Clinical Laboratory Techniques: Techniques used to carry out clinical investigative procedures in the diagnosis and therapy of disease.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Laboratories: Facilities equipped to carry out investigative procedures.Laboratories, Hospital: Hospital facilities equipped to carry out investigative procedures.Chemistry, Clinical: The specialty of ANALYTIC CHEMISTRY applied to assays of physiologically important substances found in blood, urine, tissues, and other biological fluids for the purpose of aiding the physician in making a diagnosis or following therapy.Clinical Laboratory Information Systems: Information systems, usually computer-assisted, designed to store, manipulate, and retrieve information for planning, organizing, directing, and controlling administrative and clinical activities associated with the provision and utilization of clinical laboratory services.Quality Control: A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)Laboratory Infection: Accidentally acquired infection in laboratory workers.Medical Laboratory Personnel: Health care professionals, technicians, and assistants staffing LABORATORIES in research or health care facilities.Medical Laboratory Science: The specialty related to the performance of techniques in clinical pathology such as those in hematology, microbiology, and other general clinical laboratory applications.Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).Evaluation Studies as Topic: Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.Pathology, Clinical: A subspecialty of pathology applied to the solution of clinical problems, especially the use of laboratory methods in clinical diagnosis. (Dorland, 28th ed.)Laboratory Proficiency Testing: Assessments aimed at determining agreement in diagnostic test results among laboratories. Identical survey samples are distributed to participating laboratories, with results stratified according to testing methodologies.Clinical Chemistry Tests: Laboratory tests demonstrating the presence of physiologically significant substances in the blood, urine, tissue, and body fluids with application to the diagnosis or therapy of disease.Bacteriological Techniques: Techniques used in studying bacteria.Reagent Kits, Diagnostic: Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.Reference Standards: A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.Candida: A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; vulvovaginal candidiasis (CANDIDIASIS, VULVOVAGINAL), and thrush (see CANDIDIASIS, ORAL). (From Dorland, 28th ed)Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Animals, LaboratoryAntifungal Agents: Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.Autoanalysis: Method of analyzing chemicals using automation.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Physicians' Offices: The room or rooms in which the physician and staff provide patient care. The offices include all rooms in the physician's office suite.Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Blood Chemical Analysis: An examination of chemicals in the blood.Hematology: A subspecialty of internal medicine concerned with morphology, physiology, and pathology of the blood and blood-forming tissues.Microbiology: The study of microorganisms such as fungi, bacteria, algae, archaea, and viruses.Itraconazole: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Specimen Handling: Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Microbiological Techniques: Techniques used in microbiology.Drug Resistance, Microbial: The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Enterobacteriaceae: A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.Agar: A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.Laboratory Personnel: Professionals, technicians, and assistants staffing LABORATORIES.Clinical Laboratory Services: Organized services provided by MEDICAL LABORATORY PERSONNEL for the purpose of carrying out CLINICAL LABORATORY TECHNIQUES used for the diagnosis, treatment, and prevention of disease.Molecular Diagnostic Techniques: MOLECULAR BIOLOGY techniques used in the diagnosis of disease.Colorimetry: Any technique by which an unknown color is evaluated in terms of standard colors. The technique may be visual, photoelectric, or indirect by means of spectrophotometry. It is used in chemistry and physics. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Immunoassay: A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.Mycology: The study of the structure, growth, function, genetics, and reproduction of fungi, and MYCOSES.Bacteria, AnaerobicAutomation: Controlled operation of an apparatus, process, or system by mechanical or electronic devices that take the place of human organs of observation, effort, and decision. (From Webster's Collegiate Dictionary, 1993)Facility Regulation and Control: Formal voluntary or governmental procedures and standards required of hospitals and health or other facilities to improve operating efficiency, and for the protection of the consumer.Bacteriology: The study of the structure, growth, function, genetics, and reproduction of bacteria, and BACTERIAL INFECTIONS.Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.Diagnostic Errors: Incorrect diagnoses after clinical examination or technical diagnostic procedures.Oxacillin: An antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Medicare Part B: The voluntary portion of Medicare, known as the Supplementary Medical Insurance (SMI) Program, that includes physician's services, home health care, medical services, outpatient hospital services, and laboratory, pathology, and radiology services. All persons entitled to Medicare Part A may enroll in Medicare Part B on a monthly premium basis.ComputersFlucytosine: A fluorinated cytosine analog that is used as an antifungal agent.Blood Specimen Collection: The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.False Positive Reactions: Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)Fungi: A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.Hematologic Tests: Tests used in the analysis of the hemic system.TriazolesCandidiasis: Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)Staphylococcus: A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.Bacterial Typing Techniques: Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.Licensure: The legal authority or formal permission from authorities to carry on certain activities which by law or regulation require such permission. It may be applied to licensure of institutions as well as individuals.Reference Values: The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.Maintenance: The upkeep of property or equipment.United StatesBiological Warfare: Warfare involving the use of living organisms or their products as disease etiologic agents against people, animals, or plants.Quality Assurance, Health Care: Activities and programs intended to assure or improve the quality of care in either a defined medical setting or a program. The concept includes the assessment or evaluation of the quality of care; identification of problems or shortcomings in the delivery of care; designing activities to overcome these deficiencies; and follow-up monitoring to ensure effectiveness of corrective steps.Gram-Negative Bacteria: Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.Methods: A series of steps taken in order to conduct research.Cefmetazole: A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.Diagnostic Tests, Routine: Diagnostic procedures, such as laboratory tests and x-rays, routinely performed on all individuals or specified categories of individuals in a specified situation, e.g., patients being admitted to the hospital. These include routine tests administered to neonates.Pathology Department, Hospital: Hospital department which administers and provides pathology services.Point-of-Care Systems: Laboratory and other services provided to patients at the bedside. These include diagnostic and laboratory testing using automated information entry.Enterococcus: A genus of gram-positive, coccoid bacteria consisting of organisms causing variable hemolysis that are normal flora of the intestinal tract. Previously thought to be a member of the genus STREPTOCOCCUS, it is now recognized as a separate genus.Blood: The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.beta-Lactamases: Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.Competitive Bidding: Pricing statements presented by more than one party for the purpose of securing a contract.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Automation, Laboratory: Controlled operations of analytic or diagnostic processes, or systems by mechanical or electronic devices.Credentialing: The recognition of professional or technical competence through registration, certification, licensure, admission to association membership, the award of a diploma or degree, etc.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Mycobacterium: A genus of gram-positive, aerobic bacteria. Most species are free-living in soil and water, but the major habitat for some is the diseased tissue of warm-blooded hosts.MycosesHaemophilus: A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.Calibration: Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.Feces: Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.Centers for Disease Control and Prevention (U.S.): An agency of the UNITED STATES PUBLIC HEALTH SERVICE that conducts and supports programs for the prevention and control of disease and provides consultation and assistance to health departments and other countries.Nephelometry and Turbidimetry: Chemical analysis based on the phenomenon whereby light, passing through a medium with dispersed particles of a different refractive index from that of the medium, is attenuated in intensity by scattering. In turbidimetry, the intensity of light transmitted through the medium, the unscattered light, is measured. In nephelometry, the intensity of the scattered light is measured, usually, but not necessarily, at right angles to the incident light beam.Coagulase: Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.Centrifugation: Process of using a rotating machine to generate centrifugal force to separate substances of different densities, remove moisture, or simulate gravitational effects. It employs a large motor-driven apparatus with a long arm, at the end of which human and animal subjects, biological specimens, or equipment can be revolved and rotated at various speeds to study gravitational effects. (From Websters, 10th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Enterobacteriaceae Infections: Infections with bacteria of the family ENTEROBACTERIACEAE.Bacterial Infections: Infections by bacteria, general or unspecified.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Mycological Typing Techniques: Procedures for identifying types and strains of fungi.Candida albicans: A unicellular budding fungus which is the principal pathogenic species causing CANDIDIASIS (moniliasis).Yeasts: A general term for single-celled rounded fungi that reproduce by budding. Brewers' and bakers' yeasts are SACCHAROMYCES CEREVISIAE; therapeutic dried yeast is YEAST, DRIED.Legislation, Medical: Laws and regulations, pertaining to the field of medicine, proposed for enactment or enacted by a legislative body.Cryptococcus: A mitosporic Tremellales fungal genus whose species usually have a capsule and do not form pseudomycellium. Teleomorphs include Filobasidiella and Fidobasidium.Guidelines as Topic: A systematic statement of policy rules or principles. Guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by convening expert panels. The text may be cursive or in outline form but is generally a comprehensive guide to problems and approaches in any field of activity. For guidelines in the field of health care and clinical medicine, PRACTICE GUIDELINES AS TOPIC is available.Parasitology: The study of parasites and PARASITIC DISEASES.Cryptococcus neoformans: A species of the fungus CRYPTOCOCCUS. Its teleomorph is Filobasidiella neoformans.Disk Diffusion Antimicrobial Tests: A method where a culturing surface inoculated with microbe is exposed to small disks containing known amounts of a chemical agent resulting in a zone of inhibition (usually in millimeters) of growth of the microbe corresponding to the susceptibility of the strain to the agent.Laboratory Animal Science: The science and technology dealing with the procurement, breeding, care, health, and selection of animals used in biomedical research and testing.Drug Resistance, Bacterial: The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Gram-Positive Cocci: Coccus-shaped bacteria that retain the crystal violet stain when treated by Gram's method.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.United States Public Health Service: A constituent organization of the DEPARTMENT OF HEALTH AND HUMAN SERVICES concerned with protecting and improving the health of the nation.Candidiasis, Oral: Infection of the mucous membranes of the mouth by a fungus of the genus CANDIDA. (Dorland, 27th ed)Clinical Medicine: The study and practice of medicine by direct examination of the patient.Staphylococcus aureus: Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.Gram-Negative Bacterial Infections: Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.False Negative Reactions: Negative test results in subjects who possess the attribute for which the test is conducted. The labeling of diseased persons as healthy when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)Gram-Positive Bacterial Infections: Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.Acinetobacter: A genus of gram-negative bacteria of the family MORAXELLACEAE, found in soil and water and of uncertain pathogenicity.Accreditation: Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.Ceftizoxime: A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.Ketoconazole: Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.Indicators and Reagents: Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)Virology: The study of the structure, growth, function, genetics, and reproduction of viruses, and VIRUS DISEASES.Decision Support Systems, Management: Computer-based systems that enable management to interrogate the computer on an ad hoc basis for various kinds of information in the organization, which predict the effect of potential decisions.Penicillins: A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)

Laboratory assay reproducibility of serum estrogens in umbilical cord blood samples. (1/1942)

We evaluated the reproducibility of laboratory assays for umbilical cord blood estrogen levels and its implications on sample size estimation. Specifically, we examined correlation between duplicate measurements of the same blood samples and estimated the relative contribution of variability due to study subject and assay batch to the overall variation in measured hormone levels. Cord blood was collected from a total of 25 female babies (15 Caucasian and 10 Chinese-American) from full-term deliveries at two study sites between March and December 1997. Two serum aliquots per blood sample were assayed, either at the same time or 4 months apart, for estrone, total estradiol, weakly bound estradiol, and sex hormone-binding globulin (SHBG). Correlation coefficients (Pearson's r) between duplicate measurements were calculated. We also estimated the components of variance for each hormone or protein associated with variation among subjects and variation between assay batches. Pearson's correlation coefficients were >0.90 for all of the compounds except for total estradiol when all of the subjects were included. The intraclass correlation coefficient, defined as a proportion of the total variance due to between-subject variation, for estrone, total estradiol, weakly bound estradiol, and SHBG were 92, 80, 85, and 97%, respectively. The magnitude of measurement error found in this study would increase the sample size required for detecting a difference between two populations for total estradiol and SHBG by 25 and 3%, respectively.  (+info)

Comparison of European and North American malignant hyperthermia diagnostic protocol outcomes for use in genetic studies. (2/1942)

BACKGROUND: Halothane and caffeine diagnostic protocols and an experimental ryanodine test from the North American Malignant Hyperthermia (MH) Group (NAMHG) and the European MH Group (EMHG) have not been compared in the same persons until now. METHODS: The outcomes of the NAMHG and EMHG halothane and caffeine contracture tests were compared in 84 persons referred for diagnostic testing. In addition, the authors assessed the experimental ryanodine protocol in 50 of these persons. RESULTS: Although the NAMHG and EMHG halothane protocols are slightly different methodologically, each yielded outcomes in close (84-100%) agreement with diagnoses made by the other protocol. Excluding 23 persons judged to be equivocal (marginally positive responders) by the EMHG protocol resulted in fewer persons classified as normal and MH susceptible (42 and 19, respectively) than those classified by the NAMHG protocol (48 and 34, respectively). For the 61 persons not excluded as equivocal, the diagnoses were identical by both protocols, with the exception of one person who was diagnosed as MH susceptible by the NAMHG protocol and as "normal" by the EMHG protocol. The NAMHG protocol produced only two equivocal diagnoses. Therefore, a normal or MH diagnosis by the NAMHG protocol was frequently associated with an equivocal diagnosis by the EMHG protocol. The time to 0.2-g contracture after the addition of 1 microM ryanodine completely separated populations, which was in agreement with the EMHG protocol and, except for one person, with the NAMHG protocol. CONCLUSIONS: Overall, the NAMHG and EMHG protocols and the experimental ryanodine test yielded similar diagnoses. The EMHG protocol reduced the number of marginal responders in the final analysis, which may make the remaining diagnoses slightly more accurate for use in genetic studies.  (+info)

European interlaboratory comparison of breath 13CO2 analysis. (3/1942)

The BIOMED I programme Stable Isotopes in Gastroenterology and Nutrition (SIGN) has focused upon evaluation and standardisation of stable isotope breath tests using 13C labelled substrates. The programme dealt with comparison of 13C substrates, test meals, test conditions, analysis techniques, and calculation procedures. Analytical techniques applied for 13CO2 analysis were evaluated by taking an inventory of instrumentation, calibration protocols, and analysis procedures. Two ring tests were initiated measuring 13C abundances of carbonate materials. Evaluating the data it was found that seven different models of isotope ratio mass spectrometers (IRMS) were used by the participants applying both the dual inlet system and the continuous flow configuration. Eight different brands of certified 13C reference materials were used with a 13C abundance varying from delta 13CPDB -37.2 to +2.0/1000. CO2 was liberated from certified material by three techniques and different working standards were used varying from -47.4 to +0.4/1000 in their delta 13CPDB value. The standard deviations (SDs) found for all measurements by all participants were 0.25/1000 and 0.50/1000 for two carbonates used in the ring tests. The individual variation for the single participants varied from 0.02 /1000 (dual inlet system) to 0.14/1000 (continuous flow system). The measurement of the difference between two carbonates showed a SD of 0.33/1000 calculated for all participants. Internal precision of IRMS as indicated by the specifications of the different instrument suppliers is < 0.3/1000 for continuous flow systems. In this respect it can be concluded that all participants are working well within the instrument specifications even including sample preparation. Increased overall interlaboratory variation is therefore likely to be due to non-instrumental conditions. It is possible that consistent differences in sample handling leading to isotope fractionation are the causes for interlaboratory variation. Breath analysis does not require sample preparation. As such, interlaboratory variation will be less than observed for the carbonate samples and within the range indicated as internal precision for continuous flow instruments. From this it is concluded that pure analytical interlaboratory variation is acceptable despite the many differences in instrumentation and analytical protocols. Coordinated metabolic studies appear possible, in which different European laboratories perform 13CO2 analysis. Evaluation of compatibility of the analytical systems remains advisable, however.  (+info)

Effects of a computerised protocol management system on ordering of clinical tests. (4/1942)

OBJECTIVE: To assess the effects of a computerised protocol management system on the number, cost, and appropriateness of laboratory investigations requested. DESIGN: A before and after intervention. SETTING: A supraregional liver unit in a teaching hospital. PATIENTS: 1487 consecutive patients admitted during 1990 and 1991 (one year before and one year after introduction of the system). INTERVENTION: Introduction of a computerised protocol management system on 1 January 1991. MAIN MEASURES: The number and cost of clinical chemistry tests requested per patient day. RESULTS: The total number of clinical chemistry tests requested per patient day by the unit declined 17% (p < 0.001, Student's t test) and of out of hours tests requested per patient day from 0.31 to 0.16, 48% (p < 0.001; Mann-Whitney U test), resulting in a 28% reduction (p < 0.001) in direct laboratory expenditure per patient-day. Overall, the number of tests per admission decreased by 24% (p < 0.001; Mann-Whitney U test). CONCLUSION: Use of the computerised protocol management system resulted in closer compliance with the protocols and a significant reduction in the overall level of requesting. IMPLICATIONS: Although similar systems need to be tested in other clinical settings, computerised protocol management systems may be important in providing appropriate and cost effective health care.  (+info)

The diagnosis, classification, and management of asthma according to severity. (5/1942)

This activity is designed for primary care and specialist physicians. GOAL: To provide prompt and appropriate treatment for asthma of all levels of severity resulting in improved level of activity and decreased need for urgent care and hospitalization with a possible reduction in the annual decline of lung function, degree of permanent airway damage, and mortality. OBJECTIVES: 1. To provide a framework on the basis of history, physical findings, and laboratory results for the diagnosis of asthma. 2. To improve the ability to classify asthma by degree of severity. 3. To describe an incremental therapeutic approach to asthma by degree of severity. 4. To provide a systematic approach with regard to periodic reevaluation of asthma severity and modification of the treatment plan.  (+info)

A cost/efficacy analysis of oral antifungals indicated for the treatment of onychomycosis: griseofulvin, itraconazole, and terbinafine. (6/1942)

This analysis was conducted at HIP Health plan of New Jersey (a Northeastern group model health maintenance organization) to determine the most cost-effective therapy among the three currently available oral antifungal drugs that are indicated for the treatment of onychomycosis: griseofulvin, itraconazole, and terbinafine. Costs of an appropriate and complete treatment regimen were calculated for each of the three drugs based on average wholesale price. Efficacy was determined by meta-analysis of the published literature for those studies where appropriate treatment regimens for onychomycosis were put to use. Efficacy outcome measures were limited to mycologic cure rates in the more recalcitrant cases of toenail onychomycosis. From these measures of cost and efficacy, a cost/efficacy ratio was calculated for each drug by dividing the cost per treatment by the weighted average mycological cure rate. This ratio represents the cost per mycologically cured infection. The final outcome measure (the cost per mycologically cured infection) was $2,721.28, $1,845.05, and $648.96, for griseofulvin, itraconazole, and terbinafine continuous therapies, respectively. For itraconazole and terbinafine pulse therapy, the costs were $855.88 and $388.50, respectively. For both continuous and pulse therapy, terbinafine is apparently the most cost-effective drug, followed by itraconazole and then by griseofulvin. Terbinafine has the fewest drug interactions and the highest treatment success rate.  (+info)

Affinity chromatography: a review of clinical applications. (7/1942)

Affinity chromatography is a type of liquid chromatography that makes use of biological-like interactions for the separation and specific analysis of sample components. This review describes the basic principles of affinity chromatography and examines its use in the testing of clinical samples, with an emphasis on HPLC-based methods. Some traditional applications of this approach include the use of boronate, lectin, protein A or protein G, and immunoaffinity supports for the direct quantification of solutes. Newer techniques that use antibody-based columns for on- or off-line sample extraction are examined in detail, as are methods that use affinity chromatography in combination with other analytical methods, such as reversed-phase liquid chromatography, gas chromatography, and capillary electrophoresis. Indirect analyte detection methods are also described in which immunoaffinity chromatography is used to perform flow-based immunoassays. Other applications that are reviewed include affinity-based chiral separations and the use of affinity chromatography for the study of drug or hormone interactions with binding proteins. Some areas of possible future developments are then considered, such as tandem affinity methods and the use of synthetic dyes, immobilized metal ions, molecular imprints, or aptamers as affinity ligands for clinical analytes.  (+info)

Genetic testing and the clinical laboratory improvement amendments of 1988: present and future. (8/1942)

CLIA '88 superseded CLIA '67. CLIA '88 set standards designed to improve quality and expanded federal oversight to virtually all clinical laboratories in the United States. Presumably because genetics testing was then in its infancy, CLIA '88 did not devote a special section to genetics testing. Biochemical and immunochemical tests used to evaluate inborn errors of metabolism and other genetic entities were categorized as analytes in the Clinical Chemistry section, and DNA probes used primarily in infectious disease were included in Microbiology. The legal, social, economic, and ethical implications of genetic testing and the rapid commercialization of these tests led to recommendations that genetic testing be defined as a laboratory specialty with a subsection in CLIA. The advisory committee created under CLIA was assigned to review these recommendations. The committee agreed that genetics testing was sufficiently different from other areas already included in CLIA to warrant a separate section. Two definitions were adopted. The more clear-cut one is for molecular genetic and cytogenic tests. This includes the analysis of human DNA/RNA in evaluating genetic diseases. The second definition is not as clear-cut and is for the analysis of proteins and metabolites used predominantly to detect inborn errors of metabolism. Many of these analytes already are categorized according to their uses for other purposes. The recommendations for genetic testing include detailed and specific proposals concerning personnel, confidentiality and informed consent, quality control, contamination, proficiency testing, validation of tests, special reporting, retention of records, and reuse of tested specimens.  (+info)

Laboratory analyses, essential in screening, diagnosis, treatment, and monitoring of disease, are indispensable in health care, but appropriate utilization is intricate. The overall aim of this thesis was to study the use of laboratory tests in Sweden with the objective to evaluate and optimize test utilization.. Considerable inter-county variations in test utilization in primary health care in Sweden were found; variations likely influenced by local traditions and habits of test ordering leading to over- as well as underutilization. Optimized test utilization was demonstrated to convey improved quality and substantial cost savings.. It was further established that continuing medical education is a suitable means of optimizing test utilization, and consequently enhancing quality and cost-efficiency, as such education was demonstrated to achieve long-lasting improvements in the test ordering habits of primary health care physicians.. Laboratory tests are closely associated with other, greater, ...
Clinical Laboratory Tests Performed at Geisinger Medical Laboratories includes drugs of abuse, (DAU) therapeutic drug monitoring (TDM), microbiology testing, serologic testing. We provide medical laboratory testing to industry, law enforcement, community hospitals, and physician offices in northeastern and central Pennsylvania.
The OECD Principles of Good Laboratory Practice (GLP) ensure the generation of high quality and reliable test data related to the safety of industrial chemical substances and preparations. The principles have been created in the context of harmonising testing procedures for the Mutual Acceptance of Data (MAD).
Eventbrite - ComplianceOnline presents Method Validation under Good Laboratory Practices (GLP) - Friday, January 5, 2018 - Find event and ticket information.
Cleveland, Ohio. Diagnoses of specific nongynecologic cytology samples may be enhanced with knowledge of certain laboratory test results. These include both exfoliative samples (cerebrospinal fluid, pericardial, peritoneal and pleural fluids) as well as fine needle aspirate cytology samples from body sites such as the thyroid, "neck," lymph nodes and metastatic sites. Following an overview of the subject, a case-based approach is used to highlight laboratory tests that aid in rendering more specific cytologic diagnoses. The use of immunocytochemical stains on cytologic samples to help make more specific diagnoses are also covered.. ...
BackgroundAdjusting for laboratory test results may result in better confounding control when added to administrative claims data in the study of treatment effects.
An AE is any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a medicinal product. An SAE is any untoward medical occurrence that, at any dose, results in death, is life threatening, requires hospitalization or prolongation of existing hospitalization, results in disability/incapacity, is a congenital anomaly/birth defect, or is an event of possible drug-induced liver injury. Refer to the general Adverse AE/SAE module for a complete list of AEs/SAEs. Any abnormal laboratory test result (hematology, clinical chemistry, or urinalysis) or other safety assessments (e.g., electrocardiograms [ECGs], radiological scans, vital sign measurements), including those that worsen from Baseline, and were felt to be clinically significant in the medical and scientific judgment of the investigator, were recorded as AEs or SAEs. Clinically suspected cases of hypersensitivity to ABC were also SAEs ...
The American Society for Microbiology (ASM) is the oldest and largest single life science membership organization in the world. Membership has grown from 59 scientists in 1899 to more than 39,000 members today, with more than one third located outside the United States. The members represent 26 disciplines of microbiological specialization plus a division for microbiology educators.
The American Society for Microbiology (ASM) is the oldest and largest single life science membership organization in the world. Membership has grown from 59 scientists in 1899 to more than 39,000 members today, with more than one third located outside the United States. The members represent 26 disciplines of microbiological specialization plus a division for microbiology educators.
Creatinine Blood Test in lab Kidney Function Panel Colorimetric Technique (Jaffes Method) General Concept 1) Names:- Formal name: Creatinine Also known as: Creat; Blood Creatinine; Serum Creatinine. 2) What is the Creatinine? Read about it in creatinine test,definition and patient eduction. Click here.... Continue reading → ...
If a laboratory test result is outside normal range, you may be encouraged to see a physician. Many tests, to be validated, will need to be repeated at the discretion of a physician. Laboratory test results may vary depending upon age, sex, time of day blood sample is taken, diet, medications, and the limits of modern technology. A single laboratory test or group of tests cannot guarantee good health. False positive and false negative test results are possible. There are various medical diseases that cannot be uncovered by these tests alone. Testing by a medical staff only constitutes a partial evaluation of your state of health and does not represent a diagnosis or treatment of disease ...
Demographics CMS surveyed 4,214 CW sites during April 15, 2002--November 12, 2004. This included 897 sites in 2002, 1,575 sites in 2003, and 1,742 sites in 2004. Of the CW facility types surveyed, POLs compose the largest percentage (47%), followed by skilled nursing facilities (14%) (Table 2). The CW sites surveyed estimated performing a broad range of annual test volumes (Figure 2). Of the facilities surveyed by CMS during 2003--2004 (2002 data not available), 90% reported that they performed no more than five different waived tests, and 99% performed no more than 10 different waived tests. Although the exact volume of each test performed per site is not known, on the basis of the number of sites testing for each analyte, the five most commonly performed waived tests were identified as glucose, dipstick urinalysis, fecal occult blood, urine human chorionic gonadotropin (hCG) (visual color comparison), and group A streptococcal antigen (direct test from throat swabs) (Figure 3). This correlates ...
Unnecessary or inappropriate laboratory testing significantly contributes to rising health care costs. This session will include strategies for identifying and reducing unnecessary testing. The role of laboratory leadership in maximizing efficient use will be discussed. The complexity surrounding utilization of genetic tests will also be addressed.. ...
Payers are increasingly demanding value for money. Inappropriate testing has been a concern because it incurs both direct and indirect downstream costs. This symposium will cover the kind of evidence required, gaps in the evidence, and practical approaches for evaluation of laboratory utilization.
OUTLINE: Archived bone marrow and blood samples, distributed to the Eastern Cooperative Oncology Group, Southwest Oncology Group, and Cancer and Leukemia Group B laboratories, are analyzed for leukemia-associated immunophenotype (LAIP) assays and minimal residual disease studies by flow cytometry. Results are then provided to the National Cancer Institute for assessment and comparability of test results. ...
Vartest has developed an updated Test Request form specifically devoted to Anti Microbial finish testing. The form makes it easier and less confusing to submit samples for anti-microbial testing. It serves to confirm which options of the test methods are being requested by the client and also lets the client know in advance of the detail that will appear on their report when Vartest completes it. The Biological Test Request Submit Form can be downloaded at: http://vartest.com/resources/test-request-forms/. The form currently includes submit information for AATCC 30, AATCC 100, AATCC 147, ASTM G21, ASTM E1428, but Vartest also performs many other antimicrobial tests, including ASTM E2149 and MIL STD 810F Method 508.5 Fungus. All of these tests are run with one or more of:. ...
The TSI blood test is typically used to aid in the diagnosis of autoimmune disorders which affect the thyroid. Ordering the TSI Blood Test from Request A Test is an easy and convenient way to get a thyroid test. Call or go online to order your testing today at one of our 1,400 nationwide locations.
The lead profile test can be useful for testing ocupational exposure to lead. Request A Tests convenient, affordable lab testing makes it easy to take charge of your own health.
Michigan Physicians Group is a multi specialty healthcare clinics in Detroit, affiliated with William Beaumont Hospital, Botsford and DMC.
Your Family Doctor can complete the online form for you. Alternatively, you can download the PDF form and bring it to your Family Doctor to complete and send in to us.. ...
Laboratory Diagnostic Testing for Health Conditions. Call Forrest Health at (408)354-4262 for information about natural health products and health tests.
This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturers instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements ...
Lee T. Zane, M.D., M.A.S., University of California, San Francisco, and colleagues assessed the frequency of abnormal laboratory tests in a population of 13,772 patients (aged 13 to 50 years, 51 percent male and 49 percent female) with acne who underwent isoretinoin therapy between 1995 and 2002. The researchers analyzed medical records for each patient before, during and after they took the medication, using information from laboratory tests of triglycerides; total cholesterol; liver transaminase (enzymes) levels; white blood cell (cells that fight infection) count; hemoglobin (which carries oxygen through the body) level; and platelet (involved in blood clotting) count.. Patients taking isoretinoins had an increased incidence of elevated triglyceride, total cholesterol and liver enzyme levels, but not hemoglobin levels, white blood cell counts or platelet counts. Among patients with normal pretreatment laboratory tests, 44 percent developed high triglycerides, 31 percent high cholesterol and ...
Supplies: Stool container, Small (Random), 4 oz Random (T288). Submission Container/Tube: Stool container (T288). Specimen Volume: 5 g. Collection Instructions:. 1. Collect a fresh random stool specimen, no preservatives.. 2. Specimens may be stored refrigerate for up to 72 hours following collection. Specimens must be frozen within 72 hours of collection and remain frozen throughout the shipping process.. 3. Separate specimens must be submitted when multiple tests are ordered. Specimen must be split prior to freezing for transport. Testing cannot be added on to a previously collected specimen. 4. Specimen cannot be collected from a diaper.. ...
Laboratory Values * Languages Português, English Did you saw a laboratory test results and did not know what to think? Relaxe RELAB is an application that comes with the normal values for more than 200 laboratory test...
Hi, my doctor said I can take the endoscopy with duodenal to rule out celiac disease since my TTG IgG was positive. But since my IgA was such a low yield she recommends I get other blood works done before considering taking the endoscopy. Heres a list of my results of the test she wanted me take ...
Verify that the study plan contains the information required for compliance with these Principles of Good Laboratory Practice. This verification should be documented.
SpectrumTM AssureIDTM is a materials checking system which verifies the identity and quality of production materials, confirming suitability for use in the manufacturing process. Unlike free flowing Spectrum software, AssureID ensures standard operating procedures (SOPs) are followed helping to ensure good laboratory practice (GLP).
The Practical Course on Mammalian Protein Expression will offer a comprehensive theoretical introduction and practical training in Transient HEK 293 gene expression (TGE), Baculoviral Insect Cell System (BICS) and mammalian stable cell expression by the RMCE method.. The course is aimed for Post-Doc and PhD level young researchers. The participants have to be working in the field of structural biology or functional and biochemical analysis of proteins relevant for infection research in combination with a structure based approach. Participants with experience in basic cell culture techniques and skilled in good laboratory practice will be selected. Project requests will be selected according to the rules valid for an Instruct cooperation project. Within the course there will be a chance of optional testing of specific constructs for accepted project applications.. The course will cover practical and theoretical aspects of animal cell culture technology for the production of recombinant mammalian ...
Animal models BiostatisticsAdverse Events (AE)BiologyBiomedical SciencesCommunication SkillsData AnalysisDNADNA extractionDNA sequencingFDAGenetic polymorphismGeneticsGenomicsGood Clinical Practice (GCP)Good Laboratory Practice (GLP)ICH guidelinesLaboratory ResearchLaboratory SkillsLaboratory TechniquesLaboratory testingLife SciencesMicrosoft ExcelMicrosoft OfficeMicrosoft PowerpointMicrosoft WordOphthalmologyPCRpharmacologyPhases of clinical development (phase I to IV)Phenotype PowerPointPresentation SkillsqPCRQuantitative PCR (qPCR)real-time PCRResearchRNA isolationScientific WritingSequence AnalysisSequencingSerious Adverse Event (SAE)Teamwork ...
All of the custom DNA and RNA oligonucleotides that IDT offers are synthesized chemically, not enzymatically. As a result, there should not be DNase or RNase present in our samples. It is worth noting that there are abundant nucleases present in most environments, so good laboratory practice is very important to minimize potential exposure ...
The increasing prevalence of obesity has led to an epidemic of diabetes mellitus and related complications, including ASCVD. Prediction of the risk of ASCVD and of developing diabetes in the lab report will simplify and improve the communication of those risks to patients. This panel provides the 10-year and lifetime risk of ASCVD events and the 8-year risk of developing diabetes. The lipid panel results will aid in the assessment of ASCVD. Assessment of 10-year risk of a first atherosclerotic cardiovascular (ASCVD) event is recommended by the 2013 ACC/AHA Guidelines on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults. These guidelines recommend initiating statin therapy based on 10-year ASCVD risk score. Assessment of 8-year risk of developing diabetes mellitus is based on laboratory test results with anthropomorphic data and family history. This algorithm was developed in the Framingham cohort, and is intended to aid in the identification of patients ...
GENERAL INFORMATION. Blood Transfer Device Wall Chart. Maximum Blood Draw Volume Guide. Order of Draw for Multiple Collections. Specimen Collection Quick Guide. Photo Swab Guide. Collection FAQs. Inpatient Labs Frequency Collection Schedule. Zika Guidance for Clinical Labs. Newborn Screen Collection Directions. FORMS. DNA Bank Information and Consent. DNA Bank Information and Consent (Spanish Version). Additional Test Request Form (Add-on Form). Authorization for Autopsy Payment. REQUISITIONS. Allergens Bellevue Exposure Requisition. Biochemical Genetics. Bone Marrow/Malignancy (Off-site collection)- Flow, Morphology, Cytogenetics. Cell Markers. Cytogenetics - Constitutional Studies. General Lab Requisition. Immunology Diagnostics Laboratory (IDL)/Requisition. Miscellaneous Specialty Testing. Molecular Genetics. Pathology Requisition. SCCA Multiple Labs Requisition. LINKS. Seattle Childrens Laboratory. Accreditation/Licensure. Seattle Childrens Hospital. Mayo Medical Laboratories. ...
All the NBRHC test result reports are computer generated. The format is specifically designed to flag any results outside the reference interval.. The NBRHC Laboratory shall report all critical results immediately to the clinical personnel responsible for patient care 24 hours a day, 7 days a week.. Most non-critical routine test results are available in 24 hours; others require more complex testing or may have to be sent to a reference laboratory. These results can take several days to weeks to report.. ...
He or she is a licensed physican who is responsible for receiving and reviewing laboratory results generated by a drug testing program to evaluate laboratory test results to assure proper interpretation of those results. The MRO contacts the employee to advise when the test is postive and provides an opportunity for the employee to present…
I was feeling a bit more tired than usual as the Christmas holidays approached in December 2012, but I chocked it up to the frenetic pace of the season and keeping up with caring for my two young children, ages 4 and 12. I had none of the other typical warning signs of chronic myeloid leukemia (CML): night sweats, fever, and weight loss. I was, however, experiencing severe pain in my side and back, which sent me to the emergency room on Christmas day; it later was determined to be caused by a kidney stone making its way through my urinary tract.. As I waited for the blood and other laboratory test results to come back, a doctor came to tell me that my blood test result showed a white blood cell count of 150,000 cells/mm3 (way beyond the normal range of between 4,000 and 10,000 cells/mm3) and that I had leukemia, although he wasnt sure which type of the cancer I had. Additional diagnostic tests revealed it was CML. My grandmother had died the year before from AML, and I wondered whether I would ...
Siemens Healthineers is committed to becoming the trusted partner of healthcare providers worldwide, enabling them to improve patient outcomes while reducing costs. Driven by our long legacy of engineering excellence and our pioneering approach to developing the latest advancements, we are a global leader in medical imaging, laboratory diagnostics, clinical IT, and services. usa.siemens.com/Healthineers ...
Many kinds of health data are represented as observations. A laboratory test result, a vital sign measurement, a pain scale rating, or recording the kind of exercise activity that a patient engaged in (e.g. running, walking, swimming, etc.) can all be considered observations. In this context, we use observation as a generic term. Depending on the domain of interest, you might call these tests, variables, or data elements, etc.
Tim, we have a new Triple G system, which I am still trying to perfect. It has a good AP unit. To try to answer your questions: Do your pathologists request tests through the LIS? Yes, they order all recuts, restains, specials, immunos, reference testing, etc. We have such a good tracking system that we use this as documented physician order. Notes can be written at specimen, block and specimen level, stains ordered on unstained levels, etc. Its a good way to document the time they ordered it, etc. They cant say they did it before cut off time when they didnt! Do you enter tests performed and results obtained on each slide? Tests are ordered on block and slide but results are not entered except generally in the report. Can you print out reports by case, test-type (special stain, antibody, etc) or other parameters? Yes, I will be able to, but I dont have the Crystal report customized yet. Can you print out a report per case showing all test requests, all tests performed and all results? Yes, ...
Specimens must be analyzed within 72 hours of collection in EDTA or within 48 hours of collection in heparin. Some medications may affect immunophenotyping results and should be listed on the patient test request form ...
Specimens must be analyzed within 72 hours of collection in EDTA or within 48 hours of collection in heparin. Some medications may affect immunophenotyping results and should be listed on the patient test request form ...
Hi mojo,,br,,br,God, my husband feels it!,br,,br,After 7 failed donor IUI attempts last year we had to make the decision of donor IVF or ICSI with dhs sperm. Unfortunately, around the same time a battle with the CSA came to a head - they sent a demand for over £3,000 (to be paid immediately) and flatly refused to take account of a DNA test request following a report from our infertility Dr that the chances of his daughter actually being his was slim to nothing (he has 96% abnormal sperm).,br,,br,My hubs flipped - he became so convinced that Id be better off without him that he went AWOL for over 2 days - of course I flipped then too.,br,,br,Having said all this, he came back, the day he left the CSA agreed to the DNA test (which was eventually +ve - so hes already had one miracle) and after some time of sorting ourselves out, we are stronger now than we have ever been. ,br,,br,When he can, he lurks in the background when Im in the chatroom (sorry if that sounds purvy - its not meant to be:) ...
ការអនុវត្តជាក់ស្តែងរបស់និស្សិតផ្នែកបច្ចេកទេសមន្ទីរពិសោធន៍នៅតាមមន្ទីរពេទ្យ។ View the embedded image gallery online at: http://fhs.puthisastra.ed...
It is important to prepare for your tests as instructed to ensure that your test results are reliable. Follow any instructions you are given as certain behaviors may effect some test results.
According to the company, test results are due out in early March, and there is a huge market opportunity for the drug -- if trial results are successful. According to Charly, after results are announced, the company will either be worth much, much more, or perhaps as much as 70% less -- immediately.. Hey, thats perfect! If the trial results are announced in early March and come in positive, youll be virtually guaranteed a spot near the top of the pile. And if it misses, you wont have to worry about the rest of the contest. Youll be out of the running quickly, with no real money ever lost.. Now, there are only two drawbacks to using Atherogenics -- at a market cap of $480 million, the company is just shy of qualifying for the game at todays price. Also, the trial news could be released just before the contest starts on March 5.. But even if AtheroGenics releases early, there are other companies in the same vein. So if you hope to compete in CNBCs game, thats my advice to you: Find a ...
I need to say something about this test https://www.e-cigarette-forum.com/threa ... g2.807131/ revealed by Mooch in 6/2017. Im not afraid to say that if it wasnt published,the world will be a better place. This is unfortunatelly the example of information which makes more bad than good. There is not a problem in the results themselves. I made tests with similar settings and can confirm that the test results are correct with the Samsung 30Q as a clear winner. The problem is that this particular result leads to generalization that "Samsung 30Q must be then good in other settings as well". I am quite confident that Mooch is another victim of this seductive idea and so he just do not expect that there should be any problem with 30Q cycle life under another, particularly lower test settings. But he cannot be more wrong ...
UPDATE* - The test results are in & Oskar will remain on the kidney medication..and the blood anlysis range was ok (since Osk is administered Metacam regularly for his back...testing his liver function is important). So...all is good & we will continue to retest every 6 months ...
I got a call from the docs office today, and spoke with his nurse. My test results are back, and everything was normal (hormones, thyroid, nutrients, no ...
Science of Laboratory Diagnosis von David Burnett und Buchbewertungen gibt es auf ReadRate.com. Bücher können hier direkt online erworben werden.
WARNING - Many subjects outlined within this site are extremely dangerous and are provided here for information only. Please don`t experiment with high voltages or chemicals unless you are fully conversant with safe laboratory practices. No liability will be accepted for death, injury or damage arising from experimentation using any information or materials supplied. ...
WARNING - Many subjects outlined within this site are extremely dangerous and are provided here for information only. Please don`t experiment with high voltages or chemicals unless you are fully conversant with safe laboratory practices. No liability will be accepted for death, injury or damage arising from experimentation using any information or materials supplied. ...
... - Precision and accuracy of the CardioChek PA and Cholestech LDX analysers were compared to clinical diagnostic laboratory methods. In Find great deals for
UCSD Clinical Investigation Institute and Nature Medicine present Frontiers of Clinical Investigation: Bench to Bedside Aging: From bench to bedside October 18-20, 2007 * La Jolla, California The theme for this years symposium explores innovative approaches to bridge laboratory investigation to clinical research in aging. Dont delay, register today! www.nature.com/natureconferences/cii2007 ...
BACKGROUND: Updated National Academy of Clinical Biochemistry (NACB) Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been developed. METHODS: Published reports relevant to use of tumor markers for 5 cancer sites--testicular, prostate, colorectal, breast, and ovarian--were critically reviewed. RESULTS: For testicular cancer, alpha-fetoprotein, human chorionic gonadotropin, and lactate dehydrogenase are recommended for diagnosis/case finding, staging, prognosis determination, recurrence detection, and therapy monitoring. alpha-Fetoprotein is also recommended for differential diagnosis of nonseminomatous and seminomatous germ cell tumors. Prostate-specific antigen (PSA) is not recommended for prostate cancer screening, but may be used for detecting disease recurrence and monitoring therapy. Free PSA measurement data are useful for distinguishing malignant from benign prostatic disease when total PSA is |10 microg/L. In colorectal cancer, carcinoembryonic antigen is
In April 2012, the Centers for Disease Control and Prevention (CDC) published "Good Laboratory Practice Recommendations for Biochemical Genetic Testing and Newborn Screening for Inherited Metabolic Disorders" as a Morbidity and Mortality Weekly Report (MMWR) Recommendations and Reports publication (1). To assess awareness and use of the recommendations in the MMWR document by the key intended audience - laboratory professionals in biochemical genetic testing (BGT) and public health newborn screening (NBS) laboratories - two facilitated discussion groups were held: one with NBS laboratory professionals and one with BGT laboratory professionals. The groups were held in Atlanta, Georgia, on December 4, 2013, with five and eight participants, respectively. The results presented in this report reflect the feedback from these two discussion groups, summarized into the eight topic areas listed below with clarifying information from the Association of Public Health Laboratories and CDC project team ...
မန္မာစာေရးရင္ ျမန္မာလိုမွန္၊ အဂၤလိပ္ဆိုလဲ သူ႔ဟာနဲ႔သူ မမွားသင့္ပါ။ ကျပားလဲ ရေပမဲ့ အမွန္ေတြ ေရာတာမွ လူရာဝင္ပါတယ္။ အမ်ားဖတ္ဘို႔တင္တာဆိုေတာ့ ဖတ္တဲ့သူေတြကို ေလးစားရပါတယ္။ SMS ေတြလို အတိုေကာက္ေရးတာ၊ အဂၤလိပ္စာကို ျမန္မာ အသံထြက္နဲ႔ ရိုက္တာ၊ ဒီေနရာမွာ မသင့္ေလွ်ာ္ပါ။ တခ်က္လြဲရင္ တသက္လဲ ျဖစ္ႏိုင္လို႔ ကူညီေစခ်င္ပါတယ္ ...
The leading source of information on Texas foundations and nonprofits. Deer disease test results are negative - Sighted In newsletter. A searchable database of more than 80,000 IRS-recognized nonprofit organizations in Texas.
The following outcome measures should be used to assess improvements in laboratory services and in overall TB-control programs. A checklist of key performance indicators is included (Box 3). TB Incidence Improvements in laboratory services should facilitate progress toward elimination of TB and the accomplishment of Healthy People 2010 objective 14-11, which calls for a rate of less than one case per 100,000 persons (31). The laboratory contribution should be evaluated by monitoring 1) the percentage of TB cases for whom microbiology laboratory test results are entered in the Report of a Verified Case of Tuberculosis (RVCT); 2) the percentage of pulmonary or laryngeal TB cases among persons aged ,12 years for whom a sputum culture was done and the data entered in the RVCT; and 3) the percentage of culture-positive TB cases with drug-susceptibility results entered in the RVCT. Treatment Initiation All patients with newly diagnosed, highly infectious TB (i.e., patients with positive acid-fast ...
Clinical Mass Spectrometry Course Series This series of courses is designed for anyone in the clinical laboratory field who wants to learn about mass spectrometry and utilize this technology in the clinical laboratory. Medical laboratory scientists with training in mass spectrometry are in demand in the clinical laboratory.
scil animal care company specializes in laboratory diagnostic equipment for Canadian Veterinarians including hematology analyzers and chemistry analyzers.
NOTOC__ {{SI}} {{CMG}}; {{AE}} ==Overview== Liver function tests (LFTs or LFs), which include liver enzymes, are groups of [[clinical biochemistry]] laboratory blood assays designed to give information about the state of a patients [[liver]]. Most liver diseases cause only mild symptoms initially, but it is vital that these diseases be detected early. Hepatic (liver) involvement in some diseases can be of crucial importance. ==General approach== * Patients with hepatocellular process, have higher elevations in the serum [[aminotransferases]] compared to [[alkaline phosphatase]]. However, patients with cholestatic process have the opposite lab findings. * The elevated serum [[bilirubin]] is a non-specific finding and can be elevated in both hepatocellular and [[cholestatic]] conditions. * The presence of bilirubin in the urine reflects direct [[hyperbilirubinemia]] and hepatobiliary disease. * Unconjugated bilirubin is tightly bound to albumin and is not filtered by the glomerulus. ...
From three data partner sites within the Mini-Sentinel Distributed Database, we identified NSAID initiators aged ≥18 years between 2008 and 2013. Numbers of events and risks within 30 days after NSAID initiation were calculated for four mutually exclusive outcomes: (1) inpatient UGI diagnosis of bleeding or gastric ulcer (standard claims-based definition without laboratory results); (2) non-inpatient UGI diagnosis AND ≥3 g/dl hemoglobin decrease; (3) ≥3 g/dl hemoglobin decrease without UGI diagnosis in any clinical setting; (4) non-inpatient UGI diagnosis, without ≥3 g/dl hemoglobin decrease. ...
In this interview, Dr Navasa from the Hospital Clinic Barcelona discusses how his team is using the Siemens ADVIA Centaur® Enhanced Liver Fibrosis (ELF TM ) Test, in conjunction with advanced imaging techniques for the non-invasive assessment of liver fibrosis. The recent introduction of these advanced tools is enabling physicians to more closely monitor disease progression and adjust treatment strategies accordingly.
In a move designed to give patients more control over their medical records, individuals will be able to obtain copies of their medicals test results directly from the testing lab, according to a rule recently adopted by HHS.
Western has a LifeLabs clinic on campus. LifeLabs is a Canadian company with nearly 50 years of experience serving the needs of Canadians. Laboratory test results are used by healthcare professionals to accurately assess individual patient needs and identify effective treatments ...
I worked as a Biologics Scientist and Pre-Clinical and Clinical Studies Manager, for Critical Pharmaceuticals Ltd, Nottingham. I was a member of a small close-knit team within Critical Pharmaceuticals for over two years. The majority of my time was spent working on the proof of concept of use of the companys proprietary technology for controlled release single dose vaccines. Working towards Good Laboratory Practice (GLP), I ran my own research programme (a BBSRC Small Business Research Initiative), planning and undertaking my own research including devising new assays and collaborating with Unviersity of Nottingham. I also got a good grounding in the running of a small business. I was involved in operations management, preparing reports to our funders (private investors and Research Councils), exploring business development opportunities, marketing and PR, and advising and taking advice from our Directors and advisers. I have also worked in the biochemistry laboratories of an NHS hospital; what ...
Find all books from Kee, Joyce Lafever - Prentice Halls Handbook of Laboratory & Diagnostic Tests: With Nursing Implications. At find-more-books.com you can find used, antique and new books, COMPARE results and immediately PURCHASE your selection at the best price. 9780131180178
The Division of Clinical Biochemistry, Department of Laboratory Medicine & Pathobiology, held its first ever LMP Alumni and Friends Event on August 1, 2017, during the joint AACC-CSCC scientific meeting, a recording-breaking conference of over 21,000 attendees in beautiful San Diego, Califor ...
We have a full line of CBC & other laboratory diagnostic tools to perform sedimentation, heartworm tests & cytological examinations in our DeLand animal clinic.
Nitric oxide and thus restores the natural process leading to an erection. Not all possible interactions are listed in this medication guide? Biceps tendon rupture is one of the most common musculotendinous ruptures? Laboratory test results are not meaningful by themselves. Incerta carri al studies per monteforte, abilify lawsuit update 2019 sebbene assai belga per nodi, sono fare affacciata controvoglia presso aride i dove comprare trial ed set extreme in svizzera del genere, laureatosi per aver gli arredi durante la can del giunta. You owe it to yourself to get this product today? My daughter died suddenly 3 days after her dose of lisinopril was raised from 10 mg to 20 mg! It also failed to disclose a "clinically important" risk of weight loss in children taking Zoloft (sertraline). However, styplon tablet price enterprisingly in this context, it is important to understand that, among these populations, chemotherapy or bone marrow transplantation protocols do not all produce equivalent risk ...
Evidence-based medicine as applied to laboratory medicine for laboratorians, clinicians, and other related health professionals working in the laboratory sciences.
Corresponding to the chapters in Laboratory and Diagnostic Testing in Ambulatory Care, 4th Edition, this workbook provides practice designed to reinforce student understanding of laboratory concepts, terminology, and procedures. Each chapter includes exercises to help students master fundamental concepts, specific procedures, and advanced skills. Competency evaluation sheets designed to meet government standards for good laboratory practice are included for all procedures to track students progress as they become competent with laboratory and diagnostic procedures. With focused coverage on the latest advancements and technologies in the field, this practical workbook gives your students the hands-on practice they need to succeed.
Cincinnati--NetWellness expert Amadeo Pesce, PhD, Department of Pathology and Laboratory Medicine, University of Cincinnati (UC) College of Medicine, has created a new Web series on laboratory testing. This series, one of the first of its kind to be published on the Web, attempts to shed light on the process of laboratory testing by explaining it in a clear and understandable manner and can be found on the internet at netwellness.org.. The results of a lab test can reveal important information such as how a prescribed drug is acting on a patients body and if a patient is receiving too much or too little of a drug. Many people view laboratory testing as a complex and mysterious process. As a result, they often hesitate to undergo testing since they do not know what to expect. "My hope is that by giving people information up front, they will be less anxious when they visit their doctor," said Pesce.. The NetWellness Laboratory Testing Series contains information on topics such as AIDS testing, ...
This is a collection of laboratory methods which in the hands of the writer have shown their relative simplicity and clinical accuracy over a period of years of actual use. Where several methods are known or in common use, the one which practical experience has indicated, for one or another reason to be preferred, has been arbitrarily selected. Some knowledge of laboratory procedure on the part of those using the volume is pre-supposed. No claim is made for originality, and free use has been made of all current text-books. An effort has been made to present concisely such procedures as ...
Enzo Biochem, Inc., a life sciences and biotechnology company, engages in the research, development, manufacture, and marketing of diagnostic and research products based on genetic engineering, biotechnology, and molecular biology. ENZ operates in three segments: Enzo Life Sciences, Enzo Clinical Labs, and Enzo Therapeutics. The Enzo Life Sciences segment manufactures, develops, and markets functional biology and cellular biochemistry products and tools to research and pharmaceutical customers. It offers products applied in the fields of antibiotics, autophagy, cancer, cell cycle, cell death, cell signaling, cell trafficking, genomics/molecular biology, immunology, inflammation, lipid signaling, neurobiology, protein degradation, ROS/RNS, and stress/heat shock. The Enzo Clinical Labs segment offers routine and esoteric clinical laboratory tests or procedures used in general patient care by physicians to establish or support a diagnosis, monitor treatment or medication, and search for an ...
This book is an excellent resource for people who are having a health problem & their doctor does not have a clue. The book empowers you, the patient to work with your doctor and get the care you need. It gives you information on effective medical treatments your health plan doctor might not be aware of. It tells you how to use scientific fundamentals to interpret clinical laboratory tests to find the problem(s) so you can guide your busy doctor to fix it. As an introduction, Dr.Cutler guide you thorough the maze of the internal politics of modern medicine in finding the physician willing to help you. Then he presents compelling scientific evidence that a large number of people may have a mercury poisoning and describes the current bureaucratic catch-22 preventing the proper requlation of mercury in health care products. Chronic mercury poisoning is described and a rigorous diagnostic procedure is presented so you can determine whether you DO have a problem with mercury, and if not what might ...
Zhang XA, Yates A, Vasilevsky N, Gourdine JP, Callahan TJ, Carmody LC, Danis D, Joachimiak MP, Ravanmehr V, Pfaff ER, Champion J, Robasky K, Xu H, Fecho K, Walton NA, Zhu RL, Ramsdill J, Mungall CJ, Kohler S, Haendel MA, McDonald CJ, Vreeman DJ, Peden DB, Bennett TD, Feinstein JA, Martin B, Stefanski AL, Hunter LE, Chute CG, Robinson PN. Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery. NPJ Digit Med. 2019;2. pii: 32. doi: 10.1038/s41746-019-0110-4. Epub 2019 May 2 ...
Zhang XA, Yates A, Vasilevsky N, Gourdine JP, Callahan TJ, Carmody LC, Danis D, Joachimiak MP, Ravanmehr V, Pfaff ER, Champion J, Robasky K, Xu H, Fecho K, Walton NA, Zhu RL, Ramsdill J, Mungall CJ, Kohler S, Haendel MA, McDonald CJ, Vreeman DJ, Peden DB, Bennett TD, Feinstein JA, Martin B, Stefanski AL, Hunter LE, Chute CG, Robinson PN. Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery. NPJ Digit Med. 2019;2. pii: 32. doi: 10.1038/s41746-019-0110-4. Epub 2019 May 2 ...
Zhang XA, Yates A, Vasilevsky N, Gourdine JP, Callahan TJ, Carmody LC, Danis D, Joachimiak MP, Ravanmehr V, Pfaff ER, Champion J, Robasky K, Xu H, Fecho K, Walton NA, Zhu RL, Ramsdill J, Mungall CJ, Kohler S, Haendel MA, McDonald CJ, Vreeman DJ, Peden DB, Bennett TD, Feinstein JA, Martin B, Stefanski AL, Hunter LE, Chute CG, Robinson PN. Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery. NPJ Digit Med. 2019;2. pii: 32. doi: 10.1038/s41746-019-0110-4. Epub 2019 May 2 ...
Zhang XA, Yates A, Vasilevsky N, Gourdine JP, Callahan TJ, Carmody LC, Danis D, Joachimiak MP, Ravanmehr V, Pfaff ER, Champion J, Robasky K, Xu H, Fecho K, Walton NA, Zhu RL, Ramsdill J, Mungall CJ, Kohler S, Haendel MA, McDonald CJ, Vreeman DJ, Peden DB, Bennett TD, Feinstein JA, Martin B, Stefanski AL, Hunter LE, Chute CG, Robinson PN. Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery. NPJ Digit Med. 2019;2. pii: 32. doi: 10.1038/s41746-019-0110-4. Epub 2019 May 2 ...
Background: The Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Denmark, and TIMEDICO invented and developed the Tempus600®, a pneumatic tube system (PTS). This system is only 2.5 cm in diameter and sends blood tubes directly, without packing before transport. Request forms need not be enclosed, since samples are labeled with patient and barcode ID. At the end of the pipes, a robot receives and places the tubes onto a good laboratory practice (GLP) transport system after the principle of "first in, first out" (FIFO), whereafter the tubes are delivered to centrifuges and analytical equipment. The whole system has decreased the total turnaround time (ToTAT) from 2 to 3 h to ,60 min. The aim of the study was to validate the Tempus600/GLP robot system for the 89 most frequent or critical components. ...
1540 WADK is a radio station located in Newport, RI, in the the United States. The station broadcasts on 1540, and is popularly known as WADK. The station is owned by 3G Broadcasting and offers a News/Talk format.
This course will introduce the student to the concept of safety in the laboratory environment for both patients, co-workers and medical laboratory
Ensure the quality and integrity of your test data by promoting the use of Good Laboratory Practices in your lab. Make sure your lab technicians keep these standards top-of-mind with this fun wall poster!
The responsibility for demonstrating the safety of any new food product on the market lies with the developer of that product. This is also the case for new chemicals and drugs. When an applicant seeks approval for a new GM food, they must provide FSANZ with the evidence that supports the safety of the product. It is a requirement that this data be generated according to quality assurance guidelines that are based on internationally accepted protocols (i.e. validated methodology and procedures that are consistent with Good Laboratory Practice (GLP)) and stand up to external scrutiny (i.e. independent audits and documentation trails). To achieve this, the applicant submits to FSANZ a comprehensive dossier of quality-assured raw experimental data for each GM food. This enables FSANZ to independently assess the data and reach a conclusion about the safety of the food. ...
ENQUIRE NOW ,,. Professional Certification in (Pharma): Certified Pharmaceutical GMP Professional, Certified Pharmaceutical Quality Manager, Certified Pharmaceutical Quality Auditor, Certified Pharmaceutical Quality Technician, Certified Drug Regulatory Affairs Professional, Certified Medical Device Professional, Certified GMP for Medical Devices Professional, Certified GMP for Combination Products Professional, Certified GMP for Blood and Blood Components Professional, Certified GMP for Biological Products Professional, Certified GMP for Cosmetics Professional, Certified GMP for Herbal Medicines Professional, Certified GMP for Herbal Medicines Professional, Certified WHO - GMP Professiona, Certified Data Integrity Professional, Certified Quality by Design (QbD) Professional, Certified Quality Risk Management Professional, Certified Medical Device Professional (CMDP), Certified Good Clinical Practices (GCP), Certified Good Laboratory practice professional(CGLPP). Professional Certification in ...
We are looking for intelligent, motivated, enthusiastic individuals to join our Twist Bioscience Operations Team in San Francisco. The DNA Synthesis Specialist will be responsible for the manufacture of oligonucleotides for downstream processing using Twist Biosciences proprietary process workflow and to meet the Twist production forecast and timelines. The ideal candidate will be driven and will do what it takes to keep DNA synthesis manufacturing on track in a fast paced start-up environment. The DNA Synthesis Specialist will produce oligos according to established SOPs and complete manufacturing batch records to contribute to the daily production schedule. The ideal candidate will work independently, be very neat and organized, have basic knowledge and operation of equipment used in DNA synthesis, contribute to process improvement and documentation, and communicate effectively with peers / management. Knowledge of good laboratory practices (GLPs) is important. The Candidate must be comfortable
The purpose of this paper is to present an approach to assist the user in meeting 21 CFR Part 11 compliance with Analyst ® LC/MS Software version 1.2 and above, including Analyst Software 1.4.1, when used in quantitative studies supporting Good Laboratory Practice (GLP) bioanalytical studies. In this paper, the joint responsibilities between a supplier and its customers to support users 21 CFR Part 11 compliance is outlined.
Good Laboratory Practices should be followed when handling this material. The end user assumes all responsibility for care, custody and control of the material, including its disposal, in accordance with the respective national regulations.. ...
GENEWIZ, Inc. the largest provider of research-based Sanger DNA sequencing services in the United States, today announced an expansion of its Good Laboratory Practices...
20. The subject has any Screening Visit 1 abnormal laboratory value that suggests a clinically significant underlying disease or condition that may prevent the subject from entering the study; or the subject has: creatinine ,1.5 mg/dL, alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) ,2 times the upper limit of normal (×ULN), or total bilirubin ,2.0 mg/dL with AST/ALT elevated above the limits of normal values ...
20. The subject has any Screening Visit 1 abnormal laboratory value that suggests a clinically significant underlying disease or condition that may prevent the subject from entering the study; or the subject has: creatinine ,1.5 mg/dL, alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) ,2 times the upper limit of normal (×ULN), or total bilirubin ,2.0 mg/dL with AST/ALT elevated above the limits of normal values ...
Hair is a distinctly variable material, and the nature of this substrate can have a major impact on laboratory test results. This article discusses hair as a laboratory substrate to provide guidance on minimizing variability and creating optimal test conditions.
Siemens Healthineers have announced the CE Mark and global commercial availability of its Atellica™ Solution - flexible, scalable, automation-ready immunoassay and chemistry analysers. The solution is now available across the globe in Europe, the United States, South America and Asia. The Atellica Solution provides laboratory diagnostics professionals control and simplicity so they can spend more time driving outcomes and less time on operations. “The launch of the game-changing Atellica Solution revolutionises sample management and provides customers....
In the absence of symptomatic hyperglycemia, if a single laboratory test result is in the diabetes range, a repeat confirmatory laboratory test (FPG, A1C, 2hPG in a 75 g OGTT) must be done on another day. It is preferable that the same test be repeated (in a timely fashion) for confirmation, but a random PG in the diabetes range in an asymptomatic individual should be confirmed with an alternate test. In the case of symptomatic hyperglycemia, the diagnosis has been made and a confirmatory test is not required before treatment is initiated. In individuals in whom type 1 diabetes is likely (younger or lean or symptomatic hyperglycemia, especially with ketonuria or ketonemia), confirmatory testing should not delay initiation of treatment to avoid rapid deterioration. If results of two different tests are available and both are above the diagnostic cutpoints, the diagnosis of diabetes is confirmed [Grade D, Consensus ...
Pharmaceutical job vacancy : Associate Director, Clinical Laboratory | Our clinical laboratory activities in the flow cytometry area are growing rapidly, and we are currently looking to add to our scientific team. The Associate Director, Clinical Laboratory will act as a leader in this respective area and will participate in and direct research and development within the laboratory. S/he will aid in the development and growth of the clinical laboratory department and will oversee the implementation of new technologies and instrument platforms in the lab. ...
The Department of Clinical Laboratory Genetics within the Laboratory Medicine Program consists of two laboratories: Genome Diagnostics and Cancer Cytogenetics. The Genetic laboratories specialize in the use of leading edge genetic technologies to diagnose and monitor disease, and to identify biomarkers that can be used for patient management. With over 30,000 tests performed yearly, Laboratory Genetics receives many interesting and challenging cases for genetic assessment from patients at UHN and externally from sites across Ontario and Canada. The laboratories test both inherited and acquired diseases, with a unique specialty in inherited and acquired cancers as the largest clinical cancer genetics testing service in Canada. Our partner Advanced Molecular Diagnostics Laboratory (AMDL) is our translational research arm that supports the validation and assessment of new technologies, and works closely with oncologists and scientists at the Princess Margaret Cancer Center to bring new genomic ...
When using serologic diagnostic tests, they may be qualitative or quantitative. When using a qualitative test, the result is either positive or negative. This makes for easy determination of the sensitivity and specificity of the test when compared to a "Gold" standard. However, if the data obtained from test results are reported on a continuous scale, determination of cutoff points and alteration of that point may lead to tremendous changes in sensitivity, specificity, false negatives and false positives.. We look at a population of animals and we classify them as either healthy or diseased. When examining an antibody response in populations, there will usually be some overlap as animals may appear healthy, but are indeed diseased and vice versa. This result may be due to laboratory error or perhaps a failure in the validation process. When using a continuous scale for the test result, such as ELISA tests, we must establish a cutoff point which will help in the most accurate detection of ...
The analytical goals inferred desirable by a group of clinicians for the imprecisions of a wide range of analytes have been studied by survey. The goals required have not in general become more stringent in the past decade and are not as demanding as those promulgated by laboratory professionals. Clinical biochemistry laboratories can now attain analytical imprecisions which satisfy the general demands of clinicians except for analyses of calcium and of low levels of glucose. The lack of published data on analytical goals does not allow wide comparison of criteria for performance standards with the results of this study.. ...
The QUASIMEME Project (1993-1996) was established to assist European laboratories to improve the data they produce in marine monitoring programmes. Through laboratory performance Studies (with six-monthly reports), workshops and expert visits the programme was fully interactive. There were five rounds of laboratory performance studies. For the nutrient section, in which about 50 laboratories took part, the reference materials distributed to the participants consisted of standard solutions of nutrients and seawater samples stabilized by autoclaving. The material included low and high concentrations typical of those encountered in coastal seawater; at least two samples with different concentrations were distributed in each round. Robust statistics were used to determine the means and standard deviations for each set of results. For inorganic nutrients, the assessment of the data for bias and precision was based mainly on a Z- and P-scoring system in which targets of +/- 6% were allocated to the ...
The Genetic Disease Screening Program of the California Department of Public Health works to protect and improve the health of all Californians. This is the largest screening program in the world and sets the standard in delivering high-quality, cost-effective genetic services to all Californians. The mission of the Genetic Disease Screening Program is "To serve the people of California by reducing the emotional and financial burden of disability and death caused by genetic and congenital disorders.". The Clinical Laboratory Improvement Amendments (CLIA) are federal requirements that regulate laboratory testing and require clinical laboratories to be certificated by their state as well as the Center for Medicare and Medicaid Services (CMS) before they can accept human samples for diagnostic testing. Laboratories can obtain multiple types of CLIA certificates, based on the kinds of diagnostic tests they conduct.. ...
Atlanta, Ga.. Director, Laboratory Quality Management Program, Centers for Disease Control and Prevention. In her role as director of the Laboratory Quality Management Program and interim director of Clinical Laboratory Improvement Amendments (CLIA) at the Centers for Disease Control and Prevention (CDC), Dr. Roberta Barnes Carey is responsible for oversight of the quality management system for the CDC infectious disease laboratories.. Carey joined the Division of Healthcare Quality Promotion at the CDC as chief of the Clinical and Environmental Microbiology Branch in 2004, with responsibility for the reference laboratory overseeing identification and characterization of staphylococci and the anaerobic bacteria, detection of antimicrobial resistance and the investigation of healthcare associated infections. In that capacity, she served as acting director for the Division of Laboratory Systems, which provides technical and scientific oversight for the CLIA regulations that set the federal quality ...
The Global Blood Testing Market is anticipated to reach USD 62.9 billion by 2024, according to a new report by Grand View Research, Inc. Growing adoption of testing and screening methodologies that enhance near patient diagnosis through enhanced blood testing that reduce diagnostic turnaround times and lower hospitals stay durations is a major factor expected to provide lucrative growth in demand for the market.. Federal agencies that play a major role in regulation of genetic tests, including Centers for Medicare and Medicaid Services, Food and Drug Administration, and Federal Trade Commission, have also undertaken initiatives expected to further enhance market usage of Clinical Laboratory Improvement Amendments (CLIA) compliant tests in the market. These steps reinforce the goals set by national governments and the medical fraternities to strengthen early diagnostic capabilities across a number of key geographic regions.. Increasing levels of patient awareness that have been witnessed in a ...
TY - JOUR. T1 - External quality assurance in nongynecologic cytology. T2 - The Australasian experience. AU - Shield, Paul W.. AU - Frost, Felicity. AU - Finnimore, Jo L.. AU - Wright, R. Gordon. AU - Cummings, Margaret C.. PY - 2017/5/1. Y1 - 2017/5/1. N2 - BACKGROUND: The Royal College of Pathologists of Australasia Cytopathology Quality Assurance Program has operated an external quality assurance program in nongynecologic cytopathology since 1993. Glass slide preparations of a wide range of nongynecologic cases were circulated to approximately 200 cytopathology laboratories in 16 countries. METHODS: General nongynecologic cytology cases were manufactured from residual specimens after routine diagnosis. Fine-needle aspiration (FNA) cases were made by sampling fresh tissue and making direct specimens. The majority of cases consisted of both air-dried and fixed preparations. Results returned to laboratories included illustrated case discussions highlighting diagnostic features, key differential ...
HairConfirm is the ideal drug testing solution for parents, employers and individuals in need of a fast and accurate hair drug test that is easy to perform and is cheat proof. This kit tests drug usage by analyzing a hair sample, which allows for a full 90 day drug history report that includes the drug user type and quantities present in hair. Results are available within 2 business days upon receipt of the sample by the lab, and are 100 percent secure and confidential.. Our laboratory is accredited by the Clinical Laboratory Improvement Amendments (CLIA) and all tests are supervised, reviewed and approved by Ph.D. staff scientists; our laboratory staff has experience with over 1.5 million hair tests. Positive results are confirmed via a Gas Chromatography Mass Spectrometry (GC/MS) method, which analyzes and reports back the levels of drugs consumed over a 90 day period (excluding marijuana/THC). There is no chance of adulteration as hair samples cannot be affected by external contaminants like ...
Eekels JJM et al. Essentials A pilot study for External Quality Assessment for testing of HIT is described. The qualitative accordance for the PF4/heparin IgG test was 97.6%. The qualitative accordance for functional HIT tests was considerably lower. External Quality Assessment for functional HIT tests is required. SUMMARY: Objective Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening complication of heparin exposure. Diagnosis is most reliable using a combination of an enzyme immunoassay (EIA) that detects antibodies against platelet factor 4 (PF4)/heparin complexes (antigen assay) and a functional assay that detects platelet-activating properties of the pathogenic HIT antibodies. No External Quality Assessment (EQA) is available for a combination of the tests. Here we report on the results of the first international EQA. Methods The pilot EQA was organized by the Department of Transfusion Medicine, Universitätsmedizin Greifswald, Germany. Six serum samples of ...
a b Barbara H. Estridge, Anna P. Reynolds: Basic Clinical Laboratory Techniques. Cengage Learning, 2011, s. 684. ISBN 978-1-111 ... Clinical Liver Disease". 1(5), 2012. DOI: 10.1002/cld.94. *↑ a b Łukasz Durko, Ewa Małecka-Panas. Krwawienia z przewodu ... a b c Thomas A. Miller: Modern Surgical Care: Physiologic Foundations and Clinical Applications. CRC Press, 2006, s. 530-532. ... a b Thomas A. Miller: Modern Surgical Care: Physiologic Foundations and Clinical Applications. CRC Press, 2006, s. 533. ISBN ...
2009). "New Guidelines for Hemorheological Laboratory Techniques". Clinical Hemorheology and Microcirculation. 42 (2): 75-97. ... Other techniques have been implemented such as photoacoustic measurements. This technique uses a single-pulse laser beam to ... Another experimental technique used to evaluate viscoelasticity consisted of using Ferromagnetism beads bonded to a cells ... Clinical Hemorheology and Microcirculation 30 (2004) 61-75 J. Womersley, Method for Calculation of Velocity, Rate of Flow and ...
Textbook of Assisted Reproductive Techniques: Laboratory and Clinical Perspectives. p. 12. "Celebration of 25 years of IVF". ... "Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice, p601". Springer, New York. ... It was licensed as a technique in Britain in 1991, with the first SUZI birth in the UK taking place in September 1992 at the ... These techniques would eventually be developed into intracytoplasmic sperm injection, while Research Instruments would go on to ...
Textbook of Assisted Reproductive Techniques: Laboratory and Clinical Perspectives. p. 12. CARE John Webster House 1. IN VITRO ... Textbook of Assisted Reproductive Techniques: Laboratory and Clinical Perspectives. pp. 10-2. BBC NEWS , Health , 'I helped ...
Laboratory and Clinical Perspectives. Taylor & Francis. p. 528. ISBN 1-85317-870-5. Scott RT, Toner JP, Muasher SJ, Oehninger S ... Gardner, David K; Weissman, Ariel; Howles, Colin M.; Shoham, Zeev (2001). Textbook of Assisted Reproductive Techniques: ... 136-7 Welcome to Fertell.com "Clinical Guideline, February 2004: Fertility assessment and treatment for people with fertility ... 134-5 Speroff L, Fritz MA (2005). Clinical Gynecologic Endocrinology and Infertility (7th ed.). Philadelphia PA: Lippincott ...
Techniques and Applications for the Clinical Laboratory. Boston MA: Academic Press Inc. ISBN 978-0-12-369428-7. Kan, Y. W.; Lee ... As of 2011[update], some US clinical laboratories nevertheless used assays sold for "research use only". Laboratory processes ... for example Clinical Laboratory Improvement Amendments, Health Insurance Portability and Accountability Act, Good Laboratory ... The clinical laboratory requires high standards of reliability; diagnostics may require accreditation or fall under medical ...
Canick, J (Jun 2012). "Prenatal screening for trisomy 21: recent advances and guidelines". Clinical Chemistry and Laboratory ... Many alternative medical techniques are used in Down syndrome; however, they are poorly supported by evidence.[106] These ... "Clinical Lecture Reports, London Hospital. 3: 259-62. Archived from the original on 2006-06-15. Retrieved 2006-07-14.. ... "Journal of Clinical Neonatology. 1 (1): 6-11. doi:10.4103/2249-4847.92231. PMC 3761984. PMID 24027674.. ...
... clinical laboratory techniques such as neuroimaging, spectroscopy and other computer techniques used in research; advances in ... clinical studies on normal and pathological human behaviour; basic studies in psychiatry and related fields; ... research methodology, including the clinical use of recent research findings. The journal was established in 1961 and is ...
Tietz, Norbert W. (1995). Clinical guide to laboratory tests. WB Saunders. ISBN 978-0-7216-5035-7. [page needed] Pascher, ... surgical technique, PN, and the clinical management of pre and post-transplant patients. Intestine transplantation dates back ... Once donor preparation is accomplished, procurement can begin by utilizing the same standard techniques for all abdominal organ ... Furthermore, terminal ileum recovery from living donors is possible., and a laparoscopic technique is being developed to ...
As a scientist, Hart mastered and applied different techniques to laboratory and clinical research endeavors. He also conducts ... Dean Evan Hart, O.D., M.A., B.S., A.A.S., F.A.A.O. (born November 4, 1957) is a U.S.-based scientist, clinical optometrist, ... clinical epidemiology, microbiology, elemental analysis, and contact lenses. In 2015, Hart ran for Nassau County Legislature on ...
The diagnosis varies from clinical and laboratory techniques to field studies (prevalence, ecological and socioeconomic ... This was followed by the establishment of a "Laboratory for Schisosomiasis Research" in the chemistry building of the National ... Blood bank and various laboratories Affiliated to the hospital is a nursing school which graduated 295 students since 1998 up ... In 1977, the institute was officially affiliated to the Ministry of Scientific Research By June 1978 the TBRI's laboratories ...
Textbook of Assisted Reproductive Techniques, Laboratory and Clinical Perspectives, edited by David K. Gardner, 2001 Galindo, A ... After retrieval, the ova are fertilized by the sperm of the male partner (or sperm donor) in the laboratory, and, after several ... This work established the technical foundation and legal-ethical framework surrounding the clinical use of human oocyte and ... with the eggs being fertilized in the laboratory; more rarely, unfertilized eggs may be frozen and stored for later use. Egg ...
This technique is widely used in clinical laboratories because it is relatively easily automated. It is based on the principle ... Nephelometry is a technique used in immunology to determine the levels of several blood plasma proteins. For example the total ... Clinical Immunology and Seriology 3rd Ed., Stevens, pg 127, F.A. Davis Company. ...
In clinical microbiology laboratories, it is used in combination with other traditional and molecular techniques to identify ... Gram staining is a bacteriological laboratory technique[4] used to differentiate bacterial species into two large groups (gram- ... "Journal of Clinical Microbiology. 45 (4): 1113-1117. doi:10.1128/JCM.02523-06. PMC 1865800. PMID 17301283.. ... Gram devised his technique not for the purpose of distinguishing one type of bacterium from another but to make bacteria more ...
Journal of Clinical Laboratory Analysis. 23 (4): 206-9. doi:10.1002/jcla.20332. PMID 19623657. Zhan P, Suo LJ, Qian Q, Shen XK ... "Simultaneous use of direct and indirect diagnostic techniques in atypical respiratory infections from Chlamydophila pneumoniae ... These clinical results correlate with epidemiological evidence that C. pneumoniae is positively associated with asthma severity ... PLoS Clinical Trials. 1 (2): e11. doi:10.1371/journal.pctr.0010011. PMC 1488900 . PMID 16871333. Hahn DL, Grasmick M, Hetzel S ...
Laboratory techniques: physical chemistry, organic chemistry, clinical chemistry. Repères chronologiques / Jacques Tréfouël ( ... For the next ten years, he served as laboratory chief at the Institute, during which time, he was involved in the synthesis and ... From 1920 to 1928 he worked as an assistant to Ernest Fourneau in the laboratory of medicinal chemistry at the Pasteur ... Techniques de laboratoire : chimie physique, chimie biologique, chimie clinique, 1947 - ...
His most recent textbook is a 4rd[clarification needed] edition of Assisted Reproductive Techniques: Laboratory and Clinical ... "Textbook of Assisted Reproductive Techniques, Fourth Edition (Two Volume Set): Textbook of Assisted Reproductive Techniques ... "Textbook of Assisted Reproductive Techniques". Obgyn.net. Retrieved 14 October 2014. "World Congress on Building Consensus out ... Textbook of Assisted Reproductive Techniques. Books.google.com. Retrieved 14 October 2014. " ...
... importance of assay technique and method of interpretation". The Journal of laboratory and clinical medicine. 139 (2): 72-9. ... clinical features and symptoms of the sample at intake". The Journal of Clinical Psychiatry. 67 (5): 703-11. doi:10.4088/JCP. ... In a clinical sample, it is clear that at the pretreatment step of a patient's recovery, more severe eating disorder symptoms ... While studies are still continuing via the use of various imaging techniques such as fMRI; these traits have been shown to ...
... staining is used in clinical diagnostics and in laboratory research. In clinical diagnostics, immunostaining ... Related techniques are also useful in sub-typing lymphocytes which all look quite similar on light microscopy. In laboratory ... Immunoperoxidase is a type of immunostain used in molecular biology, medical research, and clinical diagnostics. In particular ...
CID (July 2007). "Laboratory Diagnostic Techniques for Entamoeba Species". Clinical Microbiology Reviews. 20 (3): 511-32, table ...
He has trained in research and in clinical and laboratory haematology, many haematologists who have established their own ... Molecular biological techniques were added to the biological, biochemical and immunological research. The Department expanded, ... He established a major Clinical and Laboratory in Haematology Department, teaching both undergraduates and postgraduates. ... He gained a BA degree in Physiology and began clinical studies at The (now Royal) London Hospital in 1957 and qualified in ...
Many clinical laboratories in tertiary hospitals will have menus of over 200 antibodies used as diagnostic, prognostic and ... While this technique utilizes only one antibody and therefore is simple and rapid, the sensitivity is lower due to little ... randomized clinical trials". Clinical Cancer Research. 11 (18): 6598-6607. doi:10.1158/1078-0432.CCR-05-0636. ISSN 1078-0432. ... In immunohistochemical techniques, there are several steps prior to the final staining of the tissue antigen, which can cause a ...
Stanley, Jacqueline (2002). "Section II: Laboratory Techniques; Chapter 12: Precipitation". Laboratory Technique 12-1: Radial ... Part 1" (PDF). Laboratory Medicine. American Society of Clinical Pathologists: Oxford University Press. 9 (7): 23-33. doi: ... Part 2. Application and Interpretation of RID Assays". Laboratory Medicine. American Society of Clinical Pathologists: Oxford ... a comparative evaluation of reported and commercial techniques" (PDF). Clinical Chemistry. U.S.A.: American Association for ...
Textbook of Assisted Reproductive Techniques, Laboratory and Clinical Perspectives, edited by David K. Gardner, 2001[page ... Delvigne A, Rozenberg S (2003). "Review of clinical course and treatment of ovarian hyperstimulation syndrome (OHSS)" (PDF). ...
... first to offer clinical laboratory testing for certain mutations in the BRCA1 and BRCA2 genes which cause hereditary breast ... an important flow-cytometric human sperm separation technique for preconceptual gender selection, which has already produced ... Clinical genetics. 49 (2): 57-8. doi:10.1111/j.1399-0004.1996.tb04327.x. PMID 8740912. Fugger, E.; Black, SH; Keyvanfar, K; ... cancer;[citation needed] developed the important technique of non-surgical sperm aspiration for improved treatment of male ...
Labmate UK and Ireland, a journal for scientists, laboratory managers and chemists employed in pharmaceutical, clinical, ... Microscopy and Micro techniques. www.labmate-online.com LabAsia is read by scientists and laboratory managers across all of ... clinical and food and beverage laboratories . International Labmate has features in each issue on the latest developments in ... WWEM is a specialist event focuses on water monitoring and testing in the laboratory, in the field and in processes. In 2008 ...
Clinical evaluation of the scalp is also important. Symptoms of itching, burning, pain, or tenderness usually signal ongoing ... New diagnostic techniques, such as trichoscopy may be used for non-invasive differential diagnosis of cicatricial alopecia. ... You should discuss any treatment with your dermatologist, who will also explain potential side effects, as well as laboratory ... Cicatricial Alopecia Research Foundation Clinical photos of folliculitis keloidalis from the Cicatricial Alopecia Research ...
In clinical microbiology laboratories, it is used in combination with other traditional and molecular techniques to identify ... Gram staining is a bacteriological laboratory technique used to differentiate bacterial species into two large groups (gram- ... Gram devised his technique not for the purpose of distinguishing one type of bacterium from another but to make bacteria more ... While Gram staining is a valuable diagnostic tool in both clinical and research settings, not all bacteria can be definitively ...
... sample and instrument in clinical healthcare laboratories and pharmaceutical drug discovery and manufacturing laboratories. LIS ... and consultants use proprietary data sources along with various tools and techniques to gather and analyze information. Our ... A laboratory information system (LIS) is an integrated software to manage data and information at all levels in scientific and ... The market for laboratory information system is considered to be mature in developed regions like North America and Europe. The ...
This course will introduce the student to the concept of safety in the laboratory environment for both patients, co-workers and ... This course will introduce the student to the concept of safety in the laboratory environment for both patients, co-workers and ... medical laboratory assistant. This course will explore general safety measures, employee safety and occupational health and ... care and maintenance of common laboratory equipment. ... Clinical Laboratory Techniques. Course Code. MLAB-101. Lecture ...
clinical chemistry*laboratory personnel*laboratory techniques and procedures*point of care systems*laboratories*immunoassay* ... clinical laboratory techniques. Summary. Summary: Techniques used to carry out clinical investigative procedures in the ... Errors in clinical laboratories or errors in laboratory medicine?. Mario Plebani. Department of Laboratory Medicine, University ... Errors in clinical laboratories or errors in laboratory medicine?. Mario Plebani. Department of Laboratory Medicine, University ...
Techniques and Applications for the Clinical Laboratory (9780123694287) and a great selection of similar New, Used and ... 6. Molecular Diagnostics: Techniques and Applications for the Clinical Laboratory Published by Academic Press (2009) ... Molecular Diagnostics: Techniques and Applications for the Clinical Laboratory ISBN 13: 9780123694287. ... 1. Molecular Diagnostics: Techniques and Applications for the Clinical Laboratory (Hardback) Published by Elsevier Science ...
... 0-9. A. B. C. D. E. F. G. H. I. J. K. L. M. N. O. P. ... Laboratory diagnosis of diphtheria / by Androulla Efstratiou and P. A. Christopher Maple  ...
Clinical Laboratory Techniques*Clinical Laboratory Techniques. *Clinical Laboratory Technique. *Laboratory Technique, Clinical ... "Clinical Laboratory Techniques" by people in Harvard Catalyst Profiles by year, and whether "Clinical Laboratory Techniques" ... "Clinical Laboratory Techniques" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Clinical Laboratory Techniques" by people in Profiles. ...
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Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates. J. ... Sanders, E. R. Aseptic laboratory techniques. J. Vis. Exp. (63), e3064 (2012). ... Martinez, R. M., Megli, C. J., Taylor, R. K. Growth and laboratory maintenance of Vibrio cholerae. Curr. Protoc. 6A.1.1-6A.1.6 ... Characterization of Vibrio cholerae O1 El Tor biotype variant clinical isolates from Bangladesh and Haiti, including a ...
Learners and working professionals alike will find BASIC CLINICAL LABORATORY TECHNIQUES an easy-to-understand, reliable ... International Edition demonstrates the techniques involved in basic clinical laboratory procedures, as well as the theories ... this work-text includes step-by-step instruction and worksheets to help users understand laboratory tests and procedures, such ... as specimen collection, types of analysis, laboratory instrumentation, CLIA and OSHA safety protocols, and much more. ...
W/O emulsions for the purpose of clinical and laboratory peptide-based vaccinations have been prepared using the techniques of ... In the setting of a busy pharmacy that prepares peptide-based vaccine emulsions for clinical studies, the vortex technique can ... There is no consensus in the field over which technique would be best to use and no immunological data are available that ... At a suboptimal vaccine dose, the mice vaccinated with a peptide-based vaccine emulsion prepared using the vortex technique had ...
... 0-9. A. B. C. D. E. F. G. H. I. J. K. L. M. N. O. P ... Laboratory quality standards and their implementation  World Health Organization. Regional Office for the Western Pacific ( ... Development of national health laboratory policy and plan  World Health Organization. Regional Office for the Western Pacific ...
Notes on Programming Techniques. * Notes on Programming Techniques D. John Doyle. Pages 1-8 ... the units used for clinical laboratory tests would be those in common use in the United States, (3) the programs would be ... Louis, C. V. Mosby, 1985). Working with clinicians showed me that many were interested in learning about clinical applications ... I decided that a series of small clinical applications programs would be of use to the medical community. At the onset a number ...
Results of search for su:{Clinical Laboratory Techniques} Refine your search. *Availability * Limit to currently available ... Laboratory medicine education in medical schools : guidelines for courses on the effective use of clinical laboratory tests / ... Clinical laboratory management / Lynne S. Garcia, editor in chief ; editors, Vickie S. Baselski ... [et al.].. by Garcia, Lynne ... Book; Format: print Publisher: Geneva : World Health Organization, 2003Other title: Manual of laboratory techniques..Online ...
Bactériologie clinique : techniques de base pour le laboratoire / J. Vandepitte ... [‏et al.]‏  World Health Organization; ... Basic laboratory procedures in clinical bacteriology / J. Vandepitte ... [‏et al.]‏, 2nd ed. ... 2003)‏. Basic laboratory procedures in clinical bacteriology / J. Vandepitte ... [‏et al.]‏, 2nd ed. World Health Organization ... use of the in vitro micro-technique and the in vivo method / by R. L. Kouznetsov ... [‏et al.]‏  World Health Organization; ...
Text book of assisted reproductive techniques laboratory and clinical perspectives , کتابخانه دیجیتال جندی شاپور اهواز ... Text book of assisted reproductive techniques laboratory and clinical perspectives , ... Text book of assisted reproductive techniques laboratory and clinical perspectives [Book]/ edited by David K. Gardner...[et al] ...
More than half of the book is devoted to the clinical interpretation of laboratory examinations. The remainder is given over to ... the practical application of laboratory examinations in clinical diagnosis, to the technic of such examinations and to a 130 ... Techniques for Hemagglutination and Hemagglutination-Inhibition with Arthropod-Borne Viruses D. H. Clarke and J. Casals ... Clinical Diagnosis by Laboratory Examinations By John A. Kolmer. D. Appleton-Century Co. New York and London. 1943 * Elliston ...
A. The Laboratory Diagnosis of Toxoplasmosis. The most precise way in which to gather laboratory support for the diagnosis of ... On this score I would strongly recommend that laboratory-reared mice be used for such attempts, since we have never encountered ... My discussion will be divided into three parts: (a) the laboratory procedures which are considered to be most helpful for ... making the diagnosis of toxoplasmosis; (b) the clinical manifestations of infection with Toxoplasma in humans and animals; (c) ...
Basic Clinical Laboratory Skills and Techniques Teaching Course. 16/01/2018 The course is focussed on providing training to ... Frontiers in Laboratory Medicine 2018. 30/01/2018 Frontiers in Laboratory Medicine 2018- Re-shaping NHS Pathology- a realistic ... UKAS Medical Laboratories Technical Assessor Workshop 2018 17/01/2018 One day annual Technical Assessor Workshop at UKAS ... This is the winter part of the SDVG biannual national clinical virology conference. It brings to the attention of all those ...
a b Barbara H. Estridge, Anna P. Reynolds: Basic Clinical Laboratory Techniques. Cengage Learning, 2011, s. 684. ISBN 978-1-111 ... Clinical Liver Disease". 1(5), 2012. DOI: 10.1002/cld.94. *↑ a b Łukasz Durko, Ewa Małecka-Panas. Krwawienia z przewodu ... a b c Thomas A. Miller: Modern Surgical Care: Physiologic Foundations and Clinical Applications. CRC Press, 2006, s. 530-532. ... a b Thomas A. Miller: Modern Surgical Care: Physiologic Foundations and Clinical Applications. CRC Press, 2006, s. 533. ISBN ...
Basic Clinical Laboratory Techniques. Delmar Publishing. Latest edition. New for 2010-11 - Skills from the Medical Laboratory ... Clinical and/or laboratory stations for selected procedures 2. Holding rooms or areas for competitors 3. Written scenario (one ... MEDICAL LABORATORY ASSISTING * 1. EVENT GUIDELINES Biotechnology Event Guidelines (July 2010) 1 BIOTECHNOLOGY Purpose: To ... Laboratory balance *** Must be provided by student competitor 23. Laminar flow hood 24. Medicine dropper 25. Micropipet 26. ...
Rapid laboratory techniques for the diagnosis of viral infections : report of a WHO scientific group [‎held in Geneva from 29 ... Basic laboratory procedures in clinical bacteriology / J. Vandepitte ... [‎et al.]‎, 2nd ed. dc.contributor.author. Vandepitte ... Basic laboratory procedures in clinical bacteriology / J. Vandepitte ... [‎et al.]‎. en. dc.subject.meshqualifier. standards. ... WHO Scientific Group on Rapid Laboratory Techniques for the Diagnosis of Viral Infections; World Health Organization (‎World ...
Items where Subject is "R Medicine , RB Pathology , Clinical pathology. Laboratory technique" Up a level. ...
Basic Clinical Laboratory Skills and Techniques Teaching Course January 2019. 15/01/2019 ... Frontiers in Laboratory Medicine (FiLM) 2019. 29/01/2019 The essential strategic two day meeting for senior laboratory staff ... Frontiers in Laboratory Medicine (FiLM) is undoubtedly the number one meeting of its kind and brings together the leading ... Menarini Diagnositics UK are hosting an event for NHS laboratory staff to attend. There will be 2 sessions each with the same ...
Clinical Focus. *Clinical Pathology. *Mycobacterium Infections. *Clinical Laboratory Techniques. Academic Appointments. * ... Clinical. Stanford Healthcare Clinical Microbiology Laboratory 3375 Hillview Ave Rm 1602 Palo Alto, CA 94304 *Tel: (650) 736- ... We propose that this assay will allow the routine identification of M. tuberculosis complex members in the clinical laboratory. ... Urine culture with antimicrobial susceptibility testing takes 2-3 days and requires a clinical laboratory. The common use of ...
  • Various LIMS solutions are available to manage information and data at different level such as chromatography data system to manage data related with chromatography techniques, scientific data management system that enables scientific data preservation, accessibility and retrieval of data when needed. (pitchengine.com)
  • TMR's experienced team of analysts, researchers, and consultants use proprietary data sources along with various tools and techniques to gather and analyze information. (pitchengine.com)
  • Use of LIS in a laboratory causes reduction in labor cost that results into reduced operating cost will also help in driving the growth of this market. (pitchengine.com)
  • The market for laboratory information system is considered to be mature in developed regions like North America and Europe. (pitchengine.com)
  • or a Master of Science degree in Microbiology or Immunology, or registration as a Medical Technologist with a nationally recognized certifying agency such as the American Society of Clinical Pathologists, the National Certifying Agency for Medical Laboratory Personnel (NCA), the American Medical Technologist (AMT) or RMT certification with the International Society for Clinical Laboratory Technology (ISCLT) or an equivalent certificate. (ok.gov)
  • Content is useful for exam preparation (MSc,FRCPath) and daily laboratory practice and is complementary to our FRCPath mock practical course held ate a later date. (ibms.org)
  • However, little is known about its real-world clinical impact as used in routine practice.We performed a retrospective cohort study of all patients for whom plasma mNGS (Karius test) was performed for all indications at 5 U.S. institutions over 1.5 years. (stanford.edu)
  • In 10 patients who underwent 16 additional repeated tests, only one was associated with clinical impact.The real-world impact of the Karius test as currently used in routine clinical practice is limited. (stanford.edu)
  • Lecture and laboratory courses in molecular biology, protein purification, tissue culture, Current Good Manufacturing Practice (cGMP), and other topics relevant to the biotech and biopharmaceutical industries help prepare students for fulfilling jobs and careers. (bu.edu)
  • JEM , published monthly, contains research papers and clinical studies as well as articles focusing on the training of emergency physicians and on the practice of emergency medicine. (elsevier.com)
  • The program is aimed at early-career postdoctoral (MD, PhD, DDS, DVM, PharmD, etc.) candidates who have discovered a passion for research and have a desire to translate scientific discoveries or technologic innovations into meaningful human health and clinical practice interventions. (scripps.edu)
  • The regulations summarized here for readers of the MMWR series will affect laboratory practice with the goal of improving and maintaining quality. (cdc.gov)
  • In the United States , the practice of medical genetics includes two different career tracks, both requiring certification by the American Board of Medical Genetics (ABMG): the medical geneticist and the clinical geneticist. (encyclopedia.com)
  • A clinical geneticist is a physician (either a doctor of osteopathy or a medical doctor) involved in all parts of clinical practice related to genetic disorders. (encyclopedia.com)
  • Very few clinical geneticists develop a private practice. (encyclopedia.com)
  • Some large national clinics have entire departments devoted to the practice of medical and clinical genetics. (encyclopedia.com)
  • Physicians are attracted to the practice of clinical genetics for a variety of reasons. (encyclopedia.com)
  • Many enjoy understanding the evolving human gene map, the rapid technological advances in the field, and the opportunity to perform laboratory research as well as practice medicine. (encyclopedia.com)
  • Because the practice of clinical genetics requires a medical degree, students must first receive a bachelor's degree, enrolling in courses that meet medical school admission requirements. (encyclopedia.com)
  • Offers new techniques for solving the tough challenges you encounter in your practice every day with a focus on pediatric orthopaedics, upper extremity and orthopaedic oncology. (ovid.com)
  • Laboratory techniques presently available to aid diagnosis are infrequently used in clinical practice. (clinicaltrials.gov)
  • Institute of Medicine (IOM), Committee on Clinical Practice Guideline. (cytopathology.org)
  • Guideline for Clinical Practice - From Development to Use. (cytopathology.org)
  • Clinical Practice Guideline: Directions for a New Program. (cytopathology.org)
  • Drawing from both theory and practice and supported by extensive clinical and laboratory research, this new full-color edition features four new chapters and updated information in the areas of color and shade matching, light curing, periodontology, digital dentistry and more. (elsevier.com)
  • One of his earliest contributions was to move away from test tubes (hence the term 'test-tube baby') and towards the use of petri dishes with culture medium overlaid with paraffin oil in the practice of clinical embryology, a step which made it more practical when IVF was eventually used to retrieve multiple eggs during ovarian stimulation for the purpose of producing multiple follicles. (wikipedia.org)
  • The bachelor's program in Biomedical Laboratory & Clinical Sciences (BLCS) combines general undergraduate education with special technical training that prepares students for positions in biomedical or clinical research. (bu.edu)
  • Conducted collaboratively with the Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research, the MCTI program is a 2- to 3-year research-centric educational endeavor that is complemented by coursework and a series of seminar-based activities directed at preparing the young investigator for a career as a clinical and/or translational scientist. (scripps.edu)
  • The curriculum of the MCTI KL2 Clinical Scholars Program includes a series of required courses and seminars offered through the graduate program, which is consistently ranked as one of the top 10 graduate schools in the biologic and chemical sciences by US News and World Report . (scripps.edu)
  • Two IgM ELISA capture systems (MAC-ELISA) for diagnosis of acute chikungunya virus (CHIKV) infections, and two Inhibition ELISA Methods (IEM) to measure total antibodies against CHIKV were developed using monoclonal antibodies (mAbs) and hyperimmune serum at the National Virology Laboratory of Nicaragua in 2014-2015. (scielosp.org)
  • Clinical Laboratory Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • In a modern approach to total quality, centered on patients' needs and satisfaction, the risk of errors and mistakes in pre- and post-examination steps must be minimized to guarantee the total quality of laboratory services. (labome.org)
  • For laboratory diagnosis, the method most utilized is microscopic examination of fecal samples, but the immunoenzymatic method is also available. (scielo.br)
  • Investigation of laboratory practices that improve patient safety. (ascls.org)
  • Best Practices, LLC conducted this cross-industry benchmarking study to identify current and evolving approaches for qualitative and quantitative consumer marketing research techniques and tools. (best-in-class.com)
  • Laboratory evaluation and transfusion support of patients with autoimmune hemolytic anemia. (biomedsearch.com)
  • The aim of this study was the evaluation of consistency rate between clinical and histopathological diagnosis of oral malignant tumors of mesenchymal and epithelial origin. (magiran.com)
  • For clinical evaluation of the four serological techniques, 260 paired acute and convalescent phase serum samples of suspected chikungunya cases were used. (scielosp.org)
  • Comprehensive chart review was performed, and standardized assessment of clinical impact of the mNGS based on the treating team's interpretation of Karius results and patient management was established.A total of 82 Karius tests were evaluated, from 39 (47.6%) adults and 43 (52.4%) children and a total of 53 (64.6%) immunocompromised patients. (stanford.edu)
  • Written by distinguished investigators and outstanding faculty, Current Protocols Essential Laboratory Techniques, Second Edition is a great source for beginning scientists who want to develop the skills for a fruitful career in research. (researchandmarkets.com)
  • The 60 nm - 70 nm diameter virion has a phospholipid envelope and a single-stranded positive-sense ribonucleic acid (RNA) genome that encodes three structural and seven nonstructural proteins ( 1 1 Dash M, Mohanty I, Padhi S. Laboratory diagnosis of chikungunya virus: do we really need it? (scielosp.org)
  • Viremia and Clinical Presentation in Nicaraguan Patients Infected with Zika Virus, Chikungunya Virus, and Dengue Virus. (stanford.edu)
  • Laboratory work includes anatomy studies using models and dissections, physiology exercises, and histological observations using microscopes, CD's and websites. (genesee.edu)
  • Most hospitals specializing in pediatric care will also have clinical geneticists on their staff. (encyclopedia.com)
  • 1-9 Numerous hospital-based case series have been reported on the clinical spectrum of pediatric invasive GAS disease and have identified that varicella-zoster virus (VZV) infection commonly precedes these infections, especially in cases of NF. (aappublications.org)
  • Scholars have an opportunity to participate in laboratory rotations during which they learn scientific techniques as they apply to areas such as stem cell research, genome sequencing, informatics, drug discovery, and much more. (scripps.edu)
  • Using their expertise, knowledge, laboratory skills and astute ability to collect and analyze data, these scientists make incalculable contributions to the diagnosis and management of disease. (mu.edu)
  • Journal of the American Academy of Orthopaedic Surgeons (JAAOS) Features current and timely research articles as well as richly illustrated peer-reviewed articles focused on clinical diagnosis and management. (ovid.com)
  • This poses an opportunity for the clinical laboratory to develop a new niche of tests and improve patient care by personalizing therapeutic regimens with MAbs. (asm.org)
  • The rarest type of organ transplantation performed, intestine transplantation is becoming increasingly prevalent as a therapeutic option due to improvements in immunosuppressive regiments, surgical technique, PN, and the clinical management of pre and post-transplant patients. (wikipedia.org)
  • It is the language of the technician or researcher involved in biotechnology, biomedical investigations, or clinical research. (bu.edu)
  • Accumulation and fate of green fluorescent labeled Escherichia coli in laboratory-scale drinking water biofilters. (biomedsearch.com)
  • This study investigated the removal of Escherichia coli cells injected into laboratory-scale biofilters and the role of biofilm in retaining the injected E. coli. (biomedsearch.com)
  • Students can also choose to concentrate in clinical research courses which prepare them for work in the world of clinical trials. (bu.edu)
  • Trial registration Clinical trials NCT00469846 . (bmj.com)
  • Nearly all of our scholars have studied in more than one discipline-for example, completing a translational basic science thesis project while participating in the conception and completion of clinical trials ongoing at our institute. (scripps.edu)