Cochlear Diseases: Pathological processes of the snail-like structure (COCHLEA) of the inner ear (LABYRINTH) which can involve its nervous tissue, blood vessels, or fluid (ENDOLYMPH).Pragmatic Clinical Trials as Topic: Works about randomized clinical trials that compare interventions in clinical settings and which look at a range of effectiveness outcomes and impacts.Genome: The genetic complement of an organism, including all of its GENES, as represented in its DNA, or in some cases, its RNA.Genome, Bacterial: The genetic complement of a BACTERIA as represented in its DNA.Genome, Viral: The complete genetic complement contained in a DNA or RNA molecule in a virus.Genome, Plant: The genetic complement of a plant (PLANTS) as represented in its DNA.Genome, Human: The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Protein Modification, Translational: Any of the enzymatically catalyzed modifications of the individual AMINO ACIDS of PROTEINS, and enzymatic cleavage or crosslinking of peptide chains that occur pre-translationally (on the amino acid component of AMINO ACYL TRNA), co-translationally (during the process of GENETIC TRANSLATION), or after translation is completed (POST-TRANSLATIONAL PROTEIN PROCESSING).Molecular Sequence Annotation: The addition of descriptive information about the function or structure of a molecular sequence to its MOLECULAR SEQUENCE DATA record.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Databases, Genetic: Databases devoted to knowledge about specific genes and gene products.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Ear: The hearing and equilibrium system of the body. It consists of three parts: the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR. Sound waves are transmitted through this organ where vibration is transduced to nerve signals that pass through the ACOUSTIC NERVE to the CENTRAL NERVOUS SYSTEM. The inner ear also contains the vestibular organ that maintains equilibrium by transducing signals to the VESTIBULAR NERVE.Labyrinth Diseases: Pathological processes of the inner ear (LABYRINTH) which contains the essential apparatus of hearing (COCHLEA) and balance (SEMICIRCULAR CANALS).Ear, Inner: The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (COCHLEA; VESTIBULAR LABYRINTH; and SEMICIRCULAR CANALS) in the TEMPORAL BONE. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (COCHLEAR DUCT; SACCULE AND UTRICLE; and SEMICIRCULAR DUCTS) forming a continuous space enclosed by EPITHELIUM and connective tissue. These spaces are filled with LABYRINTHINE FLUIDS of various compositions.Ear, Middle: The space and structures directly internal to the TYMPANIC MEMBRANE and external to the inner ear (LABYRINTH). Its major components include the AUDITORY OSSICLES and the EUSTACHIAN TUBE that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat.Ear, External: The outer part of the hearing system of the body. It includes the shell-like EAR AURICLE which collects sound, and the EXTERNAL EAR CANAL, the TYMPANIC MEMBRANE, and the EXTERNAL EAR CARTILAGES.Ear Diseases: Pathological processes of the ear, the hearing, and the equilibrium system of the body.Ear Canal: The narrow passage way that conducts the sound collected by the EAR AURICLE to the TYMPANIC MEMBRANE.Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.Vestibulocochlear Nerve Diseases: Pathological processes of the VESTIBULOCOCHLEAR NERVE, including the branches of COCHLEAR NERVE and VESTIBULAR NERVE. Common examples are VESTIBULAR NEURITIS, cochlear neuritis, and ACOUSTIC NEUROMA. Clinical signs are varying degree of HEARING LOSS; VERTIGO; and TINNITUS.Vestibulocochlear Nerve: The 8th cranial nerve. The vestibulocochlear nerve has a cochlear part (COCHLEAR NERVE) which is concerned with hearing and a vestibular part (VESTIBULAR NERVE) which mediates the sense of balance and head position. The fibers of the cochlear nerve originate from neurons of the SPIRAL GANGLION and project to the cochlear nuclei (COCHLEAR NUCLEUS). The fibers of the vestibular nerve arise from neurons of Scarpa's ganglion and project to the VESTIBULAR NUCLEI.Craniocerebral Trauma: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.Hearing Disorders: Conditions that impair the transmission of auditory impulses and information from the level of the ear to the temporal cortices, including the sensorineural pathways.Sick Building Syndrome: A group of symptoms that are two- to three-fold more common in those who work in large, energy-efficient buildings, associated with an increased frequency of headaches, lethargy, and dry skin. Clinical manifestations include hypersensitivity pneumonitis (ALVEOLITIS, EXTRINSIC ALLERGIC); allergic rhinitis (RHINITIS, ALLERGIC, PERENNIAL); ASTHMA; infections, skin eruptions, and mucous membrane irritation syndromes. Current usage tends to be less restrictive with regard to the type of building and delineation of complaints. (From Segen, Dictionary of Modern Medicine, 1992)Cochlear Nerve: The cochlear part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The cochlear nerve fibers originate from neurons of the SPIRAL GANGLION and project peripherally to cochlear hair cells and centrally to the cochlear nuclei (COCHLEAR NUCLEUS) of the BRAIN STEM. They mediate the sense of hearing.Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Knowledge Bases: Collections of facts, assumptions, beliefs, and heuristics that are used in combination with databases to achieve desired results, such as a diagnosis, an interpretation, or a solution to a problem (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed).Vestibular Nerve: The vestibular part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The vestibular nerve fibers arise from neurons of Scarpa's ganglion and project peripherally to vestibular hair cells and centrally to the VESTIBULAR NUCLEI of the BRAIN STEM. These fibers mediate the sense of balance and head position.Facial Nerve: The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and SALIVARY GLANDS, and convey afferent information for TASTE from the anterior two-thirds of the TONGUE and for TOUCH from the EXTERNAL EAR.Otolaryngology: A surgical specialty concerned with the study and treatment of disorders of the ear, nose, and throat.TennesseeOtorhinolaryngologic Diseases: Pathological processes of the ear, the nose, and the throat, also known as the ENT diseases.Otorhinolaryngologic Surgical Procedures: Surgery performed on the ear and its parts, the nose and nasal cavity, or the throat, including surgery of the adenoids, tonsils, pharynx, and trachea.Academic Medical Centers: Medical complexes consisting of medical school, hospitals, clinics, libraries, administrative facilities, etc.Psychology, Applied: The science which utilizes psychologic principles to derive more effective means in dealing with practical problems.Education, Professional: Formal education and training in preparation for the practice of a profession.Refsum Disease: An autosomal recessive familial disorder that usually presents in childhood with POLYNEUROPATHY; SENSORINEURAL HEARING LOSS; ICHTHYOSIS; ATAXIA; RETINITIS PIGMENTOSA; and CARDIOMYOPATHIES. (From Joynt, Clinical Neurology, 1991, Ch37, p58-9; Rev Med Interne 1996;17(5):391-8) This condition can be caused by mutation in the genes encoding peroxisomal phytanoyl-CoA hydroxylase or proteins associated peroxisomal membrane, leading to impaired catabolism of PHYTANIC ACID in PEROXISOMES.Phytanic Acid: A 20-carbon branched chain fatty acid. In phytanic acid storage disease (REFSUM DISEASE) this lipid may comprise as much as 30% of the total fatty acids of the plasma. This is due to a phytanic acid alpha-hydroxylase deficiency.Peroxisomal Disorders: A heterogeneous group of inherited metabolic disorders marked by absent or dysfunctional PEROXISOMES. Peroxisomal enzymatic abnormalities may be single or multiple. Biosynthetic peroxisomal pathways are compromised, including the ability to synthesize ether lipids and to oxidize long-chain fatty acid precursors. Diseases in this category include ZELLWEGER SYNDROME; INFANTILE REFSUM DISEASE; rhizomelic chondrodysplasia (CHONDRODYSPLASIA PUNCTATA, RHIZOMELIC); hyperpipecolic acidemia; neonatal adrenoleukodystrophy; and ADRENOLEUKODYSTROPHY (X-linked). Neurologic dysfunction is a prominent feature of most peroxisomal disorders.Refsum Disease, Infantile: An early onset form of phytanic acid storage disease with clinical and biochemical signs different from those of REFSUM DISEASE. Features include MENTAL RETARDATION; SENSORINEURAL HEARING LOSS; OSTEOPOROSIS; and severe liver damage. It can be caused by mutation in a number of genes encoding proteins involving in the biogenesis or assembly of PEROXISOMES.Zellweger Syndrome: An autosomal recessive disorder due to defects in PEROXISOME biogenesis which involves more than 13 genes encoding peroxin proteins of the peroxisomal membrane and matrix. Zellweger syndrome is typically seen in the neonatal period with features such as dysmorphic skull; MUSCLE HYPOTONIA; SENSORINEURAL HEARING LOSS; visual compromise; SEIZURES; progressive degeneration of the KIDNEYS and the LIVER. Zellweger-like syndrome refers to phenotypes resembling the neonatal Zellweger syndrome but seen in children or adults with apparently intact peroxisome biogenesis.PhytolMicrobodies: Electron-dense cytoplasmic particles bounded by a single membrane, such as PEROXISOMES; GLYOXYSOMES; and glycosomes.Music: Sound that expresses emotion through rhythm, melody, and harmony.Dancing: Rhythmic and patterned body movements which are usually performed to music.Percussion: Act of striking a part with short, sharp blows as an aid in diagnosing the condition beneath the sound obtained.Performance Anxiety: Anxiety related to the execution of a task. (Campbell's Psychiatric Dictionary, 9th ed.)Reactive Inhibition: Tendency toward a lessened strength of response due to practice or activity. It is independent of the effect of reward and is a direct function of time interval since the last response and the number of preceding responses.Music Therapy: The use of music as an adjunctive therapy in the treatment of neurological, mental, or behavioral disorders.Communication Aids for Disabled: Equipment that provides mentally or physically disabled persons with a means of communication. The aids include display boards, typewriters, cathode ray tubes, computers, and speech synthesizers. The output of such aids includes written words, artificial speech, language signs, Morse code, and pictures.

3D MRI of the membranous labyrinth. An age related comparison of MR findings in patients with labyrinthine fibrosis and in persons without inner ear symptoms. (1/37)

PURPOSE: We compared MRI of the membranous labyrinth in patients with chronic non-neoplastic inner ear disease and MR signs of labyrinthine fibrosis and controls depending on their age, in order to establish whether there were any MR differences regarding patient age groups, control age groups and between the patients and controls themselves. MATERIALS AND METHODS: Clinical ENT examinations as well as a T2* weighted 3D CISS (Constructive Interference in Steady State) sequence with a slice thickness of 0.7 mm were performed. Our collective was subdivided as follows: 0-19 years (10 controls, 3 patients with chronic non-neoplastic inner ear disease), 20-49 years (55 controls, 8 patients), 50 years and older (40 controls, 22 patients). Detectability of labyrinthine structures (e.g. cochlea, vestibule, semicircular canals) and filling defects were evaluated. RESULTS: In the 3 age-groups of the control collective no significant differences were observed in the membranous labyrinth. However differences concerning labyrinthine detectability emerged between controls and patients in both the 20-49 years and 50 years and older age groups. In the patient collective the 3 age groups showed no significant discrepancy in the mean number of lesions. CONCLUSION: Filling defects of the membranous labyrinth on 3D CISS MR images are pathological even in older persons. We would therefore recommend high resolution T2* weighted MRI in the case of suspected labyrinthine fibrosis.  (+info)

Ototoxicity: an argument for evaluation of the cochlea in safety testing in animals. (2/37)

The cochlea is one of the more common targets for toxic effects, yet current toxicologic screening in animals does not routinely evaluate the cochlea as a potential target organ. Although histopathologic sections are routinely taken from the eye and the optic nerve and tract and most studies include at least 1 section through the nasal cavity and olfactory mucosa, the cochlea is not histopathologically examined in routine toxicity studies. Unfortunately, routine clinical examinations frequently miss ototoxicity because rodents and other species can lose most of their high-frequency hearing and still respond to most ambient noises. Ototoxicity as a deficiency in toxicologic screening can be remedied by using well-established histopathologic and behavioral methods or electrophysiologic methods, such as brain stem auditory evoked responses (BAERs). Once the equipment is in place, BAERs can be obtained quickly and easily for ototoxicity screening (approximately 15 minutes for paired testing of 2 rats and 30 minutes each for dogs). BAERs also can be used in virtually all mammalian species. Three or 4 probe frequencies (eg, 4, 8, 16, and 32 kHz), representing different areas of the cochlea, can be tested in a few minutes with subcutaneous electrodes under short-acting chemorestraint. Given the availability of several approaches to screening for ototoxicity and the importance of the auditory function in human health, safety tests of chemicals and drugs should include an effective screening test for ototoxicity.  (+info)

Spiral ligament pathology: a major aspect of age-related cochlear degeneration in C57BL/6 mice. (3/37)

Data from systematic, light microscopic examination of cochlear histopathology in an age-graded series of C57BL/6 mice (1.5-15 months) were compared with threshold elevations (measured by auditory brain stem response) to elucidate the functionally important structural changes underlying age-related hearing loss in this inbred strain. In addition to quantifying the degree and extent of hair cell and neuronal loss, all structures of the cochlear duct were qualitatively evaluated and any degenerative changes were quantified. Hair cell and neuronal loss patterns suggested two degenerative processes. In the basal half of the cochlea, inner and outer hair cell loss proceeded from base to apex with increasing age, and loss of cochlear neurons was consistent with degeneration occurring secondary to inner hair cell loss. In the apical half of the cochlea with advancing age, there was selective loss of outer hair cells which increased from the middle to the extreme apex. A similar gradient of ganglion cell loss was noted, characterized by widespread somatic aggregation and demyelination. In addition to these changes in hair cells and their innervation, there was widespread degeneration of fibrocytes in the spiral ligament, especially among the type IV cell class. The cell loss in the ligament preceded the loss of hair cells and/or neurons in both space and time suggesting that fibrocyte pathology may be a primary cause of the hearing loss and ultimate sensory cell degeneration in this mouse strain.  (+info)

Delayed inner ear maturation and neuronal loss in postnatal Igf-1-deficient mice. (4/37)

Insulin-like growth factor-1 (IGF-1) has been shown to play a key role during embryonic and postnatal development of the CNS, but its effect on a sensory organ has not been studied in vivo. Therefore, we examined cochlear growth, differentiation, and maturation in Igf-1 gene knock-out mice at postnatal days 5 (P5), P8, and P20 by using stereological methods and immunohistochemistry. Mutant mice showed reduction in size of the cochlea and cochlear ganglion. An immature tectorial membrane and a significant decrease in the number and size of auditory neurons were also evident at P20. IGF-1-deficient cochlear neurons showed increased caspase-3-mediated apoptosis, along with aberrant expression of the early neural markers nestin and Islet 1/2. Cochlear ganglion and fibers innervating the sensory cells of the organ of Corti presented decreased levels of neurofilament and myelin P(0) in P20 mouse mutants. In addition, an abnormal synaptophysin expression in the somata of cochlear ganglion neurons and sensory hair cells suggested the persistence of an immature pattern of synapses distribution in the organ of Corti of these animals. These results demonstrate that lack of IGF-1 in mice severely affects postnatal survival, differentiation, and maturation of the cochlear ganglion cells and causes abnormal innervation of the sensory cells in the organ of Corti.  (+info)

Dynamics of noise-induced cellular injury and repair in the mouse cochlea. (5/37)

To assess the dynamics of noise-induced tissue injury and repair, groups of CBA/CaJ mice were exposed to an octave-band noise for 2 hours at levels of 94, 100, 106, 112, or 116 dB SPL and evaluated at survival times of 0, 12, 24 hours or 1, 2, or 8 weeks. Functional change, assessed via auditory brainstem response (ABR), ranged from a reversible threshold shift (at 94 dB) to a profound permanent loss (at 116 dB). Light microscopic histopathology was assessed in serial thick plastic sections and involved quantitative evaluation of most major cell types within the cochlear duct, including hair cells (and their stereocilia), supporting cells, ganglion cells, spiral ligament fibrocytes, spiral limbus fibrocytes, and the stria vascularis. Morphometry allowed patterns of damage to be systematically assessed as functions of (1) cochlear location, (2) exposure level, and (3) postexposure survival. Insights into mechanisms of acute and chronic noise-induced cellular damage are discussed.  (+info)

Acrylonitrile produces transient cochlear function loss and potentiates permanent noise-induced hearing loss. (6/37)

There is growing evidence that agents that produce oxidative stress in the cochlea have significant ototoxic potential by themselves and can potentiate noise-induced hearing loss as well. Acrylonitrile (ACN) metabolism entails conjugation with glutathione, resulting in rapid and pronounced depletion of this important antioxidant in many organs including brain, liver, and kidney. ACN metabolism also results in cyanide (CN) formation through a secondary oxidative pathway. The results of two physiological experiments are reported here. First, the acute effects of ACN (50 mg/kg sc) on auditory sensitivity are assessed using a within subject study. In the second study, persistent effects of ACN alone (50 mg/kg, sc and 2 x 50 mg/kg, sc) and ACN in combination with noise exposure (8 h, 108 dB octave-band noise) are evaluated using threshold sensitivity as the dependent measure. Auditory threshold shift and absolute thresholds were determined using the compound action potential (CAP) amplitude. Acute ACN administration produces a loss in auditory threshold sensitivity that reached a maximum 10-20 min following sc injection. Auditory thresholds returned to control levels 75-100 min following exposure. In the study of permanent auditory threshold shifts, ACN plus noise increased auditory threshold impairment relative to rats receiving noise only when thresholds were assessed 3 weeks following exposure. ACN by itself did not produce permanent threshold impairment 3 weeks following administration. Assays were undertaken in separate groups of rats to track the elevation in blood CN and the depletion of total glutathione in cochlea, brain, and liver following ACN treatment. Systemic blood CN levels were not significantly elevated until 60-120 min following injection, and cochlear glutathione levels showed significant depletion as little as 15 min after injection and remained depressed for about 4 h. The results confirm the prediction that ACN is acutely ototoxic and can enhance noise-induced hearing loss.  (+info)

Myo15 function is distinct from Myo6, Myo7a and pirouette genes in development of cochlear stereocilia. (7/37)

The unconventional myosin genes Myo15, Myo6 and Myo7a are essential for hearing in both humans and mice. Despite the expression of each gene in multiple organs, mutations result in identifiable phenotypes only in auditory or ocular sensory organs. The pirouette (pi) mouse also exhibits deafness and an inner ear pathology resembling that of Myo15 mutant mice and thus may be functionally related to Myo15. In order to investigate possible interactions between Myo15 and Myo6, Myo7a, and the gene affected in pirouette, we crossed Myo15(sh2/sh2) mice to the three other mutant mouse strains. Hearing in doubly heterozygous mice was similar to age-matched singly heterozygous animals, indicating that partial deficiency for both Myo15 and one of these other deafness genes does not reduce hearing. Viable double mutants were obtained from each cross, indicating that potential overlapping functions between these genes in other organs are not essential for viability. All critical cell types of the cochlear sensory epithelium were present in double mutant mice and cochlear stereocilia exhibited a superimposition of single mutant phenotypes. These data suggest that the function of Myo15 is distinct from that of Myo6, Myo7a or pi in development and/or maintenance of stereocilia.  (+info)

Abnormal auditory brainstem responses and cochlear pathology in rats induced by an exaggerated styrene exposure regimen. (8/37)

Groups of 12 male 42-day-old rats were exposed to 0 or 800 ppm styrene vapors for 14 hr/day, 5 days/week for 3 weeks. Tone-pip auditory brainstem responses (ABRs) at 4, 8, 16, and 30 kHz were obtained after the last exposure. ABRs were minimally affected at 4 kHz and moderately to severely affected at 8, 16, and 30 kHz as indicated by waveforms which had a decreased amplitude and increased latency as compared to the controls. Missing outer hair cell(s) were evident in the basal and lower middle turns of the organ of Corti. Outer hair cell loss was least in the first row and greatest in the second and third rows. Occasional inner hair cells were also missing in regions of severe outer hair cell loss. The distribution of hair cell loss within the cochlea was consistent with the pattern of ABR alterations. These data document mid-frequency auditory dysfunction in styrene-exposed young adult rats with significant damage to the organ of Corti following an exaggerated styrene exposure regimen.  (+info)

*List of MeSH codes (C09)

... cochlear diseases MeSH C09.218.568.217 --- endolymphatic hydrops MeSH C09.218.568.217.500 --- meniere's disease MeSH C09.218. ... auditory diseases, central MeSH C09.218.807.186.094 --- auditory perceptual disorders MeSH C09.218.807.186.432 --- hearing loss ... central MeSH C09.218.807.800 --- vestibulocochlear nerve diseases MeSH C09.218.807.800.675 --- neuroma, acoustic MeSH C09.218. ... 568.315 --- labyrinthitis MeSH C09.218.568.900 --- vestibular diseases MeSH C09.218.568.900.883 --- vertigo MeSH C09.218. ...

*Refsum disease

Nogueira, C.; Meehan, T. & O'Donoghue, G. (2014). "Refsum's Disease and Cochlear Implantation". Annals of Otology, Rhinology, ... Adult Refsum disease should not be confused with infantile Refsum disease, a peroxisome biogenesis disorder resulting from ... Refsum disease, also known as classic or adult Refsum disease, heredopathia atactica polyneuritiformis, phytanic acid oxidase ... that contain lipid accumulations Adult Refsum disease may be divided into the adult Refsum disease 1 and adult Refsum disease 2 ...

*Hearing loss

Autoimmune disease is recognized as a cause for cochlear damage. Although rare, it is possible for autoimmune processes to ... NAD Cochlear Implant Committee. "NAD Position Statement on Cochlear Implants (2000)". Cochlear Implants %7c National ... Cochlear implants improve outcomes in people with hearing loss in either one or both ears. They work by artificial stimulation ... Cochlear implants as well as bone conduction implants can help with single sided deafness. Middle ear implants or bone ...

*Neurotology

... surgery of the endolymphatic sac for meniere's disease and cochlear implant surgery, because of the additional risk of hearing ... Conditions treated by neurotologists include: Vestibular (balance) diseases, such as Ménière's disease and vestibular ... Otology generally refers to the treatment of middle ear disease and resultant conductive hearing loss, whereas neurotology ...

*Cogan syndrome

Occasionally, if the disease has damaged blood vessels, cochlear implantation may need to be done to correct the problem. ... The classic form of the disease was first described by D.G. Cogan in 1945. Cogan's syndrome is a rare, rheumatic disease ... For more severe disease, oral corticosteroids may be necessary to reduce the inflammatory response. When large amounts of ... It is currently thought that Cogan's syndrome is an autoimmune disease. The inflammation in the eye and ear are due to the ...

*Multielectrode array

Deep brain stimulation (DBS) has been effective at treating movement disorders such as Parkinson's disease, and cochlear ... Immunohistochemical markers showed a surprising presence of hyperphosphorylated tau, an indicator of Alzheimer's disease, near ...

*CI

... used as a measure of disease frequency in epidemiology Cochlear implant Chemical injury syndrome, an increased sensitivity to ...

*International Federation of Hard of Hearing People

This includes late deafened adults, cochlear implant users, and people who experience Tinnitus, Meniere's disease, Hyperacusis ...

*The Traveling Awareness Bears

Cochlear implant, Celiac or Coeliac disease, Congenital Adrenal Hyperplasia, Congenital heart defect, Cortical blindness, ... medical disciplines and genetic diseases programs.The organization's purpose is to help children with pediatric diseases to " ... Some bears are not for specific diseases but support for children and doctors. These include a bear for bullying and bears for ... Each bear has a specific name, disease, and shirt. Some bears are specialized with crutches, masks, hearing aids, and other ...

*Remote control animal

... and the microstimulation used in the treatments of Parkinson's disease (Deep Brain Stimulation) and deafness (Cochlear implants ...

*Neuroprosthetics

... sensory or cognitive modality that might have been damaged as a result of an injury or a disease. Cochlear implants provide an ... Cochlear implants have been very successful among these three categories. Today the Advanced Bionics Corporation, the Cochlear ... Cochlear and brainstern auditory prostheses "neural interface for hearing restoration: Cochlear and brain stem implants". ... Proceedings of the Ieee 96:1076-84 J. K. Niparko and B. W. Wilson, "History of cochlear implants," in Cochlear Implants: ...

*Ménière's disease

The corresponding subtypes of MD are called vestibular MD, showing symptoms of vertigo, and cochlear MD, showing symptoms of ... Finally in 1995, the list was again altered to allow for degrees of the disease: Certain - Definite disease with ... Ménière's disease (MD) is a disorder of the inner ear that is characterized by episodes of feeling like the world is spinning ( ... Ménière's disease usually starts confined to one ear; it appears that it extends to both ears in about 30% of cases. People may ...

*Synaptopathy

This cochlear synaptopathy has been seen after prolonged noise exposure in both primate and non-primate models. Two possible ... Some diseases of unknown etiology have been proposed to be synaptopathies. Examples include autism spectrum disorder and ... Age-related cochlear synaptic and neural degeneration has also been demonstrated in mice. Molecules such as FMRP1 act as ... A synaptopathy is a disease of the brain, spinal cord or peripheral nervous system relating to the dysfunction of synapses. ...

*EPS8

... encoding an actin-binding protein of cochlear hair cell stereocilia, is a new causal gene for autosomal recessive profound ... deafness". Orphanet Journal of Rare Diseases. 9 (1): 55. doi:10.1186/1750-1172-9-55. PMC 4022326 . PMID 24741995. EPS8 has been ...

*Electropalatography

... children with cochlear implants, children with cerebral palsy and adults with Parkinson's disease. Therapy has proved to be ...

*Implant (medicine)

... as well as middle ear diseases such as otitis media; and neurological diseases such as epilepsy, Parkinson's disease, and ... In some cases implants contain electronics e.g. artificial pacemaker and cochlear implants. Some implants are bioactive, such ... "Upper G.I. Surgery - Gastroesophageal Reflux Disease (GERD)". Keck School of Medicine of USC. Retrieved 12 March 2016. "Gastric ... They are used to treat conditions such as heart failure, cardiac arrhythmia, ventricular tachycardia, valvular heart disease, ...

*Madras motor neuron disease

... neural depletion and gliosis of the cochlear nucleus on both sides of the brainstem, and demyelination and axonal loss of the ... Madras motor neuron disease (MMND) is a rare motor neuron disease originating in South India. Two other forms of the disease ... Madras motor neuron disease (MMND) is a motor neuron disease affecting primarily lower motor neurons. It is similar to ... Navaneetham, Duraiswamy (February 2010). "Madras Motor Neuron Disease". Foundation for Research on Rare Diseases and Disorders ...

*Ototoxicity

Cochlear implants are sometimes an option to restore hearing. Such treatments are typically taken to comfort the patient, not ... Renal:An integrated approach to disease. McGraw Hill, New York NY 2012, pg 123 Rademaker-Lakhai JM, Crul M, Zuur L, et al. ( ... The time frames for progress of the disease vary greatly and symptoms of hearing loss may be temporary or permanent. The ... Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which ...

*Ear Research Foundation

They also host several support group meetings including Tinnitus and Cochlear Implant Support Group Meetings. The Ear Research ... Foundation also provides medical care, treatment, and rehabilitation of ear diseases and hearing and balance disorders. ... The Ear Research Foundation clinic has treated 35,000 children and has performed over 8000 surgeries including many cochlear ...

*Reactive oxygen species

Memory capabilities decline with age, evident in human degenerative diseases such as Alzheimer's disease, which is accompanied ... They may also be involved in hearing impairment via cochlear damage induced by elevated sound levels, in ototoxicity of drugs ... Watson JD (Mar 2014). "Type 2 diabetes as a redox disease". Lancet. 383 (9919): 841-3. doi:10.1016/s0140-6736(13)62365-x. PMID ... Molenaar RJ, van Noorden CJ (Sep 2014). "Type 2 diabetes and cancer as redox diseases?". Lancet. 384 (9946): 853. doi:10.1016/ ...

*NYU Langone Medical Center

Howard Cosell ... died yesterday at the Hospital for Joint Diseases in Manhattan. He was 77. ... Official website NYU School of ... Cochlear Implant Center, Sleep Disorders Center, Dysautonomia Center, and programs ranging from maternal-fetal medicine to ... In the early 1980s, clincians and researchers at NYU School of Medicine, including dermatologists, infectious disease ... and venereal disease; the development of vaccines for hepatitis B, polio, and cancer; advances in the treatment and prevention ...

*Retinal implant

These diseases cause blindness by affecting the photoreceptor cells in the outer layer of the retina, while leaving the inner ... The development of retinal implants has also been motivated in part by the advancement and success of cochlear implants, which ... "FDA approves first retinal implant for adults with rare genetic eye disease". fda.gov. U.S. Food and Drug Administration. 14 ... The system is meant to partially restore useful vision to people who have lost their photoreceptors due to retinal diseases ...

*Neuromodulation

Parkinson's disease is at least in part related to dropping out of dopaminergic cells in deep-brain nuclei, primarily the ... such as in cochlear implants), relief of pain, or control of symptoms, such as tremor seen in movement disorders like ... Parkinson's disease. The therapies consist primarily of targeted electrical stimulation, or infusion of medications into the ...

*Melanin

Lewy Body Disease Archived 2009-07-21 at the Wayback Machine.[full citation needed] Meyskens FL, Farmer P, Fruehauf JP (June ... Instead the absence of melanocytes in the stria vascularis of the inner ear results in cochlear impairment, though why this is ... In Parkinson's disease, a disorder that affects neuromotor functioning, there is decreased neuromelanin in the substantia nigra ... This hypothesis is supported by the fact that the loss of neuromelanin observed in Parkinson's disease is accompanied by an ...

*NMDA receptor

Most notably excitotoxic events involving NMDA receptors have been linked to Alzheimer's disease and Huntington's disease as ... Cochlear NMDARs are the target of intense research to find pharmacological solutions to treat tinnitus. NMDARs are associated ... Excitotoxicity is implied to be involved in some neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease ... Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis. Blocking of NMDA receptors could therefore, in ...

*Susac's syndrome

Hearing aids or cochlear implants may be necessary in the event of hearing loss. Lian K, Siripurapu R, Yeung R, Hopyan J, Eng K ... Susac's syndrome is a very rare disease, of unknown cause, and many persons who experience it do not display the bizarre ... Despite this being an extremely rare disease, there are 4 registries collecting data on the illness; two are in the United ... The latest thinking is that an antibody directed against endothelial cells is the pathogenic mechanism in this disease which ...
Salicylate (aspirin) is a widely used drug in clinics. Acute application of salicylate may cause reversible hearing loss, reduction of distortion product otoacoustic emission (DPOAE), and loss of outer hair cell (OHC) electromotility. A long-term application may cause tinnitus. Interestingly, it has been reported that a long-term salicylate application up-regulated expression of prestin, the OHC m
Our results indicate that cochlear neurons in the basal turn degenerate in the absence of NT-3 because BDNF is not expressed in the basal turn epithelium at a critical time. As predicted by this interpretation, transgenic expression of BDNF under control of the NT-3 promoter qualitatively rescues this innervation deficit at E13.5 (Fig. 2 D). A similar rescue has been found in newborn transgenic mice (Coppola et al., 2001). However, we cannot exclude the possibility that the additional availability of excess BDNF in itself is related to the observed rescue. Nevertheless, because there is some endogenous expression ofBDNF in developing hair cells of the middle and apical turns, sensory neurons innervating these regions are partially rescued by this neurotrophin in NT-3 null mutants. BDNFexpression, though, must not be high enough to compensate completely for the loss of NT-3. The specific loss of cochlear neurons in the apical turn of BDNF homozygous mutants may reflect insufficient expression of ...
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The MiTiHeart® LVAD has been extensively evaluated in both in vitro and in vivo animal studies. The LVAD system has been successfully subjected to more than 5,000 hours of in vitro testing and 2,000 hours of animal implant testing. The latest MiTiHeart® LVAD system is compact, efficient and capable of long-term stable operation in vitro and in vivo. A total input power of 6 W was required at a design point of 4,100 rpm while pumping 5 L/min against 100 mmHg. This is among the lowest power reported by magnetically levitated LVADs found in literature. In Vitro testing showed low hemolysis under non-pulsatile and pulsatile conditions. NIH values are among the lowest reported in literature. Long-term durability testing has been demonstrated for 63 days of continuous operation while submerged in saline. Two successful chronic implant studies were performed. In both studies, the MiTiHeart® LVAD operated as expected with no device related complications. Recent test results will allow the MiTiHeart® ...
This page provides relevant content and local businesses that can help with your search for information on Border Collie Breeders. You will find informative articles about Border Collie Breeders, including Border Collie Information, Pictures of Border Collies. Below you will also find local businesses that may provide the products or services you are looking for. Please scroll down to find the local resources in Fremont, CA that can help answer your questions about Border Collie Breeders.
This page provides relevant content and local businesses that can help with your search for information on Border Collie Breeders. You will find informative articles about Border Collie Breeders, including Border Collie Information, Pictures of Border Collies. Below you will also find local businesses that may provide the products or services you are looking for. Please scroll down to find the local resources in Yonkers, NY that can help answer your questions about Border Collie Breeders.
en] Peripherin is an intermediate filament protein that is expressed in peripheral and enteric neurons. In the cochlear nervous system, peripherin expression has been extensively used as a differentiation marker by preferentially labeling the type II neuronal population at adulthood, but yet without knowing its function. Since the expression of peripherin has been associated in time with the process of axonal extension and during regeneration of nerve fibers in other systems, it was of interest to determine whether peripherin expression in cochlear neurons was a static phenotypic trait or rather prone to modifications following nerve injury. In the present study, we first compared the expression pattern of peripherin and beta III-tubulin from late embryonic stages to the adult in rat cochlea. The staining for both proteins was seen before birth within all cochlear neurons. By birth, and for 2 or 3 days, peripherin expression was gradually restricted to the type II neuronal population and their ...
Tinnitus is the phantom perception of noise in the ears that occurs in the absence of an external sound source. It is estimated that about 1 in 5 people experience tinnitus. Tinnitus by itself is not a disease but may be a symptom of another condition. In addition to a ringing sound, the noise may be perceived as buzzing, roaring, crickets, the ocean, or even music. A special variant of tinnitus, pulsatile tinnitus, is hearing ones heartbeat in one or both ears. Both pulsatile and non-pulsatile tinnitus may be constant or intermittent. The source of the tinnitus can be the ear itself; however, tinnitus is far more commonly of central origin (from the brain). The inciting event for tinnitus may be a change in inner ear function; however, the tinnitus generator is likely to be somewhere in the brains auditory circuitry (central auditory pathways). Some of the most common causes include age-related hearing loss, exposure to loud noises, earwax impaction, certain medications, or a stiffening of ...
Natural News) Everyone experiences tinnitus every once in a while, but it becomes a cause for worry when it persists longer than it usually does. According to a study published in the Caspian Journal of Internal Medicine, sufferers of chronic non-pulsatile tinnitus can find relief in acupuncture, concluding that the ancient healing art can reduce the severity of this issue.. If you have ever experienced hearing a ringing sound within your ears, you have most likely experienced tinnitus. Its not a condition per se - rather, it is a symptom of what is possibly an underlying condition. These could include hearing loss, an ear injury, or even a disorder affecting your circulatory system. However, tinnitus may also be nothing serious, occurring as simply the after-effect of certain stimuli, such as very loud noises.. There are two types of tinnitus:. Pulsatile tinnitus is so-called because it sounds like either your pulse or the movement of your muscles. This is usually caused by problems in the ...
All purebred dogs are subject to certain hereditary diseases, border collies included. Your super-active, super-smart border collie might appear to be Superdog, but its possible he harbors genes ...
Meet Tango the Australian Cattle Dog / Border Collie on the Daily Puppy. Read about Tango, the Australian Cattle Dog / Border Collie or any other breed of dog. Connect with other dog owners on DailyPuppy.com.
Sugarfoot is my rescue Border Collie. She has served me as an Assistance Dog, and been my best friend. Shes a sweet, brilliant dog with boundless heart and energy. But she needs help now, that I cant give her. Last week Sugarfoot ruptured the cruciate ligament in her left rear leg, while chasing ...
Dogs arent usually associated with clean beaches. But new research has recognized border collies for their ability to chase off gulls that foul beach water and sand with their droppings. The experiment was launched two years ago by researchers at Central Michigan University who were asked by the...
Hello All, My wife and I recently adopted a 2 year old border collie mix from a rescue group. We were surprised to learn after the adoption...
Hi Doctor, from Surrey in The UK, We have a gorgeous Border Collie pup. We think he is about 6 months old. Hes a clever little th...
Kennel Club Genetics Centre at the Animal Health Trust makes breakthrough discovery in identifying the genetic mutation responsible for sensory neuropathy
This test is for inheritance of the chromosome (TNS+ haplo) known to carry the TNS mutation. NICE OF YOU TO COME BYE TRI BFORE U DIE did NOT inherit this chromosome from one of its parents, PIONEER PAINTED PRAIRIE VON DER KLEINE ARCHE or NICE OF YOU TO COME BYE REDWICK REBEL ...
The knowledge from the previous articles provides us with an instrument to assess the result of a mating and to see which combinations would better not be used ...
Nine patients qualified for surgery for a bleeding gastric ulcer - all had a visible vessel. Three of these vessels were thrombosed including 2 in patients who had been in shock. The smallest patent vessel was 0,35 mm in diameter, and 6 of the bleeding vessels were subserosal. The features thought to predispose to further bleeding were vessel size, a lateral hole in the main trunk of the vessel and, possibly, previous recanalization or ingestion of a drug which affected haemostasis. Five of 6 patent arteries had a cap of thrombus over the breach forming a false aneurysm. It is suggested that clinically these should pulsate, enlarge, leak - with persistent fresh thrombus in the ulcer crater on repeat endoscopy - and finally rupture. Where the underlying vessel is thrombosed the stigmata of a non-pulsatile visible vessel or thrombus in the ulcer should disappear on repeat endoscopy. The sizes of the arteries in the normal antrum are tabulated.. ...
Hello, I have been taking care of dogs almost my whole life. Currently I have the lovable Layla, a very well behaved Border Collie. She is very sub...
humane society rescue, border collie / lab mix according to the lady, female, 12~ weeks old, very sweet personality from what i have...
In 2010 I adopted a 5 week old puppy. Lets call him R-dawg. I didnt know he was that young. I also didnt know that the lady I got him from was running a puppy mill, not working for a shelter like she claimed. I thought and was told that he was a border collie.…
Im a big dog lover. I always had a dog growing up. I had a border collie when I was a kid she was my best friend. We played in are yard and took h...
Photograph of Black-and-white Border Collie bitch pup, Ice, 9 weeks old, with Black-and-white Guinea pig and rabbit. Rights managed white background Pets image. Warren Photographic WP35748
Page 1 of 2 - OT (Sorry) - Cat Food - posted in General Border Collie Discussion: Since the Boards are a little slow these days, I thought I could slip in a off-topic cat question. I know many folks here have done extensive research on the best diet/food for their dogs and I am impressed with your knowledge. With that in mind, what do you feed your cats? I have a 13-year old skinny cat and an 8-year old fat cat. The older cat has always eaten dry Purina Cat Chow because it was what wa...
Border Collies are lively and full of energy. Originally bred as working dogs, theyll want to herd anything, including young members of the family! Read more here.
Details about canine genetic testing for the product: Sensory Neuropathy (Border Collie Type), for the breed: Old English Sheepdog.
Question - I have a border collie named jenny.she has been over weight - J6. Find the answer to this and other Dog questions on JustAnswer
Our border collie might have ingested 75 mg. Cymbalta, and 20 mg. lisinopril. She weighs about 8 pounds. Will she be - Answered by a verified Dog Veterinarian
The rabies vaccine is arguably the most dangerous shot our dogs get. Because its required by law, its a difficult shot to avoid. Because the vaccine is made from a "killed" virus, rather than "modified live" virus as are the other important "core" vaccines, manufacturers add dangerous "adjuvants" to boost effectiveness. These adjuvants too often cause adverse reactions, some of which occur quickly, but many of which occur days, weeks or even months after vaccination. A "killed" vaccine (rather than one from a modified live virus), the rabies vaccine contains adjuvants (chemical boosters) to enhance the immunological response. In 1999, the World Health Organization "classified veterinary vaccine adjuvants as Class III/IV carcinogens with Class IV being the highest risk." ...
Border Collies were bred as herding dogs in the countryside between Scotland and England. They are active dogs that do best when they have a job. Learn more...
Why is it called a Collie? It doesnt look like a Collie!. Collie is a Scottish word for dogs that herd sheep, hence the Border Collie, the Rough (Lassie-type) or Smooth Collie and the Bearded Collie. This may have come from the Coaley or black-faced sheep in Scotland.. Are they good family dogs?. Beardies are people-oriented dogs. They NEED to be with their family. If left alone for long periods, they are liable to become frustrated and provide their own entertainment - not always one that makes the owner happy.. Beardies are vigorous, bouncy dogs, and like to jump up to look you in the eyes or kiss your nose. This fits in well with many families. Others, particularly those with toddlers, non-doggy visitors, elderly or physically challenged people, prefer to train their Beardie to sit and shake instead of jumping on people to greet them. Some Beardies have a high herding instinct and nip at ankles or eye-level bottoms, trying to bunch their "flock." Like kids, some are more rowdy than others. ...
Sparrow is finally, finally, dare I say it, having consistently lovely poops after weeks of on-again-off-again mysterious intestinal unhappiness. Knock wood, cross my fingers, toss salt over my shoulder ...
Merry Meet from Wollongong, Australia! I am 51y.o.; happily married (2nd time lucky); mother/friend of my beautiful 22y.o. daughter; & we share our home with 2 beautiful doggies (cream/white border collie girl & smooth coated boy) and 20+ gorgeous ferrets! On 1st April (my wonderful hubbys birthday) 2014 I had gastric sleeve surgery. The Lap Band port failed within 6-12 months after surgery. The Band slipped and had to be surgically removed last year, after almost all the weight Id lost with it (approx 30 kgs) had been regained ...
OrigNorCalGal suggests: November one, 2014 at six:27 pm Thank you Much for your clarification and easy responses! I am appalled at many of the solutions mentioned by way of a Goggle search. Especially from groomers and demonstrate-Canine-folks wherever quite a few suggested exceptionally perilous things so your dog would glimpse very good during the clearly show ring or for photos, and so important link on. A lot of of these ideas would lead to significant eye distress/discomfort plus some even blindness (most counsel you More Help "check out closely so the item ie: bleach, hydrogen peroxide, cornstarch, and many others dies not get To the dogs eyes) My four week aged Border Collie puppies seem to have some added tearing, which demonstrates as reddish-brown within the whiter kinds (which I have not observed before on my dogs or prior litters years back -distinctive dogs/similar breed) although the ARE teething, so ...
6:30 this morning. I was holding her paw. For those that dont know she was my Mama dog, Border Collie, eldest. My husband will be able to comfort her there. I cant. I know words of comfort will be coming but I cant read or type any more for awhile. My eyes and heart are leaking terribly. Laurie
I wanted to thank the awesome people that have watched over our two dogs and other two dogs before. I have been with the River Road Clinic for over 25 yrs. You have seen us through the death of two beloved dogs and now watch over our two present dogs. Our 13yr. old cocker spaniel is blind and deaf and you are helping me give her quality care. You have helped my border collie with behavior issues and regular health care. I recommend you to my friends and two of them have come to you. Thank you everyone! ...
I am brand new here and really need some help! My 7yr old border collie was diagnosed yesterday with aggressive fibrosarcoma of her upper... - Page 2
Okay, my dog Faris is a border collie, samoyed mix. He has no doggy odor and gets 1-2 baths a year, just because his coat gets dirty now and again....
Merle has never been common among working border collies: great working merles are rare as hens teeth. Im no geneticist, but its my understanding that a merle pup can only be produced if one of the parents is merle --- the last thing a breeder of good working stockdogs is going to care about. It doesnt help that breeding for merle carries a certain amount of risk, as in, you can kill some of the puppies now, or you can kill them later. Quoting from the GenMARK site: ...
AFTER Badger the border collie fractured his leg and failed to recover enough, there were fears he wouldnt see his second birthday.
Recently my vet said Skittles my border collie has a 4/6 heart murmur. Shes been put on Hills Science H/D diet. She is weighs a shocking 68 pounds and should only weigh 45-50 but the vet didnt say an...
Border Collie Rescue is a UK based charity, working Internationally to Rescue and Re-home Border Collies and Working Sheepdogs and promote a better understanding of the breed and its Welfare.
Controversy on superiority of pulsatile versus non-pulsatile extracorporeal circulation in cardiac surgery still continues. Stroke as one of the major adverse events during cardiopulmonary bypass is, in the majority of cases, caused by mobilization o
Polar was my beautiful boy-a 9 yo Great Dane that I had to euthanize this past April due to his degeneration from Wobblers Disease, which is a genetic/traumatic disorder that can affect large breed dogs. He is survived by his sister Pearl-who is my blind and deaf spitfire of an independent lady, Pauli-the smartest dog alive who is a 12 yo chocolate lab/border collie cross, and Sadie-a PITA 4 year old Jack Russell who owns us. Polar is kept company at the bridge by Guinness-one bad-ass lab/chow cross who never met an authority figure he didnt pretend to be deaf around, Taiga-another sweet deaf Dane who succumbed to Wobblers, and Daisy-a no nonsense Yorkie who no doubt runs that company of misfits ...
Anyway I apologised to her several times, feeling awful that she had fallen over my dog. I guess I thought it was over until I heard the story being repeated, apparently Mikey had "lunged" out at her dog!! ER...NO...Mikey simply got in the bloody way! By late morning the story amongst Border Collie enthusiasts was that he had barked at the other dog as well...BLOODY HELL..... NO!!! Poor Mikey simply moved into the wrong place at the wrong time, and was actually lucky not to get hurt himself!!! I cant believe how a small incident was exaggerated like that, just completely blown out of proportion. Theres now more than one person a little hurt because actually Im devastated that some people who didnt see the incident will believe that Mikey actually did lunge out and bark at the other dog, when simply like I said all he did was get in the bloody way ...
Meet Cade, our new foster dog. He was previously called Pepper but that didnt seem like a good border collie name to me so I changed it. "Cade" is Irish/Welsh for "small battle" in case you wondered. Although some of the details have been lost in translation the story is that his owner was moving, couldnt take him or find him a home and left him at the vet to be put to sleep. The vet didnt, and instead neutered him and called the shelter. The shelter was full and a volunteer took him from the vet to her home and somehow a friend of mine in the area was contacted. Anyway she was able to get him evaluated and it all fell together for her to bring him to the trial for me to take home. So here he is ...
Wisdom Panel Insights Dog DNA test reveals what breeds are in a mixed-breed dog. In my dogs case, I found out she is Alaskan malamute, Old English sheepdog, Australian shepherd, and border collie
Do you remember the 1950s show Lassie featuring a gorgeous and courageous dog? Lassie was the dog who sent the Collie breed to the spotlight.
(CNN) -- Never one to mince words, Sen. Harry Reid, D-Nevada, lumped supporters of Bunkerville rancher Cliven Bundy in with the Eric Rudolphs, Richard Reids and Timothy McVeighs.
I have a 13 year old short hair border collie beagle mix, fo r2-3 years she has had bladder control issues. Weve been to a few different vets and ran I have a 13 year old short hair border collie beagle mix, fo r2-3 years she has had bladder control issues. Weve been to a few different vets and ran tons of tests, 2years ago one of them said shed only live a month or two. The only thing I found to stop the accidental urination was changing her diet (on my own ) to Cooked grd. Beef, brown rice & green beans. We have now supplemented it with chewable vitamins. If we vary from it & give her dog food ( just tried blue buffalo) she starts to have uncontrolled urination. The problem Im having now is she has a rash all over her belly & some of her fur fell out. Could this mean she lacks something in her diet or is it something else? She doesnt,t have fleas, she does have small tumors here and there. She also licks the rash so any of the ointments dont stay on long.. ...
I have a 13 year old short hair border collie beagle mix, fo r2-3 years she has had bladder control issues. Weve been to a few different vets and ran I have a 13 year old short hair border collie beagle mix, fo r2-3 years she has had bladder control issues. Weve been to a few different vets and ran tons of tests, 2years ago one of them said shed only live a month or two. The only thing I found to stop the accidental urination was changing her diet (on my own ) to Cooked grd. Beef, brown rice & green beans. We have now supplemented it with chewable vitamins. If we vary from it & give her dog food ( just tried blue buffalo) she starts to have uncontrolled urination. The problem Im having now is she has a rash all over her belly & some of her fur fell out. Could this mean she lacks something in her diet or is it something else? She doesnt,t have fleas, she does have small tumors here and there. She also licks the rash so any of the ointments dont stay on long.. ...
I agree Amboyduke. With the latest Tommy Robinson story of him having a milkshake thrown at him after being assaulted by muslims and their fellow fascists, and the police ignoring his request that then perps be arrested, they are inching closer to civil war. Either that or its capitulation.. The disgusting cops ignored Tommy and one got into a squad car and drove off. Later on the milkshake perp can be seen skiting (showing off) on his phone at 10:45.. https://www.youtube.com/watch?v=7qbwZswFehs. Diversity is a clear fail in the UK.. ...
Breeder of ISDS registered Working Border Collie puppy. Herding instinct, obedience, agility. Border Collie working sheepdogs puppies, slate, lilac Blue Merle and red merle. working sheepdog for dog agility and obedience.
The first of the modern treatments for heart failure lay in the development of assist devices. These paved the way for the development of more complicated mechanisms such as the TAH. These apparatus do not act to take over the action of the heart; rather, they reduce the stress exerted on the heart, allowing it to rest and recover. Development of these devices accelerated in the 1960s and 70s due to complications and mortality associated with early total HTxs.8 The evolution of pump technology brought about two main types of devices: pulsatile LVADs, where blood is pumped through the internal device via an external pump mimicking the action of the heart; and, continuous flow pumps (axial and centrifugal), in which a magnetically controlled rotor forces blood through the device. It should be noted that when a continuous flow pump is implanted the patient will employ an abnormal non-pulsatile state, posing difficulties in clinical measurement of pulse and blood pressure. Both types of devices are ...
Goserelin (INN, USAN, BAN), or goserelin acetate, sold under the brand name Zoladex (by AstraZeneca) among others, is a medication which is used to suppress production of the sex hormones (testosterone and estrogen), particularly in the treatment of breast and prostate cancer. It is an injectable gonadotropin releasing hormone superagonist (GnRH agonist), also known as a luteinizing hormone releasing hormone (LHRH) agonist. Structurally, it is a decapeptide. It is the natural LHRH/GnRH decapeptide with two substitutions to inhibit rapid degradation. Goserelin acetate stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner. This causes the disruption of the endogenous hormonal feedback systems, resulting in the down-regulation of testosterone and estrogen production. Zoladex was approved by the U.S. Food and Drug Administration in 1989 for treatment of prostate cancer. Goserelin acetate is used to treat hormone-sensitive cancers of the ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
The Bearded Collie Dog Breed (also known as Beardie (nickname), Highland Collie, Mountain Collie, Hairy Moued Collie, Argle Bargle) Information and Facts, including buying advice, photos, average costs to own and health care tips.
Bearded Collie - Records dating back to the 16th century show that Polish Lowland Sheepdogs were brought into Scotland, and its believed that they were crossed with local farm collies to create the breed now known as the Bearded Collie.
Even if 40 or 50 thousand years were too short a time for the evolutionary development of a truly new and highly complex mental adaptation, which is by no means certain, it is certainly long enough for some groups to lose such an adaptation, for some groups to develop a highly exaggerated version of an adaptation, or for changes in the triggers or timing of that adaptation to evolve. That is what we see in domesticated dogs, for example, who have entirely lost certain key behavioral adaptations of wolves such as paternal investment. Other wolf behaviors have been exaggerated or distorted. A border collies herding is recognizably derived from wolf behaviors, as is a terriers aggressiveness, but this hardly means that collies, wolves, and terriers are all the same. Paternal investment may be particularly fragile and easily lost in mammals, because parental investment via internal gestation and lactation is engineered into females but not males. ...
Hi, Im Lesley aka Moogsmum. After years of dreaming about it Ive finally set up my own business making and selling my handmade bags, brooches, pictures and accessories. I love to sew, knit, crochet, spin and weave. Married to Mr Moog with two lovely teenagers and two wonderful dogs - Merlin Moog, the worlds cuddliest border collie, and naughty collie x spaniel Willow Wobbler. You can often find me on Instagram where Im @mrs_moog and I blog here about my crafty doings and life stuff ...
By Carol Bryant, FIDO Friendly magazine. "When our 14-year-old Border Collie Natasha was put down after a long battle with chron-ic kidney failure, it was one of the most traumatic events Id ever faced," writer and dog mom Joanne Brokaw shared.. For those of us who have loved and lost a dog, we relate to those words and the accompanying grief that becomes a part of our fiber forever. Brokaw and her husband opted to bury Natasha near the pond where she loved to swim. Brokaw recalled the sun shining, the trees whispering, and time to reflect and say goodbye to her be-loved dog.. Preparing for the passing of our fur-ry friends is but one part of the grieving process; for many, understanding the options available and how to best memorialize Fido are heavy considerations.. Funeral homes provide an important service in letting people say goodbye and honor the life of a beloved pet. Brokaw learned of Harris Funeral Home in Rochester, New York, which opened the Pets at Peace Chapel. Owner Mike Harris ...
So - a bit about me. Im living in Sydney at the moment, having returned from some time overseas just under 2 years ago. Im a mature, single female, Im easy going and respectful of others privacy and have great rental and professional/personal references. I am an Australian Citizen of UK birth. I am sociable, happy to share a glass of wine, and the occasional meal, but Im not looking for a party house. If I do share (Im also looking for a granny flat style accommodation) then I prefer to only share with one or two others at the most. I love living near nature, so a city house is not what Im looking for.. I have two very well behaved pets - a cat called Kitwe (who is a very lazy neutered boy, sleeping most of the day and night away) and a beautiful (small) border collie called Mr Finn. Both are rescues and I actually brought Mr Finn back with me from South Africa (my cat is Australian and went with me to SA and came home again). They are both neutered and I keep them well groomed and clean. ...
This blog is dedicated to the memory of my beautiful girl Destiny. She was an American Eskimo / Border Collie mix. She had been diagnosed with Chronic Renal Failure (CRF) in April of 2008, but had tenacity and a strong will and a love for life.... I thought perhaps sharing my story would help other 4-legged friends and DogMas who have gone through the same struggles, heartache, and never ending love and adoration.. ...
Paul Keil and Greg Downey Paul, the lead author, interviewed sheepdog trialer Damian Wilson about his interactions with his dog, a border collie named Yandarra Whiskey. Damian and Whiskey gave Paul a demonstration of ...
Ive read these laws several times and I see no mention in them about coyote hybrids, coydogs, coyote-dog-mixes, or any other such terms. So, Im wondering if this means there is a loophole for coydogs as well, perhaps even high content coydogs, as long as I can prove the animal is part dog, which given that coyotes and dogs are actually different species and have different DNA, getting a DNA test, should be able to prove. On the other hand, people could claim pure coyote even if not, so maybe a midcontent or low content coyote mix that has more visibly doggy traits would be better. However, the only coydog breeder I know of that actually bred by contents was Sundance Ranch and they stopped breeding. Now, I only know of that lady who breeds her border collie to a coydog mix and the puppies dont look very coyote-like, but I guess in way, that would actually be good, since then nobody could claim pure coyote since the animal would have markings like a border-collie ...
What About His Medications? : A true, personal story from the experience, I My Dog Died. My border collie died a few days ago. He was 14 years old and had a heart murmur. I have rymadil, laysix and some other meds that I dont know what to do with. I dont want to throw them out. Did a...
As my dog, Whizz, is featured in Peters case study notes, and as, in his opinion, Whizz shouldnt have done agility Id just like to state the actions that I took that helped me arrive at the decision to do agility with Whizz.. Whizz was my first Border Collie. I bought him as a pet and also with obedience and agility in mind. When Whizz was about eight months old I noticed that when he was lying down he stood up slightly strangely. Instead of leaping to his feet he sat up first, then stood. It wasnt something really noticeable and he wasnt lame when he got up, but I just thought Id like to have it checked out.. I took him to the vet who advised an x-ray. When this was done the vet told me that he didnt have great hips. I was pretty upset and asked what I should do in terms of the obedience and agility career I had in mind for him. I was referred to the RVC and saw one of the specialists there, who is still the chief scrutinizer of the BVA hip scoring scheme. He looked at Whizzs x-rays and ...
Hi! Susan and Scott here! We are on a journey together to discover the mysteries of life. Susan is into her second career as a holistic health practitioner and teacher, after retiring from public school education. Scott is a golf course superintendent at a high profile private country club outside of Philadelphia. We have two wonderful teenage daughters, a border collie, and an extremely independent cat. Our interests include alternative healing, dowsing, earth energy work, holistic living, and having fun. We have stumbled upon this path as a result of a number of "co-incidences" both together and separately. So basically that is the long and short of it…well, sort of, they only give us a really small amount of character strokes to get this written up in…so to sum it up… Life….It is a wonderful, adventurous journey, filled with unlimited opportunities and possibilities!! So we are just wondering…. how is your adventure going ...
Hi! Susan and Scott here! We are on a journey together to discover the mysteries of life. Susan is into her second career as a holistic health practitioner and teacher, after retiring from public school education. Scott is a golf course superintendent at a high profile private country club outside of Philadelphia. We have two wonderful teenage daughters, a border collie, and an extremely independent cat. Our interests include alternative healing, dowsing, earth energy work, holistic living, and having fun. We have stumbled upon this path as a result of a number of "co-incidences" both together and separately. So basically that is the long and short of it…well, sort of, they only give us a really small amount of character strokes to get this written up in…so to sum it up… Life….It is a wonderful, adventurous journey, filled with unlimited opportunities and possibilities!! So we are just wondering…. how is your adventure going ...
Border Collies entered our lives 16 yrs. ago when I received Riorun Jet from Patrick Shannahan. Jet is my soul mate, a talented trick dog, master agility dog, and open sheepdog. He is intense when he is working and mellow when he is not. Jet has placed in USBCHA open competition only working sheep a couple of times a week. It can be done. Kilt came to us from Diana Gauthier (Keen-Eye stockdogs) in Canada. Kilt is a ton of fun and is all business about working livestock. She has placed in open competition and is getting better about teaming up with me. We won our first open class (2011) with a marked shed, pen, single this year. We have bred only one litter by Jet. I kept a pup, Walk-Up Yoko. She is extremely talented in agility and can hold her own on sheep, too. She qualified for the National Nursery finals and has placed well in pro-novice along with winning several open classes in her later years ...
STUART, Fla. - A Florida man was delighted when his dog returned five days after running away during a thunderstorm - but then he noticed that someone had sliced open the border collies back. Dr.
A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions ...
TY - JOUR. T1 - Targeted PCR Array Analysis of Genes in Innate Immunity and Glucocorticoid Signaling Pathways in Mice Cochleae Following Acoustic Trauma. AU - Maeda, Yukihide. AU - Kariya, Shin. AU - Omichi, Ryotaro. AU - Noda, Yohei. AU - Sugaya, Akiko. AU - Fujimoto, Shohei. AU - Nishizaki, Kazunori. PY - 2018/8/1. Y1 - 2018/8/1. N2 - Aim: To comprehensively analyze cochlear gene expressions related to innate immunity and glucocorticoid signaling at onset of acute noise-induced hearing loss (NIHL). Background: Recent studies suggested innate immunity is involved in the cochlear pathology of NIHL. Glucocorticoids may modulate immune actions in cochleae. Methods: Mice were exposed to 120 dB-octave band noise for 2 hours. Twelve hours later, a targeted PCR array analyzed cochlear expressions of 84 key genes in inflammation and immune pathways and 84 genes in the glucocorticoid signaling pathway. Real-time RT-PCR was used to analyze expression of two immune-related genes, Ccl12 and Glycam1, in ...
A lot of hurdles stood in the way between growing grapes and distilling a Maywood-quality wine. To begin with, Vitex vinifera is not ideally suited to growing in Connecticut. Prone to powdery mildew and marginally hardy here, there were challenges-and Japanese beetles were among the major stumbling blocks. Deer and wild turkeys were also an issue. A grape cluster requires 15 leaf clusters to ripen. Unlike most plants, when a grape leaf is marred by nibbling insects or predators, the plant no longer benefits from its photosynthesizing input and the grape cluster does not receive the oomph it needs to ripen. Within the organic realm, Bollard selected solutions that include beneficial nematodes for Japanese beetle larvae and border collies to chase off turkeys and deer. Alas, the oldest border collie of the original ultra-efficient crew recently passed away. Maywood might be relying on netting for its grapes this coming season while replacements are trained.. ...
Progressive hearing loss is a common disorder that appears to arise from a diverse range of genetic mechanisms, probably reflecting the anatomical and functional complexity of the human ear. Two studies of mice and humans with hearing loss have converged on a pathogenic mutation that is distinct from the 50 previously characterized mutations in that it affects a small regulatory RNA rather than a protein-coding gene.. In a genetic screen for hearing-impaired mice, Lewis et al. identified a mutation that, when present in heterozygous form, caused abnormalities of inner and outer hair cells [sensory receptors in the ear that are critical for hearing; wild-type (left) and heterozygous (right) inner cells are shown above] and progressive hearing loss beginning when the mice were 4 to 6 weeks old. The mutation resides within the functional "seed" region of a microRNA called miR-96 that is expressed in hair cells and that, like other microRNAs, is presumed to bind to and alter the expression of ...
Collies share Collie Eye Anomaly (CEA) with several other breeds it s not just a problem for collies. CEA is more technically known as Choroidal Hypoplasia (CH). It is a recessively inherited eye disorder that causes abnormal development of the choroid - an important layer of tissue under the retina of the eye. This disease is seen most frequently in U.S. collies, but also worldwide in Rough and Smooth Collies, Border Collies, Australian Shepherds, Lancashire Heelers, and Shetland Sheepdogs. Since the choroid layer does not develop normally from the start, the primary abnormality can be diagnosed at a very young age. Regrettably, there is no treatment or cure for CEA. ...
Collies share Collie Eye Anomaly (CEA) with several other breeds it s not just a problem for collies. CEA is more technically known as Choroidal Hypoplasia (CH). It is a recessively inherited eye disorder that causes abnormal development of the choroid - an important layer of tissue under the retina of the eye. This disease is seen most frequently in U.S. collies, but also worldwide in Rough and Smooth Collies, Border Collies, Australian Shepherds, Lancashire Heelers, and Shetland Sheepdogs. Since the choroid layer does not develop normally from the start, the primary abnormality can be diagnosed at a very young age. Regrettably, there is no treatment or cure for CEA. ...
I moved to Lethbridge from Thunder Bay, Ont. in October 2007. I have been involved with dogs all my life. I was a dog groomer for 30 years, 15 of those I was self employed. I retired from grooming in October 2007. Collies are my love and I could never imagine owning another breed..... However, I have fallen in love with Flatcoated Retrievers !!! This blog will mostly be about my family, my collie Tate, my collie Kort, who joined the family on June 29 2008 & Lync, a flatcoated Retriever who joined the family on December 15 2013 :) Sadly Tate passed away on November 3rd 2014, we miss him terribly :( but with the end of life comes new life, and it is with great joy I would like to announce the addition of a new Tri Colour Collie to our home, thankful for the generosity of a very special friend, Ash came to live with us on March 5, 2015 ! :) So begins a new Chapter ...
I moved to Lethbridge from Thunder Bay, Ont. in October 2007. I have been involved with dogs all my life. I was a dog groomer for 30 years, 15 of those I was self employed. I retired from grooming in October 2007. Collies are my love and I could never imagine owning another breed..... However, I have fallen in love with Flatcoated Retrievers !!! This blog will mostly be about my family, my collie Tate, my collie Kort, who joined the family on June 29 2008 & Lync, a flatcoated Retriever who joined the family on December 15 2013 :) Sadly Tate passed away on November 3rd 2014, we miss him terribly :( but with the end of life comes new life, and it is with great joy I would like to announce the addition of a new Tri Colour Collie to our home, thankful for the generosity of a very special friend, Ash came to live with us on March 5, 2015 ! :) So begins a new Chapter ...
Normal: This is what collie breeders hope to produce, a "normal-eyed" collie puppy with no CEA. A "Normal" eye rating is the best rating. There are also "Go Normals", which are so mildly affected at a young age, that later, the pale areas caused by choroidal hypoplasia disappear, leading to what is termed a "Go Normal." These "go normal" puppies are still affected with CEA, and can pass CEA onto their future offspring. The only way to be certain a collie is not a carrier of CEA is through genetic testing. Also, dogs coat color can make it difficult to get 100% accurate results, as the pigment in a Blue Merles eyes can be diluted along with his coat color ...
Normal: This is what collie breeders hope to produce, a "normal-eyed" collie puppy with no CEA. A "Normal" eye rating is the best rating. There are also "Go Normals", which are so mildly affected at a young age, that later, the pale areas caused by choroidal hypoplasia disappear, leading to what is termed a "Go Normal." These "go normal" puppies are still affected with CEA, and can pass CEA onto their future offspring. The only way to be certain a collie is not a carrier of CEA is through genetic testing. Also, dogs coat color can make it difficult to get 100% accurate results, as the pigment in a Blue Merles eyes can be diluted along with his coat color ...
Collies rough, Austria, CEA free, MDR1 free, DM free, all colours, puppies for sale, Deckrüde, Colliewelpen zu verkaufen, sable, Showerfolge, Top Collie Europe 2016, UK, Amerika, Kinderhund, Champion
It has been one year since both of my best friends died. ~Kris (Belladaze) Loyal Teddy, my retriever/border collie passed quietly at age 16. Sweet huge Ali, my 12 year old mastiff/lab mix, suffered a horrible (but quick) death 10 evenings later after a head-over-heels tumble during a routine evening garden wild bunny chase. Alis…
The 2017 Oregon legislative session begins two weeks from tomorrow, on Wednesday, February 1. Already, there are lots of proposed payments, measures and resolutions posted on the legislatures web site, starting from marquee payments to deal with the state finances shortfall and its gun registry loopholes, to resolutions naming an official state horse (the Kiger Mustang) and a canine (the Border Collie). For our trustworthy readers, theres additionally a beneficiant serving to of hashish payments. We rely 28 of them.. Again in October, we wrote that points surrounding public consumption, like hashish cafés and particular occasion (short-term) licenses, can be up for dialogue. As proven under, that has confirmed to be true. We have now additionally written again and again (and repeatedly) about the necessity to merge Oregons medical and leisure marijuana packages. That seems to be up for critical consideration as nicely. Lastly, weve got written concerning the states burgeoning industrial ...
Reed is a 7 month old purebred BC that can be best described as a velcro dog! He has been fully vetted and neutered, loves to play with other dogs and adores children. Reed has had little training but is responding well to basic commands with the help of hotdog bites! Reed will be a fairly active dog, and would make a great frisbee, ball, flyball, and/or agility dog.. Reed does not have any issues or emotional scars whatsoever, he just hasnt been taught what to do, and has been lacking an alpha to show him the way! Hes learning the ropes at our Border Collie Boot Camp and is waiting for a forever home.. Reed was adopted, and much to our surprise, at only 7 months of age, he tested positive for HW. This changed my protocol in rescue forever. Now, all dogs from 6 months of age are tested for HW disease. Reed did undergo the immiticide treatment and is HW negative today. ...
My name is Kathy. I have 3 grown children, 3 grandchildren,a Border Collie, named Buddy and a tuxedo cat, named Carter. I had lived all my life in Southern California until moving to the Sacramento area 2 years ago. I have my degree in nutrition and have an interest in the health of animals as well as humans ...
But I so want one of these sheep mowers that are being featured at this years Wired NextFest. So adorable. (And, if youve got border collies in the neighborhood, you get the added excitement of watching the dogs try to corral them.). Also, if youre in the Chicago area between September 27 and October 12, do check out NextFest. We went a couple of years ago and it was really interesting. (And Im not just saying that because they had the cloned cats there and I go all squishy over any event that features kitties.) Besides, its free and while youre there, you can check out the rest of Millennium Park. Dont forget to take the obligatory shot of yourself reflected in the Bean.. (Thanks to coworker Jason for the linkage.). ...
I have a Border Collie, Red healer Cross: Female 8 yrs, in very good health on natural food diet and not over weight. Problem: deteriorating and painful
Thats wReggie with a silent "W" like Wrangler, wrench, write and wrong, and now new and improved with a lower case "w" with all the cutting edge sophistication of eBay or iPhone. Some words need a "W" like "one". Whats that about? I love to travel and observe the world. I married my teenage sweetheart who is still my first wife. I guess you can call me an animal lover too with 4 border collies, 3 horses, two cats, 21 chickens and one Brine Shrimp. I have a deep love and respect for bacon and club sandwiches and take convenience of gravity for granted. Finally, I love to laugh ...
Border Collies entered our lives 16 yrs. ago when I received Riorun Jet from Patrick Shannahan. Jet is my soul mate, a talented trick dog, master agility dog, and open sheepdog. He is intense when he is working and mellow when he is not. Jet has placed in USBCHA open competition only working sheep a couple of times a week. It can be done. Kilt came to us from Diana Gauthier (Keen-Eye stockdogs) in Canada. Kilt is a ton of fun and is all business about working livestock. She has placed in open competition and is getting better about teaming up with me. We won our first open class (2011) with a marked shed, pen, single this year. We have bred only one litter by Jet. I kept a pup, Walk-Up Yoko. She is extremely talented in agility and can hold her own on sheep, too. She qualified for the National Nursery finals and has placed well in pro-novice along with winning several open classes in her later years ...
So. I played through The Last Guardian. As you might expect from someone with two Team ICO tattoos, I have some thoughts.. I have a dog, a Border Collie, named Murphy. Murphy and I understand each other better than any other dog Ive previously lived with, whether because of his breed or the time we spent doing agility together or just because were a good personality match. Working with Murphy is not like training a dog. It is more like trying to bridge a communicative gap with an alien intelligence who desperately wants to please, depending on his mood that day and whether or not hes mad at me for some perceived personal slight. It doesnt feel that hes less intelligent, really-its just that his world is completely different from mine. He might as well be from a planet made of synesthesia.. Fumito Ueda has managed to convey that unique relationship to an almost spooky degree in The Last Guardian. Ive already seen complaints from reviewers about your giant cat-bird-wolf being stubborn or ...
Thats wReggie with a silent "W" like Wrangler, wrench, write and wrong, and now new and improved with a lower case "w" with all the cutting edge sophistication of eBay or iPhone. Some words need a "W" like "one". Whats that about? I love to travel and observe the world. I married my teenage sweetheart who is still my first wife. I guess you can call me an animal lover too with 4 border collies, 3 horses, two cats, 21 chickens and one Brine Shrimp. I have a deep love and respect for bacon and club sandwiches and take convenience of gravity for granted. Finally, I love to laugh ...
Hello to all, I have a 1 1/2 year old border collie/blue heeler/rat terrier mix. She sometimes seems to love agility, her tail wags and she flies...
Pumpkin was an affectionate nickname in my family, so I chose it as the name for my 1st Border Collie. I love the word Pumpkin-how it fills my mouth and suggests the shape of the fruit. Yes, a pumpkin is a fruit- actually a berry. It is a member of the Cucurbitaceae family, along with melons…
I am a stay-at-home mom. I have been married to my handsome and wonderful husband for over 14 years. Right now hes battling stomach/esophagus cancer. So I do my best to craft when I can. I have two wonderful boys. My oldest, Garett, is 24 and served 5 years in the Navy. Hes been home since the beginning of the year (2014). We are very proud of him. My youngest, "DJ", is 13 and in the 8th grade. I have two Border Collie mix dogs (Koda and Rugu), one Calico cat (Hydie), one orange Tabby cat (Bosley), one Tea Cup Chihuahua (Gigi...I LOVE her sooo much), a Chiweinnie (Lily....sweetest dog ever), and a Jack Russell/Chihuahua (Connor....AAALL boy ...
You may find this publication the answer to your problems. Brain Research Protocols Volume 6, Issue 3, February 2001, Pages 159-166 Cryoembedding and sectioning of cochleas for immunocytochemistry and in situ hybridization Donna S. Whitlon, Renee Szakaly, Mary A. Greiner Abstract Current emphasis on biochemical and molecular aspects of cochlear anatomy underscores the necessity for high quality cryostat sections of the inner ear. The large volume of fluid space within the cochlea makes cryoembedding and sectioning of the organ more problematic than that of other, more homogeneous tissues. Our method for cryoembedding of cochleas for immunocytochemistry and in situ hybridization uses slow infiltration with increasing concentrations of sucrose followed by degassed embedding medium before final orientation and freezing. This method permits high quality cryosections to be cut which preserve overall structure and cellular resolution. Author Keywords: Cryosections; Cochlea; Immunocytochemistry; In ...
HeartCare is one of Western Australias largest providers of cardiac care, offering the widest network of clinics across metropolitan and regional WA. We provide a comprehensive service that includes consultation, cardiac testing and invasive procedures
My foster mom has introduced me to a lot of people, young and old. I enjoy being around humans of all ages however kids tend to arouse me while they are running around playing. Unfortunately I have to ask for a home with no children. My instincts tell me to control their behavior with herding and nipping. Learning self control is on my to-do list. The doctor says I have a mild case of Bells Palsy. It makes my face droop slightly on one side. I can still run fast after my balls ( I love playing fetch!). Bells Palsy is cosmetic only and has no impact on my quality of life. Theres no special care needed other than a requirement for "love". I was also recently diagnosed with Autoimmune Thyroiditis, which is an hereditary thyroid disease. It is controlled with an inexpensive medication and it requires annual blood testing to assure my medication is at optimal dosage. ...
Information regarding Pug dog eyes and eye problems. Proper care. Diseases: Symptoms, diagnosis, treatment and prevention. Once you suspect that your dog is suffering from any of these diseases, veterinary check up is needed to prevent more serious problem and losing your Puggles. Pugs, and now Puggles, may develop eye problems as they age. So, the first step in avoiding eye problems is an obvious one. Bathing should be done every month. This is a condition where the actual tear duct gland becomes infected and inflamed and in some instances it may even fall out of place. Families with children, singles, seniors, apartments, houses with yards Temperament: Select a Tag anxiety basic dog obedience Basset Hound Training Basset Hounds Beagle Puppy Training Beagle Training Beagles Bichon Frise Bichon Frise Training Border Collie Border Collie obedience Border Collie Training Boston Terrier Boston Terrier Training Boxer Boxer Dog boxer dog training bulldog canine aggression Cavalier King Charles ...
A 13-day-old baby, born of a full term, uncomplicated, normal vaginal delivery at a primary healthcare centre presented with severe bilateral proptosis. At 12 h postpartum a presumed subconjunctival haemorrhage was seen on the temporal aspect of the right eye following which bilateral, rapid onset, painless proptosis developed.. At presentation in the department of ophthalmology CSMMU Lucknow, the child had bilateral, severe, axial, non-pulsatile, almost symmetrical proptosis, along with forniceal prolapse, conjunctival chemosis and exposure keratopathy. The ocular movements were restricted in all directions in both the eyes. There was no fundal view because of the severe exposure keratopathy (figure 1A). The systemic examination was normal and no evidence of bleeding diathesis or battering was found. ...
adopting seniors (12) adoption (39) Afghan (3) African Wild Dog (1) agility (6) Airedale Terrier (4) American Foxhounds (1) American Staffordshire Terrier (1) anxiety (1) APBT (1) Appenzeller Sennenhunde (1) Australian Shepherd (2) BARF (1) barking (2) Basenji (1) Basset (4) beagle (16) Bearded Collie (2) Beauceron (1) Bedlington (1) Belgian Shepherd (1) bench trial (2) Berger Picard (1) Bernese Mountain Dog (2) Bichon Frise (1) black and tan (1) Black Russian Terrier (1) Bloodhound (2) blue tick (3) boarder collie (1) Border Collie (8) Border Terrier (1) borzoi (4) Boston Terrier (3) Bouvier des Flandres (1) Boxer (10) brachycephalic breeds (1) breed specific rescue (2) Briard (1) Broholmer (1) Bull Dog (5) Bull Mastiff (3) Bull Terriers (8) Bullmastiff (1) Cairn (1) Cane Corso (1) Cardigan Welsh Corgi (2) Carolina Dog (1) cats (7) cats and dogs (2) Caucasian Ovcharka (1) Cavalier King Charles Spaniel (3) Chesapeake Bay Retriver (1) Chihuahua (28) children with pets (4) Chinese Crested (1) ...

Refsum disease - WikipediaRefsum disease - Wikipedia

Nogueira, C.; Meehan, T. & ODonoghue, G. (2014). "Refsums Disease and Cochlear Implantation". Annals of Otology, Rhinology, ... Adult Refsum disease may be divided into the adult Refsum disease 1 and adult Refsum disease 2 subtypes. The former stems from ... Refsum disease. Other names. Adult Refsum disease, heredopathia atactica polyneuritiformis, phytanic acid oxidase deficiency ... Refsum disease is an autosomal recessive[5] neurological disease that results in the over-accumulation of phytanic acid in ...
more infohttps://en.m.wikipedia.org/wiki/Refsum_disease

Otolaryngology | Rhinology | Otolaryngology and Rhinology | Open Access Journals | Research, Study, Papers | JSciMed CentralOtolaryngology | Rhinology | Otolaryngology and Rhinology | Open Access Journals | Research, Study, Papers | JSciMed Central

Spontaneous Intra-Cochlear Hemorrhage Leading to Sensorineural Hearing Loss. Miranda Morrison, Nils Guinand, Angeliki Alianou, ... Conclusion: Hematological diseases often have a clinical presentation with signs and symptoms of the otorhinolaryngological ... and an MRI compatible with acute intra-cochlear hemorrhage. Spontaneous intra-labyrinthine bleeding is a rare cause of SNHL. ...
more infohttps://www.jscimedcentral.com/Otolaryngology/vol4issue1.php

UC Davis Health | Department of Otolaryngology | Pediatric OtolaryngologyUC Davis Health | Department of Otolaryngology | Pediatric Otolaryngology

She specializes in airway management, hearing loss and chronic ear disease, tumors and cysts of the head and neck, and speech ... Services provided include specialized testing and fitting and programming hearing aids and cochlear implants. ...
more infohttp://www.ucdmc.ucdavis.edu/otolaryngology/specialty/pediatric-otolaryngology/index.html

Cochlear Implantation in Ménières Disease | Vestibular Disorders AssociationCochlear Implantation in Ménière's Disease | Vestibular Disorders Association

Menieres disease will have the similar hearing improvements with cochlear implants as CI patients without Menieres disease. ... A study to determine if patients with Menieres disease will have the similar hearing improvements with cochlear implants as CI ... Importance Though the effects of cochlear implantation (CI) on patients with hearing loss has been well described, its effect ... on the auditory and vestibular symptoms in patients with Ménières disease (MD) has not been firmly established. ...
more infohttp://vestibular.org/news/05-02-2014/cochlear-implantation-m%C3%A9ni%C3%A8re%E2%80%99s-disease

Cochlear Implantation in Charcot-Marie-Tooth Disease: Case Report and Review of the LiteratureCochlear Implantation in Charcot-Marie-Tooth Disease: Case Report and Review of the Literature

... on CNC phoneme testing in the cochlear implant-only condition. ,i,Conclusion,/i,. We report the third case of cochlear ... Left-sided cochlear implantation was performed using a conventional length lateral wall electrode. Intraoperative device ... SNHL in CMT is hypothesized to result from disruption of synchronous activity of the cochlear nerve. In patients with CMT, ... Our results corroborate two earlier reports that cochlear implantation is a viable option for rehabilitation of SNHL in this ...
more infohttps://www.hindawi.com/journals/crim/2018/1760978/

Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant - Volume 18, Number 6-June 2012 -...Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant - Volume 18, Number 6-June 2012 -...

Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People Centers for Disease Control ... Rubin LG, Papsin B; Committee on Infectious Diseases and Section on Otolaryngology-Head and Neck Surgery. Cochlear implants in ... Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant. Emerging Infectious Diseases. 2012; ... Reefhuis J, Honein MA, Whitney CG, Chamany S, Mann EA, Biernath KR, Risk of bacterial meningitis in children with cochlear ...
more infohttps://wwwnc.cdc.gov/eid/article/18/6/11-0906_article

Table - Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant - Volume 18, Number 6-June...Table - Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant - Volume 18, Number 6-June...

Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People Centers for Disease Control ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant Elaine Stanford, Shamez Ladhani. , ... Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant. ...
more infohttps://wwwnc.cdc.gov/eid/article/18/6/11-0906-t1.htm

Relative Efficiency of Cochlear Hydrops Analysis Masking Procedure and Cervical Vestibular Evoked Myogenic Potential in...Relative Efficiency of Cochlear Hydrops Analysis Masking Procedure and Cervical Vestibular Evoked Myogenic Potential in...

Hence the present study aimed to compare the efficiency of cVEMP and CHAMP in evaluating Menieres disease. The study included ... Relative Efficiency of Cochlear Hydrops Analysis Masking Procedure and Cervical Vestibular Evoked Myogenic Potential in ... However none of the previous reports have compared the two tests for their relative efficacy in identifying Menieres disease. ... Cervical vestibular evoked myogenic potential (cVEMP) and cochlear hydrops analysis masking procedure (CHAMP) have both shown ...
more infohttps://www.hindawi.com/journals/aoto/2015/978161/abs/

Auditory brainstem implant in bilateral and completely ossified cochleae. | CureHunterAuditory brainstem implant in bilateral and completely ossified cochleae. | CureHunter

Cochlear Diseases (physiopathology, rehabilitation) *Cochlear Implantation (methods) *Deafness (physiopathology, rehabilitation ... Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find ... Magnetic resonance imaging confirmed the diagnosis by showing no cochlear signal on T2-weighed images and ruled out brainstem ... Pure tone audiometry, auditory brainstem response tests, and promontory tests did not reveal any cochlear activity. Computed ...
more infohttp://www.curehunter.com/public/pubmed12544033.do

Piebald Trait disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsPiebald Trait disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

cochlear disease 10.3. MITF PAX3 SNAI2 34. childhood kidney cell carcinoma 10.3. MITF PAX3 ... Global: Genetic diseases Rare diseases Anatomical: Eye diseases Skin diseases See all MalaCards categories (disease lists) ... The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ... Screening Protocol for Genetic Diseases of Allergic Inflammation. Recruiting. NCT00852943 6. Natural History of Diseases ...
more infohttps://www.malacards.org/card/piebald_trait?search=

Exploring Voluntary Control of TinnitusExploring Voluntary Control of Tinnitus

Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; ... Alzheimers Disease Of all the types of Dementia, Alzheimers disease is the most common, affecting around 465,000 people in ... Meniere Disease. A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; ... The COCHLEAR NERVE is typically spared and HEARING LOSS and TINNITUS do not usually occur. Symptoms usually resolve over a ...
more infohttps://www.bioportfolio.com/resources/trial/72963/Exploring-Voluntary-Control-of-Tinnitus.html

Clinical Trial of Transcranial Magnetic Stimulation for Relief of TinnitusClinical Trial of Transcranial Magnetic Stimulation for Relief of Tinnitus

Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; ... Alzheimers Disease Of all the types of Dementia, Alzheimers disease is the most common, affecting around 465,000 people in ... Home » Topics » Alzheimers Disease » Research » Clinical Trial of Transcranial Magnetic Stimulation for Relief of Tinnitus ... Infectious Diseases Mental Health Neurology Obstetrics Orthopedics Public Health Respiratory Rheumatology Urology Track topics ...
more infohttps://www.bioportfolio.com/resources/trial/65994/Clinical-Trial-of-Transcranial-Magnetic-Stimulation-for-Relief-of-Tinnitus.html

NIOSHTIC-2 Search Results - Basic ViewNIOSHTIC-2 Search Results - Basic View

Functional changes in central auditory pathways resulting from cochlear diseases. Authors. Salvi-RJ; Henderson-D; Boettcher-FA ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People Centers for Disease Control ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, ...
more infohttp://www2.cdc.gov/nioshtic-2/BuildQyr.asp?s1=Hearing%2A&f1=%2A&s2=&PageNo=1523&RecNo=1523&View=b&

NIOSHTIC-2 Search Results - Basic ViewNIOSHTIC-2 Search Results - Basic View

Functional changes in central auditory pathways resulting from cochlear diseases. Authors. Salvi-RJ; Henderson-D; Boettcher-FA ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People Centers for Disease Control ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, ...
more infohttp://www2.cdc.gov/nioshtic-2/BuildQyr.asp?s1=%27hearing+loss%27&f1=%2A&Startyear=&t1=0&s2=noise%2A&terms=3&Adv=1&ct=&B1=Search&f2=%2A&Limit=500&Sort=DP+DESC&D1=10&EndYear=&PageNo=1033&RecNo=1033&View=b&

Hearing Loss Help - Forums and Discussions - MedHelpHearing Loss Help - Forums and Discussions - MedHelp

Looking For More Info on Sporadic Hearing Loss/Possibly Cochlear Menieres Disease dsg1211 ... cochlear implants, culturally deaf, hearing aids, hearing dogs, home safety, Menieres disease, oral communication, safety, ... I was diagnosed yesterday,after only one visit, with menieres disease. Ive been miserable for the last five weeks. Dizzy, ... condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or ...
more infohttps://medhelp.org/forums/Hearing-Loss/show/177

SelfDecode | Genome AnalysisSelfDecode | Genome Analysis

Cochlear Diseases PCDH15. Constipation OPRM1. Costeff Optic Atrophy Syndrome OPA3. Coxsackievirus Infections SLC22A5. ... Parkinsons Disease ATP13A2,DRD1,DRD2,PARK2,SLC18A2,SLC6A3,SOD1,SOD2. Anxiety Disorder ADORA2A,APP,CHRNB2,DRD2,MECP2,NPY1R, ... Nervous System Diseases CHRNA4,PENK,SCN8A,SELENOP,SLC18A2,SLC6A3,SOD1. Attention Deficit Hyperactivity Disorder CHRNA4,CHRNB2, ... Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia VCP. ...
more infohttps://www.selfdecode.com/molecular-function/GO:0007626/

FusionGDB: Fusion Gene annotation DataBase - SearchFusionGDB: Fusion Gene annotation DataBase - Search

Cochlear Diseases. 1. CTD_human. Tgene. MPV17. C0017668. Focal glomerulosclerosis. 1. CTD_human. ... Mitochondrial Diseases. 1. CTD_human. Copyright 2018-Present -The University of Texas Health Science Center at Houston ( ...
more infohttps://ccsm.uth.edu/FusionGDB/gene_search_result.cgi?page=page&type=quick_search&quick_search=18099

TargetsTargets

Cochlear Diseases. 1 , 2 Cone dystrophy. 1 , 59 Congenital heart defects, hamartomas of tongue, and polysyndactyly. 1 , 1 ...
more infohttps://pharos.nih.gov/idg/targets?facet=Compartment+GO+Term/Kinocilium

ringing ears - Postsringing ears - Posts

I was recently diagnosed with Menieres disease (cochlear hydrops). My symptoms started af... ... condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or ...
more infohttp://www.medhelp.org/tags/show/14730/ringing-ears?section=subjects

ringing ears - Symptoms, Treatments and Resources for ringing earsringing ears - Symptoms, Treatments and Resources for ringing ears

I was recently diagnosed with Menieres disease (cochlear hydrops). My symptoms started af... ... condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or ...
more infohttp://www.medhelp.org/tags/show/14730/ringing-ears

Table - Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant - Volume 18, Number 6-June...Table - Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant - Volume 18, Number 6-June...

Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People Centers for Disease Control ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant Elaine Stanford, Shamez Ladhani. , ... Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant. ...
more infohttps://wwwnc-origin.cdc.gov/eid/article/18/6/11-0906-t1

Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant - Volume 18, Number 6-June 2012 -...Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant - Volume 18, Number 6-June 2012 -...

Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People Centers for Disease Control ... Rubin LG, Papsin B; Committee on Infectious Diseases and Section on Otolaryngology-Head and Neck Surgery. Cochlear implants in ... Pneumococcal Serotype-specific Unresponsiveness in Vaccinated Child with Cochlear Implant. Emerging Infectious Diseases. 2012; ... Reefhuis J, Honein MA, Whitney CG, Chamany S, Mann EA, Biernath KR, Risk of bacterial meningitis in children with cochlear ...
more infohttps://wwwnc-origin.cdc.gov/eid/article/18/6/11-0906

Cleocin: A Medical Dictionary, Bibliography, And Annotated by Icon Health Publications - ANNE ALMASY Book ArchiveCleocin: A Medical Dictionary, Bibliography, And Annotated by Icon Health Publications - ANNE ALMASY Book Archive

Tinnitus may occur as a manifestation of cochlear diseases; vestibulocochlear nerve diseases; intracranial hypertension; ... EU] Veterinary Medicine: The medical science concerned with the prevention, diagnosis, and treatment of diseases in animals. ...
more infohttp://annealmasy.com/pdf/cleocin-a-medical-dictionary-bibliography-and-annotated-research-guide-to

TINNITUS | SelfDecode | Genome AnalysisTINNITUS | SelfDecode | Genome Analysis

Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; ...
more infohttps://www.selfdecode.com/disease/tinnitus/

WikiGenes - Cochlear NerveWikiGenes - Cochlear Nerve

Disease relevance of Cochlear Nerve. *In the acoustic ganglion, NGFR mRNA expression begins at E4; at the same time, the first ... Chemical compound and disease context of Cochlear Nerve. *Glutamate (50 mM) and aspartate (50 mM) applied intracochlearly ... Gene context of Cochlear Nerve. *FGF1 and FGF2 act as trophic factors for the developing cochlear nerve fibres [26]. ... High impact information on Cochlear Nerve. *Kainic acid injections result in degeneration of cochlear nucleus cells innervated ...
more infohttps://www.wikigenes.org/e/mesh/e/7542.html
  • Since phytanic acid is not endogenously produced in the human body, individuals with Refsum disease are commonly placed on a phytanic acid-restricted diet and avoid the consumption of fats from ruminant animals and certain fish, such as tuna, cod, and haddock. (wikipedia.org)
  • Hematological diseases often have a clinical presentation with signs and symptoms of the otorhinolaryngological area. (jscimedcentral.com)
  • Refsum disease is an autosomal recessive neurological disease that results in the over-accumulation of phytanic acid in cells and tissues. (wikipedia.org)
  • The presence of cells in the basal and suprabasal layers of the epidermis containing variably sized vacuoles with accumulated lipids is pathognomonic for the disease. (wikipedia.org)
  • Individuals with Refsum disease present with neurologic damage, cerebellar degeneration, and peripheral neuropathy. (wikipedia.org)
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