Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.
Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.
Infections with bacteria of the genus STAPHYLOCOCCUS.
A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively binds to the Fc region of human normal and myeloma-derived IMMUNOGLOBULIN G. It elicits antibody activity and may cause hypersensitivity reactions due to histamine release; has also been used as cell surface antigen marker and in the clinical assessment of B lymphocyte function.
Techniques used in studying bacteria.
Non-susceptibility of a microbe to the action of METHICILLIN, a semi-synthetic penicillin derivative.
A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Poisoning by staphylococcal toxins present in contaminated food.
INFLAMMATION of the UDDER in cows.
A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.
A phenothiazine that has been used as a hemostatic, a biological stain, and a dye for wool and silk. Tolonium chloride has also been used as a diagnostic aid for oral and gastric neoplasms and in the identification of the parathyroid gland in thyroid surgery.
One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
A family of 3,3-bis(p-hydroxyphenyl)phthalides. They are used as CATHARTICS, indicators, and COLORING AGENTS.
Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.
Viruses whose host is Staphylococcus.
An antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.
A family of bacteria ranging from free living and saprophytic to parasitic and pathogenic forms.
Enzymes which catalyze the hydrolases of ester bonds within DNA. EC 3.1.-.
A technique of bacterial typing which differentiates between bacteria or strains of bacteria by their susceptibility to one or more bacteriophages.
The presence of an infectious agent on instruments, prostheses, or other inanimate articles.
A species of gram-positive bacteria in the family STAPHYLOCOCCACEAE. It is responsible for skin and soft-tissue infections among others, and is part of the normal human skin flora.
A species of STAPHYLOCOCCUS found on the skin of humans (and non-human primates), often causing hospital-acquired infections (CROSS INFECTION).
Any infection which a patient contracts in a health-care institution.
A species of STAPHYLOCOCCUS that is a spherical, non-motile, gram-positive, chemoorganotrophic, facultative anaerobe. Mainly found on the skin and mucous membrane of warm-blooded animals, it can be primary pathogen or secondary invader.
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
INFLAMMATION of the BREAST, or MAMMARY GLAND.
The process of protecting various samples of biological material.
Substances that reduce the growth or reproduction of BACTERIA.
Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.
An enzyme that catalyzes the endonucleolytic cleavage to 3'-phosphomononucleotide and 3'-phospholigonucleotide end-products. It can cause hydrolysis of double- or single-stranded DNA or RNA. (From Enzyme Nomenclature, 1992) EC 3.1.31.1.
Tests that are dependent on the clumping of cells, microorganisms, or particles when mixed with specific antiserum. (From Stedman, 26th ed)
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
The white liquid secreted by the mammary glands. It contains proteins, sugar, lipids, vitamins, and minerals.
The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.
Pneumonia caused by infections with bacteria of the genus STAPHYLOCOCCUS, usually with STAPHYLOCOCCUS AUREUS.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
A 25-kDa peptidase produced by Staphylococcus simulans which cleaves a glycine-glcyine bond unique to an inter-peptide cross-bridge of the STAPHYLOCOCCUS AUREUS cell wall. EC 3.4.24.75.
Any member of the class of enzymes that catalyze the cleavage of the substrate and the addition of water to the resulting molecules, e.g., ESTERASES, glycosidases (GLYCOSIDE HYDROLASES), lipases, NUCLEOTIDASES, peptidases (PEPTIDE HYDROLASES), and phosphatases (PHOSPHORIC MONOESTER HYDROLASES). EC 3.
Proteins from BACTERIA and FUNGI that are soluble enough to be secreted to target ERYTHROCYTES and insert into the membrane to form beta-barrel pores. Biosynthesis may be regulated by HEMOLYSIN FACTORS.
Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.
The presence of bacteria, viruses, and fungi in food and food products. This term is not restricted to pathogenic organisms: the presence of various non-pathogenic bacteria and fungi in cheeses and wines, for example, is included in this concept.
Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.

Epidemiological characterization of methicillin-resistant Staphylococcus aureus isolated in the North West of England by protein A (spa) and coagulase (coa) gene polymorphisms. (1/806)

In a comparative study, isolates of methicillin-resistant Staphylococcus aureus (MRSA) with known pulsed-field gel electrophoresis (PFGE) and bacteriophage type were analysed by polymerase chain reaction (PCR) and restriction fragment length polymorphisms (RFLP) for additional discriminatory subtyping information. PFGE was previously performed using standardized, commercially available kits and pre-programmed software. Isolates were examined for coagulase (coa) and protein A (spa) gene polymorphisms following PCR amplification of the coa hypervariable and spa repeat regions. Coa gene RFLPs produced a total of 38 distinct combined patterns after digestion with HaeIII and AluI and identified the predominant epidemic (EMRSA) types 15 and 16. A unique HaeIII restriction site was identified by RFLP and sequence analysis in the coa gene for EMRSA 15 but not EMRSA 16. The spa gene PCR yielded a total of 14 different profiles ranging from 3-18 repeats with the 2 predominant EMRSA types falling into 2 distinct groups. PCR detection of coa and spa polymorphisms offer a rapid preliminary strain identification and discriminatory subtyping information for surveillance of MRSA.  (+info)

Changing susceptibilities of coagulase-negative staphylococci to teicoplanin in a teaching hospital. (2/806)

The susceptibility of two collections of coagulase-negative staphylococci (CNS) isolated from clinical specimens for teicoplanin and vancomycin were compared. They comprised 91 and 101 isolates, collected in 1985 and 1994 respectively, from different departments of a teaching hospital. MICs of vancomycin and teicoplanin were determined by a modified Etest method. Additionally, a disc diffusion test was performed for teicoplanin. All isolates were susceptible to vancomycin (MIC < or = 4 mg/L). Two of the 91 isolates collected in 1985 were intermediate to teicoplanin (MIC between 8 and 32 mg/L), whereas in 1994 the number of intermediate isolates was 20 out of 101 (P < 0.01). The correlation between MICs, as determined by the modified Etest assay, and disc diffusion zones was poor (r = -0.35). Results show that resistance to teicoplanin in CNS has increased in the study hospital over a period of 9 years. This increase is likely to be correlated with the introduction of teicoplanin. Furthermore, a disc diffusion method does not appear to be the first method of choice for detection of strains of CNS with diminished susceptibility to teicoplanin.  (+info)

Rapid identification of Staphylococcus aureus by using fluorescent staphylocoagulase assays. (3/806)

Two rapid (1-h) assays for the detection of Staphylococcus aureus staphylocoagulase were developed by using the fluorogenic thrombin substrates N-t-boc-Val-Pro-Arg-7-amido-4-methylcoumarin (VPA) and N-t-boc-beta-benzyl-Asp-Pro-Arg-7-amido-4-methylocoumarin (BB). The assays were compared to the tube coagulase test and latex agglutination (LA) (Sanofi Diagnostics Pasteur, Guildford, Surrey, United Kingdom) by using 406 clinical isolates of staphylococci, and they produced positive and negative predictive values of 99.2 and 99. 1% for LA, 98.9 and 92.7% for VPA, and 98.9 and 99.1% for BB. Fluorescent assays used colonies from solid media, thereby eliminating the need for broth cultures, and were performed in microtiter trays, thus making them suitable for large-scale screening.  (+info)

The Staphylococcus aureus rsbW (orf159) gene encodes an anti-sigma factor of SigB. (4/806)

SigB, a newly discovered alternative sigma factor of Staphylococcus aureus, has been shown to play an important role in stress responses and the regulation of virulence factors. The rsbW (orf159) gene is immediately upstream of sigB. Its gene product is homologous to Bacillus subtilis RsbW which under appropriate conditions binds to B. subtilis SigB and functions as an anti-sigma factor or negative posttranslational regulator. To define the function of S. aureus RsbW, both the S. aureus SigB and RsbW proteins were expressed in Escherichia coli and purified. Cross-linking experiments with these purified proteins revealed that RsbW was capable of specific binding to SigB. In an in vitro transcription runoff assay, RsbW prevented SigB-directed transcription from the sar P3 promoter, a known SigB-dependent promoter, and the inhibitory activity of RsbW was found to be concentration dependent. We also identified SigB promoter consensus sequences upstream of the genes encoding alkaline shock protein 23 and coagulase and have demonstrated SigB and RsbW dependence for the promoters in vitro. These results show that RsbW is a protein sequestering anti-sigma factor of S. aureus SigB and suggest that SigB activity in S. aureus is regulated posttranslationally.  (+info)

Use of semi-quantitative and quantitative culture methods and typing for studying the epidemiology of central venous catheter-related infections in neonates on parenteral nutrition. (5/806)

To study the epidemiology - especially the impact of contaminated stopcocks - on central venous catheter (CVC) infection and catheter-related sepsis (CRS), semi-quantitative (SQ) and quantitative (Q) culture methods and typing of coagulase-negative staphylococci (CNS) were employed in 49 neonates with clinical signs of sepsis while receiving parenteral nutrition in the paediatric intensive care unit. The patients were divided into two groups according to stopcock contamination: group A consisted of 18 patients (36%) with contaminated stopcocks and group B consisted of 31 patients (64%) with sterile stopcocks. Five specimens were obtained from each patient, in addition to that from the stopcock: a swab taken from the skin surrounding the catheter puncture site; the CVC tip; the intradermal segment (IDC); and samples of parenteral fluid and blood. A total of 294 specimens (392 sites) was cultured and micro-organisms were identified. All CNS isolated were typed by biotyping, antibiogram, plasmid analysis and pulsed-field gel electrophoresis (PFGE), and the discriminatory power of the typing methods was compared. The CVC tips were infected in 25 patients (51%); 15 (83%) in group A and 10 (32%) in group B. Sepsis was detected in 24 neonates (49%), 13 in group A and 11 in group B. This was catheter-related in 15 patients (63%), 12 in group A and 3 in group B. CNS were recovered from 13 (52%) of 25 infected CVCs, nine in group A and four in group B. Sixty-five CNS isolates were recovered from these patients and belonged to 14 biotypes, 22 antibiograms, 22 plasmid profiles and 26 PFGE types. Typing showed that in six of nine patients in group A, CNS of the same type were recovered from the catheter tip and the stopcock, in one patient the catheter tip and skin isolates were the same and in two others the catheter tip isolates were different from stopcock and skin isolates. In all four patients in group B, different CNS types were recovered from CVC tips and skin. Bacteraemia was caused by CNS in 14 patients (58%), six in group A and eight in group B. Typing confirmed that nine cases (six in group A and three in group B) were catheter-related but five were not. SQ and Q culture methods and typing, especially by PFGE, allowed the study to determine that bacteria from contaminated stopcocks were frequently the source of CVC infection and CRS.  (+info)

Oxacillin susceptibility testing of staphylococci directly from Bactec Plus blood cultures by the BBL Crystal MRSA ID system. (6/806)

The BBL Crystal MRSA ID test (Becton Dickinson) was applied directly to blood culture vials containing clusters of gram-positive cocci. The sensitivity and specificity of the test were 84 and 100% and 54 and 100% for vials containing Staphylococcus aureus and coagulase-negative staphylococci, respectively. This test is a reliable method for direct detection of methicillin resistance in positive blood culture vials when S. aureus is identified in parallel by rapid identification procedures.  (+info)

Analysis of genomic diversity within the Xr-region of the protein A gene in clinical isolates of Staphylococcus aureus. (7/806)

Protein A of Staphylococcus aureus contains a polymorphic Xr-region characterized by a tandem repeat of eight amino acid units. In this study, the diversity of genes encoding the repeat regions and their relatedness among S. aureus strains was analyzed. Ten different protein-A types characterized by repeat numbers 4-13 were identified in a total of 293 clinical isolates. The protein-A type with 10 repeat units (10 repeats) in the Xr-region was most frequently detected in methicillin-resistant S. aureus, whereas the majority of methicillin-susceptible strains were distributed almost evenly into protein-A types with 7-11 repeats. Strains that belonged to a single coagulase type were classified into multiple protein-A types, e.g. strains with the common coagulase types II and VII were differentiated into 7 and 8 protein-A types, respectively. Nucleotide sequence analysis of the Xr-region of 42 representative strains revealed the presence of 37 different genotypes (spa types), which were constituted by a combination of several of 24 different repeat unit genotypes. Based on the similarity in arrangement of repeat unit genotypes, 34 strains with different repeat numbers were classified into 5 genetic clusters (C1-C5). The clusters C1, C2 and C3 consisted exclusively of strains with identical coagulase types II, III, and IV, respectively. These findings suggested that the protein-A gene of S. aureus has evolved from a common ancestral clone in individual clusters independently.  (+info)

Coagulase gene polymorphism of Staphylococcus aureus isolates from dairy cattle in different geographical areas. (8/806)

The objectives of this study were to investigate the coagulase gene polymorphism of Staphylococcus aureus isolates obtained from bovine mastitic milk and to determine the resistance of predominant and rare coagulase genotypes to bovine blood neutrophil bactericidal activities. A total of 453 isolates were collected from four countries: the Czech Republic, France, Korea and the United States. The isolates were subtyped into 40 types by restriction fragment length polymorphism (RFLP) of the coagulase gene. Twenty-three strains from predominant and rare genotypes were evaluated for their ability to resist neutrophil bactericidal activities. There were significant (P < 0.01) differences in the average percent neutrophil killing of the predominant (16.7%) and rare (39.7%) genotypes when bacteria were opsonized with antiserum. The results indicate that the profiles of coagulase genotype differ among geographic locations, and only a few genotypes prevail in each location. In addition, the predominant genotypes were more resistant to neutrophil bactericidal activities than rare genotypes.  (+info)

Staphylococcal infections can be classified into two categories:

1. Methicillin-Resistant Staphylococcus Aureus (MRSA) - This type of infection is resistant to many antibiotics and can cause severe skin infections, pneumonia, bloodstream infections and surgical site infections.

2. Methicillin-Sensitive Staphylococcus Aureus (MSSA) - This type of infection is not resistant to antibiotics and can cause milder skin infections, respiratory tract infections, sinusitis and food poisoning.

Staphylococcal infections are caused by the Staphylococcus bacteria which can enter the body through various means such as:

1. Skin cuts or open wounds
2. Respiratory tract infections
3. Contaminated food and water
4. Healthcare-associated infections
5. Surgical site infections

Symptoms of Staphylococcal infections may vary depending on the type of infection and severity, but they can include:

1. Skin redness and swelling
2. Increased pain or tenderness
3. Warmth or redness in the affected area
4. Pus or discharge
5. Fever and chills
6. Swollen lymph nodes
7. Shortness of breath

Diagnosis of Staphylococcal infections is based on physical examination, medical history, laboratory tests such as blood cultures, and imaging studies such as X-rays or CT scans.

Treatment of Staphylococcal infections depends on the type of infection and severity, but may include:

1. Antibiotics to fight the infection
2. Drainage of abscesses or pus collection
3. Wound care and debridement
4. Supportive care such as intravenous fluids, oxygen therapy, and pain management
5. Surgical intervention in severe cases.

Preventive measures for Staphylococcal infections include:

1. Good hand hygiene practices
2. Proper cleaning and disinfection of surfaces and equipment
3. Avoiding close contact with people who have Staphylococcal infections
4. Covering wounds and open sores
5. Proper sterilization and disinfection of medical equipment.

It is important to note that MRSA (methicillin-resistant Staphylococcus aureus) is a type of Staphylococcal infection that is resistant to many antibiotics, and can be difficult to treat. Therefore, early diagnosis and aggressive treatment are crucial to prevent complications and improve outcomes.

Staphylococcal food poisoning is typically caused by consuming food that has been contaminated with the bacterium, often through improper handling or storage of food products. Symptoms usually begin within 1-7 days after consumption of contaminated food, and can last for several days to a week or more.

Treatment for staphylococcal food poisoning typically involves supportive care, such as hydration and rest, as well as antibiotics in severe cases. In severe cases, hospitalization may be necessary to manage complications such as kidney failure or sepsis. Prevention measures include proper handling and storage of food products, cooking food to the appropriate temperature, and avoiding cross-contamination of foods.

The most common symptoms of bovine mastitis include:

1. Swelling and redness of the udder
2. Increased temperature of the affected quarter
3. Pain or discomfort in the udder
4. Decreased milk production
5. Abnormal milk appearance (e.g., clots, pus, or blood)

If left untreated, mastitis can lead to more severe complications such as abscesses, septicemia, or even death of the animal. Therefore, early detection and proper treatment are crucial to prevent the spread of infection and reduce the severity of clinical signs.

Diagnosis of bovine mastitis is typically based on a combination of clinical examination, milk culture, and laboratory tests (e.g., blood counts, serum biochemistry). Treatment involves antibiotics, supportive care (e.g., fluids, pain management), and identification of the underlying cause to prevent future occurrences.

Prevention of bovine mastitis is key to maintaining a healthy and productive dairy herd. This includes proper sanitation and hygiene practices, regular milking techniques, and effective dry cow therapy. Vaccination against common mastitis-causing pathogens may also be considered in some cases.

Overall, bovine mastitis is a significant health issue in dairy cattle that can have significant economic and welfare implications for farmers and the industry as a whole. Proper diagnosis, treatment, and prevention strategies are essential to maintain a healthy and productive herd.

In medicine, cross-infection refers to the transmission of an infectious agent from one individual or source to another, often through direct contact or indirect exposure. This type of transmission can occur in various settings, such as hospitals, clinics, and long-term care facilities, where patients with compromised immune systems are more susceptible to infection.

Cross-infection can occur through a variety of means, including:

1. Person-to-person contact: Direct contact with an infected individual, such as touching, hugging, or shaking hands.
2. Contaminated surfaces and objects: Touching contaminated surfaces or objects that have been touched by an infected individual, such as doorknobs, furniture, or medical equipment.
3. Airborne transmission: Inhaling droplets or aerosolized particles that contain the infectious agent, such as during coughing or sneezing.
4. Contaminated food and water: Consuming food or drinks that have been handled by an infected individual or contaminated with the infectious agent.
5. Insect vectors: Mosquitoes, ticks, or other insects can transmit infections through their bites.

Cross-infection is a significant concern in healthcare settings, as it can lead to outbreaks of nosocomial infections (infections acquired in hospitals) and can spread rapidly among patients, healthcare workers, and visitors. To prevent cross-infection, healthcare providers use strict infection control measures, such as wearing personal protective equipment (PPE), thoroughly cleaning and disinfecting surfaces, and implementing isolation precautions for infected individuals.

In summary, cross-infection refers to the transmission of an infectious agent from one individual or source to another, often through direct contact or indirect exposure in healthcare settings. Preventing cross-infection is essential to maintaining a safe and healthy environment for patients, healthcare workers, and visitors.

Bacteremia can occur when bacteria enter the bloodstream through various means, such as:

* Infected wounds or surgical sites
* Injecting drug use
* Skin infections
* Respiratory tract infections
* Urinary tract infections
* Endocarditis (infection of the heart valves)

The symptoms of bacteremia can vary depending on the type of bacteria and the severity of the infection. Some common symptoms include:

* Fever
* Chills
* Headache
* Muscle aches
* Weakness
* Confusion
* Shortness of breath

Bacteremia is diagnosed by blood cultures, which involve collecting blood samples and inserting them into a specialized container to grow the bacteria. Treatment typically involves antibiotics and supportive care, such as intravenous fluids and oxygen therapy. In severe cases, hospitalization may be necessary to monitor and treat the infection.

Prevention measures for bacteremia include:

* Practicing good hygiene, such as washing hands regularly
* Avoiding sharing personal items like toothbrushes or razors
* Properly cleaning and covering wounds
* Getting vaccinated against infections that can lead to bacteremia
* Following proper sterilization techniques during medical procedures

Overall, bacteremia is a serious condition that requires prompt medical attention to prevent complications and ensure effective treatment.

Symptoms of mastitis may include:

* Pain and tenderness in the breast
* Redness and swelling of the skin
* Fever and chills
* Difficulty breathing (in severe cases)

Treatment for mastitis usually involves antibiotics to clear up any bacterial infections, as well as measures to relieve pain and discomfort such as warm compresses, massage, and over-the-counter pain medication. In some cases, hospitalization may be necessary if the infection is severe or if the person has a fever that is difficult to control.

Preventative measures for mastitis include:

* Properly storing and handling breast milk
* Frequently checking and emptying the breasts to prevent clogged milk ducts
* Avoiding tight clothing or bras that can constrict the breasts
* Practicing good hygiene, such as washing hands before handling the breasts

It is important for individuals with mastitis to seek medical attention if they experience any of the following symptoms:

* High fever (over 101°F)
* Difficulty breathing
* Severe pain that does not improve with medication
* Redness or swelling that spreads beyond the breast area.

Staphylococcal pneumonia is an infection of the lungs that occurs when the bacteria enter the lungs and cause inflammation. This condition can be particularly dangerous for certain groups of people, such as children under the age of two, adults over the age of 65, and those with weakened immune systems or chronic medical conditions.

The symptoms of staphylococcal pneumonia can vary depending on the severity of the infection, but they may include:

* Fever and chills
* Cough, which may be dry or produce mucus
* Chest pain that worsens with deep breathing or coughing
* Shortness of breath
* Headache
* Muscle aches and fatigue
* Confusion or disorientation in older adults

Staphylococcal pneumonia is typically diagnosed through a combination of physical examination, medical history, and diagnostic tests such as chest X-rays or blood tests. Treatment typically involves antibiotics, which can help clear the infection and reduce symptoms. In severe cases, hospitalization may be necessary to provide supportive care, such as oxygen therapy or mechanical ventilation.

Prevention of staphylococcal pneumonia is key, and this includes:

* Vaccination: The pneumococcal conjugate vaccine (PCV) is recommended for children under the age of two and adults over the age of 65, as well as those with certain medical conditions.
* Good hygiene practices: Washing hands regularly, covering the mouth and nose when coughing or sneezing, and avoiding close contact with people who are sick can help prevent the spread of the bacteria.
* Avoiding risky behaviors: Avoiding sharing personal items, such as toothbrushes or drinking glasses, and not engaging in risky behaviors like unprotected sex or sharing needles can also help prevent the spread of the bacteria.

It is important to seek medical attention if you or a loved one is experiencing symptoms of pneumonia, as early treatment can help prevent complications and improve outcomes.

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S. epidermidis, a coagulase-negative staphylococcus species, is a commensal of the skin, but can cause severe infections in ... S. saprophyticus, another coagulase-negative species that is part of the normal vaginal flora, is predominantly implicated in ... The main coagulase-positive staphylococcus is Staphylococcus aureus, although not all strains of Staphylococcus aureus are ... Becker K, Heilmann C, Peters G (October 2014). "Coagulase-negative staphylococci". Clin. Microbiol. Rev. 27 (4): 870-926. doi: ...
S. aureus is coagulase-positive, meaning it produces coagulase. However, while the majority of S. aureus strains are coagulase- ... S. epidermidis, a coagulase-negative species, is a commensal of the skin, but can cause severe infections in immunosuppressed ... S. saprophyticus, another coagulase-negative species that is part of the normal vaginal flora, is predominantly implicated in ... A new coagulase negative species - Staphylococcus edaphicus - has been isolated from Antarctica. This species is probably a ...
Becker K, Heilmann C, Peters G (October 2014). "Coagulase-negative staphylococci". Clinical Microbiology Reviews. 27 (4): 870- ...
schleiferi (coagulase negative) and Staphylococcus schleiferi subsp. coagulans (coagulase positive). Staphylococcus schleiferi ... but because there is a coagulase positive and a coagulase negative subspecies of S. schleiferi, additional biochemical tests ... Later in 1990, a coagulase-positive subtype was isolated from dogs and cats by Igimi et al. This led to the classification of ... It is facultatively anaerobic, coagulase-variable, and can be readily cultured on blood agar where the bacterium tends to form ...
Tefibazumab Coagulase Hair PS; Ward MD; Semmes OJ; Foster TJ; Cunnion KM (July 2008). "Staphylococcus aureus clumping factor A ...
S. caprae is coagulase-negative. It was originally isolated from goats (caprae means "of a goat"), but members of this species ... It is a coagulase-negative, DNase-positive member of the genus Staphylococcus. Usually it is associated with goats. Since 1991 ... "Identification of coagulase-negative staphylococci other than Staphylococcus epidermidis by automated ribotyping". Clin ...
The coagulase test determines whether an organism can produce the enzyme coagulase, which causes the fibrin to clot. ... A clot indicates the presence of coagulase, while no clot indicates the lack of coagulase. DNase agar is used to test whether a ... "Welcome to Microbugz - Coagulase Test". www.austincc.edu. Retrieved 2017-04-03. "Welcome to Microbugz - DNase Test". www. ... Inoculating a plasma test tube with the microbe indicates whether coagulase is produced. ...
nov., a coagulase-variable species from bovine subclinical and mild clinical mastitis". International Journal of Systematic and ... Staphylococcus agnetis is a Gram positive, coagulase-variable member of the bacterial genus Staphylococcus. Strains of this ... "Coagulase-positive staphylococci: my pet's two faces". Research in Microbiology. 164 (5): 371-374. doi:10.1016/j.resmic.2013.02 ...
Coagulase, lipase, and DNAase produced by the bacteria also aid in its dissemination throughout the host body. Staphyloccus ... nov., a coagulase-positive species from animals". International Journal of Systematic and Evolutionary Microbiology. 55 (Pt 4 ... Due to its ability to clot blood, S. pseudintermedius subcategorized into a group of coagulase positive (CoPS) staphylococci.[ ... This can be useful for differentiating S. pseudintermedius from coagulase negative Staphylococci, and from S. aureus which ...
It is a catalase-positive, coagulase-negative, facultative anaerobe that can grow by aerobic respiration or by fermentation. ... ISBN 978-1-55581-171-6. Queck SY, Otto M (2008). "Staphylococcus epidermidis and other Coagulase-Negative Staphylococci". ... which is coagulase-negative, as well, but novobiocin-resistant. Similar to those of S. aureus, the cell walls of S. epidermidis ... catalase and slide coagulase testing. Zobell agar is useful for the isolation of Staphylococcus epidermidis from marine ...
... some strains isolated from both pigs and cattle have been found to be coagulase negative so it can be considered coagulase ... Martins PD, de Almeida TT, Basso AP, de Moura TM, Frazzon J, Tondo EC, Frazzon AP (September 2013). "Coagulase-positive ... March 2010). "Multiplex-PCR method for species identification of coagulase-positive staphylococci". Journal of Clinical ... Most strains of S. hyicus are coagulase positive; however, ... coagulase production to form clots, surface fibronectin-binding ...
"Meticillin resistance in orthopaedic coagulase-negative staphylococcal infections". The Journal of Hospital Infection. 79 (3): ...
Many of the isolated strains show coagulase activity. Clinical tests for detection of methicillin-resistant S. aureus may ... "Biochemical markers and protein pattern analysis for canine coagulase-positive staphylococci and their distribution on dog skin ... "Multiplex-PCR Method for Species Identification of Coagulase-Positive Staphylococci". Journal of Clinical Microbiology. 48 (3 ...
nov., a Coagulase-Positive Species Isolated from Dolphins". International Journal of Systematic Bacteriology. 38 (4): 436-439. ... nov., a coagulase-positive species isolated from dolphins. International Journal of Systematic Bacteriology, 38(4), 436-439. ... Staphylococcus delphini is a Gram-positive, coagulase-positive member of the bacterial genus Staphylococcus consisting of ... "coagulase, phosphatase, heat-labile deoxyribonuclease production, carbohydrate reaction pattern, bacteriolytic activity pattern ...
The opposite of coagulase, kinases can dissolve clots. S. aureus can also produce staphylokinase, allowing them to dissolve the ... By binding to prothrombin, coagulase facilitates clotting in a cell by ultimately converting fibrinogen to fibrin. Bacteria ...
In this context, a distinction is made in species between coagulase-positive and coagulase-negative staphylococci. ... Staphylococcus capitis is a coagulase-negative species (CoNS) of Staphylococcus. It is part of the normal flora of the skin of ... Other therapeutically relevant coagulase negative staphylococci have closer evolutionary ties to S. epidermidis than S. capitis ... Coagulase Negative Staphylococcus CNS Type strain of Staphylococcus capitis at BacDive - the Bacterial Diversity Metadatabase ( ...
Common bacteria are coagulase-negative Staphylococcus and Cutibacterium acnes. Late - more than 24 months. It is usually ... coagulase-negative staphylococci - usually due to prosthetic joint Streptococci - the second-most common cause (28%) ... Prosthetic joint infection - Artificial joint infection are usually caused by coagulase negative Staphylococci, Staphylococcus ...
nov.: Three New Coagulase-Negative, Novobiocin-Resistant Species from Animals". Systematic and Applied Microbiology. 5 (4): 501 ... Staphylococcus arlettae is a gram-positive, coagulase-negative member of the bacterial genus Staphylococcus consisting of ...
nov.: Three New Coagulase-Negative, Novobiocin-Resistant Species from Animals". Systematic and Applied Microbiology. 5 (4): 501 ... Staphylococcus equorum is a gram-positive, coagulase-negative member of the bacterial genus Staphylococcus consisting of ...
Strains of this species were originally isolated from otters and are coagulase-positive. Foster, G.; Ross, H. M.; Hutson, R. A ... nov., a New Coagulase-Positive Species Isolated from Otters". International Journal of Systematic Bacteriology. 47 (3): 724-726 ...
nov.: Three New Coagulase-Negative, Novobiocin-Resistant Species from Animals". Systematic and Applied Microbiology. 5 (4): 501 ... Staphylococcus kloosii in a gram-positive, coagulase-negative member of the bacterial genus Staphylococcus consisting of single ...
S. aureus produces various enzymes such as coagulase (bound and free coagulases) which facilitates the conversion of fibrinogen ... Previously, S. aureus was differentiated from other staphylococci by the coagulase test. However, not all S. aureus strains are ... Hanselman BA, Kruth SA, Rousseau J, Weese JS (September 2009). "Coagulase positive staphylococcal colonization of humans and ... Furthermore, for differentiation on the species level, catalase (positive for all Staphylococcus species), coagulase (fibrin ...
Additionally, they are facultative anaerobic, coagulase negative and catalase positive. The type strain (51-48T = CCUG 73747T ... "Antimicrobial susceptibility and body site distribution of community isolates of coagulase-negative staphylococci". APMIS. 124 ...
However, Staphylococcus aureus, coagulase-negative staphylococci and enterococci are resistant. It is also used to treat ...
Numerous coagulase-negative staphylococci appear commonly on the skin of human. Of these species, S. epidermidis and S. hominis ... Like many other coagulase-negative staphylococci, S. hominis may occasionally cause infection in patients whose immune systems ... This supports the idea that health workers serve as a form of nosocomial transmission of coagulase-negative staphylococi. If ... More undocumented instances of SHN infections may not have been reported because not all coagulase-negative staphylococcal ...
It is now widely recommended by national and international bodies for the isolation of coagulase-positive staphylococci. Braid- ... Baird-Parker, A. C. (1962). "AN IMPROVED DIAGNOSTIC AND SELECTIVE MEDIUM FOR ISOLATING COAGULASE POSITIVE STAPHYLOCOCCI". ... Parker agar is commonly use as a method for the enumeration of coagulase-positive staphylococci (Staphylococcus aureus and ... A SELECTIVE PLATING MEDIUM FOR THE QUANTITATIVE DETECTION OF COAGULASE-POSITIVE STAPHYLOCOCCI". Journal of Bacteriology. 70 (6 ...
Vancomycin plus ceftazidime cover infections caused by common organisms (e.g. Bacillus species, coagulase-negative ...
Like other coagulase-negative staphylococci, S. warneri rarely causes disease, but may occasionally cause infection in patients ... 1986) Identification of coagulase-negative Staphylococci isolated from urinary tract infections. Am. J. Clin. Pathol. 85(1):92- ... It is catalase-positive, oxidase-negative, and coagulase-negative, and is a common commensal organism found as part of the skin ... Similar to other coagulase-negative staphylococci, the presence of S. warneri in blood and cerebrospinal fluid cultures can ...
... is a member of the coagulase-negative staphylococci (CoNS). It is part of the skin flora of humans ... 2001). "Rapid and Accurate Species-Level Identification of Coagulase-Negative Staphylococci by Using the sodA Gene as a Target ... 2002). "The ica Operon and Biofilm Production in Coagulase-Negative Staphylococci Associated with Carriage and Disease in a ... 2007). "Persistent strains of coagulase-negative staphylococci in a neonatal intensive care unit: virulence factors and ...
Are coagulase-negative Staphylococcus (CoNS) species important? Although the clinical significance of CoNS isolated in culture ... Laboratory Detection of Coagulase-negative Staphylococcus species with Decreased Susceptibility to the Glycopeptides Vancomycin ... Emergence of vancomycin resistance in coagulase-negative staphylococci. New England Journal of Medicine 316:927-931. ...
... both coagulase-positive and coagulase-negative Staphylococcus species (CoNS), have major medical significance.1 Coagulase- ... Coagulase Mannitol Agar. Intended Use. Coagulase Mannitol Agar is used for the differentiation of Staphylococcus aureus from ... Coagulase Mannitol Agar aids in the differentiation of staphylococci by indicating the presence of coagulase and the ... Some old or mutant strains of S. aureus may be weak coagulase producers or exhibit negative coagulase reactions and should be ...
Biofilm production was studied in 80 coagulase-negative staphylococci (CNS) strains isolated from clinical specimens of ... The ability of biofilm formation seems to play an essential role in the virulence of coagulase-negative staphylococci (CNS). ... Table 2 Sensitivity and specificity of phenotypic methods for the detection of biofilm production in coagulase-negative ... Table 1 Frequency of coagulase-negative staphylococci isolated from different clinical specimens. Full size table. ...
Staphylococcus (coagulase-negative + methicillin-susceptible). -. 0.28. ? - ?. Dalbavancin. 1112. Staphylococcus (coagulase- ... Staphylococcus (CN11 + coagulase-negative + methicillin-resistant). *Staphylococcus (CN3 + coagulase-negative + methicillin- ... Staphylococcus (CN3 + coagulase-negative + methicillin-susceptible). *Staphylococcus (CN5 + coagulase-negative + methicillin- ... Home › Search by Microorganism › Staphylococcus (coagulase-negative + methicillin-susceptible) *Staphylococcus (coagulase- ...
Coagulase-Negative Staphylococci Contained in Gut Microbiota as a Primary Source of Sepsis in Low- and Very Low Birth Weight ... There are only a few reports in the literature about translocation of coagulase-negative staphylococci (CoNS) as a primary ...
This study aimed to characterise linezolid-resistant coagulase-negative staphylococci (CoNS) isolates and the possibility of ... Phenotypic and genotypic characterisation of linezolid-resistant coagulase-negative staphylococci possessing cfr-carrying ... Phenotypic and genotypic characterisation of linezolid-resistant coagulase-negative staphylococci possessing cfr-carrying ...
Horizontal method for the enumeration of coagulase-positive staphylococci (Staphylococcus aureus and other species) - Part 3: ... Microbiology of the food chain - Horizontal method for the enumeration of coagulase-positive staphylococci (Staphylococcus ...
Coagulase-negative staphylococci. Aerobic gram-negative bacilli, including Pseudomonas aeruginosa. Basilar skull fracture ...
Direct tube coagulase and direct cefoxitin disk diffusion test. The tube coagulase test was performed directly from the blood ... Specimens that were negative by direct-tube coagulase were subjected to slide and/or tube coagulase testing from isolated ... Direct tube coagulase and DCDD test. As shown in Table 3, using standardized phenotypic methods and MecA-PCR, all S. aureus ... Lorsque les staphylocoques à coagulase négative ont été analysés, la sensibilité pour la détection de la résistance à la ...
We selected 30 patients who had staphylococcus aureus and coagulase-negative sepsis and used vancomycin as a treatment. We ... Newborns with staphylococcus aureus and coagulase-negative sepsis treated with vancomycin after an increase in serum levels ... of vancomycin in newborns with Staphylococcus aureus infection or oxacillin-resistant coagulase-negative. METHODS: This is an ...
Coagulase- negative Staphylococci except S. lugdenensis. Oxacillind. -. -. -. -. ≤ 0.25. -. ≥ 0.5. 30 mcg. cefoxitinb. ≥ 25. - ... 2d Oxacillin MIC interpretive criteria may overcall resistance for some coagulase-negative staphylococci (CoNS), because some ...
A tube coagulase test using rabbit plasma with EDTA was then performed on Staphaurex-negative isolates from BAP with morphology ... Staphaurex-positive tube coagulase-negative isolates were discarded. S. aureus isolates were screened for methicillin ... Staphaurex-positive isolates and Staphaurex-negative tube coagulase-positive isolates were identified as S. aureus and saved ...
Fertilizers, soil conditioners and beneficial substances - Microbiology- Detection of Staphylococcus aureus coagulase-positive ...
6.6.2. Coagulase-Negative Staphylococci infections. 6.7. Streptococcal/Enterococcal Infections, Diptheria, Corynebacteria ...
... both coagulase-negative Staphylococcus and gram-negative rods grew in 1 culture. Both were considered pathogens of probable ... This suggests that tigecycline may have also been useful for the coagulase-negative staphylococci identified in this patient ...
The biofilm of coagulase-negative S aureus (CoNS) protects the pathogen from the hosts defenses, as well as from various ... The 3- to 24-month group usually are caused by coagulase-negative S aureus (CoNS) or gram-negative aerobes, both of which are ... The most common pathogens were coagulase-negative Staphylococcus (CoNS), MSSA, and enterococci. [5] ...
Blood culture, in that period, identified a catheter-related growth of coagulase-negative Staphylococcus. One week later, a new ... Central culture was positive for coagulase-negative staphylococci. The child was in complete remission one month after the ...
The remaining six isolates were coagulase-negative staphylococci. The culture-molecular approach adopted here had an overall ...
Coagulase (-) Staphylococcus aureus *Contraindicated in renal impairment and folate deficiency Multiple drug interactions. Not ... Lactobacillus spp; Coagulase (-) Staphylococci and Corynebacterium spp are not considered clinically relevant bacteria ...
The assay can distinguish coagulase-negative Staphylococci from pathogenic Staphylococci, the company said. ... The assay can distinguish coagulase-negative Staphylococci from pathogenic Staphylococci, the company said. The panel received ...
Dry conditions favor the persistence of gram-positive cocci (e.g., coagulase-negative Staphylococcus spp.) in dust and on ...
Staphylococcus epidermidis and other coagulase-negative staphylococci. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, ...
Blood banks in Holland reported coagulase-negative staphylococci to be the most common bacteria isolated [12] ...
For coagulase-negative staphylococci (n = 7), viridans group streptococci (n = 15), and beta-hemolytic streptococci (n = 3), ...
Coagulase Positive Staphylococci (Enumeration) £155.00 Coagulase Positive Staphylococci Enumeration in Beef Proficiency Test ... Coagulase Positive Staphylococci Enumeration in Beef Proficiency Test FMOE14-MRP2 M287e14 19/06/2023 Proficiency Test Beef ... Coagulase Positive Staphylococci (Enumeration) £155.00 Aerobic Plate Count, Enterobacteriaceae, Coliforms and Escherichia coli ...
  • Are coagulase-negative Staphylococcus (CoNS) species important? (cdc.gov)
  • Coagulase Mannitol Agar is used for the differentiation of Staphylococcus aureus from other species based on coagulase production and mannitol utilization. (p212121.com)
  • Staphylococci, both coagulase-positive and coagulase-negative Staphylococcus species (CoNS), have major medical significance. (p212121.com)
  • In contrast, a coagulase-negative species that does not utilize mannitol, such as Staphylococcus epidermidis, does not change the color of the medium and it remains clear. (p212121.com)
  • Sur 60 hémocultures positives pour les cocci à Gram positif en grappes, l'amplification isotherme induite par boucle (au moyen du dépistage des gènes FemA et MecA) a montré une sensibilité et une spécificité de 100 % pour l'identification de Staphylococcus aureus résistant et sensible à la méthicilline. (who.int)
  • To analyse the concentration of serum level in the voucher (one hour before the next administration of the drug dose) of vancomycin in newborns with Staphylococcus aureus infection or oxacillin-resistant coagulase-negative. (bvsalud.org)
  • We selected 30 patients who had staphylococcus aureus and coagulase-negative sepsis and used vancomycin as a treatment. (bvsalud.org)
  • both coagulase-negative Staphylococcus and gram-negative rods grew in 1 culture. (cdc.gov)
  • The most common pathogens were coagulase-negative Staphylococcus (CoNS), MSSA, and enterococci. (medscape.com)
  • Staphylococcus epidermidis and other coagulase-negative staphylococci. (medlineplus.gov)
  • 1. Staphylococcus lugdunensis: a rare but destructive cause of coagulase-negative staphylococcus infective endocarditis. (nih.gov)
  • 6. Unusually virulent coagulase-negative Staphylococcus lugdunensis is frequently associated with infective endocarditis: a Waikato series of patients. (nih.gov)
  • 11. Coagulase-negative Staphylococcus endocarditis: Staphylococcus lugdunensis. (nih.gov)
  • 17. The pitfall of coagulase-negative staphylococci: a case of Staphylococcus lugdunensis endocarditis. (nih.gov)
  • The Pathogen Molecular Genetics section investigates physiology and host interaction of Gram-positive pathogens with a focus on Staphylococcus aureus and coagulase-negative staphylococci. (nih.gov)
  • K. pneumoniae, P. mirabilis, coagulase-neg Staphylococcus spp. (medscape.com)
  • Staphylococcus aureus (3 patients) and staphylococcus coagulase negative (3 patients) were the most common infectious agents during direct connection period. (isciii.es)
  • 1987. Emergence of vancomycin resistance in coagulase-negative staphylococci. (cdc.gov)
  • 1 Coagulase-producing staphylococci (S. aureus) may be differentiated and presumptively identified with this medium based on production of coagulase and mannitol utilization. (p212121.com)
  • Coagulase Mannitol Agar aids in the differentiation of staphylococci by indicating the presence of coagulase and the utilization of mannitol. (p212121.com)
  • The ability of biofilm formation seems to play an essential role in the virulence of coagulase-negative staphylococci (CNS). (biomedcentral.com)
  • Biofilm production was studied in 80 coagulase-negative staphylococci (CNS) strains isolated from clinical specimens of newborns with infection hospitalized at the Neonatal Unit of the University Hospital, Faculty of Medicine of Botucatu, and in 20 isolates obtained from the nares of healthy individuals without signs of infection. (biomedcentral.com)
  • Coagulase-negative staphylococci (CNS) are the microorganisms most frequently involved in nosocomial infections among neonates. (biomedcentral.com)
  • Coagulase-Negative Staphylococci Contained in Gut Microbiota as a Primary Source of Sepsis in Low- and Very Low Birth Weight Neonates. (bvsalud.org)
  • There are only a few reports in the literature about translocation of coagulase -negative staphylococci (CoNS) as a primary cause of sepsis in neonates , although CoNS are among a short list of "translocating" bacteria when present in abundance. (bvsalud.org)
  • Phenotypic and genotypic characterisation of linezolid-resistant coagulase-negative staphylococci possessing cfr-carrying plasmid. (illumina.com)
  • This suggests that tigecycline may have also been useful for the coagulase-negative staphylococci identified in this patient and could have been considered as the sole treatment agent. (cdc.gov)
  • The remaining six isolates were coagulase-negative staphylococci. (bl.uk)
  • The assay can distinguish coagulase-negative Staphylococci from pathogenic Staphylococci , the company said. (genomeweb.com)
  • 8. [Infective endocarditis caused by coagulase-negative staphylococci: a review of 19 cases]. (nih.gov)
  • Contamination rates varied from 10% to 100%, with coagulase-negative staphylococci being the most commonly found microorganism, being present on 441 of the tourniquets analyzed. (medindia.net)
  • Coagulase-negative staphylococci can cause a range of infections, including skin and soft tissue infections. (medindia.net)
  • Gordon is interested in the molecular mechanisms underlying the pathogenic success of S. aureus and coagulase-negative staphylococci. (nih.gov)
  • Higher prevalence of coagulase-negative staphylococci carriage among reclaimed water spray irrigators. (cdc.gov)
  • Cardiovascular infections are primarily caused by coagulase positive and negative staphylococci and by other antimicrobial-drug resistant pathogens. (nih.gov)
  • Two coagulase-negative staphylococci emerging as potential zoonotic pathogens: wolves in sheep's clothing? (nih.gov)
  • Listeria and coagulase-positive Staphylococci have been found during inspections of fruit salads in Switzerland, according to the Swiss Association of Cantonal Chemists (ACCS). (foodsafetynews.com)
  • DCDD along with direct tube coagulase assay detected only 80.6% of MRSA/MSSA. (who.int)
  • A tube coagulase test using rabbit plasma with EDTA was then performed on Staphaurex-negative isolates from BAP with morphology consistent with S. aureus and Staphaurex-positive isolates with morphology inconsistent with S. aureus (non-hemolytic). (cdc.gov)
  • Staphaurex-positive isolates and Staphaurex-negative tube coagulase-positive isolates were identified as S. aureus and saved for further testing. (cdc.gov)
  • Staphaurex-positive tube coagulase-negative isolates were discarded. (cdc.gov)
  • Some old or mutant strains of S. aureus may be weak coagulase producers or exhibit negative coagulase reactions and should be subcultured and retested if in doubt. (p212121.com)
  • The identified germ spectrum revealed S. aureus in 29.5% , E. coli in 20.9% , Coagulase neg. (smw.ch)
  • NOTE: The use of BBL Coagulase Plasma, Rabbit with EDTA, in place of citrated plasma, prevents false-positive coagulase reactions by citrate-utilizing microorganisms. (p212121.com)
  • and Marwin introduced tellurite-glycine media designed to selectively isolate coagulase-positive staphylococcal species. (p212121.com)
  • 4. Cool to 50°C and add 7-15% pretested, undiluted rabbit coagulase plasma with EDTA. (p212121.com)
  • S. schleiferi (coagulase positive or negative) was viewed as an uncommon pathogen of dogs and humans. (vin.com)
  • Coagulase production is dependant on the presence of mannitol, a protein factor in the brain heart infusion and blood serum (plasma). (p212121.com)
  • An opaque area of coagulated plasma forms around the colonies of organisms that also produce coagulase. (p212121.com)
  • En parallèle, une identification microbiologique normalisée et un test de sensibilité à l'oxacilline par PCR visant l'amplification du gène MecA ont été réalisés. (who.int)