AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureHumanitiesInformation ScienceHealth Care
Clinical ProtocolsGenetic TherapyNeoplasmsReproducibility of ResultsMagnetic Resonance ImagingTreatment OutcomeOsteoporosisFractures, BoneBone DensityOsteoporotic FracturesChemistry, ClinicalBone RemodelingOsteoporosis, PostmenopausalSaccadesVisual CortexThumbMotor CortexEye MovementsPhotic StimulationBrain MappingPhenylthiohydantoinSterol EsteraseEthical ReviewDrug IndustryEthics Committees, ResearchHypopituitarismAndrostenolsNewspapersBone Density Conservation AgentsMass Media
Clinical Protocols
Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy.
Genetic Therapy
Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Magnetic Resonance Imaging
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Treatment Outcome
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Osteoporosis
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
Fractures, Bone
Breaks in bones.
Bone Density
The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.
Osteoporotic Fractures
Breaks in bones resulting from low bone mass and microarchitectural deterioration characteristic of OSTEOPOROSIS.
Chemistry, Clinical
The specialty of ANALYTIC CHEMISTRY applied to assays of physiologically important substances found in blood, urine, tissues, and other biological fluids for the purpose of aiding the physician in making a diagnosis or following therapy.
Bone Remodeling
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Osteoporosis, Postmenopausal
Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.
Saccades
An abrupt voluntary shift in ocular fixation from one point to another, as occurs in reading.
Visual Cortex
Area of the OCCIPITAL LOBE concerned with the processing of visual information relayed via VISUAL PATHWAYS.
Thumb
The first digit on the radial side of the hand which in humans lies opposite the other four.
Motor Cortex
Area of the FRONTAL LOBE concerned with primary motor control located in the dorsal PRECENTRAL GYRUS immediately anterior to the central sulcus. It is comprised of three areas: the primary motor cortex located on the anterior paracentral lobule on the medial surface of the brain; the premotor cortex located anterior to the primary motor cortex; and the supplementary motor area located on the midline surface of the hemisphere anterior to the primary motor cortex.
Eye Movements
Voluntary or reflex-controlled movements of the eye.
Photic Stimulation
Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.
Brain Mapping
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
Phenylthiohydantoin
Thiohydantoin benzene derivative.
Sterol Esterase
An enzyme that catalyzes the hydrolysis of CHOLESTEROL ESTERS and some other sterol esters, to liberate cholesterol plus a fatty acid anion.
Ethical Review
A formal process of examination of patient care or research proposals for conformity with ethical standards. The review is usually conducted by an organized clinical or research ethics committee (CLINICAL ETHICS COMMITTEES or RESEARCH ETHICS COMMITTEES), sometimes by a subset of such a committee, an ad hoc group, or an individual ethicist (ETHICISTS).
Drug Industry
That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.
Ethics Committees, Research
Hospital or other institutional committees established to protect the welfare of research subjects. Federal regulations (the "Common Rule" (45 CFR 46)) mandate the use of these committees to monitor federally-funded biomedical and behavioral research involving human subjects.
Hypopituitarism
Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.
Androstenols
Unsaturated androstanes which are substituted with one or more hydroxyl groups in any position in the ring system.
Newspapers
Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)
Bone Density Conservation Agents
Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES such as OSTEOPOROSIS.
Mass Media
Instruments or technological means of communication that reach large numbers of people with a common message: press, radio, television, etc.

A multicomponent intervention to prevent delirium in hospitalized older patients. (1/2588)

BACKGROUND: Since in hospitalized older patients delirium is associated with poor outcomes, we evaluated the effectiveness of a multicomponent strategy for the prevention of delirium. METHODS: We studied 852 patients 70 years of age or older who had been admitted to the general-medicine service at a teaching hospital. Patients from one intervention unit and two usual-care units were enrolled by means of a prospective matching strategy. The intervention consisted of standardized protocols for the management of six risk factors for delirium: cognitive impairment, sleep deprivation, immobility, visual impairment, hearing impairment, and dehydration. Delirium, the primary outcome, was assessed daily until discharge. RESULTS: Delirium developed in 9.9 percent of the intervention group as compared with 15.0 percent of the usual-care group, (matched odds ratio, 0.60; 95 percent confidence interval, 0.39 to 0.92). The total number of days with delirium (105 vs. 161, P=0.02) and the total number of episodes (62 vs. 90, P=0.03) were significantly lower in the intervention group. However, the severity of delirium and recurrence rates were not significantly different. The overall rate of adherence to the intervention was 87 percent, and the total number of targeted risk factors per patient was significantly reduced. Intervention was associated with significant improvement in the degree of cognitive impairment among patients with cognitive impairment at admission and a reduction in the rate of use of sleep medications among all patients. Among the other risk factors per patient there were trends toward improvement in immobility, visual impairment, and hearing impairment. CONCLUSIONS: The risk-factor intervention strategy that we studied resulted in significant reductions in the number and duration of episodes of delirium in hospitalized older patients. The intervention had no significant effect on the severity of delirium or on recurrence rates; this finding suggests that primary prevention of delirium is probably the most effective treatment strategy.  (+info)

Can we cure indolent lymphomas? (2/2588)

The current consensus is that indolent lymphomas are incurable disorders. There are some indications that these malignancies are potentially curable. Indeed, not all indolent lymphomas are currently incurable. For example, patients with Ann Arbor stage I-II indolent lymphomas can experience long-term disease-free survival and probable cure. Also, from the available literature data, it seems that the achievement of a molecular complete remission is a desirable objective. Patients who achieve a persistently negative PCR state seldom relapse, whereas the opposite is true for persistently positive cases. In view of its excellent correlation with disease-free survival when examined serially in multiple blood or marrow samples, the PCR technique has the potential of providing a tumor marker that can be used as an early end point for clinical trials. By serving as an early surrogate end point, PCR could play an important role in expediting the development of new treatment strategies. Whether IFN is capable of increasing the molecular complete remission rate as measured by PCR is not known. However, it is clear that from the clinical standpoint, IFN has been able to increase 2-fold the length of remission in patients with advanced indolent lymphomas. In at least two studies, this has been associated with prolongation of survival. More intensive regimens such as alternating triple therapy, when used in combination with IFN, seem to have improved the quality of remissions as judged by the PCR assay. Finally, the site where the bcl-2 breakpoint occurs seems to have clinical significance. Those follicular lymphomas with germ-line bcl-2, in our experience, have behaved more aggressively than the others, and their failure-free survival seems different from the usual indolent lymphomas and more closely resembles the large cell lymphomas. Although the biological significance of this observation is not yet understood, this group might actually constitute a prognostically different subset with a more aggressive and perhaps more curable lymphoma. Whether the plateau observed in their failure-free survival curve will be maintained with more follow-up and whether they might be a curable subset remain to be determined.  (+info)

Low-molecular-weight heparin in outpatient treatment of DVT. (3/2588)

Patients with a diagnosis of acute deep venous thrombosis have traditionally been hospitalized and treated with unfractionated heparin followed by oral anticoagulation therapy. Several clinical trials have shown that low-molecular-weight heparin is at least as safe and effective as unfractionated heparin in the treatment of uncomplicated deep venous thrombosis. The use of low-molecular-weight heparin in an outpatient program for the management of deep venous thrombosis provides a treatment alternative to hospitalization in selected patients. Use of low-molecular-weight heparin on an outpatient basis requires coordination of care, laboratory monitoring, and patient education and participation in treatment. Overlapping the initiation of warfarin permits long-term anticoagulation. Advantages include a decreased incidence of heparin-induced thrombocytopenia and fewer episodes of bleeding complications. Future clinical trials evaluating the safety and efficacy of low-molecular-weight heparin in the treatment of complicated deep venous thrombosis will further define appropriate indications for use and strategies for outpatient management.  (+info)

Time course of respiratory decompensation in chronic obstructive pulmonary disease: a prospective, double-blind study of peak flow changes prior to emergency department visits. (4/2588)

The aim of this study was to look at changes in peak expiratory flow rates (PEFR) prior to emergency department visits for decompensated chronic obstructive pulmonary disease (COPD). It was designed as a prospective, double-blind study at the Albuquerque Veterans Affairs Medical Center. Twelve patients with an irreversible component of airflow obstruction on pulmonary function tests were assessed. At entry, all subjects were instructed in the use of a mini-Wright peak flow meter with electronic data storage. They then entered a 6-month monitoring phase in which they recorded PEFR twice daily, before and after bronchodilators. The meter displays were disabled so that the patients and their physicians were blinded to all values. Medical care was provided in the customary manner. Patients were considered to have respiratory decompensation if they required treatment for airflow obstruction in the Emergency Department (ED) and no other causes of dyspnea could be identified. Simple linear regression was used to model changes in PEFR over time. The 12 subjects had 22 episodes of respiratory decompensation during 1741 patient-days of observation. Two episodes could not be analysed because of missing values. Ten episodes in seven subjects were characterized by a significant linear decline in at least one peak flow parameter prior to presentation. The mean rates of change for the four daily parameters varied from 0.22% to 0.27% predicted per day (or 1.19 to 1.44 1 min-1 day-1). The average decrement in these parameters ranged from 30.0 to 33.8 1 min-1 (or 18.6%-25.9% of their baseline values). No temporal trends were found for the 10 episodes occurring in the other five subjects. We concluded that respiratory decompensation is characterized by a gradual decline in PEFR in about half of cases. Future studies should be done to elucidate the mechanisms of respiratory distress in the other cases.  (+info)

Enhancing the identification of excessive drinkers on medical wards: a 1-year follow-up study. (5/2588)

This paper describes a 1-year follow-up study examining whether hospital ward doctors and nurses continue to take quantitative alcohol histories and provide brief intervention to problem drinkers on general medical wards after the introduction of a simple protocol. Regular training in the use of this protocol was stipulated in the annual service contract between the Health Authority and the Hospital Trusts. Improvements in staff practice persisted at 1-year follow-up, although it fell from a peak at an earlier phase of the study. The positive role of state purchasers of health services in sustaining improvements in clinical practice is discussed.  (+info)

Agreeing criteria for audit of the management of induced abortion: an approach by national consensus survey. (6/2588)

OBJECTIVE: To obtain a national consensus view of suggested criteria for good quality care in induced abortion to serve as a basis for standards for audit to assess current clinical practice. DESIGN: Postal, questionnaire survey assessing consensus agreement with criteria identified from a literature review and refined by an invited panel of four gynaecologists and the gynaecology audit project in Scotland (GAPS) committee. SETTING: Scotland. SUBJECTS: All 132 practising consultant gynaecologists. MAIN MEASURES: Overall level of agreement with each of 20 suggested audit criteria. RESULTS: 121 completed questionnaires were received (response rate 92%), of which 119 were returned in time for analysis; 107 came from consultants who practised abortion routinely and were included in the analysis. Nineteen of 20 suggested criteria were validated by an overall balance of agreement. The most strongly supported criterion (agreement score +93) was for ascertaining rhesus status of the woman and prophylaxis after abortion, if indicated. The only criterion to elicit a negative agreement score (-27) was that dilatation and evacuation is the best method of abortion at 12-15 weeks' gestation. The ranked and prioritised criteria resulting from this exercise are being used within a national audit project. CONCLUSIONS: A postal questionnaire survey among interested clinicians resulted in a good response rate and enabled the audit criteria to be validated and ranked more objectively and among more clinicians, than would have been possible by group discussion.  (+info)

Audit of thrombolysis initiated in an accident and emergency department. (7/2588)

Early thrombolytic therapy after acute myocardial infarction is important in reducing mortality. To evaluate a system for reducing in-hospital delays to thrombolysis pain to needle and door to needle times to thrombolysis were audited in a major accident and emergency (A and E) department of a district general hospital and its coronary care unit (CCU), situated about 5 km away. Baseline performance over six months was assessed retrospectively from notes of 43 consecutive patients (group 1) transferred to the CCU before receiving thrombolysis. Subsequently, selected patients (23) were allowed to receive thrombolysis in the A and E department before transfer to the CCU. The agent was administered by medical staff in the department after receiving oral confirmation of myocardial infarction from the admitting medical officer in the CCU on receipt of fax transmission of the electrocardiogram. A second prospective audit during six months from the start of the new procedure established time intervals in 23 patients eligible to receive thrombolysis in the A and E department (group 2b) and 30 ineligible patients who received thrombolysis in the CCU (group 2a). The groups did not differ significantly in case mix, pre-hospital delay, or transfer time to the CCU. In group 2b door to needle time and pain to needle time were reduced significantly (geometric mean 38 min v 121 min (group 2a) and 128 min (group 1); 141 min v 237 min (group 2a) and 242 min (group 1) respectively, both p < 0.0001). The incidence of adverse effects was not significantly different. Nine deaths occurred (six in group 1, three in group 2b), an in-hospital mortality of 9.9%. Thrombolysis can be safely instituted in the A and E department in selected patients, significantly reducing delay to treatment.  (+info)

Improving quality through cost recovery in Niger. (8/2588)

New evidence on the quality of health care from public services in Niger is discussed in terms of the relationships between quality, costs, cost-effectiveness and financing. Although structural attributes of quality appeared to improve with the pilot project in Niger, significant gaps in the implementation of diagnostic and treatment protocols were observed, particularly in monitoring vital signs, diagnostic examination and provider-patient communications. Quality improvements required significant investments in both fixed and variable costs; however, many of these costs were basic input requirements for operation. It is likely that optimal cost-effectiveness of services was not achieved because of the noted deficiencies in quality. In the test district of Boboye, the revenues from the copayments alone covered about 34% of the costs of medicines or about 20% of costs of drugs and administration. In Say, user fees covered about 50-55% of the costs of medicines or 35-40% of the amount spent on medicines and cost-recovery administration. In Boboye, taxes plus the additional copayments covered 120-180% of the cost of medicines, or 75-105% of the cost of medicines plus administration of cost recovery. Decentralized management and legal conditions in the pilot districts appeared to provide the necessary structure to ensure that the revenues and taxes collected would be channelled to pay for quality improvements.  (+info)

SYSTEMS AND METHODS FOR CLINICAL PROTOCOL DEVELOPMENT - Patent applicationSYSTEMS AND METHODS FOR CLINICAL PROTOCOL DEVELOPMENT - Patent application
0113] Although it is shown by way of example that a browser program (e.g. 1215) may be used to access a protocol builder system by users to perform functions for developing drug protocols, it should be appreciated that other program types may be used to interface a user to server process 1213 or a protocol builder system. For instance, an application program 1214 that is specially-developed to manage drug protocol development may be provided to permit a user to participate in a project, answer challenge questions, etc., according to various embodiments of the present invention. A client program may be, for example, a thin client including an interface for submitting and monitoring challenge questions, and/or drug protocol development projects. Alternatively, the client may be a scripted program, or any other type of program having the capability of transferring data. According to one embodiment, such client programs may, for example, be downloaded and installed over the network. Further, these ...
http://www.patentsencyclopedia.com/app/20130132112
A method for discovering and inferring appropriate eligibility criteria in clinical trial protocols without labeled data | BMC...A method for discovering and inferring appropriate eligibility criteria in clinical trial protocols without labeled data | BMC...
Given a potentially huge set of candidate criteria, our goal is to help users choose the most appropriate criteria from among the candidates. In this work, we assume that the candidate criteria exist in some document(s) in a given repository, either separately from different documents or together in the same document, and our technical objective is to rank these candidates according to their appropriateness to the task at hand. As mentioned previously, such task would be to put together a clinical trial protocol about some particular disease, treatment, or drug.. To provide a concrete idea of our problem, the following is a snippet of a clinical trial protocol, downloaded from the clinical trials website http://www.clinicaltrials.gov, and modified for presentation as an example. It shows the title, the objective of the clinical trial as well as the inclusion and exclusion criteria.. Title: Antioxidant Systems and Age-Related Macular Degeneration Objective:. The objective of this study is to ...
https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/1472-6947-13-S1-S6
Clinical Protocols in Obstetrics and Gynecology, 3rd Edition - ایران تکست بوکClinical Protocols in Obstetrics and Gynecology, 3rd Edition - ایران تکست بوک
By (author): John E. Turrentine. Expanded and updated, the new edition of the bestselling Clinical Protocols in Obstetrics and Gynecology is the definitive quick-reference for use in office practice and hospital settings. With information drawn from ACOG technical bulletins, OB/GYN publications, articles, textbooks, computer sources, and the authors vast personal experience, outlines of more than 400 clinical protocols help ensure that everyone on the team is on the same page.. Flowcharts and algorithms make common problems seem simpler. Tables and decision trees make the information easy to refer to when running from room to room during a busy day in the office or hospital. This complete, up-to-date coverage makes Clinical Protocols in Obstetrics and Gynecology, Third Edition the best available study guide for board certification and a complete reference for busy obstetricians and gynecologists ...
http://irantextbook.ir/2146-clinical-protocols-in-obstetrics-and-gynecology-3rd-edition.html
ABM clinical protocol #1: guidelines for blood glucose monitoring and treatment of hypoglycemia in term and late-preterm...ABM clinical protocol #1: guidelines for blood glucose monitoring and treatment of hypoglycemia in term and late-preterm...
A central goal of The Academy of Breastfeeding Medicine is the development of clinical protocols for managing common medical problems that may impact breastfeeding success. These protocols serve only as guidelines for the care of breastfeeding mothers and infants and do not delineate an exclusive co …
https://pubmed.ncbi.nlm.nih.gov/24823918/?dopt=Abstract
Digging into the Moderna Vaccine Clinical Trials Protocols and Results | Richard Jaffe, Esq.Digging into the Moderna Vaccine Clinical Trials Protocols and Results | Richard Jaffe, Esq.
Moderna has just announced that its RNA based vaccine is starting a phase 3 clinical trial with 30,000 subjects, so I thought it might be useful to take a look at the publicly available information about the trial, and how they got there. Lets go logically and chronologically and start with the phase 1 safety study. The Phase 1 study A phase 1 study is a safety study. They usually have relatively few subjects, and different doses are given because dosing in terms of side effects is usually an important endpoint in a safety study. Here is the Brief Summary of the Phase 1 study published by Moderna Brief Summary: This is a phase I, open-label, dose-ranging clinical trial in males and non-pregnant females, starting at 18 years of age, inclusive, who are in good health and meet all eligibility criteria. This clinical trial is designed to assess the safety, reactogenicity, and immunogenicity of mRNA-1273 manufactured by ModernaTX, Inc. mRNA-1273 is a novel lipid nanoparticle (LNP)-encapsulated mRNA-based
https://rickjaffeesq.com/2020/07/28/digging-into-the-moderna-vaccine-clinical-trials-protocols-and-results/?replytocom=21876
Three approaches to glucose monitoring in non-insulin treated diabetes: a pragmatic randomized clinical trial protocol | BMC...Three approaches to glucose monitoring in non-insulin treated diabetes: a pragmatic randomized clinical trial protocol | BMC...
Self-monitoring of blood glucose in patients with diabetes has traditionally been considered to be a pillar of diabetes self-care. Scientific examinations of SMBG in T2DM have provided mixed results. An early epidemiological evaluation of the issue using a retrospective, longitudinal analysis showed that nonfatal micro- and macrovascular event rates along with fatal event rates were lower in individuals performing SMBG routinely as compared to those who were not [3]. A multitude of clinical trials followed. Several showed a significant benefit from SMBG testing on improving glycemic control [4-7], while others found no evidence of benefit [16]. In fact, some studies even suggested harm from routine SMBG in patients with T2DM, specifically, higher rates of depression and increased cost without accompanying benefits [31].. Given these mixed results, a series of meta-analyses and systematic reviews were conducted to investigate the benefit or lack thereof of SMBG on glycemic lowering in patients ...
http://bmchealthservres.biomedcentral.com.preview-live.oscarjournals.springer.com/articles/10.1186/s12913-017-2202-7
Use of an accelerated chest pain assessment protocol in patients at intermediate risk of adverse cardiac events | The Medical...Use of an accelerated chest pain assessment protocol in patients at intermediate risk of adverse cardiac events | The Medical...
Discussion. We found that ACPAP simplified and facilitated the effective management of patients at intermediate risk of adverse cardiac events at our hospital. Two-thirds of patients assessed with ACPAP were reclassified as low risk and discharged early a mean of 14 hours after presentation, allowing early return to work and normal activities; 1% of these patients had cardiac events (all elective revascularisations) by six-month follow-up, compared with 19% of high-risk patients. We have identified no missed AMIs since adopting the protocol. However, a low rate of missed AMI depends on the willingness of emergency staff to enrol patients with both typical and atypical symptoms in the protocol, particularly the elderly and those with diabetes, whose presentations are often atypical or even silent.. A limitation of the study was that it was a clinical audit and not a prospective controlled trial of differing strategies in managing chest pain. However, although observational, our study had ...
https://www.mja.com.au/journal/2003/178/8/use-accelerated-chest-pain-assessment-protocol-patients-intermediate-risk
Abdominal Exam IV: Acute Abdominal Pain Assessment | Protocol (Translated to German)Abdominal Exam IV: Acute Abdominal Pain Assessment | Protocol (Translated to German)
JoVE publishes peer-reviewed scientific video protocols to accelerate biological, medical, chemical and physical research. Watch our scientific video articles.
https://www.jove.com/v/10120/abdominal-prfung-iv-akute-bauchschmerzen-bewertung?language=German
Rapid Health Assessment Protocols for Emergencies - 1 - PreparednessRapid Health Assessment Protocols for Emergencies - 1 - Preparedness
if the rapid assessment is to be useful for guiding emergency health response, it must be clear in advance which individuals make the decisions on emergency interventions because they must receive the information and recommendations made
http://healthlibrary.com/book51_chapter682.htm
Protocol Development and Regulatory SupportProtocol Development and Regulatory Support
When you express interest in a specific study, the information from your profile will be sent to the doctor conducting that study. If youre eligible to participate, you may be contacted by a nurse or study coordinator. If you select a health category rather than a specific study, doctors who have active studies in that area may contact you to ask if you would like to participate. In both cases, you will be contacted by the preferred method (email or phone) that you specified in your profile. ...
http://ycci.yale.edu/researchers/ors/protocol.aspx
WHO/Europe | 2013 Revision - Protocol 4. Management of tuberculosis and HIV coinfectionWHO/Europe | 2013 Revision - Protocol 4. Management of tuberculosis and HIV coinfection
The WHO Regional Office for Europe is revising five clinical protocols on treatment of and care for people with HIV and AIDS, which were part of the 13 protocols set combined in one volume in 2007.. The protocols are the cornerstone of the strategic actions that WHO has taken as part of its contribution to ensure universal access to treatment and care for people living with HIV and to comprehensively address their health problems, including preventing and treating co-infections and co-morbidities - one of the six priority areas of the European Action Plan for HIV/AIDS 2012-2015.. Addressing the diverse capacity of the countries in the WHO European Region to implement recommendations, the revised protocols provide preferable, alternative and acceptable options which allow countries to choose appropriate recommendations depending on the available resources. Five revised clinical protocols are envisaged for publication this year.. ...
http://www.euro.who.int/en/health-topics/communicable-diseases/hivaids/publications/2012/hivaids-treatment-and-care.-clinical-protocols-for-the-who-european-region.-2012-revisions/2013-revision-protocol-4.-management-of-tuberculosis-and-hiv-coinfection
At a Glance - Updated CME INDIA COVID Management Protocol 2021 - CME INDIAAt a Glance - Updated CME INDIA COVID Management Protocol 2021 - CME INDIA
Updated COVID-19 Management Protocol 2021 from CME INDIA now available in a summarized form. Read the new guidelines to better manage COVID.
https://cmeindia.in/at-a-glance-updated-cme-india-covid-management-protocol-2021/
All recomendationsAll recomendations
The condition of effectiveness is not fully fulfilled - the new unified clinical protocol was developed based on evidentiary medicine, however the focus is made on the compliance with clinical efficacy without due consideration of the economic aspect. For example, in cases when resistance profile is not known (for a term of 2 months), it is economically more advantageous to start treatment with more expensive and more effective treatment regimen, as not only the cost of medication should be accounted but the cost of a patients stay in a hospital as well (which includes not only material costs but also psychological challenge for a patient to be apart from his/her usual social environment for a long time). Another example: according with WHO recommendations, for diagnosis with molecular DNA tests, there should be developed extended criteria regarding the patients who must undergo such tests; however, such criteria in the applicable unified clinical protocol are essentially restricted (article ...
http://stoptb.in.ua/en/all-recommendations
Best Practices in Evaluating Novel Biomarker Fit for Purpose and Translatability<...Best Practices in Evaluating Novel Biomarker Fit for Purpose and Translatability<...
TY - CHAP. T1 - Best Practices in Evaluating Novel Biomarker Fit for Purpose and Translatability. AU - Baker, Amanda F. PY - 2016/1/1. Y1 - 2016/1/1. N2 - This chapter discusses various tactical aspects to consider when evaluating novel biomarker translatability. The evaluation procedures warrant careful attention in order to leverage the most appropriate traditional and novel biomarkers in the relevant biological matrices. Integration of biomarkers into clinical protocols requires incorporation of biomarker analysis into one of the study objectives. The chapter also describes the use of fit-for-purpose biomarkers in different phases of drug development. When translating a biomarker from preclinical to clinical studies, the species specificity of the assay should be evaluated. Evidence-based protocols for sample collection should be developed and implemented for each biomarker analyzed. When multiple biomarkers are to be analyzed, multiple types of collection containers/tubes may be necessary. ...
https://arizona.pure.elsevier.com/en/publications/best-practices-in-evaluating-novel-biomarker-fit-for-purpose-and-
Provision of services for the treatment of bronchial asthmaProvision of services for the treatment of bronchial asthma
Dear colleagues and visitors to our site! Entered into force Clinical Protocol for the diagnosis and treatment of tuberculosis (adult and pediatric population), which you can find on our website in the section Organizational and methodological work -, Legal acts on service. Dear colleagues and visitors to our site! Entered into force Clinical Protocol for the diagnosis and treatment of tuberculosis (adult and pediatric population), which you can find on our website in the section Organizational and methodological work -, Legal acts on .... Readmore ...
http://rnpcpf.by/en/news/167-2015-11-06-09-37-31.html
Evidence-based Implant Treatment Planning and Clinical Protocols PDF - Am-MedicineEvidence-based Implant Treatment Planning and Clinical Protocols PDF - Am-Medicine
This Website Provides Over 10000 Free Medical Books and more for all Students and Doctors This Website the best choice for medical students during and after learning medicine.
http://am-medicine.com/2017/08/evidence-based-implant-treatment-planning-and-clinical-protocols.html
CCCTG - Standard Operating Procedures Clinical Protocol Ie: Cerebrospinal Fluid Sample Collection - PLATELETCCCTG - Standard Operating Procedures Clinical Protocol Ie: Cerebrospinal Fluid Sample Collection - PLATELET
Special Note 1.2: Processing and handling of CSF for analysis - please remember endotoxin is ubiquitous and can change expression of all mediators being assayed. Endotoxin free precautions should be taken for handling of all procedures (sterile precautions and using endotoxin free solutions should suffice ...
https://ccctg.ca/CCCTBG/SOP-I-e-CSF-Collection.aspx
CORRECTING and REPLACING -- Celsion Files Immunotherapy Clinical Protocol for the Evaluation of GEN-1 to Treat Newly Diagnosed...CORRECTING and REPLACING -- Celsion Files Immunotherapy Clinical Protocol for the Evaluation of GEN-1 to Treat Newly Diagnosed...
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http://investor.celsion.com/releasedetail.cfm?ReleaseID=1048566
Essentials of Clinical Research | Department of Epidemiology & Population Health | Stanford MedicineEssentials of Clinical Research | Department of Epidemiology & Population Health | Stanford Medicine
The Essentials of Clinical Research course is designed for faculty and staff engaged in clinical research at Stanford and will consist of 10 sessions. The course introduces attendees to basic principles of clinical research design, including biostatistics; design and interpretation of diagnostic and predictive test studies; required and desired elements of clinical trial protocols. The course will also introduce regulatory aspects of clinical research conduct and oversight, Good Clinical Practice (GCP), and ethical dimensions of clinical research.. Sessions are held on Thursdays from 3:30 - 5:30 pm beginning January 9 through March 12, 2020.. For more information regarding course content, instructors, and logistics download the course syllabus:. ...
https://med.stanford.edu/epidemiology-dept/education/essentials-of-clinical-research.html
286390876 Profile | BrightOwl286390876 Profile | BrightOwl
Analyze data Analytical skills Control data Develop clinical trial protocols Develop protocols Guide students Interact with nurses Interact with physicians Interpret data Monitor a clinical study Report data Search literature on clinical trials Write papers Write protocolsAdjust processes and methodsassess the needs of the project(s)/program(s) and make changes in process, work flow and/or assignments.Assign activitiesAssist with experimentsAssist with proceduresAttend at steering committee meetingsAttend investigator meetingAttend seminarsAttend seminars, courses and meetings within and outside the companyCalculate timelines for conducting and completing the trialClinical data collectionCoachcollaborate in research projects at universitiesCollaborate with medical teamCollaborate with principal investigatorCollaborate with project teamCollect dataCommunicate with investigatorCommunicate with sponsorConduct animal studiesConduct literature searchesConduct research at universitiesConduct ...
https://brightowl.pro/company/expert/profile/postdoctoral-research-fellow-286390876
Strategic Feasibility Research Analyst I (Office-Based) - IQVIA Biotech - IQVIA | Morrisville, NCStrategic Feasibility Research Analyst I (Office-Based) - IQVIA Biotech - IQVIA | Morrisville, NC
Investigates the clinical subject area provided in the sponsors RFP in order to define the scope of the clinical trial; Researches pertinent scientific/clinical information that may include, but is not limited to: disease background (etiology, epidemiology, statistical information, symptoms, and methods of diagnosis), current standards of care (treatments methods), how the sponsor-proposed intervention fits into the current treatment landscape, and information regarding competing therapeutics in clinical development. This information is augmented with a critical evaluation of the clinical trial protocol and supporting documents, to proactively identify study strengths and potential pitfalls ...
https://www.simplyhired.com/job/i97oM1gfEK5XAjmy3-Yunnm7_4GhSzvuDT-sNi9m-hq1bmLzuxylUA?q=iqvia
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There are many reasons why clinical trials dont work well. A major one is not making them useful or interesting to patients. I had high hopes when I heard about the recent clinical trial protocol (plan) template from the U.S. Food & Drug Administration (FDA) and the National Institutes of Health (NIH) Joint Leadership Council (JLC). Unfortunately, it looks like they…
https://collyar.wordpress.com/2016/04/17/make-clinical-trials-better-for-patients/
Plus itPlus it
This study suggests that, compared with conventional management, a treatment programme for failure to thrive delivered by health visitors using strict diagnostic criteria and assessment protocols, with limited additional support, results in a weight gain of around half an intercentile space using UK charts, equivalent to about 550 g. This was despite only just over half of the intervention group receiving the full programme, because a fifth showed prior spontaneous recovery and another quarter exercised their right to decline aspects of the programme. The fairly low levels of compliance with the follow up home visit were also disappointing, but compliance rates were similar in both arms, and those interviewed were representative of the original group. It is fortunate, however, that routine follow up weights were also retrieved for a high proportion of the group, which also showed a significant treatment benefit.. The severity of failure to thrive found in this cohort was similar to previous ...
http://www.bmj.com/content/317/7158/571
Electronic meal ordering systems - Sax Institute - Sax InstituteElectronic meal ordering systems - Sax Institute - Sax Institute
May 2015. Prgomet M, Li L, Li J, Georgiou A, Westbrook J. This Evidence Check report presents findings from an evidence scan of the Australian and international literature on electronic meal ordering system reforms and their impacts on hospital and patient outcomes.. The report describes different types of electronic meal ordering systems and related food service reforms, and nutritional screening and risk assessment protocols implemented alongside these. It presents evidence of the impact of electronic meal ordering systems on patient outcomes and on staff, and discusses considerations for future evaluations of electronic meal ordering systems.. ...
https://www.saxinstitute.org.au/publications/evidence-check-library/electronic-meal-ordering-systems/
Lori Goldman, LAC | Counselor / Therapist in Princeton Junction, NJ 08550Lori Goldman, LAC | Counselor / Therapist in Princeton Junction, NJ 08550
Licensed Associate Counselor | Portrait Health Centers are multi-specialty clinics that employ the most cutting-edge and proven assessment protocols and treatment options available, believing that an Effective Treatment Depends On An Accurate Diagnosis. Individuals should not have to
https://therapynext.com/ProfileMobile/lorigoldman
Denine Hasan, LPC | Licensed Professional Counselor in Freehold, NJ 07728Denine Hasan, LPC | Licensed Professional Counselor in Freehold, NJ 07728
Licensed Professional Counselor | Substance Abuse Coordinator | Portrait Health Centers are multi-specialty clinics that employ the most cutting-edge and proven assessment protocols and treatment options available, believing that an Effective Treatment Depends On An Accurate Diagnosis. Individuals should not have to
https://therapynext.com/ProfileMobile/deninehasan
Datasets - TRCA Open DataDatasets - TRCA Open Data
In order to assess the Degradation of Aesthetics BUI for the Toronto and Region AOC, an assessment protocol was developed that utilized existing monitoring programs and local ...
https://data.trca.ca/dataset?tags=Monitoring&tags=TRCA&res_format=Esri+REST
EFSA Journal | Autorité européenne de sécurité des alimentsEFSA Journal | Autorité européenne de sécurité des aliments
EFSA Journal | Autorité européenne de sécurité des alimentsEFSA Journal | Autorité européenne de sécurité des aliments
Prior to being applied to the new bisphenol A (BPA) re‐evaluation, the study appraisal methodology described in the 2017 BPA hazard assessment protocol, i.e. the so‐called 2017 methodology, was tested on a selection of studies that had been previously a .... ...
http://www.efsa.europa.eu/fr/publications/?results_per_page=20&f%5B0%5D=im_field_subject%3A61721&f%5B1%5D=im_field_subject%3A61866&f%5B2%5D=im_field_subject%3A61786&f%5B3%5D=im_field_subject%3A61826&f%5B4%5D=im_field_subject%3A70354&f%5B5%5D=im_field_subject%3A70339
Child of Trans Labs | ICTRChild of Trans Labs | ICTR
The Imaging Translational Technology Core (Imaging TTC) facilitates one-on-one consultation with imaging experts for study design, imaging protocol development and study implementation. The core facilitates integrated use of imaging resources in translational projects and clinical trials and offers research imaging management infrastructure through the Johns Hopkins Medical Image Research Archive Center for research data storage and distribution Imaging also offers CORIS, a one week observership program for anyone interested in radiology. Participants have an opportunity to shadow Katarzyna (Kasia) J. Macura, MD, PhD, FACR, Professor of Radiology, Urology and Oncology. For more information and to schedule a time, contact Atefeh Ameri at … Continue reading →. ...
https://ictr.johnshopkins.edu/category/child-of-trans-labs/
Plus itPlus it
It is well accepted that the clinical features of patients with HPV-driven HNSCC are distinct from those of patients with HPV-negative disease. These include distinct sites of origin of the disease (e.g., tonsil and base of tongue), younger age, and improved relapse-free survival following initial definitive treatment. Clinically, an emphasis on protocol development for patients with HPV-driven HNSCCs has consisted largely of de-escalation of standard therapy with a lower dose of radiation, more limited resection, or deintensification of chemotherapy.. Initial NGS studies of HPV-positive patients confirmed that these individuals harbor few genomic alterations in TP53 and/or CDKN2A, presumably due to the activity of the HPV E6 and E7 viral oncoproteins (11). These studies also suggested that HPV-driven HNSCCs display less genomic complexity as compared with HPV-negative disease, though TCGA and other more recent cohorts did not confirm this finding, perhaps due to tobacco use in the HPV-positive ...
http://cancerdiscovery.aacrjournals.org/content/5/3/239
Treatment Protocols | Million Hearts®Treatment Protocols | Million Hearts®
Find standardized, evidence-based protocols for cholesterol management, tobacco cessation, and hypertension treatment to use in your practice.
https://millionhearts.hhs.gov/tools-protocols/protocols.html
Http11AprProtocol (Apache Tomcat 8.5.59 API Documentation)Http11AprProtocol (Apache Tomcat 8.5.59 API Documentation)
Abstract the protocol implementation, including threading, etc. Processor is single threaded and specific to stream-based protocols, will not fit Jk protocols like JNI ...
https://tomcat.apache.org/tomcat-8.5-doc/api/org/apache/coyote/http11/Http11AprProtocol.html
AjpAprProtocol (Apache Tomcat 7.0.106 API Documentation)AjpAprProtocol (Apache Tomcat 7.0.106 API Documentation)
Abstract the protocol implementation, including threading, etc. Processor is single threaded and specific to stream-based protocols, will not fit Jk protocols like JNI ...
https://tomcat.apache.org/tomcat-7.0-doc/api/org/apache/coyote/ajp/AjpAprProtocol.html
SP 800-52 Rev. 2, Guidelines for TLS Implementations | CSRCSP 800-52 Rev. 2, Guidelines for TLS Implementations | CSRC
Transport Layer Security (TLS) provides mechanisms to protect data during electronic dissemination across the Internet. This Special Publication provides guidance to the selection and configuration of TLS protocol implementations while making effective use of Federal Information Processing Standards (FIPS) and NIST-recommended cryptographic algorithms. It requires that TLS 1.2 configured with FIPS-based cipher suites be supported by all government TLS servers and clients and requires support for TLS 1.3 by January 1, 2024. This Special Publication also provides guidance on certificates and TLS extensions that impact security. ...
https://csrc.nist.gov/publications/detail/sp/800-52/rev-2/final
Ivermectin not to be included in Centres coronavirus management protocol - india news - Hindustan TimesIvermectin not to be included in Centres coronavirus management protocol - india news - Hindustan Times
The experts of ICMRs National Task Force for Covid-19 and the Joint Monitoring Group held its meeting on Thursday to deliberate on whether the drug should be included in the national treatment guidelines
https://www.hindustantimes.com/india-news/ivermectin-not-to-be-included-in-centre-s-coronavirus-management-protocol/story-H2ahRiDO3nvCqktOBJGPjP.html
Difference between revisions of EBQ:ProCESS Trial - WikEMDifference between revisions of EBQ:ProCESS Trial - WikEM
This multicenter randomized trial assigned patients 1341 patients to protocol EGDT (Early Goal Directed Therapy), protocol-based standard therapy that did not require the placement of a central venous catheter, administration of inotropes, or blood transfusions or usual care which was not standardized. The data was analyzed with intention to treat to determine in protocolized treatment of sepsis had a mortality benefit as was shown in the original Rivers Trial. No significant 60 or 90 day mortality benefit was found to the protocol therapy and greater hospital resources such as ICU admissions were found in the protocol based groups. ...
https://www.wikem.org/w/index.php?title=EBQ:ProCESS_Trial&diff=prev&oldid=18527
IJERPH | Free Full-Text | Measuring Quality Gaps in TB Screening in South Africa Using Standardised Patient Analysis | HTMLIJERPH | Free Full-Text | Measuring Quality Gaps in TB Screening in South Africa Using Standardised Patient Analysis | HTML
This is the first multi-district Standardised Patient (SP) study in South Africa. It measures the quality of TB screening at primary healthcare (PHC) facilities. We hypothesise that TB screening protocols and best practices are poorly adhered to at the PHC level. The SP method allows researchers to observe how healthcare providers identify, test and advise presumptive TB patients, and whether this aligns with clinical protocols and best practice. The study was conducted at PHC facilities in two provinces and 143 interactions at 39 facilities were analysed. Only 43% of interactions resulted in SPs receiving a TB sputum test and being offered an HIV test. TB sputum tests were conducted routinely (84%) while HIV tests were offered less frequently (47%). Nurses frequently neglected to ask SPs whether their household contacts had confirmed TB (54%). Antibiotics were prescribed without taking temperatures in 8% of cases. The importance of returning to the facility to receive TB test results was only explained
https://www.mdpi.com/1660-4601/15/4/729/htm
help! | allnurseshelp! | allnurses
Hi, Currently in middle of third year nursing essay. Anyone have any idea where to get a definition of clinical protocols and standards - really stuck! Cheers Trigger x
http://allnurses.com/general-nursing-student/help-15099.html
RTMP White Papers - BitpipeRTMP White Papers - Bitpipe
Read a description of RTMP. This is also known as Routing Table Protocols, Routing Table Management Protocol, Routing Table Maintenance Protocol. Free detailed reports on RTMP are also available.
https://www.bitpipe.com/rlist/term/type/white+paper/RTMP.html
New protocols - ANONYMOUS-ASTHMANew protocols - ANONYMOUS-ASTHMA
I had a wee meeting to finalise my anticipatory care plan for when I need to go into hospital. It was really good which is hopefully going to change quite a lot. I was nervous as this consultant is new and I have not known him long but I didnt need to worry. He was…
https://anonymousasthma.me/2015/03/01/new-protocols/
Protocol 1000 - MMS Wiki | Jim Humble | Genesis 2 Church | MMSWiKi.isProtocol 1000 - MMS Wiki | Jim Humble | Genesis 2 Church | MMSWiKi.is
The instructions given here are for the original, and what I like to call, Classic Protocol 1000. If you do further research you will find that we and many other people have tried various versions of Protocol 1000 over the years. While most all of the slight variations of Protocol 1000 have been successful, according to reports we have received from around the world the success has never been as good as the original protocol of mixing the dose fresh every hour. Protocol 1000 is taking a maximum of 3 drops of activated MMS (MMS1) in 4 ounces/120 ml of water once each hour, for eight consecutive hours, every day, for three weeks or until well. Do not start out at 3 drops an hour. Try to build up to 3 drops slowly. If your body does not tolerate an increase of drops, stick with what works best for you. Your health may be recovered taking less than 3 drops in each dose. Some people have recovered their health taking 1 or 2 drops per hour, and in rare cases even less. It is best to start out slow and ...
http://mmswiki.is/index.php?title=Protocol_1000&oldid=2527
Kubke Lab:Protocols - OpenWetWareKubke Lab:Protocols - OpenWetWare
List of Protocol pages. To create a protocol page please use the following naming convention: Kubke_Lab:Protocols/Protocol_name ...
https://openwetware.org/wiki/Kubke_Protocols
The Dulce Protocol by Robert Teske - Free PDF - Page 15The Dulce Protocol by Robert Teske - Free PDF - Page 15
Jul 3, 2014 ... Rather, our focus is on the ability of more exclusive approaches to ... 2 This is how the CBD defines genetic resources, Article 2, Use of .... 5 The exact temporal and functional scopes of the Nagoya Protocol are ... development and im... ...
http://www.incense-wholesale.com/related/the-dulce-protocol/page-14/
S-(2-thiopyridyl)mercaptopropionohydrazide | Semantic ScholarS-(2-thiopyridyl)mercaptopropionohydrazide | Semantic Scholar
Liposome antibody conjugates are potentially useful as a means of targeting drugs to specific tissues. A new protocol for the… Expand ...
https://www.semanticscholar.org/topic/S-%282-thiopyridyl%29mercaptopropionohydrazide/3294310
STroke imAging pRevention and treatment (START): a longitudinal stroke cohort study: clinical trials protocolSTroke imAging pRevention and treatment (START): a longitudinal stroke cohort study: clinical trials protocol
Rationale: Stroke and poststroke depression are common and have a profound and ongoing impact on an individuals quality of life. However, reliable biological correlates of poststroke depression and functional outcome have not been well established in humans. Aims: Our aim is to identify biological factors, molecular and imaging, associated with poststroke depression and recovery that may be used to guide more targeted interventions. Design: In a longitudinal cohort study of 200 stroke survivors, the START - STroke imAging pRevention and Treatment cohort, we will examine the relationship between gene expression, regulator proteins, depression, and functional outcome. Stroke survivors will be investigated at baseline, 24h, three-days, three-months, and 12 months poststroke for blood-based biological associates and at days 3-7, three-months, and 12 months for depression and functional outcomes. A sub-group (n=100), the PrePARE: Prediction and Prevention to Achieve optimal Recovery Endpoints after ...
https://ogma.newcastle.edu.au/vital/access/%20/manager/Repository/uon:23444?view=null&f0=sm_creator%3A%22O%27+Collins%2C+Victoria%22&sort=null
2010 - Modules, Aberystwyth University2010 - Modules, Aberystwyth University
On successful completion of this module students should be able to: Demonstrate a detailed knowledge of the epidemiological and pathophysiological evidence which underpins current guidelines for the inclusion of physical activity in the maintenance of a healthy lifestyle; Demonstrate an awareness of pre-assessment screening, risk stratification and issues related to the selection of safe and appropriate physiological assessment protocols for both healthy individuals and those suffering from chronic disease; Interpret and evaluate data from physiological assessment protocols and demonstrate an awareness of validity and reliability issues ...
https://www.aber.ac.uk/en/modules/2010/SS32320/
Everything About Wood: Sampling termite assemblages in tropical forests: testing a rapid biodiversity assessment protocolEverything About Wood: Sampling termite assemblages in tropical forests: testing a rapid biodiversity assessment protocol
Given the continued destruction, disturbance and fragmentation of tropical forests, and the associated extinction of species (Sayer & Whitmore 1991; May, Lawton & Stork 1995; Turner 1996), there is an urgent need to develop and test standardized methods for sampling biodiversity (Sutton & Collins 1991; Stork & Samways 1995). This has prompted a growing literature on the search for bioindicators, particularly for insects, because they form the bulk of species and animal biomass in terrestrial habitats and have a strong influence over many ecosystem processes. McGeoch (1998) reviewed the selection and utility of insects as indicators, and emphasized the need for explicit aims and hypothesis testing when nominating a species or group of taxa as a bioindicator. The basic purpose of bioindicators, whatever the ultimate aim, is to indicate a relationship with another biotic or abiotic variable. These relationships with other variables are, however, only as good as the sampling method employed to ...
http://woodethic.blogspot.com/2016/09/sampling-termite-assemblages-in.html
Protocol development for assays of bone and cartilage tissues from mouse tibio-femoral joints - Melbourne School of EngineeringProtocol development for assays of bone and cartilage tissues from mouse tibio-femoral joints - Melbourne School of Engineering
The Integrative Cartilage Research Group at the University of Melbourne researches links between microstructure, mechanics and biological signalling networks.. Glycosaminoglycans, collagen, DNA, and mineral content are just some of the markers used to understand biological tissue quality. Reproducibly extracting and measuring these markers from small structures (e.g. mouse knees) can be challenging. In this work, we are developing robust in vivo protocols that will form the foundation for future research projects.. The ICR Group is developing, refining, and using biomedical engineering tools and concepts, to explore and understand the effects of mechanics on living musculoskeletal systems on the molecular, cellular, and organ level of organisation, while maintaining a philosophy of respect and compassion for all human and animal life.. The project involves monitoring of biosignals and biomarkers in biological constructs and in vivo animal models. The work requires a creative approach to ...
http://www.eng.unimelb.edu.au/research/projects/protocol-development-for-assays-of-bone-and-cartilage-tissues-from-mouse-tibio-femoral-joints-387
Searching for management approaches to reduce HAI transmission (SMART): a study protocol | Implementation Science | Full TextSearching for management approaches to reduce HAI transmission (SMART): a study protocol | Implementation Science | Full Text
Explicate the Management Strategies and Strategic Components to Identify Structural Practices (Participants: approximately 5775 online participants).. We propose to use an iterative online engagement strategy based on the Qualtrics [40] platform to explore variation in Management Strategies and Structural Practices focused on HAI-prevention across an initial sample of hospitals. In this step, we will build a survey instrument and deploy a computer-assisted Delphi method to conduct this assessment. The Delphi method is an iterative engagement technique where knowledgeable individuals are systematically asked a series of questions in multiple rounds of queries in five process stages, Preparation, Generation, Structure, Analysis, and Summary. Throughout this process, the research team will provide summaries of results to participants as findings emerge across the different participants perspectives. The Delphi study stages are explained below.. Stage 1, Preparation will involve identification of ...
https://implementationscience.biomedcentral.com/articles/10.1186/s13012-017-0610-z
Protocol-Driven Primary Care and Community Linkages to Improve Population Health in Rural Zambia: the Better Health Outcomes...Protocol-Driven Primary Care and Community Linkages to Improve Population Health in Rural Zambia: the Better Health Outcomes...
|strong|Introduction|/strong|: Zambias under-resourced public health system will not be able to deliver on its health-related Millennium Development Goals without a substantial acceleration in mortality reduction. Reducing mortality will depend not only upon increasing access to health care but also upon improving the quality of care that is delivered. Our project proposes to improve the quality of clinical care and to improve utilization of that care,through a targeted quality improvement (QI) intervention delivered at the facility and community level. |strong|Description of implementation|/strong|: The project is being carried out 42 primary health care facilities that serve a largely rural population of more than 450,000 in Zambias Lusaka Province. We have deployed six QI teams toimplement consensus clinical protocols, forms, and systems at each site. The QI teams define new clinical quality expectations and provide tools needed to deliver on those expectations. They also monitor the care that
https://www.issuelab.org/resource/protocol-driven-primary-care-and-community-linkages-to-improve-population-health-in-rural-zambia-the-better-health-outcomes-through-mentoring-and-assessment-bhoma-project.html
Simplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia - Full Text View - ClinicalTrials.govSimplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia - Full Text View - ClinicalTrials.gov
In recent years, evidence-based protocols of bundled therapies have improved survival of severe sepsis in developed countries. In sub-Saharan Africa, simple therapies such as IV fluids and early antibiotics are frequently under-utilized. Studies of fluid interventions in the region, however, have demonstrated conflicting results. Outcomes in septic patients may be further affected by delays in the diagnosis of tuberculosis-associated severe sepsis.. The aims of this study are (1) To assess the impact on survival of a simple evidence-based protocol for severe sepsis with hypotensionor septic shock, (2) To evaluate the cost of implementation for a simplified severe sepsis protocol, (3) To develop a clinical diagnostic score for identifying tuberculosis in HIV positive patients with severe sepsis, and (4) To assess the performance of the Xpert TB/RIF rapid PCR system and urine lipoarabinomannan assay for diagnosing tuberculosis in HIV positive patients with severe sepsis. ...
https://clinicaltrials.gov/ct2/show/NCT01663701?term=blood+transfusion&recr=Open&fund=01&rank=18
Simplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia - Full Text View - ClinicalTrials.govSimplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia - Full Text View - ClinicalTrials.gov
In recent years, evidence-based protocols of bundled therapies have improved survival of severe sepsis in developed countries. In sub-Saharan Africa, simple therapies such as IV fluids and early antibiotics are frequently under-utilized. Studies of fluid interventions in the region, however, have demonstrated conflicting results. Outcomes in septic patients may be further affected by delays in the diagnosis of tuberculosis-associated severe sepsis.. The aims of this study are (1) To assess the impact on survival of a simple evidence-based protocol for severe sepsis with hypotensionor septic shock, (2) To evaluate the cost of implementation for a simplified severe sepsis protocol, (3) To develop a clinical diagnostic score for identifying tuberculosis in HIV positive patients with severe sepsis, and (4) To assess the performance of the Xpert TB/RIF rapid PCR system and urine lipoarabinomannan assay for diagnosing tuberculosis in HIV positive patients with severe sepsis. ...
https://clinicaltrials.gov/ct2/show/NCT01663701?term=Hypotension&recr=Open&fund=01&rank=8
Better Access to Information about Clinical Trials | Annals of Internal Medicine | American College of PhysiciansBetter Access to Information about Clinical Trials | Annals of Internal Medicine | American College of Physicians
Because the advantages of clinical trials registries are so great and because several forces now demand their creation, the challenge is to develop systems that will be accessible to a range of persons and serve a range of interrelated purposes (39). Given these broad goals, several authors have suggested the types of elements that should be included in a clinical trials registry (7, 22, 25, 27). All agree on the high-level categories of information that should be present in a full clinical trials protocol (40), although there are differences in the emphasis placed on those categories. General and administrative information includes the trial name or title, a registration number, the funding source, the site at which the trial is being conducted, the name and affiliation of the investigators, the study start and completion dates, and the recruiting status of the trial. The purpose and objectives of the trial include the disease or condition being treated or evaluated, the treatments or ...
http://annals.org/aim/fullarticle/713934/better-access-information-about-clinical-trials
Management of the infertile couple: an evidence-based protocol | Reproductive Biology and Endocrinology | Full TextManagement of the infertile couple: an evidence-based protocol | Reproductive Biology and Endocrinology | Full Text
Infertility is defined as inability of a couple to conceive naturally after one year of regular unprotected sexual intercourse. It remains a major clinical and social problem, affecting perhaps one couple in six. Evaluation usually starts after 12 months; however it may be indicated earlier. The most common causes of infertility are: male factor such as sperm abnormalities, female factor such as ovulation dysfunction and tubal pathology, combined male and female factors and unexplained infertility. The aim of this study is to provide the healthcare professionals an evidence-based management protocol for infertile couples away from medical information overload. A comprehensive review where the literature was searched for
https://rbej.biomedcentral.com/articles/10.1186/1477-7827-8-21
ESTABLISHMENT OF CLINICAL PROTOCOL TARGETING CANCER STEM CELLS IN RECURRENT GLIOBLASTOMA USING HIGH-THROUGHPUT DRUG SCREENINGESTABLISHMENT OF CLINICAL PROTOCOL TARGETING CANCER STEM CELLS IN RECURRENT GLIOBLASTOMA USING HIGH-THROUGHPUT DRUG SCREENING
Skaga, Erlend; Kulesskiy, Evgeny; Brynjulfsen, Marit; Sandberg, Cecilie Jonsgar; Kyttala, Aija; Langmoen, Iver Arne; Laakso, Aki; Gaal-Paavola, Em-Lia; Perola, Markus; Wennerberg, Krister; Vik-Mo, Einar ...
http://julkari.fi/handle/10024/135662
Most recent papers with the keyword geriatric anaesthesia | Read by QxMDMost recent papers with the keyword geriatric anaesthesia | Read by QxMD
BACKGROUND AND AIMS: Several changes in the management protocols of anaesthesia for geriatric patients were introduced into clinical practice to improve the outcome. Very few studies have evaluated the impact of these management protocols. The aim of our study was to evaluate impact of some of the changes in the peri-operative management protocols of geriatric patients undergoing elective orthopaedic lower limb surgeries on the outcomes. METHODS: A retrospective chart review of thirty-eight surgical patients from 1999 (Group 1999) before the introduction of changes and 107 patients from 2007 (Group 2007) after establishing changes was performed and data of peri-operative variables were collected and analysed ...
https://www.readbyqxmd.com/keyword/107765
PLOS Medicine: Inadequate Dissemination of Phase I Trials: A Retrospective Cohort StudyPLOS Medicine: Inadequate Dissemination of Phase I Trials: A Retrospective Cohort Study
François Chapuis and colleagues examine a cohort of clinical trial protocols approved by French ethics committees, and show that Phase I trials are less frequently published than other types of trials.
https://journals.plos.org/plosmedicine/article/authors?id=10.1371/journal.pmed.1000034
PLOS Medicine: Inadequate Dissemination of Phase I Trials: A Retrospective Cohort StudyPLOS Medicine: Inadequate Dissemination of Phase I Trials: A Retrospective Cohort Study
François Chapuis and colleagues examine a cohort of clinical trial protocols approved by French ethics committees, and show that Phase I trials are less frequently published than other types of trials.
https://journals.plos.org/plosmedicine/article/comments?id=10.1371/journal.pmed.1000034
Acute effects of reducing sitting time in adolescents: a randomized cross-over studyAcute effects of reducing sitting time in adolescents: a randomized cross-over study
The trial was registered as a clinical trial with the Australian and New Zealand Clinical Trials Registry ( ACTRN12614001064695 ) on the 3rd of October 2014 - registered retrospectively.
https://pubmed.ncbi.nlm.nih.gov/28810853/?dopt=Abstract
Prednisone 3 times a day - Prix viagra pharmacie algerie 2017Prednisone 3 times a day - Prix viagra pharmacie algerie 2017
Prednisone didnt make. This is why I wait at least three months. kept them satiated without feeling hungry all day.Most of them did fine on.Clinical trial protocol. Treatment repeats every 3 weeks until day 365 from the beginning of. *Patients receive oral prednisolone 3 times daily on.. prednisone 20 mg tablets for dogs, prednisone 10 mg package insert, prednisone 20 mg 3 times daily, buy prednisone dose pack, prednisone 20 mg dosing.area 2-3 times a day. eur-lex.europa.eu. ES A method for preparing a transdermal absorptive drug formulation containing 3-isobutyryl-2-isopropylpyrazolo.. Avoid contact with people friday glucocorticoid effects of prednisone 3 minutes for. not potentiate the beta times times the anti. teens consume each day.3) Accords barrés (avancé) 4) Les power chords; Accords à 4 sons. 1) Les accords 7ème de dominante; 2) Les accords Majeurs 7 ouverts; 3) Transposition des accords.To help acne how to take 10mg 6 5 4 3 2 1 50lb dog 50mg prednisone thrombocytopenia heart ...
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NOT REAL NEWS: A look at what didnt happen this week | Hawaii Tribune-HeraldNOT REAL NEWS: A look at what didnt happen this week | Hawaii Tribune-Herald
Here are the facts:. ___. COVID-19 vaccine does not spread by inhalation or skin contact. CLAIM: Pfizer admits in its COVID-19 clinical trial protocol document that vaccinated people can shed the vaccine, emitting materials that can spread to unvaccinated people by inhalation or skin contact.. THE FACTS: Pfizers COVID-19 vaccine does not shed from person to person, nor has the company admitted any such thing. The Pfizer-BioNTech COVID-19 vaccine is a synthetic mRNA vaccine and does not contain any virus particles. Because there is no virus produced in the body, no shedding occurs within the human body, Pfizer spokesperson Jerica Pitts told The Associated Press in an email. The vaccine cannot be inhaled via shedding and can only enter the human body through an administered dose. The U.S. Food and Drug Administration approved Pfizers vaccine in December after extensive clinical trials. Women who were pregnant or breastfeeding were excluded from joining those early clinical studies, and ...
https://www.hawaiitribune-herald.com/2021/05/08/features/not-real-news-a-look-at-what-didnt-happen-this-week-25/
Nivestim 12 MU/ 0.2 ml solution for injection/infusion, Nivestim 30 MU/ 0.5 ml solution for injection/infusion, Nivestim 48MU/...Nivestim 12 MU/ 0.2 ml solution for injection/infusion, Nivestim 30 MU/ 0.5 ml solution for injection/infusion, Nivestim 48MU/...
Nivestim 12 MU/ 0.2 ml solution for injection/infusion, Nivestim 30 MU/ 0.5 ml solution for injection/infusion, Nivestim 48MU/ 0.5 ml solution for injection/infusion - Summary of Product Characteristics (SmPC) by Hospira UK Ltd
https://www.medicines.org.uk/emc/product/575
Early-goal directed therapy for septic shock: is it the end? - Minerva Anestesiologica 2015 October;81(10):1138-43 - Minerva...Early-goal directed therapy for septic shock: is it the end? - Minerva Anestesiologica 2015 October;81(10):1138-43 - Minerva...
Three randomized clinical trials have recently provided data on the lack of effectiveness of early-goal directed therapy (EGDT) (i.e. optimization of tissue oxygenation in the first 6 hours since sepsis diagnosis using different therapeutic interventions based on the assessment of the central venous oxygen saturation to titrate such interventions) in the initial management of patients with septic shock. In a first trial including 31 US hospitals (the ProCESS study, N.=1341), three different therapeutic strategies (EGDT vs. protocol-based therapy vs. usual care) were compared and no difference in the primary endpoint (60-day mortality) was found (EGDT 21%, protocol-based therapy 18% and usual care 19%). No significant difference in death by 90 days or in other secondary outcomes, including serious adverse events, was found, as well. A second trial (ARISE, N.=1600), mostly conducted in Australia and New Zealand, randomized patients to EGDT or usual care. Ninety-day mortality was similar between ...
https://www.minervamedica.it/it/riviste/minerva-anestesiologica/articolo.php?cod=R02Y2015N10A1138
Diversity and Democracy | Volume 12, Number 1 | Designing a Model for International Learning AssessmentDiversity and Democracy | Volume 12, Number 1 | Designing a Model for International Learning Assessment
Assessment should begin with a review of the institutions mission statement and overall goals. What are the institutions priorities, and what evidence can demonstrate their achievement? How can the institution best combine summative assessment (which focuses on learners development at a particular time) and formative assessment (a more holistic approach that uses multiple points of measurement to provide continuous feedback and improve educational opportunities) to meet its goals? By answering these and related questions, administrators can determine which assessment methods and tools to use.. The next step in developing an assessment protocol is to explore the institutional context and available resources, including others who are already engaged in assessment. This process should lead to the creation of a multiunit assessment team, as the undertaking is too complex for any one office to implement. The team should develop an assessment plan and review it regularly for refinement. Table 1 ...
http://diversityweb.org/DiversityDemocracy/vol12no1/sternberger.cfm
Get lean. Lose the stomach fat. Keep it off. - AYO Training NutritionGet lean. Lose the stomach fat. Keep it off. - AYO Training Nutrition
In order to achieve this, all clients must go through an initial consultation process so that together we can ascertain the level of intervention required for your success. The process includes a visual food diary analysis, remote Movement Assessment Protocol, and current situation assessment. Our conversations coupled with the data these tests provide enables the delivery of a suite of interventions which empower you to make positive changes and maintain that success. Crucially, you will be supported throughout the process, with access to personal, world class expertise monitoring your training, guiding your nutritional decisions and keeping you on track.. Achieve Your Objective is based on two decades worth of experience of working both in-person and remotely to help create solutions to the challenges that modern life presents to self-care. If you are pressed for time, and would like to take positive, supported steps to looking and feeling better, get in touch now or apply here ...
https://www.ayotrainingnutrition.com/
DRKS - Deutsches Register Klinischer Studien (German Clinical Trials Register)DRKS - Deutsches Register Klinischer Studien (German Clinical Trials Register)
Subarachnoid hemorrhage, traumatic brain injury and cardiogenic shock are diseases that can be life-threatening and might require weeks of intensive medical care. Administration of medication is an essential part of the treatment. According to current practice, the route of drug administration in critically ill patients can be enteral or parenteral depending on the available drug format and vigilance of patients. However, there are many studies in the literature that report a disturbance of gastrointestinal function in critically ill patients. Therefore, the question of whether the enteral route of drug administration in critically ill patients is pharmacokinetically meaningful should be investigated in this study ...
https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00017624
DRKS - Deutsches Register Klinischer Studien (German Clinical Trials Register)DRKS - Deutsches Register Klinischer Studien (German Clinical Trials Register)
The aim of this non-investigational study is to determine the symptoms and burden at the moment of diagnosis and in the further course of an incurable cancer disease. The needs and preferences of patients suffering from cancer (ovarian carcinoma, breast cancer, malignant melanoma, lung cancer, stomach cancer, oesophageal cancer, pancreatic cancer, cancer of the hepatobiliary system, colorectal cancer, head and neck cancer) will be examined by various questionnaires. The data obtained by these questionnaires will be collected together with information obtained by the treating physicians at four time points during the study: T0 - patient´s enrollment, at the moment of diagnosis and before the start of tumor therapy, respectively; T1 - 3 months after the patient´s enrollment; T2 - 6 months after the patient´s enrollment; T3 - 12 months after the patient´s enrollment. This highly innovative project offers the chance to identify medical services deficits and risk circumstances for the burden of ...
https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00007536
Grants:Project/Browse applications - MetaGrants:Project/Browse applications - Meta
IMPORTANT NOTICE: We have updated our guidelines regarding organizing in-person events with Wikimedia Foundation grant funding. Our new COVID-19 Risk Assessment protocol for in-person gatherings is designed to be sensitive to the constantly changing circumstances around this pandemic, and allow potential grantees and community members to assess their own ability to safely host events and activities. If you are planning an in-person event plan to request funding, please follow the steps described in these guidelines before submitting a grant proposal. For current grants already in progress, please contact your program officer if you would like to include or change your activities to include in-person activities ...
https://meta.m.wikimedia.org/wiki/Grants:Project/Browse_applications
Master of Science in Translational ResearchMaster of Science in Translational Research
Students are required to engage in a research project of their own design under the supervision of the primary mentor. At the time of application, each student specifies the project they will pursue, along with the primary mentor who will supervise the research project. Students will use class material and homework assignments to assist in protocol development.. The research should be translational in nature and involve direct measurements on patient-derived samples or the use of innovative therapeutic or diagnostic techniques with laboratory-based elements. There should be demonstrable clinical relevance. The protocol is to be designed by the student under the direct supervision of the mentor. Where appropriate, dual mentorship should be considered; including a basic scientist expert in the technology being used and a clinical investigator expert in the condition being studied. The primary protocol should account for at least 75-80% of the students commitment to the program.. Trainees are ...
https://www.itmat.upenn.edu/itmat/education-and-training/master-of-science-in-translational-research/
Cancer Therapy Evaluation Program (CTEP)Cancer Therapy Evaluation Program (CTEP)
Provides support of protocol development and conduct through the Protocol and Information Office, PIO, as the operations hub, processes all submissions and liaisons with all clinical sites. OIB also developed and maintains the CTEP Enterprise System, in use by the NCI as well as the extramural community, to collect, analyze and report a wide variety of protocol, accrual, adverse event and agent information ...
https://cybercemetery.unt.edu/archive/oilspill/20130213205433/http:/ctep.cancer.gov/default.htm
Potential Effect of Interfacial Bonding on Used Nuclear Fuel Vibration Reliability (Conference) | SciTech ConnectPotential Effect of Interfacial Bonding on Used Nuclear Fuel Vibration Reliability (Conference) | SciTech Connect
This summary abstract describes the methodology used to evaluate the effect of pellet pellet and pellet clad interactions with consideration of the interfacial bonding efficiency on UNF vibration integrity. This methodology provides a solid roadmap for further protocol development with respect to effective lifetime prediction of a UNF system under normal transportation vibration. The proposed methodology that couples FEA simulations and experimental exploration efforts is also under development. The current methodology is focused on assessing the influence of interfacial bonding at the pellet pellet and the pellet clad interfaces on UNF vibration integrity. The FEA simulation results were also calibrated and benchmarked with the fatigue aging data obtained from reversible bending fatigue testing. ...
https://www.osti.gov/scitech/biblio/1157099-potential-effect-interfacial-bonding-used-nuclear-fuel-vibration-reliability
Home Page | azmedmj.orgHome Page | azmedmj.org
The intent of these learning modules is to provide consistent and concise information to all providers. The content of the Module has been reviewed by the Protocol Development and Review Sub-Committee, and, where applicable, includes the specific standing order, resource and reference material, and instructions for completing the Self-Learning Module to obtain continuing education credit. One hour of SAEMS continuing education credit may be issued following successful completion of the module.. EMS Self-Learning Modules. ...
http://www.azmedmj.org/home
Animal ModelsAnimal Models
Imperials world-class animal facility offers a wide range of in vitro and in vivo pre-clinical vaccine development and anti-infective testing capabilities. The highly experienced team can also provide protocol development, data analysis and write up for publications.. The team, led by Dr John Tregoning, use well established animal models to provide effective read outs of vaccine or anti-infectives efficacy.. Animal challenges are carried out using human disease strains, instead of mouse-adapted strains, that may not be as translatable - plus well-validated immunogenicity assays are used to assess immune responses, which are interpreted by scientists with many years experience in immunology.. ...
https://www.imperial-consultants.co.uk/areasofexpertise/animal-models/
Clinical Trial Phases | FDA | Eye Research | Cincinnati | Apex EyeClinical Trial Phases | FDA | Eye Research | Cincinnati | Apex Eye
Clinical Research, Clinical Study, Clinical Trial, and Clinical Protocol all concern the same topic. These terms are often used interchangeably to talk about scientific studies that use people to understand if new drugs, treatments and devices are safe and effective. Clinical studies cannot happen until basic research in a laboratory determines the new treatment, drug or device is successful and safe. Once basic research indicates scientific promise, the FDA must approve continuing the research and beginning to test in people. Carefully controlled and well-designed clinical trials are performed by highly trained medical professionals to understand how this new treatment will work in people. The clinical trial is trying to duplicate the promising lab results in people.. Clinical Trials are conducted in four phases that occur in sequential order. Each phase tends to have a different purpose and helps answer different questions. Each phase is considered a separate trial. After completion of each ...
http://apexeye.com/clinical-research/patient-participants/clinical-trial-phases-fda/
NIH Honors Moayeri 20 for Exceptional Biomedical Research | Harvey Mudd College NewsNIH Honors Moayeri 20 for Exceptional Biomedical Research | Harvey Mudd College News
As a resident computer scientist at NINDS Translational Neuroradiology Section (TNS) lab, Moayeri developed code that helped accelerate data-processing steps in experiments tied to spinal cord research and worked side by side with leading scientists conducting basic and clinical biomedical research. He also worked in the clinical center, which left him with a strong sense of validation that his contributions could make a difference.. Often, patients who come to the NIH come out of necessity, as the already established clinical protocols are not sufficient to help these patients, says Moayeri. Seeing how many people would come from all over the country to the NIH really led me to believe in what I was working on and gave me a new sense of purpose.. Moayeris work in the TNS lab focused on measuring and capturing data of MS disease evolution taken from magnetic resonance imaging (MRI). Examining MRI scans of spinal cord lesions, Moayeri isolated quantitative data. Typically, this ...
https://www.hmc.edu/about-hmc/2017/11/15/nih-honors-moayeri-20-exceptional-biomedical-research/
FDA Announces New Protocol for the Development and Registration of Treatments for Preharvest Agricultural WaterFDA Announces New Protocol for the Development and Registration of Treatments for Preharvest Agricultural Water
/PRNewswire/ -- Today, the U.S. Food and Drug Administration announced a new protocol for the development and registration of antimicrobial treatments for...
https://www.prnewswire.com/news-releases/fda-announces-new-protocol-for-the-development-and-registration-of-treatments-for-preharvest-agricultural-water-301103446.html
New protocol to visualize gene expression in intact and regenerating adult planarians by whole mount in situ hibridization<...New protocol to visualize gene expression in intact and regenerating adult planarians by whole mount in situ hibridization<...
TY - JOUR. T1 - New protocol to visualize gene expression in intact and regenerating adult planarians by whole mount in situ hibridization. AU - Bueno, D. AU - Castillo, E. AU - Vispo, M. AU - Cebrià, F. AU - Bayascas, JR. AU - Saló, E. AU - Romero, R. PY - 1997/1/1. Y1 - 1997/1/1. M3 - Article. SP - 1. EP - 1. ER - ...
https://portalrecerca.uab.cat/en/publications/new-protocol-to-visualize-gene-expression-in-intact-and-regenerat
Enhanced Recovery After Spine Surgery: A Systematic Review. | AAPMEnhanced Recovery After Spine Surgery: A Systematic Review. | AAPM
Enhanced recovery after surgery (ERAS) is a multidimensional approach to improving the care of surgical patients using subspecialty- and procedure-specific evidence-based protocols. The literature provides evidence of the benefits of ERAS implementat
https://painmed.org/pain-research/enhanced-recovery-after-spine-surgery-a-systematic-review
Osteosarcoma Clinical Trials : Eleison Pharmaceuticals LLCOsteosarcoma Clinical Trials : Eleison Pharmaceuticals LLC
ILC Phase II Clinical Trial for Osteosarcoma. Eleison is also developing drug candidate ILC, a lipid-complexed cisplatin administered via inhalation. ILC is currently being evaluated under a Phase II clinical protocol for certain patients with osteosarcoma (bone cancer).
http://eleison-pharma.com/osteosarcoma-clinical-trials.php
Meet the employers - University of CopenhagenMeet the employers - University of Copenhagen
The global development unfolds in collaboration between academia, pharmaceutical companies, health care professionals as well as patients. It includes the quality of medicines, global clinical protocols, and studies. This contributes to an increased understanding of global health aspects to the benefit of patients health (efficacy and safety) and the global societies health development. The regulatory staff works on a daily basis with these complex issues in order to guarantee that the development and continued market access of the medicines comply with international standards for quality, efficacy and safety. This has resulted in a growing demand for employees with high regulatory competences especially in eg. the pharmaceutical industry, health authorities and academia.. ...
https://mra.ku.dk/employers/
ICIM: Your Between Conference ConnectionICIM: Your Between Conference Connection
Founded in 1994, Theralase Technologies Inc. designs, develops and manufactures super-pulsed, cool laser technology for a wide range of human, companion animal and equine applications. Theralase is committed to provide cutting-edge pre-clinical and clinical research to remain the most clinically and scientifically supported therapeutic medical laser on the market. The highly trained scientific, clinical and engineering Theralase team continuously brings our valued customers the most advanced technology on the market, while our sales, marketing, clinical training, customer service and finance teams bring superior customer service, the latest interactive training, the most up to date clinical protocols and the best financing options to accelerate the financial and clinical success of your practice. READ MORE ...
http://multibriefs.com/briefs/ICIM/ICIM083016.php
SLE: reconciling heterogeneity | Lupus Science & MedicineSLE: reconciling heterogeneity | Lupus Science & Medicine
One can reduce the complexity of making a diagnosis of SLE by using conceptual models. There are two such models, one separate illnesses, the other linear illness; both cluster SLEs disparate elements. The separate illnesses model posits that typical, overlap, UAS and antibody-only SLE are separate but related illnesses. A strength of this model is that it assigns different, targetable biological mechanisms to each diagnosis. Another strength is that a diagnosis, once made, does not change.37-40 Weaknesses of this model are that, in clinical practice, ambiguous diagnoses occur often, blurring the separating lines, and that diagnoses do sometimes change. Clinical protocols that rigidly adhere to sharp distinctions among diagnoses may remove options available to the treating physician. Another weakness is that insights suggested by evolving phenotypes may be unseen if an investigator believes that change of diagnosis cannot occur.30 The linear illness model posits that UAS, overlap, antibody-only ...
https://lupus.bmj.com/content/6/1/e000280
What We Do - Cabernet Pharmaceuticals Inc.What We Do - Cabernet Pharmaceuticals Inc.
Cabernet works closely with clients to understand their needs and goals and then deliver timely, executable clinical protocols that provide actionable answers for the key scientific, regulatory, and payer questions in all phases of drug development. We also develop study documentation, such as study-procedure manuals, informed consents, and clinicaltrials.gov summaries. We can create and manage external clinical-study committees including advisory, adjudication, and drug-safety monitoring boards.. ...
https://cabernetpharma.com/what-we-do/
Motion correction in medical imaging. - Surrey Research Insight Open AccessMotion correction in medical imaging. - Surrey Research Insight Open Access
It is estimated that over half of current adults within Great Britain under the age of 65 will be diagnosed with cancer at some point in their lifetime. Medical Imaging forms an essential part of cancer clinical protocols and is able to furnish morphological, metabolic and functional information. The imaging of molecular interactions of biological processes in vivo with Positron Emission Tomography (PET) is informative not only for disease detection but also therapeutic response. The qualitative and quantitative accuracy of imaging is thus vital in the extraction of meaningful and reproducible information from the images, allowing increased sensitivity and specificity in the diagnosis and precision of image guided treatment. Furthermore the utilization of complementary information obtained via Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) in integrated PET-CT and PET-MR devices offers the potential for the synergistic effects of hybrid imaging to provide increased detection and ...
http://epubs.surrey.ac.uk/841883/
Methylation - Vanita DahiaMethylation - Vanita Dahia
Testing of methylation goes beyond MTHFR.. Learn about the methylation process, genetic testing for potential defects and clinical protocols for testing the methylation function and effective treatment options which include dietary changes and the proper supplementation.. This webinar will give you clinical and practical guidance in:. ...
https://vanitadahia.com/learning-centre/webinars/methylation/
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. - ORA - Oxford...Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. - ORA - Oxford...
In mouse, a subset of dendritic cells (DCs) known as CD8alpha+ DCs has emerged as an important player in the regulation of T cell responses and a promising target in vaccination strategies. However, translation into clinical protocols has been hampered by the failure to identify CD8alpha+ DCs in
https://ora.ox.ac.uk/objects/uuid:a53ef689-d20a-4797-bdd0-673de5a538f1
IQ ScriptsIQ Scripts
Use IQ Scripts to gain control over your clinical processes. IQ Scripts define patient pathways and clinical protocols, and how MOSAIQ collects data.
https://www.elekta.com/software-solutions/care-management/iq-scripts/
NATO Adopts New Protocol Standard for Underwater Communications - NewsNATO Adopts New Protocol Standard for Underwater Communications - News
Underwater transmission protocols may finally be unified in a protocol that aims to help interconnectivity with devices ranging from buoys to submarines.
https://www.allaboutcircuits.com/news/janus-nato-new-protocol-standard-underwater-communications/
Kate TchanturiaKate Tchanturia
"Clinical packages & Protocols". katetchanturia.com. "PEACE Pathway Website". peacepathway.org. Tchanturia, Kate, (2015). Brief ... Pathway for Eating disorders and Autism developed from Clinical Experience). This clinical pathway was funded by The Health ... After relocating to London in 1997, she became a clinical research fellow at the Institute of Psychiatry, King's College London ... She has developed a novel clinical pathway for patients with comorbid autism spectrum disorders and eating disorders at the ...
https://en.wikipedia.org/wiki/Kate_Tchanturia
Canavan diseaseCanavan disease
"Clinical protocol. Gene Therapy of Canavan Disease: AAV-2 Vector for Neurosurgical Delivery of Aspartoacylase Gene (ASPA) to ...
https://en.wikipedia.org/wiki/Canavan_disease
Healthcare in BelizeHealthcare in Belize
Limited clinical protocols for patient management. Limited technical operational manuals for program implementation. Health ...
https://en.wikipedia.org/wiki/Healthcare_in_Belize
BreastfeedingBreastfeeding
"ABM Clinical Protocol #11. 1 (1): 3. doi:10.1186/1746-4358-1-3. PMC 1464379. PMID 16722609.. ... Hanson LA, Söderström T (1981). "Human milk: Defense against infection". Progress in Clinical and Biological Research. 61: 147- ... Hendrickson RG, McKeown NJ (January 2012). "Is maternal opioid use hazardous to breast-fed infants?". Clinical Toxicology. 50 ( ... Haastrup MB, Pottegård A, Damkier P (February 2014). "Alcohol and breastfeeding". Basic & Clinical Pharmacology & Toxicology. ...
https://en.wikipedia.org/wiki/Breast-feeding
Intersex medical interventionsIntersex medical interventions
In 2006, an invited group of clinicians met in Chicago and reviewed clinical evidence and protocols, and adopted a new term for ... Alice Dreger, a US professor of Clinical Medical Humanities and Bioethics, argues that little has changed in actual clinical ... Large majorities of respondents opposed standard clinical protocols.[71] 2016 Global DSD Update[edit]. A 2016 follow-up to the ... The committee stated: "clinical intervention pathways stated to be based on probabilities of cancer risk may be encapsulating ...
https://en.wikipedia.org/wiki/Intersex_medical_interventions
Virginity testVirginity test
Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... Clinical and Pathological Aspects, Greenwich Medical Media: London, a)p.453, b)p.455 c)p.460. "Muslim women in France regain ...
https://en.wikipedia.org/wiki/Virginity_test
VirginityVirginity
Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... Clinical and Pathological Aspects, Greenwich Medical Media: London, a)p.453, b)p.455 c)p.460. The Marks of Childhood or the ... vaginal examinations for verifying a woman's virginity are a clinical practice which are at times state-enforced. These types ...
https://en.wikipedia.org/wiki/Virginity
List of common misconceptionsList of common misconceptions
Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... US Navy protocols discourage the practice, while the other four branches have specific regulations against it. Legal tender ... Kopelman M. D.; Thomson A.D.; Guerrini I.; Marshall E.J. (2009). "The Korsakoff syndrome: clinical aspects, psychology and ... Weisberger, L; Jamieson, B (July 2009). "Clinical inquiries: How can you help prevent a recurrence of diverticulitis?". The ...
https://en.wikipedia.org/wiki/List_of_common_misconceptions
VaginaVagina
ISBN 978-0-7131-4452-9. Perlman SE, Nakajyma ST, Hertweck SP (2004). Clinical protocols in pediatric and adolescent gynecology ... ISBN 978-0-323-29358-7. Alldredge BK, Corelli RL, Ernst ME (2012). Koda-Kimble and Young's Applied Therapeutics: The Clinical ... ISBN 978-0-495-11308-9. Sirven JI, Malamut BL (2008). Clinical Neurology of the Older Adult. Lippincott Williams & Wilkins. pp ... ISBN 978-1-135-82509-6. Balon R, Segraves RT (2009). Clinical Manual of Sexual Disorders. American Psychiatric Pub. p. 258. ...
https://en.wikipedia.org/wiki/Vagina
HymenHymen
Perlman, Sally E.; Nakajyma, Steven T.; Hertweck, S. Paige (2004). Clinical protocols in pediatric and adolescent gynecology. ... Clinical and Pathological Aspects, Greenwich Medical Media: London, a)p.453, b)p.455 c)p.460. Heger, Astrid; Emans, S. Jean; ... Journal of Clinical Forensic Medicine. 13 (4): 172-180. doi:10.1016/j.jcfm.2006.02.006. ISSN 1353-1131. PMID 16564196. Hymen ...
https://en.wikipedia.org/wiki/Hymen
Marburg virus diseaseMarburg virus disease
Weidmann, M.; Mühlberger, E.; Hufert, F. T. (2004). "Rapid detection protocol for filoviruses". Journal of Clinical Virology. ... "Journal of Clinical Microbiology. 40 (7): 2323-2330. doi:10.1128/jcm.40.7.2323-2330.2002. PMC 120575 . PMID 12089242.. ... "Clinical and Vaccine Immunology. 13 (4): 444-451. doi:10.1128/CVI.13.4.444-451.2006. PMC 1459631 . PMID 16603611.. ... "Journal of Clinical Microbiology. 45 (1): 224-226. doi:10.1128/JCM.01893-06. PMC 1828965 . PMID 17079496.. ...
https://en.wikipedia.org/wiki/Marburg_
Inland taipanInland taipan
Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. "Signs and Symptoms of Envenomation: E. Fang ... Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. "Signs and Symptoms of Envenomation: E. Fang ... Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. University of Adelaide. Retrieved October 18, ... Clinical Toxinology Resources. "Oxyuranus microlepidotus -General Details, Taxonomy and Biology, Venom, Clinical Effects, ...
https://en.wikipedia.org/wiki/Inland_taipan
History of intersex surgeryHistory of intersex surgery
... an invited group of clinicians met in Chicago and reviewed clinical evidence and protocols, argued that and adopted a new term ... Large majorities of respondents opposed standard clinical protocols. A 2016 follow-up to the 2006 Consensus Statement, termed a ... There are no controlled clinical trials of the efficacy of early (less than 12 months of age) versus late surgery (in ... Clinical Pediatric and Adolescent Endocrinology.. Philadelphia: Saunders. An example of a now-obsolete recommendation to ...
https://en.wikipedia.org/wiki/History_of_intersex_surgery
Rapid response systemRapid response system
"What stops hospital clinical staff from following protocols? An analysis of the incidence and factors behind the failure of ... These tools can predict clinical deterioration based upon the patient's trait (e.g. has epilepsy) and detect deterioration ... UK National Institute for Health and Clinical Excellence (NICE) (July 2007). "Acutely ill patients in hospital: recognition of ... A RRS consists of two clinical components (afferent and efferent) and two organizational components (process improvement and ...
https://en.wikipedia.org/wiki/Rapid_response_system
Flow-induced dispersion analysisFlow-induced dispersion analysis
Clinical Applications of Capillary Electrophoresis: Methods and Protocols. Methods in Molecular Biology. 1972. New York, NY: ...
https://en.wikipedia.org/wiki/Flow-induced_dispersion_analysis
RetroprogesteroneRetroprogesterone
ISBN 978-94-009-8195-9. Lt Col Pankaj Talwar; Surveen Ghumann Sindhu (18 May 2012). Step by Step: Protocols in Clinical ...
https://en.wikipedia.org/wiki/Retroprogesterone
Investigational New DrugInvestigational New Drug
Clinical trial protocols are the centerpiece of the IND. Detailed protocols for proposed clinical studies to assess whether the ... If the FDA detects a problem, it may place a clinical hold on the IND, prohibiting the start of the clinical studies until the ... Once an IND is submitted, the FDA has 30 days to object to the IND or it automatically becomes effective and clinical trials ... About half of the INDs fail in preclinical and clinical phases of drug development. The FDA runs a medical marijuana IND ...
https://en.wikipedia.org/wiki/Investigational_New_Drug
Taipan pedalaman bahasa Indonesia, ensiklopedia bebasTaipan pedalaman bahasa Indonesia, ensiklopedia bebas
Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. "Signs and Symptoms of Envenomation: E. Fang ... Clinical Toxinology Resources. Snakebite Protocols - Oxyuranus microlepidotus. "Signs and Symptoms of Envenomation: E. Fang ... Clinical Toxinology Resources. "Oxyuranus microlepidotus -General Details, Taxonomy and Biology, Venom, Clinical Effects, ...
https://id.wikipedia.org/wiki/Taipan_pedalaman
母乳哺育 - 维基百科，自由的百科全书母乳哺育 - 维基百科，自由的百科全书
ABM Clinical Protocol #11. （原始内容存档于2006-08-11）.. ... Is maternal opioid use hazardous to breast-fed infants?. Clinical toxicology (Philadelphia, PA). 2012-01, 50 (1): 1-14. PMID ...
https://zh.wikipedia.org/wiki/母乳餵養
AgoraphobiaAgoraphobia
Wyatt, Richard Jed; Chew, Robert H. (2008). Wyatt's Practical Psychiatric Practice: Forms and Protocols for Clinical Use. ... The disappearance of residual and sub-clinical agoraphobic avoidance, and not simply of panic attacks, should be the aim of ... In the social sciences, a perceived clinical bias exists in agoraphobia research. Branches of the social sciences, especially ... Clinical Psychology Review. 30 (1): 37-50. doi:10.1016/j.cpr.2009.08.011. PMID 19775792. "Agoraphobia - Diagnosis and treatment ...
https://en.wikipedia.org/wiki/Agoraphobia
Chiropractic in CanadaChiropractic in Canada
This experience includes clinical assessment, diagnosis, treatment, and referral protocols. The faculty at both CMCC and UQTR ... Candidates must successfully pass Components A and B (Written Cognitive Skills Examination) to be eligible for the Clinical ... Radiology training consists of more than 360 contact hours followed by application during clinical internship. CMCC and UQTR ... Canadian Chiropractic Examining Board requires all candidates to complete a 12-month clinical intership to obtain licensure, as ...
https://en.wikipedia.org/wiki/Chiropractic_in_Canada
Haloperidol decanoateHaloperidol decanoate
Forms and Protocols for Clinical Use. American Psychiatric Pub. pp. 142-. ISBN 978-1-58562-687-8. Katherine M. Fortinash; ... Larsson M, Axelsson R, Forsman A (1984). "On the pharmacokinetics of perphenazine: a clinical study of perphenazine enanthate ... Abstract.). 19th Annual Midyear Clinical Meeting of the American Society of Hospital Pharmacists. Dallas, Texas. Janssen PA, ... The Journal of Clinical Psychiatry. 45 (5 Pt 2): 50-9. PMID 6143748. Curry SH, Whelpton R, de Schepper PJ, Vranckx S, Schiff AA ...
https://en.wikipedia.org/wiki/Haloperidol_decanoate
ThoratecThoratec
MOMENTUM 3 IDE Clinical Study Protocol (HM3). U.S. National Institutes of Health. ClinicalTrials.gov. Retrieved September 16, ... is still in clinical trials for destination therapy. In a two-year randomized controlled clinical trial published in 2009 ... It began undergoing clinical trials in the U.S. and internationally in mid 2014. In mid 2014, CE Mark trials also started for ... It is cleared for clinical use up to six hours, and can be used as a short-term solution to support the circulation while ...
https://en.wikipedia.org/wiki/Thoratec
EMA401EMA401
Spinifex Pharmaceuticals Pty Limited (2011). "CLINICAL STUDY PROTOCOL: Protocol No. EMA401-003". Cite journal requires ,journal ... Spinifex Pharmaceuticals Pty Limited (2011). "CLINICAL STUDY PROTOCOL: Protocol No. EMA401-003". Cite journal requires ,journal ... Spinifex Pharmaceuticals Pty Limited (2011). "CLINICAL STUDY PROTOCOL: Protocol No. EMA401-003". Cite journal requires ,journal ... Phase I clinical trial have indicated that doses of EMA401 up to 400 mg are safe in humans. Spinifex Pharmaceuticals reported ...
https://en.wikipedia.org/wiki/EMA401
Moderna COVID-19 vaccineModerna COVID-19 vaccine
"Clinical Study Protocol mRNA-1273-P301" (PDF). Moderna. COVID-19 Vaccine Moderna assessment report European Medicines Agency " ... The clinical trial is ongoing and is set to conclude in late 2022. In November 2020, Nature reported that "While it's possible ... A review by the FDA in December 2020, of interim results of the Phase III clinical trial on mRNA-1273 showed it to be safe and ... The vaccine in low doses was deemed safe and effective in order to advance a Phase III clinical trial using two 100-μg doses ...
https://en.wikipedia.org/wiki/Moderna_COVID-19_vaccine
Variant of uncertain significanceVariant of uncertain significance
Burke W (April 2014). "Genetic tests: clinical validity and clinical utility". Current Protocols in Human Genetics. 81: 9.15.1- ... The term "variant' is favored in clinical practice over "mutation" because it can be used to describe an allele more precisely ... March 2020). "How Can Law and Policy Advance Quality in Genomic Analysis and Interpretation for Clinical Care?". The Journal of ... As of 2020[update], there continues to be limited involvement from federal agencies to regulate the clinical validity (accuracy ...
https://en.wikipedia.org/wiki/Variant_of_uncertain_significance
Pure tone audiometryPure tone audiometry
Bagatto, M; Moodie, S; Scollie, S; Seewald, R; Moodie, S; Pumford, J; Liu, KP (2005). "Clinical protocols for hearing ... As with most clinical tests, standardized calibration of the test environment, the equipment and the stimuli is needed before ... Although pure-tone audiometry has many clinical benefits, it is not perfect at identifying all losses, such as 'dead regions' ... Handbook of clinical audiology. Katz, Jack., Burkard, Robert, 1953-, Medwetsky, Larry. (5th ed.). Philadelphia: Lippincott ...
https://en.wikipedia.org/wiki/Pure_tone_audiometry
William French AndersonWilliam French Anderson
The clinical protocol began on May 22, 1989, and included 10 patients. The procedure was shown to be safe. Rosenberg went on to ... Only after approval by that formal public governmental review did the gene therapy clinical protocol move on for review by the ... Microinjecting a few non-stem cells was clearly not an efficient procedure for a clinical protocol. In 1984, Anderson published ... Anderson, together with bioethicist John Fletcher, set the ethical standard for this type of clinical protocol in his 1980 ...
https://en.wikipedia.org/wiki/William_French_Anderson
Forensic biologyForensic biology
Postmortem microbiology in sudden death: sampling protocols proposed in different clinical settings. Clinical Microbiology and ... Forensic toxicology is the use of toxicology and other disciplines such as analytical chemistry, pharmacology and clinical ...
https://en.wikipedia.org/wiki/Forensic_biology
Alternative medicineAlternative medicine
"British Journal of Clinical Pharmacology. 54 (6): 577-82. doi:10.1046/j.1365-2125.2002.01699.x. PMC 1874503. PMID 12492603.. ... Research into alternative therapies often fails to follow proper research protocols (such as placebo-controlled trials, blind ... clinical statisticians and pharmacologists, use clinical trials to reveal such effects, allowing physicians to offer a ... "British Medical Journal (Clinical Research Ed.). 287 (6388): 307-08. doi:10.1136/bmj.287.6388.307. PMC 1548588. PMID 6307462. ...
https://en.wikipedia.org/wiki/Integrative_medicine
Quantitative trait locusQuantitative trait locus
"Clinical Genetics: A Self-Study Guide for Health Care Providers. University of South Dakota School of Medicine. Archived from ... Methods and Protocols, Methods in Molecular Biology, Springer US, 2072, pp. 15-25, doi:10.1007/978-1-4939-9865-4_3, ISBN ... Methods and Protocols, Methods in Molecular Biology, Springer US, pp. 15-25, doi:10.1007/978-1-4939-9865-4_3, ISBN ...
https://en.wikipedia.org/wiki/Polygenic_inheritance
Saint Barnabas Medical CenterSaint Barnabas Medical Center
Free clinical education programs are prehospital care, emergency department & hospital programs, and nursing school program. ... and embryo selection protocols. The research achievements from the Institute received both praise and criticism. The works have ...
https://en.wikipedia.org/wiki/Saint_Barnabas_Medical_Center
AcneAcne
Archer CB, Cohen SN, Baron SE (May 2012). "Guidance on the diagnosis and clinical management of acne". Clinical and ... This scale was the first to use a standardized photographic protocol to assess acne severity; since its creation in 1979, the ... Marchetti PM, Barth JH (March 2013). "Clinical biochemistry of dihydrotestosterone". Annals of Clinical Biochemistry. 50 (Pt 2 ... Brandt S (May 2013). "The clinical effects of zinc as a topical or oral agent on the clinical response and pathophysiologic ...
https://en.wikipedia.org/wiki/Acne_vulgaris
Hematopoietic stem cell transplantationHematopoietic stem cell transplantation
Clinical observations[edit]. A study involving 2408 donors (18-60 years) indicated that bone pain (primarily back and hips) as ... 2008). "Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases". JAMA. 299 (8): 925-36 ... Clinical and Experimental Rheumatology. 34 (4 Suppl 98): 53-57. ISSN 0392-856X. PMID 27586805.. ... hepatomegaly and fluid retention are clinical hallmarks of this condition. There is now a greater appreciation of the ...
https://en.wikipedia.org/wiki/Bone_Marrow_Transplant
MedicineMedicine
Clinical laboratory sciences are the clinical diagnostic services that apply laboratory techniques to diagnosis and management ... which allows as much of the available evidence as possible to be collected and analyzed according to standard protocols that ... Subspecialties include transfusion medicine, cellular pathology, clinical chemistry, hematology, clinical microbiology and ... Some related clinical specialties include neurology, neurosurgery and psychiatry.. *Nutrition science (theoretical focus) and ...
https://en.wikipedia.org/wiki/Medical
Cervical cerclageCervical cerclage
... should be used only in the context of a clinical trial or research protocol. While cerclage is generally a safe procedure, ... However, large randomized clinical trials in singleton and twin pregnancies found that the cervical pessary did not result in a ... "The role of cervical pessary placement to prevent preterm birth in clinical practice". American Journal of Obstetrics and ...
https://en.wikipedia.org/wiki/Cervical_cerclage
Genetically modified tomatoGenetically modified tomato
Clinical trials have been conducted on mice using tomatoes expressing antibodies or proteins that stimulate antibody production ... from which to create juice to test in clinical trials on the way to obtaining regulatory approval.[37][38] ...
https://en.wikipedia.org/wiki/Fish_tomato
Smoking banSmoking ban
"Progress in Clinical and Biological Research. 337 (7070): 301-7. doi:10.1136/bmj.313.7070.1450. PMC 2352989. PMID 8973234.. ... "Treatment protocols of the lupus nephritis collaborative study of plasmapheresis in severe lupus nephritis. The Lupus ...
https://en.wikipedia.org/wiki/Anti-smoking_legislation
Lyme diseaseLyme disease
"European Journal of Clinical Chemistry and Clinical Biochemistry (Submitted manuscript). 32 (9): 685-9. doi:10.1515/cclm. ... A two-tiered protocol is recommended by the Centers for Disease Control and Prevention (CDC): the sensitive ELISA test is ... Stanek G, Reiter M (April 2011). "The expanding Lyme Borrelia complex--clinical significance of genomic species?". Clinical ... clinical practice guidelines by the Infectious Diseases Society of America". Clinical Infectious Diseases. 43 (9): 1089-134. ...
https://en.wikipedia.org/wiki/Lyme_disease
ChiropracticChiropractic
"International Journal of Clinical Practice. 66 (10): 940-47. doi:10.1111/j.1742-1241.2012.03004.x. PMC 3506737 . PMID 22994328. ... which relies on a drop table and detailed procedural protocols), Gonstead (which emphasizes evaluating the spine along with ... "Int J Clinical Practice. 64 (8): 1162-65. doi:10.1111/j.1742-1241.2010.02352.x. PMID 20642715.. ... Numerous controlled clinical studies of treatments used by chiropractors have been conducted, with conflicting results.[4] ...
https://en.wikipedia.org/wiki/Chiropractors
RadiographyRadiography
The first use of X-rays under clinical conditions was by John Hall-Edwards in Birmingham, England on 11 January 1896, when he ... "Radiation Doses of Various CT Protocols: a Multicenter Longitudinal Observation Study". Journal of Korean Medical Science. 31 ... "The first clinical X-ray made in America--100 years" (PDF). American Journal of Roentgenology. American Roentgen Ray Society. ... "A clinical audit of anatomical side marker use in a paediatric medical imaging department". Journal of Medical Radiation ...
https://en.wikipedia.org/wiki/X-ray_imaging
Activated carbonActivated carbon
Clinical Chemistry and Laboratory Medicine. 57 (5): 690-696. doi:10.1515/cclm-2018-0967. PMID 30427777.. ... as mobile phase in analytical or preparative protocols. ...
https://en.wikipedia.org/wiki/Activated_charcoal
Fluorescence in situ hybridizationFluorescence in situ hybridization
FISH is often used in clinical studies. If a patient is infected with a suspected pathogen, bacteria, from the patient's ... Fibre FISH protocol from the Human Genome Project at the Sanger Centre ... Hybrid Fusion FISH enables highly multiplexed FISH applications that are targeted within clinical oncology panels. The ... and clinical relevance". Fertility and Sterility. 93 (6): 1892-902. doi:10.1016/j.fertnstert.2008.12.139. PMID 19254793.. ...
https://en.wikipedia.org/wiki/Fluorescence_in_situ_hybridization
ادرار کردن - ویکی‌پدیا، دانشنامهٔ آزادادرار کردن - ویکی‌پدیا، دانشنامهٔ آزاد
Clinical conditions. Many clinical conditions can cause disturbances to normal urination, including:. *Urinary incontinence, ... Steven R. Lindsay (9 January 2008). Handbook of Applied Dog Behavior and Training, Procedures and Protocols. John Wiley & Sons ...
https://fa.wikipedia.org/wiki/ادرار_کردن?match=en
Coomassie Brilliant BlueCoomassie Brilliant Blue
Wittig, I.; Braun, H. P.; Schägger, H. (2006). "Blue native PAGE". Nature Protocols. 1 (1): 418-428. doi:10.1038/nprot.2006.62 ... clinical relevance and in vitro analysis of the function of the outer blood-retinal barrier". Developments in Ophthalmology. ... Pink, M.; Verma, N.; Rettenmeier, A. W.; Schmitz-Spanke, S. (2010). "CBB staining protocol with higher sensitivity and mass ...
https://en.wikipedia.org/wiki/Coomassie_Brilliant_Blue
EndosporeEndospore
Marise A. Hussey, Anne Zayaitz Endospore Stain Protocol Microbe Library (American Society of Microbiology) ... Murray, Patrick R.; Ellen Jo Baron (2003). Manual of Clinical Microbiology. 1. Washington, D.C.: ASM.. .mw-parser-output cite. ...
https://en.wikipedia.org/wiki/Bacterial_spore
Nerve agent - Simple English Wikipedia, the free encyclopediaNerve agent - Simple English Wikipedia, the free encyclopedia
"Soman and sarin: clinical manifestations and treatment of accidental poisoning by organophosphates". Clinical Toxicology 7 (1 ... "1925 Geneva Protocol". United Nations Office for Disarmament Affairs. United Natios. Retrieved February 9, 2016.. ... Geneva Protocol of 1925: This agreement was signed on June 17, 1925, and took effect on February 8, 1928. It permanently bans ... The protocol was extended by the Biological Weapons Convention (1972) and the Chemical Weapons Convention (1993). ...
https://simple.m.wikipedia.org/wiki/Nerve_agent
Bioinformática, a enciclopedia libreBioinformática, a enciclopedia libre
"Journal of Clinical Pathology 50 (5). Páxs. 365-370.. *↑ Craiem, D.; et al. (2008). "New Assessment of Endothelium-Dependent ... 2007). Current Protocols in Bioinformatics (en inglés). Wiley. ISBN 0-471-25093-7.. ... Transmission Control Protocol, Protocolo de control de transmisión) feito por Vinton Cerf e Robert Kahn (1974), un dos ... "Origins of... Image analysis in clinical pathology" ...
https://gl.wikipedia.org/wiki/Bioloxía_computacional
Juris DoctorJuris Doctor
"Protocol School of Washington.. *^ "Summaries of Informal Opinions of the Standing Committee on Professional Ethics". American ... implementing elements such as clinical training, which has become an essential part of legal education in the U.S. and in the J ...
https://en.wikipedia.org/wiki/Juris_doctorate
BioarchaeologyBioarchaeology
Such markers are often based on single cases described in clinical literature in the late nineteenth century. One such marker ... "Evaluating the efficiency of different recording protocols for entheseal changes in regards to expressing activity patterns ...
https://en.wikipedia.org/wiki/Bioarchaeology
Good clinical practiceGood clinical practice
High standards are required in terms of comprehensive documentation for the clinical protocol, record keeping, training, and ... The National Institutes of Health requires NIH-funded clinical investigators and clinical trial staff who are involved in the ... The Medicines for Human Use (Clinical Trials) Regulations 2004. *The Medicines for Human Use (Clinical Trials) Amendment ... clinical trial sponsors, and monitors. In the pharmaceutical industry monitors are often called clinical research associates. ...
https://en.m.wikipedia.org/wiki/Good_clinical_practice
Health professionalHealth professional
These include psychiatrists, psychiatry physician assistants, clinical psychologists, occupational therapists, clinical social ... It is not the intention of this article to explore the protocol of carrying out a proper TB test. A TB blood test for baseline ... These include physiatrists, physician assistants, rehabilitation nurses, clinical nurse specialists, nurse practitioners, ... They include geriatricians, occupational therapists, physician assistants, adult-gerontology nurse practitioners, clinical ...
https://en.wikipedia.org/wiki/Healthcare_professional
Hand transplantationHand transplantation
... is one of only two programs in the United States approved to perform hand/arm transplants using an immunomodulatory protocol, ... group had performed extensive basic science research and feasibility studies for many years prior to their first clinical ...
https://en.wikipedia.org/wiki/Hand_transplantation
Cold Spring Harbor LaboratoryCold Spring Harbor Laboratory
... develop a new clinical cancer research unit at Northwell Health in Lake Success, NY, to support early-phase clinical studies of ... laboratory manuals and protocols, and online services for research preprints.[6] ... "ISIS initiates Phase 3 clinical trials for potential SMA therapy ISIS-SMNrx". The SMA Trust.. ...
https://en.wikipedia.org/wiki/Cold_Spring_Harbor_Laboratory
Aktinium bahasa Indonesia, ensiklopedia bebasAktinium bahasa Indonesia, ensiklopedia bebas
Russell, Pamela J.; Jackson, Paul; Kingsley, Elizabeth Anne (2003), Prostate cancer methods and protocols, Humana Press, hlm. ... Clinical Cancer Research. 10 (13): 4489-97. doi:10.1158/1078-0432.CCR-03-0800 . PMID 15240541.. ...
https://id.wikipedia.org/wiki/Actinium
FluoresceinFluorescein
"Bio-Protocol. 8 (7): e2791. doi:10.21769/bioprotoc.2791.. *^ "The diagnosis and management of anaphylaxis. Joint Task Force on ... The Journal of Allergy and Clinical Immunology. 101 (6 Pt 2): S465-528. 1998. doi:10.1016/S0091-6749(18)30566-9. PMID 9673591. ...
https://en.wikipedia.org/wiki/Fluorescein
Cerebral hypoxiaCerebral hypoxia
a b Richmond, T. S. (May 1997). "Cerebral Resuscitation after Global Brain Ischemia", AACN Clinical Issues 8 (2). Retrieved on ... "The Maryland Medical Protocols for Emergency Medical Services Providers" (PDF).. (1.00 MiB). Maryland Institute for Emergency ... The severity of a neonatal hypoxic-ischaemic brain injury may be assessed using Sarnat staging, which is based on clinical ... Focal cerebral ischemia constitutes a large majority of the clinical cases in stroke pathology with the infarct usually ...
https://en.m.wikipedia.org/wiki/Brain_hypoxia
ଜଳାତଙ୍କ - ଉଇକିପିଡ଼ିଆଜଳାତଙ୍କ - ଉଇକିପିଡ଼ିଆ
Pawan JL (1959). "Rabies in the vampire bat of Trinidad, with special reference to the clinical course and the latency of ... "Milwaukee protocol") କୁହାଗଲା । ଏହି ହାଇପୋଥେସିସ୍ ଅନୁସାରେ ଜଳାତଙ୍କ ଭୁତାଣୁର ମସ୍ତିଷ୍କ ଉପରେ ସ୍ୱଳ୍ପ କାଳୀନ ନଷ୍ଟକାରୀ ପ୍ରଭାବ ରହେ । ଏଣୁ ...
https://or.wikipedia.org/wiki/ଜଳାତଙ୍କ
Lactose intoleranceLactose intolerance
Clinical symptoms typically appear within 30 minutes, but may take up to two hours, depending on other foods and activities.[35 ... The procedure consists of extracting and amplifying DNA from the sample, following with a hybridation protocol in a strip. ... Vandenplas Y (2015). "Lactose intolerance". Asia Pacific Journal of Clinical Nutrition (Review). 24 Suppl 1 (S1): S9-13. doi: ... Lawson M, Bentley D, Lifschitz C (2002). Pediatric gastroenterology and clinical nutrition. London: Remedica. p. 109. ISBN 978- ...
https://en.wikipedia.org/wiki/Lactose_intolerance
Pre-Clinical Models - Techniques and Protocols | Paul C. Guest | SpringerPre-Clinical Models - Techniques and Protocols | Paul C. Guest | Springer
This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models ... Pre-Clinical Models. Book Subtitle. Techniques and Protocols. Editors. * Paul C. Guest ... Authoritative and cutting-edge, Pre-Clinical Models: Techniques and Protocols aims to provide methods that describe the context ... This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models ...
https://www.springer.com/us/book/9781493989935?wt_mc=ThirdParty.SpringerLink.3.EPR653.About_eBook
Standardised Protocols Would Greatly Enhance Clinical And Research Potential Of BTMs - RedorbitStandardised Protocols Would Greatly Enhance Clinical And Research Potential Of BTMs - Redorbit
Standardised Protocols Would Greatly Enhance Clinical And Research Potential Of BTMs. by Sam Savage ... He also noted that standardised protocols would greatly increase the clinical and research potential of BTMs, with improved ... In clinical practice, BTMs are used to monitor osteoporosis treatment. BTMs generally show large and rapid responses to the ... IOF and IFCC experts recommend international reference standards for use of bone turnover markers in clinical studies ...
http://www.redorbit.com/news/science/1971397/standardised_protocols_would_greatly_enhance_clinical_and_research_potential_of/
Protocols and Order Sets | American Association of Clinical EndocrinologistsProtocols and Order Sets | American Association of Clinical Endocrinologists
Posting of these protocols does not constitute endorsement of any specific protocol. We believe that each institution should ... Key Points Successful implementation of protocols requires: Buy-in from key stakeholders (critical care physicians, house staff ... consult with diabetes experts to select and implement insulin protocols. ... AACE Clinical Case Reports *Endocrine Practice - Journal *EmPower Magazine - For Patients *Advertising Opportunities *Clinical ...
https://www.aace.com/disease-state-resources/diabetes/depth-information/protocols-and-order-sets
Clinical Rescue Protocol - 2 - Full Text View - ClinicalTrials.govClinical Rescue Protocol - 2 - Full Text View - ClinicalTrials.gov
Clinical Rescue Protocol - 2. The safety and scientific validity of this study is the responsibility of the study sponsor and ... Treatment effectiveness score as an outcome measure in clinical trials. NIDA Res Monogr. 1997;175:208-20. Review. ... and to determine if blood levels of methadone or buprenorphine correlate with clinical response. ...
https://www.clinicaltrials.gov/ct2/show/NCT00000206
Clinical Trials Protocol Template | grants.nih.govClinical Trials Protocol Template | grants.nih.gov
Home » Policy & Compliance » Clinical Trials » Clinical Trials Protocol Template. Clinical Trials Protocol Template. Applicants ... the NIH and FDA collaboratively developed a Phase 2/3 Clinical Trial Protocol Template and an electronic protocol-writing tool ... To facilitate the development of clinical trial protocols that require a Food and Drug Administration (FDA) Investigational New ... NIH and FDA Release Protocol Template for Phase 2 and 3 IND/IDE Clinical Trials ...
https://grants.nih.gov/node/1230
AG Mednet Announces First Clinical Trial Quality Control Software for QIBA Imaging Protocol ComplianceAG Mednet Announces First Clinical Trial Quality Control Software for QIBA Imaging Protocol Compliance
PRNewswire/ -- Clinical trial sponsors working to standardize the capture and submission of complex imaging data through new ... AG Mednet Announces First Clinical Trial Quality Control Software for QIBA Imaging Protocol Compliance ... to the ever increasing costs and delays of clinical trials. AG Mednets SQC software for QIBA protocols removes the manual ... imaging core labs and clinical research organizations managing clinical trials globally. More than 25,000 registered users ...
https://www.prnewswire.com/news-releases/ag-mednet-announces-first-clinical-trial-quality-control-software-for-qiba-imaging-protocol-compliance-256343291.html
Screening for LID Clinical Studies Unit Healthy Volunteer Protocols - Full Text View - ClinicalTrials.govScreening for LID Clinical Studies Unit Healthy Volunteer Protocols - Full Text View - ClinicalTrials.gov
Screening for LID Clinical Studies Unit Healthy Volunteer Protocols. The safety and scientific validity of this study is the ... To accomplish this objective, up to 5000 participants will be enrolled in this protocol at the NIH Clinical Center clinic or ... The Laboratory of Infectious Diseases (LID) Clinical Studies Unit (CSU) enrolls healthy volunteers into clinical studies to ... NIH Clinical Center Detailed Web Page Publications: Anderson MJ, Heath RB. Cell mediated immunity in experimental influenza and ...
https://clinicaltrials.gov/ct2/show/NCT01386424
LINX Reflux Management System Clinical Study Protocol - Study Results - ClinicalTrials.govLINX Reflux Management System Clinical Study Protocol - Study Results - ClinicalTrials.gov
LINX Reflux Management System Clinical Study Protocol. The safety and scientific validity of this study is the responsibility ... Includes whether analysis was per protocol, intention to treat, or another method. Also provides relevant details such as ... Includes whether analysis was per protocol, intention to treat, or another method. Also provides relevant details such as ...
https://clinicaltrials.gov/ct2/show/results/NCT00776997?sect=X7015&view=results
Frontiers | Editorial: Tumor-Derived Extracellular Vesicles: Protocols, Models, and Clinical Evidence | OncologyFrontiers | Editorial: Tumor-Derived Extracellular Vesicles: Protocols, Models, and Clinical Evidence | Oncology
... new instruments and their related protocols enable the discovery or the improved characterization of bio-objects including ... nanovesicles within the 70-150nm diameter range that have recently aroused a great interest in the scientific and clinical ... Editorial: Tumor-Derived Extracellular Vesicles: Protocols, Models, and Clinical Evidence. Renaud Seigneuric1,2* and Carmen ... Tumor-Derived Extracellular Vesicles: Protocols, Models, and Clinical Evidence. The current frontiers in Oncology are at the ...
https://www.frontiersin.org/articles/10.3389/fonc.2016.00230/full
Developing and implementing computerized protocols for standardization of clinical decisionsDeveloping and implementing computerized protocols for standardization of clinical decisions
... limitation and the availability of extensive information contributes to the varying performance and high error rate of clinical ... Protocols need not be perfect. Several defensible and reasonable approaches are available for clinical problems. However, one ... Developing and implementing computerized protocols for standardization of clinical decisions Ann Intern Med. 2000 Mar 7;132(5): ... including use of the protocols themselves. Computerized protocols for mechanical ventilation and management of intravenous ...
https://pubmed.ncbi.nlm.nih.gov/10691588/?dopt=Abstract
New clinical protocol after general surgery cuts opioid prescribing in half | EurekAlert! Science NewsNew clinical protocol after general surgery cuts opioid prescribing in half | EurekAlert! Science News
... a team of researchers at Lawson Health Research Institute and Western University have developed a new clinical protocol called ... New clinical protocol after general surgery cuts opioid prescribing in half. Lawson Health Research Institute ... A study demonstrating the efficacy of their protocol is being presented at the American College of Surgeons Clinical Congress ... a team of researchers at Lawson Health Research Institute and Western University have developed a new clinical protocol called ...
https://www.eurekalert.org/pub_releases/2018-10/lhri-ncp102418.php
WHO/Europe | Ukraine develops modern and progressive clinical protocol for HIV treatmentWHO/Europe | Ukraine develops modern and progressive clinical protocol for HIV treatment
WHO finalized an international review of a breakthrough clinical protocol for HIV infection in Ukraine that will put the ... Health topics Communicable diseases HIV/AIDS Ukraine develops modern and progressive clinical protocol for HIV treatment ... Ukraine develops modern and progressive clinical protocol for HIV treatment 13-12-2017. WHO finalized an international review ... of a breakthrough clinical protocol for HIV infection in Ukraine that will put the country on the fast track to scaling up HIV ...
http://www.euro.who.int/en/health-topics/communicable-diseases/hivaids/news/news/2017/12/ukraine-develops-modern-and-progressive-clinical-protocol-for-hiv-treatment
Pre-Action Protocol for the Resolution of Clinical DisputesPre-Action Protocol for the Resolution of Clinical Disputes
... ... 2.3 This Protocol does not-. (a) provide any detailed guidance to healthcare providers on clinical risk management or the ... Enforcement of the Protocol and sanctions. 1.7 Where either party fails to comply with this Protocol, the court may impose ... b) the Pre-Action Protocol for Personal Injury Claims;. (c) the Pre-Action Protocol for Low Value Personal Injury Claims in ...
https://www.justice.gov.uk/courts/procedure-rules/civil/protocol/prot_rcd
Modeling Clinical Protocols Using Semantic MediaWiki: The Case of the Oncocure Project | SpringerLinkModeling Clinical Protocols Using Semantic MediaWiki: The Case of the Oncocure Project | SpringerLink
... can improve the adherence of the clinicians to clinical guidelines and protocols. The building of a prescriptive DSS based on ... Eccher C., Ferro A., Seyfang A., Rospocher M., Miksch S. (2009) Modeling Clinical Protocols Using Semantic MediaWiki: The Case ... A computerized Decision Support Systems (DSS) can improve the adherence of the clinicians to clinical guidelines and protocols ... Modeling Clinical Protocols Using Semantic MediaWiki: The Case of the Oncocure Project. ...
https://link.springer.com/chapter/10.1007/978-3-642-03262-2_4?error=cookies_not_supported&code=15026177-eeb6-4378-80e6-a09d10827669
SPIRIT 2013 statement: defining standard protocol items for clinical trialsSPIRIT 2013 statement: defining standard protocol items for clinical trials
However, trial protocols and existing protocol guidelines vary greatly in content and quality. This article describes the ... The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting, and appraisal. ... systematic development and scope of SPIRIT (Standard Protocol Ite … ... for the minimum content of a clinical trial protocol.The 33-item SPIRIT checklist applies to protocols for all clinical trials ...
https://pubmed.ncbi.nlm.nih.gov/23295957/?dopt=Abstract
Paradigms for Clinical fMRI - Current ProtocolsParadigms for Clinical fMRI - Current Protocols
This unit presents description of four basic clinical paradigms for clinical fMRI of language cmprehension, eye movement ( ... This unit presents description of four basic clinical paradigms for clinical fMRI of language cmprehension, eye movement ( ... Comprehensive MRI protocol for stroke management: Tissue sodium concentration as a measure of tissue viability in a non‐human ... primate model and clinical studies. Radiology 139:26‐34. Thulborn, K.R., Martin, C., and Voyvodic, J. 2000. fMRI using a ...
http://www.currentprotocols.com/WileyCDA/CPUnit/refId-mia0603.html
Protocols/Clinical Trials - AIDS Clinical Trials Group - Research - Infectious Disease - Medicine - University of Rochester...Protocols/Clinical Trials - AIDS Clinical Trials Group - Research - Infectious Disease - Medicine - University of Rochester...
Protocols/Clinical Trials Active Studies. Protocol # Protocol Name Status. ACTG A5239. A Pilot Study of Therapy with ...
https://www.urmc.rochester.edu/medicine/infectious-disease/research/protocols.aspx
Evidence-Based Clinical Chelation: A Textbook with Protocols for the ... - Dr. Eleonore Blaurock-Busch, PhD, Dr. Swaran J.S....Evidence-Based Clinical Chelation: A Textbook with Protocols for the ... - Dr. Eleonore Blaurock-Busch, PhD, Dr. Swaran J.S....
It contains specific protocols for the treatment of chronic metal overexposure, all of which are evidence-based, aiding the ... All the protocols listed have been modified for the treatment of chronic metal intoxication, included are oral and intravenous ... The authors explain in simple terms how a chelating agent ́s bioavailability affects metal binding and how various protocols ... such as the Cutler Protocol affect the detoxification process, why DMPS binds mercury and which chelators are useful for the ...
https://books.google.com/books/about/Evidence_Based_Clinical_Chelation.html?id=ZMHoDwAAQBAJ
Pfizer and Astellas Amend Clinical Research Protocols for Two Phase 3 Trials of Enzalutamide in Patients with Hormone-Sensitive...Pfizer and Astellas Amend Clinical Research Protocols for Two Phase 3 Trials of Enzalutamide in Patients with Hormone-Sensitive...
... including unfavorable new clinical data and additional analyses of existing clinical data; the risk that clinical trial data ... Pfizer and Astellas Amend Clinical Research Protocols for Two Phase 3 Trials of Enzalutamide in Patients with Hormone-Sensitive ... amendments to protocols of the ARCHES and EMBARK clinical trials and the expected primary completion dates of those trials, ... Our goal is to build upon the body of clinical evidence for enzalutamide in an effort to help address the unmet needs of an ...
https://www.prnewswire.com/news-releases/pfizer-and-astellas-amend-clinical-research-protocols-for-two-phase-3-trials-of-enzalutamide-in-patients-with-hormone-sensitive-prostate-cancer-300701103.html
Advances in Audiology and Hearing Science: Volume 1: Clinical Protocols and Hearing Devices, 1st Edition (Hardback) - RoutledgeAdvances in Audiology and Hearing Science: Volume 1: Clinical Protocols and Hearing Devices, 1st Edition (Hardback) - Routledge
Part 1: Clinical Protocols Revised. 1. Current and Emerging Clinical Applications of the Auditory Steady-State Response (ASSR) ... Volume 1 primarily focuses on revised clinical protocols and provides information on new research to help guide decisions and ... 9. Clinical Applications of Frequency Following Response in Children and Adults. Milaine Dominici Sanfins, Stavros Hatzopoulos ... 8. Non-Conventional Clinical Applications of Otoacoustic Emissions: From Middle Ear Transfer to Cochlear Homeostasis to Access ...
https://www.routledge.com/Advances-in-Audiology-and-Hearing-Science-Volume-1-Clinical-Protocols/Hatzopoulos/p/book/9781771888288
IRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials | HHS.govIRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials | HHS.gov
Institutional Review Board Review of Protocol and Informed Consent Changes ... Implementing Protocol Changes Affecting Subjects Already Enrolled in a Clinical Trial Prior to Obtaining IRB Approval As noted ... IRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials. September 29, 2008 ... regarding the implementation of changes to protocols and informed consent documents for NCI/CTEP-sponsored clinical trials in a ...
https://www.hhs.gov/ohrp/regulations-and-policy/guidance/september-29-2008-letter-to-dr-jeffrey-abrams/
IRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials | HHS.govIRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials | HHS.gov
Institutional Review Board Review of Protocol and Informed Consent Changes ... Implementing Protocol Changes Affecting Subjects Already Enrolled in a Clinical Trial Prior to Obtaining IRB Approval As noted ... IRB Review of Protocol and Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials. September 29, 2008 ... HHS Home > OHRP > IRB Review of Protocol & Informed Consent Changes for NCI/CTEP-Sponsored Clinical Trials ...
https://www.hhs.gov/ohrp/node/4211
Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis | American Academy of PediatricsEffect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis | American Academy of Pediatrics
Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis. Hugo A. Heij and Martin Offringa ... Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis ... Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis ... Effect of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis ...
https://pediatrics.aappublications.org/content/113/3/626.2
ICON Further Enhances Clinical Trial Feasibility, Protocol Optimisation And Patient Recruitment Capabilities With TriNetX -...ICON Further Enhances Clinical Trial Feasibility, Protocol Optimisation And Patient Recruitment Capabilities With TriNetX -...
ICON Further Enhances Clinical Trial Feasibility, Protocol Optimisation And Patient Recruitment Capabilities With TriNetX. ICON ... TriNetX enables researchers to find the right patients at the right sites for clinical trials. For more information, visit http ... It follows ICONs application of cognitive computing capabilities to clinical trial feasibility and patient recruitment. ICONs ... The company specialises in the strategic development, management and analysis of programs that support clinical development - ...
https://www.thestreet.com/story/13869217/1/icon-further-enhances-clinical-trial-feasibility-protocol-optimisation-and-patient-recruitment-capabilities-with-trinetx.html
Protocol: Phytomedicine-AMARGOL®, Clinical Trial for Efficacy Proof on Therapeutics - Full Text View - ClinicalTrials.govProtocol: Phytomedicine-AMARGOL®, Clinical Trial for Efficacy Proof on Therapeutics - Full Text View - ClinicalTrials.gov
Protocol: Phytomedicine-AMARGOL®, Clinical Trial for Efficacy Proof on Therapeutics (AMARGOL). The safety and scientific ...
https://www.clinicaltrials.gov/ct2/show/NCT01485328
Frontiers | Rehabilitation of Upper Extremity Nerve Injuries Using Surface EMG Biofeedback: Protocols for Clinical Application ...Frontiers | Rehabilitation of Upper Extremity Nerve Injuries Using Surface EMG Biofeedback: Protocols for Clinical Application ...
The aim of this paper was to present structured rehabilitation protocols in two different patient groups with upper extremity ... The rehabilitation protocol for group 1 included guided sEMG training to facilitate initial movements, to increase awareness of ... The rehabilitation protocol for group 1 included guided sEMG training to facilitate initial movements, to increase awareness of ... The aim of this paper was to present structured rehabilitation protocols in two different patient groups with upper extremity ...
https://www.frontiersin.org/articles/10.3389/fnins.2018.00906/full
Standardized protocols would greatly enhance clinical and research potenti... ( An expert working group of the Inter...)Standardized protocols would greatly enhance clinical and research potenti... ( An expert working group of the Inter...)
... protocols,would,greatly,enhance,clinical,and,research,potential,of,BTMs,biological,biology news articles,biology news today, ... In clinical practice BTMs are used to monitor osteoporosis treatment....In its position paper* the Joint IOF-IFCC Bone Marker ... Standardized protocols would greatly enhance clinical and research potential of BTMs. ...An expert working group of the ... Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols. 9. Cold Spring Harbor Protocols features RNA ...
http://bio-medicine.org/biology-news-1/Standardized-protocols-would-greatly-enhance-clinical-and-research-potential-of-BTMs-17072-1/
Anticipating Tensions Between Clinical Care and Study ProtocolAnticipating Tensions Between Clinical Care and Study Protocol
Clinical management. * The Globalization of Clinical Data in Medtech * Noteworthy Clinical Trends in Med Device to Watch in ... In a clinical trial, if they differ from the investigational plan and havent been approved by the Sponsor, theyre protocol ... Anticipating Tensions Between Clinical Care and Study Protocol 3 October, 2017 Laurie Meehan, Social Media Manager; Polaris ... Clinical Solution Overview Clinical Management Trial Master File Trial Software Laboratory QMS TMF Checklist ...
https://www.mastercontrol.com/gxp-lifeline/anticipating-tensions-between-clinical-care-and-study-protocol/
Multiplex PCR Protocol for the Diagnosis of Staphylococcal Infection | Journal of Clinical MicrobiologyMultiplex PCR Protocol for the Diagnosis of Staphylococcal Infection | Journal of Clinical Microbiology
To determine whether our protocol could be used for the direct analysis of clinical samples, we carried out a study in which ... The utility of the protocol for the analysis of clinical samples was verified by analysis of aliquots taken directly from BacT/ ... The utility of our protocol for the direct analysis of clinical samples was tested using samples taken from positive BacT/Alert ... Although we evaluated a number of protocols for the isolation of template DNA, the CTAB protocol was the only one that yielded ...
https://jcm.asm.org/content/39/9/3332?ijkey=8428729bfbcb80322b936a1ed8651512dfc31009&keytype2=tf_ipsecsha
Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol | DiabetesClinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol | Diabetes
Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol. ... Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol ... Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol ... Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol ...
https://diabetes.diabetesjournals.org/content/50/4/710?ijkey=cf11d6b6edd5db39c7d866d3c173c8b18d052cee&keytype2=tf_ipsecsha
TrialsAnalyzing clinical trialTrial protocolsOutcomePreclinical and clinicalAdherenceMethodsPractice2020Deviate from the protocolInvestigatorsJournal of ClinicalStudiesConductEvaluationAssessmentEnrollmentTreatment protocolsImplementationImplicationsVentilator-weaningHigh-dose acetaminophenDevelopment2018GuidelinesParticipantsOncologyCliniciansPharmacologyCentreFeasibilityAcuteEvaluateManagement protocolsSpecimensMaturationStudy ProtocolConclusionsResearch fellowMeasurementDataContent of a clinicalDiagnosisColorectal CancerLaboratoryResultsPopulationsEffectivenessMechanical ventilationEfficacyFacilitatorsRehabilitationFindings25,000PhaseSubjectsFacilitateViralRegulatoryOrganization
Trials57
  • As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
  • It is important to keep in mind that these algorithms have not been directly compared in clinical trials. (aace.com)
  • Treatment effectiveness score as an outcome measure in clinical trials. (clinicaltrials.gov)
  • Applicants conducting phase 2 or 3 clinical trials that require Investigational New Drug applications (IND) or Investigational Device Exemption (IDE) applications can use a NIH-FDA template with instructional and sample text to help write protocols. (nih.gov)
  • The tool provides a suggested format for phase 2 and 3 clinical trials funded by NIH that are being conducted under an FDA IND or IDE Application. (nih.gov)
  • QIBA is an RSNA-sponsored initiative to advance quantitative imaging and the use of imaging biomarkers in clinical trials by reducing variability. (prnewswire.com)
  • Today, the verification and quality assurance of all data submission occurs manually and after the images have been submitted, adding another expense, and opportunity for error, to the ever increasing costs and delays of clinical trials. (prnewswire.com)
  • AG Mednet automates, expedites and improves outcomes in clinical trials by ensuring quality and compliance within critical medical imaging processes. (prnewswire.com)
  • Founded in 2005, AG Mednet is the leading quality compliance partner for image data submission and collection for pharmaceutical, biotechnology and medical device companies, imaging core labs and clinical research organizations managing clinical trials globally. (prnewswire.com)
  • These clinical studies include influenza 'challenge studies' as well as natural history studies and phase I trials involving vaccines for viruses carried by mosquitos such as Zika or Dengue virus. (clinicaltrials.gov)
  • This article describes the systematic development and scope of SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013, a guideline for the minimum content of a clinical trial protocol.The 33-item SPIRIT checklist applies to protocols for all clinical trials and focuses on content rather than format. (nih.gov)
  • Clinical trials / research studies gives a clinician many answers to questions from the point of prevention, detection, diagnosis, control and treatment of illness or a condition such as cancer. (medindia.net)
  • Clinical trials or research is done when there is some reason to believe that the treatment being studied may be valuable to the patient. (medindia.net)
  • Reasons for Premature Conclusion of Late Phase Clinical Trials: An Analysis of ClinicalTrials.gov Registered Phase III Trials. (medindia.net)
  • Investigation of the Influencing Factors on the Incidence of Vertebral Fracture: A Meta-analysis Based on Placebo Data of Randomized Clinical Trials. (medindia.net)
  • Kenji Yasukawa , Ph.D., 'Astellas') today announced amendments to the protocols for two registrational Phase 3 trials, ARCHES and EMBARK, designed to evaluate the safety and efficacy of XTANDI ® (enzalutamide) in men with hormone-sensitive prostate cancer (HSPC). (prnewswire.com)
  • We continually strive to design and implement clinical trials that bring innovations to people with the greatest need,' said Steven Benner , M.D., senior vice president and global therapeutic area head, Oncology Development, Astellas. (prnewswire.com)
  • On April 7, 2008 CTEP issued its first Action Letter under the revised CTEP procedures to investigators conducting CTEP/NCI-sponsored clinical trials involving the use of lapatinib (IND 70252). (hhs.gov)
  • TriNetX enables researchers to find the right patients at the right sites for clinical trials. (thestreet.com)
  • SYNH ), the only fully integrated biopharmaceutical solutions organization, and Protocol First, Inc., a software solutions provider focused on accelerating clinical research, today announced a novel strategic partnership aimed at driving faster, more efficient clinical trials. (benzinga.com)
  • Protocol First has been a leader in developing next-generation technology solutions for complex clinical trials, and we're pleased that we could extend our partnership to improve patients' lives. (benzinga.com)
  • It is a harbinger of the transformation of clinical research to a digital model that ensures end-to-end data traceability in the most complex 'precision medicine' trials, while supporting remote and decentralized study execution," said Hugh P. Levaux, Ph.D., Founder and CEO for Protocol First. (benzinga.com)
  • Protocol First, Inc., founded in 2015 and headquartered in Salt Lake City, UT, develops next-generation technology solutions for complex clinical trials in the Life Sciences industry. (benzinga.com)
  • To facilitate harmonised reporting of outcomes in published trial protocols and reports, the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT) is under development. (bmj.com)
  • The endorsed technical documents are aimed at empowering and developing a critical mass of technical capacity of scientists in Africa to conduct proper clinical trials to ensure quality, safety and efficacy of traditional medicines in line with international standards. (who.int)
  • In addition, the results of this double-blinded clinical trial will shed new light on our understanding of acupuncture point specificity, and development of methodologies in clinical trials of acupuncture treatment. (nih.gov)
  • Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you. (centerwatch.com)
  • Worldwide Clinical Trials is recognized for protocol and feasibility evaluations that are accurate, comprehensive, and insightful. (worldwide.com)
  • Methodological rigor integrated with operational acumen is at the heart of protocol development at Worldwide Clinical Trials. (worldwide.com)
  • We apply it from first-in-man trials and proof-of-concept paradigms through to peri-approval investigations designed to establish a basis for reimbursement decision or highlight clinical attributes of a new product prior to commercialization. (worldwide.com)
  • Worldwide Clinical Trials has access to more than 2,500 validated assays. (worldwide.com)
  • Clinical Trials can do for you. (worldwide.com)
  • Thank you for your interest in Worldwide Clinical Trials. (worldwide.com)
  • This course served as a useful introduction to the issues of translating clinical trials. (proz.com)
  • This website provides access to information from Astellas sponsored clinical trials and the purpose is not to promote or advertise any. (astellas.com)
  • NEW YORK and TOKYO, Aug. 22, 2018 /PRNewswire/ -- Pfizer Inc. (NYSE: PFE) and Astellas Pharma Inc. (TSE: 4503, President and CEO: Kenji Yasukawa, Ph.D., "Astellas") today announced amendments to the protocols for two registrational Phase 3 trials, ARCHES and EMBARK, designed to evaluate the safety and efficacy of XTANDI ® (enzalutamide) in men with hormone-sensitive prostate cancer (HSPC). (astellas.com)
  • Methods Based on a prospectively registered protocol, we systematically reviewed the literature and selected randomised or quasi-randomised controlled trials comparing procalcitonin based protocols to initiate or discontinue antibiotics in patients presenting with AECOPD versus standard care. (bmj.com)
  • Procalcitonin-based protocols used in all included trials were similar. (bmj.com)
  • Clinical trial managers historically relied on internal experience to determine how much to pay physicians for performing clinical trials. (marketwired.com)
  • Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. (clinicalconnection.com)
  • Learn more about clinical research and participating in a study at About Clinical Trials . (clinicalconnection.com)
  • ClinicalConnection.com is a resource that provides information on clinical trials and other research opportunities worldwide. (clinicalconnection.com)
  • Cancer is currently the second leading cause of death in the USA, however many gains are being made in cancer therapeutics due in large part to patient participation in clinical trials. (aacrjournals.org)
  • A review of blood pressure measurement protocols among hypertension trials: implications for "evidence-based" clinical practice. (g-i-n.net)
  • Time to initiation of weaning trials was 2 ICU days in the nurse-driven protocol group, whereas it was 3 days in the physician group. (freecme.com)
  • A majority of previous studies on weaning protocols have examined respiratory therapists taking responsibility or ICU physicians directing weaning trials. (freecme.com)
  • To provide focused interactive training in ADRD clinical trials to a diverse cadre of investigators. (springer.com)
  • The Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD) is a novel multidisciplinary clinical trial training program funded by the National Institute on Aging and the Alzheimer's Association with two educational tracks. (springer.com)
  • The Fellowship track includes current and future principal investigators and focuses on the design, conduct and analysis of ADRD clinical trials. (springer.com)
  • K ey to the US National Plan to Address Alzheimer's Disease and Related Dementias (ADRD) will be clinical trials of therapies that are capable of slowing or preventing the onset of symptoms ( 1 ). (springer.com)
  • Diversifying study teams is a core component of the mission of the Alzheimer's Clinical Trials Consortium (ACTC). (springer.com)
  • The ACTC's Inclusion, Diversity, and Education in Alzheimer's disease Clinical Trials (IDEA-CT) Committee is charged with developing goals, formulating a strategic plan, and serving as a source of oversight to support the ACTC's core values of inclusion, diversity and training in ADRD clinical trials. (springer.com)
  • To address these needs and goals, members of the ACTC IDEA-CT committee developed the Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD). (springer.com)
  • Working independently and under general supervision, the Clinical Trial Protocol Coordinator will support their department/trial(s) in the administrative day to day project activities of TIMI trials (both nationally and internationally) following good clinical practices, regulatory requirements and sponsors/TIMI standards to ensure compliance for the TIMI Study Group. (americasjobexchange.com)
  • Two randomized double-blind clinical trials in patients with acute ischemic stroke have shown that treatment with a daily dose of 6 g acetaminophen (paracetamol) results in a small but rapid and potentially worthwhile reduction of 0.3°C (95% CI: 0.1-0.5) in body temperature. (pubmedcentralcanada.ca)
  • We conducted two randomized, placebo-controlled clinical trials to study whether early treatment with acetaminophen reduces body temperature in patients with acute ischemic stroke confined to the carotid territory. (pubmedcentralcanada.ca)
  • Collette Lindley, Research Assistant at the SRC stated: "Our validated methods for clinical trials require a large throughput of growth media types and dilution replicates with up to 16 spiral plates for each subject for each study visit. (selectscience.net)
Analyzing clinical trial1
  • Combining these approaches allows the companies to address customer nuances related to trial protocols, capturing and analyzing clinical trial data faster and more efficiently with the goal of accelerating product time-to-market. (benzinga.com)
Trial protocols2
  • To facilitate the development of clinical trial protocols that require a Food and Drug Administration (FDA) Investigational New Drug (IND) or Investigational Device Exemption (IDE) Application, the NIH and FDA collaboratively developed a Phase 2/3 Clinical Trial Protocol Template and an electronic protocol-writing tool to help investigators think through the scientific basis of their assumptions, minimize uncertainty in the interpretation of outcomes, and prevent loss of data. (nih.gov)
  • However, trial protocols and existing protocol guidelines vary greatly in content and quality. (nih.gov)
Outcome4
  • This Protocol encourages a cards-on-the-table approach when something has gone wrong with a claimant's treatment or the claimant is dissatisfied with that treatment and/or the outcome. (justice.gov.uk)
  • Some studies showed that children with myeloid-positive ALL had a poorer clinical outcome compared with those of myeloid-negative ALL patients [ 10 , 18 , 19 ]. (hindawi.com)
  • Taken one step further, risk is minimized by helping ensure patient safety and outcome through proper application of appropriate standards of care (effective protocols) and good clinical judgment (effective training) by competent clinicians (effective hiring) using safe equipment (effective fleet and equipment maintenance). (emergencydispatch.org)
  • In the original protocol, the primary outcome measure is a dichotomized score on the modified Rankin Scale (mRS) [ 2 ] assessed at 3 months from onset of symptoms, with good functional outcome defined as a score of 0-2 and poor functional outcome as a score of 3-death. (pubmedcentralcanada.ca)
Preclinical and clinical2
  • Electroporation Protocols: Preclinical and Clinical Gene Medicine, Second Edition provides in-depth knowledge on the delivery of naked DNA and small-interfering RNA (siRNA) to the targeted cells, tissues, and animals for prevention and treatment of disease. (mexmat.ru)
  • Ibudilast's anti-neuroinflammatory and neuroprotective actions have been demonstrated in preclinical and clinical study results and provide the rationale for its potential therapeutic utility in neurodegenerative diseases (e.g., progressive MS and ALS), substance abuse/addiction and chronic neuropathic pain. (cnbc.com)
Adherence2
  • He also noted that standardised protocols would greatly increase the clinical and research potential of BTMs, with improved value in patient management and other uses, such as prediction of the rate of bone loss, identification of secondary osteoporosis, prediction of response to therapy, and in improving treatment adherence. (redorbit.com)
  • A computerized Decision Support Systems (DSS) can improve the adherence of the clinicians to clinical guidelines and protocols. (springer.com)
Methods8
  • Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. (springer.com)
  • Authoritative and cutting-edge, Pre-Clinical Models: Techniques and Protocols aims to provide methods that describe the context of specific disease or therapeutic areas. (springer.com)
  • Protocols in Biochemistry and Clinical Biochemistry offers clear, applied instruction to fundamental biochemistry methods and protocols, from buffer preparation to nucleic acid purification, protein, lipid, carbohydrate, and enzyme testing, and clinical testing of vitamins, glucose and cholesterol levels, among other diagnostics. (researchandmarkets.com)
  • Each protocol is illustrated with step-by-step instructions, labeled diagrams, and color images, as well as a thorough overview of materials and equipment, precursor techniques, safety considerations and standards, analysis and statistics, alternative methods and troubleshooting. (researchandmarkets.com)
  • MATERIALS AND METHODS This longitudinal human clinical trial is designed as a prospective study, to measure implant stability with the resonance frequency analyzer (Osstell, Integration Diagnostics AB, Sweden) at time of implant placement and up to 16 weeks post placement. (clinicaltrials.gov)
  • The study reviews all of the generally accepted clinical analytical methods that are currently in use today for measuring HbA1c levels. (prnewswire.co.uk)
  • Methods Seventy-five football players with an acute hamstring injury, verified by MRI, were randomly assigned to one of two rehabilitation protocols. (bmj.com)
  • METHODS: Subjects were alternately allocated management according to one of two protocols: one without (group A) and one with (group B) immediate access to results of basic laboratory tests. (bmj.com)
Practice13
  • In clinical practice, BTMs are used to monitor osteoporosis treatment. (redorbit.com)
  • Professor John Kanis, IOF President, urged the adoption of the reference standards by the scientific community, "Without precluding the use of other BTMs, the adoption of these reference standards would facilitate comparison between studies and allow data from different studies to be pooled in order to facilitate their incorporation into routine clinical practice. (redorbit.com)
  • Clinical endocrinologists worldwide rely on Endocrine Practice, the official journal of the American Association of Clinical Endocrinologists (AACE), to keep them on the leading edge of treatment of patients with endocrine diseases. (aace.com)
  • Members of AACE are physicians with special education, training and interest in the practice of clinical endocrinology. (aace.com)
  • Variation in clinical practice is due in part to clinicians' poor compliance with guidelines and recommended therapies. (nih.gov)
  • It is not likely to be concerned with minor or technical shortcomings (see paragraph 4.3 to 4.5 of the Practice Direction on Pre-Action Conduct and Protocols). (justice.gov.uk)
  • Protocol trumps practice. (mastercontrol.com)
  • When deciding whether or not to conduct a particular study, a PI needs to verify that the protocol is aligned with practice norms. (mastercontrol.com)
  • This protocol will provide greater support to their practice and to contribute to the early detection of precursor lesions and consequent decrease of the incidence of cervical cancer, as well as promote a better quality of care to clients. (scielo.br)
  • At this time, Advanced Practice Registered Nurse (APRN) clinicals cannot be substituted with virtual assignments, so clinical hours will need to be arranged with the faculty and assignments will be based on space availability. (oakland.edu)
  • First, it may not correspond with everyday clinical practice. (pubmedcentralcanada.ca)
  • Her main research interests include cultural differences in illness presentations, cognitive profiles in eating disorders, and experimental work in emotion processing and translational research from experimental findings to real clinical practice. (wikipedia.org)
  • Tchanturia's research primarily concerns the cognitive and socio-emotional aspects of eating disorders, implementing positive psychology in clinical practice. (wikipedia.org)
20201
  • With these changes, the estimated primary completion date for the EMBARK clinical trial is mid-2020. (prnewswire.com)
Deviate from the protocol2
  • Researchers blur the distinction themselves when they conduct procedures that are consistent with clinical care but deviate from the protocol. (mastercontrol.com)
  • All studies were open-labelled or single blinded and the final decision to administer or withhold antibiotic was left to the responsible clinician, who could deviate from the protocol. (bmj.com)
Investigators6
  • For more information about AG Mednet's SQC for QIBA and its work with clinical research organizations, imaging trial sponsors, imaging core labs and principal investigators, please visit www.agmednet.com . (prnewswire.com)
  • This study is a collaborative effort between MediciNova, Inc. and Drs. Nazem Atassi and Haruhiko Banno, Principal Investigators at Massachusetts General Hospital's (MGH) Neurological Clinical Research Institute (NCRI) and Harvard Medical School to measure the effects of MN-166 on reducing brain microglial activation utilizing a biomarker in 15 subjects with ALS. (cnbc.com)
  • The Sunshine Act has changed how companies and trial managers pay clinical investigators," said Ryan McGuire, Head of Research at Cutting Edge Information. (marketwired.com)
  • It also examines common milestone payments, the number of payments made to clinical investigators and ranges and averages of direct costs that investigators often pass through to sponsors. (marketwired.com)
  • In addition, the investigators were wise to survey the intensivists who staff this ICU on their perceptions of the nurse-managed weaning protocol since they ultimately gave the "green light" to proceed with extubation. (freecme.com)
  • The low availability of ADRD trialists, including clinical investigators, statisticians, and other experts represents a threat to the national ADRD research agenda. (springer.com)
Journal of Clinical2
  • Thank you for sharing this Journal of Clinical Microbiology article. (asm.org)
  • Message Body (Your Name) thought you would be interested in this article in Journal of Clinical Microbiology. (asm.org)
Studies20
  • More importantly, it identifies research priorities and recommends that specific markers be used as reference analytes for BTMs in clinical and observational studies. (redorbit.com)
  • It recommends that specific markers of bone formation (s-PINP) and of bone resorption (s-CTX) be used as reference analytes for bone turnover markers in clinical and observational studies. (redorbit.com)
  • Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. (clinicaltrials.gov)
  • The Laboratory of Infectious Diseases (LID) Clinical Studies Unit (CSU) enrolls healthy volunteers into clinical studies to study infectious diseases. (clinicaltrials.gov)
  • The LID CSU performs clinical studies to learn about these viral infections and assist in the development of vaccines and treatments for the infections. (clinicaltrials.gov)
  • Previous human challenge studies have addressed some aspects of the natural history by evaluating the timing of viral replication, shedding, clinical symptoms, and innate and adaptive immune responses. (clinicaltrials.gov)
  • While initially the protocol was designed to screen participants for influenza challenge studies, we have expanded our scope of research to include emerging and re-emerging infectious diseases.The primary goal of this study is to collect and store serum and RNA samples and obtain clinical and laboratory data from volunteers to determine in advance if they are potentially eligible to participate in future clinical studies. (clinicaltrials.gov)
  • To accomplish this objective, up to 5000 participants will be enrolled in this protocol at the NIH Clinical Center clinic or day hospital in order to maintain a pool of participants who have been evaluated and can be screened for future LID Clinical Studies protocols. (clinicaltrials.gov)
  • Computerized protocols for mechanical ventilation and management of intravenous fluid and hemodynamic factors in patients with the acute respiratory distress syndrome provide case studies for this discussion. (nih.gov)
  • Comprehensive MRI protocol for stroke management: Tissue sodium concentration as a measure of tissue viability in a non‐human primate model and clinical studies. (currentprotocols.com)
  • Seizure occurred in 0.4% of patients receiving XTANDI in clinical studies. (prnewswire.com)
  • Apparent dramatic reductions were achieved in both parameters by performing imaging studies in all patients with equivocal clinical findings. (aappublications.org)
  • The company specialises in the strategic development, management and analysis of programs that support clinical development - from compound selection to Phase I-IV clinical studies. (thestreet.com)
  • Clinical protocols for osteopathic manipulative treatment (OMT) procedures have been used in "technique" studies to examine the effects of specific procedures. (jaoa.org)
  • In my opinion, in technique studies based on protocols for OMT procedures, manipulations are not delivered in a manner consistent with osteopathic principles, and there may be unforeseen consequences of such research-whether findings for the procedures are positive or negative. (jaoa.org)
  • This TUViD-VM protocol can be used in metagenomic and virome studies to increase the likelihood of detecting viruses from any biological source. (cdc.gov)
  • The discrepancies between studies may be related to the use of different treatment protocols [ 20 ], different populations, as well as different definition criteria of myeloid-positive ALL, which are summarized in Table 1 . (hindawi.com)
  • Few studies to date have evaluated the effectiveness of different treatment protocols for acute hamstring injuries in athletes. (bmj.com)
  • In addition to spiral plates for clinical studies, we also use pour plates and filtration membranes in our in vitro studies. (selectscience.net)
  • Based on findings from their qualitative studies that mapped out the needs for the three stakeholders, Tchanturia and colleagues collaboratively engaged people with lived experience, carers, and clinicians from the National Eating Disorder Service to develop the PEACE clinical pathway. (wikipedia.org)
Conduct7
  • 1.4 This Protocol is now regarded by the courts as setting the standard of normal reasonable pre-action conduct for the resolution of clinical disputes. (justice.gov.uk)
  • 1.5.1 This Protocol sets out the conduct that prospective parties would normally be expected to follow prior to the commencement of any proceedings. (justice.gov.uk)
  • The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting, and appraisal. (nih.gov)
  • The study protocol refers to the 'recipe' used to conduct a study des. (bio-medicine.org)
  • The study protocol refers to the 'recipe' used to conduct a study, describes what will be done during the study, how this will be done and why it is being done. (bio-medicine.org)
  • Advise sites on protocol conduct, interpretation of protocols and ensures resolution of issues as applicable per department/trial. (americasjobexchange.com)
  • Demonstrate and maintain knowledge of regulations, clinical research conduct, laws, guidelines and standards relating to department/trial(s). (americasjobexchange.com)
Evaluation5
  • This reasoning is the basis of an explicit method of decision support that allows the rigorous evaluation of interventions, including use of the protocols themselves. (nih.gov)
  • We are very pleased that this important regulatory step is now completed as we can continue clinical evaluation of MN-166 in the treatment of ALS. (cnbc.com)
  • Evaluation of the clinical and economic impact after the protocol change of basiliximab use in orthohepatic transplant. (isciii.es)
  • EISS implemented an evaluation protocol to assess the quality of clinical data collected by sentinel networks for the surveillance of influenza. (eurosurveillance.org)
  • Evaluation of two clinical protocols for the management of women with vaginal discharge in southern Thailand. (bmj.com)
Assessment3
  • Using data from eight Community Care Access Centres (CCACs) in Ontario, we demonstrate that an automatic, data-driven, machine learning algorithm such as the K nearest neighbors (KNN) algorithm can predict rehabil itation potential more effectively than the current Clini cal Assessment Protocol (CAP). (actapress.com)
  • Full clinical assessment including speculum examination and microbiological assessment for infection with gonorrhoea, chlamydia, candida, trichomonas, and bacterial vaginosis was performed on all women. (bmj.com)
  • Follow up assessment of clinical and microbiological response was performed 1-2 weeks later. (bmj.com)
Enrollment4
  • As you know, on March 20, 2008 CTEP issued a memorandum to NCI/CTEP-sponsored cooperative groups explaining implementation of revised CTEP procedures for handling amendments to cooperative group protocols and enrollment of new subjects in these protocols in situations in which new or modified risk information is considered to represent no more than a minor alteration in the overall risk-benefit relationship for subjects. (hhs.gov)
  • whether suspensions of new subject enrollment by CTEP pending IRB approval of protocol and informed consent document changes need to be reported to OHRP. (hhs.gov)
  • To inform understanding of the potential efficacy and safety of hydroxychloroquine-azithromycin, we strongly advocate for enrollment of all patients who are candidates into IRB-approved clinical research protocols. (acc.org)
  • We hypothesize that a provider-directed intervention will increase rates of cancer clinical trial enrollment amongst African-Americans. (aacrjournals.org)
Treatment protocols2
  • The building of a prescriptive DSS based on breast cancer treatment protocols and its integration with a legacy Electronic Patient Record is the aim of the Oncocure project. (springer.com)
  • Failure of bedside hospital clinical staff to follow established treatment protocols has been identified as a common factor in patients having an adverse event during their hospitalisation. (bmj.com)
Implementation3
  • Dr. Ken Leslie, scientist at Lawson, associate professor in the Department of Surgery at Schulich Medicine & Dentistry, and Chair/Chief of the Division of General Surgery at London Health Sciences Centre led the implementation of the new protocol. (eurekalert.org)
  • Implementation of a nurse-driven protocol for weaning patients resulted in shortened duration of mechanical ventilation, shorter ICU stays, and a higher rate of successful weaning, with ICU physicians reporting a generally positive attitude toward nurses being responsible for protocol-directed weaning. (freecme.com)
  • The nurses participated in protocol training and education sessions prior to implementation of the protocol, with a 1-month pilot period to gain familiarity with the protocol and to standardize communication with physicians. (freecme.com)
Implications2
  • No protocol or proposed program is recommended without full knowledge of the logistical and financial implications in addition to the clinical and regulatory implications. (worldwide.com)
  • Implications for clinical decision-making and computerized health information sys tems are discussed. (actapress.com)
Ventilator-weaning1
  • A prospective study design was used to compare retrospective data from a specific 6-month period of physician-directed weaning outcomes with patient outcomes during a 6-month prospective period of the nurse-driven ventilator weaning protocol. (freecme.com)
High-dose acetaminophen2
  • Paracetamol (Acetaminophen) In Stroke (PAIS) is a randomized, double-blind clinical trial, comparing high-dose acetaminophen with placebo in 2500 patients. (pubmedcentralcanada.ca)
  • The Paracetamol (Acetaminophen) In Stroke (PAIS) study is a phase III multicenter, double blind, randomized, placebo-controlled clinical trial of high-dose acetaminophen in patients with acute stroke. (pubmedcentralcanada.ca)
Development7
  • This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models in a number of medical areas, including metabolic disorders, longevity, cancer, heart disease and psychiatric disorders. (springer.com)
  • ICON's use of TriNetX is a further example of our commitment to deploy industry-leading technologies that help customers overcome complex clinical development challenges. (thestreet.com)
  • The present study has led to the development of a dynamic pre-clinical testing protocol to quantitatively assess the efficacy of disc replacement devices. (bl.uk)
  • Additionally, the spine simulator and testing protocol would provide valuable data during the design stage of new total disc replacements, aiding the development of the next generation of artificial discs. (bl.uk)
  • Feasibility data is analyzed, summarized and graphically presented in an executive summary document that provides supporting data and facts clearly, to assist the optimal development of your clinical research program. (worldwide.com)
  • The report is a valuable resource for clinical development managers, directors and vice presidents to stay informed on the latest trends around determining clinical investigator FMV. (marketwired.com)
  • Findings from literature and market research guided towards the development of a standardized glucose measurementtransmission protocol using a middleware. (joanneum.at)
20181
  • The companies now anticipate the primary completion date for the ARCHES clinical trial to be in late 2018. (prnewswire.com)
Guidelines4
  • Computerized protocols used to deliver decision support can be configured to contain much more detail than textual guidelines or paper-based flow diagrams. (nih.gov)
  • Computer-Based Medical Guidelines and Protocols: A Primer and Current Trends. (springer.com)
  • The recommendations will be taken into account during the WHO Regional Office for Europe-initiated revision of its 2007 HIV/AIDS clinical guidelines for the WHO European Region, based on revised global WHO recommendations on ART for adults and adolescents, ART for infants and children, use of ARVs for treatment of HIV-infected pregnant women and infants born to them. (who.int)
  • Conclusions Good compliance with UK guidelines for tryptase measurements is achievable in this long-term cohort, but obtaining clinical details at referral remains a challenge. (bmj.com)
Participants2
  • But as a researcher, I feel like it's up to me to make sure patients feel empowered as participants in my clinical trial. (ehealthinnovation.org)
  • African-Americans are underrepresented amongst cancer clinical trial participants, despite evidence from our institution that African-Americans were more than twice as likely as Caucasians to enroll in a cancer clinical trial when offered. (aacrjournals.org)
Oncology2
  • In order to identify potential intervention strategies, we surveyed staff in the Section of Hematology/Oncology at the University of Chicago regarding clinical trial accrual. (aacrjournals.org)
  • A short, seven question, survey was distributed to all employees in the Section of Hematology/Oncology who were directly involved in clinical care or research. (aacrjournals.org)
Clinicians1
  • however, clinicians must be willing to modify personal styles of clinical management. (nih.gov)
Pharmacology1
  • Clinical pharmacology has changed many clinical systems, including anaesthesia delivery in both the hospital and ambulatory surgery settings. (termedia.pl)
Centre3
  • The six-month single-centre, single-blinded, controlled switching study with periods of clinical confinement is being conducted in Germany. (bio-medicine.org)
  • Synbiosis, a world-leading manufacturer of automated micro-biological systems, today announced its ProtoCOL automated colony counter is being successfully used by the Skin Research Centre (SRC) at the University of Leeds, one of Europe's leading dermatology centres, to rapidly test the effectiveness of new anti-microbial therapies to treat acne, dermatitis and other skin diseases. (selectscience.net)
  • Martin Smith for Synbiosis commented:" We are delighted so see the ProtoCOL being used routinely at such a major dermatology centre as the SRC. (selectscience.net)
Feasibility2
  • It follows ICON's application of cognitive computing capabilities to clinical trial feasibility and patient recruitment . (thestreet.com)
  • Feasibility of the rehabilitation protocols for the two different patient populations was illustrated. (frontiersin.org)
Acute5
  • Objective To characterise the clinical features of patients admitted to hospital with coronavirus disease 2019 (covid-19) in the United Kingdom during the growth phase of the first wave of this outbreak who were enrolled in the International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) World Health Organization (WHO) Clinical Characterisation Protocol UK (CCP-UK) study, and to explore risk factors associated with mortality in hospital. (bmj.com)
  • The clinical experience of human immunodeficiency virus (HIV) + patients treated with oral atovaquone for acute Pneumocytstis carinii pneumonia (PCP) under a Treatment Investigational New Drug (IND) protocol (mild or moderate PCP) and an Open-Label Study protocol (severe PCP) was evaluated. (rti.org)
  • Objective To compare the effectiveness of two rehabilitation protocols after acute hamstring injury in Swedish elite football players by evaluating time needed to return to full participation in football team-training and availability for match selection. (bmj.com)
  • There is a lack of clinical research and consensus regarding the effectiveness of various rehabilitation protocols for acute hamstring injuries in football. (bmj.com)
  • Results 98% provided two or more acute samples, but only 60% supplied clinical information. (bmj.com)
Evaluate4
  • For the final step, four judges were selected to evaluate the clinical protocol according to AGREE 2. (scielo.br)
  • The primary objective of the study will be to evaluate the effects of CSP-1103 compared to placebo on clinical decline in subjects with MCI due to AD and who are also positive for amyloid β (Aβ) biomarker. (cnbc.com)
  • 1 The quality of published research affects the ability of researchers and stakeholders to evaluate, replicate and build on study findings, which in turn impacts evidence-based clinical and policy decision making. (bmj.com)
  • Now, however, companies evaluate a variety of factors including industry benchmarks, historic payment data and trial protocol details. (marketwired.com)
Management protocols3
  • DESIGN: Alternate allocation of subjects to one of two management protocols. (bmj.com)
  • The National Task Force on Covid-19 has decided against including Itolizumab drug in clinical management protocols for treating the disease even though the DCGI has approved its 'restricted emergency use' in infected patients, official sources said. (business-standard.com)
  • A majority of the members of the task force opined that there was not enough evidence currently to get the drug included in the clinical management protocols for Covid-19,' said an official source. (business-standard.com)
Specimens3
  • Based on the preceding discussion, the most important considerations with respect to the diagnosis of staphylococcal infections are (i) identification of staphylococci in clinical specimens, (ii) differentiation of S. aureus from the less-pathogenic CNS, and (iii) determination of whether isolates of either group are resistant to oxacillin. (asm.org)
  • However, for clinical specimens, such as blood, other fluids, or infected organ tissues, successful detection of viruses is less likely because virus-to-host genome ratios are insufficient ( 3 - 6 ). (cdc.gov)
  • Analysis of bronchoalveolar lavage specimens from immunocompromised patients with a protocol applicable in the microbiology laboratory. (asm.org)
Maturation3
  • This research topic aims at providing recent findings and reviews to contribute to the maturation of this emerging field with high clinical potential. (frontiersin.org)
  • We improved the capacity of clinical-grade monocyte-derived dendritic cells to elaborate IL-12 with special regard of their state of maturation, different maturation stimuli and its regulation by TH1/TH2-influencing cytokines. (egms.de)
  • All investigated clinical-grade protocols for maturation of monocyte-derived DC appeared able to provide the phenotypic characteristics necessary to initiate DC maturation. (egms.de)
Study Protocol3
  • Any GCP course worth its registration fee will discuss the distinction between standard of care and the study protocol. (mastercontrol.com)
  • The SPA request includes the proposed Phase III study protocol, statistical analysis plans and briefing materials along with specific questions from CereSpir to facilitate a meaningful dialogue with the FDA on the proposed study design. (cnbc.com)
  • Transcutaneous vagus nerve stimulation for the treatment of depression: a study protocol for a double blinded randomized clinical trial. (nih.gov)
Conclusions3
  • Conclusions A rehabilitation protocol emphasising lengthening type of exercises is more effective than a protocol containing conventional exercises in promoting time to return in Swedish elite football. (bmj.com)
  • CONCLUSIONS: Both protocols were equally effective in managing women with abnormal vaginal discharge. (bmj.com)
  • Conclusions Despite an organisational commitment to the RRS, clinical staff act on local cultural rules within the clinical environment that are usually not explicit. (bmj.com)
Research fellow2
  • After relocating to London in 1997, she became a clinical research fellow at the Institute of Psychiatry, King's College London in 1998. (wikipedia.org)
  • After relocating to the United Kingdom, Tchanturia worked as a Clinical Research Fellow at Institute of Psychiatry, Psychology and Neuroscience, King's College London from 1998-2003. (wikipedia.org)
Measurement3
  • Moreover, it examines clinical measurement devices and reagents as utilized in hospitals, clinics, doctor's offices and at-home care locations. (prnewswire.co.uk)
  • Aim was to develop a prototype of an automated glucose measurement transmission protocol based on the Continua DesignGuidelines and to embed the protocol into a CDSS used by healthcare professionals. (joanneum.at)
  • A literature and market research was performed to analyze the state-of-the-art and thereupon develop, integrate and validate an automated glucose measurement transmission protocol in an iterative process. (joanneum.at)
Data16
  • BOSTON , April 23, 2014 /PRNewswire/ -- Clinical trial sponsors working to standardize the capture and submission of complex imaging data through new QIBA imaging charters now have an easy and effective way to ensure the protocols are being met. (prnewswire.com)
  • AG Mednet's Submission, Quality and Compliance (SQC) software for QIBA is the first technology to automate the process of verifying QIBA protocol compliance, saving sponsors time and money and making it easier for investigator sites to submit quality data. (prnewswire.com)
  • AG Mednet's SQC software for QIBA protocols removes the manual process and scans imaging data for QIBA compliance in a fraction of the time, at a fraction of the cost. (prnewswire.com)
  • AG Mednet provides the market-leading functionality and support to collect clinical trial image data globally, apply advanced, automated quality-assurance processes to ensure the data is protocol-compliant and readily usable, properly de-identify it to ensure regulatory compliance, and deliver it reliably and securely to one or more trial repositories. (prnewswire.com)
  • When we looked at the data from this new protocol, we saw that the patient's pain-control was just as good with this pathway, without a huge prescription for narcotics. (eurekalert.org)
  • Each data point in the TriNetX system can be traced to healthcare organisations who have the ability to identify individual patients, enabling ICON to develop virtual patient cohorts that can be found in real-world clinical trial settings. (thestreet.com)
  • The partnership is expected to optimize data integration with Electronic Health Record Systems and support Remote Source Data Review, further extending a multi-year, pre-existing relationship between Syneos Health and Protocol First. (benzinga.com)
  • The collaboration responds to the increasing demand from biopharmaceutical customers for digital solutions that break down silos between Sites, Sponsors, CROs and functional areas to accelerate the collection and review of clinical trial research data. (benzinga.com)
  • The enhanced collaboration furthers the ability of Syneos Health to combine Protocol First's proprietary software solutions that integrate data from leading EHR systems into electronic data capture (EDC) with operational insights from Syneos Health Dynamic Assembly ® network - an open ecosystem of best-of-breed data and technology collaborators - to deliver fit-for-purpose customer solutions. (benzinga.com)
  • How are mutational data helping inform clinical prognosis and treatment protocol? (ajmc.com)
  • The Phase 2 clinical program generated preliminary safety and efficacy data in approximately 100 people, half of whom received CSP-1103 for up to 2 years. (cnbc.com)
  • These two separate cohorts are included in one single protocol to enable patient data from these two groups to be entered into a common database, as the current prognostic classifications determining treatment may evolve further with subsequent more detailed molecular analysis of the tumours. (centerwatch.com)
  • Also, there are some differences between the beam quality specifiers and data proposed by the two protocols. (oregonstate.edu)
  • The TG-51 protocol allows the determination of a more accurate absorbed dose in a ⁶⁰Co beam than the TG-21 protocol since it uses an absorbed dose-to-water calibration factor directly measured, while the exposure based dosimetry system is dependent on external physical data which are not measured in clinics. (oregonstate.edu)
  • A fast and accurate data transmission from glucose meter to clinical decision support systems (CDSSs) is crucial for the management of type 2 diabetes mellitus since almost all therapeutic interventions are derived from glucose measurements. (joanneum.at)
  • Our clinical trial data is also subject to audit by regulatory authorities at any time. (selectscience.net)
Content of a clinical1
  • to develop and validate the content of a clinical protocol aimed at prevention of cervical cancer in primary care. (scielo.br)
Diagnosis5
  • Volume 1 primarily focuses on revised clinical protocols and provides information on new research to help guide decisions and criteria regarding diagnosis, management, and treatment of hearing-related issues. (routledge.com)
  • 3 American Osteopathic Association (AOA) protocols for the use of OMT state that the "diagnosis must be specific. (jaoa.org)
  • 2) To determine clinical and simple laboratory indicators for diagnosis of patients with vaginal discharge in the local setting. (bmj.com)
  • Objectives To validate the efficiency of the application of a diagnostic protocol based on the patterns of presentation of uveitis to establish the diagnosis. (bmj.com)
  • Inclusion criteria are a clinical diagnosis of hemorrhagic or ischemic stroke and the possibility to start treatment within 12 hours from onset of symptoms. (pubmedcentralcanada.ca)
Colorectal Cancer1
  • An exploratory study of the follow-up care needs of patients treated for colorectal cancer," Journal of Clinical Nursing , vol. 19, pp. 3291-3300, 2010. (hindawi.com)
Laboratory3
  • An expert working group of the International Osteoporosis Foundation (IOF) and the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) has released a new position paper which reviews the evidence of bone turnover markers (BTMs) in fracture risk prediction and monitoring of osteoporosis therapy. (redorbit.com)
  • OBJECTIVES: (1) To compare the effectiveness of two clinical protocols for the management of vaginal discharge in the situations where no laboratory facilities are available but speculum examination is possible and where basic laboratory facilities are available. (bmj.com)
  • Simple clinical indicators for candidiasis, bacterial vaginosis, or trichomonas as in protocol A are sufficiently sensitive and specific for use in situations with no laboratory support. (bmj.com)
Results6
  • The purpose of this study is to detect increasing medication dose results in heroin cessation for patients still using, to determine if decreasing medication dose in patients unable to tolerate medication dose increases retention, and to determine if blood levels of methadone or buprenorphine correlate with clinical response. (clinicaltrials.gov)
  • Now a second clinical study will assess whether this reduced exposure is maintained over the longer term, and also whether longer term exposure reduction results in detectable changes in biological effect. (bio-medicine.org)
  • Total disc replacement has emerged as a viable treatment but the complexity of the spine is reflected in the clinical results, which trail far behind the success of hip and knee arthroplasty. (bl.uk)
  • Results Time to return was significantly shorter for the players in the L-protocol, mean 28 days (1SD±15, range 8-58 days), compared with the C-protocol, mean 51 days (1SD±21, range 12-94 days). (bmj.com)
  • The results of the study show a discrepancy between the absorbed dose-to-water determined according to TG-21 and TG-51 protocols of about 1.4% and 1.7% for 6 and 18 MV photon beams, respectively. (oregonstate.edu)
  • We divided the results into four categories, patient barriers, provider barriers, protocol barriers and health system barriers. (aacrjournals.org)
Populations1
  • TriNetX offers robust query and analytics tools that enable real-time analyses of patient populations which are helping our customers design better protocols, select the right sites and recruit patients faster. (thestreet.com)
Effectiveness1
  • In this meta-analysis we assessed safety and clinical effectiveness of procalcitonin-based protocols to initiate or discontinue antibiotics in patients presenting with AECOPD. (bmj.com)
Mechanical ventilation3
  • Nurse-driven, protocol-directed weaning from mechanical ventilation improves clinical outcomes and is well accepted by intensive care unit physicians. (freecme.com)
  • The purpose of this study was to compare the usual method of physician-directed weaning from mechanical ventilation to a weaning protocol directed and managed by bedside ICU nurses. (freecme.com)
  • Main outcomes for comparison included duration of mechanical ventilation (days), ICU length of stay, ventilator-associated pneumonia (VAP) rates, hospital mortality, and physician attitudes toward the nurse-managed protocol. (freecme.com)
Efficacy1
  • A study demonstrating the efficacy of their protocol is being presented at the American College of Surgeons Clinical Congress in Boston, Massachusetts on October 24. (eurekalert.org)
Facilitators1
  • The survey queried respondents about their opinions on the current impediments to and facilitators of cancer clinical trial accrual at the University of Chicago as well as asking for their opinions on ways to improve the process. (aacrjournals.org)
Rehabilitation4
  • The aim of this paper was to present structured rehabilitation protocols in two different patient groups with upper extremity nerve injuries using sEMG biofeedback. (frontiersin.org)
  • The rehabilitation protocol for group 1 included guided sEMG training to facilitate initial movements, to increase awareness of the new target muscle, and later, to facilitate separation of muscular activities. (frontiersin.org)
  • Study design Prospective randomised comparison of two rehabilitation protocols. (bmj.com)
  • The primary objective of all rehabilitation protocols is to return the player as soon as possible to the prior level of performance with a minimal risk of injury recurrence. (bmj.com)
Findings3
  • When treatment in a clinical technique study is not based on the findings of a patient's medical history and physical examination, how can we be practicing osteopathic medicine or be studying the effects of a truly osteopathic manipulative procedure? (jaoa.org)
  • Without complete reporting of the outcomes studied, evidence-based clinical and policy decisions are limited and researchers cannot synthesise, replicate or build on existing research findings. (bmj.com)
  • DISCUSSION: These findings suggest sensorimotor control disturbances in individuals with chronic idiopathic neck pain may not be present, spawning debate on the clinical usefulness of these tests. (medworm.com)
25,0001
  • We bring together approximately 25,000 clinical and commercial minds with the ability to support customers in more than 110 countries. (benzinga.com)
Phase2
  • Revisions were also made to the protocol for EMBARK, a randomized Phase 3 study of enzalutamide plus leuprolide, enzalutamide monotherapy, and leuprolide alone in men with high-risk non-metastatic HSPC. (prnewswire.com)
  • The proposed Phase 3 clinical trial is designed as an adequate and well controlled, double-blind, adaptive design, placebo-controlled multinational study of CSP-1103 administered to subjects with MCI due to AD who have biomarker evidence supporting this condition. (cnbc.com)
Subjects2
  • Your human subjects study may meet the NIH definition of a clinical trial. (nih.gov)
  • The plate counts generated are then used to determine which treatments are the most effective at reducing the number of microorganisms associated with diseases on the skin of clinical trial subjects. (selectscience.net)
Facilitate1
  • By providing guidance for key content, the SPIRIT recommendations aim to facilitate the drafting of high-quality protocols. (nih.gov)
Viral2
  • In this study, we quantifiably and extensively compared classical and modern experimental approaches for virus purification and enrichment to finalize a protocol for unbiased detection of emerging viruses directly from organ tissues (tissue-based unbiased virus detection for viral metagenomics [TUViD-VM]) for an increased signal-to-noise ratio (ratio of virus genome to host genome) in virus detection. (cdc.gov)
  • Schematic description of tissue-based universal virus detection for viral metagenomics protocol. (cdc.gov)
Regulatory1
  • RESEARCH TRIANGLE PARK, NC --(Marketwired - December 18, 2014) - Today's strict regulatory environment necessitates that pharmaceutical companies adhere to clinical investigator fair market value (FMV) for trial-related compensation. (marketwired.com)
Organization3
  • Join the world's largest organization that represents clinical endocrinologists, with over 6,500 members in the United States and 97 other countries. (aace.com)
  • A common protocol structure and organization facilitates protocol review by oversight entities. (nih.gov)
  • Never developed in isolation, all our protocols are fully verified through the operational components of the organization. (worldwide.com)
Clinical outcomes and mortality before and after implementation of a pediatric sepsis protocol in a limited resource setting: A...
Clinical outcomes and mortality before and after implementation of a pediatric sepsis protocol in a limited resource setting: A... (journals.plos.org)
Cannabics Pharmaceuticals Submits Protocol For An Ex Vivo Clinical Study On Biopsies And Cannabinoids - Barchart.com
Cannabics Pharmaceuticals Submits Protocol For An Ex Vivo Clinical Study On Biopsies And Cannabinoids - Barchart.com (barchart.com)
Identification and quantification of plasma free salusin-β, an endogenous parasympathomimetic peptide | Scientific Reports
Identification and quantification of plasma free salusin-β, an endogenous parasympathomimetic peptide | Scientific Reports (nature.com)
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated...
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated... (pnas.org)
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma...
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma... (pnas.org)
Pre-Clinical Models - Techniques and Protocols | Paul C. Guest | Springer
Pre-Clinical Models - Techniques and Protocols | Paul C. Guest | Springer (springer.com)
Molecular Bacteriology | SpringerLink
Molecular Bacteriology | SpringerLink (link.springer.com)
Home - Professor Kath Maitland
Home - Professor Kath Maitland (imperial.ac.uk)
Michail Lionakis, M.D., Sc.D. | NIH: National Institute of Allergy and Infectious Diseases
Michail Lionakis, M.D., Sc.D. | NIH: National Institute of Allergy and Infectious Diseases (niaid.nih.gov)
ISCEV standard for clinical pattern electroretinography (PERG): 2012 update | SpringerLink
ISCEV standard for clinical pattern electroretinography (PERG): 2012 update | SpringerLink (link.springer.com)
Gene transfer in humans using a conditionally replicating lentiviral vector | PNAS
Gene transfer in humans using a conditionally replicating lentiviral vector | PNAS (pnas.org)
Gene Therapy of Cancer | SpringerLink
Gene Therapy of Cancer | SpringerLink (link.springer.com)
About Clinical Trials | National Heart, Lung, and Blood Institute (NHLBI)
About Clinical Trials | National Heart, Lung, and Blood Institute (NHLBI) (nhlbi.nih.gov)
Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized...
Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized... (nature.com)
Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear...
Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear... (jimmunol.org)
Benefits and harms in clinical trials of duloxetine for treatment of major depressive disorder: comparison of clinical study...
Benefits and harms in clinical trials of duloxetine for treatment of major depressive disorder: comparison of clinical study... (bmj.com)
Plus it
Plus it (care.diabetesjournals.org)
Subjects
Subjects (apps.who.int)
Tips for keeping your practice in business during the COVID-19 pandemic | American Medical Association
Tips for keeping your practice in business during the COVID-19 pandemic | American Medical Association (ama-assn.org)
Evidence-Based Clinical Chelation: A Textbook with Protocols for the ... - Dr. Eleonore Blaurock-Busch, PhD, Dr. Swaran J.S....
Evidence-Based Clinical Chelation: A Textbook with Protocols for the ... - Dr. Eleonore Blaurock-Busch, PhD, Dr. Swaran J.S.... (books.google.com)
Frontiers | Familial Longevity Is Not Associated with Major Differences in the Hypothalamic-Pituitary-Gonadal Axis in Healthy...
Frontiers | Familial Longevity Is Not Associated with Major Differences in the Hypothalamic-Pituitary-Gonadal Axis in Healthy... (frontiersin.org)
Analysis of the Cellular Mechanism of Antitumor Responses and Autoimmunity in Patients Treated with CTLA-4 Blockade | The...
Analysis of the Cellular Mechanism of Antitumor Responses and Autoimmunity in Patients Treated with CTLA-4 Blockade | The... (jimmunol.org)
Retinal Gene Therapy | SpringerLink
Retinal Gene Therapy | SpringerLink (link.springer.com)
Advances in Audiology and Hearing Science: Volume 1: Clinical Protocols and Hearing Devices, 1st Edition (Hardback) - Routledge
Advances in Audiology and Hearing Science: Volume 1: Clinical Protocols and Hearing Devices, 1st Edition (Hardback) - Routledge (routledge.com)
Cognizant Technology Solutions (CTSH) Stock Price, Quote, History & News
Cognizant Technology Solutions (CTSH) Stock Price, Quote, History & News (finance.yahoo.com)
From an Uncertain to a Triumphant Future: Caroline's Story | Memorial Sloan Kettering Cancer Center
From an Uncertain to a Triumphant Future: Caroline's Story | Memorial Sloan Kettering Cancer Center (mskcc.org)
Obesity : Wikis (The Full Wiki)
Obesity : Wikis (The Full Wiki) (thefullwiki.org)
Plasma Exosome Profiling of Cancer Patients by a Next Generation Systems Biology Approach | Scientific Reports
Plasma Exosome Profiling of Cancer Patients by a Next Generation Systems Biology Approach | Scientific Reports (nature.com)
Vaccine experts speak out on COVID-19 vaccines and how to prepare | by Ariadne Labs | Oct, 2020 | Medium
Vaccine experts speak out on COVID-19 vaccines and how to prepare | by Ariadne Labs | Oct, 2020 | Medium (medium.com)
Study of Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer | Rush System
Study of Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer | Rush System (rush.edu)
Treatment Study for Patients With Desmoplastic Melanoma | Rush System
Treatment Study for Patients With Desmoplastic Melanoma | Rush System (rush.edu)
Frontiers | Mobile App-Based Intervention for Adolescents With First-Episode Psychosis: Study Protocol for a Pilot Randomized...
Frontiers | Mobile App-Based Intervention for Adolescents With First-Episode Psychosis: Study Protocol for a Pilot Randomized... (frontiersin.org)
January 2019 - Volume 98 - Issue 1 : Medicine
January 2019 - Volume 98 - Issue 1 : Medicine (journals.lww.com)