A species of the PESTIVIRUS genus causing exceedingly contagious and fatal hemorrhagic disease of swine.
An acute, highly contagious disease affecting swine of all ages and caused by the CLASSICAL SWINE FEVER VIRUS. It has a sudden onset with high morbidity and mortality.
The lone species of the genus Asfivirus. It infects domestic and wild pigs, warthogs, and bushpigs. Disease is endemic in domestic swine in many African countries and Sardinia. Soft ticks of the genus Ornithodoros are also infected and act as vectors.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
A sometimes fatal ASFIVIRUS infection of pigs, characterized by fever, cough, diarrhea, hemorrhagic lymph nodes, and edema of the gallbladder. It is transmitted between domestic swine by direct contact, ingestion of infected meat, or fomites, or mechanically by biting flies or soft ticks (genus Ornithodoros).
A genus of FLAVIVIRIDAE, also known as mucosal disease virus group, which is not arthropod-borne. Transmission is by direct and indirect contact, and by transplacental and congenital transmission. Species include BORDER DISEASE VIRUS, bovine viral diarrhea virus (DIARRHEA VIRUS, BOVINE VIRAL), and CLASSICAL SWINE FEVER VIRUS.
A species of PESTIVIRUS causing a congenital sheep disease characterized by an abnormally hairy birth-coat, tremors, and poor growth.
A family of large icosahedral DNA viruses infecting insects and poikilothermic vertebrates. Genera include IRIDOVIRUS; RANAVIRUS; Chloriridovirus; Megalocytivirus; and Lymphocystivirus.
Infections with viruses of the genus PESTIVIRUS, family FLAVIVIRIDAE.
The type species of the FLAVIVIRUS genus. Principal vector transmission to humans is by AEDES spp. mosquitoes.
Ribonucleic acid that makes up the genetic material of viruses.
Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.
A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.
A group of viruses in the genus PESTIVIRUS, causing diarrhea, fever, oral ulcerations, hemorrhagic syndrome, and various necrotic lesions among cattle and other domestic animals. The two species (genotypes), BVDV-1 and BVDV-2 , exhibit antigenic and pathological differences. The historical designation, BVDV, consisted of both (then unrecognized) genotypes.
Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.
A species of SWINE, in the family Suidae, comprising a number of subspecies including the domestic pig Sus scrofa domestica.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
A round-to-oval mass of lymphoid tissue embedded in the lateral wall of the PHARYNX. There is one on each side of the oropharynx in the fauces between the anterior and posterior pillars of the SOFT PALATE.
Established cell cultures that have the potential to propagate indefinitely.
Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
Proteins found in any species of virus.
Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). These do not include the proteins encoded in the VIRAL GENOME that are produced in infected cells but which are not packaged in the mature virus particle,i.e. the so called non-structural proteins (VIRAL NONSTRUCTURAL PROTEINS).
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Diseases of domestic swine and of the wild boar of the genus Sus.
Immunoglobulins produced in response to VIRAL ANTIGENS.
A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysosomal enzymes, changes in cell membrane permeability, diffuse changes in intracellular structures, presence of viral inclusion bodies, and chromosomal aberrations. It excludes malignant transformation, which is CELL TRANSFORMATION, VIRAL. Viral cytopathogenic effects provide a valuable method for identifying and classifying the infecting viruses.
Substances elaborated by viruses that have antigenic activity.
A species of NAIROVIRUS of the family BUNYAVIRIDAE. It is primarily transmitted by ticks and causes a severe, often fatal disease in humans.
An abnormal elevation of body temperature, usually as a result of a pathologic process.
Antibodies that reduce or abolish some biological activity of a soluble antigen or infectious agent, usually a virus.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.
The presence of viruses in the blood.
The complete genetic complement contained in a DNA or RNA molecule in a virus.
An acute infectious disease primarily of the tropics, caused by a virus and transmitted to man by mosquitoes of the genera Aedes and Haemagogus. The severe form is characterized by fever, HEMOLYTIC JAUNDICE, and renal damage.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity.
The interactions between a host and a pathogen, usually resulting in disease.
An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.
A genus of softbacked TICKS, in the family ARGASIDAE, serving as the vector of BORRELIA, causing RELAPSING FEVER, and of the AFRICAN SWINE FEVER VIRUS.
A subclass of PEPTIDE HYDROLASES that catalyze the internal cleavage of PEPTIDES or PROTEINS.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
A family of double-stranded DNA viruses containing one genus Asfivirus. It is the source of AFRICAN SWINE FEVER.
Animals considered to be wild or feral or not adapted for domestic use. It does not include wild animals in zoos for which ANIMALS, ZOO is available.

Localization of pestiviral envelope proteins E(rns) and E2 at the cell surface and on isolated particles. (1/236)

The glycoproteins E(rns) of classical swine fever virus (CSFV) and E(rns) and E2 of bovine viral diarrhoea virus (BVDV) are shown to be located at the surface of infected cells by the use of indirect immunofluorescence and by cytofluorometric analysis. The positive immunostaining of the cell surface was further analysed by immunogold electron microscopy and it could be shown that only extracellular virions were labelled. Gold granules were not seen at the cellular plasma membrane. In contrast to BVDV E2, the CSFV E2 of virions sticking to the plasma membrane was not accessible to the respective monoclonal antibodies. However, CSFV particles isolated from culture supernatant were able to bind both monoclonal anti-E(rns) and anti-E2 antibodies. For CSFV and BVDV, binding of anti-E(rns) antibodies to the virions was more pronounced than that of anti-E2. This finding was unexpected since E2 is considered to be the immunodominant glycoprotein.  (+info)

Cytopathogenic and noncytopathogenic RNA replicons of classical swine fever virus. (2/236)

To determine the minimal requirements for autonomous RNA replication of classical swine fever virus (CSFV), genomes having in-frame deletions within the genes for structural and flanking nonstructural proteins were constructed, based on an infectious cDNA clone of CSFV Alfort/187. RNA was transcribed in vitro from the respective plasmids and transfected into SK-6 swine kidney cells. The replication competence of the RNA was determined by immunostaining transfected cells for CSFV NS3 protein and by analysis of cell extracts for viral RNA, as well as protein synthesis at different times after transfection. The genes encoding N(pro), C, E(rns), E1, E2, p7, and NS2 proved to be dispensable for RNA replication, but the efficiency of replication varied strongly between individual constructs. RNA replicons containing the complete NS2-NS3 gene persisted in transfected cells and continued to replicate without causing any obvious morphological or functional damage to the cells, whereas genomes lacking the NS2 gene replicated more efficiently and induced a cytopathic effect. These findings suggest that NS2, although it is not essential for pestivirus RNA replication, has a regulatory function therein. Both cytopathogenic and noncytopathogenic replicons were packaged into virus particles provided in trans by a cotransfected full-length helper virus genome.  (+info)

Classical swine fever in Sardinia: epidemiology of recent outbreaks. (3/236)

A variable region of the gene encoding the major glycoprotein (E2) of Classical Swine Fever Virus (CSFV) was sequenced from 12 Sardinian isolates which had been obtained from three geographically distinct regions of the Island. Phylogenetic analysis of these viruses and others characterized in previous studies [1, 2] indicated that (a) the Sardinian viruses were all members of the common European subgroup 2.3 and were clearly distinct from live vaccines recently used in this area; (b) they could be resolved into four distinct groups in accordance with the region or date of isolation; (c) in at least two regions wild boar/domestic swine contact was implicated in virus spread; (d) the oldest isolate (1983) and some of the recent isolates were possibly introduced from mainland Italy. In addition, this study has wider implications for the interpretation of CSFV variation. We have been able to demonstrate that small variations within this region of the virus genome (possibly less than 2.7% or five nucleotide substitutions) can be used to separate isolates into groups that precisely fit their geographical distribution. This finding is especially important for deducing the epidemiological relationships between multiple outbreaks caused by similar viruses that occur in close proximity.  (+info)

Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation. (4/236)

Classical swine fever (CSF) is a severe hemorrhagic disease of swine caused by the pestivirus CSF virus (CSFV). Amino acid exchanges or deletions introduced by site-directed mutagenesis into the putative active site of the RNase residing in the glycoprotein E(rns) of CSFV abolished the enzymatic activity of this protein, as demonstrated with an RNase test suitable for detection of the enzymatic activity in crude cell extracts. Incorporation of the altered sequences into an infectious CSFV clone resulted in recovery of viable viruses upon RNA transfection, except for a variant displaying a deletion of the histidine codon at position 297 of the long open reading frame. These RNase-negative virus mutants displayed growth characteristics in tissue culture that were undistinguishable from wild-type virus and were stable for at least seven passages. In contrast to animals inoculated with an RNase-positive control virus, infection of piglets with an RNase-negative mutant containing a deletion of the histidine codon 346 of the open reading frame did not lead to CSF. Neither fever nor extended viremia could be detected. Animals infected with this mutant did not show decrease of peripheral B cells, a characteristic feature of CSF in swine. Animal experiments with four other mutants with either exchanges of codons 297 or 346 or double exchanges of both codons 297 and 346 showed that all these RNase-negative mutants were attenuated. All viruses with mutations affecting codon 346 were completely apathogenic, whereas those containing only changes of codon 297 consistently induced clinical symptoms for several days, followed by sudden recovery. Analyses of reisolated viruses gave no indication for the presence of revertants in the infected animals.  (+info)

The RNA-dependent RNA polymerases of different members of the family Flaviviridae exhibit similar properties in vitro. (5/236)

The virus-encoded RNA-dependent RNA polymerase (RdRp), which is required for replication of the positive-strand RNA genome, is a key enzyme of members of the virus family Flaviviridae. By using heterologously expressed proteins, we demonstrate that the 77 kDa NS5B protein of two pestiviruses, bovine viral diarrhoea virus and classical swine fever virus, and the 100 kDa NS5 protein of the West Nile flavivirus possess RdRp activity in vitro. As originally shown for the RdRp of hepatitis C virus, RNA synthesis catalysed by the pestivirus and flavivirus enzymes is strictly primer-dependent in vitro. Accordingly, initiation of RNA polymerization on homopolymeric RNAs and heteropolymeric templates, the latter with a blocked 3'-hydroxyl group, was found to be dependent on the presence of complementary oligonucleotide primer molecules. On unblocked heteropolymeric templates, including authentic viral RNAs, the RdRps were shown to initiate RNA synthesis via intramolecular priming at the 3'-hydroxyl group of the template and 'copy-back' transcription, thus yielding RNase-resistant hairpin molecules. Taken together, the RdRps of different members of the Flaviviridae were demonstrated to exhibit a common reactivity profile in vitro, typical of nucleic acid-polymerizing enzymes.  (+info)

Classical swine fever virus E(rns) deletion mutants: trans-complementation and potential use as nontransmissible, modified, live-attenuated marker vaccines. (6/236)

An SK6 cell line (SK6c26) which constitutively expressed the glycoprotein E(rns) of classical swine fever virus (CSFV) was used to rescue CSFV E(rns) deletion mutants based on the infectious copy of CSFV strain C. The biochemical properties of E(rns) from this cell line were indistinguishable from those of CSFV E(rns). Two E(rns) deletion mutants were constructed, virus Flc23 and virus Flc22. Virus Flc23 encoded only the utmost N- and C-terminal amino acids of E(rns) (deletion of 215 amino acids) to retain the original protease cleavage sites. Virus Flc22 is not recognized by a panel of E(rns) antibodies, due to a deletion of 66 amino acids in E(rns). The E(rns) deletion mutants Flc22 and Flc23 could be rescued in vitro only on the complementing SK6c26 cells. These rescued viruses could infect and replicate in SK6 cells but did not yield infectious virus. Virus neutralization by E(rns)-specific antibodies was similar for the wild-type virus and the recombinant viruses, indicating that E(rns) from SK6c26 cells was incorporated in the viral particles. Pigs vaccinated with Flc22 or Flc23 were protected against a challenge with a lethal dose of CSFV strain Brescia. This is the first demonstration of trans-complementation of defective pestivirus RNA with a pestiviral structural protein and opens new ways to develop nontransmissible modified live pestivirus vaccines. In addition, the absence of (the antigenic part of) E(rns) in the recombinant viral particles can be used to differentiate between infected and vaccinated animals.  (+info)

Pathogenesis of granulocytopenia and bone marrow atrophy during classical swine fever involves apoptosis and necrosis of uninfected cells. (7/236)

Granulocytopenia, a hematological hallmark of classical swine fever, is partially responsible for the suppression of innate immune defenses during classical swine fever. The present report demonstrates that this depletion was apparent as early as 3 days postinfection (p.i.). Both mature peripheral and bone marrow neutrophils were affected, whereas immature neutrophils increased absolutely in the periphery and coincidentally immature myeloid progenitors in the bone marrow. These data suggest that a pathogenic relationship exists between these compartments. The central event was not the arrest of hematopoietic cell proliferation or of the mobilization process, but instead apoptosis and possibly also necrosis were shown to play a role. This increase in apoptotic and dead cells was detected as early as 1-3 days p.i. In contrast, viral RNA in bone marrow hematopoietic cells (BMHC) was first detected 5 days p.i., and significant amounts of infected BMHC were detected only 7 days p.i., with the major target being the myeloid compartment. The increased caspase-3 activity observed supported a role for apoptotic cell death. Furthermore, the elevated caspase-9 activity indicated the involvement of the mitochondrial apoptotic pathway. Taken together, the results demonstrate that granulocytopenia and bone marrow atrophy are mediated by hematopoietic cell death and that indirect virus-host-mediated mechanisms are likely to be responsible.  (+info)

Ultrastructural glomerular changes in experimental infection with the classical swine fever virus. (8/236)

Ultrastructural studies of glomerular changes were performed on 16 pigs experimentally infected with a highly virulent strain of the classical swine fever virus. Our observations revealed the thickening of glomerular basement membranes, swelling of endothelial cells and cytoplasmic vacuolization within podocytes containing abundant viral particles. An early viral infection of podocytes was suggested as the cause of selective swelling of the foot processes of these cells with the consequent obliteration of the glomerular urinary spaces. To our knowledge this is the first report of ultrastructural evidence of classical swine fever virions infecting glomerular podocytes.  (+info)

Classical swine fever virus (CSFV) infection causes significant losses of pigs, which is characterized by hemorrhage, disseminated intravascular coagulation and leucopenia. The swine vascular endothelial cell is a primary target cell for CSFV. The aim of this study was to determine the role of CSFV infection in inducing oxidative stress (OS) in vascular endothelial cells. We demonstrated that CSFV infection induced oxidative stress in swine umbilical vein endothelial cells (SUVECs), characterized by the induction of reactive oxygen species (ROS) production and the elevations of porcine antioxidant proteins thioredoxin (Trx), peroxiredoxin-6 (PRDX-6) and heme oxygenase-1 (HO-1) expression. Furthermore, cyclooxygenase-2 (COX-2), a pro-inflammatory protein related to oxidative stress, was up-regulated while anti-inflammatory protein peroxisome proliferator-activated receptor-γ (PPAR-γ), an important mediator in vascular functional regulation, was down-regulated in the CSFV infected cells. In addition,
Graham, SP, Everett, HE, Haines, FJ, Johns, HL, Sosan, OA, Salguero, FJ, Clifford, DJ, Steinbach, F, Drew, TW and Crooke, HR (2012) Challenge of Pigs with Classical Swine Fever Viruses after C-Strain Vaccination Reveals Remarkably Rapid Protection and Insights into Early Immunity ...
Several emerging pestiviruses have been reported lately, some of which have proved to cause disease. Recently, a new ovine pestivirus (OVPV), isolated from aborted lambs, with high genetic identity to classical swine fever virus (CSFV), has proved to induce reproductive disorders in pregnant ewes. OVPV also generated strong serological and molecular cross‐reaction with CSFV. To assess the capacity of OVPV to infect swine, twelve piglets were infected either by intranasal or intramuscular route. Daily clinical evaluation and weekly samplings were performed to determine pathogenicity, viral replication and excretion and induction of immune response. Five weeks later, two pigs from each group were euthanized and tissue samples were collected to study viral replication and distribution. OVPV generated only mild clinical signs in the piglets, including wasting and polyarthritis. The virus was able to replicate, as shown by the RNA levels found in sera and swabs and persisted in tonsil for at least ...
Read Induction of immune responses in mice and pigs by oral administration of classical swine fever virus E2 protein expressed in rice calli, Archives of Virology on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Read Pathway analysis in blood cells of pigs infected with classical swine fever virus: comparison of pigs that develop a chronic form of infection or recover, Archives of Virology on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Classical swine fever (CSF) is a highly contagious swine disease caused by classical swine fever virus (CSFV). Previously, we demonstrated that rAdV-SFV-E2, an adenovirus-delivered, Semliki Forest virus replicon-vectored marker vaccine against CSF, is able to protect pigs against lethal CSFV challenge. From an economical point of view, it will be beneficial to reduce the minimum effective dose of the vaccine. This study was designed to test the adjuvant effects of Salmonella enteritidis-derived bacterial ghosts (BG) to enhance the protective immunity of rAdV-SFV-E2 in pigs. Groups of 5-week-old pigs (n = 4) were immunized intramuscularly twice with 105 median tissue culture infective doses (TCID50) rAdV-SFV-E2 combined with 1010 colony forming units (CFU) BG, 106 or 105 TCID50 rAdV-SFV-E2 alone or 1010 CFU BG alone at an interval of 3 weeks, and challenged with the highly virulent CSFV Shimen strain at 1 week post-booster immunization. The results show that the pigs inoculated with 105 TCID50 rAdV-SFV
Classical Swine Fever (CSF) is a serious and highly infectious viral disease of domestic pigs and wild boar (Paton and Greiser-Wilke 2003). The causative agent, Classical Swine Fever Virus (CSFV) is a small (40±60 nm) enveloped ribonucleic acid (RNA) virus with a single stranded genome with positive polarity (Horzinek et al. 1971; Moennig and Greiser-Wilke 2008). The virus is one of three pestiviruses that forms a group of economically important pathogens (Moennig et al. 1990) belonging to the Flaviviridae family. It has a close antigenic relationship with the other pestiviruses - bovine viral diarrhoea virus (BVDV) and border disease virus (BDV), as demonstrated by immunodiffusion and immunofluorescence tests, and their similar morphology and nucleic acid homology (Wengler 1991; Wengler et al. 1995). Indonesia was free from CSF until 1993. Between 1994 and 1996 thousands of pigs were reported to have died from the disease in the Indonesian regions of North Sumatera, Jakarta, Bali, Central ...
The early identification of classical swine fever epizootics is hampered by difficulties in recognising early signs of infection, due to a lack of specific clinical signs. In addition many textbook descriptions of CSF are based on observations of disease caused by historic, mainly genotype 1, strains. Our objective was to improve our knowledge of the diverse range of signs that different CSFV strains can cause by characterising the experimental infection of domestic pigs with both a recent strain of CSFV and a divergent strain. Conventional pigs were inoculated with a genotype 2.1 isolate, that caused an outbreak in the UK in 2000, and a genotype 3.3 strain that is genetically divergent from European strains. This latter strain is also antigenically distinct as it is only poorly recognised by the CSFV-specific monoclonal antibody, WH303. Transmission was monitored by use of in-contact animals. Clinical, virological and haematological parameters were observed and an extended macro- and ...
A surveillance program directed specifically at detecting Classical Swine Fever is now in progress at Iowa State University Veterinary Diagnostic Laboratory (ISU VDL). The ISU VDL is one of the 12 core laboratories in the National Animal Health Laboratory Network (NAHLN). The primary function of NAHLN labs is to participate in ongoing surveillance and response to foreign animal diseases and other events requiring an integrated laboratory effort of preparedness, controlled testing, and timely reporting. Federal funding for this program provides equipment and diagnostic reagents as well as support for technical positions and proficiency training of technicians. The ISU VDL has the in-house capability to test for Classical Swine Fever, High Pathogenic Avian Influenza and Exotic Newcastle Disease.. Diagnosticians at the ISU VDL will select suspect cases from routine submissions to the ISU VDL. The criteria listed below will be used in case selection.. ...
Classical swine fever virus (CSFV) -specific cytotoxic T lymphocytes (CTL) were derived from peripheral blood mononuclear leukocytes of immunized NIH-minipigs (MHC d/d haplotype) after in vitro restimulation with infectious CSFV. Their cytotoxic activity was determined against CSFV-infected target cells obtained from simian virus 40 (SV40) large T antigen-transfected immortalized kidney cells of a syngeneic miniature swine. Experiments with separated effector cell populations revealed that the CSFV-specific cytotoxic activity was mediated by CD4-CD6+CD8+ MHC class I-restricted T lymphocytes. Infection of target cells with various vaccinia virus/CSFV recombinants led to the identification of a major antigenic site for CSFV-specific CTL near the cleavage site between the non-structural proteins p80 (NS3) and p10 (NS4a). Using synthetic overlapping nonapeptides which covered this protein region the sequence ENALLVALF is the first sequence to be identified as an MHC class I-restricted T cell epitope
inproceedings{377967, author = {Dewulf, Jeroen and Laevens, Hans and KOENEN, F and Mintiens, Koen and de Kruif, Aart}, booktitle = {of the OIE International Conference on the Control of Infectious Animal Diseases by Vaccination}, title = {The use of conventional and marker vaccines in the control of classical swine fever epidemics}, year = {2004 ...
At his regular weekly round-up meeting with stakeholders, the Governments Chief Veterinary Officer, Jim Scudamore, emphasised the importance and reasons behind the current control measures against the outbreak of classical swine fever in East Anglia. Noting the recent reductions in the size of current infected areas, and the Commissions decision to limit the ban on exports of live pigs to Norfolk, Suffolk, and Essex, he said: Classical swine fever is a virulent disease which, once established, can be difficult to control.
Outbreaks of classical swine fever (CSF) can lead to large economic losses and have a major impact on animal welfare. A pig infected by CSF virus (CSFV) may show specific clinical symptoms (conjunctivitis, skin haemorrhages, cyanotic ears and lameness), but often the signs are aspecific (fever, dullness, diarrhoea and loss of appetite; Klinkenberg et al. 2005). Meanwhile, the infection can spread rapidly to other pigs (Laevens et al. 1998) and to other farms. At the moment the disease is first detected, a large number of farms may already be infected. To halt the epidemic, reducing the number of susceptible animals in the affected area is often required, especially in pig-dense regions. Two methods to achieve this are pre-emptive culling and emergency vaccination. Pre-emptive culling was used in the later stages of the 1997/1998 epidemic of CSF in The Netherlands, causing a large number of animals to be destroyed or prematurely slaughtered. This and subsequent experiences with foot-and-mouth ...
Zdravilo Porcilis Pesti so preučevali v okviru dveh terenskih študij varnosti, eni na pitancih in eni na svinjah, pri čemer sta bila uporabljena različna odmerka cepiva. Terenske študije potrjujejo rezultate laboratorijskih preizkusov varnosti in kažejo, da je izdelek varen za ciljne živali (pujski od 5 meseca dalje) in najobčutljivejšo kategorijo živali (breje svinje).. Glavno merilo učinkovitosti pri terenskih študijah s pujski je bilo preživetje pujskov, če so bili izpostavljeni virusu KPK pozneje v življenju. Pujski so bili testirani tudi za viremijo (prisotnost virusa v krvi). Začetek in trajanje imunosti so merili na podlagi protiteles proti antigenu (E2) virusa KPK, ki so jih tvorili pujski. Maternalno pridobljena protitelesa niso vplivala na rezultate cepljenja.. ...
Classical Swine Fever (CSF) is an endemic disease in Cuba, and an eradication strategy by zones is planned by the Official Veterinary Service. The aim of this study was to identify high-risk areas of CSF and the risk factors associated with the disease occurrence in the Pinar del Río province, one of the prioritized areas in the eradication strategy. The outbreak occurrence at district level was analyzed through a 7-year period (2009 to 2015). A high-risk cluster (RR = 5.13, 95% CI 3.49-7.56) was detected during the last 2 years of the study period in the eastern half of the province, with 38 out of 97 districts included. The rate of CSF-affected holdings had a significant increase during 2014-2015 and seems to have occurred mainly in the high-risk cluster area. Swine population density by district (heads/km2) and road length (km) by district were associated with the disease outbreak occurrence. These results provide new insights into the knowledge of the epidemiology of the disease in Cuban endemic
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Accepted name: pestivirus NS3 polyprotein peptidase. Reaction: Leu is conserved at position P1 for all four cleavage sites. Alanine is found at position P1 of the NS4A-NS4B cleavage site, whereas serine is found at position P1 of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites. Other name(s): border disease virus NS3 endopeptidase; BDV NS3 endopeptidase; bovine viral diarrhea virus NS3 endopeptidase; BVDV NS3 endopeptidase; classical swine fever virus NS3 endopeptidase; CSFV NS3 endopeptidase; p80. Comments: The polyprotein of noncytopathogenic pestiviruses is cleaved co- and post-translationally into at least 11 proteins (Npro, C, Erns, E1, E2, p7, NS2-3, NS4A, NS4B, NS5A, and NS5B) [2]. The genomes of cytopathogenic pestivirus strains express at least one additional protein, called NS3 (p80) [2]. This enzyme, which resides in the N-terminal region of NS3 (nonstructural protein 3), is essential for generation of its own C-terminus and for processing of the downstream cleavage sites, ...
The present study investigated the transcriptomic response of porcine dendritic cells (DC) to innate stimulation in vitro and in vivo. The aim was to identify DC subset-specialization, suitable Toll-like receptor (TLR) ligands targeting plasmacytoid DC (pDC), and the DC activation profile during highly and low virulent classical swine fever virus (CSFV, strain Eystrup and Pinar del Rio, respectively) infection, chosen as model for a virus causing a severe immunopathology. After identification of porcine conventional DC (cDC) 1, cDC2, pDC and a monocyte-derived subset in lymphoid tissues, we characterized DC activation using transcriptomics, and focused on chemokines, interferons, cytokines, as well as on co-stimulatory and inhibitory molecules. We demonstrate that porcine pDC provide important signals for Th1 and interferon responses, with CpG triggering the strongest responses in pDC. DC isolated early after infection of pigs with either of the two CSFV strains showed prominent upregulation of CCL5,
2008) Classical swine fever virus vaccine stability in Lao PDR. In: Conlan, J., Blacksell, S., Morrissy, C. and Colling, A., (eds.) Management of classical swine fever and foot-and-mouth disease in Lao PDR : proceedings of an international workshop held in Vientiane, Lao PDR, 20-21 November 2006. ACIAR Proceedings No. 128. ACIAR, Canberra, Australia, pp. 80-83. Morrissy, C., Wright, L., Conlan, J., Goff, W., Colling, A., Hammond, J., Johnson, M., Blacksell, S. and Daniels, P. ...
Marie-Frédérique; Neyts, Johan; F. Koenen Source: J Gen Virol, Volume 90, Issue Pt 6, p.1335-42 (2009) Keywords: Administration, Oral Animals Antiviral Agents Classical Swine Fever Classical swine fever virus .... ...
hybridization patterns, the distinct genotypes of CSFV Brecent years. It can detect different pathogens in a could be differentiated. The results showed that the piece of chip and can differentiate the various CSFV amplified by primer CP5.6 could be classified into genotypes in the same species. In 2003, a bio-chip three genotypes, including the native, invaded, and diagnosis system was established by using classical lapinized hog cholera vaccine virus by hybridization swine fever virus (CSFV) as a model. Nucleotide with oligonucleotide probe. No cross reaction was sequences of classical swine fever virus were collected found when the bio-chip was hybridized with bovine from the GenBank, and the domestic CSFV field strains diarrhea disease virus which was closely related to the were sequenced. These sequence data were analyzed with a computer software by sequence alignment and apair of universal primers, which could amplify different News source: National Veterinary Research Insti- ...
Experimental vaccine prototypes against: Porcine Respiratory and Reproductive Syndrome Virus, porcine circovirus type 2, classical swine fever virus, African swine fever virus, porcine and avian influenza Viruses, foot-and-mouth disease virus, Haemophilus parasuis, Mycobacterium spp, Gumboro, Rift Valley fever virus and many others ...
Baroness Hayman today attended a meeting between senior MAFF officials and representatives of all industries affected by the CSF outbreak. The Minister of State had been invited to the meeting at Harleston, Norfolk, which provided a further opportunity to discuss face-to-face with those affected the practical welfare and financial problems being experienced in infected areas. Speaking after the meeting Baroness Hayman said: Classical swine fever is a highly contagious pig disease which can have a devastating impact on businesses and families, whether through the disease itself or consequential movement restrictions. I have come to East Anglia again today to listen directly to those affected by this outbreak. A variety of issues were raised which will be considered both at the control centre in Bury St Edmunds and in London. Controlling this disease remains of paramount importance to farmers and the wider industry. It is our first priority. We have been aware for some time of the potential welfare
The objective of this study was to describe oral fluid and serum antibody (IgG, IgA) responses against classical swine fever virus (CSFV) E2 and Erns proteins in pigs (n = 60) inoculated with a moderately virulent field strain (ALD, n = 30) or a modified live virus vaccine strain (LOM, n = 30). Oral fluid (n = 1391) and serum (n = 591) samples were collected from individually-housed pigs between d ...
Genetic labelling of viruses with a fluorophore allows to study their life cycle in real time, without the need for fixation or staining techniques. Within the family Flaviviridae, options for genetic labelling of non-structural proteins exist. Yet, no system to genetically label structural proteins has been put forward to date. Taking advantage of a previously described site within the structural protein E2, a fluorophore was introduced into a cytopathogenic (cpe) BVDV-1 virus (BVDVE2_fluo). This insertion was well tolerated, resulting in a 2-fold drop in titer compared to the parental virus, and remained stably integrated into the genome for more than 10 passages. The fluorophore E2 fusion protein was readily detectable in purified virus particles by Western blot and fluorescence microscopy and the particle integrity and morphology was confirmed by cryo electron microscopy. The same integration site could also be used to label the related Classical swine fever virus. Also, BVDVE2_fluo particles bound
No diagnostic sample submission is complete without including the tonsil. Because of their location in the oropharynx, the tonsils are exposed to a variety of viral and bacterial pathogens. Advances in diagnostic capabilities have made analysis of the tonsils an increasingly important tool in diagnosing a number of endemic swine diseases. United States Department of Agriculture (USDA) Animal and Plant Health Inspection Services (APHIS) now has funding to use the tonsil as part of a routine surveillance program to detect classical swine fever (CSF) and is offering incentives to encourage practitioners to submit samples for surveillance.. Tests using the tonsil have been developed by the Foreign Animal Disease Diagnostic Laboratory (FADDL) at USDAs Plum Island Animal Disease Center to aid in detection and diagnosis of CSF. USDAs Classical Swine Fever (CSF) Surveillance Procedure Manual1 includes tonsil, tonsil scrapings, and nasal swabs as appropriate samples for CSF detection if collected and ...
This video covers vaccines and diagnostic tests for avian influenza and is designed for those who will select vaccines and diagnostic tests to be used in an H5N1 avian influenza control program ...
Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Veterinary Manual was first published in 1955 as a service to the community. The legacy of this great resource continues as the Merck Veterinary Manual in the US and Canada and the MSD Manual outside of North America.. ...
TY - ABST. T1 - Virulence in pigs of vPader10 rescued from an infectious cDNA clone of the CSFV strain Paderborn. AU - Friis,Martin Barfred. AU - Nielsen,Jens. AU - Uttenthal,Åse. AU - Belsham,Graham. AU - Rasmussen,Thomas Bruun. PY - 2012. Y1 - 2012. N2 - The BAC clone, pBeloPader10, contains a complete cDNA of the CSFV strain Paderborn. Virus, named vPader10, was rescued from this construct by electroporation of RNA transcripts into porcine PK15 cells. To further study the characteristics of vPader10, we evaluated the virulence of this virus in vivo in pigs. An animal experiment was performed where three pigs were inoculated with vPader10 and housed in-contact with two non-inoculated pigs for 5 weeks. Following inoculation with vPader10, two out of three pigs displayed severe clinical signs of CSF from PID 14 that progressed until death of the pigs at PID 21 and PID 22, respectively. High fever (,41ºC) was observed in these pigs from PID 14 and remained at a high level until day of death. ...
Classical swine fever is currently not only a problem in certain regions of Germany but also in the Eastern Cape region. An outbreak means severe economical problems. The Eastern Cape agriculture authorities even admitted that they don`t know whether they are winning the fight against swine fever.
5 September 2000 New case of swine fever in Suffolk By FWi staff A FURTHER case of classical swine fever has been confirmed on a farm in the surveillance a
The domestic swine fever virus C strain was purified by USA, Japan, local swine fever, but the domestic swine fever epidemic is still serious. Control of classical swine fever, the industry has different views, many people think is the prob
Economics of classical swine fever - CSF - hog cholera - movement ban controls on UK pig farms in protection and surveillance zones.
It is unknown how widespread the new Linda virus is in the swine population. We are currently developing a serological test to learn more about the prevalence of the Linda virus in Austria, i.e. about the number of piglets it infects, says Lamp. The test will be important because analysis of the virus has shown that it is distantly related to the virus that causes classical swine fever. We cannot exclude the possibility that it might interfere with the official tests for swine fever. In addition, it is unclear how much of a danger the newly discovered virus poses for pig breeding. The Spanish word linda is usually translated as pretty or cute but there is nothing pretty or cute about the newly discovered Linda virus. Till Rümenapf, the Head of the Institute, notes that Because it also infects the uterus of pregnant sows, the Linda virus could disrupt the development of the piglets cerebral cortex, like infection with the Zika virus. However, we should remember that the closest ...
First report focuses on African swine fever, foot-and-mouth disease and classical swine fever as the near real-time monitoring system is developed and tested.
Overall 137 programmes have been selected for EU funding to tackle animal diseases that impact on human and animal health as well as trade. The elected programmes were granted the following allocation: Bovine Tuberculosis (about €71 million); Transmissible Spongiform Encephalopathies (about €54 million); Bovine Brucellosis (about €7.4 million), rabies (€25 million); Bluetongue (€1.5 million); Classical Swine Fever (€2.5 million); Salmonellosis (about €16.6 million); Avian influenza (€2.6 million) and African Swine Fever in Sardinia (€1.4 million ...
AUSTRIA - Some newly born piglets shiver even when they are kept warm. So-called "shaking piglets" have symptoms that resemble those of the classical swine fever, with extensive damage to the brain and the spinal cord.
Marie-Frédérique Source: Front Microbiol, Volume 6, p.1141 (2015) Abstract: Classical swine fever (CSF) is among the most detrimental diseases for the swine industry worldwide. Infected wild boar populations can .... ...
TY - CONF. T1 - New and emerging technologies: Improved laboratory and on-site detection of OIE List A viruses in animals and animal products. AU - Belak, Sandor. AU - Uttenthal, Åse. AU - Hakhverdyan, Mikhayil. AU - Allan, Gordon. AU - Sanchez-Vizcaino, Jose Manuel. AU - Istvan, Kiss. AU - Merza, Malik. AU - Brocchi, Emiliana. AU - van Reeth, Kristien. AU - King, Donald. PY - 2008. Y1 - 2008. KW - Classical swine fever. KW - Foot and Mouth Disease. KW - Virus. KW - OIE listed diseases. M3 - Poster. T2 - 2nd Annual Meeting EPIZONE. Y2 - 4 June 2008 through 6 June 2008. ER - ...
Alamian S, Amiry K, Bahreinipour A, Etemadi A, Tebianian M, Mehrabadi MHF and Dadar M (2021) Brucella species circulating in rural and periurban dairy cattle farms: a comparative study in an endemic area. Tropical Animal Health and Production 53:200. doi:10.1007/s11250-021-02645-y.. Amarir F, Rhalem A, Sadak A, Raes M, Oukessou M, Saadi A, Bouslikhane M, Gauci CG, Lightowlers MW, Kirschvink N and Marcotty T (2021) Control of cystic echinococcosis in the Middle Atlas, Morocco: Field evaluation of the EG95 vaccine in sheep and cesticide treatment in dogs. PLoS Neglected Tropical Diseases 15:e0009253. doi:10.1371/journal.pntd.0009253.. Bazarragchaa E, Isoda N, Kim T, Tetsuo M, Ito S, Matsuno K and Sakoda Y (2021) Efficacy of oral vaccine against classical swine fever in wild boar and estimation of the dsease dynamics in the quantitative approach. Viruses 13. doi:10.3390/v13020319.. Bertran K, Kassa A, Criado MF, Nuñez IA, Lee DH, Killmaster L, Sá E Silva M, Ross TM, Mebatsion T, Pritchard N and ...
Dr. Dilip Kumar Sarma received his B.V.Sc &A.H. Degree from Assam Agricultural University in 1978 securing first class first position. He did his M.V.Sc and Ph.D degrees in Veterinary Bacteriology and Virology from Punjab Agricultural University, Ludhiana, India in 1981 and 1987 respectively. He had one year post doctoral research training at the AFRC Institute for Animal Health, Pirbright Laboratory, Surrey, U.K. under Commonwealth Govt. Scholarship. He has worked as Lecturer, Asstt. Professor, Virologist and as a Professor in the Department of Microbiology, Assam Agricultural University, Khanapara, Guwahati, since 2004. He has received the National Fellow Award of the Indian Council of Agricultural Research, New Delhi, India to work in a project on Classical swine fever and he has been working in the project since 2005. He has guided four Ph.D students, published two textbooks and 165 research papers in the National and International Journals and several popular scientific articles. He has ...
At least 210 pigs and piglets have died due to outbreak of classical swine flu in Mizoram-Myanmar border Champhai town and Biate village in Champhai
Hog Cholera (Classical Swine Fever). Sandra Axiak and Carolin Winter. Definition of hog cholera:. highly contagious viral disease of swine can cause acute, chronic, or congenital disease considered a foreign animal disease. Foreign animal disease (FAD):. Definition: Slideshow 113381 by flora
Virions from hog cholera virus (HCV), a member of the genus Pestivirus, were analyzed by using specific antibodies. The nucleocapsid protein was found to be a 14-kDa molecule (HCV p14). An equivalent protein could also be demonstrated for virions from another pestivirus, bovine viral diarrhea virus. The HCV envelope is composed of three glycoproteins, HCV gp44/48, gp33, and gp55. All three exist in the form of disulfide-linked dimers in virus-infected cells and in virions; HCV gp44/48 and gp55 each form homodimers, whereas gp55 is also found dimerized with gp33. Such complex covalent interactions between structural glycoproteins have not been described so far for any RNA virus. ...
Background The genus pestivirus within the family Flaviviridaeincludes bovine viral diarrhoea virus (BVDV) types 1 and 2, border disease virus (BDV) and classical swine fever virus. The two...
Wang, L., S. Mi, R. Madera, L. Ganges, M.V. Borca, J. Ren; C. Cunningham, A.G. Cino-Ozuna, H. Li, C. Tu, W. Gong; and J. Shi. 2020. A neutralizing monoclonal antibody-based competitive ELISA for classical swine fever C-strain post-vaccination monitoring. BMC Veterinary Research. Open Access. https://link.springer.com/article/10.1186/s12917-020-2237-6. Borca, M.V., V. ODonnell, L.G. Holinka, G.R. Risatti, E. Ramirez-Medina, E.A. Vuono, J. Shi, S. Pruitt, A. Rai, E. Silva, L. Velazquez Salinas, and D.P. Gladue. 2020. Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine. Scientific Reports. 10:494.. Evans, T.S., Z. Shi, M. Boots, W. Liu, K. Olival, X. Xiao, S. Vandewoude, H. Brown, J. Chen, D. Civitello, L. Escobar, Y. Grohn, H. Li, K. Lips, Q. Liu, J. Lu, B. Martinez-Lopez, J. Shi, X. Shi, B. Xu, L. Yuan, G. Zhu, and W. Getz. 2020. Synergistic China-US Ecological Research is Essential for Global EID Preparedness. EcoHealth. ...
occurs in South America, Asia (including Indonesia) and certain European countries. Information on current country status can be obtained from the OIE World Animal Health Information Database. The last time CSF occurred in Australia was in 1962. Outbreaks have recently been reported in Bulgaria (in wild species), Israel and Lithuania.. Classical swine fever virus is a highly contagious Pestivirus which only infects swine, and is antigenically related to border disease virus and bovine viral diarrhoea virus. Pig to pig transmission is most common but CSF can also be spread by aerosol, swill feeding and mechanically by insects and fomites. Swill feeding of peri-urban pigs is a likely method of re-introduction of this virus to Australia and hence CSF may first be encountered by a veterinary practitioner servicing these areas. Strains vary greatly in their virulence. The last outbreak in Australia was caused by a mild strain that was detected only by a reported increase in fevered carcasses at ...
In 2016, two small-scale fattening pig farms (about 200 or 300 American Landrace pigs in total), locating in Guangdong province (southern China) and Jilin province (northern China) separated by more than 3, 000 km in distance (Fig. 1), suffered from severe respiratory disease (SRD). Pigs (2-3 months old) on both farms have received immunizations against PCV2, pseudorabies virus (PRV), classical swine fever virus (CSFV) and type 2 porcine reproductive and respiratory syndrome virus (PRRSV). However, the morbidity rate of pigs on the two farms was approximately 60%, the mortality in affected pigs was about 80%. From autopsy results of 18 individual dead pigs (n = 8 for farm A, n = 10 for farm B) (Additional file 1: Table S1), the similar macroscopic lesions were concentrated in the lungs and lymph nodes, which was characterized by PRRSV- or PCV2-like lesions including pulmonary interstitial widening, congestion and lymphadenopathy bleeding. These 18 pig lung samples were defined as the samples ...
APHIS recognizes the prevalence of CSF in Guatemala and responded immediately to their request for assistance to help control their latest outbreak, said Dr. John R. Clifford, USDAs Chief Veterinary Officer. We sent a team of subject matter experts to assess the situation and concluded that the use of much-needed vaccine would help in containing the spread of the disease.. On March 19, APHIS donated the vaccines based on a request for assistance from the Guatemalan Chief Veterinary Officer, Dr. Humberto Maldonado, to help Guatemala control the spread of CSF there.. This assistance will help control and limit spread of CSF in Guatemala and neighboring countries. Among these countries are Mexico, currently working to control and eradicate the disease, and the United States, which has been free of CSF for over 30 years. Thus, this assistance extends beyond Guatemala and contributes to safeguarding animal health throughout Central and North America.. With trade opportunities increasing each ...
swine fever virus N(pro) protein: has autoproteolytic activity; inhibits double-stranded RNA-mediated apoptosis and IFN-alpha/beta induction; GenBank AF144472
Exotic animal diseases (EADs) are characterized by their capacity to spread global distances, causing impacts on animal health and welfare with significant economic consequences. We offer a critique of current import risk analysis approaches employed in the EAD field, focusing on their capacity to assess complex systems at a policy level. To address the shortcomings identified, we propose a novel method providing a systematic analysis of the likelihood of a disease incursion, developed by reference to the multibarrier system employed for the United Kingdom. We apply the network model to a policy-level risk assessment of classical swine fever (CSF), a notifiable animal disease caused by the CSF virus. In doing so, we document and discuss a sequence of analyses that describe system vulnerabilities and reveal the critical control points (CCPs) for intervention, reducing the likelihood of U.K. pig herds being exposed to the CSF virus. ...
How BVDV affects fetal development depends on the timing of maternal infection during pregnancy. The eyes and central nervous system are targets of the virus, and characteristic deformations of the brain and skull are observed. These deformities include hydranencephaly, hydrocephalus, and microencephaly [6].. BVDV is not transmissible to people but can infect a number of ruminants. Other species in the pestivirus family - siblings to bovine viral diarrhea - include border disease of sheep and classical swine fever in pigs. All of these pestiviruses can cause birth deformities.. Another fascinating aspect of pestiviruses is that they can affect host immunity during infection. BVDV is capable of becoming a persistent infection that is never fully cleared from the body. Persistent infection can happen in a number of ways. BVDV can manipulate the mechanisms that identify pathogens in the body. The virus is therefore camouflaged as self and avoids targeting by the immune system [7]. Calves may be ...
Imports of pork rinds, a snack food made from deep-fried pork skins, are so well cooked that the risk of transmitting hog diseases, such as foot-and-mouth disease, swine vesicular disease, African swine fever and classical swine fever, is non-existent, said the U.S. Department of Agriculture's Animal and Plant Health Inspection Service.
The European Commission said that given the serious impact that animal disease outbreaks can have on human health, society, the economy and trade, the allocation of EU co-financing will continue to assist national authorities to put in place precautionary measures, disease surveillance and eradication programmes, at national and European level.. Overall 142 programmes have been selected for EU funding: Bovine Tuberculosis (about €56 million); Transmissible Spongiform Encephalopathies (about €42 million); Rabies (€27.5 million); Salmonellosis (about €17.5 million); Bovine Brucellosis (about €10 million); Classical Swine Fever (€3 million); Avian Influenza (€2.5 million); Bluetongue (€1.5 million); African Swine Fever and Swine Vesicular Disease in Italy (about €850.000).. EU co-financing has resulted in a continuous decrease in the number of cases of diseases, such as Salmonellosis (the second most frequently reported zoonotic disease in humans) and Transmissible Spongiform ...
Bovine Viral Diarrhoea (BVD) is a highly contagious viral disease of cattle. It is one of the most costly cattle diseases in the world, causing a variety of illnesses that can result in death. This animation describes the problem that farmers face in the battle against BVD, and what preventative measures can be taken to combat it.. Bovine viral diarrhoea (BVD) is closely related to the viruses that cause classical swine fever in pigs and border disease in sheep. The disease is widespread around the world and has a major economic impact in the cattle industry. Estimated losses in a beef herd can be as much as £45,000 over a ten year period while these losses are even higher in Dairy herds!. Infection in pregnant animals can result in abortion, the birth of stunted or deformed calves and calves born with persistent infection (PI). Infection during the first third of pregnancy can compromise the development of the foetal immune system and the calf is unable to eliminate the virus. PIs often ...
Romania will be resuming on-farm vaccinations against classical swine fever (CSF) soon, the website of the US Department of Agriculture says.
At the IVMR, a rich past and an intense present complement each other. József Csontos (1889-1962), founding director of the then-called Animal Health Research Institute, together with Aladár Aujeszky developed the so-called carbolic glycerinated vaccine against rabies containing fixed virus. After World War II, he played a pivotal role in the eradication of infectious animal diseases, above all classical swine fever and porcine erysipelas, and also took part in organizing the healthcare of large stocks in intensive animal farming. Among past researchers of the institute, one of worldwide fame was Domokos Derzsy (1914-1975), whose scientific topics of interest spanned almost the entire spectrum of infectious animal diseases. He diagnosed and described several poultry diseases unknown in Hungary before, one of these was that caused by goose Parvovirus, which was named Derzsys disease in honor of his internationally significant research on this pathogen. Adorján Bartha (1923-1996) also worked ...
At the IVMR, a rich past and an intense present complement each other. József Csontos (1889-1962), founding director of the then-called Animal Health Research Institute, together with Aladár Aujeszky developed the so-called carbolic glycerinated vaccine against rabies containing fixed virus. After World War II, he played a pivotal role in the eradication of infectious animal diseases, above all classical swine fever and porcine erysipelas, and also took part in organizing the healthcare of large stocks in intensive animal farming. Among past researchers of the institute, one of worldwide fame was Domokos Derzsy (1914-1975), whose scientific topics of interest spanned almost the entire spectrum of infectious animal diseases. He diagnosed and described several poultry diseases unknown in Hungary before, one of these was that caused by goose Parvovirus, which was named Derzsys disease in honor of his internationally significant research on this pathogen. Adorján Bartha (1923-1996) also worked ...
Outbreaks of notifiable infectious animal diseases, such as foot-and-mouth disease, classical swine fever and avian influenza, have major societal and economic consequences. Fortunately, such animal diseases occur infrequently in the Netherlands. Wageningen Bioveterinary Research (WBVR) contributes to this status by designing risk-based surveillance systems.
26 September 2000 Unigate blames losses on swine fever UNIGATE has blamed the outbreak of swine fever for preventing its pork processing plant in North Yor
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Countries across Asia are struggling to contain an outbreak of swine fever, which is threatening the livelihoods of millions of families that rely on pig farming. The highly contagious and incurable virus is deadly to pigs but not dangerous to humans. The disease originally spread from Africa
Another case of swine fever was detected in Manta in Cahul district. The virus was confirmed by laboratory analysis after a man announced to the National Agency for Food Safety in the district that he had found his pig dead.Immediately, the emergency comm
Global price cycle, Swine Fever outbreak in S Korea, China bans Dutch food imports, USDA forecasts, EU vets vote for new Spanish and German CSF measures, UK farmers suffer second FMD scare.....
Sigma-Aldrich offers abstracts and full-text articles by [Jiangnan Li, Yajuan Dai, Shuai Liu, Huancheng Guo, Tiedong Wang, Hongsheng Ouyang, Changchun Tu].
In der medizinischen Versorgung bekommt die Ernährung einen immer größeren Stellenwert. Zum einen sind heute Nahrungsmittelunverträglichkeiten häufiger anzutreffen, andererseits wird eine Ernährungsth
"U18666A inhibits classical swine fever virus replication through interference with intracellular cholesterol trafficking". ... Finally, SNX8 also plays an antiviral role against RNA viruses such as SeV (Sendai virus) through VISA-mediated activation of ... In addition, SNX8 plays an antiviral role against DNA viruses such as HSV-1 through the MITA-mediated activation of the IFNβ ... SNX8 is a key component in the induction of downstream effector antiviral gene transcription in response to RNA viruses, as it ...
"Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ...
The classical swine fever virus UTR described appears to be longer at the 5' end than other pestivirus UTRs. This family ... "Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ...
"Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ...
"Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA. 6 (12): 1791-1807. doi:10.1017/ ... nontranslated region of hepatitis A virus RNA: comparison with the IRES of encephalomyocarditis virus". Journal of Virology. 68 ... For influenza A virus, its primary method of action as an antiviral is to prevent the uncoating of viral genome which inhibits ... This results in a longer period required until maximum shedding of the virus is reached. This also results in cell death only ...
The principal diseases studied are foot-and-mouth disease, classical swine fever, and vesicular stomatitis virus.[citation ... including classical swine fever and African swine fever. PIADC runs about 30,000 diagnostic tests each year. PIADC operates ... 2008). Germs, viruses, and secrets: government plans to move exotic disease research to the mainland United States: hearing ... Because federal law stipulates that live foot-and-mouth disease virus cannot be studied on the mainland, PIADC is unique in ...
... interacting protein involved in classical swine fever virus growth". Journal of Virology. 87 (4): 2072-80. doi:10.1128/JVI. ... study found that a Sus scrofa PRR29-like protein interacts with the N-terminal protease of classical swine fever virus (CSFV). ...
... bovine viral diarrhea virus NS3 endopeptidase, BVDV NS3 endopeptidase, classical swine fever virus NS3 endopeptidase, CSFV NS3 ... Xu J, Mendez E, Caron PR, Lin C, Murcko MA, Collett MS, Rice CM (July 1997). "Bovine viral diarrhea virus NS3 serine proteinase ... Tautz N, Kaiser A, Thiel HJ (August 2000). "NS3 serine protease of bovine viral diarrhea virus: characterization of active site ... Pestivirus NS3 polyprotein peptidase (EC 3.4.21.113, border disease virus NS3 endopeptidase, BDV NS3 endopeptidase, ...
Nipah virus infection, Rift Valley fever, capripox, lumpy skin disease, glanders, and classical swine fever. Animal Care - The ... Diseases of primary concern are: classical swine fever, African swine fever, Newcastle disease, and notifiable avian influenza ... classical swine fever, and Nipah and Hendra virus infections. The NCFAD has received designations by the World Organization for ... Hendra virus, Ebola virus and Rift Valley fever virus. The Section maintains a state of readiness for emergencies or outbreak ...
... including classical swine fever virus, and Hepacivirus genus, including Hepatitis C virus. The SVV IRES RNA shares similarities ... Positive stranded RNA virus transcription is the method of transcription. The virus exits the host cell by lysis, and ... "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 20 May 2021. Reddy ... Structure of Seneca Valley Virus-001 - on Virus Particle ExploreR (VIPERdb) Viralzone: Senecavirus ICTV (CS1 errors: missing ...
Bovine viral diarrhea virus type 2 (BVDV-2), Border disease virus (BDV), and Classical swine fever (CSF) virus are the four ... causes Bovine viral diarrhea and Mucosal disease Pestivirus C or Classical swine fever virus (CSFV), causes Classical swine ... "Identification of an NTPase motif in classical swine fever virus NS4B protein". Virology. 411 (1): 41-49. doi:10.1016/j.virol. ... "Establishment of a Dual SYBR Green I Fluorescence PCR Assay for African Swine Fever Virus and Porcine Epidemic Diarrhea Virus ...
... feline immunodeficiency virus (FIV), tuberculosis, Texas cattle fever, classical swine fever (hog cholera), heartworm, and ... Virus-typing of polio by Salk "Tireless polio research effort bears fruit and indignation". Archived from the original on 2008- ... Salk polio virus [2] History of polio vaccine "the work on [polio] prevention was long delayed by... misleading experimental ... In the 1940s, Jonas Salk used rhesus monkey studies to isolate the most virulent forms of the polio virus, which led to his ...
Feline immunodeficiency virus (FIV), tuberculosis, Texas cattle fever, Classical swine fever (hog cholera), Heartworm and other ... Virus-typing of polio by Salk [6] Salk polio virus [7] History of polio vaccine ""the work on [polio] prevention was long ... In the 1940s, Jonas Salk used rhesus monkey cross-contamination studies to isolate the three forms of the polio virus that ... Albert Sabin made a superior "live" vaccine by passing the polio virus through animal hosts, including monkeys. The vaccine was ...
... virus QI09AD03 Porcine reproductive and respiratory syndrome (PRRS) virus QI09AD04 Classical swine fever virus QI09AE01 ... porcine influenza virus QI09AA05 Porcine reproductive and respiratory syndrome (PRRS) virus QI09AA06 Classical swine fever ... QI09AA01 Aujeszky's disease virus QI09AA02 Porcine parvovirus QI09AA03 Porcine influenza virus QI09AA04 Aujeszky's disease ... erysipelothrix QI09AL04 Porcine influenza virus + erysipelothrix QI09AL05 Porcine transmissible gastro-enteritis virus + ...
Other members of this genus cause Border disease (sheep) and classical swine fever (pigs) which cause significant financial ... Ncp viruses can induce persistent infection in cells and have an intact NS2/3 protein. In cp viruses the NS2/3 protein is ... Animal viruses Fray, M.D; Paton, D.J; Alenius, S.; et al. (2000). "The effects of bovine viral diarrhoea virus on cattle ... The virus, therefore, entered the fetal cells and, during immune system development, was accepted as self. In PIs the virus ...
African swine fever virus (ASFV) is a large double-stranded DNA virus which replicates in the cytoplasm of infected cells and ... They cause Classical swine fever (CSF) and Bovine viral diarrhea(BVD). Mucosal disease is a distinct, chronic persistent ... West Nile virus, Israel turkey meningoencephalomyelitis virus, Sitiawan virus, Wesselsbron virus, yellow fever virus and the ... Flaviviruses include the West Nile virus, dengue virus, Tick-borne Encephalitis Virus, Yellow Fever Virus, and several other ...
... then returned to Minnesota and studied classical swine fever (also known as hog cholera). Bachrach found that the disease could ... Bachrach was able to purify the virus responsible for foot-and-mouth disease. In 1950, having spent a year in Europe, Bachrach ... The other 90% of the specimen was "gunk" from the cells involved in the process of growing the virus, but no previous ... "Howard Bachrach, pioneer in fight against polio and other viruses". Star Tribune. July 25, 2008. Retrieved June 2, 2016. George ...
International Committee on Taxonomy of Viruses. Retrieved 21 August 2019. ...Classical swine fever virus becomes Pestivirus C ... Classical Swine Fever, Iowa State University Species Profile - Classical Swine Fever, National Invasive Species Information ... "Classical Swine Fever-An Updated Review". Viruses. MDPI. 9 (4): 86. doi:10.3390/v9040086. PMC 5408692. PMID 28430168. Paton, D. ... Classical swine fever (CSF) or hog cholera (also sometimes called pig plague based on the German word Schweinepest) is a highly ...
... classical swine fever virus MeSH B04.909.777.411 - hepatitis delta virus MeSH B04.909.777.415 - hepatitis e virus MeSH B04.909. ... diarrhea virus 2, bovine viral MeSH B04.820.250.700.400 - classical swine fever virus MeSH B04.820.410.050 - allolevivirus MeSH ... yellow fever virus MeSH B04.820.250.400 - gb virus a MeSH B04.820.250.405 - gb virus b MeSH B04.820.250.410 - GB virus C MeSH ... rift valley fever virus MeSH B04.820.087.710.750 - sandfly fever naples virus MeSH B04.820.087.710.900 - uukuniemi virus MeSH ...
"African Swine Fever Summary sheets" (PDF). "Classical Swine Fever" (PDF). August 2008. "Classical Swine Fever (hog cholera) ... "With high virulent forms of the virus, ASF is characterized by high fever, loss of appetite, hemorrhages in the skin and ... Lesions of classical swine fever are clinico-pathologically indistinguishable from African swine fever; it is essential to send ... Classical swine fever was once widespread, but has been eradicated from many countries from domestic swine, including the US. A ...
... such as classical swine fever, avian influenza, Actinobacillus pleuropneumonia and Salmonella infections in pigs. Prior to the ... Eggs were used for virus propagation in the development of a yellow fever vaccine in 1935 and an influenza vaccine in 1945. In ... "Glycoprotein E1 of hog cholera virus expressed in insect cells protects swine from hog cholera". Journal of Virology. 67 (9): ... Viruses are grown either on primary cells such as chicken eggs (e.g., for influenza) or on continuous cell lines such as ...
The clinical symptoms of ASFV infection are very similar to classical swine fever, and the two diseases normally have to be ... Wikispecies has information related to African swine fever virus. Canadian Food Inspection Agency African swine fever ... Viruses portal Veterinary virology Dixon; et al. (2008). "African Swine Fever Virus". Animal Viruses: Molecular Biology. ... African swine fever virus (ASFV) is a large, double-stranded DNA virus in the Asfarviridae family. It is the causative agent of ...
"Negative impact of porcine reproductive and respiratory syndrome virus infection on the efficacy of classical swine fever ... simian hemorrhagic fever virus (SHFV), wobbly possum disease virus, and lactate dehydrogenase elevating virus (LDV). PRRSV is a ... virus isolate and the virus dose. It was shown that pigs could be infected with PRRS virus by several routes of exposure: ... immune response to swine influenza virus challenge in pigs infected with porcine reproductive and respiratory syndrome virus at ...
... formerly Classical swine fever virus) Foot-and-mouth disease virus Goatpox virus Lumpy skin disease virus Avian avulavirus 1 ( ... Rift Valley fever phlebovirus Venezuelan equine encephalitis virus African horse sickness virus African swine fever virus Avian ... formerly peste des petits ruminants virus) Rinderpest morbillivirus Sheeppox virus Swine vesicular disease virus Andes ... Far Eastern subtype Flavivirus Siberian subtype Flavivirus Kyasanur Forest disease virus Omsk hemorrhagic fever virus Variola ...
... modelling classical swine fever incursions in wild pigs in Australia". Veterinary Research. 43 (1): 3. doi:10.1186/1297-9716-43 ... Contemporary diseases of zoonotic origin include SARS, Lyme disease and West Nile virus. Disease emergence and resurgence in ... red grouse and louping ill virus". Journal of Applied Ecology. 47 (4): 926-930. doi:10.1111/j.1365-2664.2010.01834.x. ISSN 1365 ...
... bovine viral diarrhea virus 1) and Pestivirus C (classical swine fever virus, previously hog cholera virus)). Viruses in this ... Yellow fever virus, and Zika virus) Genus Hepacivirus (includes Hepacivirus C (hepatitis C virus) and Hepacivirus B (GB virus B ... Guaico Culex virus, Jingmen tick virus and Mogiana tick virus. These viruses have a segmented genome of 4 or 5 pieces. Two of ... These include Wenling shark virus. Jingmenvirus is a group of unclassified viruses in the family which includes Alongshan virus ...
African horse sickness virus African swine fever virus Avian influenza virus (highly pathogenic) Classical swine fever virus ... viruses: African VHF viruses: Crimean-Congo hemorrhagic fever virus Ebola virus* Lassa fever virus Lujo virus Marburg virus* ... Asian VHF viruses: Kyasanur Forest disease virus Omsk hemorrhagic fever virus South American VHF viruses: Chapare virus ... Hendra virus Nipah virus Rift Valley fever virus Venezuelan equine encephalitis virus (excluding enzootic subtypes ID and IE) ...
... african swine fever MeSH C22.905.170 - classical swine fever MeSH C22.905.260 - edema disease of swine MeSH C22.905.323 - ... marburg virus disease MeSH C22.735.500.850 - simian acquired immunodeficiency syndrome MeSH C22.735.750 - monkeypox MeSH ... swine erysipelas MeSH C22.905.850 - swine vesicular disease MeSH C22.905.927 - vesicular exanthema of swine The list continues ... of swine MeSH C22.905.626 - pneumonia of swine, mycoplasmal MeSH C22.905.700 - porcine reproductive and respiratory syndrome ...
... disease is considered to be the most economically important viral disease of swine in areas where classical swine fever (hog ... The virus is shed in the saliva and nasal secretions of swine infected by the respiratory route. Aerosolization of the virus ... Swine (both domestic and feral) are usual reservoirs for this virus, though it does affect other species. Aujeszky's disease ... Diagnosis is made mainly by virus isolation in tissue cultures, or through ELISA or PCR tests. Vaccines are available for swine ...
Some, like classical swine fever and scrapie are specific to one type of stock, while others, like foot-and-mouth disease ... This virus is easily transmissible to domestic poultry, and to humans living in close proximity with them. Other infectious ... "Classical swine fever" (PDF). The Center for Food Security and Public Health. Retrieved 20 May 2017. "Scrapie Fact Sheet". ... An outbreak of Nipah virus in Malaysia in 1999 was traced back to pigs becoming ill after contact with fruit-eating flying ...
... the Influenza A virus subtype H5N1 from 2004, the Ebola virus epidemic in West Africa and onwards. Mary Putnam Jacobi (1842- ... Known as swine flu, due to its indirect source from pigs, it went on to infect over 700 million people. The continuing HIV ... Harvard: Loeb Classical Library. Vallance JT (April 1993). "Herophilus: The Art of Medicine in Early Alexandria". Ancient ... In 1847 in Vienna, Ignaz Semmelweis (1818-1865), dramatically reduced the death rate of new mothers (due to childbed fever) by ...
Marion Dorsett, discovered in 1903 that swine fever (hog cholera) was caused by a virus; in 1935 he helped develop the crystal ... Private schools include Agathos Classical School, Zion Christian Academy and Columbia Academy. The city is home to the main ... that hog cholera is caused by an ultramicroscopic virus, and hogs recovered from the disease are immune for life." Sterling, ...
Machupo virus, Coronaviruses (especially SARS-Cov-2 that causes COVID-19), Marburg virus, Variola virus, and yellow fever virus ... African swine fever for pigs, and psittacosis to kill the chicken. These agents were prepared to spray them down from tanks ... It is important to note that most classical and modern biological weapons' pathogens can be obtained from a plant or an animal ... especially Rift Valley fever virus), Ebolavirus, many of the Flaviviridae (especially Japanese encephalitis virus), ...
"Ian Lipkin The Virus Hunter" (PDF). Discover. April 2012. Zimmer, Carl (November 22, 2010). "A Man From Whom Viruses Can't Hide ... Within this consortium, his research focused on pathogen discovery, using unexplained hemorrhagic fever, febrile illness, ... such as swine. Lipkin addressed a health forum in Guangzhou in January 2004 where China Daily reported him as saying: "SARS ... "classical gumshoe epidemiology" of "contact tracing and isolation" that brought swift action against the epidemic. Lipkin was ...
... suspected of being infected or in contact with the H1N1 virus during the global outbreak of swine flu. A 25-year-old Mexican ... It taught classical Chinese writings and Confucian ethics. In 1936, the Chinese Methodist Church (香港基督教循道衛理教會) moved its ... Every year the academy produces a number of Broadway musicals, including Singin' in the Rain, Saturday Night Fever, and Annie. ... "Swine flu scare: China puts 460 in isolation", The Times of India, 3 May 2009. "A historical and architectural appraisal of ...
Jihad fever swept northern Nigeria, with strong support among both the Fulani and the Hausa. Usman created an empire that ... The outbreak is caused by the Zaire ebolavirus, known simply as the Ebola virus (EBOV). It is the most severe outbreak of Ebola ... This is a legal designation used only twice before (for the 2009 H1N1 (swine flu) pandemic and the 2014 resurgence of polio) ... As part of this simulated narrative, post-classical Egypt has also been characterized as having plantations. Another part of ...
BDV, border disease virus; CSFV, classical swine fever virus.. †CSFV strains: Alfort187 (genotype 1.1), Diepholz (genotype 2.3 ... Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus Alexander Postel, Stefanie Schmeiser, Tuba Cigdem ... Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus. ... Boxes indicate virus neutralization test titers for homologous serum; boldface indicates results for Aydin/04 and Burdur/05. ...
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... is caused by classical swine fever virus (CSFV) and has lead huge losses to the pig industry worldwide. Although vaccination ... Background: Classical swine fever (CSF) is caused by classical swine fever virus (CSFV) and has lead huge losses to the pig ... Development and Application of a High Sensitivity Immunochromatographic Test Strip for Detecting Classical Swine Fever Virus ... No cross reaction with other swine virus antibodies was observed. The detection of clinical swine serum samples (n=138) ...
Diagnosis of classical swine fever virus in a limited resource setting: The influence of pig breed on methodology and sample ... Diagnosis of classical swine fever virus in a limited resource setting: The influence of pig breed on methodology and sample ...
Humoral and cellular immune response in mice induced by the classical swine fever virus E2 protein fused to the porcine CD154 ... Humoral and cellular immune response in mice induced by the classical swine fever virus E2 protein fused to the porcine CD154 ... Humoral and cellular immune response in mice induced by the classical swine fever virus E2 protein fused to the porcine CD154 ... and cellular immune response elicited in inbred BALB/c mice by immunization with a recombinant classical swine fever virus ( ...
BDV, border disease virus; CSFV, classical swine fever virus; boxes indicate virus neutralization test titers for homologous ... Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus Alexander Postel, Stefanie Schmeiser, Tuba Cigdem ... Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus. ...
T1 - Classical swine fever virus vs. Classical swine fever virus. T2 - The superinfection exclusion phenomenon in ... Classical swine fever virus vs. Classical swine fever virus: The superinfection exclusion phenomenon in experimentally infected ... Classical swine fever virus vs. Classical swine fever virus: The superinfection exclusion phenomenon in experimentally infected ... title = "Classical swine fever virus vs. Classical swine fever virus: The superinfection exclusion phenomenon in experimentally ...
... Filing Date: 2011.01.29 ... Description: A method for detecting CSFV kit comprising RNA inhibitor, AMV (avian myeloblastosis leukemia virus) reverse ...
CAN SCREWWORM CARRY AND SPREAD FOOT-AND-MOUTH DISEASE VIRUS AND CLASSICAL SWINE FEVER VIRUS? (Other) (17-Dec-05) ... COMPARISON OF CARBON DIOXIDE- AND OCTENOL-BAITED ENCEPHALITIS VIRUS SURVEILLANCE MOSQUITO TRAPS AT THE SHOAL WATER BAY TRAINING ...
Passage of classical swine fever virus in cultured swine kidney cells selects virus variants that bind to heparan sulfate due ... Classical swine fever virus (CSFV) is an enveloped positive-stranded RNA virus (20) of the genusPestivirusof the Flavi-viridae ... Interaction of classical swine fever virus with mem-brane-associated heparan sulfate: role for virus replication in vivo and ... RNase of classical swine fever virus: biochemical characteriza-tion and inhibicharacteriza-tion by virus-neutralizing ...
... of the pestivirus classical swine fever virus lead to virus attenuation, J. Virol. 73 (1999) 10224-10235. [PubMed]. . ... Classical swine fever virus replicon particles lacking the E$^{\rm rns}$ gene: a potential marker vaccine for intradermal ... Dong X.N., Wie K., Liu Z.Q., Chen Y.H., Candidate peptide vaccine induced protection against classical swine fever virus, ... Humoral and cell-mediated immune responses of d/d histocompatible pigs against classical swine fever (CSF) virus Vet. Res. 34, ...
The Unique Glycosylation at Position 986 on the E2 Glycoprotein of Classical Swine Fever Virus Is Responsible for Viral ...
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Genetically modified pigs are protected from classical swine fever virus. PLoS Pathog. (2018) 14:e1007193. doi: 10.1371/journal ... CRISPR-Cas9 has been used to knock-in resistance to the classical swine fever virus (CSFV) at the Rosa26 gene. This locus is a ... Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus. Nat Biotechnol. (2016) 20-2. doi: ...
Categories: Classical swine fever virus Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
African Swine Fever, Vesicular Stomatitis Virus, Classical Swine Fever and Foot-and-Mouth Disease Virus. Both agencies intend ...
New targets to fight Classical Swine Fever Virus. The Classical Swine Fever virus (CSFV) is a major pathogen of livestock. ...
Currently, U.S. commercial swine are free of both classical swine fever virus and pseudorabies virus because of costly ... "The emerging threat of classical swine fever virus and pseudorabies virus being reintroduced into U.S. commercial swine is ... "Classical swine fever virus and pseudorabies virus cause two of the top four transboundary animal diseases of importance to ... When looking at classical swine fever virus, two of the 12 ingredients had infectious virus detected: conventional soybean meal ...
African swine fever virus and atypical porcine pestivirus Classical swine fever (CSF), African swine fever (ASF), and atypical ... Development of a quadruple PCR-based gene microarray for detection of vaccine and wild-type classical swine fever virus, ... Hepatitis delta virus (HDV), a satellite virus of hepatitis B virus (HBV), is a small, defective RNA virus strongly associated ... As the virus evolves, so too must we: a drug developers perspective The SARS-CoV-2 virus has been raging globally for over 2 ...
Research Topic: Epitope mapping of the Classical Swine Fever Virus glycoprotein E2. Supervisor: Prof. Dr. Volker Moennig, ... Research Topic: Interaction of hepatitis B virus - hepatitis Delta Virus co-infection in a humanized mouse model. Supervisor: ... Research Topic: Infection of the respiratory epithelium by Canine distemper virus: importance of lipid rafts for virus entry ... Research Topic: Hepatitis C Virus - Human Immunodeficiency Virus Coinfection: Immune Mechanisms, Viral Interactions and ...
Infection with peste des petits ruminants virus. - Infection with classical swine fever virus Adopted amendments Proposed ... Infection with peste des petits ruminants virus (Chapter 14.7.). - Infection with classical swine fever virus (Chapter 15.2.). ... African swine fever. - Classical swine fever (CSF). - Avian influenza (AI) - Newcastle disease (ND). - Prescribed and ... Rift Valley fever. - Bovine tuberculosis. - Bovine spongiform encephalopathy. - Classical swine fever. - Avian influenza - ...
Classical swine fever virus B4.909.777.310.700.400 Clerodendrum B1.650.940.800.575.100.960.155 B1.650.940.800.575.100.583.520. ... African horse sickness virus B4.909.777.714.550.50 (Replaced for 2015 by African Horse Sickness Virus) African Swine Fever ... Rift Valley fever virus B4.909.777.147.710.700 Rinderpest virus B4.909.777.455.600.650.500.675 RING Finger Domains G2.111. ... Hemorrhagic Disease Virus, Rabbit B4.909.777.162.500.380 Hemorrhagic Fever Virus, Crimean-Congo B4.909.777.147.565.400 Hendra ...
Analysis of classical swine fever virus RNA replication determinants using replicons Peter Christian Risager, Ulrik Fahnøe, ... derived from the genome of the Paderborn strain of classical swine fever virus (CSFV) have been produced. The full-length viral ... RNA viruses * RAGE inhibits human respiratory syncytial virus syncytium formation by interfering with F-protein function Jane ... The 2009 swine-origin pandemic H1N1 (pH1N1) influenza virus transmitted and caused disease in many individuals immune to pre- ...
Classical swine fever virus suppresses maturation and modulates functions of monocyte-derived dendritic cells without ... 3. Pauly T, König M, Thiel H, Saalmüller A. Infection with classical swine fever virus: effects on phenotype and immune ... Interferon-induced protection against foot-and-mouth disease virus infection correlates with enhanced tissue-specific innate ... Thymic transplantation in miniature swine. I. Development and function of the "thymokidney". Transplantation. 1999;68:1684-92 ...
... caused by the classical swine fever virus (CSFV). CSFV is an enveloped, single-stranded RNA virus that belongs to the ... Classical Swine Fever (CSF) is a contagious, hemorrhagic and often fatal disease of Suidae, such as pigs and wild boar, ... Systems immunology approach for resolving the mechanisms of vaccine-induced classical swine fever protection, AP.R SPRINT ... distantly related for example to Zika and Yellow Fever virus. CSFV can be controlled by vaccination particularly usi… ...
Published data on wild pig ecology from Australia, and international Classical Swine Fever data was used to parameterise the ... exposed-infected-recovered process model that simulates the potential spread of classical swine fever through a documented, ... Classical swine fever transmission. The models treatment of virus transmission can be considered in two ways, transition of ... OIE: Classical Swine Fever: General Disease Information Sheets. Book Classical Swine Fever: General Disease Information Sheets ...
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Standardization and validation of qualitative realtime RT-PCR for detection of classical swine fever virus. Kim Lam Chiok, C., ... Standardization of real time RT-PCR technique for Infectious Pancreatic Necrosis virus (IPNV) detection in rainbow trout ( ...
Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this ... Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this ... Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this ... Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this ...
  • CSFV, classical swine fever virus. (cdc.gov)
  • Classical swine fever (CSF) is caused by classical swine fever virus (CSFV) and has lead huge losses to the pig industry worldwide. (researchsquare.com)
  • In this study, humoral and cellular immune response elicited in inbred BALB/c mice by immunization with a recombinant classical swine fever virus (CSFV) E2 protein fused to porcine CD154 antigen (E2CD154) was assessed. (edu.sa)
  • Therefore, this immunogen might be an appropriate candidate to elicit immune response in swine, control CSF disease and to eliminate CSFV in swine. (edu.sa)
  • Two groups with three wild boars each were used: Group A (animals 1 to 3) served as the control, and Group B (animals 4 to 6) was postnatally persistently infected with the Cat01 strain of CSFV (primary virus). (illinois.edu)
  • Additionally, in PBMCs, a well-known target for CSFV viral replication, only the primary infecting virus RNA (Cat01 strain) could be detected, even after the isolation in ST cells, demonstrating SIE at the tissue level in vivo. (illinois.edu)
  • Finally, a sequence analysis could not detect CSFV Margarita RNA in the samples tested from Group B. Our results suggested that the SIE phenomenon might be involved in the evolution and phylogeny of the virus, as well as in CSFV control by vaccination. (illinois.edu)
  • Classical swine fever virus (CSFV) is an enveloped positive-stranded RNA virus (20) of the genus Pestivirus of the Flavi-viridae family (34). (1library.net)
  • The Classical Swine Fever virus (CSFV) is a major pathogen of livestock. (peerj.com)
  • Classical Swine Fever (CSF) is a contagious, hemorrhagic and often fatal disease of Suidae, such as pigs and wild boar, caused by the classical swine fever virus (CSFV). (fapesp.br)
  • CSFV is an enveloped, single-stranded RNA virus that belongs to the Flaviviridae family (Moennig, 2000), distantly related for example to Zika and Yellow Fever virus. (fapesp.br)
  • It's laborious to diagnose the infections of classical swine fever virus (CSFV), porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus sort 2 (PCV2), and Suid herpesvirus 1 (SuHV-1) due to the same scientific signs in piglets. (computablegenomix.com)
  • It has been shown in clinical cases to be a commonly mixed infection with Pseudorabies virus (PRV), classical swine fever virus (CSFV), Porcine Reproductive and Respiratory Syndrome virus (PRRSV). (biomedcentral.com)
  • CSFV causes infected swine to develop a fever, excessive bleeding, lethargy, diarrhea that is yellow in color, retching, and purplish-colored skin discoloration of areas such as the ears, legs, and lower stomach. (iloveveterinary.com)
  • This is due to the clinical signs manifested by CSFV-infected pigs are also common with other diseases of swine. (iloveveterinary.com)
  • Classical swine fever virus (CSFV) is an enveloped positive-stranded. (city-made.com)
  • Control of classical swine fever virus (CSFV) in endemic countries relies on vaccination, mostly using vaccines that do not allow for differentiation of vaccinated from infected animals (DIVA). (bvsalud.org)
  • Megan Niederwerder , lead researcher and Kansas State assistant professor of diagnostic medicine and pathobiology, and her colleagues have published the first report of classical swine fever virus and pseudorabies virus stability in feed ingredients subjected to different environmental conditions mimicking transpacific shipment. (thepigsite.com)
  • "Stability of classical swine fever virus and pseudorabies virus in animal feed ingredients exposed to transpacific shipping conditions " is available online in the journal Transboundary and Emerging Diseases . (thepigsite.com)
  • Classical swine fever virus and pseudorabies virus cause two of the top four transboundary animal diseases of importance to swine," Niederwerder said. (thepigsite.com)
  • Currently, U.S. commercial swine are free of both classical swine fever virus and pseudorabies virus because of costly eradication programs completed in 1978 and 2004, respectively. (thepigsite.com)
  • Recent changes in pseudorabies virus strain virulence and classical swine fever virus geographic distribution are of great concern for these trade-limiting diseases. (thepigsite.com)
  • The emerging threat of classical swine fever virus and pseudorabies virus being reintroduced into U.S. commercial swine is significant and preventing entry is critical for the U.S. pork industry," Niederwerder said. (thepigsite.com)
  • However, the stability of classical swine fever virus and pseudorabies virus in imported feed ingredients had yet to be investigated. (thepigsite.com)
  • In the researchers' study, they found both viruses survived for the length of the 37-day model in feed, with pseudorabies virus having increased stability across a broader range of feed ingredients when compared to classical swine fever virus. (thepigsite.com)
  • Niederwerder said pseudorabies virus was detected in nine of the 12 tested ingredients: conventional and organic soybean meal, lysine, choline, vitamin D, moist cat and dog food, dry dog food, and pork sausage casings at the conclusion of the simulated voyage. (thepigsite.com)
  • This study reports novel data about environmental stability of classical swine fever virus and pseudorabies virus in feed and includes important quantitative information that can be incorporated into risk models for preventing the potential spread of classical swine fever virus and pseudorabies virus through imported feed ingredients," Niederwerder said. (thepigsite.com)
  • Samples are also tested for pseudorabies virus and swine brucellosis. (usda.gov)
  • He said in the year 2000, Uruguay's Ministry of Agriculture and the swine industry completed a serological study of pigs there, looking for antibodies of PRRS, pseudorabies virus (PRV), classical swine fever (CSF), and other diseases. (swinehealth.org)
  • The classical swine fever outbreak in The Netherlands during 1997 and 1998 resulted in destruction of more than 10 million pigs at a cost of more than 2 billion U.S. dollars (25). (1library.net)
  • Mintiens K., Deluyker H., Laevens H., Koenen F., Dewulf J., De Kruif A., Descriptive epidemiology of a classical swine fever outbreak in the Limburg Province of Belgium in 1997, J. Vet. (vetres.org)
  • The route of introducing and transmitting swine viruses through feed has been recognized since the 2013-2014 outbreak of porcine epidemic diarrhea virus. (thepigsite.com)
  • Stanojevic S., Valcic M., Stanojevic S., Radojicic S., Avramov S., Tambur Z. (2015): Simulation of a classical swine fever outbreak in rural areas of the Republic of Serbia. (agriculturejournals.cz)
  • Engel B, Bouma A, Stegeman A, Buist W, Elbers A, Kogut J, Dopfer D, Mart de Jong CM (2005): When can a veterinarian be expected to detect classical swine fever virus among breeding sows in a herd during an outbreak? (agriculturejournals.cz)
  • Today Fort Baker is a part of the Golden Gate National Park where they have a children's museum and activities on the location of the US Army's Biological Research Field Laboratory that was closed down when an outbreak of Q Fever swept the base in 1979. (home.blog)
  • More than 6,000 feral swine samples per year are collected and screened for these pathogens through this surveillance program, providing important information that helps protect domestic animals, wildlife and humans from a major zoonotic disease outbreak. (usda.gov)
  • The swine industry in Colombia is just as concerned about disease outbreak and spread as the US industry," he stated. (swinehealth.org)
  • Analysis and evaluation of mortality losses of the 2001 African swine fever outbreak, Ibadan, Nigeria. (waset.org)
  • Emergency assistance on control and eradication of an outbreak of African swine fever in Western Nigeria. (waset.org)
  • His primary scientific interests are in Outbreak, Veterinary medicine, Virology, Virus and Classical swine fever. (research.com)
  • His primary areas of investigation include Veterinary medicine, Outbreak, Virology, Wild boar and Influenza A virus subtype H5N1. (research.com)
  • The scientist's investigation covers issues in Wild boar, Veterinary medicine, African swine fever, Outbreak and Influenza A virus subtype H5N1. (research.com)
  • Niederwerder said reintroduction of these viruses into U.S. swine herds would be devastating and that there are concerns that feed ingredients incorporated into swine diets may serve as new sources for the spread of animal diseases with economic and welfare significance. (thepigsite.com)
  • SWINOSTICS' mobile diagnostic system is based on biosensing and photonics technologies that reliably and quickly detect swine viral diseases in minutes. (nationalhogfarmer.com)
  • The swine diseases field diagnostic toolbox is crucial not only for animal and food safety but also for human health in general," says Giusti. (nationalhogfarmer.com)
  • The NWDP collaborates with the National Feral Swine Damage Management Program on disease management, research, pathogen surveillance, emergency response, education and outreach regarding diseases of feral swine. (usda.gov)
  • Surveillance for feral swine diseases is conducted by the National Feral Swine Damage Management Program. (usda.gov)
  • Efforts primarily focus on early detection of diseases that are not currently in the US, including classical swine fever, African swine fever, and foot-and-mouth disease. (usda.gov)
  • It has been shown in clinical cases to be a commonly mixed infection with other important swine diseases which can aggravate the severity of the disease and bring serious economic losses to the pig industry. (biomedcentral.com)
  • The Swine Health Information Center (SHIC) has funded a near real-time global surveillance system for swine diseases. (swinehealth.org)
  • The US swine industry is free of several swine diseases now being identified in different countries throughout the world. (swinehealth.org)
  • Using an international network of veterinarians, academics and allied industry, SHIC has surveyed for swine diseases circulating in other countries for the last two years. (swinehealth.org)
  • SHIC has also funded researchers at the University of Minnesota to develop a more formal and regular way to monitor for emerging and circulating swine diseases around the world. (swinehealth.org)
  • Some new capabilities include a state-of-the-art necropsy laboratory, modern testing instruments, and specialized laboratory space to handle select agents, dangerous pathogens and highly toxic chemicals, increasing the laboratory's capacity to respond to high consequential and emerging animal diseases such as influenza viruses in birds and dogs,, foot-and-mouth-disease and classical swine fever, among others. (nj.gov)
  • A species of the PESTIVIRUS genus causing exceedingly contagious and fatal hemorrhagic disease of swine. (bvsalud.org)
  • African swine fever (ASF) is a highly contagious hemorrhagic viral disease of wild and domestic pigs, capable of killing entire herds and resulting in substantial economic and production losses globally. (usda.gov)
  • Swine influenza viruses (SIV) produce a highly contagious and worldwide distributed disease that can cause important economic losses to the pig industry. (bvsalud.org)
  • An acute, highly contagious disease affecting swine of all ages and caused by the CLASSICAL SWINE FEVER VIRUS . (bvsalud.org)
  • No cross reaction with other swine virus antibodies was observed. (researchsquare.com)
  • Furthermore, these animals were unable to elicit adaptive humoral (no E2-specific or neutralising antibodies) or cellular immune responses (in terms of IFN-γ-producing cells) after inoculation with the second virus. (illinois.edu)
  • The PIC's surface contains antibodies against the targeted swine viruses. (nationalhogfarmer.com)
  • When a sample containing a virus is passed over the sensors, this virus binds to the antibodies. (nationalhogfarmer.com)
  • A serosurveillance study was conducted to detect the presence of antibodies to African swine fever virus (ASFV) and Classical swine fever virus in pigs sampled from piggeries and Makurdi central slaughter slab in Benue State, Nigeria. (waset.org)
  • Detection of African swine fever virus (ASFV) antibodies in pigs in Taraba state north east Nigeria. (waset.org)
  • Seroprevalence of Classical Swine Fever Antibodies in Slaughtered Pigs at Bodija Municipal Abattoir, Ibadan, South West Nigeria. (waset.org)
  • The detection of clinical swine serum samples (n=138) demonstrated that the agreement of the new E2 test strip with three commercial ELISA kits was 88.40% (122/138), 86.23% (119/138), and 96.38% (133/138), respectively. (researchsquare.com)
  • Backer J.A., Brouwer H., van Schaik G., van Roermund H.J.W. (2011): Using mortality data for early detection of Classical Swine Fever in The Netherlands. (agriculturejournals.cz)
  • Taking into consideration the differences in the development of the pig industry in the two countries, in particular the difference in the rate of vaccination against PRRS, which is much higher in Germany, it seems plausible that the characteristics of the farm and overall health management greatly influence the success of PRRS virus detection in this kind of sample. (hipra.com)
  • A recent study 1 suggests that meconium-stained fetuses, along with those decomposed but not autolytic, are the best samples for detection of the PRRS virus in the thymus, lungs and serum of fetuses using PCR. (hipra.com)
  • Classical Swine Fever Virus Antibody (IgG) ELISA Kit is Available at Gentaur Genprice with the fastest delivery. (joplink.net)
  • CusabioHuman anti-epidemic hemorrhagic fever virus antibody (IgG) ELISA Kit is Available at Gentaur Genprice with. (joplink.net)
  • CusabioHuman Rabies Virus (RV) Antibody (IgG) ELISA Kit is Available at Gentaur Genprice with the fastest delivery.Online Order. (joplink.net)
  • CusabioDog rabies virus (RV) antibody (IgG) ELISA Kit is Available at Gentaur Genprice with the fastest delivery.Online Order Payment. (joplink.net)
  • Muasya D, Vanleeuwen J, Gitau G, McKenna S, Heider L, Muraya J. "Evaluation of antibody and antigen cross-reaction in Kenyan dairy cattle naturally infected with two pestiviruses: Bovine viral diarrhea virus and classical swine fever virus. (ac.ke)
  • The selected primers did not yield false positive or cross reactive results with other common swine pathogens, showing high specificity. (bvsalud.org)
  • Several different strategies for control and eradication of classical swine fever (CSF) were compared using a Monte Carlo method-based simulation model. (agriculturejournals.cz)
  • Meyers G., Saalmüller A., Büttner M., Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation, J. Virol. (vetres.org)
  • Especie del género PESTIVIRUS que causa una enfermedad hemorrágica muy contagiosa y fatal en los cerdos. (bvsalud.org)
  • His Classical swine fever study incorporates themes from Wild boar, Pestivirus and Vaccination. (research.com)
  • Here we use the epidemic data of the 1997-1998 epidemic of Classical Swine Fever (CSF) Virus in The Netherlands to address this question for CSF risks. (wur.nl)
  • Jalvingh Alien W, Nielen Mirjam, Maurice Huibert, Stegeman Arjan J, Elbers Armin R.W, Dijkhuizen Aalt A (1999): Spatial and stochastic simulation to evaluate the impact of events and control measures on the 1997-1998 classical swine fever epidemic in The Netherlands. (agriculturejournals.cz)
  • Both viruses are endemic to areas of the world where feed ingredients are manufactured and imported into the United States each year. (thepigsite.com)
  • Currently, this virus is endemic in farms and, although used limitedly, trivalent vaccine application is the most extended strategy to control SIV. (bvsalud.org)
  • Resveratrol also significantly reduced the replication of monkeypox virus, a zoonotic virus that is endemic in Western and Central Africa and causes human mortality. (researchgate.net)
  • African swine fever virus (ASFV) currently represents the biggest threat to the porcine industry worldwide, with high economic impact and severe animal health and welfare concerns. (bvsalud.org)
  • Outbreaks have occurred in Europe and Asia since ASFV was reintroduced into the continent in 2007 and, in 2021, ASFV was detected in the Caribbean, raising alarm about the reemergence of the virus in the Americas. (bvsalud.org)
  • Given the lack of vaccines against ASFV, control of the virus relies on molecular surveillance, which can be delayed due to the need for sample shipment to specialized laboratories. (bvsalud.org)
  • Kaden Volker, Lange Bodo (2001): Oral immunisation against classical swine fever (CSF): onset and duration of immunity. (agriculturejournals.cz)
  • Bouma A., De Smit A.J., De Kluijver E.P., Terpstra C., Moormann R.J., Efficacy and stability of a subunit vaccine based on glycoprotein E2 of classical swine fever virus, Vet. (vetres.org)
  • The Unique Glycosylation at Position 986 on the E2 Glycoprotein of Classical Swine Fever Virus Is Responsible for Viral Attenuation and Protection against Lethal Challenge. (amedeo.com)
  • Influenza virus infects host cells through membrane fusion, a process mediated by the low pH-induced conformational change of the viral surface glycoprotein haemagglutinin (HA). (microbiologyresearch.org)
  • Human respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infection. (microbiologyresearch.org)
  • 3. Pauly T, König M, Thiel H, Saalmüller A. Infection with classical swine fever virus: effects on phenotype and immune responsiveness of porcine T lymphocytes. (southernbiotech.com)
  • Interferon-induced protection against foot-and-mouth disease virus infection correlates with enhanced tissue-specific innate immune cell infiltration and interferon-stimulated gene expression. (southernbiotech.com)
  • Long-term persistent infection of swine monocytes/macrophages with African swine fever virus. (waset.org)
  • Risk factors for farm-level African swine fever infection in major pig-producing areas in Nigeria, 1997-2011. (waset.org)
  • Abortion in the later stages of pregnancy is the clinical manifestation of PRRS virus infection that causes most concern to farmers. (hipra.com)
  • Even though much research has been done, the pathogenesis of intrauterine PRRS virus infection remains largely unknown. (hipra.com)
  • If the herd management and housing conditions are adequate, outbreaks of late abortions are usually attributed to an acute PRRS virus infection . (hipra.com)
  • However, infection with the PRRS virus was confirmed in only 8.6% of the samples. (hipra.com)
  • The selection of samples to confirm the presence of the PRRS virus in cases of abortion may also influence the outcome of the PCR , as can be deduced from the accumulated scientific evidence on the distribution of the PRRS virus in maternal and fetal tissues in cases of transplacental infection. (hipra.com)
  • Meconium staining was the most consistent gross abnormality observed in fetuses infected with the PRRS virus in another study 2 , suggesting that this is a reliable indicator of intrauterine infection. (hipra.com)
  • All in all, demonstration of PRRS virus infection in late-term aborted fetuses can be improved by sampling both meconium-stained and decomposed (non-autolytic) fetuses, umbilical cord and placenta on the farm. (hipra.com)
  • Dahle J., Liess B., A review on classical swine fever infections in pigs: epizootiology, clinical disease and pathology, Comp. (vetres.org)
  • Pigs or hogs are then infected with a highly virulent of one or more strains of the virus. (iloveveterinary.com)
  • In subacute and chronic cases, the pigs are infected by mildly virulent strains of the virus. (iloveveterinary.com)
  • Minimize visitors on your farm and do not allow persons who have had contact with animals in the last five days, especially swine in other countries to have contact with your pigs. (iloveveterinary.com)
  • Good communication between veterinary authorities, veterinary practitioners, and pig farmers, together with a reliable disease reporting system, and hygiene measures protecting domestic pigs from contact with wild boar are the most effective measures to prevent the disease from spreading and causing havoc amongst herds of swine in the area. (iloveveterinary.com)
  • Clinically severe acute disease of cattle caused by noncytopathic forms of Bovine viral diarrhea virus 2 (DIARRHEA VIRUS 2, BOVINE VIRAL). (bvsalud.org)
  • SWINOSTICS tool detects six viruses: African swine fever, PRRS, porcine parvovirus, porcine circovirus type 2, classical swine fever and swine influenza. (nationalhogfarmer.com)
  • Porcine Circovirus type 2 (PCV2), and Japanese Encephalitis virus (JEV), which can aggravate the severity of the disease and bring serious economic losses to the pig industry [ 3 ]. (biomedcentral.com)
  • Bovine viral diarrhea virus and Border disease virus of sheep. (1library.net)
  • Putative T7 promoter-derived transcript transcribed either in vitro or in vivo in BHK-21 cells infected by recombinant vaccinia virus vTF7-3 containing pXLCSFV130-423. (iresite.org)
  • Now in Uruguay they are investigating where the PRRS virus came from using sequencing to characterize the genome. (swinehealth.org)
  • Although this is the standard procedure for PRRS virus identification in clinical material coming from abortion, a high proportion of PCR-negative results are the most common outcome from the diagnostic laboratory, as was reported in a large-scale study in Germany. (hipra.com)
  • ABSTRACT Understanding the genetic evolution of A(H1N1)pdm09 and H3N2 viruses can help better select strains to be included in the annual influenza vaccine. (who.int)
  • His Epidemiology research is multidisciplinary, incorporating elements of Zoology and Highly Pathogenic Avian Influenza Virus. (research.com)
  • Epidemiology of classical swine fever in Germany in the 1990s. (research.com)
  • His study in the field of Virus and Vaccination also crosses realms of Molecular epidemiology and Western europe. (research.com)
  • His studies in African swine fever integrate themes in fields like Surveillance data, Epidemiological surveillance, Epidemiology and Seroprevalence. (research.com)
  • His work on Highly Pathogenic Avian Influenza Virus as part of general Virus research is frequently linked to Reassortment, bridging the gap between disciplines. (research.com)
  • African Swine Fever, Vesicular Stomatitis Virus, Classical Swine Fever and Foot-and-Mouth Disease Virus. (usda.gov)
  • This information adds to our work on African swine fever and reinforces the concept of feed biosecurity for disease prevention. (thepigsite.com)
  • African swine fever was eradicated in Malta by killing every pig in the country. (uia.org)
  • ASF or African Swine Fever is the headlining differential because it has a similar clinical manifestation. (iloveveterinary.com)
  • 4] Awosanya E. J., Olugasa B., Ogundipe G and Grohn Y. P. (2015): Seroprevalence and risk factors associated with African swine fever on pig farms in southwest Nigeria. (waset.org)
  • African swine fever: how can global spread be prevented? (waset.org)
  • Surveillance of African swine fever in Nigeria, 2006-2009. (waset.org)
  • Field surveillance and laboratory diagnoses of African swine fever in Nigeria (IAEA-CN-174-151). (waset.org)
  • He interconnects Classical swine fever, African swine fever, Epidemiological surveillance and Pseudorabies in the investigation of issues within Wild boar. (research.com)
  • African Swine Fever: Fast and Furious or Slow and Steady? (research.com)
  • Analysis of Estonian surveillance in wild boar suggests a decline in the incidence of African swine fever. (research.com)
  • Christoph Staubach mostly deals with Wild boar, African swine fever, Disease, Serology and Goose. (research.com)
  • The 2009 swine-origin pandemic H1N1 (pH1N1) influenza virus transmitted and caused disease in many individuals immune to pre-2009 H1N1 influenza virus. (microbiologyresearch.org)
  • Classical swine fever has occurred in Australia, where it is considered an exotic disease, four times, the last in 1961. (uia.org)
  • The Army called it an accident as they were experimenting on Sheep and goats that just so happen to have Q Fever, and the disease infected the base. (home.blog)
  • During Desert Storm the Army claimed that the disease Q Fever had infected its soldiers in the field and that this was the first time it was seen by the military. (home.blog)
  • They can be reservoirs of disease and may act as a host to a number of parasites, leaving the United States domestic swine industry vulnerable to disease. (usda.gov)
  • The Swine Health Information Center (SHIC) mission includes global disease monitoring. (swinehealth.org)
  • His Goose research includes elements of Severe disease, Influenza A virus subtype H5N1 and Virology. (research.com)
  • Caprine Arthritis-Encephalitis Virus (CAEV) is an incurable disease of goats that has both social and economic impacts. (bepress.com)
  • The development of subunit vaccines against classical swine fever is a desirable goal, because it allows discrimination between vaccinated and infected animals. (edu.sa)
  • There are variants of those viruses that might cause infections that aren't obvious but still there. (swinehealth.org)
  • The diagnosis of the classical swine fever virus is based on factors such as clinical signs, serology, virus isolation, and PCR. (iloveveterinary.com)
  • Anonymous (2002): Commission Decision of 1 February 2002 approving a Diagnostic Manual establishing diagnostic procedure, sampling methods and criteria for evaluation of the laboratory tests for the confirmation of classical swine fever. (agriculturejournals.cz)
  • In these cases the sample used to confirm the presence of the virus in the laboratory is the aborted material, usually accomplished by the polymerase chain reaction assay (PCR). (hipra.com)
  • Moreover, it is compatible with sensors designed to detect any type of virus. (nationalhogfarmer.com)
  • Although aborted material is sent to the lab in an attempt to detect the virus, the result is often frustrating. (hipra.com)
  • RAGE appeared to interact directly with the F protein, but, rather than inhibiting RSV entry into host cells, virus replication and budding, membrane-expressed RAGE or soluble RAGE blocked F-protein-mediated syncytium formation and sloughing. (microbiologyresearch.org)
  • The first section of this review describes types of viral fusion proteins and is followed by a comparison of the structural features of class I fusion proteins, namely influenza virus hemagglutinin and the S-protein of the human coronavirus. (bvsalud.org)
  • What's the risk for spread of classical swine fever and pseudorabies through feed? (thepigsite.com)
  • Epstein-Barr virus (EBV) is a wide-spread human herpesvirus that is highly associated with infectious mononucleosis and several malignancies. (biomedcentral.com)
  • This paper describes a spatio-temporal, stochastic, susceptible- exposed-infected-recovered process model that simulates the potential spread of classical swine fever through a documented, large and free living wild pig population following a simulated incursion. (biomedcentral.com)
  • Because clinical symptoms are not severe, outbreaks caused by low virulent strains may pass unnoticed for weeks or months, thus giving rise to a considerable spread of the virus. (uia.org)
  • Swine fever is widely spread throughout the tropical countries of Latin America and Southeast Asia. (uia.org)
  • rarely, it happens that the virus is spread by aerosol in close confinement or by vectors. (iloveveterinary.com)
  • Swine fever, having a high mortality rate, can cause severe economic losses among livestock. (uia.org)
  • König M., Lengsfeld T., Pauly T., Stark R., Thiel H.J., Classical swine fever virus: independent induction of protective immunity by two structural glycoproteins, J. Virol. (vetres.org)
  • These studies highlight the importance of vaccinating against immunodominant T-cell epitopes to provide for a more effective strategy to control influenza virus through heterosubtypic immunity. (microbiologyresearch.org)
  • The presence of pre-existing immunity against SIV may modulate the evolutionary dynamic of this virus. (bvsalud.org)
  • When looking at classical swine fever virus, two of the 12 ingredients had infectious virus detected: conventional soybean meal and pork sausage casings. (thepigsite.com)
  • Bovine Rhinotracheitis Virus - The infectious bovine rhinotracheitis (IBR) virus belongs to the group of herpes viruses. (home.blog)
  • Differential diagnosis of a swine epizootic of unknown aetiology in Ibadan, Oyo State, Nigeria. (waset.org)
  • The results show that despite homology shared between pre-2009 H1N1 and pH1N1 strains, the effector memory T-cell response to pre-2009 H1N1 was generally ineffective, a finding that correlated with lung virus persistence. (microbiologyresearch.org)
  • Armengol E., Wiesmüller K.-H., Wienhold D., Büttner M., Pfaff E., Jung G., Saalmüller A., Identification of T-cell epitopes in the structural and non-structural proteins of classical swine fever virus, J. Gen. Virol. (vetres.org)
  • The underlying mechanisms allowing West Nile virus (WNV) to replicate in a large variety of different arthropod, bird and mammal species are largely unknown but are believed to rely on highly conserved proteins relevant for viral entry and replication. (microbiologyresearch.org)
  • A number of enveloped viruses confer fusion of the viral envelope and the cell membrane using surface viral fusion proteins. (bvsalud.org)