Classical swine fever virus: A species of the PESTIVIRUS genus causing exceedingly contagious and fatal hemorrhagic disease of swine.Classical Swine Fever: An acute, highly contagious disease affecting swine of all ages and caused by the CLASSICAL SWINE FEVER VIRUS. It has a sudden onset with high morbidity and mortality.African Swine Fever Virus: The lone species of the genus Asfivirus. It infects domestic and wild pigs, warthogs, and bushpigs. Disease is endemic in domestic swine in many African countries and Sardinia. Soft ticks of the genus Ornithodoros are also infected and act as vectors.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).African Swine Fever: A sometimes fatal ASFIVIRUS infection of pigs, characterized by fever, cough, diarrhea, hemorrhagic lymph nodes, and edema of the gallbladder. It is transmitted between domestic swine by direct contact, ingestion of infected meat, or fomites, or mechanically by biting flies or soft ticks (genus Ornithodoros).Pestivirus: A genus of FLAVIVIRIDAE, also known as mucosal disease virus group, which is not arthropod-borne. Transmission is by direct and indirect contact, and by transplacental and congenital transmission. Species include BORDER DISEASE VIRUS, bovine viral diarrhea virus (DIARRHEA VIRUS, BOVINE VIRAL), and CLASSICAL SWINE FEVER VIRUS.Border disease virus: A species of PESTIVIRUS causing a congenital sheep disease characterized by an abnormally hairy birth-coat, tremors, and poor growth.Iridoviridae: A family of large icosahedral DNA viruses infecting insects and poikilothermic vertebrates. Genera include IRIDOVIRUS; RANAVIRUS; Chloriridovirus; Megalocytivirus; and Lymphocystivirus.Pestivirus Infections: Infections with viruses of the genus PESTIVIRUS, family FLAVIVIRIDAE.Yellow fever virus: The type species of the FLAVIVIRUS genus. Principal vector transmission to humans is by AEDES spp. mosquitoes.RNA, Viral: Ribonucleic acid that makes up the genetic material of viruses.Viral Vaccines: Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.Rift Valley fever virus: A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.Diarrhea Viruses, Bovine Viral: A group of viruses in the genus PESTIVIRUS, causing diarrhea, fever, oral ulcerations, hemorrhagic syndrome, and various necrotic lesions among cattle and other domestic animals. The two species (genotypes), BVDV-1 and BVDV-2 , exhibit antigenic and pathological differences. The historical designation, BVDV, consisted of both (then unrecognized) genotypes.Viral Envelope Proteins: Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.Sus scrofa: A species of SWINE, in the family Suidae, comprising a number of subspecies including the domestic pig Sus scrofa domestica.Virulence: The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.Palatine Tonsil: A round-to-oval mass of lymphoid tissue embedded in the lateral wall of the PHARYNX. There is one on each side of the oropharynx in the fauces between the anterior and posterior pillars of the SOFT PALATE.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Viral Nonstructural Proteins: Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.Viral Proteins: Proteins found in any species of virus.Viral Structural Proteins: Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). These do not include the proteins encoded in the VIRAL GENOME that are produced in infected cells but which are not packaged in the mature virus particle,i.e. the so called non-structural proteins (VIRAL NONSTRUCTURAL PROTEINS).Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Swine Diseases: Diseases of domestic swine and of the wild boar of the genus Sus.Antibodies, Viral: Immunoglobulins produced in response to VIRAL ANTIGENS.Vero Cells: A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.Virus Replication: The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.Cytopathogenic Effect, Viral: Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysosomal enzymes, changes in cell membrane permeability, diffuse changes in intracellular structures, presence of viral inclusion bodies, and chromosomal aberrations. It excludes malignant transformation, which is CELL TRANSFORMATION, VIRAL. Viral cytopathogenic effects provide a valuable method for identifying and classifying the infecting viruses.Antigens, Viral: Substances elaborated by viruses that have antigenic activity.Hemorrhagic Fever Virus, Crimean-Congo: A species of NAIROVIRUS of the family BUNYAVIRIDAE. It is primarily transmitted by ticks and causes a severe, often fatal disease in humans.Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.Antibodies, Neutralizing: Antibodies that reduce or abolish some biological activity of a soluble antigen or infectious agent, usually a virus.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Cercopithecus aethiops: A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.Viremia: The presence of viruses in the blood.Genome, Viral: The complete genetic complement contained in a DNA or RNA molecule in a virus.Yellow Fever: An acute infectious disease primarily of the tropics, caused by a virus and transmitted to man by mosquitoes of the genera Aedes and Haemagogus. The severe form is characterized by fever, HEMOLYTIC JAUNDICE, and renal damage.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Vaccines, Attenuated: Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity.Host-Pathogen Interactions: The interactions between a host and a pathogen, usually resulting in disease.Rift Valley Fever: An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.Ornithodoros: A genus of softbacked TICKS, in the family ARGASIDAE, serving as the vector of BORRELIA, causing RELAPSING FEVER, and of the AFRICAN SWINE FEVER VIRUS.Endopeptidases: A subclass of PEPTIDE HYDROLASES that catalyze the internal cleavage of PEPTIDES or PROTEINS.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Asfarviridae: A family of double-stranded DNA viruses containing one genus Asfivirus. It is the source of AFRICAN SWINE FEVER.Animals, Wild: Animals considered to be wild or feral or not adapted for domestic use. It does not include wild animals in zoos for which ANIMALS, ZOO is available.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Umbilical Veins: Venous vessels in the umbilical cord. They carry oxygenated, nutrient-rich blood from the mother to the FETUS via the PLACENTA. In humans, there is normally one umbilical vein.Qi: The vital life force in the body, supposedly able to be regulated by acupuncture. It corresponds roughly to the Greek pneuma, the Latin spiritus, and the ancient Indian prana. The concept of life-breath or vital energy was formulated as an indication of the awareness of man, originally directed externally toward nature or society but later turned inward to the self or life within. (From Comparison between Concepts of Life-Breath in East and West, 15th International Symposium on the Comparative History of Medicine - East and West, August 26-September 3, 1990, Shizuoka, Japan, pp. ix-x)Electrodes: Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.Electrochemistry: The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.2,2'-Dipyridyl: A reagent used for the determination of iron.Solar Energy: Energy transmitted from the sun in the form of electromagnetic radiation.Electrochemical Techniques: The utilization of an electrical current to measure, analyze, or alter chemicals or chemical reactions in solution, cells, or tissues.Luminescent Measurements: Techniques used for determining the values of photometric parameters of light resulting from LUMINESCENCE.Ruthenium: A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.

Localization of pestiviral envelope proteins E(rns) and E2 at the cell surface and on isolated particles. (1/236)

The glycoproteins E(rns) of classical swine fever virus (CSFV) and E(rns) and E2 of bovine viral diarrhoea virus (BVDV) are shown to be located at the surface of infected cells by the use of indirect immunofluorescence and by cytofluorometric analysis. The positive immunostaining of the cell surface was further analysed by immunogold electron microscopy and it could be shown that only extracellular virions were labelled. Gold granules were not seen at the cellular plasma membrane. In contrast to BVDV E2, the CSFV E2 of virions sticking to the plasma membrane was not accessible to the respective monoclonal antibodies. However, CSFV particles isolated from culture supernatant were able to bind both monoclonal anti-E(rns) and anti-E2 antibodies. For CSFV and BVDV, binding of anti-E(rns) antibodies to the virions was more pronounced than that of anti-E2. This finding was unexpected since E2 is considered to be the immunodominant glycoprotein.  (+info)

Cytopathogenic and noncytopathogenic RNA replicons of classical swine fever virus. (2/236)

To determine the minimal requirements for autonomous RNA replication of classical swine fever virus (CSFV), genomes having in-frame deletions within the genes for structural and flanking nonstructural proteins were constructed, based on an infectious cDNA clone of CSFV Alfort/187. RNA was transcribed in vitro from the respective plasmids and transfected into SK-6 swine kidney cells. The replication competence of the RNA was determined by immunostaining transfected cells for CSFV NS3 protein and by analysis of cell extracts for viral RNA, as well as protein synthesis at different times after transfection. The genes encoding N(pro), C, E(rns), E1, E2, p7, and NS2 proved to be dispensable for RNA replication, but the efficiency of replication varied strongly between individual constructs. RNA replicons containing the complete NS2-NS3 gene persisted in transfected cells and continued to replicate without causing any obvious morphological or functional damage to the cells, whereas genomes lacking the NS2 gene replicated more efficiently and induced a cytopathic effect. These findings suggest that NS2, although it is not essential for pestivirus RNA replication, has a regulatory function therein. Both cytopathogenic and noncytopathogenic replicons were packaged into virus particles provided in trans by a cotransfected full-length helper virus genome.  (+info)

Classical swine fever in Sardinia: epidemiology of recent outbreaks. (3/236)

A variable region of the gene encoding the major glycoprotein (E2) of Classical Swine Fever Virus (CSFV) was sequenced from 12 Sardinian isolates which had been obtained from three geographically distinct regions of the Island. Phylogenetic analysis of these viruses and others characterized in previous studies [1, 2] indicated that (a) the Sardinian viruses were all members of the common European subgroup 2.3 and were clearly distinct from live vaccines recently used in this area; (b) they could be resolved into four distinct groups in accordance with the region or date of isolation; (c) in at least two regions wild boar/domestic swine contact was implicated in virus spread; (d) the oldest isolate (1983) and some of the recent isolates were possibly introduced from mainland Italy. In addition, this study has wider implications for the interpretation of CSFV variation. We have been able to demonstrate that small variations within this region of the virus genome (possibly less than 2.7% or five nucleotide substitutions) can be used to separate isolates into groups that precisely fit their geographical distribution. This finding is especially important for deducing the epidemiological relationships between multiple outbreaks caused by similar viruses that occur in close proximity.  (+info)

Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation. (4/236)

Classical swine fever (CSF) is a severe hemorrhagic disease of swine caused by the pestivirus CSF virus (CSFV). Amino acid exchanges or deletions introduced by site-directed mutagenesis into the putative active site of the RNase residing in the glycoprotein E(rns) of CSFV abolished the enzymatic activity of this protein, as demonstrated with an RNase test suitable for detection of the enzymatic activity in crude cell extracts. Incorporation of the altered sequences into an infectious CSFV clone resulted in recovery of viable viruses upon RNA transfection, except for a variant displaying a deletion of the histidine codon at position 297 of the long open reading frame. These RNase-negative virus mutants displayed growth characteristics in tissue culture that were undistinguishable from wild-type virus and were stable for at least seven passages. In contrast to animals inoculated with an RNase-positive control virus, infection of piglets with an RNase-negative mutant containing a deletion of the histidine codon 346 of the open reading frame did not lead to CSF. Neither fever nor extended viremia could be detected. Animals infected with this mutant did not show decrease of peripheral B cells, a characteristic feature of CSF in swine. Animal experiments with four other mutants with either exchanges of codons 297 or 346 or double exchanges of both codons 297 and 346 showed that all these RNase-negative mutants were attenuated. All viruses with mutations affecting codon 346 were completely apathogenic, whereas those containing only changes of codon 297 consistently induced clinical symptoms for several days, followed by sudden recovery. Analyses of reisolated viruses gave no indication for the presence of revertants in the infected animals.  (+info)

The RNA-dependent RNA polymerases of different members of the family Flaviviridae exhibit similar properties in vitro. (5/236)

The virus-encoded RNA-dependent RNA polymerase (RdRp), which is required for replication of the positive-strand RNA genome, is a key enzyme of members of the virus family Flaviviridae. By using heterologously expressed proteins, we demonstrate that the 77 kDa NS5B protein of two pestiviruses, bovine viral diarrhoea virus and classical swine fever virus, and the 100 kDa NS5 protein of the West Nile flavivirus possess RdRp activity in vitro. As originally shown for the RdRp of hepatitis C virus, RNA synthesis catalysed by the pestivirus and flavivirus enzymes is strictly primer-dependent in vitro. Accordingly, initiation of RNA polymerization on homopolymeric RNAs and heteropolymeric templates, the latter with a blocked 3'-hydroxyl group, was found to be dependent on the presence of complementary oligonucleotide primer molecules. On unblocked heteropolymeric templates, including authentic viral RNAs, the RdRps were shown to initiate RNA synthesis via intramolecular priming at the 3'-hydroxyl group of the template and 'copy-back' transcription, thus yielding RNase-resistant hairpin molecules. Taken together, the RdRps of different members of the Flaviviridae were demonstrated to exhibit a common reactivity profile in vitro, typical of nucleic acid-polymerizing enzymes.  (+info)

Classical swine fever virus E(rns) deletion mutants: trans-complementation and potential use as nontransmissible, modified, live-attenuated marker vaccines. (6/236)

An SK6 cell line (SK6c26) which constitutively expressed the glycoprotein E(rns) of classical swine fever virus (CSFV) was used to rescue CSFV E(rns) deletion mutants based on the infectious copy of CSFV strain C. The biochemical properties of E(rns) from this cell line were indistinguishable from those of CSFV E(rns). Two E(rns) deletion mutants were constructed, virus Flc23 and virus Flc22. Virus Flc23 encoded only the utmost N- and C-terminal amino acids of E(rns) (deletion of 215 amino acids) to retain the original protease cleavage sites. Virus Flc22 is not recognized by a panel of E(rns) antibodies, due to a deletion of 66 amino acids in E(rns). The E(rns) deletion mutants Flc22 and Flc23 could be rescued in vitro only on the complementing SK6c26 cells. These rescued viruses could infect and replicate in SK6 cells but did not yield infectious virus. Virus neutralization by E(rns)-specific antibodies was similar for the wild-type virus and the recombinant viruses, indicating that E(rns) from SK6c26 cells was incorporated in the viral particles. Pigs vaccinated with Flc22 or Flc23 were protected against a challenge with a lethal dose of CSFV strain Brescia. This is the first demonstration of trans-complementation of defective pestivirus RNA with a pestiviral structural protein and opens new ways to develop nontransmissible modified live pestivirus vaccines. In addition, the absence of (the antigenic part of) E(rns) in the recombinant viral particles can be used to differentiate between infected and vaccinated animals.  (+info)

Pathogenesis of granulocytopenia and bone marrow atrophy during classical swine fever involves apoptosis and necrosis of uninfected cells. (7/236)

Granulocytopenia, a hematological hallmark of classical swine fever, is partially responsible for the suppression of innate immune defenses during classical swine fever. The present report demonstrates that this depletion was apparent as early as 3 days postinfection (p.i.). Both mature peripheral and bone marrow neutrophils were affected, whereas immature neutrophils increased absolutely in the periphery and coincidentally immature myeloid progenitors in the bone marrow. These data suggest that a pathogenic relationship exists between these compartments. The central event was not the arrest of hematopoietic cell proliferation or of the mobilization process, but instead apoptosis and possibly also necrosis were shown to play a role. This increase in apoptotic and dead cells was detected as early as 1-3 days p.i. In contrast, viral RNA in bone marrow hematopoietic cells (BMHC) was first detected 5 days p.i., and significant amounts of infected BMHC were detected only 7 days p.i., with the major target being the myeloid compartment. The increased caspase-3 activity observed supported a role for apoptotic cell death. Furthermore, the elevated caspase-9 activity indicated the involvement of the mitochondrial apoptotic pathway. Taken together, the results demonstrate that granulocytopenia and bone marrow atrophy are mediated by hematopoietic cell death and that indirect virus-host-mediated mechanisms are likely to be responsible.  (+info)

Ultrastructural glomerular changes in experimental infection with the classical swine fever virus. (8/236)

Ultrastructural studies of glomerular changes were performed on 16 pigs experimentally infected with a highly virulent strain of the classical swine fever virus. Our observations revealed the thickening of glomerular basement membranes, swelling of endothelial cells and cytoplasmic vacuolization within podocytes containing abundant viral particles. An early viral infection of podocytes was suggested as the cause of selective swelling of the foot processes of these cells with the consequent obliteration of the glomerular urinary spaces. To our knowledge this is the first report of ultrastructural evidence of classical swine fever virions infecting glomerular podocytes.  (+info)

Read "Induction of immune responses in mice and pigs by oral administration of classical swine fever virus E2 protein expressed in rice calli, Archives of Virology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Read "Pathway analysis in blood cells of pigs infected with classical swine fever virus: comparison of pigs that develop a chronic form of infection or recover, Archives of Virology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Classical swine fever (CSF) is a highly contagious swine disease caused by classical swine fever virus (CSFV). Previously, we demonstrated that rAdV-SFV-E2, an adenovirus-delivered, Semliki Forest virus replicon-vectored marker vaccine against CSF, is able to protect pigs against lethal CSFV challenge. From an economical point of view, it will be beneficial to reduce the minimum effective dose of the vaccine. This study was designed to test the adjuvant effects of Salmonella enteritidis-derived bacterial ghosts (BG) to enhance the protective immunity of rAdV-SFV-E2 in pigs. Groups of 5-week-old pigs (n = 4) were immunized intramuscularly twice with 105 median tissue culture infective doses (TCID50) rAdV-SFV-E2 combined with 1010 colony forming units (CFU) BG, 106 or 105 TCID50 rAdV-SFV-E2 alone or 1010 CFU BG alone at an interval of 3 weeks, and challenged with the highly virulent CSFV Shimen strain at 1 week post-booster immunization. The results show that the pigs inoculated with 105 TCID50 rAdV-SFV
The early identification of classical swine fever epizootics is hampered by difficulties in recognising early signs of infection, due to a lack of specific clinical signs. In addition many textbook descriptions of CSF are based on observations of disease caused by historic, mainly genotype 1, strains. Our objective was to improve our knowledge of the diverse range of signs that different CSFV strains can cause by characterising the experimental infection of domestic pigs with both a recent strain of CSFV and a divergent strain. Conventional pigs were inoculated with a genotype 2.1 isolate, that caused an outbreak in the UK in 2000, and a genotype 3.3 strain that is genetically divergent from European strains. This latter strain is also antigenically distinct as it is only poorly recognised by the CSFV-specific monoclonal antibody, WH303. Transmission was monitored by use of in-contact animals. Clinical, virological and haematological parameters were observed and an extended macro- and ...
A surveillance program directed specifically at detecting Classical Swine Fever is now in progress at Iowa State University Veterinary Diagnostic Laboratory (ISU VDL). The ISU VDL is one of the 12 core laboratories in the National Animal Health Laboratory Network (NAHLN). The primary function of NAHLN labs is to participate in ongoing surveillance and response to foreign animal diseases and other events requiring an integrated laboratory effort of preparedness, controlled testing, and timely reporting. Federal funding for this program provides equipment and diagnostic reagents as well as support for technical positions and proficiency training of technicians. The ISU VDL has the in-house capability to test for Classical Swine Fever, High Pathogenic Avian Influenza and Exotic Newcastle Disease.. Diagnosticians at the ISU VDL will select suspect cases from routine submissions to the ISU VDL. The criteria listed below will be used in case selection.. ...
inproceedings{377967, author = {Dewulf, Jeroen and Laevens, Hans and KOENEN, F and Mintiens, Koen and de Kruif, Aart}, booktitle = {of the OIE International Conference on the Control of Infectious Animal Diseases by Vaccination}, title = {The use of conventional and marker vaccines in the control of classical swine fever epidemics}, year = {2004 ...
Outbreaks of classical swine fever (CSF) can lead to large economic losses and have a major impact on animal welfare. A pig infected by CSF virus (CSFV) may show specific clinical symptoms (conjunctivitis, skin haemorrhages, cyanotic ears and lameness), but often the signs are aspecific (fever, dullness, diarrhoea and loss of appetite; Klinkenberg et al. 2005). Meanwhile, the infection can spread rapidly to other pigs (Laevens et al. 1998) and to other farms. At the moment the disease is first detected, a large number of farms may already be infected. To halt the epidemic, reducing the number of susceptible animals in the affected area is often required, especially in pig-dense regions. Two methods to achieve this are pre-emptive culling and emergency vaccination. Pre-emptive culling was used in the later stages of the 1997/1998 epidemic of CSF in The Netherlands, causing a large number of animals to be destroyed or prematurely slaughtered. This and subsequent experiences with foot-and-mouth ...
Zdravilo Porcilis Pesti so preučevali v okviru dveh terenskih študij varnosti, eni na pitancih in eni na svinjah, pri čemer sta bila uporabljena različna odmerka cepiva. Terenske študije potrjujejo rezultate laboratorijskih preizkusov varnosti in kažejo, da je izdelek varen za ciljne živali (pujski od 5 meseca dalje) in najobčutljivejšo kategorijo živali (breje svinje).. Glavno merilo učinkovitosti pri terenskih študijah s pujski je bilo preživetje pujskov, če so bili izpostavljeni virusu KPK pozneje v življenju. Pujski so bili testirani tudi za viremijo (prisotnost virusa v krvi). Začetek in trajanje imunosti so merili na podlagi protiteles proti antigenu (E2) virusa KPK, ki so jih tvorili pujski. Maternalno pridobljena protitelesa niso vplivala na rezultate cepljenja.. ...
Classical Swine Fever (CSF) is an endemic disease in Cuba, and an eradication strategy by zones is planned by the Official Veterinary Service. The aim of this study was to identify high-risk areas of CSF and the risk factors associated with the disease occurrence in the Pinar del Río province, one of the prioritized areas in the eradication strategy. The outbreak occurrence at district level was analyzed through a 7-year period (2009 to 2015). A high-risk cluster (RR = 5.13, 95% CI 3.49-7.56) was detected during the last 2 years of the study period in the eastern half of the province, with 38 out of 97 districts included. The rate of CSF-affected holdings had a significant increase during 2014-2015 and seems to have occurred mainly in the high-risk cluster area. Swine population density by district (heads/km2) and road length (km) by district were associated with the disease outbreak occurrence. These results provide new insights into the knowledge of the epidemiology of the disease in Cuban endemic
Older research outputs will score higher simply because theyve had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 110,632 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries ...
Accepted name: pestivirus NS3 polyprotein peptidase. Reaction: Leu is conserved at position P1 for all four cleavage sites. Alanine is found at position P1 of the NS4A-NS4B cleavage site, whereas serine is found at position P1 of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites. Other name(s): border disease virus NS3 endopeptidase; BDV NS3 endopeptidase; bovine viral diarrhea virus NS3 endopeptidase; BVDV NS3 endopeptidase; classical swine fever virus NS3 endopeptidase; CSFV NS3 endopeptidase; p80. Comments: The polyprotein of noncytopathogenic pestiviruses is cleaved co- and post-translationally into at least 11 proteins (Npro, C, Erns, E1, E2, p7, NS2-3, NS4A, NS4B, NS5A, and NS5B) [2]. The genomes of cytopathogenic pestivirus strains express at least one additional protein, called NS3 (p80) [2]. This enzyme, which resides in the N-terminal region of NS3 (nonstructural protein 3), is essential for generation of its own C-terminus and for processing of the downstream cleavage sites, ...
2008) Classical swine fever virus vaccine stability in Lao PDR. In: Conlan, J., Blacksell, S., Morrissy, C. and Colling, A., (eds.) Management of classical swine fever and foot-and-mouth disease in Lao PDR : proceedings of an international workshop held in Vientiane, Lao PDR, 20-21 November 2006. ACIAR Proceedings No. 128. ACIAR, Canberra, Australia, pp. 80-83. Morrissy, C., Wright, L., Conlan, J., Goff, W., Colling, A., Hammond, J., Johnson, M., Blacksell, S. and Daniels, P. ...
hybridization patterns, the distinct genotypes of CSFV Brecent years. It can detect different pathogens in a could be differentiated. The results showed that the piece of chip and can differentiate the various CSFV amplified by primer CP5.6 could be classified into genotypes in the same species. In 2003, a bio-chip three genotypes, including the native, invaded, and diagnosis system was established by using classical lapinized hog cholera vaccine virus by hybridization swine fever virus (CSFV) as a model. Nucleotide with oligonucleotide probe. No cross reaction was sequences of classical swine fever virus were collected found when the bio-chip was hybridized with bovine from the GenBank, and the domestic CSFV field strains diarrhea disease virus which was closely related to the were sequenced. These sequence data were analyzed with a computer software by sequence alignment and apair of universal primers, which could amplify different News source: National Veterinary Research Insti- ...
Baroness Hayman today attended a meeting between senior MAFF officials and representatives of all industries affected by the CSF outbreak. The Minister of State had been invited to the meeting at Harleston, Norfolk, which provided a further opportunity to discuss face-to-face with those affected the practical welfare and financial problems being experienced in infected areas. Speaking after the meeting Baroness Hayman said: Classical swine fever is a highly contagious pig disease which can have a devastating impact on businesses and families, whether through the disease itself or consequential movement restrictions. I have come to East Anglia again today to listen directly to those affected by this outbreak. A variety of issues were raised which will be considered both at the control centre in Bury St Edmunds and in London. Controlling this disease remains of paramount importance to farmers and the wider industry. It is our first priority. We have been aware for some time of the potential welfare
No diagnostic sample submission is complete without including the tonsil. Because of their location in the oropharynx, the tonsils are exposed to a variety of viral and bacterial pathogens. Advances in diagnostic capabilities have made analysis of the tonsils an increasingly important tool in diagnosing a number of endemic swine diseases. United States Department of Agriculture (USDA) Animal and Plant Health Inspection Services (APHIS) now has funding to use the tonsil as part of a routine surveillance program to detect classical swine fever (CSF) and is offering incentives to encourage practitioners to submit samples for surveillance.. Tests using the tonsil have been developed by the Foreign Animal Disease Diagnostic Laboratory (FADDL) at USDAs Plum Island Animal Disease Center to aid in detection and diagnosis of CSF. USDAs Classical Swine Fever (CSF) Surveillance Procedure Manual1 includes tonsil, tonsil scrapings, and nasal swabs as appropriate samples for CSF detection if collected and ...
This video covers vaccines and diagnostic tests for avian influenza and is designed for those who will select vaccines and diagnostic tests to be used in an H5N1 avian influenza control program ...
TY - ABST. T1 - Virulence in pigs of vPader10 rescued from an infectious cDNA clone of the CSFV strain Paderborn. AU - Friis,Martin Barfred. AU - Nielsen,Jens. AU - Uttenthal,Åse. AU - Belsham,Graham. AU - Rasmussen,Thomas Bruun. PY - 2012. Y1 - 2012. N2 - The BAC clone, pBeloPader10, contains a complete cDNA of the CSFV strain Paderborn. Virus, named vPader10, was rescued from this construct by electroporation of RNA transcripts into porcine PK15 cells. To further study the characteristics of vPader10, we evaluated the virulence of this virus in vivo in pigs. An animal experiment was performed where three pigs were inoculated with vPader10 and housed in-contact with two non-inoculated pigs for 5 weeks. Following inoculation with vPader10, two out of three pigs displayed severe clinical signs of CSF from PID 14 that progressed until death of the pigs at PID 21 and PID 22, respectively. High fever (,41ºC) was observed in these pigs from PID 14 and remained at a high level until day of death. ...
Classical swine fever is currently not only a problem in certain regions of Germany but also in the Eastern Cape region. An outbreak means severe economical problems. The Eastern Cape agriculture authorities even admitted that they don`t know whether they are winning the fight against swine fever.
5 September 2000 New case of swine fever in Suffolk By FWi staff A FURTHER case of classical swine fever has been confirmed on a farm in the surveillance a
The domestic swine fever virus C strain was purified by USA, Japan, local swine fever, but the domestic swine fever epidemic is still serious. Control of classical swine fever, the industry has different views, many people think is the prob
Economics of classical swine fever - CSF - hog cholera - movement ban controls on UK pig farms in protection and surveillance zones.
MAFF staff are working all out to tackle the outbreak of Classical Swine Fever in East Anglia and lift the movement restrictions affecting farmers. Chief Veterinary Officer Jim Scudamore today told pig industry representatives he understood how important it was for farmers in restricted areas to be able to look forward and plan for the lifting of restrictions but that work on controlling the disease must come first. Mr Scudamore told a meeting of stakeholders in London: It is a huge task and we must prioritise. We have already had help from official vets from Northern Ireland and the Republic of Ireland, and private vets from the Netherlands. We are seeking additional specialist help from American and Dutch veterinary services and we are recruiting additional non-veterinary support staff locally. We have developed plans for carrying out all the inspections, examinations and sampling which will be required before the Infected Area restrictions can be lifted. However, these will need to be revised in
Gómez-Villamandos, JC, Carrasco, L, Bautista, MJ, Sierra, MA, Quezada, M, Hervas, J, Chacón, MDEL, Ruiz-Villamor, E, Salguero, FJ, Sónchez-Cordón, PJ, Romanini, S, Núñez, A, Mekonen, T, Méndez, A and Jover, A (2003) African swine fever and classical swine fever: a review of the pathogenesis. ...
AUSTRIA - Some newly born piglets shiver even when they are kept warm. So-called "shaking piglets" have symptoms that resemble those of the classical swine fever, with extensive damage to the brain and the spinal cord.
Dr. Dilip Kumar Sarma received his B.V.Sc &A.H. Degree from Assam Agricultural University in 1978 securing first class first position. He did his M.V.Sc and Ph.D degrees in Veterinary Bacteriology and Virology from Punjab Agricultural University, Ludhiana, India in 1981 and 1987 respectively. He had one year post doctoral research training at the AFRC Institute for Animal Health, Pirbright Laboratory, Surrey, U.K. under Commonwealth Govt. Scholarship. He has worked as Lecturer, Asstt. Professor, Virologist and as a Professor in the Department of Microbiology, Assam Agricultural University, Khanapara, Guwahati, since 2004. He has received the National Fellow Award of the Indian Council of Agricultural Research, New Delhi, India to work in a project on Classical swine fever and he has been working in the project since 2005. He has guided four Ph.D students, published two textbooks and 165 research papers in the National and International Journals and several popular scientific articles. He has ...
Hog Cholera (Classical Swine Fever). Sandra Axiak and Carolin Winter. Definition of hog cholera:. highly contagious viral disease of swine can cause acute, chronic, or congenital disease considered a foreign animal disease. Foreign animal disease (FAD):. Definition: Slideshow 113381 by flora
Virions from hog cholera virus (HCV), a member of the genus Pestivirus, were analyzed by using specific antibodies. The nucleocapsid protein was found to be a 14-kDa molecule (HCV p14). An equivalent protein could also be demonstrated for virions from another pestivirus, bovine viral diarrhea virus. The HCV envelope is composed of three glycoproteins, HCV gp44/48, gp33, and gp55. All three exist in the form of disulfide-linked dimers in virus-infected cells and in virions; HCV gp44/48 and gp55 each form homodimers, whereas gp55 is also found dimerized with gp33. Such complex covalent interactions between structural glycoproteins have not been described so far for any RNA virus. ...
Background The genus pestivirus within the family Flaviviridaeincludes bovine viral diarrhoea virus (BVDV) types 1 and 2, border disease virus (BDV) and classical swine fever virus. The two...
occurs in South America, Asia (including Indonesia) and certain European countries. Information on current country status can be obtained from the OIE World Animal Health Information Database. The last time CSF occurred in Australia was in 1962. Outbreaks have recently been reported in Bulgaria (in wild species), Israel and Lithuania.. Classical swine fever virus is a highly contagious Pestivirus which only infects swine, and is antigenically related to border disease virus and bovine viral diarrhoea virus. Pig to pig transmission is most common but CSF can also be spread by aerosol, swill feeding and mechanically by insects and fomites. Swill feeding of peri-urban pigs is a likely method of re-introduction of this virus to Australia and hence CSF may first be encountered by a veterinary practitioner servicing these areas. Strains vary greatly in their virulence. The last outbreak in Australia was caused by a mild strain that was detected only by a reported increase in fevered carcasses at ...
In 2016, two small-scale fattening pig farms (about 200 or 300 American Landrace pigs in total), locating in Guangdong province (southern China) and Jilin province (northern China) separated by more than 3, 000 km in distance (Fig. 1), suffered from severe respiratory disease (SRD). Pigs (2-3 months old) on both farms have received immunizations against PCV2, pseudorabies virus (PRV), classical swine fever virus (CSFV) and type 2 porcine reproductive and respiratory syndrome virus (PRRSV). However, the morbidity rate of pigs on the two farms was approximately 60%, the mortality in affected pigs was about 80%. From autopsy results of 18 individual dead pigs (n = 8 for farm A, n = 10 for farm B) (Additional file 1: Table S1), the similar macroscopic lesions were concentrated in the lungs and lymph nodes, which was characterized by PRRSV- or PCV2-like lesions including pulmonary interstitial widening, congestion and lymphadenopathy bleeding. These 18 pig lung samples were defined as the samples ...
APHIS recognizes the prevalence of CSF in Guatemala and responded immediately to their request for assistance to help control their latest outbreak," said Dr. John R. Clifford, USDAs Chief Veterinary Officer. "We sent a team of subject matter experts to assess the situation and concluded that the use of much-needed vaccine would help in containing the spread of the disease.". On March 19, APHIS donated the vaccines based on a request for assistance from the Guatemalan Chief Veterinary Officer, Dr. Humberto Maldonado, to help Guatemala control the spread of CSF there.. This assistance will help control and limit spread of CSF in Guatemala and neighboring countries. Among these countries are Mexico, currently working to control and eradicate the disease, and the United States, which has been free of CSF for over 30 years. Thus, this assistance extends beyond Guatemala and contributes to safeguarding animal health throughout Central and North America.. "With trade opportunities increasing each ...
swine fever virus N(pro) protein: has autoproteolytic activity; inhibits double-stranded RNA-mediated apoptosis and IFN-alpha/beta induction; GenBank AF144472
Exotic animal diseases (EADs) are characterized by their capacity to spread global distances, causing impacts on animal health and welfare with significant economic consequences. We offer a critique of current import risk analysis approaches employed in the EAD field, focusing on their capacity to assess complex systems at a policy level. To address the shortcomings identified, we propose a novel method providing a systematic analysis of the likelihood of a disease incursion, developed by reference to the multibarrier system employed for the United Kingdom. We apply the network model to a policy-level risk assessment of classical swine fever (CSF), a notifiable animal disease caused by the CSF virus. In doing so, we document and discuss a sequence of analyses that describe system vulnerabilities and reveal the critical control points (CCPs) for intervention, reducing the likelihood of U.K. pig herds being exposed to the CSF virus. ...
How BVDV affects fetal development depends on the timing of maternal infection during pregnancy. The eyes and central nervous system are targets of the virus, and characteristic deformations of the brain and skull are observed. These deformities include hydranencephaly, hydrocephalus, and microencephaly [6].. BVDV is not transmissible to people but can infect a number of ruminants. Other species in the pestivirus family - siblings to bovine viral diarrhea - include border disease of sheep and classical swine fever in pigs. All of these pestiviruses can cause birth deformities.. Another fascinating aspect of pestiviruses is that they can affect host immunity during infection. BVDV is capable of becoming a "persistent infection" that is never fully cleared from the body. Persistent infection can happen in a number of ways. BVDV can manipulate the mechanisms that identify pathogens in the body. The virus is therefore camouflaged as "self" and avoids targeting by the immune system [7]. Calves may be ...
Imports of pork rinds, a snack food made from deep-fried pork skins, are so well cooked that the risk of transmitting hog diseases, such as foot-and-mouth disease, swine vesicular disease, African swine fever and classical swine fever, is non-existent, said the U.S. Department of Agriculture's Animal and Plant Health Inspection Service.
The European Commission said that given the serious impact that animal disease outbreaks can have on human health, society, the economy and trade, the allocation of EU co-financing will continue to assist national authorities to put in place precautionary measures, disease surveillance and eradication programmes, at national and European level.. Overall 142 programmes have been selected for EU funding: Bovine Tuberculosis (about €56 million); Transmissible Spongiform Encephalopathies (about €42 million); Rabies (€27.5 million); Salmonellosis (about €17.5 million); Bovine Brucellosis (about €10 million); Classical Swine Fever (€3 million); Avian Influenza (€2.5 million); Bluetongue (€1.5 million); African Swine Fever and Swine Vesicular Disease in Italy (about €850.000).. EU co-financing has resulted in a continuous decrease in the number of cases of diseases, such as Salmonellosis (the second most frequently reported zoonotic disease in humans) and Transmissible Spongiform ...
Swine leukocyte antigen (SLA) class I molecules play a crucial role in generating specific cellular immune responses against viruses and other intracellular pathogens. They mainly bind and present antigens of intracellular origin to circulating MHC I-restricted cytotoxic T lymphocytes (CTLs). Binding of an appropriate epitope to an SLA class I molecule is the single most selective event in antigen presentation and the first step in the killing of infected cells by CD8+ CTLs. Moreover, the antigen epitopes are strictly restricted to specific SLA molecules. In this study, we constructed SLA class I complexes in vitro comprising viral epitope peptides, the extracellular region of the SLA-1 molecules, and β2-microglobulin (β2m) using splicing overlap extension polymerase chain reaction (SOE-PCR). The protein complexes were induced and expressed in an Escherichia coli prokaryotic expression system and subsequently purified and refolded. Specific binding of seven SLA-1 proteins to one classical swine fever
Romania will be resuming on-farm vaccinations against classical swine fever (CSF) soon, the website of the US Department of Agriculture says.
At the IVMR, a rich past and an intense present complement each other. József Csontos (1889-1962), founding director of the then-called Animal Health Research Institute, together with Aladár Aujeszky developed the so-called carbolic glycerinated vaccine against rabies containing fixed virus. After World War II, he played a pivotal role in the eradication of infectious animal diseases, above all classical swine fever and porcine erysipelas, and also took part in organizing the healthcare of large stocks in intensive animal farming. Among past researchers of the institute, one of worldwide fame was Domokos Derzsy (1914-1975), whose scientific topics of interest spanned almost the entire spectrum of infectious animal diseases. He diagnosed and described several poultry diseases unknown in Hungary before, one of these was that caused by goose Parvovirus, which was named Derzsys disease in honor of his internationally significant research on this pathogen. Adorján Bartha (1923-1996) also worked ...
At the IVMR, a rich past and an intense present complement each other. József Csontos (1889-1962), founding director of the then-called Animal Health Research Institute, together with Aladár Aujeszky developed the so-called carbolic glycerinated vaccine against rabies containing fixed virus. After World War II, he played a pivotal role in the eradication of infectious animal diseases, above all classical swine fever and porcine erysipelas, and also took part in organizing the healthcare of large stocks in intensive animal farming. Among past researchers of the institute, one of worldwide fame was Domokos Derzsy (1914-1975), whose scientific topics of interest spanned almost the entire spectrum of infectious animal diseases. He diagnosed and described several poultry diseases unknown in Hungary before, one of these was that caused by goose Parvovirus, which was named Derzsys disease in honor of his internationally significant research on this pathogen. Adorján Bartha (1923-1996) also worked ...
26 September 2000 Unigate blames losses on swine fever UNIGATE has blamed the outbreak of swine fever for preventing its pork processing plant in North Yor
Countries across Asia are struggling to contain an outbreak of swine fever, which is threatening the livelihoods of millions of families that rely on pig farming. The highly contagious and incurable virus is deadly to pigs but not dangerous to humans. The disease originally spread from Africa
Another case of swine fever was detected in Manta in Cahul district. The virus was confirmed by laboratory analysis after a man announced to the National Agency for Food Safety in the district that he had found his pig dead.Immediately, the emergency comm
Global price cycle, Swine Fever outbreak in S Korea, China bans Dutch food imports, USDA forecasts, EU vets vote for new Spanish and German CSF measures, UK farmers suffer second FMD scare.....
Sigma-Aldrich offers abstracts and full-text articles by [Jiangnan Li, Yajuan Dai, Shuai Liu, Huancheng Guo, Tiedong Wang, Hongsheng Ouyang, Changchun Tu].
In der medizinischen Versorgung bekommt die Ernährung einen immer größeren Stellenwert. Zum einen sind heute Nahrungsmittelunverträglichkeiten häufiger anzutreffen, andererseits wird eine Ernährungsth
African swine fever. African swine fever (ASF) is a highly contagious hemorrhagic disease of pigs that produces a wide range of clinical signs and lesions that closely resemble those of classical swine fever. Infection, with a highly variable virulence, causes, typically 3-15 days later, high fever, reddening of the skin (visible only in pale-skinned pigs), decreased appetite, listlessness, loss of coordination, vomiting, diarrhoea (sometimes bloody) and eye discharges. Mortality rates can be as high as 100% in domestic pigs and wild boar, with death occurring in less than a week. In some cases, sudden death may be the only clinical sign.. The disease was first described after European settlers brought pigs into areas endemic with ASFV and, as such, is an example of an emerging infection. Although ASFV can be adapted to grow in cells from different species, it does not replicate readily in any species other than swine. Fortunately, African swine fever is not a human health threat.. The virus : ...
Main Article. The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.. ...
African swine fever virus, illustration. This virus is a member of the iridovirus group that causes African swine fever. Unlike other DNA- containing vertebrate viruses (except the poxviruses), the iridovirus replicates in the host cells cytoplasm (most others replicate in the nucleus). - Stock Image F016/8841
We describe a horizontal survey of African swine fever virus (ASFV) prevalence and risk factors associated with virus infection in domestic pigs in two contrasting production systems in Kenya. A free range/tethering, low input production system in Ndhiwa District of South-western Kenya is compared with a medium input stall fed production system in Kiambu District of Central Kenya. Analysis of variance (ANOVA) of data derived from cluster analysis showed that number of animals, number of breeding sows and number of weaner pigs were a significant factor in classifying farms in Nhiwa and Kiambu. Analysis of blood and serum samples using a PCR assay demonstrated an average animal level positivity to ASFV of 28% in two independent samplings in South-western Kenya and 0% PCR positivity in Central Kenya. No animals were sero-positive in either study site using the OIE indirect-ELISA and none of the animals sampled exhibited clinical symptoms of ASF. The farms that contained ASFV positive pigs in Ndhiwa ...
The role of the ancestral sylvatic cycle of the African swine fever virus (ASFV) is not well understood in the endemic areas of eastern Africa. We therefore analysed the ASF infection status on samples collected from 51 free-ranging warthogs (Phacocherus africanus) and 1576 Ornithodorus porcinus ticks from 26 independent warthog burrows at a single ranch in Kenya. Abattoir samples from 83 domestic pigs without clinical symptoms, originating from specific locations with no recent reported ASF outbreaks were included in this study. All samples were derived from areas of central Kenya, where ASF outbreaks have been reported in the past. Infection with ASFV was confirmed in 22% of O. porcinus pools, 3.22% of adult warthog serum samples and 49% of domestic pig serum samples by using p72-based PCR. All of the warthog sera were positive for anti-ASFV antibodies, investigated by using ELISA, but none of the domestic pig sera were positive. Twenty O. porcinus-, 12 domestic pig- and three warthogderived ...
1. Prolonged and systematic examination of blood from swine with hog cholera has failed to reveal any formed element that could be identified with the etiological virus. Culture has likewise been unsuccessful.. 2. The quantitative blood changes in hog cholera consist in a slowly progressive anemia, usually moderate in degree, and a rapidly progressive severe leucopenia affecting cells of the polymorphonuclear series most markedly but also including those of the lymphocytic series.. 3. Incubation of hog cholera blood results in a further progress of the leucopenia, in vitro, if heparin has been used as the anticoagulant, but there is no significant change if potassium oxalate or sodium citrate has been used.. 4. Consideration of the leucocytic reactions prevailing in experimental infection with B. suisepticus, in infectious enteritis, in swine influenza, following successful immunization against hog cholera, and following infection of cholera-sick swine with secondary invaders indicates that the ...
Aujeszkys disease, usually called pseudorabies in the United States, is a viral disease in swine that has been endemic in most parts of the world. It is caused by Suid herpesvirus 1 (SuHV1). Aujeszkys disease is considered to be the most economically important viral disease of swine in areas where classical swine fever (hog cholera) has been eradicated. Other mammals, such as cattle, sheep, goats, cats, dogs, and raccoons, are also susceptible. The disease is usually fatal in these animal species. The term "pseudorabies" is found inappropriate by many people, as SuHV1 is a herpesvirus and not related to the rabies virus. Research on SuHV1 in pigs has pioneered animal disease control with genetically modified vaccines. SuHV1 is now used in model studies of basic processes during lytic herpesvirus infection, and for unravelling molecular mechanisms of herpesvirus neurotropism. In 1902, a Hungarian veterinarian, Aladár Aujeszky, demonstrated a new infectious agent in a dog, ox, and cat, and ...
November 24, 2010 - The U.S. Department of Agricultures Animal and Plant Health Inspection Service (APHIS) is amending its regulations governing the importation of certain animals and animal products by adding the Brazilian State of Santa Catarina to the list of regions we recognize as free of foot-and-mouth disease (FMD), rinderpest, swine vesicular disease (SVD), classical swine fever (CSF) and African swine fever (ASF). APHIS is also adding Santa Catarina to the list of regions that are subject to certain import restrictions on meat and meat products because of their proximity to or trading relationships with rinderpest- or FMD-affected countries. These actions will update the disease status of Santa Catarina with regard to FMD, rinderpest, SVD, CSF and ASF while continuing to protect the United States from an introduction of those diseases by providing additional requirements for live swine, pork meat, pork products, live ruminants, ruminant meat and ruminant products imported into the ...
Vaccination of wildlife has been studied for at least 50 years since the earliest attempts at oral vaccination against classical swine fever (CSF) (reviewed by Kaden et al. [32]). Although routine vaccination against CSF is prohibited in domestic pigs within the European Union, emergency vaccination is permitted. Vaccination has become more widely accepted as a potential option for the management of disease in wildlife populations following its successful employment in the control of sylvatic rabies [33]. Although currently very few vaccines for wildlife species have been licensed, work is on-going in a number of areas. Recent examples include experimental vaccination of wild white-footed mice (Peromyscus leucopus) [34], a reservoir host species of the human Lyme disease agent (Borrelia burgdorferi), American robins (Turdus migratorius) [35], an amplification host for West Nile Virus, and bison (Bison bison) and elk (Cervus elaphus) against brucellosis [36]. A more extensive review of the ...
APHIS has determined that the Republic of Cyprus is free of foot-and-mouth disease (FMD), rinderpest, and swine vesicular disease (SVD), and is low risk for classical swine fever (CSF). This determination will allow the importation of meat and meat products into the United States from Cyprus under certain restrictions, while continuing to mitigate the risk of introducing these diseases into the United States. While this action covers the majority of the country, it does not include areas north of the United Nations buffer zone, known as the Green Line ...
Outbreaks of infectious animal diseases within the last 10-15 years in areas with intensive livestock production have shown how vulnerable the production systems can be when confronted with an outbreak of a highly infectious disease such as avian influenza, foot and mouth disease or classical swine fever. The veterinary administrations of the Nordic and Baltic countries have established contingency plans; the objectives of the plans include:. - to protect animal and human health. - to minimize economic loss for the livestock sector and the society as a whole. - to minimize damage to the environment.. This publication provides information on measures to be considered in contingency planning; the measures take into account:. - the pre-epidemic period; disease prevention. - the epidemic period; disease eradication. - the post-epidemic period; regaining of animal health status.. ...
Outbreaks of infectious animal diseases within the last 10-15 years in areas with intensive livestock production have shown how vulnerable the production systems can be when confronted with an outbreak of a highly infectious disease such as avian influenza, foot and mouth disease or classical swine fever. The veterinary administrations of the Nordic and Baltic countries have established contingency plans; the objectives of the plans include:. - to protect animal and human health. - to minimize economic loss for the livestock sector and the society as a whole. - to minimize damage to the environment.. This publication provides information on measures to be considered in contingency planning; the measures take into account:. - the pre-epidemic period; disease prevention. - the epidemic period; disease eradication. - the post-epidemic period; regaining of animal health status.. ...
We applied social network analysis to pig trader networks on the Kenya-Uganda border. Social network analysis is a recently developed tool, which is useful for understanding value chains and improving disease control policies. We interviewed a sample of 33 traders about their experiences with trade and African swine fever (ASF), analyzed the networks they generated in purchasing pigs and selling pork and their potential contribution to modulating dissemination of the ASF virus (ASFV). The majority of the traders were aware of clinical signs of ASF and the risk of trade transmitting ASFV. Most said they avoided buying pigs from ASF outbreak villages or sick pigs but their experiences also indicated that inadvertent purchase was relatively common. Traders had early knowledge of outbreaks since they were contacted by farmers who had heard rumours and wanted to sell their pigs to avoid the risk of them dying. Individual traders bought pigs in up to nine villages, and up to six traders operated in a ...
TAGUM CITY-The City Government of Tagum assured the public that there is no reported swine fever virus in this city, following the concern raised by several sectors over the reported cases in some parts of the country.. Dr. Jesus Edullantes allayed fears of the public and strongly emphasized that the virus has not reached the local hog industry in the city.. Hinged on Administrative Order 04, s-2019 of the Department of Agriculture (DA), the local government unit of Tagum, headed by Mayor Allan Rellon, convened on Friday, August 20, 2019, the African Swine Fever Task Force (ASF-TF) which was created to ensure the continued implementation of precautionary measures relative food safety and food security in view of the reported increasing swine mortalities in the country.. The inter-agency task force, which is chaired by the City Veterinarian, planned to stringently enforce the said measures to ensure that transportation of live animals, meat products and meat by-products is prohibited unless ...
African swine fever has ravaged Chinas pig population, and the countrys consumers are feeling the pain. Some are even switching to other meats as the dietary staple becomes unaffordable.
Around a quarter of the worlds pigs are expected to die from African swine fever as authorities grapple with a complex disease spreading rapidly in the globalization era, the World Organization for Animal Healths president said Thursday.. A sharp reduction in the worlds pig population would lead to possible food shortages and high pork prices, and it might also cause shortfalls in the many products made from pigs, such as the blood-thinner heparin thats used in people, said Dr. Mark Schipp, the organizations president.. The diseases spread in the past year to countries including China, which has half the worlds pigs, had inflamed a worldwide crisis, Schipp told reporters at a briefing in Sydney.. "I dont think the species will be lost, but its the biggest threat to the commercial raising of pigs weve ever seen," he said. "And its the biggest threat to any commercial livestock of our generation.". African swine fever, fatal to hogs but no threat to humans, has wiped out pig herds in ...
The gangs are taking advantage of a highly contagious disease that has spread across much of the country and disrupted the worlds biggest pork market, reports Reuters.. The scam involves dumping dead pigs on farms and then spreading rumours that the farms are infected with African swine fever, which is often fatal for pigs but harmless for humans.. The gangs then pressure farmers to sell their hogs at lower prices, violating farmers rights and affecting normal pig production, the Ministry of Agriculture and Rural Affairs said in a statement.. The ministry did not give more details but it urged anyone who witnessed such activities to alert the authorities.. "All localities should be vigilant and actively guard against it," it said.. Up to half of Chinas breeding pigs have either died from African swine fever or been slaughtered because of the spreading disease, twice as many as officially acknowledged, Reuters reported last month. ...
SYDNEY (AP) - Around a quarter of the worlds pigs are expected to die from African swine fever as authorities grapple with a complex disease spreading rapidly in the globalization era, the World Organization for Animal Healths president said Thursday.. A sharp reduction in the worlds pig population would lead to possible food shortages and high pork prices, and it might also cause shortfalls in the many products made from pigs, such as the blood-thinner heparin thats used in people, said Dr. Mark Schipp, the organizations president.. The diseases spread in the past year to countries including China, which has half the worlds pigs, had inflamed a worldwide crisis, Schipp told reporters at a briefing in Sydney.. "I dont think the species will be lost, but its the biggest threat to the commercial raising of pigs weve ever seen," he said. "And its the biggest threat to any commercial livestock of our generation.". African swine fever, fatal to hogs but no threat to humans, has wiped out ...
SEJONG -- It is now close to one month since the nations first case of African swine fever was confirmed in Paju, Gyeonggi Province, on Sept. 17.The number of outbreaks of the deadly animal virus came to 13 as of 4 p.m., Oct. 8 -- eight in Gyeonggi Province and five in Incheon. All the affected regions are close to the inter-Korean border: Paju, Gyeonggi Province, with five cases; Yeoncheon, Gyeonggi Prov...
(Bloomberg) -- As the coronavirus sweeps across the globe sickening humans, scientists are making progress on developing tests that could help combat a different deadly disease: African swine fever, which has been ravaging hog herds. The U.S.
The supply of pork in China may remain tight for the next few years, a leading pig industry expert said recently, citing unprecedented losses due to African swine fever, which has spread around the country since August last year.
An African swine fever outbreak is threatening Chinas massive pork industry. Angus Gidley-Baird of RaboResearch Food and Agribusiness discusses.
China will auction 10,000 tonnes of reserve pork this week, the commerce ministry said, in a bid to control the fallout from an outbreak of African swine fever that has sent prices soaring and hit supplies of the meat ahead of a key holiday. In a statement published on its website Tuesday night, a state-owned
UN2900 Indicative Examples of Infectious Substances Included in Category A UN2900 Infectious substance, affecting animals African swine fever virus...
This compilation (including design, introductory text, organization, and descriptive material) is copyrighted by University of Wisconsin System Board of Regents.. This copyright is independent of any copyright on specific items within the collection. Because the University of Wisconsin Libraries generally do not own the rights to materials in these collections, please consult copyright or ownership information provided with individual items.. Images, text, or other content downloaded from the collection may be freely used for non-profit educational and research purposes, or any other use falling within the purview of "Fair Use".. In all other cases, please consult the terms provided with the item, or contact the Libraries. ...
Daily New York Times connects, in a wide investigative article, the nowadays swine flu wave and the one that affected Romanian farms in 2007. That particular strain affects only hogs, but - hotnews, news, articles, press review, politics, economics, sport
The veterinary department said that 57 cases of ASF have been registered in seven regions since the start of 2012: 23 in Krasnodar territory, 19 in Tver, 11 in Volgograd region and one-off cases in Karelia and Kalmykia, Rostov and Yaroslavl regions.. The ASF situation worsened between June 19 and September 8. During this time 50 cases were identified in five regions - 20 in Krasnodar territory, 19 in Tver region, 9 in Volgograd and one each in Rostov and Yaroslavl regions. So far two cases of ASF have been eliminated in household farms, so there are now 48 cases of infection.. Despite a bank, household and small farms continue to feed pigs with fodder containing raw pig or wild boar slaughter products. "A major risk factor is that farm owners and managers are still underestimating the danger of the spread of ASF and are breaching biological protection of industrial zone regimes," the report says.. Fyodorov recommended that the example at Krasnodar territory be considered where careless farmers ...
Canadian hogs, Suspected Swine Fever outbreak in Japan, Americans eat too much meat say cancer scientists, McDonalds sued over use of trans fat, Global price cycle, WTO members urged to meet deadline ...../
U.S. soybean exports have fallen in the past year in part because of the drop in exports to China due to tariffs and swine fever. U.S.
Microarray technology can be useful for pathogen detection as it allows simultaneous interrogation of the presence or absence of a large number of genetic signatures. However, most microarray assays are labour-intensive and time-consuming to perform. This study describes the development and initial evaluation of a multiplex reverse transcription (RT)-PCR and novel accompanying automated electronic microarray assay for simultaneous detection and differentiation of seven important viruses that affect swine (foot-and-mouth disease virus [FMDV], swine vesicular disease virus [SVDV], vesicular exanthema of swine virus [VESV], African swine fever virus [ASFV], classical swine fever virus [CSFV], porcine respiratory and reproductive syndrome virus [PRRSV] and porcine circovirus type 2 [PCV2 ...
Bovine viral diarrhea (BVD) or bovine viral diarrhoea (UK English), and previously referred to as bovine virus diarrhoea (BVD), is a significant economic disease of cattle that is endemic in the majority of countries throughout the world. The causative agent, bovine viral diarrhea virus (BVDV), is a member of the Pestivirus genus of the family Flaviviridae. BVD infection results in a wide variety of clinical signs, due to its immunosuppressive effects, as well as having a direct effect on respiratory disease and fertility. In addition, BVD infection of a susceptible dam during a certain period of gestation can result in the production of a persistently infected (PI) fetus. PI animals recognise intra-cellular BVD viral particles as self and shed virus in large quantities throughout life; they represent the cornerstone of the success of BVD as a disease. BVDV is a member of the Pestivirus genus, belonging to the family Flaviviridae. Border disease virus (sheep) and classical swine fever virus ...
Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch.
MANILA (Reuters) - The Philippines Department of Agriculture on Tuesday threatened legal action against hog traders ignoring strict animal quarantine rules as it confirmed new cases of African swine fever infections in metropolitan Manila and a northern province.. Agriculture Secretary William Dar said the highly contagious and deadly disease was detected in another backyard hog-raising business in Quezon City in the countrys capital.. Dar, who also confirmed African swine fever outbreaks in Pangasinan province in the northern Philippines, has ordered the culling of pigs in affected areas.. The incurable disease is wreaking havoc on hog industries in China and Southeast Asia and could also spell trouble for U.S. grain exporters supplying animal feeds to virus-hit countries such as Vietnam, Myanmar and the Philippines.. Dar told reporters hog traders transporting infected pigs were to blame for the rising number of African swine fever cases in the Philippines.. "All hog traders, the full force ...
STRASBOURG, France (Reuters) - France will start putting up fencing along part of its border with Belgium this weekend to prevent wild boars spreading African swine fever, a virulent livestock disease that could disrupt Europes large pig industry.. France has been on alert for African swine fever since Belgium detected the virus last month among wild boars a few kilometers from the French border.. Belgium decided to slaughter several thousand pigs in its contaminated zone to prevent the virus reaching farm herds, but it is already facing embargos on its pork exports from countries like South Korea and China, which is also grappling with an outbreak of the disease.. French authorities have banned hunting and other activities in a border zone and the prefecture in the Meurthe-et-Moselle region will start installing fencing on Saturday, a prefecture official and a hunting association said on Friday.. The fencing would cover part of the border and be supported by repellent products on roads and ...
Nearly 800 wild boar carcasses infected with African swine fever (ASF) have been found in Estonias forests in 2016, while an additional nearly 700 hunted wild boars have been documented as carrying the disease.
Michael S Denyer and Philip J Wilkinson, Institute for Animal Health, Pirbright Laboratory, Pirbright, UK. African swine fever (ASF) is a highly contagious acute hemorrhagic disease of domestic pigs caused by a large icosahedral DNA virus which produces a wide range of clinical signs. Protective immunity can be stimulated in vivo but classical neutralizing antibodies have not been demonstrated. The complete genome has been sequenced and some proteins that could enable the virus to evade the host immune response have been identified. There is no vaccine.. ...
China has banned imports of pigs, wild boars and related products from Slovakia to prevent the spread of African swine fever from the European country, China
Complete feed accounts for 42% of hog feed consumption," eFeedLinks Eric Brooks noted. Another eFeedLink analyst, Shi Tao, stated that, "In June 2019, nine (out of 22) provinces slashed the output of complete hog feed by more than 50% compared with June 2018. The output of another nine provinces decreased by more than 20%. Total complete hog feed output fell by 32.4% year-on-year.". Brooks said that the sharp drops in hog feed production is in line with eFeedLinks July 2019 Livestock Tracker, which stated: "Since peaking at 492 million head in January, African swine fever mortality and culling slashed inventories by 7.1%. Expect an additional ASF-induced inventory fall of 20% to 25% from current levels before they stabilise.". This downtrend in feed production could explain the recent losses of Chinese feed maker Beijing Dabeinong Technology Grup Co. Ltd, which produced 4.6 million tonnes of feed - mostly for pigs - last year. On August 21, the company reported a 67.67% drop in first-half net ...
The spread of African swine fever has not only ravaged the Asian pig population, but also sent international pork prices rocketing and hit animal feed markets such as corn and soybeans.. It has also weighed on results of agricultural commodity groups due to weaker feed demand for hog breeding.. Chinas hog herd was more than 40% smaller in September than a year earlier, its farm ministry said earlier this month. But several in the industry believe the losses are much greater.. Beijing issued a series of policies in September aimed at supporting national hog production and securing meat supplies.. Eloit said the measures were adequate but needed to be fully implemented.. "There is a difference between what is decided on paper - I do not think there is any concern here - and how we actually get to apply them on the ground especially in countries that are very large, which have a wide variety of production," she said. In Europe, the situation is different because outbreaks mainly concern wild ...
Serum samples taken from recently deceased pigs in Shan State tested positive for African swine fever, marking the virus first confirmed appearance in Myanmar.
Veterinary medicines maker ECO Animal Health Group said on Monday its business in China was hit by an outbreak of African swine fever, while the ongoing U.S.-China trade war squeezed margins in the United States.
Nagsilipana sa internet ang mga tinatawag na probiotic supplements na binebenta para umano makaiwas sa African swine fever ang mga alagang baboy.
Poland on Wednesday confirmed its first cases of deadly swine fever in domestic pigs, as the World Trade Organisation reviewed a Russian embargo on EU pork imports imposed over the disease.
SEOUL: South Korea on Tuesday reported its first cases of African swine fever, becoming the latest country hit by the disease that has killed pigs from China to North Korea, pushing up pork prices worldwide.
CBRNe World provides those tasked with defending against CBRN and IED threats with the essential practical, scientific and political information. Access the current and previous issues of the magazine by registering as a member.
class="post-template-default single single-post postid-386589 single-format-standard custom-background group-blog masthead-fixed full-width singular wpb-js-composer js-comp-ver-6.2.0 vc_responsive ...
This patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results.
Infected pigs were found in two towns near the Philippine capital Manila and authorities have culled more than 7,000 pigs within a one-kilometer (0.6-mile) radius, said Agriculture Secretary William Dar.
RaboResearch Food & Agribusiness published its annual global animal protein outlook. In general, African swine fever (ASF) overwhelms the outlook for 2020 – as it has done during 2019 – and will pull down overall growth, as well as bring uncertainty to all markets.
Looking for online definition of hog cholera vaccines in the Medical Dictionary? hog cholera vaccines explanation free. What is hog cholera vaccines? Meaning of hog cholera vaccines medical term. What does hog cholera vaccines mean?
The outbreaks of African Swine Fever in Bulgaria have resulted in more than 100 000 pigs being culled in the northern part of the country, Bulgarian National Television (BNT) said on the evening of August 1.. Estimates from before the outbreak of African Swine Fever put the number of registered pigs in Bulgaria at a maximum 600 000.. The Bulgarian Food Safety Agency has begun checks in small towns in northern Bulgaria to see if farmers have voluntarily got rid of their pigs, the report said.. The deadline for doing so in districts in that part of Bulgaria expired on July 31. Failure to comply means a fine of 100 to 1000 leva (about 50 to 500 euro).. Efforts by veterinary authorities in Rousse, the largest city on Bulgarias Danube border, are currently aimed at controlling the outbreak of African Swine Fever in the town of Byala, where a sick pig was found in a farmyard. In the area, 140 animals will be euthanised at six unregistered small farms.. However, employees of the Regional Food Safety ...
African swine fever is highly contagious and nearly 100% fatal to swine herds. It occurs among pigs and wild boars, transmitted by ticks and direct contact between animals. There is no vaccine for the disease, but it does not affect humans.. The first outbreak of African swine fever in East Asia was reported in China in early August 2018. Since then, the deadly virus has spread to all Chinese provinces and regions, as well as to other Asian nations, including Vietnam and the Philippines.. South Korea, Asias fourth-largest economy, does not import any pork products or live pigs from China due to Chinas history of foot-and-mouth disease outbreaks. It mainly imports from the United States and Germany, and pork imports account for about a third of the countrys total pork supplies.. Although this is the first time African swine fever has hit South Korea, an incidence of foot-and-mouth disease was confirmed in March 2018 at a hog farm, the countrys first discovery since February 2017.. South Korea ...
African swine fever is a devastating hemorrhagic fever of pigs, caused by the African swine fever virus (ASFV). In Africa, the presence of a sylvatic cycle involving warthogs and soft ticks means that the risk of introduction of ASFV into domestic swine is always present. Bushpigs (Potamochoerus larvatus) are nocturnal, susceptible to ASFV and share a natural interface with both warthogs and domestic pigs. The role of the bushpig in the epidemiology of ASFV if any is not understood, yet control strategies of the disease in areas with probable contact between bushpigs and domestic pigs would depend on such information. This study used a molecular and ecological approach to investigate the role of the bushpig in the epidemiology of African swine fever at the wildlife-livestock interface in Uganda. The GPS/GSM tracking collars were used to monitor the movement patterns of free-ranging domestic pigs and bushpigs. Four free-ranging domestic pigs and five bushpigs were collared and their movements ...
African swine fever is spreading slowly in the Baltic countries and Poland, according to the latest epidemiological data analysed by these Member States and EFSA.. The disease is spreading at about 2 km a month in Latvia and Estonia, and 1 km a month in Lithuania and Poland. In addition, the number of infected animals found among hunted wild boar is very low (up to 3%). The outbreaks in wild boar in the Baltic countries and Poland can therefore be defined as a "small-scale epidemic".. The report covers cases reported between 2014 and 2016.. "This report is the outcome of a fruitful cooperation with Member States. We look forward to continuing investigations on this disease, which has serious socio-economic consequences in affected countries," says Andrea Gervelmeyer, veterinary epidemiologist at EFSA.. The first cases of African swine fever were identified in Lithuania and in eastern Poland at the beginning of 2014. The disease was subsequently reported in Latvia and Estonia. No additional ...
The invention disclosed herein presents an antigen-capture immunoassay that utilizes serum, plasma, milk, urine, saliva, or other bodily fluid samples to identify cattle infected with the Bovine Viral Diarrhea Virus (BVDV). The results of this assay allow an effective, reliable, quick, and cost efficient way to identify, and thereby remove, infected cattle and/or other ruminants from otherwise uninfected herds. The BVD virus causes an acute enteric disease with a variety of clinical manifestations, and is closely related to sheep border disease virus (BDV) and hog cholera virus (HCV). The traditional method of detecting infected animals, including persistently infected (PI) carriers, has been through .the .use of virus isolation procedures. While .this older test methodology can detect infected animals, the virus isolation test can only be performed by highly trained technicians in a highly specialized laboratory facility. The kit disclosed herein uses ELISA methodology, employs the BVDV antigen
Introduction. Classical and African swine fever (CSF, ASF) are the two most feared diseases of swine worldwide. Both are characterised by high mortality and are transboundary diseases that can have devastating effects on livelihoods that depend on pig production (Costard et al. 2009; Moennig 2000). Although they are caused by completely unrelated viruses, the pathogenesis of the two diseases is similar, therefore the clinical and pathological manifestations are strikingly alike (Moennig 2000; Penrith, Thomson & Bastos 2004a). CSF is caused by a single-stranded RNA virus of the genus Pestivirus, family Flaviviridae, while ASF is caused by a large, double-stranded DNA virus that was only allocated to its own genus, Asfivirus, the only member of the family Asfarviridae, in 1998 (Dixon et al. 2005). Both viruses affect only members of the pig family (Suidae) (Moennig 2000; Plowright, Thomson & Neser 1994). Both are highly contagious diseases in pigs and their ancestors, the Eurasian wild boar (Sus ...
"Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ...
The classical swine fever virus UTR described appears to be longer at the 5' end than other pestivirus UTRs. This family ... "Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ...
... interacting protein involved in classical swine fever virus growth". Journal of Virology. 87 (4): 2072-80. doi:10.1128/JVI. ... study found that a Sus scrofa PRR29-like protein interacts with the N-terminal protease of classical swine fever virus (CSFV). ...
Klassisches Schweinepest-Virus - en. Classical swine fever virus (CSFV) oder Hog cholera virus ... Usutu-Virus - en. Usutu virus (USUV), Zika-Virus - en. Zika virus (ZIKV), sowie Gelbfieber-Virus - en. Yellow fever virus (YFV) ... Genus ‚Negevirus', mit Species ‚Blackford virus', ‚Bofa virus', ‚Buckhurst virus', ‚Marsac virus', sowie ‚Muthill virus'[53] ... Sorghum mosaic virus (SrMV), Lily-Mottle-Virus - en. Lily mottle virus (LMoV), sowie Sellerie-Virus Y - en. Apium virus Y (ApVY ...
Foot-and-mouth disease Hepatitis B Classical swine fever virus White spot syndrome virus Staphylococcus aureus (common cause of ... In 2007, a classical swine fever virus (CSFV) was produced in C. reinhardtii, providing immunity in mice that were ... however algae may act as a useful platform for novel vaccines or replacing extremely expensive vaccines for viruses like HPV. ...
... bovine viral diarrhea virus NS3 endopeptidase, BVDV NS3 endopeptidase, classical swine fever virus NS3 endopeptidase, CSFV NS3 ... Xu, J.; Mendez, E.; Caron, P.R.; Lin, C.; Murcko, M.A.; Collett, M.S.; Rice, C.M. (1997). "Bovine viral diarrhea virus NS3 ... Tautz, N.; Kaiser, A.; Thiel, H.J. (2000). "NS3 serine protease of bovine viral diarrhea virus: characterization of active site ... Pestivirus NS3 polyprotein peptidase (EC 3.4.21.113, border disease virus NS3 endopeptidase, BDV NS3 endopeptidase, ...
GB virus D) Genus Pestivirus (type species Bovine virus diarrhea virus 1, others include Classical swine fever virus ( ... virus Uganda S virus Usutu virus Wesselsbron virus West Nile virus Yaounde virus Yellow fever virus Yokose virus Zika virus ... fever virus Phnom Penh bat virus Powassan virus Rio Bravo virus Royal Farm virus Saboya virus Sal Vieja virus San Perlita virus ... Apoi virus Aroa virus Bagaza virus Banzi virus Bouboui virus Bukalasa bat virus Cacipacore virus Carey Island virus Cowbone ...
Nipah virus infection, Rift Valley fever, capripox, lumpy skin disease, glanders, and classical swine fever. Animal Care - The ... Diseases of primary concern are: classical swine fever, African swine fever, Newcastle disease, and notifiable avian influenza ... classical swine fever, and Nipah and Hendra virus infections. The NCFAD has received designations by the World Organization for ... Hendra virus, Ebola virus and Rift Valley fever virus. The Section maintains a state of readiness for emergencies or outbreak ...
2007 Central Luzon hog cholera outbreak Animal viruses Classical Swine Fever, The Center for Food Security and Public Health / ... Classical swine fever (CSF) or hog cholera (also sometimes called pig plague based on the German word Schweinepest) is a highly ... doi:10.1016/S1090-0233(02)00112-0. CSF page of Pig Disease Information Centre (UK) Current status of Classical Swine Fever ... contagious disease of swine (Old World and New World pigs). Swine fever causes fever, skin lesions, convulsions, and usually ( ...
The clinical symptoms of ASFV infection are very similar to classical swine fever virus, and the two diseases normally have to ... African swine fever virus (ASFV) is the causative agent of African swine fever (ASF). The virus causes a haemorrhagic fever ... Viruses portal Animal viruses Denyer, M. S.; Wilkinson, P. J. (1998). "African Swine Fever". Encyclopedia of Immunology. p. 54 ... 2008). "African Swine Fever Virus". Animal Viruses: Molecular Biology. Caister Academic Press. ISBN 978-1-904455-22-6. Dixon, L ...
"Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ... nontranslated region of hepatitis A virus RNA: comparison with the IRES of encephalomyocarditis virus (EMCV)". J Virol. 68 (2 ... For influenza A virus, its primary method of action as an antiviral is to prevent the uncoating of viral genome which inhibits ... This results in a longer period required until maximum shedding of the virus is reached. This also results in cell death only ...
Border disease virus (sheep) and classical swine fever virus (pigs) are other members of this genus that also cause significant ... Ncp viruses can induce persistent infection in cells and have an intact NS2/3 protein. In cp viruses the NS2/3 protein is ... The virus therefore entered the fetal cells and, during immune system development, was accepted as self. In PIs the virus ... Animal viruses Fray; et al. (2000). The effects of bovine viral diarrhoea virus on cattle reproduction in relation to disease ...
... including classical swine fever virus, and Hepacivirus genus, including Hepatitis C virus. The SVV IRES RNA shares similarities ... Positive stranded RNA virus transcription is the method of transcription. The virus exits the host cell by lysis, and ... Virotherapy Oncolytic virus "Viral Zone". ExPASy. Retrieved 15 June 2015. ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 ... "Safety Study of Seneca Valley Virus in Patients With Solid Tumors With Neuroendocrine Features". "Seneca Valley Virus-001 After ...
Border disease virus Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 2 Classical swine fever virus Family: ... virus Uganda S virus Usutu virus Wesselsbron virus West Nile virus Yaounde virus Yellow fever virus Yokose virus Zika virus ... Bujaru virus Candiru virus Chilibre virus Frijoles virus Punta Toro virus Rift Valley fever virus Salehabad virus Sandfly fever ... virus Shuni virus Simbu virus Tacaiuma virus Tete virus Thimiri virus Timboteua virus Turlock virus Wyeomyia virus Zegla virus ...
Classical swine fever virus Cleome golden mosaic virus Cleome leaf crumple virus Clerodendron golden mosaic virus Clerodendron ... virus A Potato virus H Potato virus M Potato virus P Potato virus S Potato virus T Potato virus U Potato virus V Potato virus X ... virus Yam mild mosaic virus Yam mosaic virus Yam spherical virus Yam virus X Yambean mosaic virus Yaounde virus Yellow fever ... exanthema of swine virus Vibrio virus 493 Vibrio virus CTXphi Vibrio virus fs1 Vibrio virus fs2 Vibrio virus K139 Vibrio virus ...
Border disease virus Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 2 Classical swine fever virus Viruses in ... Pestivirus is a genus of viruses, in the family Flaviviridae. Viruses in the genus Pestivirus infect mammals, including members ... Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method ... ISBN 978-1-904455-22-6. The 7th ESVV Pestivirus Symposium-Uppsala, Sweden 2008 Animal viruses Virus Pathogen Database and ...
... feline immunodeficiency virus (FIV), tuberculosis, Texas cattle fever, classical swine fever (hog cholera), heartworm, and ... Virus-typing of polio by Salk "Archived copy". Archived from the original on 2008-09-05. Retrieved 2008-08-23. Salk polio virus ... In the 1940s, Jonas Salk used rhesus monkey studies to isolate the most virulent forms of the polio virus, which led to his ... Several of the bacterial viruses (bacteriophage) that infect E. coli also have been very useful for the study of gene structure ...
Feline immunodeficiency virus (FIV), tuberculosis, Texas cattle fever, Classical swine fever (hog cholera), Heartworm and other ... Virus-typing of polio by Salk [6] Salk polio virus [7] History of polio vaccine ""the work on [polio] prevention was long ... In the 1940s, Jonas Salk used rhesus monkey cross-contamination studies to isolate the three forms of the polio virus that ... Albert Sabin made a superior "live" vaccine by passing the polio virus through animal hosts, including monkeys. The vaccine was ...
... virus QI09AD03 Porcine reproductive and respiratory syndrome (PRRS) virus QI09AD04 Classical swine fever virus QI09AE01 ... porcine influenza virus QI09AA05 Porcine reproductive and respiratory syndrome (PRRS) virus QI09AA06 Classical swine fever ... QI09AA01 Aujeszky's disease virus QI09AA02 Porcine parvovirus QI09AA03 Porcine influenza virus QI09AA04 Aujeszky's disease ... erysipelothrix QI09AL04 Porcine influenza virus + erysipelothrix QI09AL05 Porcine transmissible gastro-enteritis virus + ...
African swine fever virus (ASFV) is a large double-stranded DNA virus which replicates in the cytoplasm of infected cells and ... They cause Classical swine fever (CSF) and Bovine viral diarrhea(BVD). Mucosal disease is a distinct, chronic persistent ... West Nile virus, Israel turkey meningoencephalomyelitis virus, Sitiawan virus, Wesselsbron virus, yellow fever virus and the ... Flaviviruses include the West Nile virus, dengue virus, Tick-borne Encephalitis Virus, Yellow Fever Virus, and several other ...
... then returned to Minnesota and studied classical swine fever (also known as hog cholera). Bachrach found that the disease could ... Bachrach was able to purify the virus responsible for foot-and-mouth disease. In 1950, having spent a year in Europe, Bachrach ... The other 90% of the specimen was "gunk" from the cells involved in the process of growing the virus, but no previous ... "Howard Bachrach, pioneer in fight against polio and other viruses". Star Tribune. July 25, 2008. Retrieved June 2, 2016. ...
... classical swine fever virus MeSH B04.909.777.411 --- hepatitis delta virus MeSH B04.909.777.415 --- hepatitis e virus MeSH ... diarrhea virus 2, bovine viral MeSH B04.820.250.700.400 --- classical swine fever virus MeSH B04.820.410.050 --- allolevivirus ... yellow fever virus MeSH B04.820.250.400 --- gb virus a MeSH B04.820.250.405 --- gb virus b MeSH B04.820.250.410 --- GB virus C ... rift valley fever virus MeSH B04.820.087.710.750 --- sandfly fever naples virus MeSH B04.820.087.710.900 --- uukuniemi virus ...
... disease is considered to be the most economically important viral disease of swine in areas where classical swine fever (hog ... The virus is shed in the saliva and nasal secretions of swine infected by the respiratory route. Aerosolization of the virus ... Swine (both domestic and feral) are usual reservoirs for this virus, though it does affect other species. Aujeszky's disease ... Diagnosis is made mainly by virus isolation in tissue cultures, or through ELISA or PCR tests. Vaccines are available for swine ...
... classical swine fever, avian influenza, Actinobacillus pleuropneumonia and Salmonella infections in pigs. Vaccine development ... The DIVA strategy has been applied in various countries and successfully eradicated pseudorabies virus. Swine populations were ... "Glycoprotein E1 of hog cholera virus expressed in insect cells protects swine from hog cholera". Journal of Virology. 67 (9): ... Examples include the subunit vaccine against Hepatitis B virus that is composed of only the surface proteins of the virus ( ...
Bluetongue virus (Exotic) Bovine spongiform encephalopathy Camel pox virus Classical swine fever virus Cowdria ruminantium ( ... African horse sickness virus African swine fever virus Akabane virus Avian influenza virus (highly pathogenic) ... Crimean-Congo haemorrhagic fever virus Diacetoxyscirpenol Ebola virus Lassa fever virus Marburg virus Monkeypox virus ... mouth disease virus Goat pox virus Japanese encephalitis virus Lumpy skin disease virus Malignant catarrhal fever virus ( ...
Some, like classical swine fever and scrapie are specific to one type of stock, while others, like foot-and-mouth disease ... This virus is easily transmissible to domestic poultry, and to humans living in close proximity with them. Other infectious ... "Classical swine fever" (PDF). The Center for Food Security and Public Health. Retrieved 20 May 2017. "Scrapie Fact Sheet". ... An outbreak of Nipah virus in Malaysia in 1999 was traced back to pigs becoming ill after contact with fruit-eating flying ...
This ancestor virus diverged about 1913-1915 into two clades (or biological groups), which gave rise to the classical swine and ... yellow fever, diphtheria, and cholera all occurred near the same time. These outbreaks probably lessened the significance of ... One hypothesis is that the virus strain originated at Fort Riley, Kansas, in viruses in poultry and swine which the fort bred ... Both the H2N2 and H3N2 pandemic strains contained avian flu virus RNA segments. "While the pandemic human influenza viruses of ...
African horse sickness virus African swine fever virus Avian influenza virus (highly pathogenic) Classical swine fever virus ... viruses: African VHF viruses: Crimean-Congo haemorrhagic fever virus Ebola virus* Lassa fever virus Lujo virus Marburg virus* ... Asian VHF viruses: Kyasanur Forest disease virus Omsk hemorrhagic fever virus South American VHF viruses: Chapare virus ... Hendra virus Nipah virus Rift Valley fever virus Venezuelan equine encephalitis virus (excluding enzootic subtypes ID and IE) ...
"Pathway analysis in blood cells of pigs infected with classical swine fever virus: comparison of pigs that develop a chronic ... Dynamics of virus excretion via different routes in pigs experimentally infected with classical swine fever virus strains of ... The Npro product of classical swine fever virus and bovine viral diarrhea virus uses a conserved mechanism to target interferon ... Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus ...
... Author(s). Smit, A.J. de; Bouma, A.; Terpstra, C.; ...
Classical swine fever virus (CSFV) is the causative agent of one of the most devastating porcine haemorrhagic viral diseases, ... Recent advances in the development of recombinant vaccines against classical swine fever virus: cellular responses also play a ... classical swine fever (CSF). CSFV mainly infects endothelial cells and macrophages and at the same time promotes bystander ... during which they either die or survive by producing neutralising antibodies to the virus. However, in a few cases, the ...
Reference Laboratory for classical swine fever offers one of the worlds largest semi-public virus-specific sequence ... The classical swine fever (CSF) DB (CSF-DB) became a valuable tool for supporting diagnosis and epidemiological investigations ... classical swine fever virus; sequence; database; disease control; classical swine fever ... Viruses 2016, 8, 302. AMA Style. Postel A, Schmeiser S, Zimmermann B, Becher P. The European Classical Swine Fever Virus ...
The virus is spread from infected or carrier pigs... ... 205) Swine fever is caused by one of the pesti family of ... viruses. The pig is the only natural host. ... Classical Swine Fever Virus (CSF) - Hog Cholera Virus (HC). See ... 205) Swine fever is caused by one of the pesti family of viruses. The pig is the only natural host. The virus is spread from ... When first introduced into the breeding herd it causes inappetence and high fevers. The virus can cross the placenta to invade ...
An Overview of the Immune Evasion Strategies Adopted by Different Viruses with Special Reference to Classical Swine Fever Virus ... 4. Few salient features about the disease Classical Swine Fever. Classical swine fever (CSF) is a disease of domestic pigs and ... An Overview of the Immune Evasion Strategies Adopted by Different Viruses with Special Reference to Classical Swine Fever Virus ... An Overview of the Immune Evasion Strategies Adopted by Different Viruses with Special Reference to Classical Swine Fever Virus ...
With classical swine fever virus (CSFV) commonplace in the world and barely outside the borders of North America, it is ... Development of classical swine fever virus diagnostic assays for porcine oral fluid samples. ... Possible use of a commercial blocking ELISA of classical swine fever antibody was also evaluated by using oral fluid samples ... Pilot study to develop ante-mortem synovial fluid and synovium sample collection techniques in growing swine and to refine a ...
The classical swine fever virus (CSFV) C-strain has been used as a vaccine strain for over 60 years in China. A recent study ... The role of noncoding regions of classical swine fever virus C-strain in its adaptation to the rabbit. Virus Res 183:117-122 ... The classical swine fever virus (CSFV) C-strain has been used as a vaccine strain for over 60 years in China. A recent study ... Chen N, Tong C, Li D, Wan J, Yuan X, Li X, Peng J, Fang W (2010) Antigenic analysis of classical swine fever virus E2 ...
Classical swine fever virus (CSFV), bovine viral diarrhea virus (BVDV), and border disease virus belong to the genus Pestivirus ... Virus-Cell Interactions. Inactivation of the RNase Activity of Glycoprotein Erns of Classical Swine Fever Virus Results in a ... RNase of classical swine fever virus: biochemical characterization and inhibition by virus-neutralizing monoclonal antibodies.J ... Classical swine fever virus: recovery of infectious viruses from cDNA constructs and generation of recombinant cytopathogenic ...
"Quasispecies composition and diversity do not reveal any predictors for chronic classical swine fever virus infection, Archives ... Passage of classical swine fever virus in cultured swine kidney cells selects virus variants that bind to heparan sulfate due ... Emergence of classical swine fever virus in Israel in 2009. David, D; Edri, N; Yakobson, BA; Bombarov, V; King, R; Davidson, I ... Genetic typing of classical swine fever virus. Paton, DJ; McGoldrick, A; Greiser-Wilke, I; Parchariyanon, S; Song, JY; Liou, PP ...
Pigs immunized with a novel E2 subunit vaccine are protected from subgenotype heterologous classical swine fever virus ... Classical swine fever (CSF) or hog cholera is a highly contagious swine viral disease. CSF endemic countries have to use ... However, it is impossible to serologically differentiate MLV vaccinated pigs from those infected with CSF virus (CSFV). The aim ... did not show any fever, had low or undetectable level of CSFV in blood and nasal fluid. At the time of CSFV challenge, only ...
Effectiveness of the E2-Classical Swine Fever Virus Recombinant Vaccine Produced and Formulated within Whey from Genetically ... Subunit recombinant vaccines against classical swine fever virus (CSFV) are a promising alternative to overcome practical and ... Effectiveness of the E2-Classical Swine Fever Virus Recombinant Vaccine Produced and Formulated within Whey from Genetically ... Effectiveness of the E2-Classical Swine Fever Virus Recombinant Vaccine Produced and Formulated within Whey from Genetically ...
Classical swine fever virus induces oxidative stress in swine umbilical vein endothelial cells. Overview of attention for ... Classical swine fever virus induces oxidative stress in swine umbilical vein endothelial cells ...
Classical swine fever virus (CSFV) E2 glycoprotein was expressed in an alphavirus based replicon expression system. Vaccinated ... Classical swine fever virus (CSFV) E2 glycoprotein was expressed in an alphavirus based replicon expression system. Vaccinated ... "Development of an Alphavirus Replicon Classical Swine Fever Virus Vaccine Candidate," Animal Industry Report: AS 659, ASL R2752 ...
Pestiviruses such as classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV) are some of the most ... Identification of cross-reactive epitope regions of bovine viral diarrhea virus and classical swine fever virus glycoproteins. ... Identification of cross-reactive epitope regions of bovine viral diarrhea virus and classical swine fever virus glycoproteins. ... Keywords: Immunology; Pestivirus; Epitope Mapping; Animal Diseases; Classical Swine Fever Virus; Bovine Viral Diarrhea Virus ...
Characterization of virus-specific T cell cytokine responses following vaccination and challenge with classical swine fever ... of virus-specific T cell cytokine responses following vaccination and challenge with classical swine fever viruses In: Annual ...
... caused by CSF virus (CSFV) is a highly contagious disease of the pigs. A number of studies have suggested that CSFV non- ... FKBP8 interact with classical swine fever virus NS5A protein and promote virus RNA replication. Virus Genes. 2016;52:99-106. ... Classical swine fever virus NS5A protein interacts with 3-untranslated region and regulates viral RNA synthesis. Virus Res. ... Classical swine fever (CSF) caused by CSF virus (CSFV) is a highly contagious disease of the pigs. A number of studies have ...
Existing live attenuated classical swine fever virus (CSFV) vaccines provide a rapid onset of complete protection but pose ... virus-specific peripheral blood cell cytokine responses following vaccination or infection with classical swine fever viruses. ... virus-specific peripheral blood cell cytokine responses following vaccination or infection with classical swine fever viruses. ... The results suggest that the C-strain virus is a potent inducer of a type-1 T cell response, which may play a role in the ...
The virus was highly contagious for the five pigs that were in direct contact with the inoculated pig, but spread to the other ... One pig in the middle pen of three adjacent pens was inoculated intramuscularly and intranasally with the virus. The fourth pen ... The first clinical signs observed after the virus was introduced into a pen were decreased feed intake, increased mean rectal ... The spread of the virus was promoted by contaminated clothing and footwear, but airborne transmission contributed considerably ...
... is a highly contagious fatal infectious disease caused by classical swine fever virus (CSFV). A better understanding of CSFV ... bovine viral diarrhea virus (BVDV), porcine parvovirus (PPV), porcine pseudorabies virus (PRV) and porcine circovirusII(PCV-2 ... With the development of novel RNA in situ Hybridization method, quantitatively localization and visualization of the virus RNA ... there was no cross-reaction with negative control and other viruses including BVDV, PPV, PRV and PCV-2. Our results showed that ...
Infection of target cells with various vaccinia virus/CSFV recombinants led to the identification of a major antigenic site for ... Their cytotoxic activity was determined against CSFV-infected target cells obtained from simian virus 40 (SV40) large T antigen ... Classical swine fever virus (CSFV) -specific cytotoxic T lymphocytes (CTL) were derived from peripheral blood mononuclear ... immortalized kidney cells of a syngeneic miniature swine. Experiments with separated effector cell populations revealed that ...
Classical swine fever virus Ab [Titer] in Serum by Neutralization test ... Name: Classical swine fever virus Ab [Presence] in Serum by Immunoassay System: Ser. Component: Classical swine fever virus Ab ... Name: Classical swine fever virus Ab [Titer] in Serum System: Ser. Component: Classical swine fever virus Ab. ... Classical swine fever virus Ab [Presence] in Serum by Neutralization test System: Ser. Component: Classical swine fever virus ...
E2 gene of classical swine fever virus (CSFV) was cloned into secretory pPIC9K Pichia pastoris expression vector. After being ... E2 gene of classical swine fever virus (CSFV) was cloned into secretory pPIC9K Pichia pastoris expression vector. After being ... The expression of classical swine fever virus structural protein E2 gene in tobacco chloroplasts for applying chloroplasts as ... Study on the expression of E2 gene of classical swine fever virus in Pichia pastoris and the immunological activity of its ...
Following CSFV challenge, the LPC-vaccinated pigs pre-inoculated with PCV2 showed transient fever, viremia, and viral shedding ... an attenuated strain of classical swine fever virus (CSFV), is an important tool for the prevention and control of CSFV ... Classical swine fever virus (CSFV) is an enveloped, positive sense, and single stranded RNA virus belonging to the genus ... Changes in the number of pigs developing fever in various treatment groups over time after classical swine fever virus (CSFV) ...
  • Pathway analysis in blood cells of pigs infected with classical swine fever virus: comparison of. (deepdyve.com)
  • Most animals experience acute infection, during which they either die or survive by producing neutralising antibodies to the virus. (nih.gov)
  • Laboratory tests include the identification of viral antigen, isolation of the virus and the presence of antibodies in serum. (thepigsite.com)
  • This effect could be neutralized by rescue of the inactivated E rns gene and by neutralizing polyclonal antibodies directed against E rns , indicating that this effect was an inherent property of the RNase-negative virus. (asm.org)
  • The immune response to PRRSV infection is characterized by a delayed appearance of neutralizing antibodies ( 31 ), a short cell-mediated immune response ( 34 , 59 ), and slow development of a virus-specific gamma interferon (IFN-γ) response ( 35 ). (asm.org)
  • Virus spread in various organs was followed by virus isolation, by immunohistochemistry, applying monoclonal antibodies in a two-step method and by in situ hybridisation using a digoxigenin-labelled riboprobe. (nih.gov)
  • This recognition leads to the expression of cytokines, chemokines and co-stimulatory molecules that eliminate pathogens like viruses for the activation of antigen presenting cells and for the activation of specific adaptive response [ 4 ]. (intechopen.com)
  • Swine leukocyte antigen (SLA) class I molecules play a crucial role in generating specific cellular immune responses against viruses and other intracellular pathogens. (frontiersin.org)
  • From PID 7 a higher amount of virus antigen was detected in the crypt-epithelial cells, migrating macrophages and lymphoid cells as well as in endothelial cells (Figure 2). (nih.gov)
  • Introductions of these viruses from humans and swine into southeast Mexico are indicated as groups of 8 horizontal lines, and each line represents 1 of 8 segments of the virus genome. (cdc.gov)
  • Pestiviruses are enveloped, plus-stranded RNA viruses whose genome comprises one long open reading frame ( 4 , 14 , 15 ). (asm.org)
  • The genome of positive-strand RNA viruses functions as mRNA from which all viral proteins necessary for virus propagation are translated. (pnas.org)
  • Pseudorabies virus (PRV) is a double-stranded, DNA-based swine virus with a genome approximating 150 kb in size. (hindawi.com)
  • The virus has a double-stranded linear DNA genome 1.43 × 10 5 kb in length [ 3 ] and contains a unique long region (UL), a unique short region (US), a terminal repeat sequence (TRS), and internal repeat sequences (IRS) [ 4 ]. (hindawi.com)
  • PRRSV is an enveloped, single-stranded RNA virus with positive-sense genome of ∼15 kb. (asm.org)
  • Pestiviruses are small, enveloped, positive-stranded RNA viruses ( 23 ). (asm.org)
  • Further studies are needed to detect and isolate the virus strains circulating in the country and understand the distribution and impact of pestiviruses in the Algerian livestock. (biomedcentral.com)
  • For pestiviruses and hepatitis C viruses (HCV), it has been reported that the 5′ NCR contains an internal ribosome entry site (IRES) for translation initiation ( 32 , 35 , 50 ). (asm.org)
  • Genus Tequatrovirus ( T4virus , T4-ähnliche Viren , en. (wikipedia.org)
  • All the identified virus isolates were classified as ASFV genotype I based on the partial B646L gene (C-terminal end of VP72 gene) and the full E183L gene encoding p54 protein analysis. (bioportfolio.com)
  • If the amino acid motif is similar to that observed for other HPAI isolates, then the isolate being tested should be considered HPAI and the virus is controlled for export. (ufl.edu)
  • Nyalugwe EP, Jones RAC, Barbetti MJ et al (2015) Biological and molecular variation amongst Australian turnip mosaic virus isolates. (springermedizin.de)
  • Hu X, He C, Xiao Y, Xiong X, Nie X (2009) Molecular characterization and detection of recombinant isolates of Potato virus Y from China. (springermedizin.de)
  • Scott, along with K-State researchers, led by Megan Niedwerder, a professor of diagnostic medicine and pathobiology, published the first report of classical swine fever virus and pseudorabies virus stability in feed ingredients. (hutchnews.com)
  • Niederwerder said both classical swine fever and pseudorabies virus can be found in areas of the world where feed ingredients are manufactured and imported into the U.S. (hutchnews.com)
  • Niederwerder said pseudorabies virus was detected in nine of the 12 tested ingredients: conventional and organic soybean meal, lysine, choline, vitamin D, moist cat and dog food, dry dog food, and pork sausage. (hutchnews.com)
  • The cowpox virus (CPV) complement inhibitor, termed inflammation modulatory protein (IMP), blocks immunopathological tissue damage at the site of infection, presumably by inhibiting production of the macrophage chemo attractant factors C3a and C5a. (intechopen.com)
  • Profiles of rectal temperature, viral RNA, E2 protein expression, and antibody responses were compared among the chimeric viruses. (springer.com)
  • The expression of classical swine fever virus structural protein E2 gene in tobacco chloroplasts for applying chloroplasts as bioreactors. (semanticscholar.org)
  • This NLS mediates the nuclear accumulation of MxA, whereas the swine Mx1 protein is not located inside nucleus for lack of NLS. (beds.ac.uk)
  • The ICA was also validated for the detection of PEDV in swine stool samples with little interference from swine stool. (springer.com)
  • To compare its accuracy to other traditional detection methods, 27 swine stool samples from south of China were investigated with the new developed ICA, commercial strip and RT-PCR. (springer.com)
  • The Classical Swine Fever (CSF) Surveillance Program is designed to enhance surveillance for the rapid detection of CSF virus introduced into U.S. swine by testing targeted swine populations in high risk states. (usda.gov)
  • A team led by Sachin Kumar of the Department of Biosciences and Bioengineering has been working on developing rapid detection and portable diagnostic kits for various viruses and microorganisms, the spokesperson said. (thehindu.com)
  • Gao F, Shen J, Shi F, Fang Z, Xie L, Zhan J (2013) Detection and molecular variation of Potato virus Y CP gene in China. (springermedizin.de)
  • Immunohistochemistry has the advantage to allow the rapid detection and localisation of the virus, especially in cases of early infection, when clinical signs are still absent. (nih.gov)
  • PRV has many nonessential genes which can be replaced with genes encoding heterologous antigens but without deleterious effects on virus propagation. (hindawi.com)
  • however, this subset of genes can be replaced by heterologous genes without affecting infectivity or virus propagation provided the essential genes remain intact. (hindawi.com)
  • Monocistronic mRNAs containing defective hepatitis C virus-like picornavirus internal ribosome entry site elements in their 5′ untranslated regions are efficiently translated in cells by a cap-dependent mechanism. (microbiologyresearch.org)
  • Identification of determinants involved in initiation of hepatitis C virus RNA synthesis by using intergenotypic replicase chimeras. (microbiologyresearch.org)
  • Hepatitis C virus (HCV) is now the most common cause of liver failure and liver transplantation in the United States and Europe. (asmscience.org)
  • Hepatitis C virus (HCV) is the most important cause of transfusion-associated and community-acquired non-A, non-B hepatitis ( 1 , 2 ). (pnas.org)
  • A contributor to Diseases of Swine, 8th edition, Dr. Zimmerman has selected three additional editors with international expertise. (wiley.com)
  • Topics include all priority livestock and aquaculture infectious diseases (including those caused by viruses, bacteria, pests, parasites) and non-infectious diseases. (bovinevetonline.com)
  • Classical swine fever is one of the diseases that will be studied at NBAF, and we're proud to be supporting progress in fighting this economic threat to pork production worldwide. (k-state.edu)
  • The range of clinical signs and its clinical similarity to other diseases can make classical swine fever challenging to diagnose. (usda.gov)
  • Tomlinson JA (1987) Epidemiology and control of virus diseases of vegetables. (springermedizin.de)
  • There are concerns that feed ingredients incorporated into swine diets may serve as new sources for the spread of animal diseases. (hutchnews.com)
  • Fig.2-4 illustrates the approximate survival times of viruses that cause pig diseases. (thepigsite.com)
  • This is why virus diseases are more common in winter than summer. (thepigsite.com)
  • But workers there also study more than 40 animal diseases, such as hog cholera and African swine fever, according to the government report. (courant.com)
  • The concept of this standardized and easy-to-use DB with an integrated genetic typing module is suited to serve as a blueprint for similar platforms for other human or animal viruses. (mdpi.com)
  • 2000. Genetic typing of classical swine fever virus . (invasivespeciesinfo.gov)
  • Nguyen HD, Tran HTN, Ohshima K (2013) Genetic variation of the Turnip mosaic virus population of Vietnam: a case study of founder, regional, and local influences. (springermedizin.de)
  • Ohshima K, Yamaguchi Y, Hirota R et al (2002) Molecular evolution of turnip mosaic virus: evidence of host adaptation, genetic recombination and geographical spread. (springermedizin.de)
  • Viruses contain a genetic code in the nucleic acid but they do not contain the full mechanisms for their own multiplication. (thepigsite.com)
  • You need info about Classical Swine Fever Virus Anitibody ELISA Kit or any other Gentaur produtct? (gentaurshop.com)
  • These processes are associated with the production of antigenic proteins that make the virus vulnerable to immune control mechanisms 'warning' the host of the presence of an invader [ 1 ]. (intechopen.com)
  • Viruses encode homologs of complement regulatory proteins that are secreted and block complement activation and neutralization of virus particles. (intechopen.com)
  • The Golgi apparatus and its resident proteins are utilized and regulated by viruses to facilitate their proliferation. (ias.ac.in)
  • They quickly loose their outer envelopes and the proteins covering their genes, which then take over from the cells nucleus and direct the cell to make more viruses. (thepigsite.com)
  • Human MxA has been shown to exhibit a wide antiviral capacity against small RNA viruses. (beds.ac.uk)
  • As the inherently wide antiviral capacity of MxA, we sought to generate a transgenic pig model that would express a high level of MxA under the control of the EF1a promoter to protect swine against CSF. (beds.ac.uk)
  • Proof of concept for this approach was obtained by an antiviral company, ViroVet, for classical swine fever virus. (thepigsite.com)
  • Feeding swine untreated food wastes containing infected pork scraps can cause infection, making raw garbage feeding a major risk for CSF incursion into swine herds. (usda.gov)
  • Niederwerder said reintroduction of these viruses into U.S. swine herds would be devastating. (hutchnews.com)
  • We've got very good data that the virus can come over from China or another ASF positive country, such as the Ukraine or Russia, and contaminate our swine herds here in the U.S.," Scott said. (hutchnews.com)
  • The database (DB) of the European Union (EU) and World Organisation for Animal Health (OIE) Reference Laboratory for classical swine fever offers one of the world's largest semi-public virus-specific sequence collections combined with a module for phylogenetic analysis. (mdpi.com)
  • However, the virus was not associated with any evident Italy-1/10-1 displayed the closest relatedness to atypical clinical signs. (cdc.gov)
  • Classical Swine Fever, although partly identical in name and clinical signs to African Swine Fever, is caused by a completely different virus than its namesake that is being found in increasingly more cases in China these days. (pigprogress.net)
  • Viruses such as classical swine fever disseminate throughout the body and damage different organs thus producing a variety of clinical signs. (thepigsite.com)
  • In addition to the IFN- responses, induction of both CD4+ T helper cell and CD8+ cytotoxic T cells (CTL) were discernible C activation of the latter was confirmed in a virus-specific cytolytic assay. (03964.com)
  • Die Entscheidung über verschiedene Taxa wird von einem internationalen Gremium, dem International Committee on Taxonomy of Viruses (ICTV), beraten und getroffen. (wikipedia.org)
  • King AM, Lefkowitz E, Adams MJ, Carstens EB (2012) Virus taxonomy, Ninth Report of the International Committee on Taxonomy of Viruses. (springermedizin.de)
  • Cryo EM structure of the rabies virus ribonucleoprotein complex. (nih.gov)