A species of gram-positive, strongly proteolytic bacteria in the family Clostridiaceae. It contains several forms of COLLAGENASE whose action can lead to GAS GANGRENE in humans and HORSES.
A genus of motile or nonmotile gram-positive bacteria of the family Clostridiaceae. Many species have been identified with some being pathogenic. They occur in water, soil, and in the intestinal tract of humans and lower animals.
A fibromatosis of the palmar fascia characterized by thickening and contracture of the fibrous bands on the palmar surfaces of the hand and fingers. It arises most commonly in men between the ages of 30 and 50.
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
Enzymes that catalyze the degradation of collagen by acting on the peptide bonds.
A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.
A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).
Infections with bacteria of the genus CLOSTRIDIUM.
A species of anaerobic, gram-positive, rod-shaped bacteria in the family Clostridiaceae that produces proteins with characteristic neurotoxicity. It is the etiologic agent of BOTULISM in humans, wild fowl, HORSES; and CATTLE. Seven subtypes (sometimes called antigenic types, or strains) exist, each producing a different botulinum toxin (BOTULINUM TOXINS). The organism and its spores are widely distributed in nature.

A novel galactooligosaccharide mixture increases the bifidobacterial population numbers in a continuous in vitro fermentation system and in the proximal colonic contents of pigs in vivo. (1/23)

Prebiotics are nondigestible food ingredients that encourage proliferation of selected groups of the colonic microflora, thereby altering the composition toward a more beneficial community. In the present study, the prebiotic potential of a novel galactooligosaccharide (GOS) mixture, produced by the activity of galactosyltransferases from Bifidobacterium bifidum 41171 on lactose, was assessed in vitro and in a parallel continuous randomized pig trial. In situ fluorescent hybridization with 16S rRNA-targeted probes was used to investigate changes in total bacteria, bifidobacteria, lactobacilli, bacteroides, and Clostridium histolyticum group in response to supplementing the novel GOS mixture. In a 3-stage continuous culture system, the bifidobacterial numbers for the first 2 vessels, which represented the proximal and traverse colon, increased (P < 0.05) after the addition of the oligosaccharide mixture. In addition, the oligosaccharide mixture strongly inhibited the attachment of enterohepatic Escherichia coli (P < 0.01) and Salmonella enterica serotype Typhimurium (P < 0.01) to HT29 cells. Addition of the novel mixture at 4% (wt:wt) to a commercial diet increased the density of bifidobacteria (P < 0.001) and the acetate concentration (P < 0.001), and decreased the pH (P < 0.001) compared with the control diet and the control diet supplemented with inulin, suggesting a great prebiotic potential for the novel oligosaccharide mixture.  (+info)

Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children. (2/23)

Children with autistic spectrum disorders (ASDs) tend to suffer from severe gastrointestinal problems. Such symptoms may be due to a disruption of the indigenous gut flora promoting the overgrowth of potentially pathogenic micro-organisms. The faecal flora of patients with ASDs was studied and compared with those of two control groups (healthy siblings and unrelated healthy children). Faecal bacterial populations were assessed through the use of a culture-independent technique, fluorescence in situ hybridization, using oligonucleotide probes targeting predominant components of the gut flora. The faecal flora of ASD patients contained a higher incidence of the Clostridium histolyticum group (Clostridium clusters I and II) of bacteria than that of healthy children. However, the non-autistic sibling group had an intermediate level of the C. histolyticum group, which was not significantly different from either of the other subject groups. Members of the C. histolyticum group are recognized toxin-producers and may contribute towards gut dysfunction, with their metabolic products also exerting systemic effects. Strategies to reduce clostridial population levels harboured by ASD patients or to improve their gut microflora profile through dietary modulation may help to alleviate gut disorders common in such patients.  (+info)

Crystallization and preliminary X-ray characterization of the catalytic domain of collagenase G from Clostridium histolyticum. (3/23)

 (+info)

Unidirectional binding of clostridial collagenase to triple helical substrates. (4/23)

 (+info)

A universal strategy for high-yield production of soluble and functional clostridial collagenases in E. coli. (5/23)

 (+info)

Injectable collagenase clostridium histolyticum for Dupuytren's contracture. (6/23)

 (+info)

Inhibitive effects of alkyl gallates on hyaluronidase and collagenase. (7/23)

A series of the gallate esters of n-alkanols (C(1)-C(12)) was examined to determine their inhibitory activities against hyaluronidase and collagenase. Hexyl, heptyl, octyl, nonyl, and decyl gallates inhibited both hyaluronidase and collagenase, and the most potent inhibitor was octyl gallate against both enzymes. Octyl 3,5-dihydroxybenzoate showed inhibitory effects on hyaluronidase, whereas collagenase was inhibited by octyl 3,4-dihydroxybenzoate.  (+info)

Tissue dissociation enzyme neutral protease assessment. (8/23)

 (+info)

The cause of Dupuytren contracture is not fully understood, but it is believed to be related to genetic factors and may be more common in people of Northern European ancestry. Other risk factors include a family history of the condition, alcoholism, diabetes, and liver or kidney disease.

The symptoms of Dupuytren contracture can progress slowly over time, with the fingers gradually becoming more bent and rigid. In some cases, the contracture can become severe enough to interfere with hand function and daily activities. Treatment options for Dupuytren contracture include physical therapy, splints, and surgery.

Surgery is often recommended for people with severe contractures or those who have significant difficulty with hand function. The goal of surgery is to release the contracted tissue and restore normal hand movement. However, surgery is not always successful, and recurrence of the contracture is common.

In addition to surgery, other treatment options for Dupuytren contracture include:

* Physical therapy to improve hand function and range of motion
* Splints to help straighten the fingers
* Injections of enzymes or other medications to dissolve the contracted tissue
* Radiofrequency ablation to heat and shrink the contractured tissue

It is important to note that Dupuytren contracture is a chronic condition, meaning it cannot be cured and will require ongoing treatment and monitoring. With proper treatment and management, however, many people with Dupuytren contracture are able to maintain functional use of their hands and improve their quality of life.

Some common types of Clostridium infections include:

* Clostridium difficile (C. diff) infection: This is a common type of diarrheal disease that can occur after taking antibiotics, especially in people who are hospitalized or living in long-term care facilities.
* Gas gangrene: This is a severe and potentially life-threatening infection that occurs when Clostridium bacteria infect damaged tissue, causing gas to build up in the affected area.
* Tetanus: This is a serious neurological infection caused by the bacterium Clostridium tetani, which can enter the body through open wounds or puncture wounds.
* Botulism: This is a potentially fatal illness caused by the bacterium Clostridium botulinum, which can be contracted through contaminated food or wounds.

Clostridium infections can cause a range of symptoms, including diarrhea, fever, abdominal pain, and swelling or redness in the affected area. Treatment depends on the type of infection and may include antibiotics, surgery, or supportive care to manage symptoms.

Prevention measures for Clostridium infections include proper hand hygiene, avoiding close contact with people who are sick, and practicing safe food handling practices to prevent the spread of botulism and other clostridial infections. Vaccines are also available for some types of clostridial infections, such as tetanus and botulism.

In summary, Clostridium infections are a diverse group of bacterial infections that can cause a range of illnesses, from mild to severe and life-threatening. Proper prevention and treatment measures are essential to avoid the potential complications of these infections.

... is an enzyme produced by the bacterium Clostridium histolyticum that dismantles collagen. ... Xiapex (Collagenase Clostridium Histolyticum) Authorised In The European Union For Dupuytren's Contracture, Medical News Today ... Xiapex: collagenase clostridium histolyticum, European Medicines Agency, Undated.Accessed: 20 March 2011. ... "Collagenase ColH of Hathewaya histolytica (Clostridium histolyticum) [Q46085]". UniProt. Retrieved 26 December 2020. "FDA ...
... (formerly Clostridium histolyticum) is a species of bacteria found in feces and the soil. It is a motile ... reclassified it as Clostridium histolyticum. Hathewaya histolytica can be isolated from soil during the early stage of soil ... Collagenase clostridium histolyticum is manufactured and marketed by Endo Pharmaceuticals in the US, and marketed by SOBI in ... Collagenase clostridium histolyticum is secreted by the bacterium and can destroy connective tissue of muscles. This ...
... (EC 3.4.11.13, Clostridium histolyticum aminopeptidase) is an enzyme. This enzyme catalyses the ... Kessler E, Yaron A (January 1973). "A novel aminopeptidase from Clostridium histolyticum". Biochemical and Biophysical Research ... Kessler E, Yaron A (March 1976). "An extracellular aminopeptidase from Clostridium histolyticum". European Journal of ... Kessler E, Yaron A (1976). "Extracellular aminopeptidase from Clostridium histolyticum". Methods in Enzymology. 45: 544-52. doi ...
It was isolated from Clostridium histolyticum. The isoelectric point of the enzyme is 4.8-4.9 (at 8 °C), and optimum pH is 7.4~ ... Clostripain (EC 3.4.22.8, clostridiopeptidase B, clostridium histolyticum proteinase B, alpha-clostridipain, ...
... difficile, now placed in Clostridioides. Clostridium histolyticum, now placed in Hathewaya. Clostridium sordellii, ... Mixtures of Clostridium species, such as Clostridium beijerinckii, Clostridium butyricum, and species from other genera have ... Clostridium welchii and Clostridium tetani respond to sulfonamides. Clostridia are also susceptible to tetracyclines, ... Clostridium histolyticum has been used as a source of the enzyme collagenase, which degrades animal tissue. Clostridium species ...
October 2015). "Collagenase clostridium histolyticum for the treatment of Dupuytren's contracture: systematic review and ... Bayat, Ardeshir; Thomas (2010). "The emerging role of Clostridium histolyticum collagenase in the treatment of Dupuytren ... "Injectable Collagenase Clostridium Histolyticum for Dupuytren's Contracture". New England Journal of Medicine. 361 (10): 968-79 ... "Collagenase Clostridium Histolyticum Injection: MedlinePlus Drug Information". medlineplus.gov. "Dupuytren's Interventions: ...
Bond MD, Van Wart HE (June 1984). "Relationship between the individual collagenases of Clostridium histolyticum: evidence for ... Bond MD, Van Wart HE (June 1984). "Characterization of the individual collagenases from Clostridium histolyticum". Biochemistry ... Microbial collagenase (EC 3.4.24.3, Clostridium histolyticum collagenase, clostridiopeptidase A, collagenase A, collagenase I, ... Clostridium histolyticum proteinase A, clostridiopeptidase II, MMP-8, clostridiopeptidase I, collagen peptidase, collagen ...
Clostridium histolyticum is a pathogen that causes gas gangrene; nevertheless, the isolated collagenase has been used to treat ... Collagen cleavage occurs at an Xaa+Got in Vibrio bacteria and at Yaa+Gly bonds in Clostridium collagenases.[citation needed] ... They assist in destroying extracellular structures in the pathogenesis of bacteria such as Clostridium. They are considered a ... Microbial collagenases have been identified from bacteria of both the Vibrio and Clostridium genera. Collagenase is used during ...
These enzymes are derived from micro-organisms including Clostridium histolyticum; or from plants, examples include collagenase ...
Genus Caloramator: Clostridium fervidum, reassigned in 1994. Genus Hathewaya: Clostridium histolyticum, C. limosum and C. ... Clostridium aceticum Clostridium acetireducens Clostridium acetobutylicum Clostridium acidisoli Clostridium aciditolerans ... Clostridium aestuarii Clostridium akagii Clostridium algidicarnis Clostridium algifaecis Clostridium algoriphilum Clostridium ... Clostridium novyi Clostridium oceanicum Clostridium oryzae Clostridium paradoxum Clostridium paraputrificum Clostridium pascui ...
In 1950, she became the first scientist to extract collagenase from the bacterium Clostridium histolyticum. Other work involved ...
Collagenase clostridium histolyticum is reported to help by breaking down the excess collagen in the penis. It was approved for ...
Excessive Clostridia spp. was found in children with ASD and gastrointestinal difficulties; Clostridia spp produces propionic ... Specifically, C. tetani and C. histolyticum are two species of this bacteria that affect people with ASD. C. tetani produces ... tetanus neurotoxin in the intestinal tract; C. histolyticum is a toxin producer that is abundant in people diagnosed with ASD. ...
"Analysis of the clinical safety of intralesional injection of collagenase Clostridium histolyticum (CCH) for adults with ...
Options for intervention include radiation therapy, cryosurgery, treatment with collagenase clostridium histolyticum, or ...
Salmonella typhimurium C. butyricum C. tetani C. histolyticum 17 and 18 C. beijerinckii 19 C. acetobutylicum C. sporogenes ... Clostridium novyi-NT is an attenuated form of Clostridium novyi that is under investigation as a cancer treatment. It is one of ... Among the various Clostridium strains that have been examined, pathogenic strains have a stronger oncolytic effect than others ... In 2014, researchers found that a modified strain of Clostridium novyi bacteria caused tumor shrinkage without damaging normal ...
Originally, Parker and co-workers showed that the injection of Clostridium histolyticum spores to the transplanted sarcomas of ... Nuyts S, Van Mellaert L, Theys J, Landuyt W, Lambin P, Anné J (February 2002). "Clostridium spores for tumor-specific drug ... CDEPT is the use of Clostridia to convert prodrugs into active drug agents. CDEPT exploits the hypoxic environment of solid ... Malmgren RA, Flanigan CC (August 1955). "Localization of the vegetative form of Clostridium tetani in mouse tumors following ...
... collagenase clostridium histolyticum (USAN) Colocort Colonaid Colovage colterol (INN) Coly-Mycin M Coly-Mycin S Colyte ...
Collagenase clostridium histolyticum (for Dupuytren's disease) In 2019, RSOM received over 4,800 applications for 136 seats. ...
Clostridium histolyticum-derived collagenases used for skin regeneration, and Microsporum-derived keratinases used for hair ...
... combinations with psycholeptics M09AB01 Chymopapain M09AB02 Collagenase clostridium histolyticum M09AB03 Bromelains M09AB52 ...
... clostridium difficile MeSH B03.300.390.400.200.412 - Clostridium histolyticum MeSH B03.300.390.400.200.493 - Clostridium ... Clostridium difficile MeSH B03.510.415.400.200.412 - Clostridium histolyticum MeSH B03.510.415.400.200.493 - Clostridium ... Clostridium botulinum type G MeSH B03.300.390.400.200.180 - Clostridium butyricum MeSH B03.300.390.400.200.200 - Clostridium ... Clostridium botulinum type G MeSH B03.510.415.400.200.180 - Clostridium butyricum MeSH B03.510.415.400.200.200 - Clostridium ...
Collagenase Clostridium histolyticum Injection: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Collagenase Clostridium histolyticum injection comes as a powder to be mixed with a liquid and injected by a doctor. If you are ... Collagenase Clostridium histolyticum Injection. pronounced as (kol a jen ase) (klos trid ee um) (his toe lit ik um) ... Collagenase Clostridium histolyticum injection may cause side effects. Tell your doctor if any of these symptoms are severe or ...
... collagenase clostridium histolyticum), or request a representative for assistance. See safety information, including tendon ... You are about to leave the XIAFLEX® (collagenase clostridium histolyticum) website.. You are now leaving the XIAFLEX® website. ...
Collagenase clostridium histolyticum (Xiaflex). Skin necrosis. FDA is evaluating the need for regulatory action.. ...
Clostridium histolyticum. A component of the NCIS kit. This material is 0.22 micron membrane filtered and lyophilized in ...
McGuigan CC, Penrice GM, Gruer L, Ahmed S, Goldberg D, Black M, Lethal outbreak of infection with Clostridium novyi type A and ... histolyticum, and C. perfringens, were isolated from injection site wounds of 3 patients. A heroin sample from 1 patient was ... Clostridium tetani was isolated from 2 patients; tetanus toxin was detected in serum from 1 and also from another patient. ... The reasons for emergence of Clostridium infections in IDUs in the United Kingdom remain speculative (9). They include an ...
Intralesional Injection of Collagenase Clostridium histolyticum May Increase the Risk of Late-Onset Penile Fracture. Sexual ... Analysis of the clinical safety of intralesional injection of collagenase Clostridium histolyticum (CCH) for adults with ...
Intralesional collagenase clostridium histolyticum (marketed as Xiaflex®) may be helpful.. Surgery is probably the best ...
Clostridium histolyticum Collagenase, Rabbit anti. Catalog #: YNNE0427S. Rabbit Host. Price: $ 415.00. Packing: 10 mg ...
Limited success with clostridium collagenase histolyticum following FDA approval for the treatment of Peyronies disease. Int J ... Abdel Raheem A, Johnson M, Abdel-Raheem T, Capece M, Ralph D. Collagenase Clostridium histolyticum in the Treatment of ... Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 ... Predictors of treatment success after collagenase Clostridium histolyticum injection for Peyronies disease: development of a ...
Collagenase clostridium histolyticum (1). * Crisantaspase (1). * Cyclopentolate (1). * Daptomycin (1). * Darbepoetin alfa (1). ...
Clostridium histolyticum - Preferred Concept UI. M0456150. Scope note. A species of gram-positive, strongly proteolytic ... Clostridium histolyticum. Scope note:. Especie de bacteria grampositiva muy proteolítica de la familia Clostridiaceae. Contiene ... infection: coordinate IM with CLOSTRIDIUM INFECTIONS (IM) or GAS GANGRENE (IM) if appropriate. ... Clostridium histolyticum Descriptor Spanish: Clostridium histolyticum Spanish from Spain Descriptor. ...
Xiaflex (collagenase clostridium histolyticum) is the first drug to be approved in the US to treat a progressive hand disease ... Xiaflex, made from the protein product of a species of the bacterium Clostridium, is the first non-surgical therapy for ...
Clostridium histolyticum, Rickettsia spp., and Leptospira inadai. CONCLUSIONS: Abundant bacterial endosymbionts, such as CMM, ...
Clostridium histolyticum, C. lituseburense and Faecalibacterium prausnitzii, an increase of B ... [retrieve this message] ...
Collagenase clostridium histolyticum. Example Trade Names. Xiapex. Context. Status. Red. Guidance. New Entry. ...
collagenase clostridium histolyticum * eflapegrastim * daratumumab/hyaluronidase Drug Interaction Checker Recommendations. * ...
Refer to Medical Policy I-107, Injectable Collagenase Clostridium Histolyticum, for additional information. ...
Clostridium chauvoei B3.353.625.500.215 Clostridium difficile B3.353.625.500.250 Clostridium histolyticum B3.353.625.500.412 ... Clostridium B3.353.625.500 Clostridium acetobutylicum B3.353.625.500.25 Clostridium beijerinckii B3.353.625.500.100 Clostridium ... Clostridium botulinum type A B3.353.625.500.160.50 Clostridium botulinum type B B3.353.625.500.160.100 Clostridium botulinum ... Clostridium botulinum type E B3.353.625.500.160.250 Clostridium botulinum type F B3.353.625.500.160.300 Clostridium botulinum ...
What is QWO™collagenase ccollagenase clostridium histolyticum-aaes)? It is an injectable medication which is FDA approved for ... How does QWO ™( collagenasecollagenase clostridium histolyticum-aaes) work?. It destroys those fibrous septae which cause skin ... How many QWO ™( collagenaseccollagenase clostridium histolyticum-aaes) does one need?. The treatment consists of 3 treatment ... What to expect during your QWO ™( collagenaseccollagenase clostridium histolyticum-aaes) treatment?. Once deemed a candidate ...
Pain Associated With Treatment of Dupuytren Contracture With Collagenase Clostridium histolyticum.. Sanjuan-Cerveró R, Carrera- ...
Clostridium histolyticum;collagenase;internally quenched fluorescent substrate;MALDI mass spectrometry;circular dichroism.. ... The substrate is cleaved exclusively by Clostridium histolyticum collagenase and is completely resistant to attack by proteases ...
Outbreak of Clostridium histolyticum infections in injecting drug users in England and Scotland. Eurosurveillance 9(9), pp. 15- ... Outbreak of Clostridium histolyticum infections in injecting drug users in England and Scotland. Eurosurveillance 9(9), pp. 15- ... Subtyping of Clostridium difficile PCR ribotype 001 by REP-PCR and PFGE. Journal of Medical Microbiology 54(Pt6), pp. 543-547 ... Subtyping of Clostridium difficile PCR ribotype 001 by REP-PCR and PFGE. Journal of Medical Microbiology 54(Pt6), pp. 543-547 ...
Qwo (collagenase clostridium histolyticum-aaes) is the first FDA approved injectable treatment for cellulite. It is indicated ...
Treatment with PRP+ASC reduced the ratio, but collagenase Clostridium histolyticum did not. CONCLUSIONS: Treating DMFs with PRP ... ASCs and collagenase Clostridium histolyticum treatments. DMFs induce collagen I and III expressions in rat paws compared with ... or collagenase Clostridium histolyticum (clinical comparison) 2 months later. After 2 weeks, the tissue was harvested and ...
Injections of Collagenase Clostridium histolyticum (CCh) can be an effective way to treat men with Peyronies disease. But in ... For men with Peyronies disease, treatment with collagenase clostridium histolyticum (CCH) has become more popular over the ...
The only FDA-approved medication for Peyronies disease is collagenase clostridium histolyticum (called by its brand-name, ...
Prevotella and Clostridium Histolyticum. ...
... have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and ...
Qwo (collagenaseccollagenase clostridium histolyticum-aaes) is the first and only FDA-approved injectable for moderate to ...
... capsules with deviceCOLISTIMETHATE SODIUM powder for solution for injection or nebulisationCOLLAGENASE CLOSTRIDIUM HISTOLYTICUM ...
  • Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with collagenase Clostridium histolyticum (Xiaflex) and each time you receive the medication. (medlineplus.gov)
  • Talk to your doctor about the risks of receiving collagenase Clostridium histolyticum injection (Xiaflex). (medlineplus.gov)
  • Collagenase Clostridium histolyticum injection (Xiaflex) is used to treat Dupuytren's contracture (a painless thickening and tightening of tissue [cord] beneath the skin in the palm of the hand, which may make it difficult to straighten one or more fingers) when a cord of tissue can be felt upon examination. (medlineplus.gov)
  • Collagenase Clostridium histolyticum injection (Xiaflex) is also used to treat Peyronie's disease (a thickening of tissue [plaque] inside the penis that causes the penis to curve). (medlineplus.gov)
  • Collagenase Clostridium histolyticum injection (QWO) is also used to treat cellulite (fat deposit beneath the skin) in the buttocks of adult women. (medlineplus.gov)
  • Collagenase Clostridium histolyticum injection is in a class of medications called enzymes. (medlineplus.gov)
  • Collagenase Clostridium histolyticum injection comes as a powder to be mixed with a liquid and injected by a doctor. (medlineplus.gov)
  • If you are receiving collagenase Clostridium histolyticum injection (Xiaflex) to treat Dupuytren's contracture, your doctor will inject the medicine into a cord just under the skin in the affected hand. (medlineplus.gov)
  • If you are receiving collagenase Clostridium histolyticum injection (Xiaflex) to treat Peyronie's disease, your doctor will inject the medicine into the plaque that is causing your penis to curve. (medlineplus.gov)
  • If you are receiving collagenase Clostridium histolyticum (QWO) to treat cellulite, your doctor will inject it subcutaneously (just under the skin) into the buttock(s). (medlineplus.gov)
  • If you are receiving treatment for Peyronie's disease, your doctor will inject collagenase Clostridium histolyticum into your penis, followed by a second injection 1 to 3 days after the first injection. (medlineplus.gov)
  • Intralesional collagenase clostridium histolyticum (marketed as Xiaflex ® ) may be helpful. (dermnetnz.org)
  • Xiaflex (collagenase clostridium histolyticum) is the first drug to be approved in the US to treat a progressive hand disease known as Dupuytren's contracture. (battlingforhealth.com)
  • Injections of Collagenase Clostridium histolyticum (CCh) can be an effective way to treat men with Peyronie's disease. (smsna.org)
  • For men with Peyronie's disease, treatment with collagenase clostridium histolyticum (CCH) has become more popular over the years. (smsna.org)
  • The only FDA-approved medication for Peyronie's disease is collagenase clostridium histolyticum (called by its brand-name, Xiaflex ). (houstonmenshealth.com)
  • Serious injury to the penis, including penile fracture (corporal rupture), has been reported in patients receiving Clostridium histolyticum injection (Xiaflex) for treatment of Peyronie's disease. (medlineplus.gov)
  • Xiaflex, made from the protein product of a species of the bacterium Clostridium, is the first non-surgical therapy for Dupuytren's contracture, a disease common in Caucasian men over 50. (battlingforhealth.com)
  • Qwo (collagenaseccollagenase clostridium histolyticum-aaes) is the first and only FDA-approved injectable for moderate to severe cellulite in the buttocks of adult women. (happycliniccos.com)
  • Other anaerobes, including C . novyi , C . histolyticum , and C . perfringens , were isolated from injection site wounds of 3 patients. (cdc.gov)
  • 005.0 Staphylococcal food poisoning Staphylococcal toxaemia specified as due to food 005.1 Botulism Food poisoning due to Clostridium botulinum 005.2 Food poisoning due to Clostridium perfringens [Cl. (cdc.gov)
  • Type species of the genus CLOSTRIDIUM, a gram-positive bacteria in the family Clostridiaceae. (bvsalud.org)
  • Clostridium glycyrrhizinilyticum is the correct name if this species is regarded as a separate species (i.e., if its nomenclatural type is not assigned to another species whose name is validly published, legitimate and not rejected and has priority) within a separate genus Clostridium . (dsmz.de)
  • The Food and Drug Administration has approved collagenase clostridium histolyticum-aaes (Qwo, Endo International) for the treatment of moderate to severe cellulite in the buttocks of adult women. (medscape.com)
  • Cite this: FDA Approves Collagenase Clostridium Histolyticum-aaes for Cellulite - Medscape - Jul 09, 2020. (medscape.com)
  • Other anaerobes, including C . novyi , C . histolyticum , and C . perfringens , were isolated from injection site wounds of 3 patients. (cdc.gov)
  • This was also found in a large international outbreak of C . novyi in IDUs ( 7 ) and a botulism outbreak in IDUs in California ( 6 ), and is consistent with the obligate anaerobe characteristic of Clostridium spp. (cdc.gov)
  • Collagenase Clostridium histolyticum injection (QWO) is also used to treat cellulite (fat deposit beneath the skin) in the buttocks of adult women. (medlineplus.gov)
  • If you are receiving collagenase Clostridium histolyticum (QWO) to treat cellulite, your doctor will inject it subcutaneously (just under the skin) into the buttock(s). (medlineplus.gov)
  • If you are receiving treatment for Peyronie's disease, your doctor will inject collagenase Clostridium histolyticum into your penis, followed by a second injection 1 to 3 days after the first injection. (medlineplus.gov)
  • Collagenase Clostridium histolyticum injection comes as a powder to be mixed with a liquid and injected by a doctor. (medlineplus.gov)
  • Single-use glass vials containing 0.9 mg of collagenase clostridium histolyticum as a sterile, lyophilized powder for reconstitution. (nih.gov)
  • 2. Injectable Clostridium histolyticum collagenase as a potential treatment for uterine fibroids. (nih.gov)