Clinical Protocols
Genetic Therapy
Neoplasms
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Magnetic Resonance Imaging
Treatment Outcome
Osteoporosis
Bone Density
The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.
Osteoporotic Fractures
Chemistry, Clinical
Bone Remodeling
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Osteoporosis, Postmenopausal
Saccades
Visual Cortex
Motor Cortex
Area of the FRONTAL LOBE concerned with primary motor control located in the dorsal PRECENTRAL GYRUS immediately anterior to the central sulcus. It is comprised of three areas: the primary motor cortex located on the anterior paracentral lobule on the medial surface of the brain; the premotor cortex located anterior to the primary motor cortex; and the supplementary motor area located on the midline surface of the hemisphere anterior to the primary motor cortex.
Photic Stimulation
Brain Mapping
Sterol Esterase
Ethical Review
A formal process of examination of patient care or research proposals for conformity with ethical standards. The review is usually conducted by an organized clinical or research ethics committee (CLINICAL ETHICS COMMITTEES or RESEARCH ETHICS COMMITTEES), sometimes by a subset of such a committee, an ad hoc group, or an individual ethicist (ETHICISTS).
Drug Industry
Ethics Committees, Research
Hypopituitarism
Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.
Androstenols
Newspapers
Bone Density Conservation Agents
A multicomponent intervention to prevent delirium in hospitalized older patients. (1/2588)
BACKGROUND: Since in hospitalized older patients delirium is associated with poor outcomes, we evaluated the effectiveness of a multicomponent strategy for the prevention of delirium. METHODS: We studied 852 patients 70 years of age or older who had been admitted to the general-medicine service at a teaching hospital. Patients from one intervention unit and two usual-care units were enrolled by means of a prospective matching strategy. The intervention consisted of standardized protocols for the management of six risk factors for delirium: cognitive impairment, sleep deprivation, immobility, visual impairment, hearing impairment, and dehydration. Delirium, the primary outcome, was assessed daily until discharge. RESULTS: Delirium developed in 9.9 percent of the intervention group as compared with 15.0 percent of the usual-care group, (matched odds ratio, 0.60; 95 percent confidence interval, 0.39 to 0.92). The total number of days with delirium (105 vs. 161, P=0.02) and the total number of episodes (62 vs. 90, P=0.03) were significantly lower in the intervention group. However, the severity of delirium and recurrence rates were not significantly different. The overall rate of adherence to the intervention was 87 percent, and the total number of targeted risk factors per patient was significantly reduced. Intervention was associated with significant improvement in the degree of cognitive impairment among patients with cognitive impairment at admission and a reduction in the rate of use of sleep medications among all patients. Among the other risk factors per patient there were trends toward improvement in immobility, visual impairment, and hearing impairment. CONCLUSIONS: The risk-factor intervention strategy that we studied resulted in significant reductions in the number and duration of episodes of delirium in hospitalized older patients. The intervention had no significant effect on the severity of delirium or on recurrence rates; this finding suggests that primary prevention of delirium is probably the most effective treatment strategy. (+info)Can we cure indolent lymphomas? (2/2588)
The current consensus is that indolent lymphomas are incurable disorders. There are some indications that these malignancies are potentially curable. Indeed, not all indolent lymphomas are currently incurable. For example, patients with Ann Arbor stage I-II indolent lymphomas can experience long-term disease-free survival and probable cure. Also, from the available literature data, it seems that the achievement of a molecular complete remission is a desirable objective. Patients who achieve a persistently negative PCR state seldom relapse, whereas the opposite is true for persistently positive cases. In view of its excellent correlation with disease-free survival when examined serially in multiple blood or marrow samples, the PCR technique has the potential of providing a tumor marker that can be used as an early end point for clinical trials. By serving as an early surrogate end point, PCR could play an important role in expediting the development of new treatment strategies. Whether IFN is capable of increasing the molecular complete remission rate as measured by PCR is not known. However, it is clear that from the clinical standpoint, IFN has been able to increase 2-fold the length of remission in patients with advanced indolent lymphomas. In at least two studies, this has been associated with prolongation of survival. More intensive regimens such as alternating triple therapy, when used in combination with IFN, seem to have improved the quality of remissions as judged by the PCR assay. Finally, the site where the bcl-2 breakpoint occurs seems to have clinical significance. Those follicular lymphomas with germ-line bcl-2, in our experience, have behaved more aggressively than the others, and their failure-free survival seems different from the usual indolent lymphomas and more closely resembles the large cell lymphomas. Although the biological significance of this observation is not yet understood, this group might actually constitute a prognostically different subset with a more aggressive and perhaps more curable lymphoma. Whether the plateau observed in their failure-free survival curve will be maintained with more follow-up and whether they might be a curable subset remain to be determined. (+info)Low-molecular-weight heparin in outpatient treatment of DVT. (3/2588)
Patients with a diagnosis of acute deep venous thrombosis have traditionally been hospitalized and treated with unfractionated heparin followed by oral anticoagulation therapy. Several clinical trials have shown that low-molecular-weight heparin is at least as safe and effective as unfractionated heparin in the treatment of uncomplicated deep venous thrombosis. The use of low-molecular-weight heparin in an outpatient program for the management of deep venous thrombosis provides a treatment alternative to hospitalization in selected patients. Use of low-molecular-weight heparin on an outpatient basis requires coordination of care, laboratory monitoring, and patient education and participation in treatment. Overlapping the initiation of warfarin permits long-term anticoagulation. Advantages include a decreased incidence of heparin-induced thrombocytopenia and fewer episodes of bleeding complications. Future clinical trials evaluating the safety and efficacy of low-molecular-weight heparin in the treatment of complicated deep venous thrombosis will further define appropriate indications for use and strategies for outpatient management. (+info)Time course of respiratory decompensation in chronic obstructive pulmonary disease: a prospective, double-blind study of peak flow changes prior to emergency department visits. (4/2588)
The aim of this study was to look at changes in peak expiratory flow rates (PEFR) prior to emergency department visits for decompensated chronic obstructive pulmonary disease (COPD). It was designed as a prospective, double-blind study at the Albuquerque Veterans Affairs Medical Center. Twelve patients with an irreversible component of airflow obstruction on pulmonary function tests were assessed. At entry, all subjects were instructed in the use of a mini-Wright peak flow meter with electronic data storage. They then entered a 6-month monitoring phase in which they recorded PEFR twice daily, before and after bronchodilators. The meter displays were disabled so that the patients and their physicians were blinded to all values. Medical care was provided in the customary manner. Patients were considered to have respiratory decompensation if they required treatment for airflow obstruction in the Emergency Department (ED) and no other causes of dyspnea could be identified. Simple linear regression was used to model changes in PEFR over time. The 12 subjects had 22 episodes of respiratory decompensation during 1741 patient-days of observation. Two episodes could not be analysed because of missing values. Ten episodes in seven subjects were characterized by a significant linear decline in at least one peak flow parameter prior to presentation. The mean rates of change for the four daily parameters varied from 0.22% to 0.27% predicted per day (or 1.19 to 1.44 1 min-1 day-1). The average decrement in these parameters ranged from 30.0 to 33.8 1 min-1 (or 18.6%-25.9% of their baseline values). No temporal trends were found for the 10 episodes occurring in the other five subjects. We concluded that respiratory decompensation is characterized by a gradual decline in PEFR in about half of cases. Future studies should be done to elucidate the mechanisms of respiratory distress in the other cases. (+info)Enhancing the identification of excessive drinkers on medical wards: a 1-year follow-up study. (5/2588)
This paper describes a 1-year follow-up study examining whether hospital ward doctors and nurses continue to take quantitative alcohol histories and provide brief intervention to problem drinkers on general medical wards after the introduction of a simple protocol. Regular training in the use of this protocol was stipulated in the annual service contract between the Health Authority and the Hospital Trusts. Improvements in staff practice persisted at 1-year follow-up, although it fell from a peak at an earlier phase of the study. The positive role of state purchasers of health services in sustaining improvements in clinical practice is discussed. (+info)Agreeing criteria for audit of the management of induced abortion: an approach by national consensus survey. (6/2588)
OBJECTIVE: To obtain a national consensus view of suggested criteria for good quality care in induced abortion to serve as a basis for standards for audit to assess current clinical practice. DESIGN: Postal, questionnaire survey assessing consensus agreement with criteria identified from a literature review and refined by an invited panel of four gynaecologists and the gynaecology audit project in Scotland (GAPS) committee. SETTING: Scotland. SUBJECTS: All 132 practising consultant gynaecologists. MAIN MEASURES: Overall level of agreement with each of 20 suggested audit criteria. RESULTS: 121 completed questionnaires were received (response rate 92%), of which 119 were returned in time for analysis; 107 came from consultants who practised abortion routinely and were included in the analysis. Nineteen of 20 suggested criteria were validated by an overall balance of agreement. The most strongly supported criterion (agreement score +93) was for ascertaining rhesus status of the woman and prophylaxis after abortion, if indicated. The only criterion to elicit a negative agreement score (-27) was that dilatation and evacuation is the best method of abortion at 12-15 weeks' gestation. The ranked and prioritised criteria resulting from this exercise are being used within a national audit project. CONCLUSIONS: A postal questionnaire survey among interested clinicians resulted in a good response rate and enabled the audit criteria to be validated and ranked more objectively and among more clinicians, than would have been possible by group discussion. (+info)Audit of thrombolysis initiated in an accident and emergency department. (7/2588)
Early thrombolytic therapy after acute myocardial infarction is important in reducing mortality. To evaluate a system for reducing in-hospital delays to thrombolysis pain to needle and door to needle times to thrombolysis were audited in a major accident and emergency (A and E) department of a district general hospital and its coronary care unit (CCU), situated about 5 km away. Baseline performance over six months was assessed retrospectively from notes of 43 consecutive patients (group 1) transferred to the CCU before receiving thrombolysis. Subsequently, selected patients (23) were allowed to receive thrombolysis in the A and E department before transfer to the CCU. The agent was administered by medical staff in the department after receiving oral confirmation of myocardial infarction from the admitting medical officer in the CCU on receipt of fax transmission of the electrocardiogram. A second prospective audit during six months from the start of the new procedure established time intervals in 23 patients eligible to receive thrombolysis in the A and E department (group 2b) and 30 ineligible patients who received thrombolysis in the CCU (group 2a). The groups did not differ significantly in case mix, pre-hospital delay, or transfer time to the CCU. In group 2b door to needle time and pain to needle time were reduced significantly (geometric mean 38 min v 121 min (group 2a) and 128 min (group 1); 141 min v 237 min (group 2a) and 242 min (group 1) respectively, both p < 0.0001). The incidence of adverse effects was not significantly different. Nine deaths occurred (six in group 1, three in group 2b), an in-hospital mortality of 9.9%. Thrombolysis can be safely instituted in the A and E department in selected patients, significantly reducing delay to treatment. (+info)Improving quality through cost recovery in Niger. (8/2588)
New evidence on the quality of health care from public services in Niger is discussed in terms of the relationships between quality, costs, cost-effectiveness and financing. Although structural attributes of quality appeared to improve with the pilot project in Niger, significant gaps in the implementation of diagnostic and treatment protocols were observed, particularly in monitoring vital signs, diagnostic examination and provider-patient communications. Quality improvements required significant investments in both fixed and variable costs; however, many of these costs were basic input requirements for operation. It is likely that optimal cost-effectiveness of services was not achieved because of the noted deficiencies in quality. In the test district of Boboye, the revenues from the copayments alone covered about 34% of the costs of medicines or about 20% of costs of drugs and administration. In Say, user fees covered about 50-55% of the costs of medicines or 35-40% of the amount spent on medicines and cost-recovery administration. In Boboye, taxes plus the additional copayments covered 120-180% of the cost of medicines, or 75-105% of the cost of medicines plus administration of cost recovery. Decentralized management and legal conditions in the pilot districts appeared to provide the necessary structure to ensure that the revenues and taxes collected would be channelled to pay for quality improvements. (+info)
SYSTEMS AND METHODS FOR CLINICAL PROTOCOL DEVELOPMENT - Patent application
A method for discovering and inferring appropriate eligibility criteria in clinical trial protocols without labeled data | BMC...
Clinical Protocols in Obstetrics and Gynecology, 3rd Edition - ایران تکست بوک
ABM clinical protocol #1: guidelines for blood glucose monitoring and treatment of hypoglycemia in term and late-preterm...
Digging into the Moderna Vaccine Clinical Trials Protocols and Results | Richard Jaffe, Esq.
Three approaches to glucose monitoring in non-insulin treated diabetes: a pragmatic randomized clinical trial protocol | BMC...
Use of an accelerated chest pain assessment protocol in patients at intermediate risk of adverse cardiac events | The Medical...
Abdominal Exam IV: Acute Abdominal Pain Assessment | Protocol (Translated to German)
Rapid Health Assessment Protocols for Emergencies - 1 - Preparedness
Protocol Development and Regulatory Support
WHO/Europe |
2013 Revision - Protocol 4. Management of tuberculosis and HIV coinfection
At a Glance - Updated CME INDIA COVID Management Protocol 2021 - CME INDIA
All recomendations
Best Practices in Evaluating Novel Biomarker Fit for Purpose and Translatability<...
Provision of services for the treatment of bronchial asthma
Evidence-based Implant Treatment Planning and Clinical Protocols PDF - Am-Medicine
CCCTG - Standard Operating Procedures Clinical Protocol Ie: Cerebrospinal Fluid Sample Collection - PLATELET
CORRECTING and REPLACING -- Celsion Files Immunotherapy Clinical Protocol for the Evaluation of GEN-1 to Treat Newly Diagnosed...
Essentials of Clinical Research | Department of Epidemiology & Population Health | Stanford Medicine
286390876 Profile
| BrightOwl
Strategic Feasibility Research Analyst I (Office-Based) - IQVIA Biotech - IQVIA | Morrisville, NC
Categories
Plus it
Electronic meal ordering systems - Sax Institute - Sax Institute
Lori Goldman, LAC | Counselor / Therapist in Princeton Junction, NJ 08550
Denine Hasan, LPC | Licensed Professional Counselor in Freehold, NJ 07728
Datasets - TRCA Open Data
EFSA Journal | Autorité européenne de sécurité des aliments
EFSA Journal | Autorité européenne de sécurité des aliments
Child of Trans Labs | ICTR
Plus it
Treatment Protocols | Million Hearts®
Http11AprProtocol (Apache Tomcat 8.5.59 API Documentation)
AjpAprProtocol (Apache Tomcat 7.0.106 API Documentation)
SP 800-52 Rev. 2, Guidelines for TLS Implementations | CSRC
Ivermectin not to be included in Centres coronavirus management protocol - india news - Hindustan Times
Difference between revisions of EBQ:ProCESS Trial - WikEM
IJERPH | Free Full-Text | Measuring Quality Gaps in TB Screening in South Africa Using Standardised Patient Analysis | HTML
help! | allnurses
RTMP White Papers - Bitpipe
New protocols - ANONYMOUS-ASTHMA
Protocol 1000 - MMS Wiki | Jim Humble | Genesis 2 Church | MMSWiKi.is
Kubke Lab:Protocols - OpenWetWare
The Dulce Protocol by Robert Teske - Free PDF - Page 15
S-(2-thiopyridyl)mercaptopropionohydrazide | Semantic Scholar
STroke imAging pRevention and treatment (START): a longitudinal stroke cohort study: clinical trials protocol
2010 - Modules, Aberystwyth University
Everything About Wood: Sampling termite assemblages in tropical forests: testing a rapid biodiversity assessment protocol
Protocol development for assays of bone and cartilage tissues from mouse tibio-femoral joints - Melbourne School of Engineering
Searching for management approaches to reduce HAI transmission (SMART): a study protocol | Implementation Science | Full Text
Protocol-Driven Primary Care and Community Linkages to Improve Population Health in Rural Zambia: the Better Health Outcomes...
Simplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia - Full Text View - ClinicalTrials.gov
Simplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia - Full Text View - ClinicalTrials.gov
Better Access to Information about Clinical Trials | Annals of Internal Medicine | American College of Physicians
Management of the infertile couple: an evidence-based protocol | Reproductive Biology and Endocrinology | Full Text
ESTABLISHMENT OF CLINICAL PROTOCOL TARGETING CANCER STEM CELLS IN RECURRENT GLIOBLASTOMA USING HIGH-THROUGHPUT DRUG SCREENING
Most recent papers with the keyword geriatric anaesthesia | Read by QxMD
PLOS Medicine: Inadequate Dissemination of Phase I Trials: A Retrospective Cohort Study
PLOS Medicine: Inadequate Dissemination of Phase I Trials: A Retrospective Cohort Study
Acute effects of reducing sitting time in adolescents: a randomized cross-over study
Prednisone 3 times a day - Prix viagra pharmacie algerie 2017
NOT REAL NEWS: A look at what didnt happen this week | Hawaii Tribune-Herald
Nivestim 12 MU/ 0.2 ml solution for injection/infusion, Nivestim 30 MU/ 0.5 ml solution for injection/infusion, Nivestim 48MU/...
Early-goal directed therapy for septic shock: is it the end? - Minerva Anestesiologica 2015 October;81(10):1138-43 - Minerva...
Diversity and Democracy | Volume 12, Number 1 | Designing a Model for International Learning Assessment
Get lean. Lose the stomach fat. Keep it off. - AYO Training Nutrition
DRKS - Deutsches Register Klinischer Studien (German Clinical Trials Register)
DRKS - Deutsches Register Klinischer Studien (German Clinical Trials Register)
Grants:Project/Browse applications - Meta
Master of Science in Translational Research
Cancer Therapy Evaluation Program (CTEP)
Potential Effect of Interfacial Bonding on Used Nuclear Fuel Vibration Reliability (Conference) | SciTech Connect
Home Page | azmedmj.org
Animal Models
Clinical Trial Phases | FDA | Eye Research | Cincinnati | Apex Eye
NIH Honors Moayeri 20 for Exceptional Biomedical Research | Harvey Mudd College News
FDA Announces New Protocol for the Development and Registration of Treatments for Preharvest Agricultural Water
New protocol to visualize gene expression in intact and regenerating adult planarians by whole mount in situ hibridization<...
Enhanced Recovery After Spine Surgery: A Systematic Review. | AAPM
Osteosarcoma Clinical Trials : Eleison Pharmaceuticals LLC
Meet the employers - University of Copenhagen
ICIM: Your Between Conference Connection
SLE: reconciling heterogeneity | Lupus Science & Medicine
What We Do - Cabernet Pharmaceuticals Inc.
Motion correction in medical imaging. - Surrey Research Insight Open Access
Methylation - Vanita Dahia
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. - ORA - Oxford...
IQ Scripts
NATO Adopts New Protocol Standard for Underwater Communications - News
Kate Tchanturia
"Clinical packages & Protocols". katetchanturia.com. "PEACE Pathway Website". peacepathway.org. Tchanturia, Kate, (2015). Brief ... Pathway for Eating disorders and Autism developed from Clinical Experience). This clinical pathway was funded by The Health ... After relocating to London in 1997, she became a clinical research fellow at the Institute of Psychiatry, King's College London ... She has developed a novel clinical pathway for patients with comorbid autism spectrum disorders and eating disorders at the ...
Canavan disease
"Clinical protocol. Gene Therapy of Canavan Disease: AAV-2 Vector for Neurosurgical Delivery of Aspartoacylase Gene (ASPA) to ...
Healthcare in Belize
Limited clinical protocols for patient management. Limited technical operational manuals for program implementation. Health ...
Breastfeeding
"ABM Clinical Protocol #11. 1 (1): 3. doi:10.1186/1746-4358-1-3. PMC 1464379. PMID 16722609.. ... Hanson LA, Söderström T (1981). "Human milk: Defense against infection". Progress in Clinical and Biological Research. 61: 147- ... Hendrickson RG, McKeown NJ (January 2012). "Is maternal opioid use hazardous to breast-fed infants?". Clinical Toxicology. 50 ( ... Haastrup MB, Pottegård A, Damkier P (February 2014). "Alcohol and breastfeeding". Basic & Clinical Pharmacology & Toxicology. ...
Intersex medical interventions
In 2006, an invited group of clinicians met in Chicago and reviewed clinical evidence and protocols, and adopted a new term for ... Alice Dreger, a US professor of Clinical Medical Humanities and Bioethics, argues that little has changed in actual clinical ... Large majorities of respondents opposed standard clinical protocols.[71] 2016 Global DSD Update[edit]. A 2016 follow-up to the ... The committee stated: "clinical intervention pathways stated to be based on probabilities of cancer risk may be encapsulating ...
Virginity test
Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... Clinical and Pathological Aspects, Greenwich Medical Media: London, a)p.453, b)p.455 c)p.460. "Muslim women in France regain ...
Virginity
Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... Clinical and Pathological Aspects, Greenwich Medical Media: London, a)p.453, b)p.455 c)p.460. The Marks of Childhood or the ... vaginal examinations for verifying a woman's virginity are a clinical practice which are at times state-enforced. These types ...
List of common misconceptions
Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... US Navy protocols discourage the practice, while the other four branches have specific regulations against it. Legal tender ... Kopelman M. D.; Thomson A.D.; Guerrini I.; Marshall E.J. (2009). "The Korsakoff syndrome: clinical aspects, psychology and ... Weisberger, L; Jamieson, B (July 2009). "Clinical inquiries: How can you help prevent a recurrence of diverticulitis?". The ...
Vagina
ISBN 978-0-7131-4452-9. Perlman SE, Nakajyma ST, Hertweck SP (2004). Clinical protocols in pediatric and adolescent gynecology ... ISBN 978-0-323-29358-7. Alldredge BK, Corelli RL, Ernst ME (2012). Koda-Kimble and Young's Applied Therapeutics: The Clinical ... ISBN 978-0-495-11308-9. Sirven JI, Malamut BL (2008). Clinical Neurology of the Older Adult. Lippincott Williams & Wilkins. pp ... ISBN 978-1-135-82509-6. Balon R, Segraves RT (2009). Clinical Manual of Sexual Disorders. American Psychiatric Pub. p. 258. ...
Hymen
Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... Clinical and Pathological Aspects, Greenwich Medical Media: London, a)p.453, b)p.455 c)p.460. Heger, Astrid; Emans, S. Jean; ... Journal of Clinical Forensic Medicine. 13 (4): 172-180. doi:10.1016/j.jcfm.2006.02.006. ISSN 1353-1131. PMID 16564196. Hymen ...
Marburg virus disease
Weidmann, M.; Mühlberger, E.; Hufert, F. T. (2004). "Rapid detection protocol for filoviruses". Journal of Clinical Virology. ... "Journal of Clinical Microbiology. 40 (7): 2323-2330. doi:10.1128/jcm.40.7.2323-2330.2002. PMC 120575 . PMID 12089242.. ... "Clinical and Vaccine Immunology. 13 (4): 444-451. doi:10.1128/CVI.13.4.444-451.2006. PMC 1459631 . PMID 16603611.. ... "Journal of Clinical Microbiology. 45 (1): 224-226. doi:10.1128/JCM.01893-06. PMC 1828965 . PMID 17079496.. ...
Inland taipan
Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. "Signs and Symptoms of Envenomation: E. Fang ... Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. "Signs and Symptoms of Envenomation: E. Fang ... Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. University of Adelaide. Retrieved October 18, ... Clinical Toxinology Resources. "Oxyuranus microlepidotus -General Details, Taxonomy and Biology, Venom, Clinical Effects, ...
History of intersex surgery
... an invited group of clinicians met in Chicago and reviewed clinical evidence and protocols, argued that and adopted a new term ... Large majorities of respondents opposed standard clinical protocols. A 2016 follow-up to the 2006 Consensus Statement, termed a ... There are no controlled clinical trials of the efficacy of early (less than 12 months of age) versus late surgery (in ... Clinical Pediatric and Adolescent Endocrinology.. Philadelphia: Saunders. An example of a now-obsolete recommendation to ...
Rapid response system
"What stops hospital clinical staff from following protocols? An analysis of the incidence and factors behind the failure of ... These tools can predict clinical deterioration based upon the patient's trait (e.g. has epilepsy) and detect deterioration ... UK National Institute for Health and Clinical Excellence (NICE) (July 2007). "Acutely ill patients in hospital: recognition of ... A RRS consists of two clinical components (afferent and efferent) and two organizational components (process improvement and ...
Flow-induced dispersion analysis
Clinical Applications of Capillary Electrophoresis: Methods and Protocols. Methods in Molecular Biology. 1972. New York, NY: ...
Retroprogesterone
ISBN 978-94-009-8195-9. Lt Col Pankaj Talwar; Surveen Ghumann Sindhu (18 May 2012). Step by Step: Protocols in Clinical ...
Investigational New Drug
Clinical trial protocols are the centerpiece of the IND. Detailed protocols for proposed clinical studies to assess whether the ... If the FDA detects a problem, it may place a clinical hold on the IND, prohibiting the start of the clinical studies until the ... Once an IND is submitted, the FDA has 30 days to object to the IND or it automatically becomes effective and clinical trials ... About half of the INDs fail in preclinical and clinical phases of drug development. The FDA runs a medical marijuana IND ...
Taipan pedalaman bahasa Indonesia, ensiklopedia bebas
Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. "Signs and Symptoms of Envenomation: E. Fang ... Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. "Signs and Symptoms of Envenomation: E. Fang ... Clinical Toxinology Resources. "Oxyuranus microlepidotus -General Details, Taxonomy and Biology, Venom, Clinical Effects, ...
母乳哺育 - 维基百科,自由的百科全书
ABM Clinical Protocol #11. (原始内容存档于2006-08-11).. ... Is maternal opioid use hazardous to breast-fed infants?. Clinical toxicology (Philadelphia, PA). 2012-01, 50 (1): 1-14. PMID ...
Agoraphobia
Wyatt, Richard Jed; Chew, Robert H. (2008). Wyatt's Practical Psychiatric Practice: Forms and Protocols for Clinical Use. ... The disappearance of residual and sub-clinical agoraphobic avoidance, and not simply of panic attacks, should be the aim of ... In the social sciences, a perceived clinical bias exists in agoraphobia research. Branches of the social sciences, especially ... Clinical Psychology Review. 30 (1): 37-50. doi:10.1016/j.cpr.2009.08.011. PMID 19775792. "Agoraphobia - Diagnosis and treatment ...
Chiropractic in Canada
This experience includes clinical assessment, diagnosis, treatment, and referral protocols. The faculty at both CMCC and UQTR ... Candidates must successfully pass Components A and B (Written Cognitive Skills Examination) to be eligible for the Clinical ... Radiology training consists of more than 360 contact hours followed by application during clinical internship. CMCC and UQTR ... Canadian Chiropractic Examining Board requires all candidates to complete a 12-month clinical intership to obtain licensure, as ...
Haloperidol decanoate
Forms and Protocols for Clinical Use. American Psychiatric Pub. pp. 142-. ISBN 978-1-58562-687-8. Katherine M. Fortinash; ... Larsson M, Axelsson R, Forsman A (1984). "On the pharmacokinetics of perphenazine: a clinical study of perphenazine enanthate ... Abstract.). 19th Annual Midyear Clinical Meeting of the American Society of Hospital Pharmacists. Dallas, Texas. Janssen PA, ... The Journal of Clinical Psychiatry. 45 (5 Pt 2): 50-9. PMID 6143748. Curry SH, Whelpton R, de Schepper PJ, Vranckx S, Schiff AA ...
Thoratec
MOMENTUM 3 IDE Clinical Study Protocol (HM3). U.S. National Institutes of Health. ClinicalTrials.gov. Retrieved September 16, ... is still in clinical trials for destination therapy. In a two-year randomized controlled clinical trial published in 2009 ... It began undergoing clinical trials in the U.S. and internationally in mid 2014. In mid 2014, CE Mark trials also started for ... It is cleared for clinical use up to six hours, and can be used as a short-term solution to support the circulation while ...
EMA401
Spinifex Pharmaceuticals Pty Limited (2011). "CLINICAL STUDY PROTOCOL: Protocol No. EMA401-003". Cite journal requires ,journal ... Spinifex Pharmaceuticals Pty Limited (2011). "CLINICAL STUDY PROTOCOL: Protocol No. EMA401-003". Cite journal requires ,journal ... Spinifex Pharmaceuticals Pty Limited (2011). "CLINICAL STUDY PROTOCOL: Protocol No. EMA401-003". Cite journal requires ,journal ... Phase I clinical trial have indicated that doses of EMA401 up to 400 mg are safe in humans. Spinifex Pharmaceuticals reported ...
Moderna COVID-19 vaccine
"Clinical Study Protocol mRNA-1273-P301" (PDF). Moderna. COVID-19 Vaccine Moderna assessment report European Medicines Agency " ... The clinical trial is ongoing and is set to conclude in late 2022. In November 2020, Nature reported that "While it's possible ... A review by the FDA in December 2020, of interim results of the Phase III clinical trial on mRNA-1273 showed it to be safe and ... The vaccine in low doses was deemed safe and effective in order to advance a Phase III clinical trial using two 100-μg doses ...
Variant of uncertain significance
Burke W (April 2014). "Genetic tests: clinical validity and clinical utility". Current Protocols in Human Genetics. 81: 9.15.1- ... The term "variant' is favored in clinical practice over "mutation" because it can be used to describe an allele more precisely ... March 2020). "How Can Law and Policy Advance Quality in Genomic Analysis and Interpretation for Clinical Care?". The Journal of ... As of 2020[update], there continues to be limited involvement from federal agencies to regulate the clinical validity (accuracy ...
Pure tone audiometry
Bagatto, M; Moodie, S; Scollie, S; Seewald, R; Moodie, S; Pumford, J; Liu, KP (2005). "Clinical protocols for hearing ... As with most clinical tests, standardized calibration of the test environment, the equipment and the stimuli is needed before ... Although pure-tone audiometry has many clinical benefits, it is not perfect at identifying all losses, such as 'dead regions' ... Handbook of clinical audiology. Katz, Jack., Burkard, Robert, 1953-, Medwetsky, Larry. (5th ed.). Philadelphia: Lippincott ...
William French Anderson
The clinical protocol began on May 22, 1989, and included 10 patients. The procedure was shown to be safe. Rosenberg went on to ... Only after approval by that formal public governmental review did the gene therapy clinical protocol move on for review by the ... Microinjecting a few non-stem cells was clearly not an efficient procedure for a clinical protocol. In 1984, Anderson published ... Anderson, together with bioethicist John Fletcher, set the ethical standard for this type of clinical protocol in his 1980 ...
Forensic biology
Postmortem microbiology in sudden death: sampling protocols proposed in different clinical settings. Clinical Microbiology and ... Forensic toxicology is the use of toxicology and other disciplines such as analytical chemistry, pharmacology and clinical ...
Alternative medicine
"British Journal of Clinical Pharmacology. 54 (6): 577-82. doi:10.1046/j.1365-2125.2002.01699.x. PMC 1874503. PMID 12492603.. ... Research into alternative therapies often fails to follow proper research protocols (such as placebo-controlled trials, blind ... clinical statisticians and pharmacologists, use clinical trials to reveal such effects, allowing physicians to offer a ... "British Medical Journal (Clinical Research Ed.). 287 (6388): 307-08. doi:10.1136/bmj.287.6388.307. PMC 1548588. PMID 6307462. ...
Quantitative trait locus
"Clinical Genetics: A Self-Study Guide for Health Care Providers. University of South Dakota School of Medicine. Archived from ... Methods and Protocols, Methods in Molecular Biology, Springer US, 2072, pp. 15-25, doi:10.1007/978-1-4939-9865-4_3, ISBN ... Methods and Protocols, Methods in Molecular Biology, Springer US, pp. 15-25, doi:10.1007/978-1-4939-9865-4_3, ISBN ...
Saint Barnabas Medical Center
Free clinical education programs are prehospital care, emergency department & hospital programs, and nursing school program. ... and embryo selection protocols. The research achievements from the Institute received both praise and criticism. The works have ...
Acne
Archer CB, Cohen SN, Baron SE (May 2012). "Guidance on the diagnosis and clinical management of acne". Clinical and ... This scale was the first to use a standardized photographic protocol to assess acne severity; since its creation in 1979, the ... Marchetti PM, Barth JH (March 2013). "Clinical biochemistry of dihydrotestosterone". Annals of Clinical Biochemistry. 50 (Pt 2 ... Brandt S (May 2013). "The clinical effects of zinc as a topical or oral agent on the clinical response and pathophysiologic ...
Hematopoietic stem cell transplantation
Clinical observations[edit]. A study involving 2408 donors (18-60 years) indicated that bone pain (primarily back and hips) as ... 2008). "Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases". JAMA. 299 (8): 925-36 ... Clinical and Experimental Rheumatology. 34 (4 Suppl 98): 53-57. ISSN 0392-856X. PMID 27586805.. ... hepatomegaly and fluid retention are clinical hallmarks of this condition. There is now a greater appreciation of the ...
Medicine
Clinical laboratory sciences are the clinical diagnostic services that apply laboratory techniques to diagnosis and management ... which allows as much of the available evidence as possible to be collected and analyzed according to standard protocols that ... Subspecialties include transfusion medicine, cellular pathology, clinical chemistry, hematology, clinical microbiology and ... Some related clinical specialties include neurology, neurosurgery and psychiatry.. *Nutrition science (theoretical focus) and ...
Cervical cerclage
... should be used only in the context of a clinical trial or research protocol. While cerclage is generally a safe procedure, ... However, large randomized clinical trials in singleton and twin pregnancies found that the cervical pessary did not result in a ... "The role of cervical pessary placement to prevent preterm birth in clinical practice". American Journal of Obstetrics and ...
Genetically modified tomato
Clinical trials have been conducted on mice using tomatoes expressing antibodies or proteins that stimulate antibody production ... from which to create juice to test in clinical trials on the way to obtaining regulatory approval.[37][38] ...
Smoking ban
"Progress in Clinical and Biological Research. 337 (7070): 301-7. doi:10.1136/bmj.313.7070.1450. PMC 2352989. PMID 8973234.. ... "Treatment protocols of the lupus nephritis collaborative study of plasmapheresis in severe lupus nephritis. The Lupus ...
Lyme disease
"European Journal of Clinical Chemistry and Clinical Biochemistry (Submitted manuscript). 32 (9): 685-9. doi:10.1515/cclm. ... A two-tiered protocol is recommended by the Centers for Disease Control and Prevention (CDC): the sensitive ELISA test is ... Stanek G, Reiter M (April 2011). "The expanding Lyme Borrelia complex--clinical significance of genomic species?". Clinical ... clinical practice guidelines by the Infectious Diseases Society of America". Clinical Infectious Diseases. 43 (9): 1089-134. ...
Chiropractic
"International Journal of Clinical Practice. 66 (10): 940-47. doi:10.1111/j.1742-1241.2012.03004.x. PMC 3506737 . PMID 22994328. ... which relies on a drop table and detailed procedural protocols), Gonstead (which emphasizes evaluating the spine along with ... "Int J Clinical Practice. 64 (8): 1162-65. doi:10.1111/j.1742-1241.2010.02352.x. PMID 20642715.. ... Numerous controlled clinical studies of treatments used by chiropractors have been conducted, with conflicting results.[4] ...
Radiography
The first use of X-rays under clinical conditions was by John Hall-Edwards in Birmingham, England on 11 January 1896, when he ... "Radiation Doses of Various CT Protocols: a Multicenter Longitudinal Observation Study". Journal of Korean Medical Science. 31 ... "The first clinical X-ray made in America--100 years" (PDF). American Journal of Roentgenology. American Roentgen Ray Society. ... "A clinical audit of anatomical side marker use in a paediatric medical imaging department". Journal of Medical Radiation ...
Activated carbon
Clinical Chemistry and Laboratory Medicine. 57 (5): 690-696. doi:10.1515/cclm-2018-0967. PMID 30427777.. ... as mobile phase in analytical or preparative protocols. ...
Fluorescence in situ hybridization
FISH is often used in clinical studies. If a patient is infected with a suspected pathogen, bacteria, from the patient's ... Fibre FISH protocol from the Human Genome Project at the Sanger Centre ... Hybrid Fusion FISH enables highly multiplexed FISH applications that are targeted within clinical oncology panels. The ... and clinical relevance". Fertility and Sterility. 93 (6): 1892-902. doi:10.1016/j.fertnstert.2008.12.139. PMID 19254793.. ...
ادرار کردن - ویکیپدیا، دانشنامهٔ آزاد
Clinical conditions. Many clinical conditions can cause disturbances to normal urination, including:. *Urinary incontinence, ... Steven R. Lindsay (9 January 2008). Handbook of Applied Dog Behavior and Training, Procedures and Protocols. John Wiley & Sons ...
Coomassie Brilliant Blue
Wittig, I.; Braun, H. P.; Schägger, H. (2006). "Blue native PAGE". Nature Protocols. 1 (1): 418-428. doi:10.1038/nprot.2006.62 ... clinical relevance and in vitro analysis of the function of the outer blood-retinal barrier". Developments in Ophthalmology. ... Pink, M.; Verma, N.; Rettenmeier, A. W.; Schmitz-Spanke, S. (2010). "CBB staining protocol with higher sensitivity and mass ...
Endospore
Marise A. Hussey, Anne Zayaitz Endospore Stain Protocol Microbe Library (American Society of Microbiology) ... Murray, Patrick R.; Ellen Jo Baron (2003). Manual of Clinical Microbiology. 1. Washington, D.C.: ASM.. .mw-parser-output cite. ...
Nerve agent - Simple English Wikipedia, the free encyclopedia
"Soman and sarin: clinical manifestations and treatment of accidental poisoning by organophosphates". Clinical Toxicology 7 (1 ... "1925 Geneva Protocol". United Nations Office for Disarmament Affairs. United Natios. Retrieved February 9, 2016.. ... Geneva Protocol of 1925: This agreement was signed on June 17, 1925, and took effect on February 8, 1928. It permanently bans ... The protocol was extended by the Biological Weapons Convention (1972) and the Chemical Weapons Convention (1993). ...
Bioinformática, a enciclopedia libre
"Journal of Clinical Pathology 50 (5). Páxs. 365-370.. *↑ Craiem, D.; et al. (2008). "New Assessment of Endothelium-Dependent ... 2007). Current Protocols in Bioinformatics (en inglés). Wiley. ISBN 0-471-25093-7.. ... Transmission Control Protocol, Protocolo de control de transmisión) feito por Vinton Cerf e Robert Kahn (1974), un dos ... "Origins of... Image analysis in clinical pathology" ...
Juris Doctor
"Protocol School of Washington.. *^ "Summaries of Informal Opinions of the Standing Committee on Professional Ethics". American ... implementing elements such as clinical training, which has become an essential part of legal education in the U.S. and in the J ...
Bioarchaeology
Such markers are often based on single cases described in clinical literature in the late nineteenth century. One such marker ... "Evaluating the efficiency of different recording protocols for entheseal changes in regards to expressing activity patterns ...
Good clinical practice
High standards are required in terms of comprehensive documentation for the clinical protocol, record keeping, training, and ... The National Institutes of Health requires NIH-funded clinical investigators and clinical trial staff who are involved in the ... The Medicines for Human Use (Clinical Trials) Regulations 2004. *The Medicines for Human Use (Clinical Trials) Amendment ... clinical trial sponsors, and monitors. In the pharmaceutical industry monitors are often called clinical research associates. ...
Health professional
These include psychiatrists, psychiatry physician assistants, clinical psychologists, occupational therapists, clinical social ... It is not the intention of this article to explore the protocol of carrying out a proper TB test. A TB blood test for baseline ... These include physiatrists, physician assistants, rehabilitation nurses, clinical nurse specialists, nurse practitioners, ... They include geriatricians, occupational therapists, physician assistants, adult-gerontology nurse practitioners, clinical ...
Hand transplantation
... is one of only two programs in the United States approved to perform hand/arm transplants using an immunomodulatory protocol, ... group had performed extensive basic science research and feasibility studies for many years prior to their first clinical ...
Cold Spring Harbor Laboratory
... develop a new clinical cancer research unit at Northwell Health in Lake Success, NY, to support early-phase clinical studies of ... laboratory manuals and protocols, and online services for research preprints.[6] ... "ISIS initiates Phase 3 clinical trials for potential SMA therapy ISIS-SMNrx". The SMA Trust.. ...
Aktinium bahasa Indonesia, ensiklopedia bebas
Russell, Pamela J.; Jackson, Paul; Kingsley, Elizabeth Anne (2003), Prostate cancer methods and protocols, Humana Press, hlm. ... Clinical Cancer Research. 10 (13): 4489-97. doi:10.1158/1078-0432.CCR-03-0800 . PMID 15240541.. ...
Fluorescein
"Bio-Protocol. 8 (7): e2791. doi:10.21769/bioprotoc.2791.. *^ "The diagnosis and management of anaphylaxis. Joint Task Force on ... The Journal of Allergy and Clinical Immunology. 101 (6 Pt 2): S465-528. 1998. doi:10.1016/S0091-6749(18)30566-9. PMID 9673591. ...
Cerebral hypoxia
a b Richmond, T. S. (May 1997). "Cerebral Resuscitation after Global Brain Ischemia", AACN Clinical Issues 8 (2). Retrieved on ... "The Maryland Medical Protocols for Emergency Medical Services Providers" (PDF).. (1.00 MiB). Maryland Institute for Emergency ... The severity of a neonatal hypoxic-ischaemic brain injury may be assessed using Sarnat staging, which is based on clinical ... Focal cerebral ischemia constitutes a large majority of the clinical cases in stroke pathology with the infarct usually ...
ଜଳାତଙ୍କ - ଉଇକିପିଡ଼ିଆ
Pawan JL (1959). "Rabies in the vampire bat of Trinidad, with special reference to the clinical course and the latency of ... "Milwaukee protocol") କୁହାଗଲା । ଏହି ହାଇପୋଥେସିସ୍ ଅନୁସାରେ ଜଳାତଙ୍କ ଭୁତାଣୁର ମସ୍ତିଷ୍କ ଉପରେ ସ୍ୱଳ୍ପ କାଳୀନ ନଷ୍ଟକାରୀ ପ୍ରଭାବ ରହେ । ଏଣୁ ...
Lactose intolerance
Clinical symptoms typically appear within 30 minutes, but may take up to two hours, depending on other foods and activities.[35 ... The procedure consists of extracting and amplifying DNA from the sample, following with a hybridation protocol in a strip. ... Vandenplas Y (2015). "Lactose intolerance". Asia Pacific Journal of Clinical Nutrition (Review). 24 Suppl 1 (S1): S9-13. doi: ... Lawson M, Bentley D, Lifschitz C (2002). Pediatric gastroenterology and clinical nutrition. London: Remedica. p. 109. ISBN 978- ...
Pre-Clinical Models - Techniques and Protocols | Paul C. Guest | Springer
This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models ... Pre-Clinical Models. Book Subtitle. Techniques and Protocols. Editors. * Paul C. Guest ... Authoritative and cutting-edge, Pre-Clinical Models: Techniques and Protocols aims to provide methods that describe the context ... This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models ...
Standardised Protocols Would Greatly Enhance Clinical And Research Potential Of BTMs - Redorbit
Standardised Protocols Would Greatly Enhance Clinical And Research Potential Of BTMs. by Sam Savage ... He also noted that standardised protocols would greatly increase the clinical and research potential of BTMs, with improved ... In clinical practice, BTMs are used to monitor osteoporosis treatment. BTMs generally show large and rapid responses to the ... IOF and IFCC experts recommend international reference standards for use of bone turnover markers in clinical studies ...
Protocols and Order Sets | American Association of Clinical Endocrinologists
Posting of these protocols does not constitute endorsement of any specific protocol. We believe that each institution should ... Key Points Successful implementation of protocols requires: Buy-in from key stakeholders (critical care physicians, house staff ... consult with diabetes experts to select and implement insulin protocols. ... AACE Clinical Case Reports *Endocrine Practice - Journal *EmPower Magazine - For Patients *Advertising Opportunities *Clinical ...
Clinical Rescue Protocol - 2 - Full Text View - ClinicalTrials.gov
Clinical Rescue Protocol - 2. The safety and scientific validity of this study is the responsibility of the study sponsor and ... Treatment effectiveness score as an outcome measure in clinical trials. NIDA Res Monogr. 1997;175:208-20. Review. ... and to determine if blood levels of methadone or buprenorphine correlate with clinical response. ...
Clinical Trials Protocol Template | grants.nih.gov
Home » Policy & Compliance » Clinical Trials » Clinical Trials Protocol Template. Clinical Trials Protocol Template. Applicants ... the NIH and FDA collaboratively developed a Phase 2/3 Clinical Trial Protocol Template and an electronic protocol-writing tool ... To facilitate the development of clinical trial protocols that require a Food and Drug Administration (FDA) Investigational New ... NIH and FDA Release Protocol Template for Phase 2 and 3 IND/IDE Clinical Trials ...
AG Mednet Announces First Clinical Trial Quality Control Software for QIBA Imaging Protocol Compliance
PRNewswire/ -- Clinical trial sponsors working to standardize the capture and submission of complex imaging data through new ... AG Mednet Announces First Clinical Trial Quality Control Software for QIBA Imaging Protocol Compliance ... to the ever increasing costs and delays of clinical trials. AG Mednets SQC software for QIBA protocols removes the manual ... imaging core labs and clinical research organizations managing clinical trials globally. More than 25,000 registered users ...
Screening for LID Clinical Studies Unit Healthy Volunteer Protocols - Full Text View - ClinicalTrials.gov
Screening for LID Clinical Studies Unit Healthy Volunteer Protocols. The safety and scientific validity of this study is the ... To accomplish this objective, up to 5000 participants will be enrolled in this protocol at the NIH Clinical Center clinic or ... The Laboratory of Infectious Diseases (LID) Clinical Studies Unit (CSU) enrolls healthy volunteers into clinical studies to ... NIH Clinical Center Detailed Web Page Publications: Anderson MJ, Heath RB. Cell mediated immunity in experimental influenza and ...
LINX Reflux Management System Clinical Study Protocol - Study Results - ClinicalTrials.gov
LINX Reflux Management System Clinical Study Protocol. The safety and scientific validity of this study is the responsibility ... Includes whether analysis was per protocol, intention to treat, or another method. Also provides relevant details such as ... Includes whether analysis was per protocol, intention to treat, or another method. Also provides relevant details such as ...
Frontiers | Editorial: Tumor-Derived Extracellular Vesicles: Protocols, Models, and Clinical Evidence | Oncology
... new instruments and their related protocols enable the discovery or the improved characterization of bio-objects including ... nanovesicles within the 70-150nm diameter range that have recently aroused a great interest in the scientific and clinical ... Editorial: Tumor-Derived Extracellular Vesicles: Protocols, Models, and Clinical Evidence. Renaud Seigneuric1,2* and Carmen ... Tumor-Derived Extracellular Vesicles: Protocols, Models, and Clinical Evidence. The current frontiers in Oncology are at the ...
Developing and implementing computerized protocols for standardization of clinical decisions
... limitation and the availability of extensive information contributes to the varying performance and high error rate of clinical ... Protocols need not be perfect. Several defensible and reasonable approaches are available for clinical problems. However, one ... Developing and implementing computerized protocols for standardization of clinical decisions Ann Intern Med. 2000 Mar 7;132(5): ... including use of the protocols themselves. Computerized protocols for mechanical ventilation and management of intravenous ...
New clinical protocol after general surgery cuts opioid prescribing in half | EurekAlert! Science News
... a team of researchers at Lawson Health Research Institute and Western University have developed a new clinical protocol called ... New clinical protocol after general surgery cuts opioid prescribing in half. Lawson Health Research Institute ... A study demonstrating the efficacy of their protocol is being presented at the American College of Surgeons Clinical Congress ... a team of researchers at Lawson Health Research Institute and Western University have developed a new clinical protocol called ...
WHO/Europe | Ukraine develops modern and progressive clinical protocol for HIV treatment
WHO finalized an international review of a breakthrough clinical protocol for HIV infection in Ukraine that will put the ... Health topics Communicable diseases HIV/AIDS Ukraine develops modern and progressive clinical protocol for HIV treatment ... Ukraine develops modern and progressive clinical protocol for HIV treatment 13-12-2017. WHO finalized an international review ... of a breakthrough clinical protocol for HIV infection in Ukraine that will put the country on the fast track to scaling up HIV ...
Pre-Action Protocol for the Resolution of Clinical Disputes
... ... 2.3 This Protocol does not-. (a) provide any detailed guidance to healthcare providers on clinical risk management or the ... Enforcement of the Protocol and sanctions. 1.7 Where either party fails to comply with this Protocol, the court may impose ... b) the Pre-Action Protocol for Personal Injury Claims;. (c) the Pre-Action Protocol for Low Value Personal Injury Claims in ...
Modeling Clinical Protocols Using Semantic MediaWiki: The Case of the Oncocure Project | SpringerLink
... can improve the adherence of the clinicians to clinical guidelines and protocols. The building of a prescriptive DSS based on ... Eccher C., Ferro A., Seyfang A., Rospocher M., Miksch S. (2009) Modeling Clinical Protocols Using Semantic MediaWiki: The Case ... A computerized Decision Support Systems (DSS) can improve the adherence of the clinicians to clinical guidelines and protocols ... Modeling Clinical Protocols Using Semantic MediaWiki: The Case of the Oncocure Project. ...
SPIRIT 2013 statement: defining standard protocol items for clinical trials
However, trial protocols and existing protocol guidelines vary greatly in content and quality. This article describes the ... The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting, and appraisal. ... systematic development and scope of SPIRIT (Standard Protocol Ite … ... for the minimum content of a clinical trial protocol.The 33-item SPIRIT checklist applies to protocols for all clinical trials ...
Paradigms for Clinical fMRI - Current Protocols
This unit presents description of four basic clinical paradigms for clinical fMRI of language cmprehension, eye movement ( ... This unit presents description of four basic clinical paradigms for clinical fMRI of language cmprehension, eye movement ( ... Comprehensive MRI protocol for stroke management: Tissue sodium concentration as a measure of tissue viability in a non‐human ... primate model and clinical studies. Radiology 139:26‐34. Thulborn, K.R., Martin, C., and Voyvodic, J. 2000. fMRI using a ...
Protocols/Clinical Trials - AIDS Clinical Trials Group - Research - Infectious Disease - Medicine - University of Rochester...
Evidence-Based Clinical Chelation: A Textbook with Protocols for the ... - Dr. Eleonore Blaurock-Busch, PhD, Dr. Swaran J.S....
It contains specific protocols for the treatment of chronic metal overexposure, all of which are evidence-based, aiding the ... All the protocols listed have been modified for the treatment of chronic metal intoxication, included are oral and intravenous ... The authors explain in simple terms how a chelating agent ́s bioavailability affects metal binding and how various protocols ... such as the Cutler Protocol affect the detoxification process, why DMPS binds mercury and which chelators are useful for the ...
Pfizer and Astellas Amend Clinical Research Protocols for Two Phase 3 Trials of Enzalutamide in Patients with Hormone-Sensitive...
... including unfavorable new clinical data and additional analyses of existing clinical data; the risk that clinical trial data ... Pfizer and Astellas Amend Clinical Research Protocols for Two Phase 3 Trials of Enzalutamide in Patients with Hormone-Sensitive ... amendments to protocols of the ARCHES and EMBARK clinical trials and the expected primary completion dates of those trials, ... Our goal is to build upon the body of clinical evidence for enzalutamide in an effort to help address the unmet needs of an ...
Advances in Audiology and Hearing Science: Volume 1: Clinical Protocols and Hearing Devices, 1st Edition (Hardback) - Routledge
Part 1: Clinical Protocols Revised. 1. Current and Emerging Clinical Applications of the Auditory Steady-State Response (ASSR) ... Volume 1 primarily focuses on revised clinical protocols and provides information on new research to help guide decisions and ... 9. Clinical Applications of Frequency Following Response in Children and Adults. Milaine Dominici Sanfins, Stavros Hatzopoulos ... 8. Non-Conventional Clinical Applications of Otoacoustic Emissions: From Middle Ear Transfer to Cochlear Homeostasis to Access ...
IRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials | HHS.gov
Institutional Review Board Review of Protocol and Informed Consent Changes ... Implementing Protocol Changes Affecting Subjects Already Enrolled in a Clinical Trial Prior to Obtaining IRB Approval As noted ... IRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials. September 29, 2008 ... regarding the implementation of changes to protocols and informed consent documents for NCI/CTEP-sponsored clinical trials in a ...
IRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials | HHS.gov
Institutional Review Board Review of Protocol and Informed Consent Changes ... Implementing Protocol Changes Affecting Subjects Already Enrolled in a Clinical Trial Prior to Obtaining IRB Approval As noted ... IRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials. September 29, 2008 ... HHS Home > OHRP > IRB Review of Protocol & Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials ...
Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis | American Academy of Pediatrics
Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis. Hugo A. Heij and Martin Offringa ... Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis ... Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis ... Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis ...
ICON Further Enhances Clinical Trial Feasibility, Protocol Optimisation And Patient Recruitment Capabilities With TriNetX -...
ICON Further Enhances Clinical Trial Feasibility, Protocol Optimisation And Patient Recruitment Capabilities With TriNetX. ICON ... TriNetX enables researchers to find the right patients at the right sites for clinical trials. For more information, visit http ... It follows ICONs application of cognitive computing capabilities to clinical trial feasibility and patient recruitment. ICONs ... The company specialises in the strategic development, management and analysis of programs that support clinical development - ...
Protocol: Phytomedicine-AMARGOL®, Clinical Trial for Efficacy Proof on Therapeutics - Full Text View - ClinicalTrials.gov
Frontiers | Rehabilitation of Upper Extremity Nerve Injuries Using Surface EMG Biofeedback: Protocols for Clinical Application ...
The aim of this paper was to present structured rehabilitation protocols in two different patient groups with upper extremity ... The rehabilitation protocol for group 1 included guided sEMG training to facilitate initial movements, to increase awareness of ... The rehabilitation protocol for group 1 included guided sEMG training to facilitate initial movements, to increase awareness of ... The aim of this paper was to present structured rehabilitation protocols in two different patient groups with upper extremity ...
Standardized protocols would greatly enhance clinical and research potenti... ( An expert working group of the Inter...)
... protocols,would,greatly,enhance,clinical,and,research,potential,of,BTMs,biological,biology news articles,biology news today, ... In clinical practice BTMs are used to monitor osteoporosis treatment....In its position paper* the Joint IOF-IFCC Bone Marker ... Standardized protocols would greatly enhance clinical and research potential of BTMs. ...An expert working group of the ... Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols. 9. Cold Spring Harbor Protocols features RNA ...
Anticipating Tensions Between Clinical Care and Study Protocol
Clinical management. * The Globalization of Clinical Data in Medtech * Noteworthy Clinical Trends in Med Device to Watch in ... In a clinical trial, if they differ from the investigational plan and havent been approved by the Sponsor, theyre protocol ... Anticipating Tensions Between Clinical Care and Study Protocol 3 October, 2017 Laurie Meehan, Social Media Manager; Polaris ... Clinical Solution Overview Clinical Management Trial Master File Trial Software Laboratory QMS TMF Checklist ...
Multiplex PCR Protocol for the Diagnosis of Staphylococcal Infection | Journal of Clinical Microbiology
To determine whether our protocol could be used for the direct analysis of clinical samples, we carried out a study in which ... The utility of the protocol for the analysis of clinical samples was verified by analysis of aliquots taken directly from BacT/ ... The utility of our protocol for the direct analysis of clinical samples was tested using samples taken from positive BacT/Alert ... Although we evaluated a number of protocols for the isolation of template DNA, the CTAB protocol was the only one that yielded ...
Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol | Diabetes
Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol. ... Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol ... Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol ... Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol ...
TrialsAnalyzing clinical trialTrial protocolsOutcomePreclinical and clinicalAdherenceMethodsPractice2020Deviate from the protocolInvestigatorsJournal of ClinicalStudiesConductEvaluationAssessmentEnrollmentTreatment protocolsImplementationImplicationsVentilator-weaningHigh-dose acetaminophenDevelopment2018GuidelinesParticipantsOncologyCliniciansPharmacologyCentreFeasibilityAcuteEvaluateManagement protocolsSpecimensMaturationStudy ProtocolConclusionsResearch fellowMeasurementDataContent of a clinicalDiagnosisColorectal CancerLaboratoryResultsPopulationsEffectivenessMechanical ventilationEfficacyFacilitatorsRehabilitationFindings25,000PhaseSubjectsFacilitateViralRegulatoryOrganization
Trials57
- As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
- It is important to keep in mind that these algorithms have not been directly compared in clinical trials. (aace.com)
- Treatment effectiveness score as an outcome measure in clinical trials. (clinicaltrials.gov)
- Applicants conducting phase 2 or 3 clinical trials that require Investigational New Drug applications (IND) or Investigational Device Exemption (IDE) applications can use a NIH-FDA template with instructional and sample text to help write protocols. (nih.gov)
- The tool provides a suggested format for phase 2 and 3 clinical trials funded by NIH that are being conducted under an FDA IND or IDE Application. (nih.gov)
- QIBA is an RSNA-sponsored initiative to advance quantitative imaging and the use of imaging biomarkers in clinical trials by reducing variability. (prnewswire.com)
- Today, the verification and quality assurance of all data submission occurs manually and after the images have been submitted, adding another expense, and opportunity for error, to the ever increasing costs and delays of clinical trials. (prnewswire.com)
- AG Mednet automates, expedites and improves outcomes in clinical trials by ensuring quality and compliance within critical medical imaging processes. (prnewswire.com)
- Founded in 2005, AG Mednet is the leading quality compliance partner for image data submission and collection for pharmaceutical, biotechnology and medical device companies, imaging core labs and clinical research organizations managing clinical trials globally. (prnewswire.com)
- These clinical studies include influenza 'challenge studies' as well as natural history studies and phase I trials involving vaccines for viruses carried by mosquitos such as Zika or Dengue virus. (clinicaltrials.gov)
- This article describes the systematic development and scope of SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013, a guideline for the minimum content of a clinical trial protocol.The 33-item SPIRIT checklist applies to protocols for all clinical trials and focuses on content rather than format. (nih.gov)
- Clinical trials / research studies gives a clinician many answers to questions from the point of prevention, detection, diagnosis, control and treatment of illness or a condition such as cancer. (medindia.net)
- Clinical trials or research is done when there is some reason to believe that the treatment being studied may be valuable to the patient. (medindia.net)
- Reasons for Premature Conclusion of Late Phase Clinical Trials: An Analysis of ClinicalTrials.gov Registered Phase III Trials. (medindia.net)
- Investigation of the Influencing Factors on the Incidence of Vertebral Fracture: A Meta-analysis Based on Placebo Data of Randomized Clinical Trials. (medindia.net)
- Kenji Yasukawa , Ph.D., 'Astellas') today announced amendments to the protocols for two registrational Phase 3 trials, ARCHES and EMBARK, designed to evaluate the safety and efficacy of XTANDI ® (enzalutamide) in men with hormone-sensitive prostate cancer (HSPC). (prnewswire.com)
- We continually strive to design and implement clinical trials that bring innovations to people with the greatest need,' said Steven Benner , M.D., senior vice president and global therapeutic area head, Oncology Development, Astellas. (prnewswire.com)
- On April 7, 2008 CTEP issued its first Action Letter under the revised CTEP procedures to investigators conducting CTEP/NCI-sponsored clinical trials involving the use of lapatinib (IND 70252). (hhs.gov)
- TriNetX enables researchers to find the right patients at the right sites for clinical trials. (thestreet.com)
- SYNH ), the only fully integrated biopharmaceutical solutions organization, and Protocol First, Inc., a software solutions provider focused on accelerating clinical research, today announced a novel strategic partnership aimed at driving faster, more efficient clinical trials. (benzinga.com)
- Protocol First has been a leader in developing next-generation technology solutions for complex clinical trials, and we're pleased that we could extend our partnership to improve patients' lives. (benzinga.com)
- It is a harbinger of the transformation of clinical research to a digital model that ensures end-to-end data traceability in the most complex 'precision medicine' trials, while supporting remote and decentralized study execution," said Hugh P. Levaux, Ph.D., Founder and CEO for Protocol First. (benzinga.com)
- Protocol First, Inc., founded in 2015 and headquartered in Salt Lake City, UT, develops next-generation technology solutions for complex clinical trials in the Life Sciences industry. (benzinga.com)
- To facilitate harmonised reporting of outcomes in published trial protocols and reports, the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT) is under development. (bmj.com)
- The endorsed technical documents are aimed at empowering and developing a critical mass of technical capacity of scientists in Africa to conduct proper clinical trials to ensure quality, safety and efficacy of traditional medicines in line with international standards. (who.int)
- In addition, the results of this double-blinded clinical trial will shed new light on our understanding of acupuncture point specificity, and development of methodologies in clinical trials of acupuncture treatment. (nih.gov)
- Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you. (centerwatch.com)
- Worldwide Clinical Trials is recognized for protocol and feasibility evaluations that are accurate, comprehensive, and insightful. (worldwide.com)
- Methodological rigor integrated with operational acumen is at the heart of protocol development at Worldwide Clinical Trials. (worldwide.com)
- We apply it from first-in-man trials and proof-of-concept paradigms through to peri-approval investigations designed to establish a basis for reimbursement decision or highlight clinical attributes of a new product prior to commercialization. (worldwide.com)
- Worldwide Clinical Trials has access to more than 2,500 validated assays. (worldwide.com)
- Clinical Trials can do for you. (worldwide.com)
- Thank you for your interest in Worldwide Clinical Trials. (worldwide.com)
- This course served as a useful introduction to the issues of translating clinical trials. (proz.com)
- This website provides access to information from Astellas sponsored clinical trials and the purpose is not to promote or advertise any. (astellas.com)
- NEW YORK and TOKYO, Aug. 22, 2018 /PRNewswire/ -- Pfizer Inc. (NYSE: PFE) and Astellas Pharma Inc. (TSE: 4503, President and CEO: Kenji Yasukawa, Ph.D., "Astellas") today announced amendments to the protocols for two registrational Phase 3 trials, ARCHES and EMBARK, designed to evaluate the safety and efficacy of XTANDI ® (enzalutamide) in men with hormone-sensitive prostate cancer (HSPC). (astellas.com)
- Methods Based on a prospectively registered protocol, we systematically reviewed the literature and selected randomised or quasi-randomised controlled trials comparing procalcitonin based protocols to initiate or discontinue antibiotics in patients presenting with AECOPD versus standard care. (bmj.com)
- Procalcitonin-based protocols used in all included trials were similar. (bmj.com)
- Clinical trial managers historically relied on internal experience to determine how much to pay physicians for performing clinical trials. (marketwired.com)
- Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. (clinicalconnection.com)
- Learn more about clinical research and participating in a study at About Clinical Trials . (clinicalconnection.com)
- ClinicalConnection.com is a resource that provides information on clinical trials and other research opportunities worldwide. (clinicalconnection.com)
- Cancer is currently the second leading cause of death in the USA, however many gains are being made in cancer therapeutics due in large part to patient participation in clinical trials. (aacrjournals.org)
- A review of blood pressure measurement protocols among hypertension trials: implications for "evidence-based" clinical practice. (g-i-n.net)
- Time to initiation of weaning trials was 2 ICU days in the nurse-driven protocol group, whereas it was 3 days in the physician group. (freecme.com)
- A majority of previous studies on weaning protocols have examined respiratory therapists taking responsibility or ICU physicians directing weaning trials. (freecme.com)
- To provide focused interactive training in ADRD clinical trials to a diverse cadre of investigators. (springer.com)
- The Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD) is a novel multidisciplinary clinical trial training program funded by the National Institute on Aging and the Alzheimer's Association with two educational tracks. (springer.com)
- The Fellowship track includes current and future principal investigators and focuses on the design, conduct and analysis of ADRD clinical trials. (springer.com)
- K ey to the US National Plan to Address Alzheimer's Disease and Related Dementias (ADRD) will be clinical trials of therapies that are capable of slowing or preventing the onset of symptoms ( 1 ). (springer.com)
- Diversifying study teams is a core component of the mission of the Alzheimer's Clinical Trials Consortium (ACTC). (springer.com)
- The ACTC's Inclusion, Diversity, and Education in Alzheimer's disease Clinical Trials (IDEA-CT) Committee is charged with developing goals, formulating a strategic plan, and serving as a source of oversight to support the ACTC's core values of inclusion, diversity and training in ADRD clinical trials. (springer.com)
- To address these needs and goals, members of the ACTC IDEA-CT committee developed the Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD). (springer.com)
- Working independently and under general supervision, the Clinical Trial Protocol Coordinator will support their department/trial(s) in the administrative day to day project activities of TIMI trials (both nationally and internationally) following good clinical practices, regulatory requirements and sponsors/TIMI standards to ensure compliance for the TIMI Study Group. (americasjobexchange.com)
- Two randomized double-blind clinical trials in patients with acute ischemic stroke have shown that treatment with a daily dose of 6 g acetaminophen (paracetamol) results in a small but rapid and potentially worthwhile reduction of 0.3°C (95% CI: 0.1-0.5) in body temperature. (pubmedcentralcanada.ca)
- We conducted two randomized, placebo-controlled clinical trials to study whether early treatment with acetaminophen reduces body temperature in patients with acute ischemic stroke confined to the carotid territory. (pubmedcentralcanada.ca)
- Collette Lindley, Research Assistant at the SRC stated: "Our validated methods for clinical trials require a large throughput of growth media types and dilution replicates with up to 16 spiral plates for each subject for each study visit. (selectscience.net)
Analyzing clinical trial1
- Combining these approaches allows the companies to address customer nuances related to trial protocols, capturing and analyzing clinical trial data faster and more efficiently with the goal of accelerating product time-to-market. (benzinga.com)
Trial protocols2
- To facilitate the development of clinical trial protocols that require a Food and Drug Administration (FDA) Investigational New Drug (IND) or Investigational Device Exemption (IDE) Application, the NIH and FDA collaboratively developed a Phase 2/3 Clinical Trial Protocol Template and an electronic protocol-writing tool to help investigators think through the scientific basis of their assumptions, minimize uncertainty in the interpretation of outcomes, and prevent loss of data. (nih.gov)
- However, trial protocols and existing protocol guidelines vary greatly in content and quality. (nih.gov)
Outcome4
- This Protocol encourages a cards-on-the-table approach when something has gone wrong with a claimant's treatment or the claimant is dissatisfied with that treatment and/or the outcome. (justice.gov.uk)
- Some studies showed that children with myeloid-positive ALL had a poorer clinical outcome compared with those of myeloid-negative ALL patients [ 10 , 18 , 19 ]. (hindawi.com)
- Taken one step further, risk is minimized by helping ensure patient safety and outcome through proper application of appropriate standards of care (effective protocols) and good clinical judgment (effective training) by competent clinicians (effective hiring) using safe equipment (effective fleet and equipment maintenance). (emergencydispatch.org)
- In the original protocol, the primary outcome measure is a dichotomized score on the modified Rankin Scale (mRS) [ 2 ] assessed at 3 months from onset of symptoms, with good functional outcome defined as a score of 0-2 and poor functional outcome as a score of 3-death. (pubmedcentralcanada.ca)
Preclinical and clinical2
- Electroporation Protocols: Preclinical and Clinical Gene Medicine, Second Edition provides in-depth knowledge on the delivery of naked DNA and small-interfering RNA (siRNA) to the targeted cells, tissues, and animals for prevention and treatment of disease. (mexmat.ru)
- Ibudilast's anti-neuroinflammatory and neuroprotective actions have been demonstrated in preclinical and clinical study results and provide the rationale for its potential therapeutic utility in neurodegenerative diseases (e.g., progressive MS and ALS), substance abuse/addiction and chronic neuropathic pain. (cnbc.com)
Adherence2
- He also noted that standardised protocols would greatly increase the clinical and research potential of BTMs, with improved value in patient management and other uses, such as prediction of the rate of bone loss, identification of secondary osteoporosis, prediction of response to therapy, and in improving treatment adherence. (redorbit.com)
- A computerized Decision Support Systems (DSS) can improve the adherence of the clinicians to clinical guidelines and protocols. (springer.com)
Methods8
- Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. (springer.com)
- Authoritative and cutting-edge, Pre-Clinical Models: Techniques and Protocols aims to provide methods that describe the context of specific disease or therapeutic areas. (springer.com)
- Protocols in Biochemistry and Clinical Biochemistry offers clear, applied instruction to fundamental biochemistry methods and protocols, from buffer preparation to nucleic acid purification, protein, lipid, carbohydrate, and enzyme testing, and clinical testing of vitamins, glucose and cholesterol levels, among other diagnostics. (researchandmarkets.com)
- Each protocol is illustrated with step-by-step instructions, labeled diagrams, and color images, as well as a thorough overview of materials and equipment, precursor techniques, safety considerations and standards, analysis and statistics, alternative methods and troubleshooting. (researchandmarkets.com)
- MATERIALS AND METHODS This longitudinal human clinical trial is designed as a prospective study, to measure implant stability with the resonance frequency analyzer (Osstell, Integration Diagnostics AB, Sweden) at time of implant placement and up to 16 weeks post placement. (clinicaltrials.gov)
- The study reviews all of the generally accepted clinical analytical methods that are currently in use today for measuring HbA1c levels. (prnewswire.co.uk)
- Methods Seventy-five football players with an acute hamstring injury, verified by MRI, were randomly assigned to one of two rehabilitation protocols. (bmj.com)
- METHODS: Subjects were alternately allocated management according to one of two protocols: one without (group A) and one with (group B) immediate access to results of basic laboratory tests. (bmj.com)
Practice13
- In clinical practice, BTMs are used to monitor osteoporosis treatment. (redorbit.com)
- Professor John Kanis, IOF President, urged the adoption of the reference standards by the scientific community, "Without precluding the use of other BTMs, the adoption of these reference standards would facilitate comparison between studies and allow data from different studies to be pooled in order to facilitate their incorporation into routine clinical practice. (redorbit.com)
- Clinical endocrinologists worldwide rely on Endocrine Practice, the official journal of the American Association of Clinical Endocrinologists (AACE), to keep them on the leading edge of treatment of patients with endocrine diseases. (aace.com)
- Members of AACE are physicians with special education, training and interest in the practice of clinical endocrinology. (aace.com)
- Variation in clinical practice is due in part to clinicians' poor compliance with guidelines and recommended therapies. (nih.gov)
- It is not likely to be concerned with minor or technical shortcomings (see paragraph 4.3 to 4.5 of the Practice Direction on Pre-Action Conduct and Protocols). (justice.gov.uk)
- Protocol trumps practice. (mastercontrol.com)
- When deciding whether or not to conduct a particular study, a PI needs to verify that the protocol is aligned with practice norms. (mastercontrol.com)
- This protocol will provide greater support to their practice and to contribute to the early detection of precursor lesions and consequent decrease of the incidence of cervical cancer, as well as promote a better quality of care to clients. (scielo.br)
- At this time, Advanced Practice Registered Nurse (APRN) clinicals cannot be substituted with virtual assignments, so clinical hours will need to be arranged with the faculty and assignments will be based on space availability. (oakland.edu)
- First, it may not correspond with everyday clinical practice. (pubmedcentralcanada.ca)
- Her main research interests include cultural differences in illness presentations, cognitive profiles in eating disorders, and experimental work in emotion processing and translational research from experimental findings to real clinical practice. (wikipedia.org)
- Tchanturia's research primarily concerns the cognitive and socio-emotional aspects of eating disorders, implementing positive psychology in clinical practice. (wikipedia.org)
20201
- With these changes, the estimated primary completion date for the EMBARK clinical trial is mid-2020. (prnewswire.com)
Deviate from the protocol2
- Researchers blur the distinction themselves when they conduct procedures that are consistent with clinical care but deviate from the protocol. (mastercontrol.com)
- All studies were open-labelled or single blinded and the final decision to administer or withhold antibiotic was left to the responsible clinician, who could deviate from the protocol. (bmj.com)
Investigators6
- For more information about AG Mednet's SQC for QIBA and its work with clinical research organizations, imaging trial sponsors, imaging core labs and principal investigators, please visit www.agmednet.com . (prnewswire.com)
- This study is a collaborative effort between MediciNova, Inc. and Drs. Nazem Atassi and Haruhiko Banno, Principal Investigators at Massachusetts General Hospital's (MGH) Neurological Clinical Research Institute (NCRI) and Harvard Medical School to measure the effects of MN-166 on reducing brain microglial activation utilizing a biomarker in 15 subjects with ALS. (cnbc.com)
- The Sunshine Act has changed how companies and trial managers pay clinical investigators," said Ryan McGuire, Head of Research at Cutting Edge Information. (marketwired.com)
- It also examines common milestone payments, the number of payments made to clinical investigators and ranges and averages of direct costs that investigators often pass through to sponsors. (marketwired.com)
- In addition, the investigators were wise to survey the intensivists who staff this ICU on their perceptions of the nurse-managed weaning protocol since they ultimately gave the "green light" to proceed with extubation. (freecme.com)
- The low availability of ADRD trialists, including clinical investigators, statisticians, and other experts represents a threat to the national ADRD research agenda. (springer.com)
Journal of Clinical2
Studies20
- More importantly, it identifies research priorities and recommends that specific markers be used as reference analytes for BTMs in clinical and observational studies. (redorbit.com)
- It recommends that specific markers of bone formation (s-PINP) and of bone resorption (s-CTX) be used as reference analytes for bone turnover markers in clinical and observational studies. (redorbit.com)
- Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. (clinicaltrials.gov)
- The Laboratory of Infectious Diseases (LID) Clinical Studies Unit (CSU) enrolls healthy volunteers into clinical studies to study infectious diseases. (clinicaltrials.gov)
- The LID CSU performs clinical studies to learn about these viral infections and assist in the development of vaccines and treatments for the infections. (clinicaltrials.gov)
- Previous human challenge studies have addressed some aspects of the natural history by evaluating the timing of viral replication, shedding, clinical symptoms, and innate and adaptive immune responses. (clinicaltrials.gov)
- While initially the protocol was designed to screen participants for influenza challenge studies, we have expanded our scope of research to include emerging and re-emerging infectious diseases.The primary goal of this study is to collect and store serum and RNA samples and obtain clinical and laboratory data from volunteers to determine in advance if they are potentially eligible to participate in future clinical studies. (clinicaltrials.gov)
- To accomplish this objective, up to 5000 participants will be enrolled in this protocol at the NIH Clinical Center clinic or day hospital in order to maintain a pool of participants who have been evaluated and can be screened for future LID Clinical Studies protocols. (clinicaltrials.gov)
- Computerized protocols for mechanical ventilation and management of intravenous fluid and hemodynamic factors in patients with the acute respiratory distress syndrome provide case studies for this discussion. (nih.gov)
- Comprehensive MRI protocol for stroke management: Tissue sodium concentration as a measure of tissue viability in a non‐human primate model and clinical studies. (currentprotocols.com)
- Seizure occurred in 0.4% of patients receiving XTANDI in clinical studies. (prnewswire.com)
- Apparent dramatic reductions were achieved in both parameters by performing imaging studies in all patients with equivocal clinical findings. (aappublications.org)
- The company specialises in the strategic development, management and analysis of programs that support clinical development - from compound selection to Phase I-IV clinical studies. (thestreet.com)
- Clinical protocols for osteopathic manipulative treatment (OMT) procedures have been used in "technique" studies to examine the effects of specific procedures. (jaoa.org)
- In my opinion, in technique studies based on protocols for OMT procedures, manipulations are not delivered in a manner consistent with osteopathic principles, and there may be unforeseen consequences of such research-whether findings for the procedures are positive or negative. (jaoa.org)
- This TUViD-VM protocol can be used in metagenomic and virome studies to increase the likelihood of detecting viruses from any biological source. (cdc.gov)
- The discrepancies between studies may be related to the use of different treatment protocols [ 20 ], different populations, as well as different definition criteria of myeloid-positive ALL, which are summarized in Table 1 . (hindawi.com)
- Few studies to date have evaluated the effectiveness of different treatment protocols for acute hamstring injuries in athletes. (bmj.com)
- In addition to spiral plates for clinical studies, we also use pour plates and filtration membranes in our in vitro studies. (selectscience.net)
- Based on findings from their qualitative studies that mapped out the needs for the three stakeholders, Tchanturia and colleagues collaboratively engaged people with lived experience, carers, and clinicians from the National Eating Disorder Service to develop the PEACE clinical pathway. (wikipedia.org)
Conduct7
- 1.4 This Protocol is now regarded by the courts as setting the standard of normal reasonable pre-action conduct for the resolution of clinical disputes. (justice.gov.uk)
- 1.5.1 This Protocol sets out the conduct that prospective parties would normally be expected to follow prior to the commencement of any proceedings. (justice.gov.uk)
- The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting, and appraisal. (nih.gov)
- The study protocol refers to the 'recipe' used to conduct a study des. (bio-medicine.org)
- The study protocol refers to the 'recipe' used to conduct a study, describes what will be done during the study, how this will be done and why it is being done. (bio-medicine.org)
- Advise sites on protocol conduct, interpretation of protocols and ensures resolution of issues as applicable per department/trial. (americasjobexchange.com)
- Demonstrate and maintain knowledge of regulations, clinical research conduct, laws, guidelines and standards relating to department/trial(s). (americasjobexchange.com)
Evaluation5
- This reasoning is the basis of an explicit method of decision support that allows the rigorous evaluation of interventions, including use of the protocols themselves. (nih.gov)
- We are very pleased that this important regulatory step is now completed as we can continue clinical evaluation of MN-166 in the treatment of ALS. (cnbc.com)
- Evaluation of the clinical and economic impact after the protocol change of basiliximab use in orthohepatic transplant. (isciii.es)
- EISS implemented an evaluation protocol to assess the quality of clinical data collected by sentinel networks for the surveillance of influenza. (eurosurveillance.org)
- Evaluation of two clinical protocols for the management of women with vaginal discharge in southern Thailand. (bmj.com)
Assessment3
- Using data from eight Community Care Access Centres (CCACs) in Ontario, we demonstrate that an automatic, data-driven, machine learning algorithm such as the K nearest neighbors (KNN) algorithm can predict rehabil itation potential more effectively than the current Clini cal Assessment Protocol (CAP). (actapress.com)
- Full clinical assessment including speculum examination and microbiological assessment for infection with gonorrhoea, chlamydia, candida, trichomonas, and bacterial vaginosis was performed on all women. (bmj.com)
- Follow up assessment of clinical and microbiological response was performed 1-2 weeks later. (bmj.com)
Enrollment4
- As you know, on March 20, 2008 CTEP issued a memorandum to NCI/CTEP-sponsored cooperative groups explaining implementation of revised CTEP procedures for handling amendments to cooperative group protocols and enrollment of new subjects in these protocols in situations in which new or modified risk information is considered to represent no more than a minor alteration in the overall risk-benefit relationship for subjects. (hhs.gov)
- whether suspensions of new subject enrollment by CTEP pending IRB approval of protocol and informed consent document changes need to be reported to OHRP. (hhs.gov)
- To inform understanding of the potential efficacy and safety of hydroxychloroquine-azithromycin, we strongly advocate for enrollment of all patients who are candidates into IRB-approved clinical research protocols. (acc.org)
- We hypothesize that a provider-directed intervention will increase rates of cancer clinical trial enrollment amongst African-Americans. (aacrjournals.org)
Treatment protocols2
- The building of a prescriptive DSS based on breast cancer treatment protocols and its integration with a legacy Electronic Patient Record is the aim of the Oncocure project. (springer.com)
- Failure of bedside hospital clinical staff to follow established treatment protocols has been identified as a common factor in patients having an adverse event during their hospitalisation. (bmj.com)
Implementation3
- Dr. Ken Leslie, scientist at Lawson, associate professor in the Department of Surgery at Schulich Medicine & Dentistry, and Chair/Chief of the Division of General Surgery at London Health Sciences Centre led the implementation of the new protocol. (eurekalert.org)
- Implementation of a nurse-driven protocol for weaning patients resulted in shortened duration of mechanical ventilation, shorter ICU stays, and a higher rate of successful weaning, with ICU physicians reporting a generally positive attitude toward nurses being responsible for protocol-directed weaning. (freecme.com)
- The nurses participated in protocol training and education sessions prior to implementation of the protocol, with a 1-month pilot period to gain familiarity with the protocol and to standardize communication with physicians. (freecme.com)
Implications2
- No protocol or proposed program is recommended without full knowledge of the logistical and financial implications in addition to the clinical and regulatory implications. (worldwide.com)
- Implications for clinical decision-making and computerized health information sys tems are discussed. (actapress.com)
Ventilator-weaning1
- A prospective study design was used to compare retrospective data from a specific 6-month period of physician-directed weaning outcomes with patient outcomes during a 6-month prospective period of the nurse-driven ventilator weaning protocol. (freecme.com)
High-dose acetaminophen2
- Paracetamol (Acetaminophen) In Stroke (PAIS) is a randomized, double-blind clinical trial, comparing high-dose acetaminophen with placebo in 2500 patients. (pubmedcentralcanada.ca)
- The Paracetamol (Acetaminophen) In Stroke (PAIS) study is a phase III multicenter, double blind, randomized, placebo-controlled clinical trial of high-dose acetaminophen in patients with acute stroke. (pubmedcentralcanada.ca)
Development7
- This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models in a number of medical areas, including metabolic disorders, longevity, cancer, heart disease and psychiatric disorders. (springer.com)
- ICON's use of TriNetX is a further example of our commitment to deploy industry-leading technologies that help customers overcome complex clinical development challenges. (thestreet.com)
- The present study has led to the development of a dynamic pre-clinical testing protocol to quantitatively assess the efficacy of disc replacement devices. (bl.uk)
- Additionally, the spine simulator and testing protocol would provide valuable data during the design stage of new total disc replacements, aiding the development of the next generation of artificial discs. (bl.uk)
- Feasibility data is analyzed, summarized and graphically presented in an executive summary document that provides supporting data and facts clearly, to assist the optimal development of your clinical research program. (worldwide.com)
- The report is a valuable resource for clinical development managers, directors and vice presidents to stay informed on the latest trends around determining clinical investigator FMV. (marketwired.com)
- Findings from literature and market research guided towards the development of a standardized glucose measurementtransmission protocol using a middleware. (joanneum.at)
20181
- The companies now anticipate the primary completion date for the ARCHES clinical trial to be in late 2018. (prnewswire.com)
Guidelines4
- Computerized protocols used to deliver decision support can be configured to contain much more detail than textual guidelines or paper-based flow diagrams. (nih.gov)
- Computer-Based Medical Guidelines and Protocols: A Primer and Current Trends. (springer.com)
- The recommendations will be taken into account during the WHO Regional Office for Europe-initiated revision of its 2007 HIV/AIDS clinical guidelines for the WHO European Region, based on revised global WHO recommendations on ART for adults and adolescents, ART for infants and children, use of ARVs for treatment of HIV-infected pregnant women and infants born to them. (who.int)
- Conclusions Good compliance with UK guidelines for tryptase measurements is achievable in this long-term cohort, but obtaining clinical details at referral remains a challenge. (bmj.com)
Participants2
- But as a researcher, I feel like it's up to me to make sure patients feel empowered as participants in my clinical trial. (ehealthinnovation.org)
- African-Americans are underrepresented amongst cancer clinical trial participants, despite evidence from our institution that African-Americans were more than twice as likely as Caucasians to enroll in a cancer clinical trial when offered. (aacrjournals.org)
Oncology2
- In order to identify potential intervention strategies, we surveyed staff in the Section of Hematology/Oncology at the University of Chicago regarding clinical trial accrual. (aacrjournals.org)
- A short, seven question, survey was distributed to all employees in the Section of Hematology/Oncology who were directly involved in clinical care or research. (aacrjournals.org)
Clinicians1
- however, clinicians must be willing to modify personal styles of clinical management. (nih.gov)
Pharmacology1
- Clinical pharmacology has changed many clinical systems, including anaesthesia delivery in both the hospital and ambulatory surgery settings. (termedia.pl)
Centre3
- The six-month single-centre, single-blinded, controlled switching study with periods of clinical confinement is being conducted in Germany. (bio-medicine.org)
- Synbiosis, a world-leading manufacturer of automated micro-biological systems, today announced its ProtoCOL automated colony counter is being successfully used by the Skin Research Centre (SRC) at the University of Leeds, one of Europe's leading dermatology centres, to rapidly test the effectiveness of new anti-microbial therapies to treat acne, dermatitis and other skin diseases. (selectscience.net)
- Martin Smith for Synbiosis commented:" We are delighted so see the ProtoCOL being used routinely at such a major dermatology centre as the SRC. (selectscience.net)
Feasibility2
- It follows ICON's application of cognitive computing capabilities to clinical trial feasibility and patient recruitment . (thestreet.com)
- Feasibility of the rehabilitation protocols for the two different patient populations was illustrated. (frontiersin.org)
Acute5
- Objective To characterise the clinical features of patients admitted to hospital with coronavirus disease 2019 (covid-19) in the United Kingdom during the growth phase of the first wave of this outbreak who were enrolled in the International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) World Health Organization (WHO) Clinical Characterisation Protocol UK (CCP-UK) study, and to explore risk factors associated with mortality in hospital. (bmj.com)
- The clinical experience of human immunodeficiency virus (HIV) + patients treated with oral atovaquone for acute Pneumocytstis carinii pneumonia (PCP) under a Treatment Investigational New Drug (IND) protocol (mild or moderate PCP) and an Open-Label Study protocol (severe PCP) was evaluated. (rti.org)
- Objective To compare the effectiveness of two rehabilitation protocols after acute hamstring injury in Swedish elite football players by evaluating time needed to return to full participation in football team-training and availability for match selection. (bmj.com)
- There is a lack of clinical research and consensus regarding the effectiveness of various rehabilitation protocols for acute hamstring injuries in football. (bmj.com)
- Results 98% provided two or more acute samples, but only 60% supplied clinical information. (bmj.com)
Evaluate4
- For the final step, four judges were selected to evaluate the clinical protocol according to AGREE 2. (scielo.br)
- The primary objective of the study will be to evaluate the effects of CSP-1103 compared to placebo on clinical decline in subjects with MCI due to AD and who are also positive for amyloid β (Aβ) biomarker. (cnbc.com)
- 1 The quality of published research affects the ability of researchers and stakeholders to evaluate, replicate and build on study findings, which in turn impacts evidence-based clinical and policy decision making. (bmj.com)
- Now, however, companies evaluate a variety of factors including industry benchmarks, historic payment data and trial protocol details. (marketwired.com)
Management protocols3
- DESIGN: Alternate allocation of subjects to one of two management protocols. (bmj.com)
- The National Task Force on Covid-19 has decided against including Itolizumab drug in clinical management protocols for treating the disease even though the DCGI has approved its 'restricted emergency use' in infected patients, official sources said. (business-standard.com)
- A majority of the members of the task force opined that there was not enough evidence currently to get the drug included in the clinical management protocols for Covid-19,' said an official source. (business-standard.com)
Specimens3
- Based on the preceding discussion, the most important considerations with respect to the diagnosis of staphylococcal infections are (i) identification of staphylococci in clinical specimens, (ii) differentiation of S. aureus from the less-pathogenic CNS, and (iii) determination of whether isolates of either group are resistant to oxacillin. (asm.org)
- However, for clinical specimens, such as blood, other fluids, or infected organ tissues, successful detection of viruses is less likely because virus-to-host genome ratios are insufficient ( 3 - 6 ). (cdc.gov)
- Analysis of bronchoalveolar lavage specimens from immunocompromised patients with a protocol applicable in the microbiology laboratory. (asm.org)
Maturation3
- This research topic aims at providing recent findings and reviews to contribute to the maturation of this emerging field with high clinical potential. (frontiersin.org)
- We improved the capacity of clinical-grade monocyte-derived dendritic cells to elaborate IL-12 with special regard of their state of maturation, different maturation stimuli and its regulation by TH1/TH2-influencing cytokines. (egms.de)
- All investigated clinical-grade protocols for maturation of monocyte-derived DC appeared able to provide the phenotypic characteristics necessary to initiate DC maturation. (egms.de)
Study Protocol3
- Any GCP course worth its registration fee will discuss the distinction between standard of care and the study protocol. (mastercontrol.com)
- The SPA request includes the proposed Phase III study protocol, statistical analysis plans and briefing materials along with specific questions from CereSpir to facilitate a meaningful dialogue with the FDA on the proposed study design. (cnbc.com)
- Transcutaneous vagus nerve stimulation for the treatment of depression: a study protocol for a double blinded randomized clinical trial. (nih.gov)
Conclusions3
- Conclusions A rehabilitation protocol emphasising lengthening type of exercises is more effective than a protocol containing conventional exercises in promoting time to return in Swedish elite football. (bmj.com)
- CONCLUSIONS: Both protocols were equally effective in managing women with abnormal vaginal discharge. (bmj.com)
- Conclusions Despite an organisational commitment to the RRS, clinical staff act on local cultural rules within the clinical environment that are usually not explicit. (bmj.com)
Research fellow2
- After relocating to London in 1997, she became a clinical research fellow at the Institute of Psychiatry, King's College London in 1998. (wikipedia.org)
- After relocating to the United Kingdom, Tchanturia worked as a Clinical Research Fellow at Institute of Psychiatry, Psychology and Neuroscience, King's College London from 1998-2003. (wikipedia.org)
Measurement3
- Moreover, it examines clinical measurement devices and reagents as utilized in hospitals, clinics, doctor's offices and at-home care locations. (prnewswire.co.uk)
- Aim was to develop a prototype of an automated glucose measurement transmission protocol based on the Continua DesignGuidelines and to embed the protocol into a CDSS used by healthcare professionals. (joanneum.at)
- A literature and market research was performed to analyze the state-of-the-art and thereupon develop, integrate and validate an automated glucose measurement transmission protocol in an iterative process. (joanneum.at)
Data16
- BOSTON , April 23, 2014 /PRNewswire/ -- Clinical trial sponsors working to standardize the capture and submission of complex imaging data through new QIBA imaging charters now have an easy and effective way to ensure the protocols are being met. (prnewswire.com)
- AG Mednet's Submission, Quality and Compliance (SQC) software for QIBA is the first technology to automate the process of verifying QIBA protocol compliance, saving sponsors time and money and making it easier for investigator sites to submit quality data. (prnewswire.com)
- AG Mednet's SQC software for QIBA protocols removes the manual process and scans imaging data for QIBA compliance in a fraction of the time, at a fraction of the cost. (prnewswire.com)
- AG Mednet provides the market-leading functionality and support to collect clinical trial image data globally, apply advanced, automated quality-assurance processes to ensure the data is protocol-compliant and readily usable, properly de-identify it to ensure regulatory compliance, and deliver it reliably and securely to one or more trial repositories. (prnewswire.com)
- When we looked at the data from this new protocol, we saw that the patient's pain-control was just as good with this pathway, without a huge prescription for narcotics. (eurekalert.org)
- Each data point in the TriNetX system can be traced to healthcare organisations who have the ability to identify individual patients, enabling ICON to develop virtual patient cohorts that can be found in real-world clinical trial settings. (thestreet.com)
- The partnership is expected to optimize data integration with Electronic Health Record Systems and support Remote Source Data Review, further extending a multi-year, pre-existing relationship between Syneos Health and Protocol First. (benzinga.com)
- The collaboration responds to the increasing demand from biopharmaceutical customers for digital solutions that break down silos between Sites, Sponsors, CROs and functional areas to accelerate the collection and review of clinical trial research data. (benzinga.com)
- The enhanced collaboration furthers the ability of Syneos Health to combine Protocol First's proprietary software solutions that integrate data from leading EHR systems into electronic data capture (EDC) with operational insights from Syneos Health Dynamic Assembly ® network - an open ecosystem of best-of-breed data and technology collaborators - to deliver fit-for-purpose customer solutions. (benzinga.com)
- How are mutational data helping inform clinical prognosis and treatment protocol? (ajmc.com)
- The Phase 2 clinical program generated preliminary safety and efficacy data in approximately 100 people, half of whom received CSP-1103 for up to 2 years. (cnbc.com)
- These two separate cohorts are included in one single protocol to enable patient data from these two groups to be entered into a common database, as the current prognostic classifications determining treatment may evolve further with subsequent more detailed molecular analysis of the tumours. (centerwatch.com)
- Also, there are some differences between the beam quality specifiers and data proposed by the two protocols. (oregonstate.edu)
- The TG-51 protocol allows the determination of a more accurate absorbed dose in a ⁶⁰Co beam than the TG-21 protocol since it uses an absorbed dose-to-water calibration factor directly measured, while the exposure based dosimetry system is dependent on external physical data which are not measured in clinics. (oregonstate.edu)
- A fast and accurate data transmission from glucose meter to clinical decision support systems (CDSSs) is crucial for the management of type 2 diabetes mellitus since almost all therapeutic interventions are derived from glucose measurements. (joanneum.at)
- Our clinical trial data is also subject to audit by regulatory authorities at any time. (selectscience.net)
Content of a clinical1
- to develop and validate the content of a clinical protocol aimed at prevention of cervical cancer in primary care. (scielo.br)
Diagnosis5
- Volume 1 primarily focuses on revised clinical protocols and provides information on new research to help guide decisions and criteria regarding diagnosis, management, and treatment of hearing-related issues. (routledge.com)
- 3 American Osteopathic Association (AOA) protocols for the use of OMT state that the "diagnosis must be specific. (jaoa.org)
- 2) To determine clinical and simple laboratory indicators for diagnosis of patients with vaginal discharge in the local setting. (bmj.com)
- Objectives To validate the efficiency of the application of a diagnostic protocol based on the patterns of presentation of uveitis to establish the diagnosis. (bmj.com)
- Inclusion criteria are a clinical diagnosis of hemorrhagic or ischemic stroke and the possibility to start treatment within 12 hours from onset of symptoms. (pubmedcentralcanada.ca)
Colorectal Cancer1
- An exploratory study of the follow-up care needs of patients treated for colorectal cancer," Journal of Clinical Nursing , vol. 19, pp. 3291-3300, 2010. (hindawi.com)
Laboratory3
- An expert working group of the International Osteoporosis Foundation (IOF) and the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) has released a new position paper which reviews the evidence of bone turnover markers (BTMs) in fracture risk prediction and monitoring of osteoporosis therapy. (redorbit.com)
- OBJECTIVES: (1) To compare the effectiveness of two clinical protocols for the management of vaginal discharge in the situations where no laboratory facilities are available but speculum examination is possible and where basic laboratory facilities are available. (bmj.com)
- Simple clinical indicators for candidiasis, bacterial vaginosis, or trichomonas as in protocol A are sufficiently sensitive and specific for use in situations with no laboratory support. (bmj.com)
Results6
- The purpose of this study is to detect increasing medication dose results in heroin cessation for patients still using, to determine if decreasing medication dose in patients unable to tolerate medication dose increases retention, and to determine if blood levels of methadone or buprenorphine correlate with clinical response. (clinicaltrials.gov)
- Now a second clinical study will assess whether this reduced exposure is maintained over the longer term, and also whether longer term exposure reduction results in detectable changes in biological effect. (bio-medicine.org)
- Total disc replacement has emerged as a viable treatment but the complexity of the spine is reflected in the clinical results, which trail far behind the success of hip and knee arthroplasty. (bl.uk)
- Results Time to return was significantly shorter for the players in the L-protocol, mean 28 days (1SD±15, range 8-58 days), compared with the C-protocol, mean 51 days (1SD±21, range 12-94 days). (bmj.com)
- The results of the study show a discrepancy between the absorbed dose-to-water determined according to TG-21 and TG-51 protocols of about 1.4% and 1.7% for 6 and 18 MV photon beams, respectively. (oregonstate.edu)
- We divided the results into four categories, patient barriers, provider barriers, protocol barriers and health system barriers. (aacrjournals.org)
Populations1
- TriNetX offers robust query and analytics tools that enable real-time analyses of patient populations which are helping our customers design better protocols, select the right sites and recruit patients faster. (thestreet.com)
Effectiveness1
- In this meta-analysis we assessed safety and clinical effectiveness of procalcitonin-based protocols to initiate or discontinue antibiotics in patients presenting with AECOPD. (bmj.com)
Mechanical ventilation3
- Nurse-driven, protocol-directed weaning from mechanical ventilation improves clinical outcomes and is well accepted by intensive care unit physicians. (freecme.com)
- The purpose of this study was to compare the usual method of physician-directed weaning from mechanical ventilation to a weaning protocol directed and managed by bedside ICU nurses. (freecme.com)
- Main outcomes for comparison included duration of mechanical ventilation (days), ICU length of stay, ventilator-associated pneumonia (VAP) rates, hospital mortality, and physician attitudes toward the nurse-managed protocol. (freecme.com)
Efficacy1
- A study demonstrating the efficacy of their protocol is being presented at the American College of Surgeons Clinical Congress in Boston, Massachusetts on October 24. (eurekalert.org)
Facilitators1
- The survey queried respondents about their opinions on the current impediments to and facilitators of cancer clinical trial accrual at the University of Chicago as well as asking for their opinions on ways to improve the process. (aacrjournals.org)
Rehabilitation4
- The aim of this paper was to present structured rehabilitation protocols in two different patient groups with upper extremity nerve injuries using sEMG biofeedback. (frontiersin.org)
- The rehabilitation protocol for group 1 included guided sEMG training to facilitate initial movements, to increase awareness of the new target muscle, and later, to facilitate separation of muscular activities. (frontiersin.org)
- Study design Prospective randomised comparison of two rehabilitation protocols. (bmj.com)
- The primary objective of all rehabilitation protocols is to return the player as soon as possible to the prior level of performance with a minimal risk of injury recurrence. (bmj.com)
Findings3
- When treatment in a clinical technique study is not based on the findings of a patient's medical history and physical examination, how can we be practicing osteopathic medicine or be studying the effects of a truly osteopathic manipulative procedure? (jaoa.org)
- Without complete reporting of the outcomes studied, evidence-based clinical and policy decisions are limited and researchers cannot synthesise, replicate or build on existing research findings. (bmj.com)
- DISCUSSION: These findings suggest sensorimotor control disturbances in individuals with chronic idiopathic neck pain may not be present, spawning debate on the clinical usefulness of these tests. (medworm.com)
25,0001
- We bring together approximately 25,000 clinical and commercial minds with the ability to support customers in more than 110 countries. (benzinga.com)
Phase2
- Revisions were also made to the protocol for EMBARK, a randomized Phase 3 study of enzalutamide plus leuprolide, enzalutamide monotherapy, and leuprolide alone in men with high-risk non-metastatic HSPC. (prnewswire.com)
- The proposed Phase 3 clinical trial is designed as an adequate and well controlled, double-blind, adaptive design, placebo-controlled multinational study of CSP-1103 administered to subjects with MCI due to AD who have biomarker evidence supporting this condition. (cnbc.com)
Subjects2
- Your human subjects study may meet the NIH definition of a clinical trial. (nih.gov)
- The plate counts generated are then used to determine which treatments are the most effective at reducing the number of microorganisms associated with diseases on the skin of clinical trial subjects. (selectscience.net)
Facilitate1
- By providing guidance for key content, the SPIRIT recommendations aim to facilitate the drafting of high-quality protocols. (nih.gov)
Viral2
- In this study, we quantifiably and extensively compared classical and modern experimental approaches for virus purification and enrichment to finalize a protocol for unbiased detection of emerging viruses directly from organ tissues (tissue-based unbiased virus detection for viral metagenomics [TUViD-VM]) for an increased signal-to-noise ratio (ratio of virus genome to host genome) in virus detection. (cdc.gov)
- Schematic description of tissue-based universal virus detection for viral metagenomics protocol. (cdc.gov)
Regulatory1
- RESEARCH TRIANGLE PARK, NC --(Marketwired - December 18, 2014) - Today's strict regulatory environment necessitates that pharmaceutical companies adhere to clinical investigator fair market value (FMV) for trial-related compensation. (marketwired.com)
Organization3
- Join the world's largest organization that represents clinical endocrinologists, with over 6,500 members in the United States and 97 other countries. (aace.com)
- A common protocol structure and organization facilitates protocol review by oversight entities. (nih.gov)
- Never developed in isolation, all our protocols are fully verified through the operational components of the organization. (worldwide.com)