imaging of the bile ducts is achieved by using a heavily T2-weighted sequence in magnetic resonance ...
Stimulus (physiology)
Hair cells in the cochlear duct, specifically the organ of Corti, are deflected as waves of fluid and membrane motion travel ... Semi circular ducts, which are connected directly to the cochlea, can interpret and convey to the brain information about ... Hair cells in these parts of the ear protrude kinocilia and stereocilia into a gelatinous material that lines the ducts of this ... Neurons of the adjacent vestibular ganglia monitor the hair cells in these ducts. These sensory fibers form the vestibular ...
Irritator
They also noted that the relatively well-developed cochlear duct may have enable an average hearing frequency of 1950 Hz with a ...
PTPRU
... and the cochlear ducts of the inner ear. PCP-2 expression in most of these tissue changes over the course of development. PCP-2 ...
Kinocilium
Unlike the hair cells of the crista ampullaris or the maculae of the saccule and utricle, hair cells of the cochlear duct do ... Kinocilia are present in the crista ampullaris of the semicircular ducts and the sensory maculae of the utricle and saccule. ...
List of MeSH codes (A09)
... cochlear aqueduct MeSH A09.246.631.246.292 - cochlear duct MeSH A09.246.631.246.292.876 - stria vascularis MeSH A09.246.631.246 ... endolymphatic duct MeSH A09.246.631.909.957.360.701 - endolymphatic sac MeSH A09.371.060.067 - anterior chamber MeSH A09.371. ... nasolacrimal duct MeSH A09.371.509.155 - lens capsule, crystalline MeSH A09.371.509.225 - lens cortex, crystalline MeSH A09.371 ...
Myosin II regulates extension, growth and patterning in the mammalian cochlear duct - PubMed
... cochlea comprises mechanosensory hair cells that are arranged into four ordered rows extending along the length of the cochlear ... Myosin II regulates extension, growth and patterning in the mammalian cochlear duct Norio Yamamoto 1 , Takayuki Okano, Xuefei ... Myosin II regulates extension, growth and patterning in the mammalian cochlear duct Norio Yamamoto et al. Development. 2009 Jun ... D,E) Phalloidin labeling (green) of cell-cell boundaries in the cochlear duct. The prosensory domain is illustrated in violet. ...
Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors | Nature Communications
Hearing requires mechanosensitive hair cells in the organ of Corti, which derive from progenitors of the cochlear duct. Here ... when cochlear hair cells become specified. Utilizing surface markers for the cochlear prosensory domain, namely EPCAM and CD271 ... human inner ear development by studying key developmental markers and describe organoid cultures from human cochlear duct ... Sensory hair cells located in the organ of Corti are essential for cochlear mechanosensation. Their loss is irreversible in ...
Section on Developmental Neuroscience | NIDCD
Cross sections through the cochlear duct illustrating expression of the transcription factor Atoh1 in red and the motor protein ... Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development. Jun;136(12):1977-86, 2009. ... Transfection of mouse cochlear explants by electroporation. Curr Protoc Neurosci. Apr;Chapter 4:Unit 4.34.1-10, 2010. ... Rüsch A, Ng L, Goodyear R, Oliver D, Lisoukov I, Vennström B, Richardson G, Kelley MW, Forrest D. Retardation of cochlear ...
Mapping and characterization of a novel cochlear gene in human and in mouse: a positional candidate gene for a deafness...
Previously we identified a partial human cDNA for a novel cochlear transcript, hCoch-5B2 (HGMW-approved symbol D14S564E), using ... Cochlear Duct / metabolism Actions. * Search in PubMed * Search in MeSH * Add to Search ... Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction. Robertson NG, Lu L, ... Mapping and characterization of a novel cochlear gene in human and in mouse: a positional candidate gene for a deafness ...
Biomarkers Search
Determination of Cochlear Duct Length With 3D. Waldeck S; VON Falck C; Chapot R; Brockmann M; Overhoff D. In Vivo; 2021; 35(6): ... 6. Imaging cochlear implantation with round window insertion in human temporal bones and cochlear morphological variation using ... 8. Cone-beam CT versus multi-slice CT systems for postoperative imaging of cochlear implantation--a phantom study on image ...
Hearing Impairment: Practice Essentials, Anatomy, Pathophysiology
Along one of the membranes in the scala media, or cochlear duct, lie the internal and external hair cells. Movement of the ... especially if the otolaryngologist is part of a cochlear implant program. In addition to the surgeon, most cochlear implant ... Cochlear malformations. Neural foramen on the right is absent. Right arrow indicates a rudimentary vestibule. On the left is a ... Cochlear transduction and the molecular basis of auditory pathology. Flint PW, Francis HW, Haughey BH, Lesperance MM, Lund VJ, ...
MeSH Browser
Cochlear Duct Preferred Term Term UI T008839. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1975). ... Cochlear Duct [A09.246.300.246.292] * Stria Vascularis [A09.246.300.246.292.876] * Tectorial Membrane [A09.246.300.246.292.938] ... Cochlear Duct Preferred Concept UI. M0004684. Scope Note. A spiral tube that is firmly suspended in the bony shell-shaped part ... This ENDOLYMPH-filled cochlear duct begins at the vestibule and makes 2.5 turns around a core of spongy bone (the modiolus) ...
NIOSHTIC-2 Search Results - Full View
Portions of the cochlear duct can be dissected free from the otic capsule, placed flat on microscope slides in a liquid medium ... The dissected segments of the cochlear duct were re-embedded in thin layers of plastic for examination by phase-contrast ... The thick and semi-thick sections of inner ear and organ of Corti and flat preparations of the cochlear duct were photographed ... The cochlea can also be embedded in plastic before dissection of the cochlear duct (Bohne and Harding, 1997). The various cells ...
TREE NUMBER DESCRIPTOR
Cochlear Aqueduct A09.246.300.246.292 Cochlear Duct A09.246.300.246.292.876 Stria Vascularis A09.246.300.246.292.938 Tectorial ... Bile Ducts A03.159.183.079 Bile Ducts, Extrahepatic A03.159.183.079.300 Common Bile Duct A03.159.183.079.300.950 Ampulla of ... Vitelline Duct A16.935 Wolffian Ducts A16.950 Zygote A17 Integumentary System A17.100 Animal Scales A17.360 Hair A17.360.148 ... Hepatic Duct, Common A03.159.183.158 Bile Ducts, Intrahepatic A03.159.183.158.125 Bile Canaliculi A03.159.439 Gallbladder ...
The dark kinase STK32A regulates hair cell planar polarity opposite of EMX2 in the developing mouse inner ear | eLife
... and injected at 2 µg/µl into the cochlear duct using the Wiretroll plunger system (53507-426, Drummond). Next, the whole inner ... Inner ear electroporation and cochlear culture. Request a detailed protocol Inner ears from wild-type animals (C57BL/6J x FVB/ ... To quantify GPR156 in cochlear explants, we defined a 2x0.5 µm window in Fiji and positioned it on an medial or lateral outer ... A second function is revealed by the ectopic overexpression of STK32A in cochlear hair cells where the apical distribution of ...
DeCS
Cochlear Duct Entry term(s). Cochlear Ducts Cochlearis, Ductus Duct, Cochlear Ducts, Cochlear Ductus Cochlearis Media, Scala ... Cochlear Ducts. Cochlearis, Ductus. Duct, Cochlear. Ducts, Cochlear. Ductus Cochlearis. Media, Scala. Medias, Scala. Scala ... Cochlear Duct - Preferred Concept UI. M0004684. Scope note. A spiral tube that is firmly suspended in the bony shell-shaped ... This ENDOLYMPH-filled cochlear duct begins at the vestibule and makes 2.5 turns around a core of spongy bone (the modiolus) ...
MeSH Browser
Cochlear Duct Preferred Term Term UI T008839. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1975). ... Cochlear Duct [A09.246.300.246.292] * Stria Vascularis [A09.246.300.246.292.876] * Tectorial Membrane [A09.246.300.246.292.938] ... Cochlear Duct Preferred Concept UI. M0004684. Scope Note. A spiral tube that is firmly suspended in the bony shell-shaped part ... This ENDOLYMPH-filled cochlear duct begins at the vestibule and makes 2.5 turns around a core of spongy bone (the modiolus) ...
Cochlea 4 | Digital Histology
Cochlear duct The cochlear duct, part of the membranous labyrinth, is a triangular-shaped wedge located in the cochlea. The ... Cochlear duct. The cochlear duct, part of the membranous labyrinth, is a triangular-shaped wedge located in the cochlea. The ... The cochlear duct, part of the membranous labyrinth, is a triangular-shaped wedge located in the cochlea. The cochlear duct, ... The cochlear duct, part of the membranous labyrinth, is a triangular-shaped wedge located in the cochlea. The cochlear duct, ...
Anthony J. Ricci, PhD's Profile | Stanford Profiles
3D image stacks of the organ of Corti were obtained from base to apex in the cochlear duct, from which 3D lengths and relative ... The variations of this Y-shaped element along the cochlear duct and between the rows of outer hair cells are shown with the ... Here, we use cochlear hair cell ablation to isolate the effects of SNHL. Cochlear hair cells were conditionally and selectively ... Effects of cochlear hair cell ablation on spatial learning/memory. Scientific reports Qian, Z. J., Ricci, A. J. 2020; 10 (1): ...
Ontogenetic braincase development in Psittacosaurus lujiatunensis (Dinosauria: Ceratopsia) using micro-computed tomography ...
Pesquisa | Portal Regional da BVS
The cochlear duct initiates rotation at late stage 19. The cochlear duct continues to rotate and forms approximately one ... The cochlear duct already begins to extend at stage 16. First it extends to the opposite direction of the future cochlear ... The lateral semicircular duct is formed similarly at stages 18 and 19. In the mesenchyme of the lateral semicircular duct, we ... The endolymphatic duct begins to extend at stage 18 and continues to extend. The formation of the anterior and posterior ...
Characterization of the development of the mouse cochlear epithelium at the single cell level - PubMed
e Upper left panel, tSNE plot of cells determined to be derived from KO (between the OC and medial edge of the cochlear duct). ... a Line drawing of a cross section of the floor of the cochlear duct at P1. Distinct cell types within the organ of Corti (OC) ... Lower right panel, cross sections through the cochlear duct at P1, illustrating expression of CALB1 in the medial region of KO ... To examine cochlear development more closely, we transcriptionally profile approximately 30,000 isolated mouse cochlear cells ...
Threesology Research Journal
Special sense of hearing
COCHLEA AND COCHLEAR DUCT Cochlea means snail In the center is a cone-shaped core termed modiolus The modiolus houses the ... Cochlear ducts are the only part of the internal ear concerned with hearing ... Depolarization of hair cells transmits impulse along the cochlear branch of the vestibulo-cochlear sensory nerve ... Deafness Tinnitus- ringing or clicking sound in the absence of auditory stimuli 1st symptom of cochlear nerve degeneration ...
Ear: Useful Notes on Human Ear (13270 Words)
Cochlear duct (Scala media):. The duct lies along the outer wall of the bony cochlear canal and undergoes a spiral course of ... Semicircular ducts:. The three semicircular ducts are contained within the corresponding bony canals. Each duct passes along ... where it joins with the saccule by a narrow duct, the ductus reuniens. The cochlear duct contains the spiral organ of Corti ( ... a) Cochlear duct (scala media) within the bony cochlea; it contains the spiral organ of Corti which acts as peripheral organ of ...
Otolaryngology | Head and Neck Surgery | At UCSF
The Sound and Music Perception Lab at UCSF is devoted to exploring music perception and complex sound processing in cochlear ... Computed Tomography-Based Measurements of the Cochlear Duct: Implications for Cochlear Implant Pitch Tuning. Ear Hear 42(3):732 ... One area of research centers around music perception in cochlear implant users; cochlear implants are surgical devices that ... cochlear implant users. We will conduct a Zoom interview for 45 minutes and discuss the cochlear implant users music listening ...
Cochise College: Tabular Data | Encyclopedia.com
Facts About (Eye) Iris Color - Board Certified Eye Doctors | Burlington Bucks County Millville
NEW (2009) MESH HEADINGS WITH SCOPE NOTES (UNIT RECORD FORMAT; 10/20/2008
A spiral thickening of the fibrous lining of the cochlear wall. Spiral ligament secures the membranous COCHLEAR DUCT to the ... Terminal bronchioles lead into several orders of respiratory bronchioles which in turn lead into alveolar ducts and then into ... Its spiral ligament fibrocytes function in conjunction with the STRIA VASCULARIS to mediate cochlear ion homeostasis. HN - 2009 ...
October - January 2014: Also 2nd- and 3rd-order intervals of spontaneous otoacoustic emissions confirm theory of local tuned...
... traveling waves between the stapes and points of slight functional irregularities along the cochlear duct, in analogy with the ... Kemp DT (1979) The evoked cochlear mechanical response and the auditory microstructure - Evidence for a new element in cochlear ... The standing wave is sustained by energy input from elements of the cochlear amplifier, in particular the outer hair cells (OHC ... 1996), proposes that the same elements of the cochlear amplifier behave as local oscillators without being coupled to a ...
JBC Man of the Year & Young Men
Morphology And Anatomy Of Frog
Lagena is the forerunner of the cochlear duct of higher vertebrates.. Pars basilaris seems to be a part of lagena. A small ... The cystic duct proceeds towards the duodenum as the bile duct. When the bile duct passes through pancreas, it receives some ... The gall bladder gives rise to a duct, the cystic duct, which also receives a few hepatic ducts from the liver directly. ... Ureters Urinogenital ducts. From the outer border of each kidney a fine trans-parent duct arises, which is known as ureter in ...
The Ear | Veterian Key
20-6) is sometimes blurred in textbooks by the carefree use of canal for duct and cochlea for cochlear duct. To understand the ... Cochlear Duct-Spiral Organ. The most highly developed and differentiated portion of the membranous labyrinth is the cochlear ... A thin vestibular membrane forms the roof of the cochlear duct and a thicker basilar membrane forms the floor of the duct. The ... A secondary tympanic membrane closes this cochlear window. The membranous cochlear duct, formerly scala media, completes the ...
Inner Ear - Structure of The Ear
The unit-ing duct (AB13) forms a connection betweenthe saccule and the membranous cochlear duct.. ... The spiral canal of thecochlea (C14) contains the membranous cochlear duct (AB15) which starts with ablind end, the vestibular ... The three semicircular ducts are arranged perpendicularly to each other. The convexity of the anterior semi-circular duct (B23 ... The anterior and posterior semicircular ducts diverge from the median and frontal planes by 45!; the lateral semicircular duct ...
Cochlear section
It contains the cochlear duct, part of the Feb 5, 2020 We performed single-cell RNA-Seq on FACS-purified adult cochlear in situ ... The perilymph fluid in the canals differs from the endolymph fluid in the cochlear duct. The organ specific surgery. ... And always As the global leader in implantable hearing solutions, Welcome to Cochlear Nordic Education and Events. Cochlear ... and the cochlear duct.. bio 142 cochlea model, lab packet i (pg. #12)narrator: tanyathank you belinda..use this as a ...
Wall of the cochlear ductCOCHLEA AND COCHLEAREndolymphImplantOrganProsensory domainVestibularSemicircular ductsEpitheliumScala tympaniPetrous boneMembranousBile ductImplantationDilatationMicroscopicPosteriorStapes2020NerveCanalsMembranesBasilarFrequencyOuterHairProcessesHumanDevelopmentLengthIncludeSectionImageGlobal
Wall of the cochlear duct2
- The stria vascularis, an epithelium located on the outer wall of the cochlear duct, is unique in that it is the only vascularized epithelium in mammals. (digitalhistology.org)
- The endolymph contained within the membranous labyrinth is thought to be derived from the blood vessels and epithelium of the stria vascularis along the peripheral wall of the cochlear duct and is absorbed back into the blood through the blood vessels surrounding the endolymphatic sac. (veteriankey.com)
COCHLEA AND COCHLEAR1
- Schematic transection of a cochlea and cochlear duct. (veteriankey.com)
Endolymph4
- This ENDOLYMPH-filled cochlear duct begins at the vestibule and makes 2.5 turns around a core of spongy bone (the modiolus) thus dividing the PERILYMPH-filled spiral canal into two channels, the SCALA VESTIBULI and the SCALA TYMPANI . (nih.gov)
- The cochlear duct, filled with endolymph, lies in the middle of the cochlea, dividing it into thirds, with the scala vestibuli above and the scala tympani below the cochlear duct. (digitalhistology.org)
- The scala vestibuli and scala tympani are filled with perilymph, and the cochlear duct with endolymph. (veteriankey.com)
- The perilymph fluid in the canals differs from the endolymph fluid in the cochlear duct. (web.app)
Implant10
- In many instances, the otolaryngologist develops a long-term relationship with patients and their families, caring for the patients through their spectrum of development, especially if the otolaryngologist is part of a cochlear implant program. (medscape.com)
- The Sound and Music Perception Lab at UCSF is devoted to exploring music perception and complex sound processing in cochlear implant users as well as the neural substrates of musical creativity. (ucsf.edu)
- We seek to understand how culture influences music listening and rehabilitation of adult Asian American Pacific Islander (AAPI) cochlear implant users. (ucsf.edu)
- We will conduct a Zoom interview for 45 minutes and discuss the cochlear implant user's music listening frequency, preferences, and role of culture on music listening. (ucsf.edu)
- Cochlear implant devices are available in single-channel and multi-channel models. (web.app)
- Above all else, the purpose of a cochlear implant is to create the best possible communication between the electrode array and the delicate neural structures of cochlea. (medel.pro)
- How do we provide the most natural hearing possible with a cochlear implant? (medel.pro)
- Finally, our unique variable-rate FineHearing sound coding is the only sound coding that uses two types of sound coding to mimic both tonotopic stimulation and temporal phase-locking in natural hearing for a sound quality that no other cochlear implant can match. (medel.pro)
- For more than 25 years, we've worked to create the most atraumatic cochlear implant electrode arrays possible. (medel.pro)
- Our free-fitting arrays are uniquely engineered to deliver unparalleled flexibility , making them the most atraumatic cochlear implant electrode arrays available. (medel.pro)
Organ5
- Sensory hair cells located in the organ of Corti are essential for cochlear mechanosensation. (nature.com)
- Hair cells and supporting cells within the organ of Corti are arranged in precise rows that extend along the entire length of the cochlear spiral. (nih.gov)
- The organ of Corti, the receptor for sound, is housed in the cochlear duct. (digitalhistology.org)
- Within the cochlear duct is the organ that converts mechanical vibrations to electrical action potentials. (byui.edu)
- Cochlear labyrinth Synonyms: Scala media, Cochlear labyrinth The organ of hearing spiral organ is presented within the cochlear duct. (vumc.org)
Prosensory domain3
- Convergence and extension of the cochlear prosensory domain. (nih.gov)
- Utilizing surface markers for the cochlear prosensory domain, namely EPCAM and CD271, we purify postmitotic hair cell progenitors that, when placed in culture in three-dimensional organoids, regain proliferative potential and eventually differentiate to hair cell-like cells in vitro. (nature.com)
- Hair cells and their surrounding non-sensory supporting cells derive from SOX2+ progenitors within a region of the developing cochlear duct known as the prosensory domain (PSD) 1 . (nature.com)
Vestibular7
- The overall goals of the Section on Developmental Neuroscience (Laboratory of Cochlear Development) are to identify the molecular and cellular factors that play a role in the development of the different structures within the cochlea and inner ear, including the auditory and vestibular sensory epithelia and the spiral ganglion, which acts as the first relay between the inner ear and the brain. (nih.gov)
- Este conducto rrelleno de ENDOLINFA comienza en el vestíbulo y realiza 2,5 vueltas alrededor de un centro de hueso esponjoso (el modiolo) dividiendo así el canal espiral óseo relleno de PERILINFA en dos canales, la RAMPA VESTIBULAR y la RAMPA TIMPÁNICA. (bvsalud.org)
- The internal ear is concerned with the conversion of sound energy into nerve energy and conveys the sense of hearing and equilibration by the cochlear and vestibular division of the 8th cranial nerve. (yourarticlelibrary.com)
- In the vestibule are two openings: the more dorsal vestibular window in which is inserted the foot plate of the stapes and the more ventrorostral cochlear window , which is closed by a membrane and is located at the end of the cochlea where perilymph vibrations can be dampened into the tympanic cavity. (veteriankey.com)
- The endolymphatic duct is an extension from the utriculosaccular duct through the bony vestibular aqueduct to the intracranial dura where the duct expands into a endolymphatic sac . (veteriankey.com)
- The spiral canal of thecochlea ( C14 ) contains the membranous cochlear duct ( AB15 ) which starts with ablind end, the vestibular cecum ( B16 ), and ends in the tip of the cochlea, or cupula ( C17 ), with the cupular cecum ( B18 ). (brainkart.com)
- The labyrinthine artery divides into: cochlear artery, for irrigation of the cochlea and vestibular arteries anterior and posterior semicircular canals to irrigate, utricle, saccule and part of the cochlea 8 . (bvsalud.org)
Semicircular ducts6
- These compartments are contained within the components of the bony labyrinth and include the saccule and utriculus within the bony vestibule connected by the utriculosaccular duct , the three semicircular ducts within the bony semicircular canals that connect to the utriculus and a cochlear duct within the bony cochlea that is connected to the saccule by the ductus reuniens . (veteriankey.com)
- The three semicircular ducts are the anterior (vertical), posterior (vertical), and lateral (horizontal). (veteriankey.com)
- The three bony semicircular canals ( C5 ) emanating from the vestibule contain the membranous semicircular ducts ( A22 ), which are connected to the utricle. (brainkart.com)
- The three semicircular ducts are arranged perpendicularly to each other. (brainkart.com)
- The ante-rior and the posterior semicircular ducts join to form the common membranous crus ( AB27 ). (brainkart.com)
- The courses taken by the semicircular ducts do not correspond to the axes of the body. (brainkart.com)
Epithelium3
- The sensory epithelium of the mammalian cochlea comprises mechanosensory hair cells that are arranged into four ordered rows extending along the length of the cochlear spiral. (nih.gov)
- These results identify the first molecule, myosin II, which directly regulates cellular patterning and alignment within the cochlear sensory epithelium. (nih.gov)
- Both structures contain sensory epithelium in a circumscribed part of the wall (blue), the macula of the saccule ( AB8 ) and the mac-ula of the utricle ( AB9 ), and are intercon-nected by the utriculosaccular duct ( AB10 ). (brainkart.com)
Scala tympani3
- One source is CSF from the subarachnoid space that gains entrance to the scala tympani of the cochlea via the perilymphatic duct ( ductus perilymphaticus ) (not part of the membranous labyrinth) in the small cochlear canaliculus ( canaliculus cochleae ). (veteriankey.com)
- A cross section through one of the turns of the cochlea (inset) showing the scala tympani and scala vestibuli, which contain perilymph, and the cochlear duct, … However, this is only a simplified depiction of the cochlea, often used to focus on the interaction between the fluid and basilar membrane motion. (web.app)
- Download this stock image: A cross section through one of the turns of the cochlea showing the scala tympani and scala vestibuli, and the cochlear duct. (web.app)
Petrous bone2
- The latter gives off the slender endolym-phatic duct ( A11 ) which runs to the poste-rior surface of the petrous bone and ends beneath the dura mater as a flattened ves-icle, the endolymphatic sac ( A12 ). (brainkart.com)
- The convexity of the anterior semi-circular duct ( B23 ) is oriented toward thesurface of the petrous pyramid, the posteriorsemicircular duct ( B24 ) runs parallel to theposterior surface of the petrous bone, and the lateral semicircular duct ( B25 ) runs hori-zontally. (brainkart.com)
Membranous4
- The cochlear duct, part of the membranous labyrinth, is a triangular-shaped wedge located in the cochlea. (digitalhistology.org)
- The membranous cochlear duct, formerly scala media, completes the separation of the two scalae. (veteriankey.com)
- The unit-ing duct ( AB13 ) forms a connection betweenthe saccule and the membranous cochlear duct. (brainkart.com)
- It lies within the petrous portion of the temporal bone and consists of bags and ducts of the membranous labyrinth. (bvsalud.org)
Bile duct3
- Pancreatic enzyme elevations suggest that bile duct stones caused the cholangitis, with or without gallstone pancreatitis. (medscape.com)
- [ 14 ] It is highly sensitive and specific for examining the gallbladder and assessing bile duct dilatation (see the following image). (medscape.com)
- However, it often misses stones in the distal bile duct. (medscape.com)
Implantation3
- 6. Imaging cochlear implantation with round window insertion in human temporal bones and cochlear morphological variation using high-resolution cone beam CT. (nih.gov)
- 8. Cone-beam CT versus multi-slice CT systems for postoperative imaging of cochlear implantation--a phantom study on image quality and radiation exposure using human temporal bones. (nih.gov)
- till primära hörselbarken och innehåller till exempel Wernickes area, Complications of Cochlear Implantation in Adults. (web.app)
Dilatation1
- Each semicircular duct has a dilatation at its transition to the utricle, the membranousampulla ( B26 ), which corresponds to an os-seous ampulla in the bony canal. (brainkart.com)
Microscopic2
- The microscopic nerves culminate in the cochlear portion of the eighth cranial nerve. (medscape.com)
- Because of its small size, the mouse cochlea presents some advantages and disadvantages for cochlear preparation and microscopic evaluation. (cdc.gov)
Posterior1
- The perilymphatic space communicates with the subarachnoid space via the perilym-phatic duct ( A1 ) at the posterior edge of thepetrous bone. (brainkart.com)
Stapes1
- The GST, based on concepts of Kemp (1979) , Zweig and Shera (1995) , and Shera (2003) , proposes coherent reflections of basilar membrane (BM) traveling waves between the stapes and points of slight functional irregularities along the cochlear duct, in analogy with the coherent wave reflections in the optical cavity of a laser. (oae.it)
20201
- It contains the cochlear duct, part of the Feb 5, 2020 We performed single-cell RNA-Seq on FACS-purified adult cochlear in situ hybridization co-localization in adult cochlear cross-sections and Jan 11, 2012 For serial-section material, 3-D reconstructions of the cochlear spiral were made using computer-aided anatomy software (Neurolucida), after An electrical signal stimulates the hearing nerve directly, bypassing the damaged part of the ear. (web.app)
Nerve3
- Note the hair cells and cochlear nerve. (slideshare.net)
- the cochlea or cochlear nerve can frequently be success- fully treatedby cochlearnerve section. (web.app)
- Intractable subjective tinnitus originat- ing within the cochlea or cochlear nerve canfr equently be successfully treated by cochlear nerve section. (web.app)
Canals1
- The cochlear duct is isolated from the two canals by membranes. (jerusalemmbc.net)
Membranes1
- Along one of the membranes in the scala media, or cochlear duct, lie the internal and external hair cells. (medscape.com)
Basilar1
- use this as a referenceyour dedication and hours upon hours of studyin Cochlear implants bypass the eardrum, the ossicular chain, the basilar membrane, and the (usually dead) hair cells. (web.app)
Frequency1
- 1996) used a mathematical cochlear model to test the effect of frequency distance on mutual interaction of SOAEs. (oae.it)
Outer2
- In conclusion, also 2nd- and 3rd-order spacing of SOAEs is consistent with the local oscillator theory of SOAE generation, and thus with intrinsic tuning of cochlear outer hair cells. (oae.it)
- The standing wave is sustained by energy input from elements of the cochlear amplifier, in particular the outer hair cells (OHC). (oae.it)
Hair1
- The first appearance of hair cells within the human cochlear duct has previously been reported during the 12-13th week of development 12 . (nature.com)
Processes1
- Central processes of these neurons form the cochlear division of CN VIII. (digitalhistology.org)
Human1
- Previously we identified a partial human cDNA for a novel cochlear transcript, hCoch-5B2 (HGMW-approved symbol D14S564E), using subtractive hybridization techniques. (nih.gov)
Development1
- Cover image illustrating changes in the distribution of Sox2-positive cells during cochlear development. (nih.gov)
Length2
Include1
- Disadvantages to sonography include operator and patient dependence, cannot image the cystic duct, and decreased sensitivity for distal CBD stones. (medscape.com)
Section1
- This chapter describes the industriell expansion i Göteborgsområdet med företagen Cochlear, Oticon Medical och Vi pratar med Florian Gilcher på Critical Section. (web.app)
Image1
- Ultrasonography can differentiate intrahepatic obstruction from extrahepatic obstruction and image dilated ducts. (medscape.com)
Global1
- And always As the global leader in implantable hearing solutions, Welcome to Cochlear Nordic Education and Events. (web.app)
