A species of gram-positive bacteria in the family Clostridiaceae. Its GLUTAMATE DEHYDROGENASE is commonly used in research.
A genus of motile or nonmotile gram-positive bacteria of the family Clostridiaceae. Many species have been identified with some being pathogenic. They occur in water, soil, and in the intestinal tract of humans and lower animals.
An enzyme that catalyzes the conversion of L-glutamate and water to 2-oxoglutarate and NH3 in the presence of NAD+. (From Enzyme Nomenclature, 1992) EC 1.4.1.2.
An enzyme that catalyzes the reaction of ATP, pyruvate, and orthophosphate to form AMP plus phosphoenolpyruvate plus pyrophosphate. EC 2.7.9.1.
A kingdom in the domain ARCHAEA comprised of thermoacidophilic, sulfur-dependent organisms. The two orders are SULFOLOBALES and THERMOPROTEALES.
A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.
Infections with bacteria of the genus CLOSTRIDIUM.
A species of anaerobic, gram-positive, rod-shaped bacteria in the family Clostridiaceae that produces proteins with characteristic neurotoxicity. It is the etiologic agent of BOTULISM in humans, wild fowl, HORSES; and CATTLE. Seven subtypes (sometimes called antigenic types, or strains) exist, each producing a different botulinum toxin (BOTULINUM TOXINS). The organism and its spores are widely distributed in nature.
An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A species of gram-positive bacteria in the family Clostridiaceae, used for the industrial production of SOLVENTS.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Processes involved in the formation of TERTIARY PROTEIN STRUCTURE.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
Chemical, spectroscopic, or microscopic detection of extremely small amounts of blood.
A species of gram-negative, anaerobic, rod-shaped bacteria isolated from the gingival margin and sulcus and from infections of the upper respiratory tract and pleural cavity.
Endoscopic examination, therapy or surgery of the luminal surface of the colon.
A genus of gram-negative, anaerobic, rod-shaped bacteria found in cavities of humans and other animals. No endospores are formed. Some species are pathogenic and occur in various purulent or gangrenous infections.
A benign epithelial tumor with a glandular organization.
Endoscopic examination, therapy or surgery of the sigmoid flexure.
Fatty acid biopolymers that are biosynthesized by microbial polyhydroxyalkanoate synthase enzymes. They are being investigated for use as biodegradable polyesters.
A gram-negative, facultatively chemoautotrophic bacterium, formerly called Wautersia eutropha, found in water and soil.
Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.
A species of gram-negative bacteria in the genus PSEUDOMONAS. It is isolated from oil-water emulsions used as lubricants and cooling agents in the cutting and grinding of materials.
Enzymes from the transferase class that catalyze the transfer of acyl groups from donor to acceptor, forming either esters or amides. (From Enzyme Nomenclature 1992) EC 2.3.
Salts and esters of hydroxybutyric acid.
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
An enzyme that catalyzes the conversion of ATP, L-glutamate, and NH3 to ADP, orthophosphate, and L-glutamine. It also acts more slowly on 4-methylene-L-glutamate. (From Enzyme Nomenclature, 1992) EC 6.3.1.2.
A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.
Biologically active DNA which has been formed by the in vitro joining of segments of DNA from different sources. It includes the recombination joint or edge of a heteroduplex region where two recombining DNA molecules are connected.
A colorless alkaline gas. It is formed in the body during decomposition of organic materials during a large number of metabolically important reactions. Note that the aqueous form of ammonia is referred to as AMMONIUM HYDROXIDE.
An enzyme that catalyzes the formation of 2 molecules of glutamate from glutamine plus alpha-ketoglutarate in the presence of NADPH. EC 1.4.1.13.
Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a virus, transplanting whole nuclei, transplanting cell hybrids, etc.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The condition that results from excessive loss of water from a living organism.
Inorganic compounds that contain uranium as an integral part of the molecule.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
The systematic study of the complete complement of proteins (PROTEOME) of organisms.
A species of gram-positive, coccoid bacteria whose organisms are normal flora of the intestinal tract. Unlike ENTEROCOCCUS FAECALIS, this species may produce an alpha-hemolytic reaction on blood agar and is unable to utilize pyruvic acid as an energy source.
A genus of gram-positive, coccoid bacteria consisting of organisms causing variable hemolysis that are normal flora of the intestinal tract. Previously thought to be a member of the genus STREPTOCOCCUS, it is now recognized as a separate genus.
Nonsusceptibility of bacteria to the action of VANCOMYCIN, an inhibitor of cell wall synthesis.
The smallest continent and an independent country, comprising six states and two territories. Its capital is Canberra.
Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

Transfer of vancomycin resistance transposon Tn1549 from Clostridium symbiosum to Enterococcus spp. in the gut of gnotobiotic mice. (1/4)

The vancomycin resistance vanB2 gene cluster is disseminated worldwide and has been found in phylogenetically remote bacterial genera. The vanB2 operon is part of conjugative transposons Tn1549/Tn5382, but conjugative transposition of these elements has not been demonstrated. We have obtained transfer of a Tn1549-like element (referred to herein as "Tn1549-like") from Clostridium symbiosum MLG101 to Enterococcus faecium 64/3 and Enterococcus faecalis JH2-2 in the digestive tract of gnotobiotic mice and to E. faecium 64/3 in vitro. Retransfer of Tn1549-like from an E. faecium transconjugant also containing Tn916 to E. faecium BM77 was obtained in vitro, albeit at a very low frequency. Transfer efficiency was found to be both donor and recipient dependent. Pulsed-field gel electrophoresis analysis of total SmaI-digested DNA of 48 transconjugants indicated in 27 instances the acquisition of ca. 34 kb of DNA. Two transconjugants harbored two copies of the transposon. Sequencing of the flanking regions of Tn1549-like in 48 transconjugants revealed 29 integration events in 26 loci in the E. faecium genome, and two hot spots for insertion were identified. Integration of the transposon was associated with the acquisition of 5 (n = 18) or 6 (n = 7) bp of donor DNA or with 5-bp duplications of target DNA in the remaining transconjugants. These data demonstrate functionality of the Tn1549-like element and attest that the transfer of the vanB operon between enterococci and human commensal anaerobes occurs in the intestinal environment.  (+info)

Homotropic allosteric control in clostridial glutamate dehydrogenase: different mechanisms for glutamate and NAD+? (2/4)

 (+info)

An asymmetric model for Na+-translocating glutaconyl-CoA decarboxylases. (3/4)

 (+info)

Analysis of the mobilization functions of the vancomycin resistance transposon Tn1549, a member of a new family of conjugative elements. (4/4)

 (+info)

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SWISS-MODEL Repository entry for A0RTP4 (PDXT_CENSY), Pyridoxal 5-phosphate synthase subunit PdxT. Cenarchaeum symbiosum (strain A)
CYPMHS is used as a term for all services that work with children and young people who have difficulties with their emotional or behavioural wellbeing.
To search for genetic clues to carbon and energy metabolism in Crenarchaeota, the researchers extracted C. symbiosum DNA from its host sponge and constructed a DNA library for sequencing the symbiont s genome. Hallam et al. then searched for representative genes linked to pathways associated with autotrophic carbon assimilation. They found many components of two pathways: the 3-hydroxypropionate cycle and the reductive tricarboxylic acid (citric acid) pathway (TCA). Both cycles involve a multistep series of chemical reactions that convert inorganic compounds in this case, carbon dioxide into organic carbon molecules. Though some components of the 3-hydroxypropionate cycle were missing in C. symbiosum, enough elements (including core proteins) were found to support a modified version of this pathway for carbon assimilation, using carbon dioxide ...
Terpenoids, also known as isoprenoids, are a large class of natural products consisting of isoprene (C5) units. There are two biosynthetic pathways, the mevalonate pathway [MD:M00095] and the non-mevalonate pathway or the MEP/DOXP pathway [MD:M00096], for the terpenoid building blocks: isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). The action of prenyltransferases then generates higher-order building blocks: geranyl diphosphate (GPP), farsenyl diphosphate (FPP), and geranylgeranyl diphosphate (GGPP), which are the precursors of monoterpenoids (C10), sesquiterpenoids (C15), and diterpenoids (C20), respectively. Condensation of these building blocks gives rise to the precursors of sterols (C30) and carotenoids (C40). The MEP/DOXP pathway is absent in higher animals and fungi, but in green plants the MEP/DOXP and mevalonate pathways co-exist in separate cellular compartments. The MEP/DOXP pathway, operating in the plastids, is responsible for the formation of essential oil ...
Klasifikace archeí je i dnes neustále v pohybu. Současné systémy se snaží seskupovat organismy na základě jejich skutečné příbuznosti.[13] Velkou roli v systematice hrají sekvence genů pro ribozomální RNA, díky nimž lze příbuzenské vztahy odhalit.[14] Většina z těch nejznámějších archeí se dnes řadí do dvou kmenů, Euryarchaeota a Crenarchaeota. Přesto existují a jsou nadále objevovány i další kmeny, například druh Nanoarchaeum equitans, objevený v roce 2003, je klasifikován v samostatném kmeni Nanoarchaeota.[15] Pro hrstku neobvyklých termofilních archeí se zase zavedl kmen Korarchaeota.[16][17] Podobně byl pro druhy Nitrosopumilus maritimus, Cenarchaeum symbiosum a příbuzná mezofilní archaea zaveden kmen Thaumarchaeota.[18] Sekvenování archeálních genomů přineslo objevy dalších odlišných linií: V roce 2011 byl navržen nový kmen Aigararchaeota pro archeum Caldiarchaeum subterraneum, nalezené v geotermálních vodách v podzemním ...
This project is supported by the Canadian Institutes of Health Research, Canada Foundation for Innovation, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Canada, Genome Alberta, and Genome British Columbia, a not-for-profit organization that is leading Canadas national genomics strategy with $900 million in funding from the federal government ...
This project is supported by the Canadian Institutes of Health Research, Canada Foundation for Innovation, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Canada, Genome Alberta, and Genome British Columbia, a not-for-profit organization that is leading Canadas national genomics strategy with $900 million in funding from the federal government ...
And Clostridium symbiosum (Stevens) comb. Nov". International Journal of Systematic Bacteriology. 26 (2): 195. doi:10.1099/ ... "Clostridium clostridioforme: Clostridium clostridioforme corrig. (Burri and Ankersmit 1906) Kaneuchi et al. 1976". National ... While Clostridium species have cell walls that resemble gram-positive bacteria, E. clostridioformis often appears negative by ... In subsequent years, these bacteria were shown to form spores, causing them to be reclassified in the genus Clostridium. Most ...
In maize, it is closer to the C-terminal, while in Clostridium symbiosum, it is closer to the N-terminal. Research has shown ... and the bacteria Clostridium symbiosum (P22983; as well as other bacteria). In those two organisms PPDK functions similarly to ... UniProt 50%-90% clusters: From Clostridium PPDK Stephen P, Vijayan R, Bhat A, Subbarao N, Bamezai RN (September 2008). " ... symbiosum protein, PDB: 1KBL, 1KC7​). PPDK is used in the C4 pathway, to improve the efficiency of carbon dioxide fixation. In ...
... symbiosum Clostridium tagluense Clostridium tarantellae Clostridium tepidiprofundi Clostridium termitidis Clostridium tertium ... Clostridium aceticum Clostridium acetireducens Clostridium acetobutylicum Clostridium acidisoli Clostridium aciditolerans ... Clostridium acidurici Clostridium aerotolerans Clostridium aestuarii Clostridium akagii Clostridium aldenense Clostridium ... difficile Clostridium diolis Clostridium disporicum Clostridium drakei Clostridium durum Clostridium estertheticum Clostridium ...
Clostridium symbiosum MeSH B03.300.390.400.200.722 - Clostridium tertium MeSH B03.300.390.400.200.725 - Clostridium tetani MeSH ... Clostridium symbiosum MeSH B03.510.415.400.200.722 - Clostridium tertium MeSH B03.510.415.400.200.725 - Clostridium tetani MeSH ... Clostridium botulinum type G MeSH B03.300.390.400.200.180 - Clostridium butyricum MeSH B03.300.390.400.200.200 - Clostridium ... Clostridium botulinum type G MeSH B03.510.415.400.200.180 - Clostridium butyricum MeSH B03.510.415.400.200.200 - Clostridium ...
The gene encoding the NAD(+)-dependent glutamate dehydrogenase (GDH) of Clostridium symbiosum was cloned using the polymerase ... The glutamate dehydrogenase gene of Clostridium symbiosum. Cloning by polymerase chain reaction, sequence analysis and over- ...
Zum Mechanismus der 2-Hydroxyglutaryl-CoA Dehydratase aus Clostridium symbiosum Das 2-Hydroxyglutaryl-CoA-Dehydratase-System ... Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum by: Parthasarathy, Anutthaman ... Die Reinigungsmethoden für Komponente D aus Clostridium symbiosum wurden weiter verbessert und erneute Charakterisierungen der ... CO2 und H2 durch Clostridium symbiosum und Acidaminococcus fermentans. Die Dehydratase katalysiert die syn-Dehydratisierung von ...
Clostridium] symbiosum). Find diseases associated with this biological target and compounds tested against it in bioassay ...
Direct sub-taxa of Clostridium symbiosum: Clostridium symbiosum ATCC 14940, Clostridium symbiosum WAL-14163, Clostridium ... Clostridium symbiosum. RANK: Species TAXONOMY: Terrabacteria group -> Firmicutes -> Clostridia -> Clostridiales -> ... Antimicrob Agents Chemother 50:1054-1062]We describe a fatal case of Clostridium symbiosum bacteremia in a 70-year-old man with ... The database ranks the pathogenicity of species on a scale of 1 to 4. Clostridium symbiosum ranks on this scale: ...
The partial amino acid sequence of the NAD -dependent glutamate dehydrogenase of Clostridium symbiosum: implications for the ...
clostridium] symbiosum EC#: 2.7.9.1 IUBMB Gene Name(s): ppdK Metabolic Pathways ...
Using directed microbial culture techniques, we discovered Clostridium immunis, a previously unknown bacterial species from ... Clostridium immunis, a previously unknown bacterial species from this family, protects against the development of colitis. This ... and Clostridium symbiosum (Stevens) comb. nov. Int. J. Syst. Evol. Microbiol. 26, 195-204 (1976) ... Clostridium immunis, a previously unknown bacterial species from this family, protects against the development of colitis. This ...
And Clostridium symbiosum (Stevens) comb. Nov". International Journal of Systematic Bacteriology. 26 (2): 195. doi:10.1099/ ... "Clostridium clostridioforme: Clostridium clostridioforme corrig. (Burri and Ankersmit 1906) Kaneuchi et al. 1976". National ... While Clostridium species have cell walls that resemble gram-positive bacteria, E. clostridioformis often appears negative by ... In subsequent years, these bacteria were shown to form spores, causing them to be reclassified in the genus Clostridium. Most ...
Species: Clostridium symbiosum [TaxId:1512]. Gene: PPDK. Database cross-references and differences (RAF-indexed): *Uniprot ...
Transfer of vancomycin resistance transposon Tn1549 from Clostridium symbiosum to Enterococcus spp. in the gut of gnotobiotic ...
Transfer of vancomycin resistance transposon Tn1549 from Clostridium symbiosum to Enterococcus spp. in the gut of gnotobiotic ... tISCpe8, an IS1595-family lincomycin resistance element located on a conjugative plasmid in Clostridium perfringens. ... A Phenotypically Silent vanB2 Operon Carried on a Tn1549-Like Element in Clostridium difficile. ...
Rice DW, Hornby DP & Engel PC (1985) Crystallization of an NAD+-dependent glutamate dehydrogenase from Clostridium symbiosum.. ... HORNBY DP (1987) ISOLATION OF 3 COMPONENTS OF THE HYDROXYGLUTARATE PATHWAY FROM CLOSTRIDIUM-SYMBIOSUM. BIOCHEM SOC T. , 15(6), ... Rice DW, Baker PJ, Farrants GW & Hornby DP (1987) The crystal structure of glutamate dehydrogenase from Clostridium symbiosum ... Site and significance of chemically modifiable cysteine residues in glutamate dehydrogenase of Clostridium symbiosum and the ...
Nevertheless, some anaerobic bacteria, such as Acidaminococcus fermentans and Clostridium symbiosum, catalyze this reaction in ... 2-Hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum. Eur. J. Biochem. 265:404-414. ... symbiosum. E. coli BL21(DE3) was transformed with the plasmids pID-3 and pID-4, resulting in the new recombinant strain E. coli ... symbiosum (11). The new pathway diverts from central metabolism at 2-oxoglutarate (Fig. 1). ...
Fecal Clostridium symbiosum for Noninvasive Detection of Early and Advanced Colorectal Cancer: Test and Validation Studies. ...
Current antimicrobial susceptibilities among the clostridia are also presented, as are the evaluation, interpretation, and ... Severe infections caused by Clostridium species have been described in the medical literature for centuries-largely because of ... Bacteremia caused by Clostridium symbiosum. J Clin Microbiol 42:4390-4392.. 159. Hausmann R,, Albert F,, Geissdörfer W,, Betz P ... Clostridium innocuum, and Clostridium ramosum compared with those of clinical isolates of Clostridium perfringens. J Clin ...
1992) 112:52-56), Clostridium symbiosum (Teller et al., Eur. J. Biochem. (1992) 206: 151-159), Synechocystis (Plant Mol. Biol ... Alternatively, these genes can be isolated from other Clostridium species such as C. aminobulyricum. Although E. coli does have ... The gene encoding a 4-hydroxybutyryl CoA transferase gene from the Gram-positive, strict anaerobic bacterium Clostridium ... 4) has been characterized in Clostridium kluyveri (Sohling and Gottschalk, 1993, Eur. J. Biochem. 212, 121-127; Wolffet al., ...
Glutamate dehydrogenase of Clostridium symbiosum : another example of an abrupt transition in the kinetic plots Biochem Soc ...
Zum Mechanismus der 2-Hydroxyglutaryl-CoA Dehydratase aus Clostridium symbiosum by: Hetzel, Marc Published: (2004) ... On the enzymatic mechanism of 2-hydroxyisocaproyl-CoA dehydratase from Clostridium difficile by: Kim Ji-Hoe Published: (2004) ... On the enzymatic mechanism of 4-hydroxybutyryl-CoA dehydratase and 4-hydroxybutyrate CoA-transferase from Clostridium ...
In maize, it is closer to the C-terminal, while in Clostridium symbiosum, it is closer to the N-terminal. Research has shown ... and the bacteria Clostridium symbiosum (P22983; as well as other bacteria). In those two organisms PPDK functions similarly to ... UniProt 50%-90% clusters: From Clostridium PPDK Stephen P, Vijayan R, Bhat A, Subbarao N, Bamezai RN (September 2008). " ... symbiosum protein, PDB: 1KBL, 1KC7​). PPDK is used in the C4 pathway, to improve the efficiency of carbon dioxide fixation. In ...
Transfer of vancomycin resistance transposon Tn1549 from Clostridium symbiosum to Enterococcus spp. in the gut of gnotobiotic ... Notably, a Tn1549 sequence obtained from Clostridium spp. of another Australian patient was identical to Tn1549 of a subset of ... Characterization of a Tn5382-like transposon containing the vanB2 gene cluster in a Clostridium strain isolated from human ... Interestingly, Tn1549-vanB is not restricted to enterococci but was also detected among anaerobic bacilli such as Clostridium ...
Clostridium symbiosum. ATCC 14940. Csy. PRJNA18183 Clostridium hylemonae. DSM 15053. Chy. PRJNA30369 ... Clostridium asparagiforme. Cas. Ruminococcus sp. 5_1_39BFAA. Rsp. Fusobacterium sp. oral taxon 370. Fsp. Streptococcus mutans. ... animalis) or more oxidizing (Clostridium hylemonae, Porphyromonas asaccharolytica) regions, while the proteins from bacteria ...
Crystal structure of a probable RNA-binding protein from Clostridium symbiosum ATCC 14940. ...
... dependent glutamate dehydrogenase of Clostridium symbiosum Biochem Soc Trans (October,1988) ...
Construction of a dimeric form of glutamate dehydrogenase from clostridium symbiosum by site-directed mutagenesis. Biochimica ...
Transfer of vancomycin resistance transposon Tn1549 from Clostridium symbiosum to Enterococcus spp. in the gut of gnotobiotic ... 23375705 - Preoperative risk factors for postoperative clostridium difficile infection in colectom.... 23595915 - Medication ... The vanB gene is known to be present in commensal enteric bacteria such as Clostridium, and transmission of this gene to E. ... although the vanB gene appears to be common in commensal bacteria including Clostridium spp [7-9]. ...
Effect of additives on crystallization of glutamate dehydrogenase from Clostridium symbiosum: evidence for a ligandinduced ...
... and Clostridium symbiosum (177 genes) (see online supplementary table S20). At the species level, P. micra was enriched in CRC ... Clostridium septicum aortitis: Report of two cases and review of the literature. J Vasc Surg 2009;49:1304-9. doi:10.1016/j.jvs. ... reported associations between CRC and clinical infections by specific bacteria such as Streptococcus bovis12 and Clostridium ...
Alteration of the quaternary structure of glutamate dehydrogenase from Clostridium symbiosum by a single mutation distant from ...
Transfer of vancomycin resistance transposon Tn1549 from Clostridium symbiosum to Enterococcus spp. in the gut of gnotobiotic ... Characterization of a Tn5382-like transposon containing the vanB2 gene cluster in a Clostridium strain isolated from human ... Genetic organization and distribution of tetracycline resistance determinants in Clostridium perfringens. Antimicrob. Agents ...
0544 was more similar to the characterized activator subunits from Clostridia symbiosum [33] and Acidaminococcus fermentans [34 ... 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum. Eur J Biochem. 1999;265:404-414. doi: 10.1046/j.1432-1327.1999. ... Closest homologs to these genes were found in a variety of species including Clostridia, gamma Proteobacteria, and ... and with a variety of uncharacterized proteins from Clostridia and other species (Figure ​(Figure22). ...
  • The glutamate dehydrogenase gene of Clostridium symbiosum. (nih.gov)
  • The gene encoding the NAD(+)-dependent glutamate dehydrogenase (GDH) of Clostridium symbiosum was cloned using the polymerase chain reaction (PCR) because it could not be recovered by standard techniques. (nih.gov)
  • Nevertheless, some anaerobic bacteria, such as Acidaminococcus fermentans and Clostridium symbiosum , catalyze this reaction in five steps during the fermentation of glutamate to ammonia, CO 2 , acetate, butyrate, and molecular hydrogen ( 7 ). (asm.org)
  • Construction of a dimeric form of glutamate dehydrogenase from clostridium symbiosum by site-directed mutagenesis. (mpg.de)
  • Alteration of the quaternary structure of glutamate dehydrogenase from Clostridium symbiosum by a single mutation distant from the subunit interfaces. (mpg.de)
  • Using directed microbial culture techniques, we discovered Clostridium immunis , a previously unknown bacterial species from this family, that-when administered to colitis-prone mice-protected them against colitis-associated death. (nature.com)
  • While Clostridium species have cell walls that resemble gram-positive bacteria, E. clostridioformis often appears negative by Gram stain. (wikipedia.org)
  • Severe infections caused by Clostridium species have been described in the medical literature for centuries-largely because of their fulminant nature, distinctive clinical presentations, and complex management issues. (asmscience.org)
  • Several fecal bacterial species that were different between autologous and allogenic FMT have been linked to human metabolism," including Lactobacillus salivarius, Butyrivibrio, Clostridium symbiosum and Eubacterium, Nieuwdorp and colleagues wrote. (healio.com)
  • After a storage period at 4 °C for eight weeks, meat juice from all samples was processed for culturing, DNA extraction and SYBR green qPCR for Clostridium species. (bvsalud.org)
  • With some samples being co-contaminated with two different species, 53% (n = 32) of all investigated vacuum-packed beef samples were found to be positive for cold-tolerant clostridia. (bvsalud.org)
  • Bacterial species belonging to the genus Clostridium have been recognized as causative agents of blown pack spoilage (BPS) in vacuum packed meat products. (bvsalud.org)
  • Comparative genome analyses have provided insight into the genomic diversity and physiology of these bacteria and divides clostridia into two separate species clusters. (bvsalud.org)
  • It is an invaluable non-invasive diagnostic tool to objectively evaluate your microbiome health including Clostridium species, pathogenic bacteria, yeast/fungus and parasites. (labtests.eu)
  • Type species of the genus CLOSTRIDIUM, a gram-positive bacteria in the family Clostridiaceae. (bvsalud.org)
  • 1982), this species is an earlier heterotypic synonym of Clostridium perenne (Prévot 1940) McClung and McCoy 1957 (Approved Lists 1980) . (dsmz.de)
  • To convert E scherichia coli into a glutaconate producer, we expressed six genes in this organism encoding 2-hydroxyglutarate dehydrogenase (HgdH) ( 14 ), glutaconate CoA-transferase (GctAB) ( 13 ), and the activator of the dehydratase (HgdC) from A. fermentans ( 10 ), as well as 2-hydroxyglutaryl-CoA dehydratase (HgdAB) from C. symbiosum ( 11 ). (asm.org)
  • Model based on crystal structures of PPDK from Clostridium symbiosum in the 2 extreme conformational states shown to the left and of complexes bound to substrate analogs, phosphonopyruvate and 5'-adenylyl-β,γ-imidodiphosphate (AMPPNP). (proteopedia.org)
  • Intestinal anaerobic bacteria such as Enterococcus gilvus, Clostridium symbiosum and Eubacterium rectale strains also express transaldolase-pathway gene clusters during fermentative growth with SQ. The now three known biochemical strategies for SQ catabolism reflect adaptations to the aerobic or anaerobic life-style of the different bacteria. (univie.ac.at)
  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC516307/]Synonyms : JCM 1297, DSM 934, Clostridium symbiosum, Bacteroides symbiosus, ATCC. (datapunk.net)
  • Furthermore, chronic gut infections with recognised, specific pathogens such as Clostridium difficile, Yersinia enterocolitica or Campylobacter jejuni/coli are generally not eradicated with antibiotics. (justia.com)
  • Fungal agents such as Sacchromyces boulardii have been used to treat, albeit inefficiently, Clostridium difficile infection and Lactobacillus GG has also been used for this purpose (Floch M. Probiotics and Dietary Fibre. (justia.com)
  • Various patents have claimed the use of probiotics for narrow disease conditions including treatment of Clostridium difficile with a combination of Vancomycin and butyric acid bacteria (U.S. Pat. (justia.com)
  • Clostridium clostridioforme: Clostridium clostridioforme corrig. (wikipedia.org)
  • Launay A, Ballard SA, Johnson PD, Grayson ML, Lambert T (2006) Transfer of vancomycin resistance transposon Tn1549 from Clostridium symbiosum to Enterococcus spp. (datapunk.net)
  • Das 2-Hydroxyglutaryl-CoA-Dehydratase-System ist das Schlüsselenzym in der Fermentation von Glutamat zu Acetat, Butyrat, CO2 und H2 durch Clostridium symbiosum und Acidaminococcus fermentans. (uni-marburg.de)
  • A second plasmid, pID-4, derived from the pASK-IBA3plus vector, harbors the genes of the activator of 2-hydroxyglutaryl-CoA dehydratase ( hgdC ) from A. fermentans and 2-hydroxyglutaryl-CoA dehydratase ( hgdAB ) from C. symbiosum . (asm.org)
  • Alaska E43, and Clostridium thermocellum DSM 1313) in T2DM patients. (wmflabs.org)
  • Clostridiiformis (Burri and Ankersmit) Holdeman and Moore and of Related Organisms: Proposal of Clostridium clostridiiformis (Burri and Ankersmit) comb. (wikipedia.org)
  • and an almost complete absence of buk genes.Two patients were greatly enriched in buk genes similar to those of Clostridium butyricum and C. perfringens , whereas a fourthpatient displayed abundant communities containing both genes. (biomedcentral.com)
  • Moreover, it was also revealed that Clostridium symbiosum and Ruminococcus gnavus might be used as therapeutic agent for ameliorating growth abnormalities in malnourished children. (bvsalud.org)
  • Clostridium beijerinckii NCIMB 8052, Clostridium sp. (wmflabs.org)
  • Lactobacillus gasseri JV-V03, Lactobacillus gasser i SJ-9E-US, Lactobacillus gasseri 202-4, and Lactobacillus salivarius ACS-116-V-Col5a) and a decrease in Clostridium spp. (wmflabs.org)
  • The present invention relates to pharmaceutical compositions suitable for the treatment of chronic diseases associated with the presence of abnormal or an abnormal distribution of microflora in the gastrointestinal tract of a mammalian host, which compositions comprise viable non-pathogenic or attenuated pathogenic Clostridia. (justia.com)
  • Clostridium baratii corrig. (dsmz.de)
  • Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota. (nature.com)
  • The 16S rRNA gene sequence showed a 99.4% identity with C. symbiosum. (bvsalud.org)
  • After that, a previously developed multiplex qPCR, sequence analysis of the 16S rRNA gene, and MALDI-TOF MS were applied in order to identify Clostridium spp. (bvsalud.org)
  • Whole-genome sequencing of six New Zealand psychrotolerant clostridia isolates derived from three meat production animal types and their environments was performed to examine their roles in BPS. (bvsalud.org)
  • In subsequent years, these bacteria were shown to form spores, causing them to be reclassified in the genus Clostridium. (wikipedia.org)
  • The transfer of blown pack spoilage causing Clostridium spores from the farm to the meat plant is of growing concern to the meat industry. (bvsalud.org)
  • later subjective synonyms of Clostridium barati . (dsmz.de)
  • Comparison of the amino-terminal sequence with those of E. coli, S. typhimurium and Clostridium symbiosum revealed only 39% amino acid homologies. (illinois.edu)
  • Current antimicrobial susceptibilities among the clostridia are also presented, as are the evaluation, interpretation, and reporting of clinical microbiology laboratory results. (asmscience.org)
  • To our knowledge, this represents the first report of C. symbiosum isolation in Korea. (bvsalud.org)
  • Antimicrob Agents Chemother 50:1054-1062]We describe a fatal case of Clostridium symbiosum bacteremia in a 70-year-old man with metastatic colon cancer. (datapunk.net)
  • Clostridium symbiosum was isolated from the blood of a 61-year-old immunocompromised woman who had diagnosed ovarian cancer with multiple metastases and who had developed persistent tachycardia. (bvsalud.org)
  • This study investigated the environmental niches of these Clostridium spp. (bvsalud.org)