Cloacin: A bacteriocin produced by a plasmid that can occur in several bacterial strains. It is a basic protein of molecular weight 56,000 and exists in a complex with its immunity protein which protects the host bacterium from its effects.Bacteriocins: Substances elaborated by specific strains of bacteria that are lethal against other strains of the same or related species. They are protein or lipopolysaccharide-protein complexes used in taxonomy studies of bacteria.Enterobacter: Gram-negative gas-producing rods found in feces of humans and other animals, sewage, soil, water, and dairy products.Mitomycins: A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.Iron Chelating Agents: Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems.Bacteriocin Plasmids: Plasmids encoding bacterial exotoxins (BACTERIOCINS).Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Hydroxamic Acids: A class of weak acids with the general formula R-CONHOH.Bacterial Outer Membrane Proteins: Proteins isolated from the outer membrane of Gram-negative bacteria.Bacterial Proteins: Proteins found in any species of bacterium.Plasmids: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.Receptors, Immunologic: Cell surface molecules on cells of the immune system that specifically bind surface molecules or messenger molecules and trigger changes in the behavior of cells. Although these receptors were first identified in the immune system, many have important functions elsewhere.Rhinoscleroma: A granulomatous disease caused by KLEBSIELLA RHINOSCLEROMATIS infection. Despite its name, this disease is not limited to the nose and NASOPHARYNX but may affect any part of the RESPIRATORY TRACT, sometimes with extension to the lip and the skin.Klebsiella pneumoniae: Gram-negative, non-motile, capsulated, gas-producing rods found widely in nature and associated with urinary and respiratory infections in humans.Preservatives, Pharmaceutical: Substances added to pharmaceutical preparations to protect them from chemical change or microbial action. They include ANTI-BACTERIAL AGENTS and antioxidants.Klebsiella Infections: Infections with bacteria of the genus KLEBSIELLA.Quality Control: A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)Parabens: Methyl, propyl, butyl, and ethyl esters of p-hydroxybenzoic acid. They have been approved by the FDA as antimicrobial agents for foods and pharmaceuticals. (From Hawley's Condensed Chemical Dictionary, 11th ed, p872)Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).Bacteriology: The study of the structure, growth, function, genetics, and reproduction of bacteria, and BACTERIAL INFECTIONS.Iron: A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.Proton-Motive Force: Energy that is generated by the transfer of protons or electrons across an energy-transducing membrane and that can be used for chemical, osmotic, or mechanical work. Proton-motive force can be generated by a variety of phenomena including the operation of an electron transport chain, illumination of a PURPLE MEMBRANE, and the hydrolysis of ATP by a proton ATPase. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed, p171)Siderophores: Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994)Ferrichrome: A cyclic peptide consisting of three residues of delta-N-hydroxy-delta-N-acetylornithine. It acts as an iron transport agent in Ustilago sphaerogena.Enterobactin: An iron-binding cyclic trimer of 2,3-dihydroxy-N-benzoyl-L-serine. It is produced by E COLI and other enteric bacteria.Colicins: Bacteriocins elaborated by strains of Escherichia coli and related species. They are proteins or protein-lipopolysaccharide complexes lethal to other strains of the same species.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Escherichia coli Proteins: Proteins obtained from ESCHERICHIA COLI.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Helping Behavior: Behaviors associated with the giving of assistance or aid to individuals.Language Development: The gradual expansion in complexity and meaning of symbols and sounds as perceived and interpreted by the individual through a maturational and learning process. Stages in development include babbling, cooing, word imitation with cognition, and use of short sentences.Research Support as Topic: Financial support of research activities.Research Design: A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.Language Disorders: Conditions characterized by deficiencies of comprehension or expression of written and spoken forms of language. These include acquired and developmental disorders.Ethics, Research: The moral obligations governing the conduct of research. Used for discussions of research ethics as a general topic.Markov Chains: A stochastic process such that the conditional probability distribution for a state at any future instant, given the present state, is unaffected by any additional knowledge of the past history of the system.Databases, Protein: Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.

Polymorphism in the aerobactin-cloacin DF13 receptor genes from an enteroinvasive strain of Escherichia coli and pColV-K30 is associated only with a decrease in cloacin susceptibility. (1/26)

We have cloned chromosomal genes mediating the aerobactin iron transport system from the enteroinvasive strain Escherichia coli 978-77. The physical map of the region spanning the siderophore biosynthesis genes and the upstream portion of the receptor gene in strain 978-77-derived clones was identical to the corresponding regions in pColV-K30, while the downstream portion was different. Recombinant plasmids derived from strain 978-77 encoded a 76-kDa outer membrane protein, in contrast to the 74-kDa polypeptide encoded by similar clones derived from pColV-K30. No differences were found in the uptake of ferric aerobactin mediated by either the 76-kDa- or the 74-kDa-encoding plasmids. In contrast, cells containing the 76-kDa-encoding plasmids showed a 16-fold decrease in susceptibility to cloacin compared with cells harboring the 74-kDa-encoding plasmids. Two classes of chimeric aerobactin receptor genes were constructed by exchanging sequences corresponding to the downstream portion from the aerobactin receptor gene of both systems. The pColV-K30-978-77 chimeric gene encoded a 76-kDa outer membrane protein which mediated a low level of cloacin susceptibility, whereas the 978-77-pColV-K30 type encoded a protein of 74 kDa determining a level of cloacin susceptibility identical to that mediated by pColV-K30.  (+info)

Production and excretion of cloacin DF13 by Escherichia coli harboring plasmid CloDF13. (2/26)

The production and the mechanism of excretion of cloacin DF13 were investigated in noninduced and mitomycin C-induced cell cultures. A mitomycin C concentration was selected which did not cause lysis of cloacinogenic cells, but at the same time induced a maximal production of cloacin DF13. Native cloacin DF13, possessing killing activity, was first released into the cytoplasm. Shortly thereafter, the bacteriocin was transported through the cytoplasmic membrane and accumulated in the periplasm. Finally, cloacin DF13 was excreted into the culture medium. A small amount of cloacin DF13 remained associated with the cell surface. Producing cells did not become permeable for the cytoplasmic enzyme beta-galactosidase. Apparently the cloacin DF13 leaves the producing cells by an excretion process which is not similar to the mechanism proposed for bacterial secretory proteins. The processes of excretion by producing cells and of uptake by susceptible cells were also not identical because mutant cloacin DF13, which was not transported through the outer membrane into susceptible cells, was excreted like the wild-type cloacin DF13. The composition of the culture medium greatly affected production of cloacin DF13. The presence of sugars known to cause catabolite repression not only inhibited the production but also strongly reduced the excretion of cloacin DF13 into the culture medium.  (+info)

Changes in protein synthesis on mitomycin C induction of wild-type and mutant CloDF13 plasmids. (3/26)

Mitomycin C treatment of Escherichia coli K-12 cells containing the nonconjugative plasmid CloDF13 resulted in inhibition of host chromosome protein synthesis and a high rate of synthesis of two CloDF13-specified proteins whose molecular weights correspond to cloacin and immunity protein. Five molecules of immunity protein were synthesized for each cloacin DF13 molecule. Mitomycin C-treated cells containing a copy mutant of CloDF13 made three to four times as much of each protein as cells containing wild-type CloDF13. CloDF13 plasmids that contained the transposon Tn1 were isolated. Two did not induce after mitomycin C treatment, failing both to inhibit host cell synthesis and to produce the two new proteins. In minicells, they showed reduced CloDF13-specified protein synthesis and produced three Tn1-specified proteins.  (+info)

Uptake of cloacin DF13 by susceptible cells: removal of immunity protein and fragmentation of cloacin molecules. (4/26)

Monoclonal antibodies (MAb) directed against different epitopes on the equimolar complex of cloacin and immunity protein (cloacin DF13) were isolated, characterized, and used to study the uptake of cloacin DF13 by susceptible cells. Four MAbs recognized the amino-terminal part, one MAb recognized the central part, and three MAbs recognized the carboxyl-terminal part of the cloacin molecule. Three MAbs reacted with the immunity protein. Five MAbs inhibited the lethal action of cloacin DF13, but none of the MAbs inhibited the binding of cloacin DF13 to its purified outer membrane receptor protein or the in vitro inactivation of ribosomes. Binding of cloacin DF13 to susceptible cells cultured in broth resulted in a specific, time-dependent dissociation of the complex and a fragmentation of the cloacin molecules. Increasing amounts of immunity protein were detected in the culture medium from about 20 min after the addition of cloacin DF13. Cloacin was fragmented into two carboxyl-terminal fragments with relative molecular masses of 50,000 and 10,000. The larger fragment was detected 5 min after the binding of the bacteriocin complex to the cells. The smaller fragment was detected after 10 min. Both fragments were associated with the cells and could not be detected in the culture supernatant fraction. Cells grown in brain heart infusion were much less susceptible to cloacin DF13 than cells grown in broth, although they possessed a similar number of outer membrane receptor molecules. This decreased susceptibility correlated with a decreased translocation, dissociation, and fragmentation of cloacin DF13.  (+info)

Methylation-dependent transcription controls plasmid replication of the CloDF13 cop-1(Ts) mutant. (5/26)

The CloDF13 cop-1(Ts) mutant expresses a temperature-dependent plasmid copy number. At 42 degrees C the mutant shows a "runaway" behavior, and cells harboring this plasmid are killed. The cop-1(Ts) mutation is a G-to-A transition that disturbs one of the two methylation sites which are located opposite in the stem-loop structure within a region involved in both the initiation of primer synthesis for DNA replication and the termination of the cloacin operon transcript. We demonstrate that the mutation results in an increased primer (RNA II) synthesis resulting from nonconditional enhanced RNA II promoter activity, which at 42 degrees C causes a decrease in the amount of active replication repressor molecules (RNA I) synthesized from the opposite strand. We found that the absence of Dam methylation abolishes the mutant phenotype and that under this condition the high mutant level of RNA II synthesis is reduced, which is accompanied by a restoration of the regulation by RNA I. The role of methylation in the regulation of plasmid replication is discussed.  (+info)

Expression in Escherichia coli K-12 of the 76,000-dalton iron-regulated outer membrane protein of Shigella flexneri confers sensitivity to cloacin DF13 in the absence of Shigella O antigen. (6/26)

One of the chromosomal segments associated with virulence in Shigella flexneri encodes the production of aerobactin and the synthesis of an iron-regulated 76-kilodalton outer membrane protein believed to be the ferric-aerobactin receptor. However, S. flexneri expressing this putative aerobactin receptor, which is slightly larger than that encoded by pColV, is insensitive to the killing action of cloacin DF13, a bacteriocin which binds to other aerobactin receptor proteins and kills the cells. In this paper we show that the conjugal transfer of DNA encoding the iron-regulated 76-kilodalton protein from S. flexneri to Escherichia coli K-12 conferred cloacin DF13 sensitivity on the recipients. However, E. coli K-12 which had also inherited genes specifying Shigella O-antigen biosynthesis remained cloacin insensitive. The data suggest that it is unwise to use cloacin DF13 sensitivity alone to screen transconjugants or clinical isolates for the expression of aerobactin receptor proteins.  (+info)

Novel aerobactin receptor in Klebsiella pneumoniae. (7/26)

Several Klebsiella pneumoniae strains which produced enterochelin but not aerobactin were nevertheless sensitive to cloacin DF13. In contrast, a strain of serotype K1:O1 which produced both siderophores was cloacin-resistant. Loss by mutation of the O1 but not K1 antigen rendered this strain cloacin-sensitive, indicating that the O1 antigen prevented access of cloacin to the cloacin/aerobactin receptor. Unlike the K1:O1 strain, the aerobactin-negative strains failed to hybridize in a colony blot assay with an aerobactin receptor gene probe prepared from pColV-K30. However, antisera raised against the 74 kDa pColV-K30 aerobactin receptor cross-reacted with a 76 kDa outer-membrane protein in each K. pneumoniae strain. In addition to the 76 kDa protein, the K1:O1 strain also produced a strongly cross-reacting 74 kDa protein. To determine whether these aerobactin-negative strains could use aerobactin, mutants unable to synthesize siderophores were isolated. Aerobactin promoted the growth of these mutants in iron-deficient media. The evidence presented suggests that some K. pneumoniae strains produce an aerobactin iron-uptake system without apparent production of aerobactin and which is probably based on a 76 kDa receptor, the gene for which does not hybridize with aerobactin receptor gene encoded on pColV-K30.  (+info)

pCloDF13-encoded bacteriocin release proteins with shortened carboxyl-terminal segments are lipid modified and processed and function in release of cloacin DF13 and apparent host cell lysis. (8/26)

By oligonucleotide-directed mutagenesis, stop codon mutations were introduced at various sites in the pCloDF13-derived bacteriocin release protein (BRP) structural gene. The expression, lipid modification (incorporation of [3H]palmitate), and processing (in the presence and absence of globomycin) of the various carboxyl-terminal shortened BRPs were analyzed by a special electrophoresis system and immunoblotting with an antiserum raised against a synthetic BRP peptide, and their functioning with respect to release of cloacin DF13, lethality, and apparent host cell lysis were studied in Sup-, supF, and supP strains of Escherichia coli. All mutant BRPs were stably expressed, lipid modified, and processed by signal peptidase II, albeit with different efficiencies. The BRP signal peptide appeared to be extremely stable and accumulated in induced cells. Full induction of the mutant BRPs, including the shortest containing only 4 amino acid residues of the mature polypeptide, resulted in phospholipase A-dependent and Mg2+-suppressible apparent cell lysis. The extent of this lysis varied with the mutant BRP used. Induction of all mutant BRPs also prevented colony formation, which appeared to be phospholipase A independent. One shortened BRP, containing 20 amino acid residues of the mature polypeptide, was still able to bring about the release of cloacin DF13. The results indicated that the 8-amino-acid carboxyl-terminal segment of the BRP contains a strong antigenic determinant and that a small segment between amino acid residues 17 and 21, located in the carboxyl-terminal half of the BRP, is important for release of cloacin DF13. Either the stable signal peptide or the acylated amino-terminal BRP fragments (or both) are involved in host cell lysis and lethality.  (+info)

*Cloacin immunity protein

In molecular biology, the cloacin immunity protein inhibits the bacterial polypeptide toxin, cloacin. It complexes with cloacin ... more immunity protein than cloacin is synthesised. Comparison of the complete amino acid sequence of the Clo DF13 immunity ... in equimolar quantities and inhibits it by binding with high affinity to the cloacin C-terminal catalytic domain. The immunity ...

*Colicin

Cloacin DF13 is a bacteriocin that inactivates ribosomes by hydrolysing 16S RNA in 30S ribosomes at a specific site. Because ...
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Gene expression analyses • Chromatin structure/function • Protein characterization and manipulation • Cell molecular architecture • Tumor virus molecular biology • Molecular mechanisms of ion channels and neurotransmitter release • Protein folding, structure and function • Molecular neurobiology • Developmental mechanisms • Proteomics • Detection of food-borne pathogens • Plant molecular biology and metabolism • Cardiovascular physiology and development • DNA repair and telomeres in cancer and aging • Prions in neurodegenerative diseases ...
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if(interactive()) curve(ptukey(x, nm=6, df=5), from=-1, to=8, n=101) (ptt ,- ptukey(0:10, 2, df= 5)) (qtt ,- qtukey(.95, 2, df= 2:11)) ## The precision may be not much more than about 8 digits: summary(abs(.95 - ptukey(qtt,2, df = 2:11 ...
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This is the Df used by Myster and Peifer (Genetics 166: 807-822, 2004); it is either Dorsetts Df(2R)Nipped-D263.3 or Df(2R)Nipped-D341.1, K.C ...
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Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival ...

Klebsiella pneumoniae subsp. pneumoniae (Schroeter) Trevisan ATCC ®Klebsiella pneumoniae subsp. pneumoniae (Schroeter) Trevisan ATCC ®

Nucleotide (GenBank) : AF190857 Klebsiella pneumoniae cloacin operon, complete sequence. Nucleotide (GenBank) : U67169 ...
more infohttps://www.atcc.org/en/Products/Quality_Control_Strains/Media_testing/13883.aspx?p=1&rel=%7B0%7D&slp=1

Cloacin immunity protein - WikipediaCloacin immunity protein - Wikipedia

In molecular biology, the cloacin immunity protein inhibits the bacterial polypeptide toxin, cloacin. It complexes with cloacin ... more immunity protein than cloacin is synthesised. Comparison of the complete amino acid sequence of the Clo DF13 immunity ... in equimolar quantities and inhibits it by binding with high affinity to the cloacin C-terminal catalytic domain. The immunity ...
more infohttps://en.wikipedia.org/wiki/Cloacin_immunity_protein

Application and assessment of cloacin typing of Enterobacter cloacae. - Semantic ScholarApplication and assessment of cloacin typing of Enterobacter cloacae. - Semantic Scholar

When all the isolates were typed by cloacin susceptibility, 81.5% of them were typable. Maximum discrimination between cultures ... Application and assessment of cloacin typing of Enterobacter cloacae.. @article{Daw1992ApplicationAA, title={Application and ... assessment of cloacin typing of Enterobacter cloacae.}, author={Mohamed A Daw and Gerard D. Corcoran and F. R. Falkiner and ...
more infohttps://www.semanticscholar.org/paper/Application-and-assessment-of-cloacin-typing-of-Daw-Corcoran/80ccf9027696e9d3f0ef448f3383f2fce79f7d6e

Colicins-Exocellular lethal proteins of Escherichia coli | SpringerLinkColicins-Exocellular lethal proteins of Escherichia coli | SpringerLink

Wooldridge K.G., Williams P.H.: Sensitivity ofEscherichia coli to cloacin DF13 involves the major outer membrane protein OmpF.J ... an evolutionary intermediate between E-group colicins and cloacin DF13.J. Bacteriol.171, 6430-6436 (1989).PubMedGoogle Scholar ...
more infohttps://link.springer.com/article/10.1007%2FBF02816372

Table of Contents | Journal of BacteriologyTable of Contents | Journal of Bacteriology

Purification and characterization of cloacin DF13 receptor from Enterobacter cloacae and its interaction with cloacin DF13 in ...
more infohttps://jb.asm.org/content/138/1

Colicin - WikipediaColicin - Wikipedia

Cloacin DF13 is a bacteriocin that inactivates ribosomes by hydrolysing 16S RNA in 30S ribosomes at a specific site. Because ...
more infohttps://en.wikipedia.org/wiki/Colicin

Kudos - helping increase the reach and impact of researchKudos - helping increase the reach and impact of research

tolQis required for cloacin DF13 susceptibility inEscherichia coliexpressing the aerobactin/cloacin DF13 receptor IutA. ... Diphenylamine increases cloacin DF13 sensitivity in avian septicemic strains of Escherichia coli. Published in:Veterinary ...
more infohttps://www.growkudos.com/profiles/11843

Molecular cloning and expression in Escherichia coli of the structural gene for the hemolytic toxin aerolysin from Aeromonas...Molecular cloning and expression in Escherichia coli of the structural gene for the hemolytic toxin aerolysin from Aeromonas...

De Graaf FK, Klassen-Boor P (1977) Purification and characterization of a complex between cloacin and its immunity protein ...
more infohttps://link.springer.com/article/10.1007/BF00425512

Gamma-SecretaseGamma-Secretase

Fig.1).1). This lag time is consistent with earlier observations for the release of colicin E2 (20), cloacin DF13 (14) and ...
more infohttp://www.academicediting.org/category/gamma-secretase/

Bacteriocins | Profiles RNSBacteriocins | Profiles RNS

Wickham SE, Hotze EM, Farrand AJ, Polekhina G, Nero TL, Tomlinson S, Parker MW, Tweten RK. Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9. J Biol Chem. 2011 Jun 10; 286(23):20952-62 ...
more infohttps://profiles.healthsciencessc.org/display/96017

The Galloway Chronicles: 2008The Galloway Chronicles: 2008

Rudimentary Plans For A New Altar To Venus Cloacin.... *Good Feng Shui/Bad Feng Shui? ...
more infohttp://thegallowaychronicles.blogspot.com/2008/

Colicin E3 immunity protein superfamilyColicin E3 immunity protein superfamily

The cloacin immunity protein complexes with cloacin in equimolar quantities and inhibits it by binding with high affinity to ... 6253914], which perhaps accounts for the fact that, in cloacinogenic cells, more immunity protein than cloacin is synthesised [ ... the cloacin C-terminal catalytic domain. The immunity protein is relatively small, containing 85 amino acids. An extra ribosome ...
more infohttp://supfam.cs.bris.ac.uk/SUPERFAMILY/cgi-bin/scop.cgi?sunid=54552

February | 2018 | SiRNA LibraryFebruary | 2018 | SiRNA Library

... cloacin) production (in pIGMS32; Fig. 1). Comparative sequence analysis (NCBI database) revealed that pIGMS32 is identical to a ...
more infohttps://sirna-library.com/2018/02

Aeqvitas PhotosAeqvitas Photos

... shrine of Venus Cloacina inscribed CLOACIN on which there are two statues of the goddess. Crawford 494/42c; Sear 188b; Sydenham ...
more infohttp://www.aeqvitas.com/photo.php?term=L.+Mussidius+Longus+&precanned=Roman_Republic

CNG: Feature Auction CNG 91. Moneyer issues of Imperatorial Rome. L. Mussidius Longus. 42 BC. AR Denarius (17mm, 3.99 g, 7h)....CNG: Feature Auction CNG 91. Moneyer issues of Imperatorial Rome. L. Mussidius Longus. 42 BC. AR Denarius (17mm, 3.99 g, 7h)....

Two statues of Venus Cloacina behind balustrade of platform inscribed CLOACIN with balustrade. Crawford 494/43a; CRI 189; ...
more infohttps://cngcoins.com/Coin.aspx?CoinID=216109

rdekess gek az illemhelyekr l: egy kis WC-t rt net - H ziPatikardekess gek az illemhelyekr l: egy kis WC-t rt net - H ziPatika

... mint a r maiak Cloacin t - istenk nt is tisztelik. A tr gya ugyanis minden f ldm vel t rsadalomban dr ga kincs. A k z pkori K n ...
more infohttps://www.hazipatika.com/eletmod/intim_higienia/cikkek/erdekessegek_az_illemhelyekrol_egy_kis_wc-tortenet/20070914154924

Buscar : Monedas,  Monedas Antiguas (650 B.C. to 1453 A.C), MonedasBuscar : Monedas, Monedas Antiguas (650 B.C. to 1453 A.C), Monedas

Below CLOACIN, legend: L MVSSIDIVS LONGVS Sear.... Monedas Monedas Antiguas (650 B.C. to 1453 A.C) Monedas Romanas Republic (- ...
more infohttps://www.colleconline.com/es/Search/ByPle/feae0c33-33f9-40d0-dddd-000000000198?type=UnderCategory2&page=0

Pesquisar : Moedas,  Moedas antigas (650 B.C. to 1453 A.C), MoedasPesquisar : Moedas, Moedas antigas (650 B.C. to 1453 A.C), Moedas

Below CLOACIN, legend: L MVSSIDIVS LONGVS Sear.... Moedas Moedas antigas (650 B.C. to 1453 A.C) Moedas romanas Republic (-280 ...
more infohttps://www.colleconline.com/pt/Search/ByPle/feae0c33-33f9-40d0-dddd-000000000198?type=UnderCategory2&page=0

Volume 140, Issue 2 | Microbiology SocietyVolume 140, Issue 2 | Microbiology Society

The results indicated a possible correlation between stability of the BRP signal peptide and cloacin DF13-release. ... the hybrid constructs were tested for their ability to promote BRP-mediated cloacin DF13-release and their ability to affect ... required for efficient release of cloacin DF13. We investigated the structural requirements for stability of the BRP signal ...
more infohttps://www.microbiologyresearch.org/content/journal/micro/140/2?pageSize=50&page=1

comitium - NumisWiki, The Collaborative Numismatics Projectcomitium - NumisWiki, The Collaborative Numismatics Project

COMITIUM.- This place of public assembly to which reference has already been made under the head of CLOACIN (see p. 219), was ...
more infohttps://www.forumancientcoins.com/numiswiki/view.asp?key=comitium

clm.的解释 - 橡木精准查词clm.的解释 - 橡木精准查词

cloacin. cloak. cloak room. cloak room ticket. cloak-and-dagger. cloak-and-suiter. cloak-and-sword. cloaking. cloakroom. ...
more infohttp://en.xmude.com/clm.---440da06e/
  • CONCORDIA, diademed and veiled bust of Concordia right, crescent below chin / L. MVSSIDIVS LONGVS, shrine of Venus Cloacina inscribed CLOACIN on which there are two statues of the goddess. (aeqvitas.com)
  • star below chin / Shrine of Venus Cloacina: Circular platform surmounted by two statues of the goddess, each resting right hand on cippus, the platform inscribed CLOACIN and ornamented with trellis-pattern balustrade, flight of steps and portico on left. (vcoins.com)