Clostridium sticklandii: A species of gram-positive, anaerobic bacteria in the family Clostridiaceae frequently used for the study of ENZYMES.Clostridium: A genus of motile or nonmotile gram-positive bacteria of the family Clostridiaceae. Many species have been identified with some being pathogenic. They occur in water, soil, and in the intestinal tract of humans and lower animals.Amino Acid Oxidoreductases: A class of enzymes that catalyze oxidation-reduction reactions of amino acids.CobamidesOrnithine: An amino acid produced in the urea cycle by the splitting off of urea from arginine.Selenium: An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.Clostridium difficile: A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.Clostridium Infections: Infections with bacteria of the genus CLOSTRIDIUM.Clostridium botulinum: A species of anaerobic, gram-positive, rod-shaped bacteria in the family Clostridiaceae that produces proteins with characteristic neurotoxicity. It is the etiologic agent of BOTULISM in humans, wild fowl, HORSES; and CATTLE. Seven subtypes (sometimes called antigenic types, or strains) exist, each producing a different botulinum toxin (BOTULINUM TOXINS). The organism and its spores are widely distributed in nature.Peptostreptococcus: A genus of gram-positive, anaerobic, coccoid bacteria that is part of the normal flora of humans. Its organisms are opportunistic pathogens causing bacteremias and soft tissue infections.Pyrroline Carboxylate Reductases: A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 1.5.1.1) and the 5-oxidoreductase (EC 1.5.1.2). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.Enterocolitis, Pseudomembranous: An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.Clostridium acetobutylicum: A species of gram-positive bacteria in the family Clostridiaceae, used for the industrial production of SOLVENTS.Peer Group: Group composed of associates of same species, approximately the same age, and usually of similar rank or social status.Video Games: A form of interactive entertainment in which the player controls electronically generated images that appear on a video display screen. This includes video games played in the home on special machines or home computers, and those played in arcades.Videotape Recording: Recording of visual and sometimes sound signals on magnetic tape.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Peer Review, Research: The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.Peer Review: An organized procedure carried out by a select committee of professionals in evaluating the performance of other professionals in meeting the standards of their specialty. Review by peers is used by editors in the evaluation of articles and other papers submitted for publication. Peer review is used also in the evaluation of grant applications. It is applied also in evaluating the quality of health care provided to patients.Trifolium: A plant genus of the family FABACEAE.Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.Phytoestrogens: PLANT EXTRACTS and compounds, primarily ISOFLAVONES, that mimic or modulate endogenous estrogens, usually by binding to ESTROGEN RECEPTORS.Humulus: A plant genus in the CANNABACEAE family. Best known for the buds of Humulus lupulus L. used in BEER.Isoflavones: 3-Phenylchromones. Isomeric form of FLAVONOIDS in which the benzene group is attached to the 3 position of the benzopyran ring instead of the 2 position.Tombusviridae: A family of RNA plant viruses infecting dicotyledons. Transmission is mainly by mechanical inoculation and through propagative plant material. All species elicit formation of multivesicular inclusion bodies. There are at least eight genera: Aureusvirus, Avenavirus, CARMOVIRUS, Dianthovirus, Machlomovirus, Necrovirus, Panicovirus, and TOMBUSVIRUS.Prostate: A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.RNA, Transfer: The small RNA molecules, 73-80 nucleotides long, that function during translation (TRANSLATION, GENETIC) to align AMINO ACIDS at the RIBOSOMES in a sequence determined by the mRNA (RNA, MESSENGER). There are about 30 different transfer RNAs. Each recognizes a specific CODON set on the mRNA through its own ANTICODON and as aminoacyl tRNAs (RNA, TRANSFER, AMINO ACYL), each carries a specific amino acid to the ribosome to add to the elongating peptide chains.Amino Acyl-tRNA Synthetases: A subclass of enzymes that aminoacylate AMINO ACID-SPECIFIC TRANSFER RNA with their corresponding AMINO ACIDS.Appendix: A worm-like blind tube extension from the CECUM.BooksHistory, 19th Century: Time period from 1801 through 1900 of the common era.tRNA Methyltransferases: Enzymes that catalyze the S-adenosyl-L-methionine-dependent methylation of ribonucleotide bases within a transfer RNA molecule. EC 2.1.1.History, 17th Century: Time period from 1601 through 1700 of the common era.ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Databases, Protein: Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Sequence Analysis, Protein: A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.Intramolecular Transferases: Enzymes of the isomerase class that catalyze the transfer of acyl-, phospho-, amino- or other groups from one position within a molecule to another. EC 5.4.Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Biochemical Processes: Chemical reactions or functions, enzymatic activities, and metabolic pathways of living things.Molecular Biology: A discipline concerned with studying biological phenomena in terms of the chemical and physical interactions of molecules.Laboratories: Facilities equipped to carry out investigative procedures.Systems Biology: Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.Biology: One of the BIOLOGICAL SCIENCE DISCIPLINES concerned with the origin, structure, development, growth, function, genetics, and reproduction of animals, plants, and microorganisms.England

Coexpression, purification and characterization of the E and S subunits of coenzyme B(12) and B(6) dependent Clostridium sticklandii D-ornithine aminomutase in Escherichia coli. (1/6)

D-Ornithine aminomutase from Clostridium sticklandii comprises two strongly associating subunits, OraS and OraE, with molecular masses of 12,800 and 82,900 Da. Previous studies have shown that in Escherichia coli the recombinant OraS protein is synthesized in the soluble form and OraE as inclusion bodies. Refolding experiments also indicate that the interactions between OraS and OraE and the binding of either pyridoxal phosphate (PLP) or adenosylcobalamin (AdoCbl) play important roles in the refolding process. In this study, the DNA fragment containing both genes was cloned into the same expression vector and coexpression of the oraE and oraS genes was carried out in E. coli. The solubility of the coexpressed OraS and OraE increases with decreasing isopropyl thio-beta-D-galactoside induction temperature. Among substrate analogues tested, only 2,4-diamino-n-butyric acid displays competitive inhibition of the enzyme with a K(i) of 96 +/- 14 microm. Lys629 is responsible for the binding of PLP. The apparent K(d) for coenzyme B(6) binding to d-ornithine aminomutase is 224 +/- 41 nm as measured by equilibrium dialysis. The mutant protein, OraSE-K629M, is successfully expressed. It is catalytically inactive and unable to bind PLP. Because no coenzyme is involved in protein folding during in vivo translation of OraSE-K629M in E. coli, in vitro refolding of the enzyme employs a different folding mechanism. In both cases, the association of the S and E subunit is important for D-ornithine aminomutase to maintain an active conformation.  (+info)

A locking mechanism preventing radical damage in the absence of substrate, as revealed by the x-ray structure of lysine 5,6-aminomutase. (2/6)

Lysine 5,6-aminomutase is an adenosylcobalamin and pyridoxal-5'-phosphate-dependent enzyme that catalyzes a 1,2 rearrangement of the terminal amino group of dl-lysine and of l-beta-lysine. We have solved the x-ray structure of a substrate-free form of lysine-5,6-aminomutase from Clostridium sticklandii. In this structure, a Rossmann domain covalently binds pyridoxal-5'-phosphate by means of lysine 144 and positions it into the putative active site of a neighboring triosephosphate isomerase barrel domain, while simultaneously positioning the other cofactor, adenosylcobalamin, approximately 25 A from the active site. In this mode of pyridoxal-5'-phosphate binding, the cofactor acts as an anchor, tethering the separate polypeptide chain of the Rossmann domain to the triosephosphate isomerase barrel domain. Upon substrate binding and transaldimination of the lysine-144 linkage, the Rossmann domain would be free to rotate and bring adenosylcobalamin, pyridoxal-5'-phosphate, and substrate into proximity. Thus, the structure embodies a locking mechanism to keep the adenosylcobalamin out of the active site and prevent radical generation in the absence of substrate.  (+info)

The bacterial YbaK protein is a Cys-tRNAPro and Cys-tRNA Cys deacylase. (3/6)

Bacterial prolyl-tRNA synthetases and some smaller paralogs, YbaK and ProX, can hydrolyze misacylated Cys-tRNA Pro or Ala-tRNA Pro. To assess the significance of this quality control editing reaction in vivo, we tested Escherichia coli ybaK for its ability to suppress the E. coli thymidylate synthase thyA:146CCA missense mutant strain, which requires Cys-tRNA(Pro) for growth in the absence of thymine. Missense suppression was observed in a ybaK deletion background, suggesting that YbaK functions as a Cys-tRNA Pro deacylase in vivo. In vitro studies with the full set of 20 E. coli aminoacyl-tRNAs revealed that the Haemophilus influenzae and E. coli YbaK proteins are moderately general aminoacyl-tRNA deacylases that preferentially hydrolyze Cys-tRNA Pro and Cys-tRNA Cys and are also weak deacylases that cleave Gly-tRNA, Ala-tRNA, Ser-tRNA, Pro-tRNA, and Met-tRNA. The ProX protein acted as an aminoacyl-tRNA deacylase that cleaves preferentially Ala-tRNA and Gly-tRNA. The potential of H. influenzae YbaK to hydrolyze in vivo correctly charged Cys-tRNA Cys was tested in E. coli strain X2913 (ybaK+). Overexpression of H. influenzae ybaK decreased the in vivo ratio of Cys-tRNA Cys to tRNA Cys from 65 to 35% and reduced the growth rate of strain X2913 by 30% in LB medium. These data suggest that YbaK-mediated hydrolysis of aminoacyl-tRNA can influence cell growth.  (+info)

Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase. (4/6)

 (+info)

Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. (5/6)

 (+info)

Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence. (6/6)

 (+info)

*Clostridium sticklandii

... shares the highest number of genes that are homologous with Clostridium difficile (a pathogenic species ... sticklandii. One such selenoprotein, glycine reductase A was first identified in Cl. sticklandii. C. sticklandii uses a total ... Clostridium sticklandii is an anaerobic, motile, gram-positive bacterium. It was first isolated in 1954 from the black mud of ... Clostridium sticklandii has a genome that consists of one circular chromosome. On this chromosome are 2,715,461 base pairs. Of ...

*2,4-diaminopentanoate dehydrogenase

Tsuda Y, Friedmann HC (1970). "Ornithine metabolism by Clostridium sticklandii. Oxidation of ornithine to 2-amino-4- ... Stadtman TC (1973). "Lysine metabolism by clostridia. XIIB 2,4-Diaminohexanoate dehydrogenase (2,4-diaminopentanoate ...

*Ornithine racemase

Chen HP, Lin CF, Lee YJ, Tsay SS, Wu SH (2000). "Purification and properties of ornithine racemase from Clostridium sticklandii ...

*Beta-lysine 5,6-aminomutase

V. Some properties of the cobamide coenzyme-dependent beta-lysine mutase of Clostridium sticklandii". Arch. Biochem. Biophys. ...

*Proline racemase

Purification and properties of D-proline reductase and a proline racemase from Clostridium sticklandii". The Journal of ... of proline racemase was first put forward in the late sixties by Cardinale and Abeles using the Clostridium sticklandii enzyme ... Novel proline racemases of medical and veterinary importance were described respectively in Clostridium difficile (Q17ZY4) and ...

*Clostridium aminophilum

Clostridium sticklandii, and Clostridium aminophilum sp. nov". International Journal of Systematic Bacteriology. 43 (1): 107- ... LPSN Clostridium aminophilum at the Encyclopedia of Life Type strain of Clostridium aminophilum at BacDive - the Bacterial ... Clostridium aminophilum is a species of gram-positive ammonia-producing ruminal bacteria, with type strain FT. Paster, B. J.; ... Houlihan AJ, Russell JB (2003). "The susceptibility of ionophore-resistant Clostridium aminophilum F to other antibiotics". J ...

*D-proline reductase (dithiol)

Purification and properties of a D-proline reductase and a proline racemase from Clostridium sticklandii". J. Biol. Chem. 228: ... "Identification of D-proline reductase from Clostridium sticklandii as a selenoenzyme and indications for a catalytically active ...

*D-lysine 5,6-aminomutase

In the early 1950's, 5,6-LAM was discovered in the amino-acid-fermenting bacteria Clostridium sticklandii, in which lysine ... of an adenosine triphosphate regulated B 12-coenzyme-dependent D-alpha-lysine mutase complex from Clostridium sticklandii". ... and formate metabolism in an amino acid fermenting Clostridium". Journal of Bacteriology. 67 (6): 651-7. PMC 357300 . PMID ...

*Betaine reductase

... of the proproteins GrdE of protein B of glycine reductase and PrdA of D-proline reductase from Clostridium sticklandii: ...

*List of MeSH codes (B03)

Clostridium sordellii MeSH B03.300.390.400.200.710 --- Clostridium sticklandii MeSH B03.300.390.400.200.713 --- Clostridium ... Clostridium sordellii MeSH B03.510.415.400.200.710 --- Clostridium sticklandii MeSH B03.510.415.400.200.713 --- Clostridium ... Clostridium butyricum MeSH B03.300.390.400.200.200 --- Clostridium cellulolyticum MeSH B03.300.390.400.200.205 --- Clostridium ... clostridium difficile MeSH B03.300.390.400.200.412 --- Clostridium histolyticum MeSH B03.300.390.400.200.493 --- Clostridium ...
Unit I. Protein structure and function. Amino acids ; Structure of proteins ; Globular proteins ; Fibrous proteins ; Enzymes -- Unit II. Bioenergetics and carbohydrate metabolism. Bioenergetics and oxidative phosphorylation ; Introduction to carbohydrates ; Introduction to metabolism and glycolysis ; Tricarboxylic acid cycle and pyruvate dehydrogenase complex ; Gluconeogenesis ; Glycogen metabolism ; Metabolism of monosaccharides and disaccharides ; Pentose phosphate pathway and nicotinamide adenine dinucleitide phosphate ; Glycosaminoglycans, proteoglycans, and glycoproteins -- Unit III. Lipid metabolism. Dietary lipid metabolism ; Fatty acid, ketone body, and triacylglycerol metabolism ; Phospholipid, glycosphingolipid, and eicosanoid metabolism -- Unit IV. Nitrogen metabolism. Amino acids : Disposal of nitrogen ; Amino acid degradation and synthesis ; Conversion of amino acids to specialized products ; Nucleotide metabolism -- Unit V. Integration of metabolism. Metabolic effects of insulin ...
Results High FPG mothers had a metabolic profile consistent with insulin resistance including higher triglycerides, 3-hydroxybutyrate, and amino acids including alanine, proline and branched chain amino acids (false discovery rate (FDR)-adjusted p,0.05). Lower 1,5-anhydroglucitol in high FPG mothers suggested recent hyperglycemic excursions (FDR-adjusted p,0.05). Pathway analyses indicated differences in amino acid degradation pathways for the two groups (FDR-adjusted p,0.05), consistent with population-based findings in non-pregnant populations. Exploratory analyses with newborn outcomes indicated positive associations for maternal triglycerides with neonatal sum of skinfolds and cord C-peptide and a negative association between maternal glycine and cord C-peptide (p,0.05). ...
Drostanolone (INN; also known as dromostanolone or Drolban), marketed as Masteron, is an anabolic steroid. Drostanolone is a part of thedihydrotestosterone (DHT) family. Its main medical uses include lowering cholesterol levels and as an antineoplastic agent in the treatment of some cancers. It is most commonly marketed as the ester drostanolone propionate (trade name Masteron).. Drostanolone binds to a receptor and activates a cascade of genetic changes, which increases the protein synthesis (anabolism) and decreases the amino acids degradation (catabolism). Other effects of Drostanolone are reduction or inhibition of prolactin or estrogen receptors, which are linked to its anti tumor properties. ...
TestAmerica Sacramento implemented the TOP assay as a solution to this complex problem. The TOP assay rapidly converts polyfluorinated PFAA precursors into PFAAs including PFOA, using a hydroxyl radical-based chemical oxidation method. The TOP assay replicates what micro-organisms in the environment would achieve after many years. The end result is to provide a range of PFAAs which are detectable by LCMSMS[1]. The TOP assay quantifies the sum of PFAS that could be converted to PFAAs in the environment. The TOP methodology has revealed that for AFFF-impacted sites, the existing analytical LCMSMS methods are only detecting an estimated 30% to 50% of the total PFAA mass present as PFAA precursors. ...
Business search by category in Waterproof 71375,Louisiana, United States. ZIPCode2Business allows you to find a business in over 800 business categories.
Kanjee at al. solved the Lcd1 x-ray strucutre, and the protein turned out to be in complex with ppGpp. Enzymatic assays showed that ppGpp inhibits Lcd1, thus providing a link between the acid and stringent responses: these two are in a sense are mutually exclusive. During the stringent response ppGpp alters RNA Polymerase in such a way that genes involved in amino acid biosynthesis are predominantly transcribed, and during the acid stress response Lcd1 degrades lysine. Inhibition of Ldl1 by ppGpp stops amino acid degradation, shifting the balance even more towards the amino acid production ...
Histidylhistidine is a dipeptide composed of two histidine residues. It is an incomplete breakdown product of protein digestion or protein catabolism. Dipeptides are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Some dipeptides are known to have physiological or cell-signalling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis ...
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a novel class of natural products including several antibiotics and bacterial toxins. In countless RiPP biosynthetic pathways, cobalamin-dependent radical SAM (B12/rSAM) enzymes play a pivotal role. In the biosynthetic pathway of the antibiotic and anti-cancer agent thiostrepton A, TsrM, a B12/rSAM enzyme, catalyses the transfer of a methyl group to an electrophilic carbon atom of tryptophan. Here we show that methylcob(III)alamin is the probable physiological enzyme cofactor, and cob(II)alamin rather than cob(I)alamin is a key reaction intermediate. Furthermore, we establish that TsrM and a triple-alanine mutant alkylate cob(II)alamin efficiently leading to the synthesis of MeCbl. Exploiting TsrM substrate ambiguity, we demonstrate that TsrM does not catalyse substrate H-atom abstraction like most radical SAM enzymes. Based on these data, we propose an unprecedented radical-based C-methylation mechanism, which further
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
Allergy Research Group features B12 Adenosylcobalamin a highly absorbable form of vitamin B12. Vitamin B12 plays a role in brain and nervous system health. Also features folic...
Mihaela Testfamily: Neue Serie von Wellness & Beauty: Taufrisch belebt wird meins! #neubeirossmann #Rossmann #wellnessandbeauty #Lemongras #Beauty #Peeling #Spa
I am considering the addition of adenosylcobalamin to my supplements. Which brand do you use? I want one without folic acid/folate added. Thanks!
A 1973 study suggests that once absorbed, MeCbl may be retained in the body better than CNCbl (1).. A 2011 clinical trial from Korea found that 1,500 µg/day of MeCbl was effective at raising vitamin B12 levels, reducing or eliminating neurological symptoms of B12 deficiency, and lowering homocysteine levels (5). This trial was done on people who had a gastrectomy and, therefore, had vitamin B12 malabsorption, indicating that for most people 1,500 µg/day would be more than enough. There was no comparison group receiving CNCbl.. I am unaware of any clinical trials testing the various forms of vitamin B12 against each other among the general population and most people seem to do well using CNCbl.. Some people with chronic fatigue report getting more relief from AdoCbl than either MeCbl or CNCbl (more info), while other people report feeling better only when taking both AdoCbl and MeCbl. Its possible this could be a real effect, but could also be due to a placebo effect or taking more B12 and ...
Reactome is pathway database which provides intuitive bioinformatics tools for the visualisation, interpretation and analysis of pathway knowledge.

Clostridium sticklandii - WikipediaClostridium sticklandii - Wikipedia

Clostridium sticklandii shares the highest number of genes that are homologous with Clostridium difficile (a pathogenic species ... sticklandii. One such selenoprotein, glycine reductase A was first identified in Cl. sticklandii. C. sticklandii uses a total ... Clostridium sticklandii is an anaerobic, motile, gram-positive bacterium. It was first isolated in 1954 from the black mud of ... Clostridium sticklandii has a genome that consists of one circular chromosome. On this chromosome are 2,715,461 base pairs. Of ...
more infohttps://en.wikipedia.org/wiki/Clostridium_sticklandii

Frontiers | Evolution of plant δ1-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives | Plant...Frontiers | Evolution of plant δ1-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives | Plant...

Proline biosynthesis from L-ornithine in Clostridium sticklandii: purification of δ1-pyrroline-5-carboxylate reductase, and ...
more infohttps://www.frontiersin.org/articles/10.3389/fpls.2015.00567/full

dextro,laevo-alanine, 302-72-7dextro,laevo-alanine, 302-72-7

Fermentation of ornithine by Clostridium sticklandii.. PubMed: Taste stimuli: a behavioral categorization.. ...
more infohttp://www.thegoodscentscompany.com/data/rw1043861.html

2,4-diaminopentanoate dehydrogenase - Wikipedia2,4-diaminopentanoate dehydrogenase - Wikipedia

Tsuda Y, Friedmann HC (1970). "Ornithine metabolism by Clostridium sticklandii. Oxidation of ornithine to 2-amino-4- ... Stadtman TC (1973). "Lysine metabolism by clostridia. XIIB 2,4-Diaminohexanoate dehydrogenase (2,4-diaminopentanoate ...
more infohttps://en.wikipedia.org/wiki/2,4-diaminopentanoate_dehydrogenase

New Developments in the Field of Vitamin B12  Enzymatic Reactions Dependent upon Corrins
      and Coenzyme B12.New Developments in the Field of Vitamin B12 Enzymatic Reactions Dependent upon Corrins and Coenzyme B12.

Clostridium tetranomorpkum Ciostridium barkeri L-P-lysine aminomutase Clostridium sticklandii (I) (11) ca. 60000 [a] Km(Rbm), ... 60000 160000 Km(Rb"),MgZm(Mn2"). ATP, pyridoxal phosphate Ornithine aminomutase Clostridium sticklandii (I) ca. 60000 160000 ... by Clostridium ther51. The net reactions which occur are summarized rno~ceticum[~ in eqs. (e) to (g)[261. [email protected] 8 H + + 2 HzO 2 ... sticklandii catalyze the reversible conversion of a-lysine into P-lysine. Analogous isomerizations were observed with arginine ...
more infohttps://www.docme.ru/doc/1949027/new-developments-in-the-field-of-vitamin-b12--enzymatic-r..

EC 5.4.3.3EC 5.4.3.3

V. Some properties of the cobamide coenzyme-dependent β-lysine mutase of Clostridium sticklandii. Arch. Biochem. Biophys. 125 ( ... 6-aminomutase from Clostridium sticklandii. J. Biol. Chem. 275 (2000) 106-114. [PMID: 10617592]. 6. Tang, K.H., Harms, A. and ... properties of an adenosine triphosphate regulated B12-coenzyme-dependent D-α-lysine mutase complex from Clostridium sticklandii ...
more infohttps://www.qmul.ac.uk/sbcs/iubmb/enzyme/EC5/4/3/3.html

Microorganisms  | Free Full-Text | Feeding Essential Oils to Neonatal Holstein Dairy Calves Results in Increased Ruminal...Microorganisms | Free Full-Text | Feeding Essential Oils to Neonatal Holstein Dairy Calves Results in Increased Ruminal...

Clostridium sticklandii and Peptostreptococcus anaerobius were found to be the most sensitive species, while Streptococcous ...
more infohttps://www.mdpi.com/2076-2607/7/5/120/htm

Code System ConceptCode System Concept

Clostridium sticklandii (organism). Code System Preferred Concept Name. Clostridium sticklandii (organism). Concept Status. ...
more infohttps://phinvads.cdc.gov/vads/ViewCodeSystemConcept.action?oid=2.16.840.1.113883.6.96&code=78437006

JoVE | Peer Reviewed Scientific Video Journal - Methods and ProtocolsJoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols

Clostridium sticklandii belongs to a cluster of non-pathogenic proteolytic clostridia which utilize amino acids as carbon and ... Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence. ... It consists of at least three similar peptides active against Clostridium perfringens. In this article, a 15-kb region from R. ... With the goal of revisiting its carbon, nitrogen, and energy metabolism, and comparing studies with other clostridia, its ...
more infohttps://www.jove.com/visualize?author=Val%C3%A9rie+Barbe

Pre GI: BLASTP HitsPre GI: BLASTP Hits

Host Lineage: Clostridium sticklandii; Clostridium; unclassified Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria. ... Clostridium sticklandii is a Gram-positive bacterium with low (G +C) content that is capable of fermenting amino acids.. ... Query: NC_014614:1166009:1182842 Clostridium sticklandii, complete genome. Start: 1182842, End: 1183867, Length: 1026. ... General Information: This Clostridium (HF strain, ATCC 12662) was initially found associated with Methanococcus vannieli in ...
more infohttp://pregi.bi.up.ac.za/pre_gi_blast.php?blast_source_accession=NC_014614&blast_cds_query=NC_014614:1166009:1182842

Pre GI: BLASTP HitsPre GI: BLASTP Hits

Clostridium sticklandii, complete genome. bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II ...
more infohttp://pregi.bi.up.ac.za/pre_gi_blast.php?blast_source_accession=NC_009655&blast_cds_query=NC_009655:195500:209847

JoVE | Peer Reviewed Scientific Video Journal - Methods and ProtocolsJoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols

Kenland) phenolic compounds and their screening for activity against Clostridium sticklandii, a hyper ammonia-producing ...
more infohttps://www.jove.com/visualize/abstract/22164216/can-arbuscular-mycorrhizal-fungi-reduce-growth-agricultural

Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni | Parasites & Vectors | Full TextChemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni | Parasites & Vectors | Full Text

Clostridium sticklandii and C. valericum, gram-positive anaerobic bacteria belonging to the proteolytic clostridia, can produce ... Fermentation of delta-aminovaleric acid by Clostridium aminovalericum n. sp. J Bacteriol. 1960, 79: 549-552.PubMed Central ... Elsden SR, Hilton MG, Waller JM: The end products of the metabolism of aromatic amino acids by Clostridia. Arch Microbiol. 1976 ... Clostridium difficile and Lactobacillus strains are known to produce p-cresol by decarboxylation of p-hydroxyphenylacetate [32 ...
more infohttps://parasitesandvectors.biomedcentral.com/articles/10.1186/1756-3305-4-179

selenoprotein A - Semantic Scholarselenoprotein A - Semantic Scholar

A probe based on the sequence of the gene encoding selenoprotein A of glycine reductase of Clostridium sticklandii was used to ... The selenoprotein A component of the glycine reductase complex of Clostridium sticklandii was shown to differ in certain… (More ... The complete amino acid sequence of Clostridium sticklandii selenoprotein A, a selenocysteine-containing protein component of ... properties and biological activities of selenoprotein A components isolated from Clostridium sticklandii and Clostridium… ...
more infohttps://www.semanticscholar.org/topic/selenoprotein-A/282770

Protein‐Derived CofactorsProtein‐Derived Cofactors

1999) Identification of d‐proline reductase from Clostridium sticklandii as a selenoenzyme and indications for a catalytically ...
more infohttp://www.els.net/WileyCDA/ElsArticle/refId-a0000664.html

Amino acid fermentation at the origin of the genetic code | Biology Direct | Full TextAmino acid fermentation at the origin of the genetic code | Biology Direct | Full Text

Clostridium sticklandii, a specialist in amino acid degradation: revisiting its metabolism through its genome sequence. Bmc ... and heterocyclic-compounds participating in stickland reaction of clostridium-sticklandii. Arch Mikrobiol. 1973, 93 (3): 267- ... Stadtman TC: On the metabolism of an amino acid fermenting Clostridium. J Bacteriol. 1954, 67 (3): 314-320.PubMedPubMed Central ... If Clostridium would be the most ancient bacteria, so that this mode of energy metabolism is reserved here, but not in the ...
more infohttps://biologydirect.biomedcentral.com/articles/10.1186/1745-6150-7-6

The microbial selenoproteome of the Sargasso Sea | Genome Biology | Full TextThe microbial selenoproteome of the Sargasso Sea | Genome Biology | Full Text

Identification of D-proline reductase from Clostridium sticklandii as a selenoenzyme and indications for a catalytically active ...
more infohttps://genomebiology.biomedcentral.com/articles/10.1186/gb-2005-6-4-r37

Nitrogen and fatty acid rumen metabolism in cattle offered high or low polyphenol oxidase red clover silageNitrogen and fatty acid rumen metabolism in cattle offered high or low polyphenol oxidase red clover silage

... extracts assayed against Clostridium sticklandii, a ruminal hyper ammonia-producing bacterium. Natural Product Communications 7 ... Antimicrobial effect of red clover (Trifolium pratense) extract on the ruminal hyper-ammonia producing bacterium, Clostridium ... sticklandii . Current Microbiology 61, 125-131.. Gadeyne, F, De Neve, N, Vlaeminck, B, Claeys, E, Van der Meeren, P and Fievez ...
more infohttp://core-cms.prod.aop.cambridge.org/core/journals/animal/article/nitrogen-and-fatty-acid-rumen-metabolism-in-cattle-offered-high-or-low-polyphenol-oxidase-red-clover-silage/F2022FF779045F3C80B5CE6196BBD26E/core-reader

Red Clover (Trifolium pratense) - Organic Herbs, Herbal Tea, Handmaid Soap, Essential OilsRed Clover (Trifolium pratense) - Organic Herbs, Herbal Tea, Handmaid Soap, Essential Oils

... clostridium sticklandii. Current Microbiology, 61(2), 125-31. doi:http://dx.doi.org/10.1007/s00284-010-9586-5. NOTES AND MEDIA ...
more infohttps://www.bearberryessentials.com/holistic-blog/red-clover-trifolium-pratense

ASMscience | tRNAASMscience | tRNA

... amino acid selenocysteine in proteins was first demonstrated for protein A of glycine reductase from Clostridium sticklandii in ...
more infohttp://www.asmscience.org/content/book/10.1128/9781555818333

Diversity and Evolution in the Genome of Clostridium difficileDiversity and Evolution in the Genome of Clostridium difficile

Clostridium sticklandii, a specialist in amino acid degradation: revisiting its metabolism through its genome sequence. BMC ... Australia-home of Clostridium difficile clade 5?, abstr P53. Abstr 4th Int Clostridium difficile Symp, Bled, Slovenia. ... Clostridium difficile Infection. Clostridium difficile is a spore-forming, Gram-positive, anaerobic bacillus found ubiquitously ... In 2013, further taxonomic revision of the Clostridia was called for, with a proposed name change from Clostridium to ...
more infohttp://pubmedcentralcanada.ca/pmcc/articles/PMC4475645/

RCSB PDB - Protein Feature View 









 - L-lysine 2,3-aminomutase - Q9XBQ8 (KAMA CLOSU)RCSB PDB - Protein Feature View - L-lysine 2,3-aminomutase - Q9XBQ8 (KAMA CLOSU)

E3PRJ8 - Clostridium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654) no matching PDB entries ... Q9XBQ8 - Clostridium subterminale 1 * O34676 - Bacillus subtilis (strain 168) no matching PDB entries ...
more infohttp://www.rcsb.org/pdb/protein/Q9XBQ8

Amino acid utilization patterns in clostridial taxonomy.  - PubMed - NCBIAmino acid utilization patterns in clostridial taxonomy. - PubMed - NCBI

Clostridium botulinum type F (proteolytic), C. ghoni, C. mangenoti and C. putrificum were found to reduce proline to 5- ... C. botulinum type G and C. subterminale used glycine, lysine, serine, and arginine but in contrast to C. sticklandii they ... The method has been used to study the amino acids metabolized by cultures of proteolytic clostridia growing in a medium ... aminovaleric acid and to produce 2-aminobutyric acid, properties they shared with C. sporogenes and C. sticklandii. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/539867?dopt=Abstract