Classical swine fever virus
Classical Swine Fever
African Swine Fever Virus
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
African Swine Fever
A sometimes fatal ASFIVIRUS infection of pigs, characterized by fever, cough, diarrhea, hemorrhagic lymph nodes, and edema of the gallbladder. It is transmitted between domestic swine by direct contact, ingestion of infected meat, or fomites, or mechanically by biting flies or soft ticks (genus Ornithodoros).
Pestivirus
A genus of FLAVIVIRIDAE, also known as mucosal disease virus group, which is not arthropod-borne. Transmission is by direct and indirect contact, and by transplacental and congenital transmission. Species include BORDER DISEASE VIRUS, bovine viral diarrhea virus (DIARRHEA VIRUS, BOVINE VIRAL), and CLASSICAL SWINE FEVER VIRUS.
Border disease virus
Iridoviridae
Yellow fever virus
Viral Vaccines
Rift Valley fever virus
Diarrhea Viruses, Bovine Viral
A group of viruses in the genus PESTIVIRUS, causing diarrhea, fever, oral ulcerations, hemorrhagic syndrome, and various necrotic lesions among cattle and other domestic animals. The two species (genotypes), BVDV-1 and BVDV-2 , exhibit antigenic and pathological differences. The historical designation, BVDV, consisted of both (then unrecognized) genotypes.
Viral Envelope Proteins
Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.
Sus scrofa
Virulence
Palatine Tonsil
Viral Nonstructural Proteins
Viral Structural Proteins
Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). These do not include the proteins encoded in the VIRAL GENOME that are produced in infected cells but which are not packaged in the mature virus particle,i.e. the so called non-structural proteins (VIRAL NONSTRUCTURAL PROTEINS).
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Vero Cells
Virus Replication
Cytopathogenic Effect, Viral
Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysosomal enzymes, changes in cell membrane permeability, diffuse changes in intracellular structures, presence of viral inclusion bodies, and chromosomal aberrations. It excludes malignant transformation, which is CELL TRANSFORMATION, VIRAL. Viral cytopathogenic effects provide a valuable method for identifying and classifying the infecting viruses.
Hemorrhagic Fever Virus, Crimean-Congo
Antibodies, Neutralizing
Base Sequence
Cercopithecus aethiops
Yellow Fever
Amino Acid Sequence
Vaccines, Attenuated
Host-Pathogen Interactions
Rift Valley Fever
An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.
Ornithodoros
Endopeptidases
Reverse Transcriptase Polymerase Chain Reaction
Asfarviridae
Localization of pestiviral envelope proteins E(rns) and E2 at the cell surface and on isolated particles. (1/236)
The glycoproteins E(rns) of classical swine fever virus (CSFV) and E(rns) and E2 of bovine viral diarrhoea virus (BVDV) are shown to be located at the surface of infected cells by the use of indirect immunofluorescence and by cytofluorometric analysis. The positive immunostaining of the cell surface was further analysed by immunogold electron microscopy and it could be shown that only extracellular virions were labelled. Gold granules were not seen at the cellular plasma membrane. In contrast to BVDV E2, the CSFV E2 of virions sticking to the plasma membrane was not accessible to the respective monoclonal antibodies. However, CSFV particles isolated from culture supernatant were able to bind both monoclonal anti-E(rns) and anti-E2 antibodies. For CSFV and BVDV, binding of anti-E(rns) antibodies to the virions was more pronounced than that of anti-E2. This finding was unexpected since E2 is considered to be the immunodominant glycoprotein. (+info)Cytopathogenic and noncytopathogenic RNA replicons of classical swine fever virus. (2/236)
To determine the minimal requirements for autonomous RNA replication of classical swine fever virus (CSFV), genomes having in-frame deletions within the genes for structural and flanking nonstructural proteins were constructed, based on an infectious cDNA clone of CSFV Alfort/187. RNA was transcribed in vitro from the respective plasmids and transfected into SK-6 swine kidney cells. The replication competence of the RNA was determined by immunostaining transfected cells for CSFV NS3 protein and by analysis of cell extracts for viral RNA, as well as protein synthesis at different times after transfection. The genes encoding N(pro), C, E(rns), E1, E2, p7, and NS2 proved to be dispensable for RNA replication, but the efficiency of replication varied strongly between individual constructs. RNA replicons containing the complete NS2-NS3 gene persisted in transfected cells and continued to replicate without causing any obvious morphological or functional damage to the cells, whereas genomes lacking the NS2 gene replicated more efficiently and induced a cytopathic effect. These findings suggest that NS2, although it is not essential for pestivirus RNA replication, has a regulatory function therein. Both cytopathogenic and noncytopathogenic replicons were packaged into virus particles provided in trans by a cotransfected full-length helper virus genome. (+info)Classical swine fever in Sardinia: epidemiology of recent outbreaks. (3/236)
A variable region of the gene encoding the major glycoprotein (E2) of Classical Swine Fever Virus (CSFV) was sequenced from 12 Sardinian isolates which had been obtained from three geographically distinct regions of the Island. Phylogenetic analysis of these viruses and others characterized in previous studies [1, 2] indicated that (a) the Sardinian viruses were all members of the common European subgroup 2.3 and were clearly distinct from live vaccines recently used in this area; (b) they could be resolved into four distinct groups in accordance with the region or date of isolation; (c) in at least two regions wild boar/domestic swine contact was implicated in virus spread; (d) the oldest isolate (1983) and some of the recent isolates were possibly introduced from mainland Italy. In addition, this study has wider implications for the interpretation of CSFV variation. We have been able to demonstrate that small variations within this region of the virus genome (possibly less than 2.7% or five nucleotide substitutions) can be used to separate isolates into groups that precisely fit their geographical distribution. This finding is especially important for deducing the epidemiological relationships between multiple outbreaks caused by similar viruses that occur in close proximity. (+info)Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation. (4/236)
Classical swine fever (CSF) is a severe hemorrhagic disease of swine caused by the pestivirus CSF virus (CSFV). Amino acid exchanges or deletions introduced by site-directed mutagenesis into the putative active site of the RNase residing in the glycoprotein E(rns) of CSFV abolished the enzymatic activity of this protein, as demonstrated with an RNase test suitable for detection of the enzymatic activity in crude cell extracts. Incorporation of the altered sequences into an infectious CSFV clone resulted in recovery of viable viruses upon RNA transfection, except for a variant displaying a deletion of the histidine codon at position 297 of the long open reading frame. These RNase-negative virus mutants displayed growth characteristics in tissue culture that were undistinguishable from wild-type virus and were stable for at least seven passages. In contrast to animals inoculated with an RNase-positive control virus, infection of piglets with an RNase-negative mutant containing a deletion of the histidine codon 346 of the open reading frame did not lead to CSF. Neither fever nor extended viremia could be detected. Animals infected with this mutant did not show decrease of peripheral B cells, a characteristic feature of CSF in swine. Animal experiments with four other mutants with either exchanges of codons 297 or 346 or double exchanges of both codons 297 and 346 showed that all these RNase-negative mutants were attenuated. All viruses with mutations affecting codon 346 were completely apathogenic, whereas those containing only changes of codon 297 consistently induced clinical symptoms for several days, followed by sudden recovery. Analyses of reisolated viruses gave no indication for the presence of revertants in the infected animals. (+info)The RNA-dependent RNA polymerases of different members of the family Flaviviridae exhibit similar properties in vitro. (5/236)
The virus-encoded RNA-dependent RNA polymerase (RdRp), which is required for replication of the positive-strand RNA genome, is a key enzyme of members of the virus family Flaviviridae. By using heterologously expressed proteins, we demonstrate that the 77 kDa NS5B protein of two pestiviruses, bovine viral diarrhoea virus and classical swine fever virus, and the 100 kDa NS5 protein of the West Nile flavivirus possess RdRp activity in vitro. As originally shown for the RdRp of hepatitis C virus, RNA synthesis catalysed by the pestivirus and flavivirus enzymes is strictly primer-dependent in vitro. Accordingly, initiation of RNA polymerization on homopolymeric RNAs and heteropolymeric templates, the latter with a blocked 3'-hydroxyl group, was found to be dependent on the presence of complementary oligonucleotide primer molecules. On unblocked heteropolymeric templates, including authentic viral RNAs, the RdRps were shown to initiate RNA synthesis via intramolecular priming at the 3'-hydroxyl group of the template and 'copy-back' transcription, thus yielding RNase-resistant hairpin molecules. Taken together, the RdRps of different members of the Flaviviridae were demonstrated to exhibit a common reactivity profile in vitro, typical of nucleic acid-polymerizing enzymes. (+info)Classical swine fever virus E(rns) deletion mutants: trans-complementation and potential use as nontransmissible, modified, live-attenuated marker vaccines. (6/236)
An SK6 cell line (SK6c26) which constitutively expressed the glycoprotein E(rns) of classical swine fever virus (CSFV) was used to rescue CSFV E(rns) deletion mutants based on the infectious copy of CSFV strain C. The biochemical properties of E(rns) from this cell line were indistinguishable from those of CSFV E(rns). Two E(rns) deletion mutants were constructed, virus Flc23 and virus Flc22. Virus Flc23 encoded only the utmost N- and C-terminal amino acids of E(rns) (deletion of 215 amino acids) to retain the original protease cleavage sites. Virus Flc22 is not recognized by a panel of E(rns) antibodies, due to a deletion of 66 amino acids in E(rns). The E(rns) deletion mutants Flc22 and Flc23 could be rescued in vitro only on the complementing SK6c26 cells. These rescued viruses could infect and replicate in SK6 cells but did not yield infectious virus. Virus neutralization by E(rns)-specific antibodies was similar for the wild-type virus and the recombinant viruses, indicating that E(rns) from SK6c26 cells was incorporated in the viral particles. Pigs vaccinated with Flc22 or Flc23 were protected against a challenge with a lethal dose of CSFV strain Brescia. This is the first demonstration of trans-complementation of defective pestivirus RNA with a pestiviral structural protein and opens new ways to develop nontransmissible modified live pestivirus vaccines. In addition, the absence of (the antigenic part of) E(rns) in the recombinant viral particles can be used to differentiate between infected and vaccinated animals. (+info)Pathogenesis of granulocytopenia and bone marrow atrophy during classical swine fever involves apoptosis and necrosis of uninfected cells. (7/236)
Granulocytopenia, a hematological hallmark of classical swine fever, is partially responsible for the suppression of innate immune defenses during classical swine fever. The present report demonstrates that this depletion was apparent as early as 3 days postinfection (p.i.). Both mature peripheral and bone marrow neutrophils were affected, whereas immature neutrophils increased absolutely in the periphery and coincidentally immature myeloid progenitors in the bone marrow. These data suggest that a pathogenic relationship exists between these compartments. The central event was not the arrest of hematopoietic cell proliferation or of the mobilization process, but instead apoptosis and possibly also necrosis were shown to play a role. This increase in apoptotic and dead cells was detected as early as 1-3 days p.i. In contrast, viral RNA in bone marrow hematopoietic cells (BMHC) was first detected 5 days p.i., and significant amounts of infected BMHC were detected only 7 days p.i., with the major target being the myeloid compartment. The increased caspase-3 activity observed supported a role for apoptotic cell death. Furthermore, the elevated caspase-9 activity indicated the involvement of the mitochondrial apoptotic pathway. Taken together, the results demonstrate that granulocytopenia and bone marrow atrophy are mediated by hematopoietic cell death and that indirect virus-host-mediated mechanisms are likely to be responsible. (+info)Ultrastructural glomerular changes in experimental infection with the classical swine fever virus. (8/236)
Ultrastructural studies of glomerular changes were performed on 16 pigs experimentally infected with a highly virulent strain of the classical swine fever virus. Our observations revealed the thickening of glomerular basement membranes, swelling of endothelial cells and cytoplasmic vacuolization within podocytes containing abundant viral particles. An early viral infection of podocytes was suggested as the cause of selective swelling of the foot processes of these cells with the consequent obliteration of the glomerular urinary spaces. To our knowledge this is the first report of ultrastructural evidence of classical swine fever virions infecting glomerular podocytes. (+info)
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EC 3.4.21.113
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Pt.fieldcrop.
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MTA ÁOTI
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SNX8
"U18666A inhibits classical swine fever virus replication through interference with intracellular cholesterol trafficking". ... Finally, SNX8 also plays an antiviral role against RNA viruses such as SeV (Sendai virus) through VISA-mediated activation of ... In addition, SNX8 plays an antiviral role against DNA viruses such as HSV-1 through the MITA-mediated activation of the IFNβ ... SNX8 is a key component in the induction of downstream effector antiviral gene transcription in response to RNA viruses, as it ...
Aphthovirus internal ribosome entry site (IRES)
"Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ...
Pestivirus internal ribosome entry site (IRES)
The classical swine fever virus UTR described appears to be longer at the 5' end than other pestivirus UTRs. This family ... "Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ...
Tobamovirus internal ribosome entry site (IRES)
"Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ...
Hepatitis A virus internal ribosome entry site (IRES)
"Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ... nontranslated region of hepatitis A virus RNA: comparison with the IRES of encephalomyocarditis virus". Journal of Virology. 68 ... For influenza A virus, its primary method of action as an antiviral is to prevent the uncoating of viral genome which inhibits ... This results in a longer period required until maximum shedding of the virus is reached. This also results in cell death only ...
Plum Island Animal Disease Center
The principal diseases studied are foot-and-mouth disease, classical swine fever, and vesicular stomatitis virus.[citation ... including classical swine fever and African swine fever. PIADC runs about 30,000 diagnostic tests each year. PIADC operates ... 2008). Germs, viruses, and secrets: government plans to move exotic disease research to the mainland United States: hearing ... Because federal law stipulates that live foot-and-mouth disease virus cannot be studied on the mainland, PIADC is unique in ...
PRR29
... interacting protein involved in classical swine fever virus growth". Journal of Virology. 87 (4): 2072-80. doi:10.1128/JVI. ... study found that a Sus scrofa PRR29-like protein interacts with the N-terminal protease of classical swine fever virus (CSFV). ...
Pestivirus NS3 polyprotein peptidase
... bovine viral diarrhea virus NS3 endopeptidase, BVDV NS3 endopeptidase, classical swine fever virus NS3 endopeptidase, CSFV NS3 ... Xu J, Mendez E, Caron PR, Lin C, Murcko MA, Collett MS, Rice CM (July 1997). "Bovine viral diarrhea virus NS3 serine proteinase ... Tautz N, Kaiser A, Thiel HJ (August 2000). "NS3 serine protease of bovine viral diarrhea virus: characterization of active site ... Pestivirus NS3 polyprotein peptidase (EC 3.4.21.113, border disease virus NS3 endopeptidase, BDV NS3 endopeptidase, ...
National Centre for Foreign Animal Disease
Nipah virus infection, Rift Valley fever, capripox, lumpy skin disease, glanders, and classical swine fever. Animal Care - The ... Diseases of primary concern are: classical swine fever, African swine fever, Newcastle disease, and notifiable avian influenza ... classical swine fever, and Nipah and Hendra virus infections. The NCFAD has received designations by the World Organization for ... Hendra virus, Ebola virus and Rift Valley fever virus. The Section maintains a state of readiness for emergencies or outbreak ...
Senecavirus
... including classical swine fever virus, and Hepacivirus genus, including Hepatitis C virus. The SVV IRES RNA shares similarities ... Positive stranded RNA virus transcription is the method of transcription. The virus exits the host cell by lysis, and ... "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 20 May 2021. Reddy ... Structure of Seneca Valley Virus-001 - on Virus Particle ExploreR (VIPERdb) Viralzone: Senecavirus ICTV (CS1 errors: missing ...
Pestivirus
Bovine viral diarrhea virus type 2 (BVDV-2), Border disease virus (BDV), and Classical swine fever (CSF) virus are the four ... causes Bovine viral diarrhea and Mucosal disease Pestivirus C or Classical swine fever virus (CSFV), causes Classical swine ... "Identification of an NTPase motif in classical swine fever virus NS4B protein". Virology. 411 (1): 41-49. doi:10.1016/j.virol. ... "Establishment of a Dual SYBR Green I Fluorescence PCR Assay for African Swine Fever Virus and Porcine Epidemic Diarrhea Virus ...
Model organism
... feline immunodeficiency virus (FIV), tuberculosis, Texas cattle fever, classical swine fever (hog cholera), heartworm, and ... Virus-typing of polio by Salk "Tireless polio research effort bears fruit and indignation". Archived from the original on 2008- ... Salk polio virus [2] History of polio vaccine "the work on [polio] prevention was long delayed by... misleading experimental ... In the 1940s, Jonas Salk used rhesus monkey studies to isolate the most virulent forms of the polio virus, which led to his ...
History of animal testing
Feline immunodeficiency virus (FIV), tuberculosis, Texas cattle fever, Classical swine fever (hog cholera), Heartworm and other ... Virus-typing of polio by Salk [6] Salk polio virus [7] History of polio vaccine ""the work on [polio] prevention was long ... In the 1940s, Jonas Salk used rhesus monkey cross-contamination studies to isolate the three forms of the polio virus that ... Albert Sabin made a superior "live" vaccine by passing the polio virus through animal hosts, including monkeys. The vaccine was ...
ATCvet code QI09
... virus QI09AD03 Porcine reproductive and respiratory syndrome (PRRS) virus QI09AD04 Classical swine fever virus QI09AE01 ... porcine influenza virus QI09AA05 Porcine reproductive and respiratory syndrome (PRRS) virus QI09AA06 Classical swine fever ... QI09AA01 Aujeszky's disease virus QI09AA02 Porcine parvovirus QI09AA03 Porcine influenza virus QI09AA04 Aujeszky's disease ... erysipelothrix QI09AL04 Porcine influenza virus + erysipelothrix QI09AL05 Porcine transmissible gastro-enteritis virus + ...
Bovine viral diarrhea
Other members of this genus cause Border disease (sheep) and classical swine fever (pigs) which cause significant financial ... Ncp viruses can induce persistent infection in cells and have an intact NS2/3 protein. In cp viruses the NS2/3 protein is ... Animal viruses Fray, M.D; Paton, D.J; Alenius, S.; et al. (2000). "The effects of bovine viral diarrhoea virus on cattle ... The virus, therefore, entered the fetal cells and, during immune system development, was accepted as self. In PIs the virus ...
Veterinary virology
African swine fever virus (ASFV) is a large double-stranded DNA virus which replicates in the cytoplasm of infected cells and ... They cause Classical swine fever (CSF) and Bovine viral diarrhea(BVD). Mucosal disease is a distinct, chronic persistent ... West Nile virus, Israel turkey meningoencephalomyelitis virus, Sitiawan virus, Wesselsbron virus, yellow fever virus and the ... Flaviviruses include the West Nile virus, dengue virus, Tick-borne Encephalitis Virus, Yellow Fever Virus, and several other ...
Howard Bachrach
... then returned to Minnesota and studied classical swine fever (also known as hog cholera). Bachrach found that the disease could ... Bachrach was able to purify the virus responsible for foot-and-mouth disease. In 1950, having spent a year in Europe, Bachrach ... The other 90% of the specimen was "gunk" from the cells involved in the process of growing the virus, but no previous ... "Howard Bachrach, pioneer in fight against polio and other viruses". Star Tribune. July 25, 2008. Retrieved June 2, 2016. George ...
Classical swine fever
International Committee on Taxonomy of Viruses. Retrieved 21 August 2019. ...Classical swine fever virus becomes Pestivirus C ... Classical Swine Fever, Iowa State University Species Profile - Classical Swine Fever, National Invasive Species Information ... "Classical Swine Fever-An Updated Review". Viruses. MDPI. 9 (4): 86. doi:10.3390/v9040086. PMC 5408692. PMID 28430168. Paton, D. ... Classical swine fever (CSF) or hog cholera (also sometimes called pig plague based on the German word Schweinepest) is a highly ...
List of MeSH codes (B04)
... classical swine fever virus MeSH B04.909.777.411 - hepatitis delta virus MeSH B04.909.777.415 - hepatitis e virus MeSH B04.909. ... diarrhea virus 2, bovine viral MeSH B04.820.250.700.400 - classical swine fever virus MeSH B04.820.410.050 - allolevivirus MeSH ... yellow fever virus MeSH B04.820.250.400 - gb virus a MeSH B04.820.250.405 - gb virus b MeSH B04.820.250.410 - GB virus C MeSH ... rift valley fever virus MeSH B04.820.087.710.750 - sandfly fever naples virus MeSH B04.820.087.710.900 - uukuniemi virus MeSH ...
Foreign animal disease
"African Swine Fever Summary sheets" (PDF). "Classical Swine Fever" (PDF). August 2008. "Classical Swine Fever (hog cholera) ... "With high virulent forms of the virus, ASF is characterized by high fever, loss of appetite, hemorrhages in the skin and ... Lesions of classical swine fever are clinico-pathologically indistinguishable from African swine fever; it is essential to send ... Classical swine fever was once widespread, but has been eradicated from many countries from domestic swine, including the US. A ...
Vaccine
... such as classical swine fever, avian influenza, Actinobacillus pleuropneumonia and Salmonella infections in pigs. Prior to the ... Eggs were used for virus propagation in the development of a yellow fever vaccine in 1935 and an influenza vaccine in 1945. In ... "Glycoprotein E1 of hog cholera virus expressed in insect cells protects swine from hog cholera". Journal of Virology. 67 (9): ... Viruses are grown either on primary cells such as chicken eggs (e.g., for influenza) or on continuous cell lines such as ...
African swine fever virus
The clinical symptoms of ASFV infection are very similar to classical swine fever, and the two diseases normally have to be ... Wikispecies has information related to African swine fever virus. Canadian Food Inspection Agency African swine fever ... Viruses portal Veterinary virology Dixon; et al. (2008). "African Swine Fever Virus". Animal Viruses: Molecular Biology. ... African swine fever virus (ASFV) is a large, double-stranded DNA virus in the Asfarviridae family. It is the causative agent of ...
Betaarterivirus suid 1
"Negative impact of porcine reproductive and respiratory syndrome virus infection on the efficacy of classical swine fever ... simian hemorrhagic fever virus (SHFV), wobbly possum disease virus, and lactate dehydrogenase elevating virus (LDV). PRRSV is a ... virus isolate and the virus dose. It was shown that pigs could be infected with PRRS virus by several routes of exposure: ... immune response to swine influenza virus challenge in pigs infected with porcine reproductive and respiratory syndrome virus at ...
List of biosafety level 4 organisms
... formerly Classical swine fever virus) Foot-and-mouth disease virus Goatpox virus Lumpy skin disease virus Avian avulavirus 1 ( ... Rift Valley fever phlebovirus Venezuelan equine encephalitis virus African horse sickness virus African swine fever virus Avian ... formerly peste des petits ruminants virus) Rinderpest morbillivirus Sheeppox virus Swine vesicular disease virus Andes ... Far Eastern subtype Flavivirus Siberian subtype Flavivirus Kyasanur Forest disease virus Omsk hemorrhagic fever virus Variola ...
Wildlife disease
... modelling classical swine fever incursions in wild pigs in Australia". Veterinary Research. 43 (1): 3. doi:10.1186/1297-9716-43 ... Contemporary diseases of zoonotic origin include SARS, Lyme disease and West Nile virus. Disease emergence and resurgence in ... red grouse and louping ill virus". Journal of Applied Ecology. 47 (4): 926-930. doi:10.1111/j.1365-2664.2010.01834.x. ISSN 1365 ...
Flaviviridae
... bovine viral diarrhea virus 1) and Pestivirus C (classical swine fever virus, previously hog cholera virus)). Viruses in this ... Yellow fever virus, and Zika virus) Genus Hepacivirus (includes Hepacivirus C (hepatitis C virus) and Hepacivirus B (GB virus B ... Guaico Culex virus, Jingmen tick virus and Mogiana tick virus. These viruses have a segmented genome of 4 or 5 pieces. Two of ... These include Wenling shark virus. Jingmenvirus is a group of unclassified viruses in the family which includes Alongshan virus ...
Select agent
African horse sickness virus African swine fever virus Avian influenza virus (highly pathogenic) Classical swine fever virus ... viruses: African VHF viruses: Crimean-Congo hemorrhagic fever virus Ebola virus* Lassa fever virus Lujo virus Marburg virus* ... Asian VHF viruses: Kyasanur Forest disease virus Omsk hemorrhagic fever virus South American VHF viruses: Chapare virus ... Hendra virus Nipah virus Rift Valley fever virus Venezuelan equine encephalitis virus (excluding enzootic subtypes ID and IE) ...
List of MeSH codes (C22)
... african swine fever MeSH C22.905.170 - classical swine fever MeSH C22.905.260 - edema disease of swine MeSH C22.905.323 - ... marburg virus disease MeSH C22.735.500.850 - simian acquired immunodeficiency syndrome MeSH C22.735.750 - monkeypox MeSH ... swine erysipelas MeSH C22.905.850 - swine vesicular disease MeSH C22.905.927 - vesicular exanthema of swine The list continues ... of swine MeSH C22.905.626 - pneumonia of swine, mycoplasmal MeSH C22.905.700 - porcine reproductive and respiratory syndrome ...
Pseudorabies
... disease is considered to be the most economically important viral disease of swine in areas where classical swine fever (hog ... The virus is shed in the saliva and nasal secretions of swine infected by the respiratory route. Aerosolization of the virus ... Swine (both domestic and feral) are usual reservoirs for this virus, though it does affect other species. Aujeszky's disease ... Diagnosis is made mainly by virus isolation in tissue cultures, or through ELISA or PCR tests. Vaccines are available for swine ...
Animal husbandry
Some, like classical swine fever and scrapie are specific to one type of stock, while others, like foot-and-mouth disease ... This virus is easily transmissible to domestic poultry, and to humans living in close proximity with them. Other infectious ... "Classical swine fever" (PDF). The Center for Food Security and Public Health. Retrieved 20 May 2017. "Scrapie Fact Sheet". ... An outbreak of Nipah virus in Malaysia in 1999 was traced back to pigs becoming ill after contact with fruit-eating flying ...
History of medicine
... the Influenza A virus subtype H5N1 from 2004, the Ebola virus epidemic in West Africa and onwards. Mary Putnam Jacobi (1842- ... Known as swine flu, due to its indirect source from pigs, it went on to infect over 700 million people. The continuing HIV ... Harvard: Loeb Classical Library. Vallance JT (April 1993). "Herophilus: The Art of Medicine in Early Alexandria". Ancient ... In 1847 in Vienna, Ignaz Semmelweis (1818-1865), dramatically reduced the death rate of new mothers (due to childbed fever) by ...
Columbia, Tennessee
Marion Dorsett, discovered in 1903 that swine fever (hog cholera) was caused by a virus; in 1935 he helped develop the crystal ... Private schools include Agathos Classical School, Zion Christian Academy and Columbia Academy. The city is home to the main ... that hog cholera is caused by an ultramicroscopic virus, and hogs recovered from the disease are immune for life." Sterling, ...
Biological warfare
Machupo virus, Coronaviruses (especially SARS-Cov-2 that causes COVID-19), Marburg virus, Variola virus, and yellow fever virus ... African swine fever for pigs, and psittacosis to kill the chicken. These agents were prepared to spray them down from tanks ... It is important to note that most classical and modern biological weapons' pathogens can be obtained from a plant or an animal ... especially Rift Valley fever virus), Ebolavirus, many of the Flaviviridae (especially Japanese encephalitis virus), ...
W. Ian Lipkin
"Ian Lipkin The Virus Hunter" (PDF). Discover. April 2012. Zimmer, Carl (November 22, 2010). "A Man From Whom Viruses Can't Hide ... Within this consortium, his research focused on pathogen discovery, using unexplained hemorrhagic fever, febrile illness, ... such as swine. Lipkin addressed a health forum in Guangzhou in January 2004 where China Daily reported him as saying: "SARS ... "classical gumshoe epidemiology" of "contact tracing and isolation" that brought swift action against the epidemic. Lipkin was ...
Wan Chai
... suspected of being infected or in contact with the H1N1 virus during the global outbreak of swine flu. A 25-year-old Mexican ... It taught classical Chinese writings and Confucian ethics. In 1936, the Chinese Methodist Church (香港基督教循道衛理教會) moved its ... Every year the academy produces a number of Broadway musicals, including Singin' in the Rain, Saturday Night Fever, and Annie. ... "Swine flu scare: China puts 460 in isolation", The Times of India, 3 May 2009. "A historical and architectural appraisal of ...
History of West Africa
Jihad fever swept northern Nigeria, with strong support among both the Fulani and the Hausa. Usman created an empire that ... The outbreak is caused by the Zaire ebolavirus, known simply as the Ebola virus (EBOV). It is the most severe outbreak of Ebola ... This is a legal designation used only twice before (for the 2009 H1N1 (swine flu) pandemic and the 2014 resurgence of polio) ... As part of this simulated narrative, post-classical Egypt has also been characterized as having plantations. Another part of ...
Table 1 - Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus - Volume 21, Number 4-April 2015 -...
BDV, border disease virus; CSFV, classical swine fever virus.. †CSFV strains: Alfort187 (genotype 1.1), Diepholz (genotype 2.3 ... Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus Alexander Postel, Stefanie Schmeiser, Tuba Cigdem ... Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus. ... Boxes indicate virus neutralization test titers for homologous serum; boldface indicates results for Aydin/04 and Burdur/05. ...
Classical Swine Fever Virus Antibody (IgG) ELISA Kit | CSB-E12765p | Cusabio
Classical Swine Fever Virus Antibody (IgG) ELISA Kit from Cusabio. Cat#: CSB-E12765p. US, UK & Europe Distribution. Online ... Classical Swine Fever Virus Antibody (IgG) ELISA Kit , CSB-E12765p Cusabio Elisa Classical Swine Fever Virus Antibody (IgG) ... Classical Swine Fever Virus Antibody (IgG) ELISA Kit , CSB-E12765p. Rating Required Select Rating. 1 star (worst). 2 stars. 3 ... Classical Swine Fever Virus Antibody (IgG) ELISA Kit is Available at Gentaur Genprice with the fastest delivery. ...
Classical Swine Fever Virus E2 Protein | AG05-0313-Z | Immunology Consultatnt Laboratory
Classical Swine Fever Virus E2 Protein. Catalogue Numbre: AG05-0313-Z, Supplied by Immunology Consultatnt Laboratory& ... Classical Swine Fever Virus E2 Protein , AG05-0313-Z Immunology Consultant Laboratory Classical Swine Fever Virus E2 Protein , ... Classical Swine Fever Virus E2 Protein , AG05-0313-Z , Immunology Consultatnt Laboratory ... Classical Swine Fever Virus E2 Protein , AG05-0313-Z. Rating Required Select Rating. 1 star (worst). 2 stars. 3 stars (average) ...
Development and Application of a High Sensitivity Immunochromatographic Test Strip for Detecting Classical Swine Fever Virus...
... is caused by classical swine fever virus (CSFV) and has lead huge losses to the pig industry worldwide. Although vaccination ... Background: Classical swine fever (CSF) is caused by classical swine fever virus (CSFV) and has lead huge losses to the pig ... Development and Application of a High Sensitivity Immunochromatographic Test Strip for Detecting Classical Swine Fever Virus ... No cross reaction with other swine virus antibodies was observed. The detection of clinical swine serum samples (n=138) ...
Diagnosis of classical swine fever virus in a limited resource setting: The influence of pig breed on methodology and sample...
Humoral and cellular immune response in mice induced by the classical swine fever virus E2 protein fused to the porcine CD154...
Humoral and cellular immune response in mice induced by the classical swine fever virus E2 protein fused to the porcine CD154 ... Humoral and cellular immune response in mice induced by the classical swine fever virus E2 protein fused to the porcine CD154 ... Humoral and cellular immune response in mice induced by the classical swine fever virus E2 protein fused to the porcine CD154 ... and cellular immune response elicited in inbred BALB/c mice by immunization with a recombinant classical swine fever virus ( ...
Table 2 - Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus - Volume 21, Number 4-April 2015 -...
BDV, border disease virus; CSFV, classical swine fever virus; boxes indicate virus neutralization test titers for homologous ... Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus Alexander Postel, Stefanie Schmeiser, Tuba Cigdem ... Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus. ...
Classical swine fever virus vs. Classical swine fever virus: The superinfection exclusion phenomenon in experimentally infected...
T1 - Classical swine fever virus vs. Classical swine fever virus. T2 - The superinfection exclusion phenomenon in ... Classical swine fever virus vs. Classical swine fever virus: The superinfection exclusion phenomenon in experimentally infected ... Classical swine fever virus vs. Classical swine fever virus: The superinfection exclusion phenomenon in experimentally infected ... title = "Classical swine fever virus vs. Classical swine fever virus: The superinfection exclusion phenomenon in experimentally ...
A kit and testing methods for the detection of classical swine fever virus
Publications at this Location : USDA ARS
Antibody Responses of Pigs to Defined Erns Fragments after Infection with Classical Swine Fever Virus
Passage of classical swine fever virus in cultured swine kidney cells selects virus variants that bind to heparan sulfate due ... Classical swine fever virus (CSFV) is an enveloped positive-stranded RNA virus (20) of the genusPestivirusof the Flavi-viridae ... Interaction of classical swine fever virus with mem-brane-associated heparan sulfate: role for virus replication in vivo and ... RNase of classical swine fever virus: biochemical characteriza-tion and inhibicharacteriza-tion by virus-neutralizing ...
Immunomodulatory effect of plasmids co-expressing cytokines in classical swine fever virus subunit gp55/E2-DNA vaccination |...
... of the pestivirus classical swine fever virus lead to virus attenuation, J. Virol. 73 (1999) 10224-10235. [PubMed]. . ... Classical swine fever virus replicon particles lacking the E$^{\rm rns}$ gene: a potential marker vaccine for intradermal ... Dong X.N., Wie K., Liu Z.Q., Chen Y.H., Candidate peptide vaccine induced protection against classical swine fever virus, ... Humoral and cell-mediated immune responses of d/d histocompatible pigs against classical swine fever (CSF) virus Vet. Res. 34, ...
The Unique Glycosylation at Position 986 on the E2 Glycoprotein of Classical
Swine Fever Virus Is Responsible for Viral...
Rabbit Anti-Rift Valley Fever (RVFV) | 494-01-0001
Rabbit Anti-Rift Valley Fever (RVFV) Manufactured by Gentaur. Gentaur is the biggest antibody manufacturer worldwide. ... Rabbit Anti-classical Swine fever Virus , Gentaur MSRP: Was: Now: €340.00 Quick view. Add to Cart The item has been added ... Decrease Quantity of Rabbit Anti-Rift Valley Fever (RVFV) , Gentaur Increase Quantity of Rabbit Anti-Rift Valley Fever (RVFV ... Rabbit Anti-Rift Valley Fever (RVFV) , Gentaur. Rating Required Select Rating. 1 star (worst). 2 stars. 3 stars (average). 4 ...
Frontiers | Consumer acceptance of new food trends resulting from the fourth industrial revolution technologies: A narrative...
Genetically modified pigs are protected from classical swine fever virus. PLoS Pathog. (2018) 14:e1007193. doi: 10.1371/journal ... CRISPR-Cas9 has been used to knock-in resistance to the classical swine fever virus (CSFV) at the Rosa26 gene. This locus is a ... Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus. Nat Biotechnol. (2016) 20-2. doi: ...
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Could feed be spreading classical swine fever, pseudorabies? | The Pig Site
Currently, U.S. commercial swine are free of both classical swine fever virus and pseudorabies virus because of costly ... "The emerging threat of classical swine fever virus and pseudorabies virus being reintroduced into U.S. commercial swine is ... "Classical swine fever virus and pseudorabies virus cause two of the top four transboundary animal diseases of importance to ... When looking at classical swine fever virus, two of the 12 ingredients had infectious virus detected: conventional soybean meal ...
Virology Journal | Articles
African swine fever virus and atypical porcine pestivirus Classical swine fever (CSF), African swine fever (ASF), and atypical ... Development of a quadruple PCR-based gene microarray for detection of vaccine and wild-type classical swine fever virus, ... Hepatitis delta virus (HDV), a satellite virus of hepatitis B virus (HBV), is a small, defective RNA virus strongly associated ... As the virus evolves, so too must we: a drug developers perspective The SARS-CoV-2 virus has been raging globally for over 2 ...
Medizinische Hochschule Hannover : Alumni Profiles
Research Topic: Epitope mapping of the Classical Swine Fever Virus glycoprotein E2. Supervisor: Prof. Dr. Volker Moennig, ... Research Topic: Interaction of hepatitis B virus - hepatitis Delta Virus co-infection in a humanized mouse model. Supervisor: ... Research Topic: Infection of the respiratory epithelium by Canine distemper virus: importance of lipid rafts for virus entry ... Research Topic: Hepatitis C Virus - Human Immunodeficiency Virus Coinfection: Immune Mechanisms, Viral Interactions and ...
Previous editions of the Terrestrial Code - WOAH - World Organisation for Animal Health
Infection with peste des petits ruminants virus. - Infection with classical swine fever virus Adopted amendments Proposed ... Infection with peste des petits ruminants virus (Chapter 14.7.). - Infection with classical swine fever virus (Chapter 15.2.). ... African swine fever. - Classical swine fever (CSF). - Avian influenza (AI) - Newcastle disease (ND). - Prescribed and ... Rift Valley fever. - Bovine tuberculosis. - Bovine spongiform encephalopathy. - Classical swine fever. - Avian influenza - ...
MH DELETED MN ADDED MN
Classical swine fever virus B4.909.777.310.700.400 Clerodendrum B1.650.940.800.575.100.960.155 B1.650.940.800.575.100.583.520. ... African horse sickness virus B4.909.777.714.550.50 (Replaced for 2015 by African Horse Sickness Virus) African Swine Fever ... Rift Valley fever virus B4.909.777.147.710.700 Rinderpest virus B4.909.777.455.600.650.500.675 RING Finger Domains G2.111. ... Hemorrhagic Disease Virus, Rabbit B4.909.777.162.500.380 Hemorrhagic Fever Virus, Crimean-Congo B4.909.777.147.565.400 Hendra ...
Volume 94, Issue 8 | Microbiology Society
Analysis of classical swine fever virus RNA replication determinants using replicons Peter Christian Risager, Ulrik Fahnøe, ... derived from the genome of the Paderborn strain of classical swine fever virus (CSFV) have been produced. The full-length viral ... RNA viruses * RAGE inhibits human respiratory syncytial virus syncytium formation by interfering with F-protein function Jane ... The 2009 swine-origin pandemic H1N1 (pH1N1) influenza virus transmitted and caused disease in many individuals immune to pre- ...
PE Anti-Porcine CD1, 76-7-4 | SouthernBiotech
Classical swine fever virus suppresses maturation and modulates functions of monocyte-derived dendritic cells without ... 3. Pauly T, König M, Thiel H, Saalmüller A. Infection with classical swine fever virus: effects on phenotype and immune ... Interferon-induced protection against foot-and-mouth disease virus infection correlates with enhanced tissue-specific innate ... Thymic transplantation in miniature swine. I. Development and function of the "thymokidney". Transplantation. 1999;68:1684-92 ...
University of Surrey - Research Supported by FAPESP
... caused by the classical swine fever virus (CSFV). CSFV is an enveloped, single-stranded RNA virus that belongs to the ... Classical Swine Fever (CSF) is a contagious, hemorrhagic and often fatal disease of Suidae, such as pigs and wild boar, ... Systems immunology approach for resolving the mechanisms of vaccine-induced classical swine fever protection, AP.R SPRINT ... distantly related for example to Zika and Yellow Fever virus. CSFV can be controlled by vaccination particularly usi… ...
Controlling disease outbreaks in wildlife using limited culling: modelling classical swine fever incursions in wild pigs in...
Published data on wild pig ecology from Australia, and international Classical Swine Fever data was used to parameterise the ... exposed-infected-recovered process model that simulates the potential spread of classical swine fever through a documented, ... Classical swine fever transmission. The models treatment of virus transmission can be considered in two ways, transition of ... OIE: Classical Swine Fever: General Disease Information Sheets. Book Classical Swine Fever: General Disease Information Sheets ...
Rabbit Anti Yellow fever Virus envelope | 498-BS-2041r
Rabbit Anti Yellow fever Virus envelope Manufactured by Gentaur. Gentaur is the biggest antibody manufacturer worldwide. ... Rabbit Anti-classical Swine fever Virus , Gentaur Gentaur. MSRP: Now: TL340.00 Was: ... Rabbit Anti Yellow fever Virus envelope , Gentaur Gentaur Rabbit Anti Yellow fever Virus envelope , Gentaur. (No reviews yet) ... Rabbit Anti Yellow fever Virus envelope , Gentaur. Rating Required Select Rating. 1 star (worst). 2 stars. 3 stars (average). 4 ...
Ciencias de la Salud - Research output
- Universidad Nacional Mayor de San Marcos
The Influence of Between-Farm Distance and Farm Size on the Spread of Classical Swine Fever during the 1997-1998 Epidemic in...
Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this ... Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this ... Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this ... Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this ...
CSFVPseudorabies virusOutbreakDiseasesContagiousAntibodiesDetectionAntibodyPathogensControl and eradicationPestivirus1997-1998EndemicASFV2001GlycoproteinInfectionPigsAcutePorcine circovirusViral diarrhea virusRecombinantPRRSVaccineEpidemiologyAvianAfricanDiseaseSubunitInfectionsSerologyFarmsSowsLaboratoryDetectProteinSpreadMortalityImmunityInfectiousDiagnosisStrainsProteins
CSFV17
- CSFV, classical swine fever virus. (cdc.gov)
- Classical swine fever (CSF) is caused by classical swine fever virus (CSFV) and has lead huge losses to the pig industry worldwide. (researchsquare.com)
- In this study, humoral and cellular immune response elicited in inbred BALB/c mice by immunization with a recombinant classical swine fever virus (CSFV) E2 protein fused to porcine CD154 antigen (E2CD154) was assessed. (edu.sa)
- Therefore, this immunogen might be an appropriate candidate to elicit immune response in swine, control CSF disease and to eliminate CSFV in swine. (edu.sa)
- Two groups with three wild boars each were used: Group A (animals 1 to 3) served as the control, and Group B (animals 4 to 6) was postnatally persistently infected with the Cat01 strain of CSFV (primary virus). (illinois.edu)
- Additionally, in PBMCs, a well-known target for CSFV viral replication, only the primary infecting virus RNA (Cat01 strain) could be detected, even after the isolation in ST cells, demonstrating SIE at the tissue level in vivo. (illinois.edu)
- Finally, a sequence analysis could not detect CSFV Margarita RNA in the samples tested from Group B. Our results suggested that the SIE phenomenon might be involved in the evolution and phylogeny of the virus, as well as in CSFV control by vaccination. (illinois.edu)
- Classical swine fever virus (CSFV) is an enveloped positive-stranded RNA virus (20) of the genus Pestivirus of the Flavi-viridae family (34). (1library.net)
- The Classical Swine Fever virus (CSFV) is a major pathogen of livestock. (peerj.com)
- Classical Swine Fever (CSF) is a contagious, hemorrhagic and often fatal disease of Suidae, such as pigs and wild boar, caused by the classical swine fever virus (CSFV). (fapesp.br)
- CSFV is an enveloped, single-stranded RNA virus that belongs to the Flaviviridae family (Moennig, 2000), distantly related for example to Zika and Yellow Fever virus. (fapesp.br)
- It's laborious to diagnose the infections of classical swine fever virus (CSFV), porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus sort 2 (PCV2), and Suid herpesvirus 1 (SuHV-1) due to the same scientific signs in piglets. (computablegenomix.com)
- It has been shown in clinical cases to be a commonly mixed infection with Pseudorabies virus (PRV), classical swine fever virus (CSFV), Porcine Reproductive and Respiratory Syndrome virus (PRRSV). (biomedcentral.com)
- CSFV causes infected swine to develop a fever, excessive bleeding, lethargy, diarrhea that is yellow in color, retching, and purplish-colored skin discoloration of areas such as the ears, legs, and lower stomach. (iloveveterinary.com)
- This is due to the clinical signs manifested by CSFV-infected pigs are also common with other diseases of swine. (iloveveterinary.com)
- Classical swine fever virus (CSFV) is an enveloped positive-stranded. (city-made.com)
- Control of classical swine fever virus (CSFV) in endemic countries relies on vaccination, mostly using vaccines that do not allow for differentiation of vaccinated from infected animals (DIVA). (bvsalud.org)
Pseudorabies virus12
- Megan Niederwerder , lead researcher and Kansas State assistant professor of diagnostic medicine and pathobiology, and her colleagues have published the first report of classical swine fever virus and pseudorabies virus stability in feed ingredients subjected to different environmental conditions mimicking transpacific shipment. (thepigsite.com)
- "Stability of classical swine fever virus and pseudorabies virus in animal feed ingredients exposed to transpacific shipping conditions " is available online in the journal Transboundary and Emerging Diseases . (thepigsite.com)
- Classical swine fever virus and pseudorabies virus cause two of the top four transboundary animal diseases of importance to swine," Niederwerder said. (thepigsite.com)
- Currently, U.S. commercial swine are free of both classical swine fever virus and pseudorabies virus because of costly eradication programs completed in 1978 and 2004, respectively. (thepigsite.com)
- Recent changes in pseudorabies virus strain virulence and classical swine fever virus geographic distribution are of great concern for these trade-limiting diseases. (thepigsite.com)
- The emerging threat of classical swine fever virus and pseudorabies virus being reintroduced into U.S. commercial swine is significant and preventing entry is critical for the U.S. pork industry," Niederwerder said. (thepigsite.com)
- However, the stability of classical swine fever virus and pseudorabies virus in imported feed ingredients had yet to be investigated. (thepigsite.com)
- In the researchers' study, they found both viruses survived for the length of the 37-day model in feed, with pseudorabies virus having increased stability across a broader range of feed ingredients when compared to classical swine fever virus. (thepigsite.com)
- Niederwerder said pseudorabies virus was detected in nine of the 12 tested ingredients: conventional and organic soybean meal, lysine, choline, vitamin D, moist cat and dog food, dry dog food, and pork sausage casings at the conclusion of the simulated voyage. (thepigsite.com)
- This study reports novel data about environmental stability of classical swine fever virus and pseudorabies virus in feed and includes important quantitative information that can be incorporated into risk models for preventing the potential spread of classical swine fever virus and pseudorabies virus through imported feed ingredients," Niederwerder said. (thepigsite.com)
- Samples are also tested for pseudorabies virus and swine brucellosis. (usda.gov)
- He said in the year 2000, Uruguay's Ministry of Agriculture and the swine industry completed a serological study of pigs there, looking for antibodies of PRRS, pseudorabies virus (PRV), classical swine fever (CSF), and other diseases. (swinehealth.org)
Outbreak13
- The classical swine fever outbreak in The Netherlands during 1997 and 1998 resulted in destruction of more than 10 million pigs at a cost of more than 2 billion U.S. dollars (25). (1library.net)
- Mintiens K., Deluyker H., Laevens H., Koenen F., Dewulf J., De Kruif A., Descriptive epidemiology of a classical swine fever outbreak in the Limburg Province of Belgium in 1997, J. Vet. (vetres.org)
- The route of introducing and transmitting swine viruses through feed has been recognized since the 2013-2014 outbreak of porcine epidemic diarrhea virus. (thepigsite.com)
- Stanojevic S., Valcic M., Stanojevic S., Radojicic S., Avramov S., Tambur Z. (2015): Simulation of a classical swine fever outbreak in rural areas of the Republic of Serbia. (agriculturejournals.cz)
- Engel B, Bouma A, Stegeman A, Buist W, Elbers A, Kogut J, Dopfer D, Mart de Jong CM (2005): When can a veterinarian be expected to detect classical swine fever virus among breeding sows in a herd during an outbreak? (agriculturejournals.cz)
- Today Fort Baker is a part of the Golden Gate National Park where they have a children's museum and activities on the location of the US Army's Biological Research Field Laboratory that was closed down when an outbreak of Q Fever swept the base in 1979. (home.blog)
- More than 6,000 feral swine samples per year are collected and screened for these pathogens through this surveillance program, providing important information that helps protect domestic animals, wildlife and humans from a major zoonotic disease outbreak. (usda.gov)
- The swine industry in Colombia is just as concerned about disease outbreak and spread as the US industry," he stated. (swinehealth.org)
- Analysis and evaluation of mortality losses of the 2001 African swine fever outbreak, Ibadan, Nigeria. (waset.org)
- Emergency assistance on control and eradication of an outbreak of African swine fever in Western Nigeria. (waset.org)
- His primary scientific interests are in Outbreak, Veterinary medicine, Virology, Virus and Classical swine fever. (research.com)
- His primary areas of investigation include Veterinary medicine, Outbreak, Virology, Wild boar and Influenza A virus subtype H5N1. (research.com)
- The scientist's investigation covers issues in Wild boar, Veterinary medicine, African swine fever, Outbreak and Influenza A virus subtype H5N1. (research.com)
Diseases12
- Niederwerder said reintroduction of these viruses into U.S. swine herds would be devastating and that there are concerns that feed ingredients incorporated into swine diets may serve as new sources for the spread of animal diseases with economic and welfare significance. (thepigsite.com)
- SWINOSTICS' mobile diagnostic system is based on biosensing and photonics technologies that reliably and quickly detect swine viral diseases in minutes. (nationalhogfarmer.com)
- The swine diseases field diagnostic toolbox is crucial not only for animal and food safety but also for human health in general," says Giusti. (nationalhogfarmer.com)
- The NWDP collaborates with the National Feral Swine Damage Management Program on disease management, research, pathogen surveillance, emergency response, education and outreach regarding diseases of feral swine. (usda.gov)
- Surveillance for feral swine diseases is conducted by the National Feral Swine Damage Management Program. (usda.gov)
- Efforts primarily focus on early detection of diseases that are not currently in the US, including classical swine fever, African swine fever, and foot-and-mouth disease. (usda.gov)
- It has been shown in clinical cases to be a commonly mixed infection with other important swine diseases which can aggravate the severity of the disease and bring serious economic losses to the pig industry. (biomedcentral.com)
- The Swine Health Information Center (SHIC) has funded a near real-time global surveillance system for swine diseases. (swinehealth.org)
- The US swine industry is free of several swine diseases now being identified in different countries throughout the world. (swinehealth.org)
- Using an international network of veterinarians, academics and allied industry, SHIC has surveyed for swine diseases circulating in other countries for the last two years. (swinehealth.org)
- SHIC has also funded researchers at the University of Minnesota to develop a more formal and regular way to monitor for emerging and circulating swine diseases around the world. (swinehealth.org)
- Some new capabilities include a state-of-the-art necropsy laboratory, modern testing instruments, and specialized laboratory space to handle select agents, dangerous pathogens and highly toxic chemicals, increasing the laboratory's capacity to respond to high consequential and emerging animal diseases such as influenza viruses in birds and dogs,, foot-and-mouth-disease and classical swine fever, among others. (nj.gov)
Contagious4
- A species of the PESTIVIRUS genus causing exceedingly contagious and fatal hemorrhagic disease of swine. (bvsalud.org)
- African swine fever (ASF) is a highly contagious hemorrhagic viral disease of wild and domestic pigs, capable of killing entire herds and resulting in substantial economic and production losses globally. (usda.gov)
- Swine influenza viruses (SIV) produce a highly contagious and worldwide distributed disease that can cause important economic losses to the pig industry. (bvsalud.org)
- An acute, highly contagious disease affecting swine of all ages and caused by the CLASSICAL SWINE FEVER VIRUS . (bvsalud.org)
Antibodies7
- No cross reaction with other swine virus antibodies was observed. (researchsquare.com)
- Furthermore, these animals were unable to elicit adaptive humoral (no E2-specific or neutralising antibodies) or cellular immune responses (in terms of IFN-γ-producing cells) after inoculation with the second virus. (illinois.edu)
- The PIC's surface contains antibodies against the targeted swine viruses. (nationalhogfarmer.com)
- When a sample containing a virus is passed over the sensors, this virus binds to the antibodies. (nationalhogfarmer.com)
- A serosurveillance study was conducted to detect the presence of antibodies to African swine fever virus (ASFV) and Classical swine fever virus in pigs sampled from piggeries and Makurdi central slaughter slab in Benue State, Nigeria. (waset.org)
- Detection of African swine fever virus (ASFV) antibodies in pigs in Taraba state north east Nigeria. (waset.org)
- Seroprevalence of Classical Swine Fever Antibodies in Slaughtered Pigs at Bodija Municipal Abattoir, Ibadan, South West Nigeria. (waset.org)
Detection4
- The detection of clinical swine serum samples (n=138) demonstrated that the agreement of the new E2 test strip with three commercial ELISA kits was 88.40% (122/138), 86.23% (119/138), and 96.38% (133/138), respectively. (researchsquare.com)
- Backer J.A., Brouwer H., van Schaik G., van Roermund H.J.W. (2011): Using mortality data for early detection of Classical Swine Fever in The Netherlands. (agriculturejournals.cz)
- Taking into consideration the differences in the development of the pig industry in the two countries, in particular the difference in the rate of vaccination against PRRS, which is much higher in Germany, it seems plausible that the characteristics of the farm and overall health management greatly influence the success of PRRS virus detection in this kind of sample. (hipra.com)
- A recent study 1 suggests that meconium-stained fetuses, along with those decomposed but not autolytic, are the best samples for detection of the PRRS virus in the thymus, lungs and serum of fetuses using PCR. (hipra.com)
Antibody5
- Classical Swine Fever Virus Antibody (IgG) ELISA Kit is Available at Gentaur Genprice with the fastest delivery. (joplink.net)
- CusabioHuman anti-epidemic hemorrhagic fever virus antibody (IgG) ELISA Kit is Available at Gentaur Genprice with. (joplink.net)
- CusabioHuman Rabies Virus (RV) Antibody (IgG) ELISA Kit is Available at Gentaur Genprice with the fastest delivery.Online Order. (joplink.net)
- CusabioDog rabies virus (RV) antibody (IgG) ELISA Kit is Available at Gentaur Genprice with the fastest delivery.Online Order Payment. (joplink.net)
- Muasya D, Vanleeuwen J, Gitau G, McKenna S, Heider L, Muraya J. "Evaluation of antibody and antigen cross-reaction in Kenyan dairy cattle naturally infected with two pestiviruses: Bovine viral diarrhea virus and classical swine fever virus. (ac.ke)
Pathogens1
- The selected primers did not yield false positive or cross reactive results with other common swine pathogens, showing high specificity. (bvsalud.org)
Control and eradication1
- Several different strategies for control and eradication of classical swine fever (CSF) were compared using a Monte Carlo method-based simulation model. (agriculturejournals.cz)
Pestivirus3
- Meyers G., Saalmüller A., Büttner M., Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation, J. Virol. (vetres.org)
- Especie del género PESTIVIRUS que causa una enfermedad hemorrágica muy contagiosa y fatal en los cerdos. (bvsalud.org)
- His Classical swine fever study incorporates themes from Wild boar, Pestivirus and Vaccination. (research.com)
1997-19982
- Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this question for CSF risks. (wur.nl)
- Jalvingh Alien W, Nielen Mirjam, Maurice Huibert, Stegeman Arjan J, Elbers Armin R.W, Dijkhuizen Aalt A (1999): Spatial and stochastic simulation to evaluate the impact of events and control measures on the 1997-1998 classical swine fever epidemic in The Netherlands. (agriculturejournals.cz)
Endemic3
- Both viruses are endemic to areas of the world where feed ingredients are manufactured and imported into the United States each year. (thepigsite.com)
- Currently, this virus is endemic in farms and, although used limitedly, trivalent vaccine application is the most extended strategy to control SIV. (bvsalud.org)
- Resveratrol also significantly reduced the replication of monkeypox virus, a zoonotic virus that is endemic in Western and Central Africa and causes human mortality. (researchgate.net)
ASFV3
- African swine fever virus (ASFV) currently represents the biggest threat to the porcine industry worldwide, with high economic impact and severe animal health and welfare concerns. (bvsalud.org)
- Outbreaks have occurred in Europe and Asia since ASFV was reintroduced into the continent in 2007 and, in 2021, ASFV was detected in the Caribbean, raising alarm about the reemergence of the virus in the Americas. (bvsalud.org)
- Given the lack of vaccines against ASFV, control of the virus relies on molecular surveillance, which can be delayed due to the need for sample shipment to specialized laboratories. (bvsalud.org)
20011
- Kaden Volker, Lange Bodo (2001): Oral immunisation against classical swine fever (CSF): onset and duration of immunity. (agriculturejournals.cz)
Glycoprotein3
- Bouma A., De Smit A.J., De Kluijver E.P., Terpstra C., Moormann R.J., Efficacy and stability of a subunit vaccine based on glycoprotein E2 of classical swine fever virus, Vet. (vetres.org)
- The Unique Glycosylation at Position 986 on the E2 Glycoprotein of Classical Swine Fever Virus Is Responsible for Viral Attenuation and Protection against Lethal Challenge. (amedeo.com)
- Influenza virus infects host cells through membrane fusion, a process mediated by the low pH-induced conformational change of the viral surface glycoprotein haemagglutinin (HA). (microbiologyresearch.org)
Infection12
- Human respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infection. (microbiologyresearch.org)
- 3. Pauly T, König M, Thiel H, Saalmüller A. Infection with classical swine fever virus: effects on phenotype and immune responsiveness of porcine T lymphocytes. (southernbiotech.com)
- Interferon-induced protection against foot-and-mouth disease virus infection correlates with enhanced tissue-specific innate immune cell infiltration and interferon-stimulated gene expression. (southernbiotech.com)
- Long-term persistent infection of swine monocytes/macrophages with African swine fever virus. (waset.org)
- Risk factors for farm-level African swine fever infection in major pig-producing areas in Nigeria, 1997-2011. (waset.org)
- Abortion in the later stages of pregnancy is the clinical manifestation of PRRS virus infection that causes most concern to farmers. (hipra.com)
- Even though much research has been done, the pathogenesis of intrauterine PRRS virus infection remains largely unknown. (hipra.com)
- If the herd management and housing conditions are adequate, outbreaks of late abortions are usually attributed to an acute PRRS virus infection . (hipra.com)
- However, infection with the PRRS virus was confirmed in only 8.6% of the samples. (hipra.com)
- The selection of samples to confirm the presence of the PRRS virus in cases of abortion may also influence the outcome of the PCR , as can be deduced from the accumulated scientific evidence on the distribution of the PRRS virus in maternal and fetal tissues in cases of transplacental infection. (hipra.com)
- Meconium staining was the most consistent gross abnormality observed in fetuses infected with the PRRS virus in another study 2 , suggesting that this is a reliable indicator of intrauterine infection. (hipra.com)
- All in all, demonstration of PRRS virus infection in late-term aborted fetuses can be improved by sampling both meconium-stained and decomposed (non-autolytic) fetuses, umbilical cord and placenta on the farm. (hipra.com)
Pigs5
- Dahle J., Liess B., A review on classical swine fever infections in pigs: epizootiology, clinical disease and pathology, Comp. (vetres.org)
- Pigs or hogs are then infected with a highly virulent of one or more strains of the virus. (iloveveterinary.com)
- In subacute and chronic cases, the pigs are infected by mildly virulent strains of the virus. (iloveveterinary.com)
- Minimize visitors on your farm and do not allow persons who have had contact with animals in the last five days, especially swine in other countries to have contact with your pigs. (iloveveterinary.com)
- Good communication between veterinary authorities, veterinary practitioners, and pig farmers, together with a reliable disease reporting system, and hygiene measures protecting domestic pigs from contact with wild boar are the most effective measures to prevent the disease from spreading and causing havoc amongst herds of swine in the area. (iloveveterinary.com)
Acute1
- Clinically severe acute disease of cattle caused by noncytopathic forms of Bovine viral diarrhea virus 2 (DIARRHEA VIRUS 2, BOVINE VIRAL). (bvsalud.org)
Porcine circovirus2
- SWINOSTICS tool detects six viruses: African swine fever, PRRS, porcine parvovirus, porcine circovirus type 2, classical swine fever and swine influenza. (nationalhogfarmer.com)
- Porcine Circovirus type 2 (PCV2), and Japanese Encephalitis virus (JEV), which can aggravate the severity of the disease and bring serious economic losses to the pig industry [ 3 ]. (biomedcentral.com)
Viral diarrhea virus1
- Bovine viral diarrhea virus and Border disease virus of sheep. (1library.net)
Recombinant1
- Putative T7 promoter-derived transcript transcribed either in vitro or in vivo in BHK-21 cells infected by recombinant vaccinia virus vTF7-3 containing pXLCSFV130-423. (iresite.org)
PRRS2
- Now in Uruguay they are investigating where the PRRS virus came from using sequencing to characterize the genome. (swinehealth.org)
- Although this is the standard procedure for PRRS virus identification in clinical material coming from abortion, a high proportion of PCR-negative results are the most common outcome from the diagnostic laboratory, as was reported in a large-scale study in Germany. (hipra.com)
Vaccine1
- ABSTRACT Understanding the genetic evolution of A(H1N1)pdm09 and H3N2 viruses can help better select strains to be included in the annual influenza vaccine. (who.int)
Epidemiology4
- His Epidemiology research is multidisciplinary, incorporating elements of Zoology and Highly Pathogenic Avian Influenza Virus. (research.com)
- Epidemiology of classical swine fever in Germany in the 1990s. (research.com)
- His study in the field of Virus and Vaccination also crosses realms of Molecular epidemiology and Western europe. (research.com)
- His studies in African swine fever integrate themes in fields like Surveillance data, Epidemiological surveillance, Epidemiology and Seroprevalence. (research.com)
Avian1
- His work on Highly Pathogenic Avian Influenza Virus as part of general Virus research is frequently linked to Reassortment, bridging the gap between disciplines. (research.com)
African12
- African Swine Fever, Vesicular Stomatitis Virus, Classical Swine Fever and Foot-and-Mouth Disease Virus. (usda.gov)
- This information adds to our work on African swine fever and reinforces the concept of feed biosecurity for disease prevention. (thepigsite.com)
- African swine fever was eradicated in Malta by killing every pig in the country. (uia.org)
- ASF or African Swine Fever is the headlining differential because it has a similar clinical manifestation. (iloveveterinary.com)
- 4] Awosanya E. J., Olugasa B., Ogundipe G and Grohn Y. P. (2015): Seroprevalence and risk factors associated with African swine fever on pig farms in southwest Nigeria. (waset.org)
- African swine fever: how can global spread be prevented? (waset.org)
- Surveillance of African swine fever in Nigeria, 2006-2009. (waset.org)
- Field surveillance and laboratory diagnoses of African swine fever in Nigeria (IAEA-CN-174-151). (waset.org)
- He interconnects Classical swine fever, African swine fever, Epidemiological surveillance and Pseudorabies in the investigation of issues within Wild boar. (research.com)
- African Swine Fever: Fast and Furious or Slow and Steady? (research.com)
- Analysis of Estonian surveillance in wild boar suggests a decline in the incidence of African swine fever. (research.com)
- Christoph Staubach mostly deals with Wild boar, African swine fever, Disease, Serology and Goose. (research.com)
Disease8
- The 2009 swine-origin pandemic H1N1 (pH1N1) influenza virus transmitted and caused disease in many individuals immune to pre-2009 H1N1 influenza virus. (microbiologyresearch.org)
- Classical swine fever has occurred in Australia, where it is considered an exotic disease, four times, the last in 1961. (uia.org)
- The Army called it an accident as they were experimenting on Sheep and goats that just so happen to have Q Fever, and the disease infected the base. (home.blog)
- During Desert Storm the Army claimed that the disease Q Fever had infected its soldiers in the field and that this was the first time it was seen by the military. (home.blog)
- They can be reservoirs of disease and may act as a host to a number of parasites, leaving the United States domestic swine industry vulnerable to disease. (usda.gov)
- The Swine Health Information Center (SHIC) mission includes global disease monitoring. (swinehealth.org)
- His Goose research includes elements of Severe disease, Influenza A virus subtype H5N1 and Virology. (research.com)
- Caprine Arthritis-Encephalitis Virus (CAEV) is an incurable disease of goats that has both social and economic impacts. (bepress.com)
Subunit1
- The development of subunit vaccines against classical swine fever is a desirable goal, because it allows discrimination between vaccinated and infected animals. (edu.sa)
Infections1
- There are variants of those viruses that might cause infections that aren't obvious but still there. (swinehealth.org)
Serology1
- The diagnosis of the classical swine fever virus is based on factors such as clinical signs, serology, virus isolation, and PCR. (iloveveterinary.com)
Farms3
- These all cause epidemics in swine farms throughout Europe. (nationalhogfarmer.com)
- It also has a direct positive economic impact on swine farms and the agri-food sector. (nationalhogfarmer.com)
- The butchering of all swine on affected farms, commercial or otherwise. (iloveveterinary.com)
Sows1
- In gravid sows, the virus can infect the piglets through the placenta. (iloveveterinary.com)
Laboratory2
- Anonymous (2002): Commission Decision of 1 February 2002 approving a Diagnostic Manual establishing diagnostic procedure, sampling methods and criteria for evaluation of the laboratory tests for the confirmation of classical swine fever. (agriculturejournals.cz)
- In these cases the sample used to confirm the presence of the virus in the laboratory is the aborted material, usually accomplished by the polymerase chain reaction assay (PCR). (hipra.com)
Detect2
- Moreover, it is compatible with sensors designed to detect any type of virus. (nationalhogfarmer.com)
- Although aborted material is sent to the lab in an attempt to detect the virus, the result is often frustrating. (hipra.com)
Protein2
- RAGE appeared to interact directly with the F protein, but, rather than inhibiting RSV entry into host cells, virus replication and budding, membrane-expressed RAGE or soluble RAGE blocked F-protein-mediated syncytium formation and sloughing. (microbiologyresearch.org)
- The first section of this review describes types of viral fusion proteins and is followed by a comparison of the structural features of class I fusion proteins, namely influenza virus hemagglutinin and the S-protein of the human coronavirus. (bvsalud.org)
Spread6
- What's the risk for spread of classical swine fever and pseudorabies through feed? (thepigsite.com)
- Epstein-Barr virus (EBV) is a wide-spread human herpesvirus that is highly associated with infectious mononucleosis and several malignancies. (biomedcentral.com)
- This paper describes a spatio-temporal, stochastic, susceptible- exposed-infected-recovered process model that simulates the potential spread of classical swine fever through a documented, large and free living wild pig population following a simulated incursion. (biomedcentral.com)
- Because clinical symptoms are not severe, outbreaks caused by low virulent strains may pass unnoticed for weeks or months, thus giving rise to a considerable spread of the virus. (uia.org)
- Swine fever is widely spread throughout the tropical countries of Latin America and Southeast Asia. (uia.org)
- rarely, it happens that the virus is spread by aerosol in close confinement or by vectors. (iloveveterinary.com)
Mortality1
- Swine fever, having a high mortality rate, can cause severe economic losses among livestock. (uia.org)
Immunity3
- König M., Lengsfeld T., Pauly T., Stark R., Thiel H.J., Classical swine fever virus: independent induction of protective immunity by two structural glycoproteins, J. Virol. (vetres.org)
- These studies highlight the importance of vaccinating against immunodominant T-cell epitopes to provide for a more effective strategy to control influenza virus through heterosubtypic immunity. (microbiologyresearch.org)
- The presence of pre-existing immunity against SIV may modulate the evolutionary dynamic of this virus. (bvsalud.org)
Infectious2
- When looking at classical swine fever virus, two of the 12 ingredients had infectious virus detected: conventional soybean meal and pork sausage casings. (thepigsite.com)
- Bovine Rhinotracheitis Virus - The infectious bovine rhinotracheitis (IBR) virus belongs to the group of herpes viruses. (home.blog)
Diagnosis1
- Differential diagnosis of a swine epizootic of unknown aetiology in Ibadan, Oyo State, Nigeria. (waset.org)
Strains1
- The results show that despite homology shared between pre-2009 H1N1 and pH1N1 strains, the effector memory T-cell response to pre-2009 H1N1 was generally ineffective, a finding that correlated with lung virus persistence. (microbiologyresearch.org)
Proteins3
- Armengol E., Wiesmüller K.-H., Wienhold D., Büttner M., Pfaff E., Jung G., Saalmüller A., Identification of T-cell epitopes in the structural and non-structural proteins of classical swine fever virus, J. Gen. Virol. (vetres.org)
- The underlying mechanisms allowing West Nile virus (WNV) to replicate in a large variety of different arthropod, bird and mammal species are largely unknown but are believed to rely on highly conserved proteins relevant for viral entry and replication. (microbiologyresearch.org)
- A number of enveloped viruses confer fusion of the viral envelope and the cell membrane using surface viral fusion proteins. (bvsalud.org)