Clostridium sordellii
Clostridium
Clostridium difficile
Bacterial Toxins
Endometritis
Antitoxins
Spores
Neuromuscular Junction Diseases
Conditions characterized by impaired transmission of impulses at the NEUROMUSCULAR JUNCTION. This may result from disorders that affect receptor function, pre- or postsynaptic membrane function, or ACETYLCHOLINESTERASE activity. The majority of diseases in this category are associated with autoimmune, toxic, or inherited conditions.
Uridine Diphosphate Glucose
A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
Classification
Cytotoxins
Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
Clostridium botulinum
A species of anaerobic, gram-positive, rod-shaped bacteria in the family Clostridiaceae that produces proteins with characteristic neurotoxicity. It is the etiologic agent of BOTULISM in humans, wild fowl, HORSES; and CATTLE. Seven subtypes (sometimes called antigenic types, or strains) exist, each producing a different botulinum toxin (BOTULINUM TOXINS). The organism and its spores are widely distributed in nature.
Enterotoxins
Glucosyltransferases
rac GTP-Binding Proteins
Shock, Septic
A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity. (1/28)
Large clostridial toxins glucosylate some small G proteins on a threonine residue, thereby preventing their interactions with effector molecules and regulators. We show that the glucosyltransferase domain of lethal toxin from Clostridium sordellii (LT(cyt); amino acids 1-546), which is released into the cytosol during cell infection, binds preferentially to liposomes containing phosphatidylserine as compared with other anionic lipids. The binding of LT(cyt) to phosphatidylserine increases by two orders of magnitude the rate of glucosylation of liposome-bound geranyl-geranylated Rac-GDP. Limited proteolysis and deletion studies show that the binding site for phosphatidylserine lies within the first 18 N-terminal residues of LT(cyt). Deletion of these residues abolishes the effect of phosphatidylserine on the activity of LT(cyt) on liposome-bound geranyl-geranylated Rac-GDP and prevents the morphological effects induced by LT(cyt) microinjection into various cells, but it does not affect the intrinsic activity of LT(cyt) on non-geranyl-geranylated Rac-GDP in solution. We conclude that the avidity of LT(cyt) for phosphatidylserine facilitates its targeting to the cytosolic leaflet of cell membranes and, notably, the plasma membrane, where this anionic lipid is abundant and where several targets of lethal toxin reside. (+info)Clostridium sordellii toxic shock syndrome after medical abortion with mifepristone and intravaginal misoprostol--United States and Canada, 2001-2005. (2/28)
On July 19, 2005, the Food and Drug Administration (FDA) issued a public health advisory regarding the deaths of four women in the United States after medical abortions with Mifeprex (mifepristone, formerly RU-486; Danco Laboratories, New York, New York) and intravaginal misoprostol. Two of these deaths occurred in 2003, one in 2004, and one in 2005. Two of these U.S. cases had clinical illness consistent with toxic shock and had evidence of endometrial infection with Clostridium sordellii, a gram-positive, toxin-forming anaerobic bacteria. In addition, a fatal case of C. sordellii toxic shock syndrome after medical abortion with mifepristone and misoprostol was reported in 2001, in Canada. All three cases of C. sordellii infection were notable for lack of fever, and all had refractory hypotension, multiple effusions, hemoconcentration, and a profound leukocytosis. C. sordellii previously has been described as a cause of pregnancy-associated toxic shock syndrome. (+info)Fatal toxic shock syndrome associated with Clostridium sordellii after medical abortion. (3/28)
Endometritis and toxic shock syndrome associated with Clostridium sordellii have previously been reported after childbirth and, in one case, after medical abortion. We describe four deaths due to endometritis and toxic shock syndrome associated with C. sordellii that occurred within one week after medically induced abortions. Clinical findings included tachycardia, hypotension, edema, hemoconcentration, profound leukocytosis, and absence of fever. These cases indicate the need for physician awareness of this syndrome and for further study of its association with medical abortion. (+info)Sudden death associated with Clostridium sordellii in captive lions (Panthera leo). (4/28)
In the spring of 2003, a series of sudden deaths in a group of adult lions (Panthera leo) with a previous history of depression, inanition, and lethargy, was investigated. Five animals died within 24 to 36 hours after onset of signs of disease. Serologic screening for viral disease detection was negative, evidence of parasites was not detected, and results of a complete blood count and serum biochemical analysis were within reference intervals in all lions. The most relevant lesions observed were multiple areas of necrosis and hemorrhage in the intestinal outer muscular layer, and cellulitis with an intense bloody edema in the mesenteric and the pericardial fat tissue. On the basis of the fulminant course of the disease, the gross and histologic findings, and the isolation and identification of Clostridium sordellii, a diagnosis of infectious myositis and cellulitis associated with acute clostridiosis was made. To the authors' knowledge, this is the first report of sudden death associated with C. sordellii in felines. (+info)Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment. (5/28)
Clostridium sordellii infections pose difficult clinical challenges and are usually fatal. Most commonly, these infections occur after trauma, childbirth, and routine gynecological procedures, but they have recently been associated with medically induced abortions and injection drug use. We report 2 fatal cases, one of which was associated with minor trauma, and the other of which was associated with normal childbirth, and we summarize the clinical features of 43 additional cases of reported C. sordellii infection. Of these 45 cases, 8 (18%) were associated with normal childbirth, 5 (11%) were associated with medically induced abortion, and 2 (0.4%) were associated with spontaneous abortion. The case-fatality rate was 100% in these groups. Ten (22%) of the C. sordellii infections occurred in injection drug users, and 50% of these patients died. Other cases of C. sordellii infection (in 19 patients [43%]) occurred after trauma or surgery, mostly in healthy persons, and 53% these patients died. Overall, the mortality rate was 69% (31 of 45 patients). Eighty-five percent of all patients with fatal cases died within 2-6 days of initial infection, and nearly 80% of fatal cases developed leukemoid reactions. Rapid diagnostic tests and improved treatments are needed to reduced the morbidity and mortality associated with this devastating infection. (+info)Infection of internal umbilical remnant in foals by Clostridium sordellii. (6/28)
Omphalitis and the resulting septicemia contribute to perinatal mortality in several animal species. In foals, the most important causes of omphalitis are Escherichia coli and Streptococcus zooepidemicus. However to date, no information has been published about the role of Clostridium sordellii in these infections. In this paper, we describe 8 cases of perinatal mortality in foals associated with internal umbilical remnant infection by C. sordellii. The foals studied were between 12 and 21 days old at the time of death, and various breeds were represented in the group. Five of the foals were male and 3 were female. The diagnosis was established on the basis of the detection of C. sordellii by 3 methods (culture, fluorescent antibody test, and immunohistochemistry) and on gross and histopathologic findings. All foals had acute peritonitis, and the internal umbilical remnant was thickened by edema, hemorrhage, and fibrosis. A moderate amount of serosanguinous fluid with fibrin strands was present in the pericardial sac and pleural cavity. Histopathologically, the urachus and umbilical arterial walls were thickened by edema and exhibited hemorrhage, fibrin, and leukocytic infiltration. Gram-positive bacterial rods were observed in subepithelial areas of the urachus, the adventicia of umbilical arteries, and interstitium of the internal umbilical remnant. On the basis of these findings, we suggest that C. sordellii should be considered in the differential diagnosis for infections of the internal umbilical remnant in foals. (+info)The leukemoid reaction in Clostridium sordellii infection: neuraminidase induction of promyelocytic cell proliferation. (7/28)
Life-threatening Clostridium sordellii infections have recently been reported in women undergoing therapeutic abortion, during natural childbirth, and in injection drug users. Shock, diffuse capillary leak, and a leukemoid reaction (LR) are cardinal features of these infections. The magnitude of the LR is highly correlated with mortality. We have isolated a 42-kDa extractable protein from C. sordellii culture supernatant that stimulates proliferation of promyelocytic HL-60 cells in vitro. Using mass spectrometry, we have identified this protein as the C. sordellii neuraminidase, NanS. Recombinant NanS (rNanS) dose dependently stimulated HL-60 cell proliferation. Increased proliferation was observed when HL-60 cells were cocultured with both rNanS and granulocyte-macrophage colony stimulating factor. In addition, NanS also modified vascular cell adhesion molecule 1, which orchestrates the release of mature and immature granulocytes from bone marrow stromal cells. Thus, neuraminidase likely plays an important role in the characteristic LR in C. sordellii infection. (+info)The large clostridial toxins from Clostridium sordellii and C. difficile repress glucocorticoid receptor activity. (8/28)
We have previously shown that Bacillus anthracis lethal toxin represses glucocorticoid receptor (GR) transactivation. We now report that repression of GR activity also occurs with the large clostridial toxins produced by Clostridium sordellii and C. difficile. This was demonstrated using a transient transfection assay system for GR transactivation. We also report that C. sordellii lethal toxin inhibited GR function in an ex vivo assay, where toxin reduced the dexamethasone suppression of the proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha). Furthermore, the glucocorticoid antagonist RU-486 in combination with C. sordellii lethal toxin additively prevented glucocorticoid suppression of TNF-alpha. These findings corroborate the fact that GR is a target for the toxin and suggest a physiological role for toxin-associated GR repression in inflammation. Finally, we show that this repression is associated with toxins that inactivate p38 mitogen-activated protein kinase (MAPK). (+info)
Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment
How do you know if you have a post-abortion infection? @ Women on Waves
Comparative genomic and phenomic analysis of Clostridium difficile and Clostridium sordellii , two related pathogens with...
Toxins | Free Full-Text | Role of p38alpha/beta MAP Kinase in Cell Susceptibility to Clostridium sordellii Lethal Toxin and...
Clostridium sordellii (Hall and Scott) Prevot ATCC ® 9714™
Clostridium sordellii (Hall and Scott) Prevot ATCC ® 9714™
Prophylactic antibiotics for medical abortion
Clostridial toxin financial definition of clostridial toxin
Notice to Readers: Unexplained Deaths Following Knee Surgery ---
Minnesota, November 2001
Mifepriston - Wikipedia, wolna encyklopedia
Effect of filtrate containing Clostridium difficile toxin on rectal mucosa maintained in organ culture. - Experimental Medicine...
Microbiology Society Journals | Assessing the role of p-cresol tolerance in Clostridium difficile
Patent US8017131 - Clostridial toxin derivatives and methods for treating pain - Google Patents
Patent US6623742 - Methods for treating fibromyalgia - Google Patents
Extreme leukocytosis and leukemoid reaction associated with the lung s | IJGM
Direct link
KoreaMed Synapse
Leukemoid reaction in pulmonary carcinoma.
Conference 15 - 2012 Case: 02 20130220
North Country Mercantile
MBBS Medicine (Humanity First): What is LR?
IJMS | Free Full-Text | Decidual Macrophages Are Significantly Increased in Spontaneous Miscarriages and Over-Express FasL: A...
One Shot Ultra 8 Cattle Vaccine | Jeffers Pet
Flow cytometric characterisation of cell populations in human pregnancy decidua and isolation of decidual macrophages. -...
Bay City Feed | Vision 8 Cattle & Sheep Disease Control - Bay City, TX
Supplementary Materialsijms-20-05994-s001 | Novel EGFR inhibitors attenuate cardiac hypertrophy
This model lost her leg to Toxic Shock Syndrome. What is it? - Rediff.com Get Ahead
Severe leukocytosis with neutrophilia (leukemoid reaction) in alcoholic steatohepatitis. - PubMed - NCBI
DMOZ - Health: Conditions and Diseases: Infectious Diseases: Bacterial: Staphylococcal: Toxic Shock Syndrome
A48.3 TOXIC SHOCK SYNDROME
Health Tip: Avoiding Toxic Shock Syndrome - Drugs.com MedNews
Parents warned about danger of Toxic Shock Syndrome (TSS) | MadeForMums
Structure of most lethal toxin produced by C. difficile bacteria identified
Clostridial vaccine
Clostridium haemolyticum Clostridium novyi Clostridium perfringens Clostridium septicum Clostridium sordellii Clostridium ... Clostridial vaccines can contain anti-toxins to one or more endotoxins produced by the following bacteria: Clostridium chauvoei ... for sheep and cattle that protects against diseases caused by toxins produced by an infection with one or more Clostridium ...
Clostridium novyi
Just I, Selzer J, Hofmann F, Green GA, Aktories K (April 1996). "Inactivation of Ras by Clostridium sordellii lethal toxin- ... toxins of Clostridium difficile show homology with the alpha-toxin of C novyi as does the lethal toxin of clostridium sordellii ... Clostridium novyi (oedematiens) a Gram-positive, endospore- forming, obligate anaerobic bacteria of the class Clostridia. It is ... Gas gangrene: infectious necrotic hepatitis (black disease) Clostridium novyi-NT, an attenuated form of Clostridium novyi-NT ...
Clostridial Cytotoxin family
pH-dependent channel formation has been demonstrated for C. difficile Toxin B and C as well as Clostridium sordellii lethal ... Clostridium difficile toxin B Clostridium difficile colitis Clostridium difficile (bacteria) RTX toxin Transporter ... Pruitt RN, Chambers MG, Ng KK, Ohi MD, Lacy DB (July 2010). "Structural organization of the functional domains of Clostridium ... Clostridium difficile, the causative agent of nosocomial antibiotic-associated diarrhea and pseudomembranous colitis, possesses ...
Poultry farming
GD is caused by Clostridium septicum, Clostridium perfringens type A, Clostridium sordellii, Clostridium novyi, Staphylococcus ...
Abomasitis
Schamber, G.J.; Berg, I.E.; Molesworth, J.R. (April 1986). "Braxy or Bradsot-like Abomastitis Caused by Clostridium septicum in ... sordellii, and Sarcina spp.) Viruses like Rinderpest morbillivirus or Pestivirus can also cause an inflammation of the mucosa, ... Abomasitis can be caused by several factors: Bacterial infections (e.g. Clostridium septicum, C. perfringens (type A), C. ...
Necrotizing fasciitis
Clostridium species involved are Clostridium perfringens, Clostridium septicum, and Clostridium sordellii, which typically ... Clostridium sordellii can also produce two major toxins: all known virulent strains produce the essential virulence factor ... The key Clostridium septicum virulence factor is a pore-forming toxin called alpha-toxin, though it is unrelated to the ... Bacteroides and Clostridium species). Populations of those affected are typically older with medical comorbidities such as ...
List of Clostridium species
Genus Oxobacter: Clostridium pfennigii, reassigned in 1994. Genus Paeniclostridium: Clostridium ghonii and C. sordellii, ... Clostridium aceticum Clostridium acetireducens Clostridium acetobutylicum Clostridium acidisoli Clostridium aciditolerans ... Clostridium aestuarii Clostridium akagii Clostridium algidicarnis Clostridium algifaecis Clostridium algoriphilum Clostridium ... Clostridium novyi Clostridium oceanicum Clostridium oryzae Clostridium paradoxum Clostridium paraputrificum Clostridium pascui ...
Clostridium difficile toxin B
These bacterial toxins have been shown to be associated with Clostridium sordellii hemorrhagic toxin (TcsH), lethal toxin (TcsL ... Clostridium difficile toxin B is a cytotoxin produced by the bacteria Clostridioides difficile, formerly known as Clostridium ... Clostridium difficile TcdE Holin Holin Reinert DJ, Jank T, Aktories K, Schulz GE (September 2005). "Structural basis for the ... With regard to Clostridium difficile-associated diarrhea (CDAD), the effects of cytopathicity are more critical than actual ...
Paeniclostridium sordellii
McGregor.pdf Pathema-Clostridium Resource Type strain of Clostridium sordellii at BacDive - the Bacterial Diversity ... M. J. Aldape, A. E. Bryant, D. L. Stevens; Clostridium sordellii Infection: Epidemiology, Clinical Findings, and Current ... C. sordellii bacteremia and sepsis occur rarely. Most cases of sepsis from C. sordellii occur in patients with underlying ... Pathophysiology of mifepristone-induced septic shock due to Clostridium sordellii. Ann Pharmacother 2005; 39:1483-8 Nakamura S ...
Clostridium
... difficile, now placed in Clostridioides. Clostridium histolyticum, now placed in Hathewaya. Clostridium sordellii, ... Mixtures of Clostridium species, such as Clostridium beijerinckii, Clostridium butyricum, and species from other genera have ... Clostridium welchii and Clostridium tetani respond to sulfonamides. Clostridia are also susceptible to tetracyclines, ... Meites E, Zane S, Gould C (September 2010). "Fatal Clostridium sordellii infections after medical abortions". The New England ...
List of MeSH codes (B03)
Clostridium perfringens MeSH B03.300.390.400.200.700 - Clostridium sordellii MeSH B03.300.390.400.200.710 - Clostridium ... Clostridium perfringens MeSH B03.510.415.400.200.700 - Clostridium sordellii MeSH B03.510.415.400.200.710 - Clostridium ... Clostridium botulinum type G MeSH B03.300.390.400.200.180 - Clostridium butyricum MeSH B03.300.390.400.200.200 - Clostridium ... Clostridium botulinum type G MeSH B03.510.415.400.200.180 - Clostridium butyricum MeSH B03.510.415.400.200.200 - Clostridium ...
Clostridium sordellii
| HAI | CDC
General Information about C. sordellii. Clostridium sordellii [klaw-strĭ-dee-um sore-dell-ee-i] (also called C. sordellii) is a ... Toxic shock associated with clostridium sordellii and clostridium perfringens after medical and spontaneous abortion.external ... It is not known how C. sordellii is spread between persons or from the environment to persons. Other similar Clostridium ... For more information see the Clostridium sordellii Toxic Shock Syndrome After Medical Abortion with Mifepristone and ...
Bacterial Infections: March 2006
Gas Gangrene (Clostridial Myonecrosis) Treatment & Management: Medical Care, Surgical Care, Consultations
In 1861, Louis Pasteur identified the first clostridial species, Clostridium butyricum. ... clostridial myonecrosis are interchangeable terms used to describe an infection of muscle tissue by toxin-producing clostridia ... Fatal toxic shock syndrome associated with Clostridium sordellii after medical abortion. N Engl J Med. 2005 Dec 1. 353(22):2352 ... Clostridium perfringens gas gangrene at a wrist intravenous line insertion. BMJ Case Rep. 2013 Oct 9. 2013:[QxMD MEDLINE Link] ...
Gas Gangrene (Clostridial Myonecrosis) Workup: Laboratory Studies, Imaging Studies, Other Tests
In 1861, Louis Pasteur identified the first clostridial species, Clostridium butyricum. ... clostridial myonecrosis are interchangeable terms used to describe an infection of muscle tissue by toxin-producing clostridia ... Fatal toxic shock syndrome associated with Clostridium sordellii after medical abortion. N Engl J Med. 2005 Dec 1. 353(22):2352 ... Clostridium perfringens gas gangrene at a wrist intravenous line insertion. BMJ Case Rep. 2013 Oct 9. 2013:[QxMD MEDLINE Link] ...
UltraChoice 8 for Animal Use - Drugs.com
Clostridium Chauvoei-Septicum-Haemolyticum-Novyi-Sordellii-Perfringens Types C & D Bacterin-Toxoid ... sordellii, and Cl. perfringens types C and D. Duration of immunity has not been established. For more information regarding ... product has been shown to be effective for the vaccination of healthy cattle and sheep against disease caused by Clostridium ...
Preliminary evidence for dormant clostridial spores in equine skeletal muscle - PubMed
Clostridium sordellii isolated from foals. Hibbs CM, Johnson DR, Reynolds K, Harrington R Jr. Hibbs CM, et al. Vet Med Small ... Clostridium sordellii-associated gas gangrene in 8 horses, 1998-2019. Sacco SC, Ortega J, Navarro MA, Fresneda KC, Anderson M, ... Clostridium novyi type A intra-abdominal abscess in a horse. Aleman M, Watson JL, Jang SS. Aleman M, et al. J Vet Intern Med. ... Acute myonecrosis in horse caused by Clostridium novyi type A. Farias LD, Azevedo Mda S, Trost ME, De La Côrte FD, Irigoyen LF ...
Table of contents | Journal of Clinical Pathology
These highlights do not include all the information needed to use Mifepristone tablets, 200mg safely and effectively. See full...
A high index of suspicion is needed to rule out sepsis (e.g., from Clostridium sordellii) if a patient reports abdominal pain ... Clostridium sordellii infections have also been reported very rarely following childbirth (vaginal delivery and caesarian ... Patients with serious bacterial infections (e.g., Clostridium sordellii) and sepsis can present without fever, bacteremia, or ...
Toxins | March 2016 - Browse Articles
This article belongs to the Collection Clostridium difficile/Clostridium sordellii and Clostridium perfringens Toxins). ... This article belongs to the Collection Clostridium difficile/Clostridium sordellii and Clostridium perfringens Toxins). ... Clostridium perfringens enterotoxin (CPE) is responsible for causing the gastrointestinal symptoms of several C. perfringens ... Clostridium perfringens enterotoxin (CPE) is responsible for causing the gastrointestinal symptoms of several C. perfringens ...
Health Professional FAQs
Patients with serious bacterial infections (e.g., Clostridium sordellii) and sepsis can present without fever, bacteremia or ... Patients with serious bacterial infections (e.g., Clostridium sordellii) and sepsis can present without fever, bacteremia or ... Patients with serious bacterial infections (e.g., Clostridium sordellii) and sepsis can present without fever, bacteremia or ...
Elective Abortion: Background, Pathophysiology, Epidemiology
Depot-medroxyprogesterone acetate: an update - PubMed
Hygromycin B, Streptomyces sp. - CAS 31282-04-9 - Calbiochem Unique aminoglycoside antibiotic that inhibits the growth of...
The exotoxin TcsL is a major virulence factor in Paeniclostridium (Clostridium) sordellii and responsible for the high ... Genome-Wide CRISPR Screen Identifies Semaphorin 6A and 6B as Receptors for Paeniclostridium sordellii Toxin TcsL. ... lethality rate associated with P. sordellii infection. Here, we present a genome-wide CRISPR-Cas9-mediated screen using a human ...
Plan B: Abortifacient and Other Risks - Charlotte Lozier Institute
TREE NUMBER DESCRIPTOR
Clostridium perfringens B03.300.390.400.200.690 Clostridium septicum B03.300.390.400.200.700 Clostridium sordellii B03.300. ... Clostridium perfringens B03.353.625.375.500.690 Clostridium septicum B03.353.625.375.500.700 Clostridium sordellii B03.353. ... Clostridium perfringens B03.510.415.400.200.690 Clostridium septicum B03.510.415.400.200.700 Clostridium sordellii B03.510. ... Clostridium botulinum type A B03.300.390.400.200.160.100 Clostridium botulinum type B B03.300.390.400.200.160.150 Clostridium ...
Bloodstream and endovascular infections due to Abiotrophia defectiva and Granulicatellaspecies | BMC Infectious Diseases | Full...
NIH Research Festival 2005
Putative Conjugative Plasmids with tcdB and cdtAB Genes in Clostridioides difficile - Volume 26, Number 9-September 2020 -...
... and expected to encode variant TcdBs that would cause a Clostridium sordellii-like cytopathic effect. Besides its plasmid-borne ... Ramírez-Vargas G, López-Ureña D, Badilla A, Orozco-Aguilar J, Murillo T, Rojas P, et al. Novel Clade C-I Clostridium difficile ... Monot M, Eckert C, Lemire A, Hamiot A, Dubois T, Tessier C, et al. Clostridium difficile: new insights into the evolution of ... Balsells E, Shi T, Leese C, Lyell I, Burrows J, Wiuff C, et al. Global burden of Clostridium difficile infections: a systematic ...
Buy online Levitra Oral Jelly - Trusted Levitra Oral Jelly online no RX
MeSH Browser
Clostridium sordellii Preferred Term Term UI T571623. Date02/05/2004. LexicalTag NON. ThesaurusID NLM (2005). ... Clostridium [B03.300.390.400.200] * Clostridium acetobutylicum [B03.300.390.400.200.025] * Clostridium beijerinckii [B03.300. ... Clostridium [B03.353.625.375.500] * Clostridium acetobutylicum [B03.353.625.375.500.025] * Clostridium beijerinckii [B03.353. ... Clostridium [B03.510.415.400.200] * Clostridium acetobutylicum [B03.510.415.400.200.025] * Clostridium beijerinckii [B03.510. ...
Biomarkers Search
Haemorrhagic toxin and lethal toxin from Clostridium sordellii strain vpi9048: molecular characterization and comparative ... 8. Clostridium difficile toxin A-induced apoptosis is p53-independent but depends on glucosylation of Rho GTPases.. Nottrott S ... The Role of Rho GTPases in Toxicity of Clostridium difficile Toxins.. Chen S; Sun C; Wang H; Wang J. Toxins (Basel); 2015 Dec; ... 6. [Apoptosis-inducing effect of clostridium difficile toxin A on K562 cells and its mechanism].. Li P; Chen C; Xi YM; Zhang H ...
Ultrabac-7/Somubac - 200 ds Vial | VetDepot.com
ULTRACHOICE® 7 | Zoetis US
Types C and D Bacterin-Toxoid.For use in healthy cattle and sheep as an aid in preventing blackleg caused by Clostridium ... Clostridium Chauvoei-Septicum-Novyi-Sordellii-Perfringens Types C and D Bacterin-Toxoid. ... sordellii; and enterotoxemia and enteritis caused by Cl. perfringens Types B, C and D. Although Cl. perfringens Type B is not a ... Clostridium bacteria are universally present and produce potent toxins that can result in rapid death of otherwise healthy ...
MeSH Browser
Clostridium sordellii Preferred Term Term UI T571623. Date02/05/2004. LexicalTag NON. ThesaurusID NLM (2005). ... Clostridium [B03.300.390.400.200] * Clostridium acetobutylicum [B03.300.390.400.200.025] * Clostridium beijerinckii [B03.300. ... Clostridium [B03.353.625.375.500] * Clostridium acetobutylicum [B03.353.625.375.500.025] * Clostridium beijerinckii [B03.353. ... Clostridium [B03.510.415.400.200] * Clostridium acetobutylicum [B03.510.415.400.200.025] * Clostridium beijerinckii [B03.510. ...
Code System Concept
Find Research outputs - Keio University
Infection Control Assessment Tools | HAI | CDC
Chauvoei8
- For prevention of Clostridium chauvoei, septicum, novyi, sordellii and perfringens Types C & D. Give cattle and sheep 2 ml SQ. Repeat in 3 to 4 weeks and once annually. (valleyvet.com)
- Shown to be effective for the vaccination of healthy cattle against disease caused by Clostridium chauvoei (Blackleg), Cl. (merck-animal-health-usa.com)
- Cavalry 9 is for the vaccination of healthy cattle 3 months of age or older as an aid in the prevention of disease caused by Clostridium tetani, C. chauvoei, C. septicum, C. novyi Type B, C. haemolyticum, C. sordellii, and C. perfringens Types C & D. (wpvs.net)
- Vision 7 Somnus with SPUR aids in preventing disease caused by Clostridium chauvoei (Blackleg), septicum (Malignant edema), novyi (Black disease), sordellii, perfringens Types C & D (Enterotoxemia) and Haemophilus somnus in cattle. (wpvs.net)
- Additional clostridia implicated in wound infections include C chauvoei , C perfringens type A, C novyi type A, and C sordellii . (msdvetmanual.com)
- One Shot Ultra® 7 is effective for vaccination of healthy cattle against disease caused by Clostridium chauvoei, Cl. (centraloregonranchsupply.com)
- Ultrabac 8 is used in healthy cattle and sheep as an aid in preventing blackleg caused by Clostridium chauvoei, malignant edema caused by Cl septicum, bacillary hemoglobinuria caused by Cl. (hubersanimalhealth.com)
- They receive Bovine Rhinotracheitis- virus diarrhea- parainfluenza 3- respiratory syncytial virus vaccine, pulmo guard PHM-1 50Ds, cholostridium chauvoei- specticum- novyi- sordellii perfingens types C and D- haemophilus somnus bactrin-toxoid (Bar-Vac 7/ Somnus) before leaving for their forever homes. (pandarosaminiatureranch.com)
Paeniclostridium7
- The present study aimed to investigate the frequency, and the presence of virulence genes, of Clostridium perfringens, Paeniclostridium sordellii and Clostridium septicum in lambs and goat kids with hemorrhagic abomasitis. (bvsalud.org)
- Human infections caused by the toxin-producing, anaerobic and spore-forming bacterium Paeniclostridium sordellii are associated with a treatment-refractory toxic shock syndrome (TSS). (bvsalud.org)
- Hemorrhagic toxin (TcsH) is an important exotoxin produced by Paeniclostridium sordellii, but the exact role of TcsH in the pathogenesis remains unclear, partly due to the lack of knowledge of host receptor(s). (bvsalud.org)
- Paeniclostridium sordellii 211 is an anaerobe, mesophilic human pathogen of the family Clostridiaceae. (dsmz.de)
- Paeniclostridium sordellii (Hall and Scott 1927) Sasi Jyothsna et al. (dsmz.de)
- The comparative pathology of enterocolitis caused by Clostridium perfringens type C, Clostridioides difficile, Paeniclostridium sordellii, Salmonella enterica subspecies enterica serovar Typhimurium, and nonsteroidal anti-inflammatory drugs in horses. (academic-accelerator.com)
- However, the names have been changed for the two latter, which are now called Clostridioides difficile and Paeniclostridium sordellii , respectively. (vetbact.org)
Septicum3
- P. sordellii, C. perfringens type F and C. septicum were also harboured in the samples, albeit at low rates. (bvsalud.org)
- Clostridium septicum, the cause of malignant edema, is found in soil and intestinal contents of all species of animals. (msdvetmanual.com)
- Malignant edema is an acute, generally fatal toxemia affecting all species and ages of animals and is usually caused by Clostridium septicum . (msdvetmanual.com)
Bacteria9
- The rate of vaginal colonization (when bacteria are present, but not causing an infection) with Clostridium species in the period after abortion has been reported to be as high as 29%, whereas these bacteria have been isolated in the vaginal secretions of 5%-10% of non-pregnant women. (cdc.gov)
- Lastly, TSS is rarely caused by other toxin producing bacteria such as the anaerobic gram positive bacillus Clostridium sordellii(CS). (renalandurologynews.com)
- Last year federal health officials tied the four California deaths to sepsis, a serious blood infection caused by a bacteria known as Clostridium sordellii. (splendoroftruth.com)
- Clostridium includes common free-living bacteria as well as important pathogens. (splendoroftruth.com)
- Especie de bacteria grampositiva de la familia Clostridiaceae, que se encuentra en INTESTINOS y SUELO. (bvsalud.org)
- In Caprine this disease is caused by a bacteria called Clostridium perfringens type D, which is a gram positive, spore forming, anaerobic, and rod shaped. (academic-accelerator.com)
- Especie tipo del género CLOSTRIDIUM, bacteria grampositiva de la familia Clostridiaceae. (bvsalud.org)
- Type species of the genus CLOSTRIDIUM , a gram-positive bacteria in the family Clostridiaceae. (bvsalud.org)
- Clostridium bacteria are universally present and produce potent toxins that can result in rapid death of otherwise healthy animals. (centraloregonranchsupply.com)
Botulinum2
- 005.0 Staphylococcal food poisoning Staphylococcal toxaemia specified as due to food 005.1 Botulism Food poisoning due to Clostridium botulinum 005.2 Food poisoning due to Clostridium perfringens [Cl. (cdc.gov)
- Clostridium botulinum A2 str. (effectors.org)
Difficile2
- C. piliforme is like C. difficile and C. sordellii only distantly related to other clostridia as shown in the phylogenetic tree (see Fig. 28:1). (vetbact.org)
- Negative stool tests for C.difficile do not rule out the presence of other Clostridia species. (fourie.net.za)
Species5
- Other similar Clostridium species are spread from person to person and sometimes contaminated surfaces are involved in this transmission. (cdc.gov)
- Clostridium species are often associated with the female reproductive tract as non-virulent colonizers of the vagina. (renalandurologynews.com)
- Several Clostridium species have been associated with abomasitis in ruminants. (bvsalud.org)
- The examination of swab samples by culture and PCR revealed that C. perfringens type A was the most frequently detected species (86.84%) either alone or in combination with other Clostridium species. (bvsalud.org)
- About 175 different species have been described within the genus Clostridium . (vetbact.org)
Perfringens type5
- Clostridium perfringens type F strains cause the second most common bacterial foodborne illness in the United States. (academic-accelerator.com)
- Clostridium perfringens type A is a Gram-positive bacterium that causes gas gangrene characterized by severe myonecrosis. (academic-accelerator.com)
- 염소자리에서 이 질병은 Clostridium perfringens type D라고 하는 박테리아에 의해 유발되며, 이는 그람 양성, 포자 형성, 혐기성 및 막대 모양입니다. (academic-accelerator.com)
- ABSTRACT Clostridium perfringens type G strains cause necrotic enteritis (NE) in poultry, an economically important disease that is a major target of in-feed antibiotics. (academic-accelerator.com)
- Pandarosa babies receive clostridium perfringens Type C Antitoxin- Escherichia Coli Antibody, Bovine Rotavirus- Coronavirus Vaccine at birth. (pandarosaminiatureranch.com)
Bacillus1
- welchii] Enteritis necroticans 005.3 Food poisoning due to other Clostridia 005.4 Food poisoning due to Vibrio parahaemolyticus 005.8 Other bacterial food poisoning Food poisoning due to Bacillus cereus Excludes: salmonella food poisoning (003. (cdc.gov)
Clostridial1
- The most common clostridial infection is gastroenteritis ( Clostridium perfringens food poisoning), a usually mild infection that typically resolves on its own. (fourie.net.za)
Infection7
- Severe toxic shock syndrome among previously healthy persons has been described in a small number of C. sordellii cases, most often associated with gynecologic infections in women and infection of the umbilical stump in newborns. (cdc.gov)
- Women are at highest risk of infection from C. sordellii following the end of pregnancy, whether that pregnancy ended in a live birth, induced abortion (medical or surgical), or spontaneous abortion (miscarriage). (cdc.gov)
- Symptoms of a C. sordellii infection include nausea, vomiting, diarrhea, and sometimes abdominal pain without fever. (cdc.gov)
- Reproductive-age women are at increased risk for P. sordellii infection (PSI) because this organism can cause intrauterine infection following childbirth, stillbirth, or abortion. (bvsalud.org)
- By synchronizing the mice in diestrus with progesterone prior to transcervical inoculation with TcsL or vegetative P. sordellii, we observed highly reproducible intoxication and infection dynamics. (bvsalud.org)
- Furthermore, PA41 could provide protection following P. sordellii bacterial and spore infections, suggesting a path for further optimization and clinical translation in the effort to advance treatment options for PSI infection. (bvsalud.org)
- If makers 4-Hydroxyphenylacetic, HPHPA and 4-Cresol is elevated then you have a Clostridia infection. (fourie.net.za)
Enterotoxemia1
- sordellii, and enterotoxemia and enteritis caused by Cl. (hubersanimalhealth.com)
Acetobutylicum3
- Clostridium acetobutylicum" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
- This graph shows the total number of publications written about "Clostridium acetobutylicum" by people in Harvard Catalyst Profiles by year, and whether "Clostridium acetobutylicum" was a major or minor topic of these publication. (harvard.edu)
- Below are the most recent publications written about "Clostridium acetobutylicum" by people in Profiles. (harvard.edu)
Infections2
- Fatal infections with C. sordellii and C. perfringens have occurred after medical abortion. (cdc.gov)
- BACKGROUND: The pathogenic Clostridia cause neurotoxic, histotoxic and enterotoxic infections in humans and animals. (bvsalud.org)
20221
- 14:48, 15 March 2022 diff hist +582 N General Microbiology by Students of Jennifer Bhatnagar, Boston University Created page with 'Alphacoronavirus 1 Aspergillus tubingensis Bifidobacterium bifidum Clostridium limosum Dickeya solani E. cuniculi Eastern equine encephalitis virus Feline calicivirus Gambierd. (kenyon.edu)
Bacterium1
- Clostridium sordellii [klaw-strĭ-dee-um sore-dell-ee-i] (also called C. sordellii ) is a rare bacterium that causes pneumonia, endocarditis, arthritis, peritonitis, and myonecrosis. (cdc.gov)
Medical Abortion2
- For more information see the Clostridium sordellii Toxic Shock Syndrome After Medical Abortion with Mifepristone and Intravaginal Misoprostol - United States and Canada, 2001-2005 . (cdc.gov)
- 2004) A Fatal Case of Clostridium sordellii Septic Shock Syndrome Associated With Medical Abortion. (womenonwaves.org)
Strains1
- The 3 clade C-I strains were different, as confirmed by pairwise estimates of genomic MinHash (min-wise independent permutations locality sensitive hashing scheme) distances (0.022-0.049) calculated with MASH ( https://mash.readthedocs.io/en/latest/index.html ) and average nucleotide identities (94.15%-97.45%) calculated with FastANI ( https://github.com/ParBLiSS/FastANI ). (cdc.gov)
Toxins1
- The toxins released by Clostridia metabolites can inhibit key neurotransmitters in the brain. (fourie.net.za)
Toxic2
Cases2
- Most cases of sepsis from C. sordellii occur in patients with underlying conditions. (cdc.gov)
- In many cases, Clostridia overgrowth can be controlled by supplementation with 30 billion cells per day of Lactobacillus rhamnosus GG (Culturelle) and/or 2-6 billion cfu's of Saccharomyces boulardii. (fourie.net.za)
Common1
- Clostridium perfringens ( Gas Gangrene , also most common cause of acute Food Poisoning in U.S. (fpnotebook.com)
Food1
- Tests performed by the Food and Drug Administration (FDA) have not detected contamination with C. sordellii of either of the medications used in medical abortions. (cdc.gov)
Recent1
- CDC experts in microbiology, epidemiology, and perinatology (pregnancy-related complications) are working together with state and local health agencies and the FDA in the investigation of recent deaths associated with C. sordellii . (cdc.gov)
Women1
- Researchers continue to study what percentage of women carries vaginal or rectal C. sordellii and C. perfringens before and after abortion, as well as during pregnancy. (cdc.gov)