Isocoumarins found in ASPERGILLUS OCHRACEUS and other FUNGI. Ochratoxin contaminated FOOD has been responsible for cases of FOODBORNE DISEASES.
4-Hydroxy-4H-furo(3,2-c)pyran-2(6H)-one. A mycotoxin produced by several species of Aspergillus and Penicillium. It is found in unfermented apple and grape juice and field crops. It has antibiotic properties and has been shown to be carcinogenic and mutagenic and causes chromosome damage in biological systems.
A mitosporic Trichocomaceae fungal genus that develops fruiting organs resembling a broom. When identified, teleomorphs include EUPENICILLIUM and TALAROMYCES. Several species (but especially PENICILLIUM CHRYSOGENUM) are sources of the antibiotic penicillin.
Compounds with a core of fused benzo-pyran rings.
Antibiotic and mycotoxin from Aspergillus niveus and Penicillium citrinum.
Natural or synthetic dyes used as coloring agents in processed foods.
Toxic compounds produced by FUNGI.
Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.
Compounds that differ from COUMARINS in having the positions of the ring and ketone oxygens reversed so the keto oxygen is at the 1-position of the molecule.
Resorcinols are aromatic organic compounds containing two hydroxyl groups attached to a benzene ring, known for their antiseptic and antibacterial properties, used in various medical and cosmetic applications.
The industry concerned with processing, preparing, preserving, distributing, and serving of foods and beverages.
The application of heat to raise the temperature of the environment, ambient or local, or the systems for accomplishing this effect. It is distinguished from HEAT, the physical property and principle of physics.
Organisms that live in water.
Any normal or abnormal coloring matter in PLANTS; ANIMALS or micro-organisms.
The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.
"Esters are organic compounds that result from the reaction between an alcohol and a carboxylic acid, playing significant roles in various biological processes and often used in pharmaceutical synthesis."
Large enzyme complexes composed of a number of component enzymes that are found in STREPTOMYCES which biosynthesize MACROLIDES and other polyketides.
A genus of mitosporic fungi containing about 100 species and eleven different teleomorphs in the family Trichocomaceae.
The presence of bacteria, viruses, and fungi in food and food products. This term is not restricted to pathogenic organisms: the presence of various non-pathogenic bacteria and fungi in cheeses and wines, for example, is included in this concept.
Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.
A phylum of fungi which have cross-walls or septa in the mycelium. The perfect state is characterized by the formation of a saclike cell (ascus) containing ascospores. Most pathogenic fungi with a known perfect state belong to this phylum.
Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
The functional hereditary units of FUNGI.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.

Mycotoxin determinations on animal feedstuffs and tissues in Western Canada. (1/45)

Results of examination of specimens of plant or animal origin for various mycotoxins are presented. Analyses for aflatoxins and ochratoxins were most frequently requested, usually on the basis of visible mouldiness. Aflatoxin B1 was found in one of 100 specimens at a level of 50 ppb in a sample of alfalfa brome hay. Ochratoxin A was detected in seven of 95 specimens comprising six samples of wheat at levels between 30 and 6000 ppb and one sample of hay at a level of 30 ppb. An overall detection rate of 4.2% involving significant levels of potent mycotoxins suggests that acute or chronic mycotoxicoses may occur in farm livestock or poultry more frequently than presently diagnosied.  (+info)

Medium-chain fatty acids affect citrinin production in the filamentous fungus Monascus ruber. (2/45)

During submerged culture in the presence of glucose and glutamate, the filamentous fungus Monascus ruber produces water-soluble red pigments together with citrinin, a mycotoxin with nephrotoxic and hepatoxic effects on animals. Analysis of the (13)C-pigment molecules from mycelia cultivated with [1-(13)C]-, [2-(13)C]-, or [1, 2-(13)C]acetate by (13)C nuclear magnetic resonance indicated that the biosynthesis of the red pigments used both the polyketide pathway, to generate the chromophore structure, and the fatty acid synthesis pathway, to produce a medium-chain fatty acid (octanoic acid) which was then bound to the chromophore by a trans-esterification reaction. Hence, to enhance pigment production, we tried to short-circuit the de novo synthesis of medium-chain fatty acids by adding them to the culture broth. Of fatty acids with carbon chains ranging from 6 to 18 carbon atoms, only octanoic acid showed a 30 to 50% stimulation of red pigment production, by a mechanism which, in contrast to expectation, did not involve its direct trans-esterification on the chromophore backbone. However, the medium- and long-chain fatty acids tested were readily assimilated by the fungus, and in the case of fatty acids ranging from 8 to 12 carbon atoms, 30 to 40% of their initial amount transiently accumulated in the growth medium in the form of the corresponding methylketone 1 carbon unit shorter. Very interestingly, these fatty acids or their corresponding methylketones caused a strong reduction in, or even a complete inhibition of, citrinin production by M. ruber when they were added to the medium. Several data indicated that this effect could be due to the degradation of the newly synthesized citrinin (or an intermediate in the citrinin pathway) by hydrogen peroxide resulting from peroxisome proliferation induced by medium-chain fatty acids or methylketones.  (+info)

Mycotoxin-producing potential of mold flora of dried beans. (3/45)

To evaluate the potential for mycotoxin production by molds in dried beans, the mold flora of 114 samples was determined both before and after surface disinfection of the beans with 5% NaOCl. Surface disinfection substantially reduced mold incidence, indicating that contamination was mainly on the surface. The flora, both before and after disinfection, was dominated by species of the Aspergillus glaucus group, the toxicogenic species A ochracues, Penicillium cyclopium, and P. viridicatum, and species of Alternaria, Cladosporium, and Fusarium. The toxicogenic species Aspergillus flavis, A. versicolor, Penicillium Citrinum, P. expansum, P. islandicum, and P. urticae were encountered less frequently. Of 209 species of Aspergillus and Penicillium screened for mycotoxin production on sterile rice substrate, 114 produced one or more of the following mycotoxins: A. flavus, aflatoxins; A. ochraceus, ochratoxins; A. nidulans, A. unguis, and A. versicolor, sterigmatocystin; P. cyclopium, penicillic acid; P. citrinum and P. viridicatum, citrinin; P. urticae, patulin and griseofulvin. Sterigmatocystin production by A. unguis is reported for the first time.  (+info)

The effects of aeration on glucose catabolism in Penicillium expansum. (4/45)

Polyacrylamide-disc gel electrophoresis and quantitative enzyme assays showed that the pathways of glucose catabolism and secondary metabolism in Penicillium expansum were dependent on the degree of aeration of the cultures. The isoenzyme patterns and specific activities of aldolase and succinate dehydrogenase indicated that glycolysis and the tricarboxylic acid cycle operated under conditions of both limited and efficient aeration (i.e. in cultures grown statically or on an orbital shaker). At high levels of aeration the growth rate was faster and synthesis of extracellular pectolytic enzymes was enhanced, whilst the activities of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase showed that the pentose-phosphate shunt was important in glucose catabolism during the trophophase of growth. In contrast, under conditions of low aeration this latter pathway was virtually undetectable, growth was slower, pectolytic enzyme production low and large concentrations of secondary metabolites (6-methylsalicylic acid, patulin and citrinin) accumulated.  (+info)

A major decomposition product, citrinin H2, from citrinin on heating with moisture. (5/45)

Citrinin is one of the mycotoxins produced by Penicillium citrinum. We examined the decomposition products after heating citrinin in water at 140 degrees C and isolated a major product, citrinin H2 (3-(3,5-dihydroxy-2-methylphenyl)-2-formyloxy-butane). Citrinin H2 did not show significant cytotoxicity to HeLa cells up to a concentration of 200 microg/ml (% cytotoxicity: 39%) in 63 h of incubation, but citrinin showed severe toxicity at a concentration of 25 microg/ml (% cytotoxicity: 73%). HPLC analysis of citrinin after heating under various conditions indicates that citrinin H2 is mainly yielded from citrinin.  (+info)

Simple and sensitive determination of citrinin in Monascus by GC-selected ion monitoring mass spectrometry. (6/45)

A new method for the qualitative and quantitative analysis of citrinin in Monascus by gas-chromatography-selected ion monitoring (SIM) mass spectrometry has been developed. GC separation of citrinin in Monascus extract was achieved without the need for chemical derivatization, and could be detected as a single peak when the SIM mode selected 5 prominent fragmentations (m/z of 220, 205, 177, 105 and 91). The quantitative detection limit for citrinin was approximately 1 ppb. Finally, the GC-separated analyte from Monascus extract, at a retention time of 10.89 min, was examined by the method of pattern recognition by comparison with a citrinin standard. The results show that the 2 compounds had a 94% similarity when the SIM mode was used.  (+info)

Mycotoxins. (7/45)

Mycotoxins are secondary metabolites produced by microfungi that are capable of causing disease and death in humans and other animals. Because of their pharmacological activity, some mycotoxins or mycotoxin derivatives have found use as antibiotics, growth promotants, and other kinds of drugs; still others have been implicated as chemical warfare agents. This review focuses on the most important ones associated with human and veterinary diseases, including aflatoxin, citrinin, ergot akaloids, fumonisins, ochratoxin A, patulin, trichothecenes, and zearalenone.  (+info)

Effect of citrinin and in association with aflatoxin B(1) on the infectivity and proliferation of Toxoplasma gondii in vitro. (8/45)

Macrophages exposed to 10 mug/mL citrinin (CTR) or 0.01 mug CTR mixed with 0.04 mug aflatoxin B1 (AFB1) for a period of 2 h at 37 masculine C, were infected with 10(6) Toxoplasma gondii tachyzoites/muL. The parasites were treated with mycotoxins (2 h at 37 masculine C) before being added to the macrophage culture. The number of tachyzoites was quantified 2, 24, 48, 72 and 96 h after infection. During the first 2 hours, 59% infectivity was observed in the control. After exposure to CTR or the mixture of toxins (CTR-AFB1), macrophages were infected with 77.5% and 75% of the inoculated tachyzoites, respectively. Similarly, 72.3% of the cells were infected when cultured together with previously treated parasites. The treatment with CTR-AFB1 gave rise to 2.9 times more tachyzoites than the control at 72 h. An increased number of parasites was recovered from macrophages exposed to CTR after 96 h, and to CTR-AFB1 after 72 h of culture; The number of tachyzoites recovered from the supernatant was 1.94 and 2.06 times higher, respectively, than in the control (5 x 10(5) +/- 0.054 /mL).  (+info)

Ochratoxins are a type of mycotoxin, which are toxic compounds produced by certain types of molds or fungi. Specifically, ochratoxins are produced by several species of Aspergillus and Penicillium molds that can contaminate a variety of agricultural crops, such as grains, nuts, coffee beans, dried fruits, and wine.

Ochratoxin A is the most prevalent and studied member of this family of mycotoxins. It is known to have nephrotoxic, immunotoxic, teratogenic, and carcinogenic effects in various animal species. In humans, exposure to ochratoxin A has been linked to kidney disease, developmental toxicity, and possibly cancer.

Ochratoxins can enter the human body through the consumption of contaminated food or drink. Once inside, they can accumulate in tissues, particularly in the kidneys, where they can cause damage over time. It is important to note that exposure to ochratoxins should be minimized to reduce the risk of health effects.

Patulin is a mycotoxin, a type of toxic chemical produced by certain molds (fungi). The mold that produces patulin grows on various fruits and vegetables, including apples, pears, and grapes. It can also be found in other foods such as grains, cheese, and processed apple products like apple juice and apple cider.

Patulin is a low molecular weight lactone and can be produced by several species of Penicillium, Aspergillus, and Byssochlamys. It is known to have antibiotic properties and has been studied for its potential use in medicine. However, at high concentrations, it can be toxic to humans and animals, causing damage to the nervous system, gastrointestinal tract, and immune system.

Exposure to patulin can occur through ingestion of contaminated food or drink. Regulatory bodies have set limits on the amount of patulin allowed in food and drinks to minimize the risk of human exposure.

"Penicillium" is not a medical term per se, but it is a genus of mold that is widely used in the field of medicine, specifically in the production of antibiotics. Here's a scientific definition:

Penicillium is a genus of ascomycete fungi that are commonly found in the environment, particularly in soil, decaying vegetation, and food. Many species of Penicillium produce penicillin, a group of antibiotics with activity against gram-positive bacteria. The discovery and isolation of penicillin from Penicillium notatum by Alexander Fleming in 1928 revolutionized the field of medicine and led to the development of modern antibiotic therapy. Since then, various species of Penicillium have been used in the industrial production of penicillin and other antibiotics, as well as in the production of enzymes, organic acids, and other industrial products.

Benzopyrans are a class of chemical compounds that contain a benzene ring fused to a pyran ring. They are also known as chromenes. Benzopyrans can be found in various natural sources, including plants and fungi, and have been studied for their potential biological activities. Some benzopyrans have been found to have anti-inflammatory, antioxidant, and anticancer properties. However, some benzopyrans can also be toxic or have other adverse health effects, so it is important to study their properties and potential uses carefully.

Citrinin is a mycotoxin, which is a toxic compound produced by certain types of fungi. It is commonly produced by Penicillium citrinum and Aspergillus terreus. Citrinin has been found to contaminate various food and feed commodities, including cereals, fruits, vegetables, and dairy products.

Clinically, citrinin exposure can cause a range of toxic effects in humans and animals, including nephrotoxicity (kidney damage), hepatotoxicity (liver damage), genotoxicity (damage to DNA), and immunotoxicity (suppression of the immune system). Symptoms of citrinin poisoning may include nausea, vomiting, diarrhea, abdominal pain, increased urination, and kidney failure.

It is important to note that citrinin contamination in food and feed can be minimized through proper storage, handling, and processing practices. Additionally, regulatory limits have been established in many countries to control the levels of citrinin in food and feed.

Food coloring agents, also known as food dyes, are substances that are added to foods and beverages to improve or modify their color. They are typically made from synthetic chemicals, although some are derived from natural sources. Food coloring agents are subject to regulation by the U.S. Food and Drug Administration (FDA) and other regulatory bodies to ensure their safety.

Food coloring agents are used for a variety of reasons, including:

* Making foods look more appealing or attractive
* Restoring the natural color of foods that has been lost during processing
* Helping consumers identify products, such as flavors or varieties of candy
* Ensuring consistency in the color of a product from batch to batch

Some common food coloring agents include:

* Blue 1 (Brilliant Blue)
* Blue 2 (Indigo Carmine)
* Green 3 (Fast Green FCF)
* Red 3 (Erythrosine)
* Red 40 (Allura Red)
* Yellow 5 (Tartrazine)
* Yellow 6 (Sunset Yellow)

It is important to note that some people may be sensitive or allergic to certain food coloring agents and may experience adverse reactions after consuming them. Additionally, there has been some concern about the potential health effects of artificial food dyes, although current research does not support a strong link between their consumption and negative health outcomes in the general population.

Mycotoxins are toxic secondary metabolites produced by certain types of fungi (molds) that can contaminate food and feed crops, both during growth and storage. These toxins can cause a variety of adverse health effects in humans and animals, ranging from acute poisoning to long-term chronic exposure, which may lead to immune suppression, cancer, and other diseases. Mycotoxin-producing fungi mainly belong to the genera Aspergillus, Penicillium, Fusarium, and Alternaria. Common mycotoxins include aflatoxins, ochratoxins, fumonisins, zearalenone, patulin, and citrinin. The presence of mycotoxins in food and feed is a significant public health concern and requires stringent monitoring and control measures to ensure safety.

Nephrosis is an older term that was used to describe a group of kidney diseases, primarily characterized by the damage and loss of function in the glomeruli - the tiny filtering units within the kidneys. This results in the leakage of large amounts of protein (primarily albumin) into the urine, a condition known as proteinuria.

The term "nephrosis" was often used interchangeably with "minimal change nephropathy," which is a specific type of kidney disorder that demonstrates little to no changes in the glomeruli under a microscope, despite significant protein leakage. However, current medical terminology and classifications prefer the use of more precise terms to describe various kidney diseases, such as minimal change disease, focal segmental glomerulosclerosis, or membranous nephropathy, among others.

It is important to consult with a healthcare professional or refer to updated medical resources for accurate and current information regarding kidney diseases and their specific diagnoses.

Isocoumarins are a type of chemical compound that contains a benzene ring fused to a five-membered lactone ring, which is made up of one oxygen atom and four carbon atoms. This particular structure gives isocoumarins their unique chemical and biological properties. They can be found naturally in various plants and microorganisms, and have been shown to exhibit a range of pharmacological activities, including anti-inflammatory, antimicrobial, and anticancer effects. Some isocoumarins are also used as starting materials for the synthesis of other chemical compounds.

Resorcinols are a type of chemical compound that contain a resorcinol moiety, which is made up of a benzene ring with two hydroxyl groups in the ortho position. In medicine, resorcinol and its derivatives have been used for various purposes, including as antiseptics, antibacterials, and intermediates in the synthesis of other pharmaceuticals.

Resorcinol itself has some medicinal properties, such as being able to reduce pain and inflammation, and it has been used topically to treat conditions like eczema, psoriasis, and acne. However, resorcinol can also be toxic in large amounts, so it must be used with caution.

It's important to note that while resorcinol is a chemical compound, the term "resorcinols" may also refer to a group of related compounds that contain the resorcinol moiety. These compounds can have different medicinal properties and uses depending on their specific structure and function.

I'm sorry for any confusion, but "Food Industry" is not a term that has a medical definition. The food industry is a broad category that includes businesses involved in the production, processing, packaging, distribution, and sale of food products. This can include farms, fisheries, manufacturers of food products, grocery stores, restaurants, and more.

If you have any questions related to nutrition or dietary habits and their impact on health, I would be happy to help provide information based on medical knowledge.

In the context of medical terminology, "heating" generally refers to the application of heat to an area of the body for therapeutic purposes. This can be done using various methods such as hot packs, heating pads, warm compresses, or even heated wax. The goal of applying heat is to increase blood flow, reduce pain and muscle spasms, and promote healing in the affected area. It's important to note that excessive heating or application of heat to sensitive areas should be avoided, as it can lead to burns or other injuries.

'Aquatic organisms' are living beings that inhabit bodies of water, such as oceans, seas, lakes, rivers, and ponds. This group includes a wide variety of species, ranging from tiny microorganisms like plankton to large marine mammals like whales. Aquatic organisms can be divided into several categories based on their specific adaptations to their environment, including:

1. Plankton: small organisms that drift with the water currents and include both plants (phytoplankton) and animals (zooplankton).
2. Nekton: actively swimming aquatic organisms, such as fish, squid, and marine mammals.
3. Benthos: organisms that live on or in the bottom of bodies of water, including crustaceans, mollusks, worms, and some types of algae.
4. Neuston: organisms that live at the air-water interface, such as certain species of insects and small fish.

Aquatic organisms play a critical role in maintaining the health and balance of aquatic ecosystems, providing food and habitat for other species, and contributing to global nutrient cycling and climate regulation.

Biological pigments are substances produced by living organisms that absorb certain wavelengths of light and reflect others, resulting in the perception of color. These pigments play crucial roles in various biological processes such as photosynthesis, vision, and protection against harmful radiation. Some examples of biological pigments include melanin, hemoglobin, chlorophyll, carotenoids, and flavonoids.

Melanin is a pigment responsible for the color of skin, hair, and eyes in animals, including humans. Hemoglobin is a protein found in red blood cells that contains a porphyrin ring with an iron atom at its center, which gives blood its red color and facilitates oxygen transport. Chlorophyll is a green pigment found in plants, algae, and some bacteria that absorbs light during photosynthesis to convert carbon dioxide and water into glucose and oxygen. Carotenoids are orange, yellow, or red pigments found in fruits, vegetables, and some animals that protect against oxidative stress and help maintain membrane fluidity. Flavonoids are a class of plant pigments with antioxidant properties that have been linked to various health benefits.

Food contamination is the presence of harmful microorganisms, chemicals, or foreign substances in food or water that can cause illness or injury to individuals who consume it. This can occur at any stage during production, processing, storage, or preparation of food, and can result from various sources such as:

1. Biological contamination: This includes the presence of harmful bacteria, viruses, parasites, or fungi that can cause foodborne illnesses. Examples include Salmonella, E. coli, Listeria, and norovirus.

2. Chemical contamination: This involves the introduction of hazardous chemicals into food, which may occur due to poor handling practices, improper storage, or exposure to environmental pollutants. Common sources of chemical contamination include pesticides, cleaning solvents, heavy metals, and natural toxins produced by certain plants or fungi.

3. Physical contamination: This refers to the presence of foreign objects in food, such as glass, plastic, hair, or insects, which can pose a choking hazard or introduce harmful substances into the body.

Preventing food contamination is crucial for ensuring food safety and protecting public health. Proper hygiene practices, temperature control, separation of raw and cooked foods, and regular inspections are essential measures to minimize the risk of food contamination.

Esters are organic compounds that are formed by the reaction between an alcohol and a carboxylic acid. They are widely found in nature and are used in various industries, including the production of perfumes, flavors, and pharmaceuticals. In the context of medical definitions, esters may be mentioned in relation to their use as excipients in medications or in discussions of organic chemistry and biochemistry. Esters can also be found in various natural substances such as fats and oils, which are triesters of glycerol and fatty acids.

Polyketide synthases (PKSs) are a type of large, multifunctional enzymes found in bacteria, fungi, and other organisms. They play a crucial role in the biosynthesis of polyketides, which are a diverse group of natural products with various biological activities, including antibiotic, antifungal, anticancer, and immunosuppressant properties.

PKSs are responsible for the assembly of polyketide chains by repetitively adding two-carbon units derived from acetyl-CoA or other extender units to a growing chain. The PKS enzymes can be classified into three types based on their domain organization and mechanism of action: type I, type II, and type III PKSs.

Type I PKSs are large, modular enzymes that contain multiple domains responsible for different steps in the polyketide biosynthesis process. These include acyltransferase (AT) domains that load extender units onto the PKS, acyl carrier proteins (ACPs) that tether the growing chain to the PKS, and ketosynthase (KS) domains that catalyze the condensation of the extender unit with the growing chain.

Type II PKSs are simpler enzymes that consist of several separate proteins that work together in a complex to synthesize polyketides. These include ketosynthase, acyltransferase, and acyl carrier protein domains, as well as other domains responsible for reducing or modifying the polyketide chain.

Type III PKSs are the simplest of the three types and consist of a single catalytic domain that is responsible for both loading extender units and catalyzing their condensation with the growing chain. These enzymes typically synthesize shorter polyketide chains, such as those found in certain plant hormones and pigments.

Overall, PKSs are important enzymes involved in the biosynthesis of a wide range of natural products with significant medical and industrial applications.

"Aspergillus" is a genus of filamentous fungi (molds) that are widely distributed in the environment. These molds are commonly found in decaying organic matter such as leaf litter, compost piles, and rotting vegetation. They can also be found in indoor environments like air conditioning systems, dust, and building materials.

The medical relevance of Aspergillus comes from the fact that some species can cause a range of diseases in humans, particularly in individuals with weakened immune systems or underlying lung conditions. The most common disease caused by Aspergillus is called aspergillosis, which can manifest as allergic reactions, lung infections (like pneumonia), and invasive infections that can spread to other parts of the body.

Aspergillus species produce small, airborne spores called conidia, which can be inhaled into the lungs and cause infection. The severity of aspergillosis depends on various factors, including the individual's immune status, the specific Aspergillus species involved, and the extent of fungal invasion in the body.

Common Aspergillus species that can cause human disease include A. fumigatus, A. flavus, A. niger, and A. terreus. Preventing exposure to Aspergillus spores and maintaining a healthy immune system are crucial steps in minimizing the risk of aspergillosis.

Food microbiology is the study of the microorganisms that are present in food, including bacteria, viruses, fungi, and parasites. This field examines how these microbes interact with food, how they affect its safety and quality, and how they can be controlled during food production, processing, storage, and preparation. Food microbiology also involves the development of methods for detecting and identifying pathogenic microorganisms in food, as well as studying the mechanisms of foodborne illnesses and developing strategies to prevent them. Additionally, it includes research on the beneficial microbes found in certain fermented foods and their potential applications in improving food quality and safety.

There is no medical definition for "dog diseases" as it is too broad a term. However, dogs can suffer from various health conditions and illnesses that are specific to their species or similar to those found in humans. Some common categories of dog diseases include:

1. Infectious Diseases: These are caused by viruses, bacteria, fungi, or parasites. Examples include distemper, parvovirus, kennel cough, Lyme disease, and heartworms.
2. Hereditary/Genetic Disorders: Some dogs may inherit certain genetic disorders from their parents. Examples include hip dysplasia, elbow dysplasia, progressive retinal atrophy (PRA), and degenerative myelopathy.
3. Age-Related Diseases: As dogs age, they become more susceptible to various health issues. Common age-related diseases in dogs include arthritis, dental disease, cancer, and cognitive dysfunction syndrome (CDS).
4. Nutritional Disorders: Malnutrition or improper feeding can lead to various health problems in dogs. Examples include obesity, malnutrition, and vitamin deficiencies.
5. Environmental Diseases: These are caused by exposure to environmental factors such as toxins, allergens, or extreme temperatures. Examples include heatstroke, frostbite, and toxicities from ingesting harmful substances.
6. Neurological Disorders: Dogs can suffer from various neurological conditions that affect their nervous system. Examples include epilepsy, intervertebral disc disease (IVDD), and vestibular disease.
7. Behavioral Disorders: Some dogs may develop behavioral issues due to various factors such as anxiety, fear, or aggression. Examples include separation anxiety, noise phobias, and resource guarding.

It's important to note that regular veterinary care, proper nutrition, exercise, and preventative measures can help reduce the risk of many dog diseases.

Ascomycota is a phylum in the kingdom Fungi, also known as sac fungi. This group includes both unicellular and multicellular organisms, such as yeasts, mold species, and morel mushrooms. Ascomycetes are characterized by their reproductive structures called ascus, which contain typically eight haploid spores produced sexually through a process called ascogony. Some members of this phylum have significant ecological and economic importance, as they can be decomposers, mutualistic symbionts, or plant pathogens causing various diseases. Examples include the baker's yeast Saccharomyces cerevisiae, ergot fungus Claviceps purpurea, and morel mushroom Morchella esculenta.

Fermentation is a metabolic process in which an organism converts carbohydrates into alcohol or organic acids using enzymes. In the absence of oxygen, certain bacteria, yeasts, and fungi convert sugars into carbon dioxide, hydrogen, and various end products, such as alcohol, lactic acid, or acetic acid. This process is commonly used in food production, such as in making bread, wine, and beer, as well as in industrial applications for the production of biofuels and chemicals.

Culture media is a substance that is used to support the growth of microorganisms or cells in an artificial environment, such as a petri dish or test tube. It typically contains nutrients and other factors that are necessary for the growth and survival of the organisms being cultured. There are many different types of culture media, each with its own specific formulation and intended use. Some common examples include blood agar, which is used to culture bacteria; Sabouraud dextrose agar, which is used to culture fungi; and Eagle's minimum essential medium, which is used to culture animal cells.

Fungal genes refer to the genetic material present in fungi, which are eukaryotic organisms that include microorganisms such as yeasts and molds, as well as larger organisms like mushrooms. The genetic material of fungi is composed of DNA, just like in other eukaryotes, and is organized into chromosomes located in the nucleus of the cell.

Fungal genes are segments of DNA that contain the information necessary to produce proteins and RNA molecules required for various cellular functions. These genes are transcribed into messenger RNA (mRNA) molecules, which are then translated into proteins by ribosomes in the cytoplasm.

Fungal genomes have been sequenced for many species, revealing a diverse range of genes that encode proteins involved in various cellular processes such as metabolism, signaling, and regulation. Comparative genomic analyses have also provided insights into the evolutionary relationships among different fungal lineages and have helped to identify unique genetic features that distinguish fungi from other eukaryotes.

Understanding fungal genes and their functions is essential for advancing our knowledge of fungal biology, as well as for developing new strategies to control fungal pathogens that can cause diseases in humans, animals, and plants.

Molecular structure, in the context of biochemistry and molecular biology, refers to the arrangement and organization of atoms and chemical bonds within a molecule. It describes the three-dimensional layout of the constituent elements, including their spatial relationships, bond lengths, and angles. Understanding molecular structure is crucial for elucidating the functions and reactivities of biological macromolecules such as proteins, nucleic acids, lipids, and carbohydrates. Various experimental techniques, like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy (cryo-EM), are employed to determine molecular structures at atomic resolution, providing valuable insights into their biological roles and potential therapeutic targets.

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