A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
A series of oxidative reactions in the breakdown of acetyl units derived from GLUCOSE; FATTY ACIDS; or AMINO ACIDS by means of tricarboxylic acid intermediates. The end products are CARBON DIOXIDE, water, and energy in the form of phosphate bonds.
An imperfect fungus causing smut or black mold of several fruits, vegetables, etc.
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
The ability to detect chemicals through gustatory receptors in the mouth, including those on the TONGUE; the PALATE; the PHARYNX; and the EPIGLOTTIS.
An enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+, Mn2+; it is activated by ADP, citrate, and Ca2+, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (From Dorland, 27th ed) (The NADP+ enzyme is EC 1.1.1.42.) EC 1.1.1.41.
Derivatives of OXALOACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include a 2-keto-1,4-carboxy aliphatic structure.
Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
An enzyme that catalyzes the reversible hydration of cis-aconitate to yield citrate or isocitrate. It is one of the citric acid cycle enzymes. EC 4.2.1.3.
The minimum concentration at which taste sensitivity to a particular substance or food can be perceived.
An order of fish including smelts, galaxiids, and salamanderfish.
A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)
An enzyme that catalyzes the reversible hydration of fumaric acid to yield L-malic acid. It is one of the citric acid cycle enzymes. EC 4.2.1.2.
Chemicals used mainly to disinfect root canals after pulpectomy and before obturation. The major ones are camphorated monochlorophenol, EDTA, formocresol, hydrogen peroxide, metacresylacetate, and sodium hypochlorite. Root canal irrigants include also rinsing solutions of distilled water, sodium chloride, etc.
Encysted cercaria which house the intermediate stages of trematode parasites in tissues of an intermediate host.
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Adherent debris produced when cutting the enamel or dentin in cavity preparation. It is about 1 micron thick and its composition reflects the underlying dentin, although different quantities and qualities of smear layer can be produced by the various instrumentation techniques. Its function is presumed to be protective, as it lowers dentin permeability. However, it masks the underlying dentin and interferes with attempts to bond dental material to the dentin.
Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.
A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
The process by which the nature and meaning of gustatory stimuli are recognized and interpreted by the brain. The four basic classes of taste perception are salty, sweet, bitter, and sour.
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
An enzyme that catalyzes the conversion of (S)-malate and NAD+ to oxaloacetate and NADH. EC 1.1.1.37.
Organic compounds containing the carboxy group (-COOH). This group of compounds includes amino acids and fatty acids. Carboxylic acids can be saturated, unsaturated, or aromatic.
Large bodies consisting of self-luminous gas held together by their own gravity. (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed)
Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane structure.
A nonreducing disaccharide composed of GLUCOSE and FRUCTOSE linked via their anomeric carbons. It is obtained commercially from SUGARCANE, sugar beet (BETA VULGARIS), and other plants and used extensively as a food and a sweetener.
A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.
Stable carbon atoms that have the same atomic number as the element carbon, but differ in atomic weight. C-13 is a stable carbon isotope.
A family of intestinal flukes of the class Trematoda which occurs in animals and man. Some of the genera are Heterophyes, Metagonimus, Cryptocotyle, Stellantchasmus, and Euryhelmis.
Compounds based on fumaric acid.
It is used as an oxidizing and bleaching agent and as a disinfectant. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Derivatives of acetic acid with one or more fluorines attached. They are almost odorless, difficult to detect chemically, and very stable. The acid itself, as well as the derivatives that are broken down in the body to the acid, are highly toxic substances, behaving as convulsant poisons with a delayed action. (From Miall's Dictionary of Chemistry, 5th ed)
Derivatives of SUCCINIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,4-carboxy terminated aliphatic structure.
Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.
A plant genus of the family RUTACEAE. They bear the familiar citrus fruits including oranges, grapefruit, lemons, and limes. There are many hybrids which makes the nomenclature confusing.
Enzymes that catalyze the first step leading to the oxidation of succinic acid by the reversible formation of succinyl-CoA from succinate and CoA with the concomitant cleavage of ATP to ADP (EC 6.2.1.5) or GTP to GDP (EC 6.2.1.4) and orthophosphate. Itaconate can act instead of succinate and ITP instead of GTP.EC 6.2.1.-.
A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.
A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
A ubiquitous sodium salt that is commonly used to season food.
A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
An enzyme that catalyzes the conversion of myo-inositol hexakisphosphate and water to 1L-myo-inositol 1,2,3,4,5-pentakisphosphate and orthophosphate. EC 3.1.3.26.
Chemical and physical transformation of the biogenic elements from their nucleosynthesis in stars to their incorporation and subsequent modification in planetary bodies and terrestrial biochemistry. It includes the mechanism of incorporation of biogenic elements into complex molecules and molecular systems, leading up to the origin of life.
Derivatives of GLUTAMIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the 2-aminopentanedioic acid structure.
Formation of stones in any part of the URINARY TRACT, usually in the KIDNEY; URINARY BLADDER; or the URETER.
Inorganic derivatives of phosphoric acid (H3PO4). Note that organic derivatives of phosphoric acids are listed under ORGANOPHOSPHATES.
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A species of gram-negative bacteria of the family ACETOBACTERACEAE found in FLOWERS and FRUIT. Cells are ellipsoidal to rod-shaped and straight or slightly curved.
A plant species of the family CLUSIACEAE. It is a source of hydroxycitric acid.
A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1.
Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.
Conditions characterized by an alteration in gustatory function or perception. Taste disorders are frequently associated with OLFACTION DISORDERS. Additional potential etiologies include METABOLIC DISEASES; DRUG TOXICITY; and taste pathway disorders (e.g., TASTE BUD diseases; FACIAL NERVE DISEASES; GLOSSOPHARYNGEAL NERVE DISEASES; and BRAIN STEM diseases).
The hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root, which is harder and denser than bone but softer than enamel, and is thus readily abraded when left unprotected. (From Jablonski, Dictionary of Dentistry, 1992)
The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)
A plant species of the genus CITRUS, family RUTACEAE that provides the familiar orange fruit which is also a source of orange oil.
Liquids that are suitable for drinking. (From Merriam Webster Collegiate Dictionary, 10th ed)
A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.
A powder that dissolves in water, which is administered orally, and is used as a diuretic, expectorant, systemic alkalizer, and electrolyte replenisher.
Salts and esters of the 7-carbon saturated monocarboxylic acid heptanoic acid.
Biosynthesis of GLUCOSE from nonhexose or non-carbohydrate precursors, such as LACTATE; PYRUVATE; ALANINE; and GLYCEROL.
Phosphorus used in foods or obtained from food. This element is a major intracellular component which plays an important role in many biochemical pathways relating to normal physiological functions. High concentrations of dietary phosphorus can cause nephrocalcinosis which is associated with impaired kidney function. Low concentrations of dietary phosphorus cause an increase in calcitriol in the blood and osteoporosis.
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Derivatives of OXALIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that are derived from the ethanedioic acid structure.
Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
The metabolic substances ACETONE; 3-HYDROXYBUTYRIC ACID; and acetoacetic acid (ACETOACETATES). They are produced in the liver and kidney during FATTY ACIDS oxidation and used as a source of energy by the heart, muscle and brain.
An important enzyme in the glyoxylic acid cycle which reversibly catalyzes the synthesis of L-malate from acetyl-CoA and glyoxylate. This enzyme was formerly listed as EC 4.1.3.2.
A branch of the facial (7th cranial) nerve which passes through the middle ear and continues through the petrotympanic fissure. The chorda tympani nerve carries taste sensation from the anterior two-thirds of the tongue and conveys parasympathetic efferents to the salivary glands.
The methyl esters of methacrylic acid that polymerize easily and are used as tissue cements, dental materials, and absorbent for biological substances.
A family of organic anion transporters that specifically transport DICARBOXYLIC ACIDS such as alpha-ketoglutaric acid across cellular membranes.
A tubular organ of VOICE production. It is located in the anterior neck, superior to the TRACHEA and inferior to the tongue and HYOID BONE.
An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.
A calcium salt that is used for a variety of purposes including: building materials, as a desiccant, in dentistry as an impression material, cast, or die, and in medicine for immobilizing casts and as a tablet excipient. It exists in various forms and states of hydration. Plaster of Paris is a mixture of powdered and heat-treated gypsum.
A condition characterized by an abnormally elevated concentration of KETONE BODIES in the blood (acetonemia) or urine (acetonuria). It is a sign of DIABETES COMPLICATION, starvation, alcoholism or a mitochondrial metabolic disturbance (e.g., MAPLE SYRUP URINE DISEASE).
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
A tooth's loss of minerals, such as calcium in hydroxyapatite from the tooth matrix, caused by acidic exposure. An example of the occurrence of demineralization is in the formation of dental caries.
An opioid analgesic related to MORPHINE but with less potent analgesic properties and mild sedative effects. It also acts centrally to suppress cough.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
Salts and derivatives of acetoacetic acid.
A genus of mitosporic fungi containing about 100 species and eleven different teleomorphs in the family Trichocomaceae.
The chemical reactions involved in the production and utilization of various forms of energy in cells.

Effect of shellfish calcium on the apparent absorption of calcium and bone metabolism in ovariectomized rats. (1/1204)

Fossil shellfish powder (FS) and Ezo giant scallop shell powder (EG) were rendered soluble with lactate and citrate under decompression (FSEx and EGEx, respectively) and we examined the effects of lactate-citrate solubilization of FS and EG on mineral absorption, tissue mineral contents, serum biochemical indices and bone mineral density (BMD) in ovariectomized (OVX) rats. The apparent absorption ratios of minerals tended to be high in the rats fed with the solubilized mineral sources, those in the FSEx group being significantly higher than in the FS group. There was no significant difference in the tibia mineral content among the OVX groups. BMD at the distal femoral diaphysis was significantly increased by FSEx and EGEx feeding. It is suggested that solubilization with lactate and citrate under decompression increased the solubility and bioavailability of calcium from such natural sources of shellfish calcium as FS and EG.  (+info)

Citric acid production from xylan and xylan hydrolysate by semi-solid culture of Aspergillus niger. (2/1204)

Citric acid production from xylan and xylan hydrolysate was done by Aspergillus niger Yang no. 2 cultivated in a semi-solid culture using bagasse as a carrier. Yang no. 2 produced 72.4 g/l and 52.6 g/l of citric acid in 5 d from 140 g/l of xylose and arabinose, respectively. Yang no. 2 produced 51.6 g/l of citric acid in 3 d from a concentrated xylan hydrolysate prepared by cellulase treatment, containing 100 g/l of reducing sugars. Moreover, Yang no. 2 directly produced 39.6 g/l of citric acid maximally in 3 d from 140 g/l of xylan.  (+info)

Down regulation by iron of prostaglandin E2 production by human synovial fibroblasts. (3/1204)

OBJECTIVE: To examine the effect of iron on the prostaglandin (PG) E2 production by human synovial fibroblasts in vitro. METHODS: Human synovial fibroblasts were isolated from synovial tissue of rheumatoid arthritis (RA) and osteoarthritis (OA) patients and cultured in medium. Synovial fibroblasts were stimulated by human recombinant interleukin (IL) 1 beta (0.1-10 ng/ml) with or without ferric citrate (Fe-citrate, 0.01-1 mM). The amount of PGE2 in the culture medium was measured by an enzyme linked immunosorbent assay. RESULTS: The production of PGE2 by the synovial fibroblasts was increased by stimulation with IL1 beta at all concentrations tested. Fe-citrate but not sodium citrate (Na-citrate) down regulated the production of PGE2 by the synovial fibroblasts, both with and without stimulation by IL1 beta. Fe-citrate inhibited the spontaneous PGE2 production by the cells in a dose dependent manner, and a maximum inhibition by Fe-citrate was observed at the concentration of 0.1 mM with IL1 beta stimulation. The down regulation by iron was reversed by the co-addition of desferrioxamine (100 micrograms/ml), an iron chelator. CONCLUSION: Iron down regulates the PGE2 production by synovial fibroblasts in vitro.  (+info)

Roles of oxygen radicals and elastase in citric acid-induced airway constriction of guinea-pigs. (4/1204)

Antioxidants attenuate noncholinergic airway constriction. To further investigate the relationship between tachykinin-mediated airway constriction and oxygen radicals, we explored citric acid-induced bronchial constriction in 48 young Hartley strain guinea-pigs, divided into six groups: control; citric acid; hexa(sulphobutyl)fullerenes + citric acid; hexa(sulphobutyl)fullerenes + phosphoramidon + citric acid; dimethylthiourea (DMTU) + citric acid; and DMTU + phosphoramidon + citric acid. Hexa(sulphobutyl)fullerenes and DMTU are scavengers of oxygen radicals while phosphoramidon is an inhibitor of the major degradation enzyme for tachykinins. Animals were anaesthetized, paralyzed, and artificially ventilated. Each animal was given 50 breaths of 4 ml saline or citric acid aerosol. We measured dynamic respiratory compliance (Crs), forced expiratory volume in 0.1 (FEV0.1), and maximal expiratory flow at 30% total lung capacity (Vmax30) to evaluate the degree of airway constriction. Citric acid, but not saline, aerosol inhalation caused marked decreases in Crs, FEV0.1 and Vmax30, indicating marked airway constriction. This constriction was significantly attenuated by either hexa(sulphobutyl)fullerenes or by DMTU. In addition, phosphoramidon significantly reversed the attenuating action of hexa(sulphobutyl)fullerenes, but not that of DMTU. Citric acid aerosol inhalation caused increases in both lucigenin- and t-butyl hydroperoxide-initiated chemiluminescence counts, indicating citric acid-induced increase in oxygen radicals and decrease in antioxidants in bronchoalveolar lavage fluid. These alterations were significantly suppressed by either hexa(sulphobutyl)fullerenes or DMTU. An elastase inhibitor eglin-c also significantly attenuated citric acid-induced airway constriction, indicating the contributing role of elastase in this type of constriction. We conclude that both oxygen radicals and elastase play an important role in tachykinin-mediated, citric acid-induced airway constriction.  (+info)

Citrate ions enhance taste responses to amino acids in the largemouth bass. (5/1204)

The glossopharyngeal (IX) taste system of the largemouth bass, Micropterus salmoides, is highly selective to amino acids and is poorly responsive to trisodium citrate; however, IX taste responses to specific concentrations of L- and D-arginine and L-lysine but not L-proline were enhanced by citrate but not sodium ions. Binary mixtures of L-arginine (3 x 10(-4)M and 10(-3)M) or D-arginine (10(-3)M) + trisodium citrate (10(-3)M; pH 7-9) resulted in enhanced taste activity, whereas binary mixtures of higher concentrations (10(-2)M and 10(-1)M) of L- or D-arginine + 10(-3)M trisodium citrate were not significantly different from the response to the amino acid alone. Under continuous adaptation to 10(-3)M citrate, taste responses to L-arginine were also enhanced at the identical concentrations previously indicated, but responses to 10(-2)M and 10(-1)M L-arginine were significantly suppressed. Under continuous adaptation to 10(-2)M L-arginine, taste responses to 10(-2)M, 10(-1)M, and 10(0) M citrate were significantly enhanced. Cellular concentrations of both citrate and amino acids in prey of the carnivorous largemouth bass are sufficient for this taste-enhancing effect to occur naturally during consummatory feeding behavior. Citrate acting as a calcium chelator is presented as a possible mechanism of action for the enhancement effect.  (+info)

Trophoblast cell line resistance to NK lysis mainly involves an HLA class I-independent mechanism. (6/1204)

The lack of classical HLA molecules on trophoblast prevents allorecognition by maternal T lymphocytes, but poses the problem of susceptibility to NK lysis. Expression of the nonclassical class I molecule, HLA-G, on cytotrophoblast may provide the protective effect. However, the class I-negative syncytiotrophoblast escapes NK lysis by maternal PBL. In addition, while HLA-G-expressing transfectants of LCL.721.221 cells are protected from lymphokine-activated killer lysis, extravillous cytotrophoblast cells and HLA-G-expressing choriocarcinoma cells (CC) are not. The aim of this work was therefore to clarify the role of HLA class I expression on trophoblast cell resistance to NK lysis and on their susceptibility to lymphokine-activated killer lysis. Our results showed that both JAR (HLA class I-negative) and JEG-3 (HLA-G- and HLA-Cw4-positive) cells were resistant to NK lysis by PBL and were equally lysed by IL-2-stimulated PBL isolated from a given donor. In agreement, down-regulating HLA class I expression on JEG-3 cells by acid treatment, masking these molecules or the putative HLA-G (or HLA-E) receptor CD94/NKG2 and the CD158a/p58.1 NKR with mAbs, and inducing self class I molecule expression on JAR cells did not affect NK or LAK lysis of CC. These results demonstrate that the resistance of CC to NK lysis mainly involves an HLA class I-independent mechanism(s). In addition, we show that the expression of a classical class I target molecule (HLA-B7) on JAR cells is insufficient to induce lysis by allospecific polyclonal CTL.  (+info)

Regional citrate anticoagulation in continuous venovenous hemofiltration in critically ill patients with a high risk of bleeding. (7/1204)

BACKGROUND: Systemic heparinization is associated with a high rate of bleeding when used to maintain patency of the extracorporeal circuit during continuous renal replacement therapy (CRRT) in critically ill patients. Regional anticoagulation can be achieved with citrate, but previously described techniques are cumbersome and associated with metabolic complications. METHODS: We designed a simplified system for delivering regional citrate anticoagulation during continuous venovenous hemofiltration (CVVH). We evaluated filter life and hemorrhagic complications in the first 17 consecutive patients who received this therapy at our institution. Blood flow rate was set at 180 ml/min. Ultrafiltration rate was maintained at 2.0 liters/hr and citrate-based replacement fluid (trisodium citrate 13.3 mM, sodium chloride 100 mM, magnesium chloride 0.75 mM, dextrose 0.2%) was infused proximal to the filter to maintain the desired fluid balance. Calcium gluconate was infused through a separate line to maintain a serum-ionized calcium level of 1.0 to 1.1 mM. RESULTS: All patients were critically ill and required mechanical ventilation and vasopressor therapy. Systemic heparin anticoagulation was judged to be contraindicated in all of the patients. A total of 85 filters were used, of which 64 were lost because of clotting, with a mean life span of 29.5 +/- 17.9 hours. The remaining 21 filters were discontinued for other reasons. Control of fluid and electrolyte balance and azotemia was excellent (mean serum creatinine after 48 to 72 hr of treatment was 2.4 +/- 1.2 mg/dl). No bleeding episodes occurred. Two patients, one with septic shock and the other with fulminant hepatic failure, developed evidence for citrate toxicity without a significant alteration in clinical status. Nine patients survived (52.9%). CONCLUSION: Our simplified technique of regional anticoagulation with citrate is an effective and safe form of anticoagulation for CVVH in critically ill patients with a high risk of bleeding.  (+info)

Comparative absorption of calcium sources and calcium citrate malate for the prevention of osteoporosis. (8/1204)

Anthropologically speaking, humans were high consumers of calcium until the onset of the Agricultural Age, 10,000 years ago. Current calcium intake is one-quarter to one-third that of our evolutionary diet and, if we are genetically identical to the Late Paleolithic Homo sapiens, we may be consuming a calcium-deficient diet our bodies cannot adjust to by physiologic mechanisms. Meta-analyses of calcium and bone mass studies demonstrate supplementation of 500 to 1500 mg calcium daily improves bone mass in adolescents, young adults, older men, and postmenopausal women. Calcium citrate malate has high bioavailability and thus has been the subject of calcium studies in these populations. Positive effects have been seen in prepubertal girls, adolescents, and postmenopausal women. The addition of trace minerals and vitamin D in separate trials has improved the effect of calcium citrate malate on bone density and shown a reduction of fracture risk.  (+info)

Citric acid is found naturally in citrus fruits, but producing citric acid from citrus fruits is very expensive and the demand for citric acid is greater than the available supply of citrus fruits. Therefore, when you see citric acid on a product label, you can be sure that it is a powder that was made from the fermentation of sugars. A culture of Aspergillus niger (a fungus commonly used in the pharmaceutical industry) is fed with sugar and metabolizes it into a liquid solution. The solution is mixed with lime (calcium hydroxide) which causes citrate salt to come out of the solution (precipitate). The citrate salt is then treated with sulfuric acid to make useable citric acid.. The sugars that are used for the citric acid can be derived from cane sugar, corn or wheat. In the United States, citric acid is most often derived from corn since it is a cheap, subsidized crop. In South America cane sugar is often used due to the low sugar prices, while in Europe wheat sweeteners are commonly ...
I prepared a bottle of "50%" citric acid solution using a suggested method of filling a bottle halfway by volume then filling the rest with water. I filled a...
Citric acid is traditionally produced by fermentation of molds since the beginning of the 20th century. However, its overall demand continually increases due to its very widespread applications ranging from traditional food use to more specific pharmaceutical and more recent biopolymer uses.. Therefore the production of citric acid is also continually improved involving the most recent tools and techniques of the field. This book discusses the metabolism of citric acid production by Aspergillus niger; biotechnological productions of citric acid; citrus fruits compounds and aging; occurrence and metabolism of citric acid by lactic acid bacteria from fruits and fermented beverages; and citric acid treatment of cancer. (Imprint: Novinka ). ...
Citric acid -- a naturally occurring compound in citrus fruits such as oranges, lemons and grapefruit -- boasts several properties that may make it useful as either a treatment for certain medical conditions or as a dietary supplement. Citric acid is an alkalizing agent: It is able to decrease the level of acidity in body fluids. It acts as an anti-oxidant and is also able to chelate -- binding to excess calcium and allowing it to leave the body. Despite its documented health benefits, you should not take citric acid supplements without first consulting your physician.. Anti-oxidant Benefits. As an anti-oxidant, citric acid may be able to neutralize the damaging effects of free radicals, unstable compounds that can accumulate in the body from exposure to toxic chemicals, smoking and even normal cell metabolism. Free radicals can damage cell tissue and DNA and increase the risk of developing cardiovascular disease, Alzheimers disease and cancer. The Mayo Clinic website reports that citric acids ...
Citric acid exists in greater than trace amounts in a variety of fruits and vegetables, most notably citrus fruits. Lemons and limes have particularly high concentrations of the acid; it can constitute as much as 8% of the dry weight of these fruits (about 47 g/l in the juices[9]).[a] The concentrations of citric acid in citrus fruits range from 0.005 mol/L for oranges and grapefruits to 0.30 mol/L in lemons and limes; these values vary within species depending upon the cultivar and the circumstances in which the fruit was grown. Industrial-scale citric acid production first began in 1890 based on the Italian citrus fruit industry, where the juice was treated with hydrated lime (calcium hydroxide) to precipitate calcium citrate, which was isolated and converted back to the acid using diluted sulfuric acid.[10] In 1893, C. Wehmer discovered Penicillium mold could produce citric acid from sugar. However, microbial production of citric acid did not become industrially important until World War I ...
Any non-trial optimisation design could only be accomplished from a consistent picture of the mycelial physiology. In this work, we have made progress on the understanding of the biochemical basis of the citric acid producing strain of Aspergillus niger using afed-batch cultivation system. This optimisation would imply the improvement of both, the citric acid synthesis and excretion rate. For citric acid fermentation, trace elements such as copper, managanese, iron, zinc and molybdenum are needed in ppm for optimum growth (Netik et al. 1997), but the concentration will depend on the carbon source used and temperature of incubation. The data in Table 1 show the screening of the best available stock cultures of Aspergillus niger for citric acid production in an agitator bioreactor. The range of citric acid was 54.50-87.98 g/l. The culture NGGCB101 (developed by UV/Chemical mutation in our labs) gave maximum yield of the product (87.98 g/l) followed by Zowang-12 (84.20 g/l) and NIAB-280 (79.40 ...
In this study, a glycerol which is a common biodiesel byproduct was used to produce citric acid by fermentation using strains of Aspergillus niger. The culture medium contained glycerol as the carbon source, yeast extract as the nitrogen source and KHzP04 and Na2HP04 as the phosphate source as well as other essential nutrients for the fungae. The parameters studied were incubation temperature, nitrogen content, phosphate content and addition of additive. Eight experiments were done to determine the most optimum conditions. Titration of the product citric acid with 0.1 M NaOH was done to obtain the concentration and yield of citric acid of all experiments. The result obtained proved that citric acid production was most optimum when the incubation temperature was at 30°C, nitrogen contents at 0.01 to 0.04 g per 100 m1 and the phosphate content at 0.7 g per 100ml. Also when ethanol at 3.0 % v/w was used as an additive in the medium the yield of citric acid increased. Experiment eight with the ...
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A method of treating blood withdrawn from patient including: simultaneously withdrawing blood and infusing withdrawn blood from and to the patient by flowing the withdrawn blood through an extracorporeal dialysis circuit including a dialyzer having a semi-permeable dialysis membrane and a dialysate side adjacent the membrane; feeding a dialysate containing 1 to 5 mM total calcium and 2 to 8 mM citrate to the dialysate side of the dialyzer, and introducing an anticoagulation fluid including at least 8 mM citrate into the arterial blood line.
https://youtu.be/eFqChtPhBNw Suggested Use: 1-4 capsules per day, in divided doses, with meals Magnesium (citrate/malate) - This vital mineral is a imperati
Citric acid (citrate) is a weak acid that is formed in the tricarboxylic acid cycle or that may be introduced with diet. The evaluation of plasma citric acid is scarcely used in the diagnosis of animal diseases. On the contrary urinary citrate excretion is a common tool in the differential diagnosis of kidney stones, renal tubular acidosis and it plays also a role in bone diseases. The importance of hypocitraturia should be considered with regard to bone mass, urine crystallization and urolithiasis. (PMID 12957820 ) The secretory epithelial cells of the prostate gland of animals and other animals posses a unique citrate-related metabolic pathway regulated by testosterone and prolactin. This specialized hormone-regulated metabolic activity is responsible for the major prostate function of the production and secretion of extraordinarily high levels of citrate. The key regulatory enzymes directly associated with citrate production in the prostate cells are mitochondrial aspartate aminotransferase, ...
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The present study examined whether infants show an acceptance for extreme sour tastes and whether acceptance of sour taste is related to infants fruit intake. Fruit intake of fifty-three infants at 6, 12 and 18 months was assessed using 3 d food records. Sour acceptance of these infants was studied at 18·1 (sd1·5) months. Acceptance for four solutions differing in citric acid concentrations (0·00 m, 0·013 m, 0·029 m and 0·065 m) was measured by allowing infants ad libitum ingestion of each solution over brief time periods. The base solution to which citric acid was added was blackcurrant squash diluted in water. Infants relative intake of each solution was used as a measure of sour acceptance. At 18 months, twelve infants readily accepted the two highest citric acid concentrations, whereas the remaining infants rejected these. Infants who accepted the most sour solutions had a significantly higher fruit intake (P = 0·025) and a higher fruit variety (P = 0·015) at 18 months than the ...
Citric acid crystals. Polarized light micrograph of a section through crystals of citric acid (tricarboxylic acid). Citric acid can be obtained from natural products such as the juices of citric fruits e.g.. lemons. It is also obtained by fermentation of glucose (citric acid cycle) and by synthesis. Magnification: x200 when printed at 10 centimetres tall. - Stock Image C026/2620
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Summary The mass transfer process during the reaction of citric acid with calcite was investigated using a rotating disk apparatus. The effects of disk rotational speed, initial citric acid concentration and temperature on the effective diffusion co
Magnesium (citrate) Highly absorbable magnesium chelate Magnesium activates the enzymes necessary for a number of physiological functions, including neuromuscular contractions, cardiac function, and the regulation of the acid- alkaline balance in the body. It is necessary for the metabolism of carbohydrates, amino acids and fats; also for energy production, and the utilization of calcium, phosphorus, sodium, and potassium. This vital mineral also helps utilize B-complex vitamins, vitamin C, and vitamin E. Magnesium in aspartate, citrate, citrate/malate, and glycinate forms are highly bioavailable magnesium chelates, supporting the metabolism and utilization of many essential nutrients and the proper functioning of important enzymatic and physiological functions. Supplement Facts: Amount Per Serving each vegetable capsule contains: magnesium (citrate) 150 mg. vitamin C (as ascorbyl palmitate) 11 mg. Directions: 1-4 capsules per day, in divided doses, with meals., with meals.
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In this study we investigated the transcriptional role of the sterol regulatory element (SRE) present in the promoter of the mitochondrial citrate carrier (CIC). We show that wild-type (but not mutated) CIC SRE cloned in front of the luciferase promoter confers transcriptional activation of the gene reporter. We also demonstrate that insulin activates, and polyunsaturated fatty acids (PUFA) inhibit, the gene reporter activity driven by the CIC promoter containing wild-type (but not mutated) SRE. Finally, both insulin treatment and overexpression of SRE binding protein (SREBP-1) increase the CIC transcript and protein levels, whereas PUFA have an opposite effect. These results show that SRE/SREBP-1 play a role in the transcriptional regulation of CIC by insulin and PUF. ...
AS 3 - dextrose monohydrate, sodium citrate, sodium chloride, sodium phosphate, monobasic, monohydrate, citric acid monohydrate and adenine injection, solution - Prescription (RX) Marketed Drugs Encyclopedia
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Could someone be able to elaborate more for me in regards to what Citric Acid is please? Is it from citric fruits or from animals? I am noticing that Citric Acid is in fruit lollies which are a natural lolly so Im presuming its from a lemon, orange or grapefruit and Citric Acid is also in Vegetable can soups where all vegetables are in it. I find this acid is be somewhat confusing :faint_smilie:
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The positive results obtained with regional citrate anticoagulation were confirmed in 3 recently published large studies involving 251 patients (9,31,38). In the prospective randomized study by Kutsogiannis DJ et al (38) involving 30 patients not at high risk of hemorrhagic complications, the median hemofilter survival time was 124.5 hours in the citrate group, the time being significantly longer than the 38.3 hours in the heparin group (P , 0.001). As regards adverse effects, no definite hemorrhage occurred in the citrate group whereas seven instances did in the heparin group. Occult hemorrhage was once present in both the citrate and heparin group. After adjustment for antithrombin-III levels and illness severity score, the relative risk of hemorrhage with citrate anticoagulation was still significantly lower than that with heparin (0.14 vs 0.96). In the second considered large multi-center study involving seven US centers, 138 patients and 442 CRRT circuits were utilized to assess filter life ...
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Water was introduced into a reverse osmosis unit, passing through a semipermeable membrane to remove impurities and producing deionized water. Anhydrous 99% pure citric acid was mixed with the water to produce 200 gallons of a 20 % (wtA-ol) (796 g citric acid per gallon water) solution. The 200 gallons of 20% citric acid were directed into an ion chamber containing having positive and negative electrodes, each consisting of 200 troy ounces of 999 fine silver. The positive and negative electrodes were spaced at least 2.0 mm apart, allowing the citric acid solution to pass between the two electrodes. An ion generation controller (IGC) power supply including a positive and a negative conductor was attached to the positive and negative electrodes. The IGC applied a current of 5 amps at 17 volts, pulsed every 9 seconds, with a polarity change at 1 minute intervals. Throughout the process, the electrode gap was adjusted in order to maintain the 5 amp-17 volt output. The electric current flow caused an ...
The cleaning instructions for the SMS equipment generally also apply for the sterilizer. However, the following exceptions are to be observed:. Do not use detergent containing acid. Sensors, heaters, etc. should not be cleaned with detergents but can be disinfected according to the current standard. Specifically heaters where applicable are to be cleaned periodically for lime using acetic or citric acid according to the mixing ratio and instructions stated on the product. Do not use acetic or citric acid on any other part of the sterilizer, especially not plastic components such as e.g. the lid. Under no circumstances, will these parts stand the influence of acetic or citric acid. Use a cloth when applying the acid on the heater.. Note: Use protection equipment such as gloves and waterproof clothes. Rinse off with large amounts of water. Application time is given by the instructions on the product in question.. ...
Tate & Lyle will cease production of citric acid at is UK plant at the end of the month following the completion of an employee consultation process.
Magnesium, like calcium, is an essential bone matrix mineral that promotes healthy bone metabolism. Supplementation with calcium and magnesium provides synergistic support for bone health. Magnesium also supports cardiovascular health by helping to mainta...
Citric acid is a kind of important organic acid, also known as folic acid, colorless crystals, often contain a molecular crystal water, odourless, has a strong acid, soluble in water. The calcium salt easy dissolve in cold water than hot water, and the properties of commonly used to identify and separate citric acid ...
Citric acid is soluble in water to a great degree. In water of a temperature of 212 degrees Fahrenheit, 84 percent of the citric acid added to the solution is...
MountainRoseHerbs.com, Brambleberry.com and Amazon.com sell citric acid, offering a variety of size options from 1 pound to 55 pound bags, as of June 2015. People use citric acid for cooking,...
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The report presents a highly comprehensive and accurate research study on the global Citric Acid market. It offers PESTLE analysis, qualitative and quantitative analysis, Porters Five Forces analysis, and absolute dollar opportunity analysis to help players improve their business strategies. It also sheds light on critical market dynamics such as trends and opportunities, drivers, restraints, and challenges to help market participants stay informed and cement a strong position in the industry. With competitive landscape analysis, the authors of the report have made a brilliant attempt to help readers understand important business tactics that leading companies use to maintain market sustainability.. Report Includes Major Key-Players of Citric Acid Market: Weifang Ensign Industry Co., Ltd., TTCA Co., Ltd. Get a Sample PDF Copy of this Report @ https://www.qyresearch.com/sample-form/form/1089859/global-citric-acid-market. The regional analysis section of the report allows players to concentrate ...
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Dri-Pak Citric Acid is a natural descaler. Citric Acid is a limescale remover, containing natural acid which is commonly found in citrus fruits.
The global Citric Acid market is segmented by company, region (country), by Type, and by Application. Players, stakeholders, and other participants in the global Citric Acid market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on sales, revenue and forecast by region (country), by Type and by Application for the period 2016-2027.. ...
Citric acid levels of at least 4 g/L (400 micrograms in a 0.1 mL sample) do not interfere with the D-Isocitric Acid Assay Kit , even higher levels of isocitric acid:citric acid ratios of 1:10 can be tolerated.. ...
Citric acid levels of at least 4 g/L (400 micrograms in a 0.1 mL sample) do not interfere with the D-Isocitric Acid Assay Kit , even higher levels of isocitric acid:citric acid ratios of 1:10 can be tolerated.. ...
China Citric Acid Market and ProductionAs the natural acid, citric acid industry has seen a fast growth in China before 2008 due to increasingdemand from both …
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In this series, blood and urinary tests confirmed the usual features of FHHNC (15) in CLDN19 patients: (1) persistent hypomagnesemia unresponsive to Mg2+ administration, (2) thiazide-sensitive hypercalciuria with normal serum Ca2+ levels and a slightly increased parathormone level, (3) low urinary citrate excretion, and (4) progressive renal failure leading to ESRD. However, one can note some peculiar renal findings. First, although FHHNC is mostly diagnosed during the first years of life (age of diagnosis within the first decade for all patients, within the first year of life for 8 of 12 patients) (5), it can be asymptomatic until the end of the second decade as exemplified by patient F2.3. In patients with CLDN16-related FHHNC, a genotype-phenotype correlation has been established and age at onset and severity may be predicted from the CLDN16 genotype (12). Because of the recent recognition of CLDN19 mutations in humans and their low frequency, this analysis has not yet been performed in ...
Hi, Ive been searching for a liquid carbon, other than glut based products, and I found other liquid carbon sources based on citrate and citric acid....
Calcium citrate malate is a water-soluble calcium supplement. It is the calcium salt of citric acid and malic acid with variable composition. Calcium citrate malates bioavailability stems from its water-solubility and its method of dissolution. When dissolved, it releases calcium ions and a calcium citrate complex. Calcium ions are absorbed directly into intestinal cells, and the citrate complex enters the body through paracellular absorption.[citation needed] Calcium citrate malate is similar to calcium malate and other calcium salts. The European Food Safety Authority has concluded that calcium citrate malate is slightly more bioavailable than other forms of calcium supplementation. Calcium citrate malate at Jost Chemical Calcium citrate malate as source for calcium for use in foods for Particular Nutritional Uses and in foods for the general population (including food supplements) (PDF). The EFSA Journal. 612: 1-24. 2007. doi:10.2903/j.efsa.2007.612Scientific Opinion of the Panel on Food ...
THE EFFECT OF ADDING SUGAR AND CITRIC ACID ON THE ANTIOXIDANT ACTIVITY AND REHYDRATION TIME OF WHITE SAFFRON (Curcuma mangga Val.) INSTANT POWDER
Pioneer Herbal is manufacturer of Calcium Citrate Malate (Light) which is a white powder. Natural Herbal Extracts of Calcium Citrate Malate (Light) available
Calcium (citrate/malate) 150 mg promotes calcium absorption and healthy teeth* supports healthy cardiovascular function* maintains emotional wellness in mild PMS* Calcium (citrate/malate) is necessary for healthy teeth and bones.* Calcium is essential to many physiological functions, such as maintaining healthy heart f
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TY - JOUR. T1 - Expression analysis of alternative oxidase gene (aox1) with enhanced green fluorescent protein as marker in citric acid-producing Aspergillus niger. AU - Kirimura, Kohtaro. AU - Ogawa, Satoshi. AU - Hattori, Takasumi. AU - Kino, Kuniki. N1 - Funding Information: We express our thanks to Dr. Y. Niwa of the University of Shizuoka and Professor K. Kitamoto of the University of Tokyo for supplying the plasmid pBEGFP-F harboring the egfp gene. This work was partly supported by the 21COE program Practical Nano-Chemistry from MEXT, Japan.. PY - 2006/9. Y1 - 2006/9. N2 - In a citric acid-producing filamentous fungus Aspergillus niger WU-2223L, a cyanide- and antimycin A-insensitive and salicylhydroxamic acid-sensitive respiratory pathway functions in the mitochondria besides the cytochrome pathway and is catalyzed by alternative oxidase (AOX). We constructed an A. niger transformant strain AOXEGFP-1 expressing a fusion gene, aox1-egfp, encoding AOX and enhanced green fluorescent ...
Lead citrate is a key precursor for the green recycling of spent lead acid battery paste in a citric acid/sodium citrate (CA/SC) solution. In this study, the main paste component, PbSO4, was leached and crystallized to yield lead citrate. Results showed that the leaching of PbSO4 in citric acid/sodium citrate solution was remarkably enhanced by an increase in temperature from 35 °C to 95 °C and an increase in sodium citrate (SC) concentration from 50 to 650 g/L. In comparison, increasing the citric acid/sodium citrate molar ratio inhibited this leaching. Controlled crystallization through cooling the solution or adjusting the pH of the solution can effectively produce lead citrate crystals. The X-ray diffraction patterns of four products obtained in a comparison test were all consistent with Pb3(C6H5O7)2. However, the scanning electron microscopy analysis suggested that the morphology was distinct from rods to sheets, which were mainly affected by the temperature variation.
Easy to read patient leaflet for Potassium Citrate and Citric Acid Solution. Includes indications, proper use, special instructions, precautions, and possible side effects.
Headline: Bitcoin & Blockchain Searches Exceed Trump! Blockchain Stocks Are Next!. In depth analysis of Magnesium Citrate Market is a crucial thing for various stakeholders like investors, CEOs, traders, suppliers and others. The Magnesium Citrate Market research report is a resource, which provides technical and financial details of the Magnesium Citrate industry.. Browse detailed TOC, Tables, Figures, Charts and Companies Mentioned in Magnesium Citrate Research Report @ http://www.360marketupdates.com/global-magnesium-citrate-market-research-report-2016-10334480. To begin with, the report elaborates the Magnesium Citrate market overview. Various definitions and classification of the industry, applications of the industry and chain structure are given. Present day status of the Magnesium Citrate market in key regions is stated and industry policies and news are analysed.. Next part of the Magnesium Citrate market analysis report speaks about the manufacturing process. The process is analysed ...
The superior ability of citrate excretion in a carrot (Daucus carota L.) mutant cell line, namely IPG (insoluble phosphate grower) [Takita et al. (1999a) Plant Cell Physiol. 40: 489] cells has been characterized in terms of citrate transport at the plasma membrane. IPG cells released about a 20-fold increase in citrate in comparison with malate, while the concentration of malate was only 35% lower than that of citrate in the cell sap. Citrate excretion was sensitive to anion channel blockers, such as niflumic acid and anthracene-9-carboxylic acid. These results indicate that IPG cells release citrate through the plasma membrane using citrate specific anion channels. The rate of citrate release from IPG cells was not affected by the concentration of aluminum (0 and 50 µM), soluble Pi (0 or 2 mM) and the pH (4.5-5.6) of the medium, suggesting that anion channels would not be regulated by such external conditions. Citrate excretion correlated with the H+ efflux, possibly from the action of ...
TY - JOUR. T1 - Citrate anticoagulation during CVVH in high risk bleeding patients. AU - Cubattoli, Lucia. AU - Teruzzi, M.. AU - Cormio, M.. AU - Lampati, L.. AU - Pesenti, A.. PY - 2007/3. Y1 - 2007/3. N2 - Background: Regional citrate anticoagulation (RCA) is an effective form of anticoagulation for continuous renal replacement therapy (CRRT) in patients with contraindications to heparin. Its use has been very limited, possibly because of the need for special infusion solutions and difficult monitoring of the metabolic effects. Objective: To investigate the safety and the feasibility of an RCA method for continuous veno-venous hemofiltration (CVVH) using commercially available replacement fluid. Methods: We evaluated 11 patients at high risk of bleeding, requiring CVVH. RCA was performed using commercially available replacement fluid solutions to maintain adequate acid-base balance. We adjusted the rate of citrate infusion to achieve a post-filter ionized calcium concentration [iCa] 250 ...
The citrate-induced desorption kinetics of pre-adsorbed Se from montmorillonite (Mt) and its complexes with hydroxyaluminum (HyA-Mt) and hydroxyaluminosilicate (HAS-Mt) were studied. The mole fraction of pre-adsorbed Se released in 24 h from different clays followed the trends of Mt ,, HAS-Mt , HyA-Mt with a significant increase with elevated citrate concentration in the desorbing solution. In contrast, the amount of Se adsorbed per unit mass of different clays followed a clear-cut opposite trend of HyA-Mt , HAS-Mt ,, Mt. The Se desorption kinetics in different systems indicated multiple rate characteristics; where an initial fast reaction (0.25-2 h) was followed by a slow reaction (2-16 h). Of the six different kinetic models tested (zero-, first-, and second-order; power function, Elovich, and parabolic diffusion), the second-order rate equation showed the overall best fit to the fast and slow desorption kinetic data from the clays. Based on second-order rate constants, the rates of the mole ...
BACKGROUND AND PURPOSE: Hypocitraturia, an important risk factor for calcium oxalate nephrolithiasis, is the result of numerous factors. We studied citrate excretion by patients with and without stones consuming normal and controlled formula diets. S
Calcium Citrate Malate is a readily-soluble form of calcium which is an easily absorbed and well-tolerated form of calcium. Calcium is an essential mineral required for healthy bone formation. Calcium bound to natural fruit acids called citric acid and malic acid results in the calcium compound, Calcium Citrate Malate. This form of calcium has been shown to have a superior benefit compared to many calcium supplements as it allows for 40% more calcium absorption than calcium carbonate or milk. Calcium Citrate Malate is easily digested and absorbed equally well with or without food.. Calcium is the basic bone-building mineral required by the body. Adequate calcium intake every day, over a lifetime, is important for maintaining sufficient bone density as we age and reducing risk for osteoporosis, a progressive bone disease leading to fragile, porous bones. Risk for osteoporosis is also influenced by age, sex, race, exercise, and many other dietary and lifestyle choices. Calcium Citrate Malate is ...
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Citric acid (citrate) is a weak acid that is formed in the tricarboxylic acid cycle or that may be introduced with diet. The evaluation of plasma citric acid is scarcely used in the diagnosis of human diseases. On the contrary urinary citrate excretion is a common tool in the differential diagnosis of kidney stones, renal tubular acidosis and it plays also a role in bone diseases. The importance of hypocitraturia should be considered with regard to bone mass, urine crystallization and urolithiasis. (PMID 12957820 ) The secretory epithelial cells of the prostate gland of humans and other animals posses a unique citrate-related metabolic pathway regulated by testosterone and prolactin. This specialized hormone-regulated metabolic activity is responsible for the major prostate function of the production and secretion of extraordinarily high levels of citrate. The key regulatory enzymes directly associated with citrate production in the prostate cells are mitochondrial aspartate aminotransferase, ...
Citric acid (citrate) is a weak acid that is formed in the tricarboxylic acid cycle or that may be introduced with diet. The evaluation of plasma citric acid is scarcely used in the diagnosis of human diseases. On the contrary urinary citrate excretion is a common tool in the differential diagnosis of kidney stones, renal tubular acidosis and it plays also a role in bone diseases. The importance of hypocitraturia should be considered with regard to bone mass, urine crystallization and urolithiasis. (PMID 12957820 ) The secretory epithelial cells of the prostate gland of humans and other animals posses a unique citrate-related metabolic pathway regulated by testosterone and prolactin. This specialized hormone-regulated metabolic activity is responsible for the major prostate function of the production and secretion of extraordinarily high levels of citrate. The key regulatory enzymes directly associated with citrate production in the prostate cells are mitochondrial aspartate aminotransferase, ...
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Citric acid cycle (tricarboxylic acid cycle, TCA cycle, Krebs cycle) is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). [Citric acid cycle. Wikipedia] |br|This biochemical diagram example shows metabolic pathways map of citric acid cycle reactions. |br|This sample was redesigned from the Wikimedia Commons file: TCA cycle.svg. [commons.wikimedia.org/wiki/File:TCA_cycle.svg] |br|This image is licensed under the Creative Commons Attribution 3.0 Unported license. [creativecommons.org/licenses/by/3.0/deed.en] |br|The metabolic pathway map example Citric acid cycle (TCA cycle) was created using the ConceptDraw PRO diagramming and vector drawing software extended with the Biology solution from the Science and Education area of ConceptDraw Solution Park. Citric Acid Cycle
Magnesium Citrate is the best of the non-food forms of magnesium. As a citrate, it is readily absorbed into the bloodstream via the citric acid cycle. Cytoplan Magnesium Citrate comes in easy-to-take gluten free capsules which are suitable for vegetarians and vegans. Cytoplan Magnesium Citrate supplement yields 80mg of elemental Magnesium in each easy-to-swallow capsule The Magnesium Citrate capsules are gluten free Magnesium is an essential mineral - nearly 70% of the bodys supply is located in the bones - magnesium contributes to the maintenance of normal bones and teeth Magnesium is involved in many metabolic processes including contributing to normal energy-yielding metabolism (from glucose) and contributing to normal nerve function Magnesium is easily depleted from our diet by food processing, cooking and food refining techniquesMagnesium contributes to: a reduction of tiredness and fatigue normal psychological functions electrolyte balance the maintenance of normal bone/teeth normal energy
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Looking for dibasic magnesium citrate? Find out information about dibasic magnesium citrate. MgHC6H5O7·5H2O A white or yellowish powder soluble in water; used as a dietary supplement or in medicine Explanation of dibasic magnesium citrate
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Citric acid is not to be confused with vitamin C It is a weak organic acid found in various fruits and vegetables Citric acid is also found in the metabolism in every form of life and is part of the citric acid cycle It can be used as a preservative flavoring in drinks and as an organic cleaning solvent The type of citric acid you purchase will depend on the intended use of the product Request A Quotation! ...
Introduction. Aim: The aim on my investigation is to find the percentage of citric acid present in lemon squash by using a method of neutralisation, by a method of titration and volumetric analysis. I will be using sodium hydroxide as an alkali, which will be neutralising the citric acid. Background Knowledge: Titration Titration is a technique for investigating the volume of solutions that react together. One solution is placed in a burette and slowly added to a fixed volume of another solution, usually measured with a pipette, until the end point of the reaction is shown using an indicator. Salts can be made by this method by repeating the titration between an acid and alkali using previously measured quantities without using the indicator. Citric acid Citric acid is the acid present in citrus fruits such as oranges and lemons. It is commonly used to add a tang to fruit drinks and lemonades. Mixed with sodium hydrogencarbonate (commonly knows as bicarbonate of soda) and sugar, it becomes ...
Abstract: CuO-ZnO-ZrO2 (CZZ) catalysts for methanol synthesis from CO2 hydrogenation were prepared by a citric acid combustion method. The combustion reactions were analyzed in terms of propellant chemistry and the combustion behavior was recorded by thermo-gravimetric/differential thermal analysis (TG-DTA). The as-prepared CZZ powders were investigated with X-ray diffraction (XRD), N2 adsorption, temperature-programmed reduction (TPR), and reactive N2O adsorption techniques and the catalytic activities were evaluated for methanol synthesis from CO2 hydrogenation. The results show that the influence of citric acid quantity on the physicochemical and catalytic properties of CZZ is subtle, and the reason is related to the characteristics of the combustion reaction. Furthermore, the relationship between the quantity of fuel (citric acid, urea, and glycine) and the properties of the catalysts was determined. The citric acid combustion method exhibits better controllability and it is a simple, fast, ...
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Several catabolic pathways converge on the citric acid cycle. Most of these reactions add intermediates to the citric acid cycle, and are therefore known as anaplerotic reactions, from the Greek meaning to fill up. These increase the amount of acetyl CoA that the cycle is able to carry, increasing the mitochondrions capability to carry out respiration if this is otherwise a limiting factor. Processes that remove intermediates from the cycle are termed cataplerotic reactions. In this section and in the next, the citric acid cycle intermediates are indicated in italics to distinguish them from other substrates and end-products. Pyruvate molecules produced by glycolysis are actively transported across the inner mitochondrial membrane, and into the matrix. Here they can be oxidized and combined with coenzyme A to form CO2, acetyl-CoA, and NADH, as in the normal cycle.[35]. However, it is also possible for pyruvate to be carboxylated by pyruvate carboxylase to form oxaloacetate. This latter ...
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Civstallization is an established method used in the initial recovery of organic acids and amino acids, and more widely used for final purification of a diverse range of compounds.. [n citric acid production, the filtered broth is treated with Ca(OH)2 so that the relatively insoluble calcium citrate crystals will be precipitated from solution. Checks are made to ensure that the Ca(OH)2 has a low magnesium content, since magnesium citrate is more soluble and would remain in solution. The calcium citrate is filtered off and treated with sulphuric acid to precipitate the calcium as the insoluble sulphate and release the citric acid. After clarification with active carbon, the aqueous citric acid is evaporated to the point of crystallization (Lockwood and Irwin, 1964; Sodeck et al., 1981; Atkinson and Mavituna, 1991). Crystallization is also used in the recovery of amino acids; Samejima (1972) has reviewed methods for glutamic acid, lysine and other amino acids. The recovery of cephalosporin C as ...
Normal prostate tissue contains high levels of citrate. In the presence of prostate cancer, the citrate level is diminished. In this paper we show that it is possible to use europium-oxytetracycline complex as a citrate fluorescent probe and consequently as a prostate cancer probe. We analyzed normal nude male mice urine and urine from nude male mice in which prostate cancer was induced by intraprostatic inoculation of DU145 cells. The urine samples were collected from the animals at the 7th, 14th, 21st, and 35th days after the surgery procedures. The intensity of europium emission at 615 nm in europium-oxytetracycline complex in the presence of citrate increases linearly. The citrate concentrations were determined from a calculated calibration curve. A concentration decrease in malignant prostate urine from the normal (PBS group) urine value from ∼8.0 mM to ∼2.4 mM (tumor group at 35th day) was found. The obtained results indicated that europium-oxytetracycline provides a significant ...
Mono- and Stereopictres of 5.0 Angstrom coordination sphere of Sodium atom in PDB 1x9j: Structure of Butyrate Kinase 2 Reveals Both Open- and Citrate-Induced Closed Conformations: Implications For Substrate-Induced Fit Conformational Changes
Description: What is Magnesium Citrate? Magnesium is a mineral that can be found in a number of foods and is most prevalent in green leafy vegetables such as spinach, nuts and grains. Benefits of Magnesium Citrate Magnesium contributes to a reduction of tiredness and fatigue and to electrolyte balance. Magnesium contributes to normal energy-yielding metabolism and normal functioning of the nervous system. Magnesium contributes to normal psychological function, muscle function and normal protein synthesis. It also contributes to the maintenance of normal bones and teeth and also has a role in the process of cell division. Who is Magnesium Citrate suitable for? For anyone engaged in a long term physical training plan, getting the right dietary balance is absolutely essential. The body requires the right kind of nutrients in order to perform and develop correctly, and whether these come from food or from supplements, they are needed for many purposes. As a dietary supplement we recommend consuming ...
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Citric acid is a weak organic acid. It is a natural preservative conservative and is also used to add an acidic or sour, taste to foods and soft drinks. In biochemistry, the conjugate base of citric acid, citrate, is important as an intermediate in the citric acid cycle and therefore occurs in the metabolism of virtually all living things.. It is colorless or white crystalline powder and mainly used as an acidulant, flavoring and preservative preservative in foods and beverages. It is also used as an antioxidant, plasticizer and detergent, builder.. Mainly used in the food, beverage trade as the sour flavor agent, flavoring agent, antiseptic as well as an antistaling agent. ...
This page contains information on the chemical Citric acid, trisodium salt, compd. with potassium citrate and citric acid, (2:2:1) including: 5 synonyms/identifiers.
Then, the subject will undergo a sodium citrate nasal douche at a specific concentration or will douche with sterile water. There will be three concentrations used (3%, 6% and 9%) and a control solution (sterile water). Patients will be randomly allocated to one of the four groups using a coded bottle system. Both patient and tester will be blinded to the solution used as these will be made in the pharmacy and coded for anonymity - the code will be broken at the end of the trial. Subjects will then be retested with the bottles and threshold levels will be observed for the four odours at 15 minute intervals over 2 hours. The purpose of the repeated tests is to determine the length of the effect (if present) of the citrate on the olfactory ability of the patients (NB: sodium citrate is a licensed product for use in body cavities (e.g. stomach, bladder) and can be found in the British National Formulary - the concentrations proposed do not exceed those used elsewhere). ...
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Professional guide for Sodium Citrate/Citric Acid. Includes: pharmacology, pharmacokinetics, contraindications, interactions, adverse reactions and more.
Save 39% Kal - Calcium Citrate D-3 1000 90 Tablets Calcium Citrate D-3 1000 3 Daily 1000 mg / 1000 IU Superior Absorption KAL Calcium Citrate D-3 1000 is a high potency formula, designed for superior absorption. Calcium is intended to provide nutritive support for healthy bones and teeth. Vitamin D has been added to enhance absorption and utilization of Calcium by the body.
"Citric Acid". The closely related acids isocitric acid, aconitic acid, and propane-1,2,3-tricarboxylic acid (tricarballylic ... Citric acid can be used as an alternative to nitric acid in passivation of stainless steel. Citric acid can be used as a lower- ... Citric acid is an alpha hydroxy acid and is an active ingredient in chemical skin peels. Citric acid is commonly used as a ... Citric acid/potassium-sodium citrate can be used as a blood acid regulator. The citric acid is included to improve palatability ...
... aka Krebs or citric acid cycle) (Q27436670). An animation of the citric acid cycle at Smith College Citric acid cycle variants ... These latter amino acids are therefore termed "ketogenic" amino acids, whereas those that enter the citric acid cycle as ... However, because of the role of the citric acid cycle in anabolism, they might not be lost, since many citric acid cycle ... To turn them into amino acids the alpha keto-acids formed from the citric acid cycle intermediates have to acquire their amino ...
"Citric acid". pubchem.ncbi.nlm.nih.gov. Retrieved 2022-08-24. "Citric Acid and Kidney Stones" (PDF). UW Health. Schwille, P. O ... It is different than citric acid which is citrate bonded by hydrogen ions (or protons) making it acidic. Citric acid does not ... This reduces uric acid supersaturation and prevents uric acid stones and cystine stones. Berg, C.; Larsson, L.; Tiselius, H. G ... but much of the citrate is citric acid; without a cation like sodium, potassium or magnesium these beverages will have less ...
Fatty acid synthesis Cholesterol synthesis The citric acid cycle which in turn leads to: Amino acid synthesis Nucleotide ... beta-oxidation of fatty acids, and during the citric acid cycle). The NADH thus produced is primarily used to ultimately ... In the citric acid cycle all the intermediates (e.g. citrate, iso-citrate, alpha-ketoglutarate, succinate, fumarate, malate and ... Furthermore, citric acid intermediates are constantly used to form a variety of substances such as the purines, pyrimidines and ...
Of the enzymes, the major functions include oxidation of pyruvate and fatty acids, and the citric acid cycle. The DNA molecules ... Increased fatty acid delivery to the heart increases fatty acid uptake by cardiomyocytes, resulting in increased fatty acid ... The citric acid cycle oxidizes the acetyl-CoA to carbon dioxide, and, in the process, produces reduced cofactors (three ... Stryer L (1995). "Citric acid cycle.". In: Biochemistry (Fourth ed.). New York: W.H. Freeman and Company. pp. 509-527, 569-579 ...
"Citric Acid Trip". Snopes.com. 2015-02-06. Retrieved 2010-07-27. "LSD given to police officer". Snopes.com. 2008-07-07. ... "the brown acid", which was allegedly bad. One possible reason people believe that they had "bad acid" could be because they ... A "bad trip" is easily caused by an expectation or fear of ill effects, which may later be blamed on "bad acid". This legend ... No brown acid: Woodstock anniversary concert draws a cell phone crowd, Associated Press Archive - August 15, 1998 United States ...
... leading to the citric acid cycle and allowing for the production of amino acids. GlcN-6-P and fructose-6-phosphate act as ... Stryer L, Tymoczko JL, Berg JM (2002). "The Citric Acid Cycle". Biochemistry. 5th Edition. White RJ, Pasternak CA (October 1967 ... Asp-273 then acts as an acid to protonate the amine leaving group. One proposed mechanism using the BsNagA and its two iron co- ... The mechanism proceeds via a strictly conserved active-site aspartic acid residue (Asp-273) that acts initially as a base to ...
Krebs cycle - also known as the TCA cycle or Citric acid cycle - is a biochemical pathway that facilitates the break down of ... "6.2: Citric Acid Cycle & Related Pathways". Biology LibreTexts. 2017-01-21. Retrieved 2022-03-28. Voet, Donald (2013). ... The shuttle also helps the production of fatty acid and lactic acid. In liver cancer cells, the TCA cycle is blocked, causing ... a fungi used in the commercial production of citric acid. All cells need the energy to survive. Mitochondria is a double- ...
It is a calcium acid salt of citric acid. Calcium citrate Monocalcium citrate Food Additives in Europe 2000, pp. 322-324, ... "Citric acid, calcium salt". pubchem.ncbi.nlm.nih.gov. Retrieved 2022-10-24. v t e (Articles without EBI source, Articles ... Acid salts, All stub articles, Organic compound stubs). ...
The citric acid cycle, also known as the Krebs cycle or the TCA (tricarboxylic acid) cycle is an 8-step process that takes the ... "Citric Acid Cycle" (PDF). Takusagawa's Note. Archived from the original (PDF) on 24 March 2012. Retrieved 4 April 2013. " ...
"The Citric Acid Cycle". Biochemistry. 5th Edition. Jordan, Frank; Furey, William; Nemeria, Natalia S.; Patel, Mulchand S. (2014 ... Energy-generating ions and molecules, such as amino acids and carbohydrates, enter the Krebs cycle as acetyl coenzyme A and ...
Voet DJ, Voet JG, Pratt CW (2010). "Chapter 17, Citric Acid Cycle". Principles of Biochemistry (4th ed.). Wiley. p. 550. ISBN ... The PDHB gene encodes a precursor protein that has 359 amino acid residues and a final mature protein that has 329 amino acids ... In forming the entire PDH complex, the 289th beta residue, aspartic acid, interacts with the 276th residue of the E2 complex, a ... Pyruvate dehydrogenase deficiency is characterized by the buildup of a chemical called lactic acid in the body and a variety of ...
Various strains of A. niger are used in the industrial preparation of citric acid (E330) and gluconic acid (E574); therefore, ... The production of citric acid (CA) is achieved by growing strains of A. niger in a nutrient rich medium that includes high ... Sackett D (2014). Citric Acid: Occurrence, Biochemistry, Applications and Processing. Nova Science Publishers Inc. p. 119. ISBN ... Max B, Salgado JM, Rodríguez N, Cortés S, Converti A, Domínguez JM (October 2010). "Biotechnological production of citric acid ...
Natural plant extracts (including natural caffeine and kola nut extract). citric, tartaric and lactic acids. Stabilizer: gum ...
Voet DJ, Voet JG, Pratt CW (2010). "Chapter 17, Citric Acid Cycle". Principles of Biochemistry (4th ed.). Wiley. p. 550. ISBN ... Pyruvate dehydrogenase deficiency is characterized by the buildup of a chemical called lactic acid in the body and a variety of ... The most common feature is a potentially life-threatening buildup of lactic acid (lactic acidosis), which can cause nausea, ...
Citric Acid-Ammonium Citrate Solutions". Journal of the American Chemical Society. 72 (6): 2354-2361. doi:10.1021/ja01162a004. ...
Although lemons contain citric acid, most citric acid is produced by fermentation using microbes that can convert sugars into ... The juice from the lemon is acidic and contains citric acid that helps lower the pH, which additionally restricts microbes that ... citric acid, which is the most important organic acid produced in tonnage and is extensively used in food and pharmaceutical ... "Microbial production of citric acid". Brazilian Archives of Biology and Technology. 42 (3): 263-276. doi:10.1590/S1516- ...
Voet DJ, Voet JG, Pratt CW (2010). "Chapter 17, Citric Acid Cycle". Principles of Biochemistry (4th ed.). Wiley. p. 550. ISBN ... The PDHA1 subunit has been shown to be regulated by free fatty acids during bouts of exercise. The presence of free fatty acids ... The preliminary peptide encoded by this gene was 29 amino acids at the very start of the sequence that correspond to a typical ... Pyruvate dehydrogenase deficiency is characterized by the buildup of a chemical called lactic acid in the body and a variety of ...
November 22 - Hans Krebs (b. 1900), German medical doctor and biochemist; discoverer of the citric acid cycle. December 6 - ...
Although it is often referred to as a citric acid salt of caffeine, as implied by its name, caffeine citrate in fact consists ... The drug is prepared by combining anhydrous caffeine with citric acid monohydrate and sodium citrate dihydrate. Caffeine ... Smit, Jared P.; Hagen, Eric J. (2015-03-01). "Polymorphism in Caffeine Citric Acid Cocrystals". Journal of Chemical ... Smit, Jared P.; Hagen, Eric J. (2015-03-01). "Polymorphism in Caffeine Citric Acid Cocrystals". Journal of Chemical ...
In another method, isoniazid was claimed to have been made from citric acid starting material. It can in theory be made from ... Baizer, Manuel M.; Dub, Michael; Gister, Sidney; Steinberg, Nathan G. (1956). "Synthesis of Isoniazid from Citric Acid". ... Isonicotinic acid hydrazide is also used in chromatography to differentiate between various degrees of conjugation in organic ... This process inhibits the synthesis of mycolic acids, which are required components of the mycobacterial cell wall. A range of ...
Citric acid content is around 1%. It has no seeds. The time of ripening is mid to late March. The flavor is similar to that of ...
Citric acid-used for corrosion prevention. Isopropanol-used to winterize the chemicals to ensure it doesn't freeze. The most ... Acids-hydrochloric acid or acetic acid is used in the pre-fracturing stage for cleaning the perforations and initiating fissure ... Stimulation of wells with acid, instead of explosive fluids, was introduced in the 1930s. Due to acid etching, fractures would ... "Acid fracturing". Society of Petroleum Engineers. Retrieved 12 October 2014. Khan, Salmaan A. "Government Roads, Subsidies, and ...
"Citric acid detected in sister's body". Dong-A Ilbo. September 2, 1988. Retrieved July 16, 2019. "'Blood' because of debt... 86 ... The police had carried out autopsies on four people who died under suspicious circumstances, finding citric acid in three of ...
... can be prepared creating a solution of citric acid and toluenesulfonic acid, which forms a 1,3-diester. That ... Citrazinic acid is commonly formed in citric acid based carbon nanodots (CND). It is responsible for the blue light found in ... Baizer MM, Dub M, Gister S, Steinberg NG (July 1956). "Synthesis of isoniazid from citric acid". Journal of the American ... citric acid CNDs. The wavelengths of light emitted by citrazinic in CNDs can be shifted by changing the pH of the solution. ...
"Citric Acid and Kidney Stones" (PDF). uwhealth.org. Archived (PDF) from the original on 5 July 2010. Heaney RP (March 2006). " ... However, citric acid does not alkalinize urine like alkali citrate, which is citrate bonded with sodium, potassium and ... This is because when citrate is metabolized (mostly by liver and some by kidney), the protons in citric acid will neutralize ... Reducing the pH to 5.0 decreases the solubility of uric acid to less than 8 mg/100 ml. The formation of uric-acid stones ...
Müller, Ulrich F.; Tor, Yitzhak (2014). "Citric Acid and the RNA World". Angewandte Chemie International Edition. 53 (21): 5245 ... providing further evidence for central role of citric acid in primordial metabolism. doi:10.1126/science.1241888 "UMn CBS". ... non enzymatic RNA replication in primitive protocells is only possibly in presence of weak cation chelator like citric acid, ...
This enzyme participates in citric acid cycle. Lill U, Schreil A, Eggerer H (1982). "Isolation of enzymically active fragments ... This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The ...
"Citric Acid Content of Concentrated Milk Products". The Journal of Biological Chemistry: 457. Retrieved 2008-12-05. " ... a sample of milk with calcium chloride to reduce its acidity and then with alkaline hypochlorite to preserve the fatty acids in ...
Malfunction of the citric acid cycle due to PDH deficiency deprives the body of energy and leads to an abnormal buildup of ... and through hydrogen bonding to amino acids. While over 20 amino acids can be found in the active site, amino acids Tyr 89, Arg ... The conversion is crucial because acetyl-CoA may then be used in the citric acid cycle to carry out cellular respiration. To ... Ochoa S (1954). "Enzymic mechanisms in the citric acid cycle". Advances in Enzymology and Related Areas of Molecular Biology. ...
Common food acids include vinegar, citric acid, tartaric acid, malic acid, folic acid, fumaric acid, and lactic acid. Acidity ... Citranaxanthin - color Citric acid - food acid Citric acid esters of mono- and diglycerides of fatty acids - emulsifier Citrus ... Phosphated distarch phosphate - thickener, vegetable gum Phosphoric acid - food acid Phytic acid - preservative Pigment Rubine ... Acetic acid - acidity regulator Acetic acid esters of mono- and diglycerides of fatty acids - emulsifier Acetone Acetylated ...
... cleaning the dentures citric acid - removes stains sodium perborate sodium polyphosphate potassium monopersulfate - cleaning ...
... citric acid) lemon flavor and artificial coal tar color. The book takes particular aim at the pharmaceutical market in the ...
... glycolysis and fed into the citric acid cycle. Although some more ATP is generated in the citric acid cycle, the most important ... Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle ( ... For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all ... All amino acids are synthesized from intermediates in glycolysis, the citric acid cycle, or the pentose phosphate pathway. ...
A fruit salt or fruit salts is an effervescent compound made up of organic acids such as citric acid or tartaric acid and salts ... citric acid) or grapes (tartaric acid) - forms further salts such monosodium citrate in solution with the carbonates or ... and citric acid. Its main market is in India. Campbell, W. A. (June, 1966) James Crossley Eno and the Rise of the Health Salts ... with flavorings like lemon into an effervescent compound with citric or tartaric acid proved especially popular and set off a ...
... tricarboxylic/Krebs/citric acid) cycle. This indicates that Sulfolobus has a TCA cycle system similar to that found in ... The tetraethers help Sulfolobus species survive extreme acid as well as high temperature. S. solfataricus has been found in ... Nucleic Acids Research. 47 (9): 4442-4448. doi:10.1093/nar/gkz246. PMC 6511854. PMID 31081040. "GTDB release 05-RS95". Genome ...
The fluid consists of nutrients including fructose and citric acid, prostaglandins, and fibrinogen. Nutrients help support ...
Ingredients: 1 oz (28 g) caffeine citrate 3 oz (85 g) citric acid 1 US fl oz (30 ml) vanilla extract 1 US qt (946 ml) lime ... Fluid extract of Coca: 3 drams USP Citric acid: 3 oz Caffeine: 1 oz Sugar: 30 lbs Water: 2.5 gal Lime juice: 2 pints (1 quart) ... citric acid and lime juice in 1 quart boiling water add vanilla and flavoring when cool." Flavoring (Merchandise 7X): 1 qrt ... or a substitute such as a water solution of citric acid and sodium citrate at lime-juice strength. Mix together 1⁄4 drachm ( ...
... with flavorings like lemon into an effervescent compound with citric or tartaric acid proved especially popular and set off a ... such as amino acids and antibiotics. Those requiring a large dose. Those that are susceptible to light, oxygen, or moisture. It ...
... by the reaction of the amino acid glycine with succinyl-CoA from the citric acid cycle. In plants, algae, bacteria (except for ... These high reactive oxygen species react with susceptible cellular organic biomolecules such as; lipids, aromatic amino acids, ... and nucleic acid heterocyclic bases, to produce oxidative radicals that damage the cell, possibly inducing apoptosis or even ... the committed step for porphyrin biosynthesis is the formation of δ-aminolevulinic acid (δ-ALA, 5-ALA or dALA) ...
There are five usual fruit acids: citric acid, glycolic acid, lactic acid, malic acid and tartaric acid. Many other alpha ... Alpha hydroxy acids (AHAs) are naturally occurring carboxylic acids such as glycolic acid, a natural constituent of sugar cane ... Salicylic acid is a beta hydroxy acid. It is antibacterial (mostly bacteriostatic, except in high concentrations when it is ... It is becoming common for beta hydroxy acid (BHA) peels to be used instead of the stronger alpha hydroxy acid (AHA) peels due ...
... which often include citric acid and other fruit acids, predicted to have an impact on human teeth. Carbon dioxide gas dissolved ... but much less acidic than the acid in the stomach. A normal, healthy human body maintains pH equilibrium via acid-base ... "AERIAL ACID: a short history of artificial mineral waters" (PDF). idus.us.es. Retrieved May 8, 2017. "XI. Experiments on ... Carbonic acid, britannica.com Funston, Lindsay (April 27, 2018). "What Is Seltzer - Is Seltzer Bad For You". Delish. Retrieved ...
The isoforms IDH1 and IDH2 catalyze the same reaction outside the context of the citric acid cycle and use NADP+ as a cofactor ... The IDH step of the citric acid cycle is often (but not always) an irreversible reaction due to its large negative change in ... In humans, IDH exists in three isoforms: IDH3 catalyzes the third step of the citric acid cycle while converting NAD+ to NADH ... Within the citric acid cycle, isocitrate, produced from the isomerization of citrate, undergoes both oxidation and ...
Organic acids and their salts are used widely in food products, e.g. lactic acid, citric acid, acetic acid, either as ... Phenol also known as carbolic acid was one of the first chemicals which was used as an antimicrobial agent. It has high ... For example, beef carcasses often are sprayed with acids, and then rinsed or steamed, to reduce the prevalence of Escherichia ... Phenolic compounds can also deactivate enzymes and damage the amino acids in microbial cells. Phenolics such as fentichlore, an ...
Mullin, J. W.; Leci, C. L. (1969). "Evidence of molecular cluster formation in supersaturated solutions of citric acid". ...
It was obtained in very low yield upon heating citric acid, a source of a six-carbon linear chain, with P4S10. More efficient ...
... is used in the production of wine and citric acid. In the EU, ferrocyanides (E 535-538) were, as of 2017 ... After having tried so vainly to decompose Prussian blue by acids, I made recourse to alkalies. I put a half ounce of this [ ... Treatment of potassium ferrocyanide with nitric acid gives H2[Fe(NO)(CN)5]. After neutralization of this intermediate with ...
... diluted vinegar or citric acid (to flush out residual iron gall compounds), water, diluted ammonia (if needed to flush out ... 11.7 g tannic acid 3.8 g gallic acid C 6H 2(OH) 3COOH 15 g iron(II) sulfate 3 cm3 hydrochloric acid (used to prevent sediment ... Modern formulations also tend to use hydrochloric acid whereas many historical inks used sulfuric acid. Hydrochloric acid is a ... 4.0 g tannic acid 1.5 g gallic acid 5.5 g ferrous sulfate crystals FeSO 4·7H 2O 5.0 g concentrated hydrochloric acid 5.0 g dye ...
A source of citric acid and lemon juice is added to help preserve the cordial and add tartness. The mixture is then covered and ...
Aerobic means "with oxygen", and refers to the use of oxygen in the body's energy-generating process (the citric acid cycle). ...
... malonic acid, and citric acid in dilute sulfuric acid, the ratio of concentration of the cerium(IV) and cerium(III) ions ... One of the most common variations on this reaction uses malonic acid (CH2(CO2H)2) as the acid and potassium bromate (KBrO3) as ... This is due to the cerium(IV) ions being reduced by malonic acid to cerium(III) ions, which are then oxidized back to cerium(IV ... The only common element in these oscillators is the inclusion of bromine and an acid. The reactions are important to ...
... polylactic acid (polylactide), polyhydroxyurethanes, epoxidized soybean oil with citric acid and polybutadiene. Vitrimers were ...
He is credited with first isolating vitamin C and discovering the components and reactions of the citric acid cycle. He was ... His research involved isolating an organic acid, which he then called "hexuronic acid", from adrenal gland tissue. He accepted ... Citric acid cycle, Honorary Fellows of the Royal Society of Edinburgh, Hungarian biochemists, Hungarian emigrants to the United ... There Szent-Györgyi and his research fellow Joseph Svirbely found that "hexuronic acid" was actually the thus far unidentified ...
... citric acid - citric acid cycle - cladistics - cloning - coenzyme - cofactor (biochemistry) - colchicine - collagen - colloid ... amino acid - amino acid receptor - amino acid sequence - amino acid sequence homology - aminobutyric acid - ammonia - AMPA ... nucleic acid - nucleic acid regulatory sequence - nucleic acid repetitive sequence - nucleic acid sequence homology - nucleon ... lactic acid - lactic acid autotroph - lactic fermentation - lagging strand - laminin - LDL receptor - Le Chatelier's principle ...
Synthesis and Characterization of Citric Acid based Polyester Hydroxyapetite Nanocomposites ", Global Journal for Research ... Synthesis of N,N'-bis(2,6-diisopropylphenyl)- 1,7-di(2,2'-bithiophenyl)perylene-3,4:9,10-tetracarboxylic acid diimide (bt-pdi- ... "Synthesis of 1,7-disubstituted N,N'-bis(hexyl) perylene-3,4:9,10-tetracarboxylic acid diimide (PDI) small molecule for organic ... 10-tetracarboxylic acid diimide (BT-PDI-IA) Small Molecular Dye for Organic Solar Cell Application" Third International ...
Biochemical cycles (i.e., the urea cycle or the citric acid cycle) and their metabolites can be represented by means of hands ...
... from the amino acid glycine and succinyl-CoA from the citric acid cycle (Krebs cycle). The rate-limiting enzyme responsible for ... Heme D is another derivative of heme B, but in which the propionic acid side chain at the carbon of position 6, which is also ... In addition, a unique sulfonamide ion linkage between the sulfur of a methionyl amino-acid residue and the heme 2-vinyl group ... For example, the ability of hemoglobin to effectively deliver oxygen to tissues is due to specific amino acid residues located ...
... and adding salt or citric acid. Virgin coconut oil (VCO) can be produced from fresh coconut milk, meat, or residue. Producing ... In the following content, the expressions "fatty acids" and "acid" below refer to esters rather than carboxylic acids. The ... while other significant saturated fats are myristic acid (16.7 g), palmitic acid (8.6 g), and caprylic acid (6.8 g). ... Lauric acid, a 12-carbon chain fatty acid, is often removed because of its high value for industrial and medical purposes. The ...
Lambeth DO (2002). "What is the function of GTP produced in the Krebs citric acid cycle?". IUBMB Life. 54 (3): 143-4. doi: ... Occurs in glycolysis and in the citric acid cycle. Unlike oxidative phosphorylation, oxidation and phosphorylation are not ...
Acetyl-CoA is arguably of an even higher level of importance, acting as one of the integral components of the Citric Acid/Kreb ... resembling the Citric Acid/Kreb cycle enzyme complex 2-oxoglutarate dehydrogenase. Two types of familial hyperlysinemia have ... Hoffmann GF, Kolker S (2012). "Cerebral organic acid disorders and other disorders of lysine catabolism". In Saudubray JM, van ... Jones EE, Broquist HP (June 1965). "Saccharopine, an intermediate of the aminoadipic acid pathway of lysine biosynthesis. Ii. ...
Citric acid urine test measures the level of citric acid in urine. ... citric acid test; Renal tubular acidosis - citric acid test; Kidney stones - citric acid test; Urolithiasis - citric acid test ... Citric acid urine test measures the level of citric acid in urine. ... A low level of citric acid may mean renal tubular acidosis and a tendency to form calcium kidney stones. ...
... the SparkNotes The Citric Acid Cycle Study Guide has everything you need to ace quizzes, tests, and essays. ...
Citric Acid / sodium citrate. Known as: CITRIC ACID/SODIUM CITRATE, sodium citrate citric acid, acid citrate citric sodium ... Citric Acid 66.8 MG/ML / sodium citrate 100 MG/ML Oral Solution ...
... or ascorbic acid, are both found in many of the same fruits and vegetables. However, their health effects and commercial uses ... Unlike vitamin C, citric acid is not one of the recommended vitamins and minerals you need each day. Citric acid also has not ... Citric acid is most concentrated in lemons and limes; their juice contains 1.44 and 1.38 grams of citric acid per ounce, ... Citric acid can also improve the activity of other antioxidants. Citric acid may get a bad reputation, because it has been ...
We also Provide Trading Suppliers & Manufacture for 77-92-9 Citric acid. ... Anhydrous citric acid and 1 portions of nitric acid and 2 copies of the action of sulphuric acid form nitric acid ester C3H5 ( ... 1) reaction with acid Citric acid and fuming sulfuric acid mixed, at room temperature, which produce aconitic acid, slightly ... 2) Reaction with alkali The citric acid is fused with K2CO3 or KOH or nitric acid to obtain oxalic acid and acetic acid or ...
... at 3.5% CAGR during 2021-2028 , Size, Share, Analysis & ... Citric Acid Market Share, Growth, Outlook to 2025 Citric acid is a weak organic acid predominantly used in food, beverages, ... Citric Acid Market. The Citric Acid Market was valued around USD 3,070 million in 2020 and is expected to grow at a CAGR of 3.5 ... Future of Fermented Citric Acid Market Size 2026 The recent research report on the global Fermented Citric Acid Industry market ...
Evaluation is based on knowledge of the metabolic fate and lack of toxicity of the constituent citric acid and fatty acid ... citric, lactic and tartaric acids, provided that the total food additive intake of tartaric acid does not exceed 30 mg/kg. See ... CITRIC AND FATTY ACID ESTERS OF GLYCEROL Explanation These emulsifiers have been evaluated for acceptable daily intake by the ... produced nearly the same yield of citric acid in the same two-hour period as spontaneous hydrolysis at pH 7.5 to 8.5 (Lang, ...
NASDAQ: EVFM) today announced that the U.S. Food and Drug Administration (FDA) has approved Phexxi™ (lactic acid,... ... ABOUT PHEXXI™ (lactic acid, citric acid and potassium bitartrate) VAGINAL GEL. Phexxi is indicated for the prevention of ... NASDAQ: EVFM) today announced that the U.S. Food and Drug Administration (FDA) has approved Phexxi™ (lactic acid, citric acid ... U.S. FDA Approves Evofem Biosciences Phexxi™ (lactic acid, citric acid and potassium bitartrate), the First and Only Non- ...
Can anyone tell me what amount of food grade citric acid to use per quart of water to descale my espresso machine? (It has a 2 ... What ratio citric acid / water to descale?. Beginner and pro baristas share tips and tricks for making espresso. ... Can anyone tell me what amount of food grade citric acid to use per quart of water to descale my espresso machine? (It has a 2 ... What if it is "activated" citric acid? My machine is about 5 months old, we are in a hard water area. I have purchased Everpure ...
How to take Tricitrates (Citric Acid K Citrate Na Citrate)?. Use Tricitrates (Citric Acid K Citrate Na Citrate) exactly as ... Tricitrates (Citric Acid K Citrate Na Citrate). Generic Name:Citric acid, potassium citrate, and sodium citrate ... What drugs and food should I avoid while taking Tricitrates (Citric Acid K Citrate Na Citrate)?. Ask your doctor before using ... What should I do if I missed a dose of Tricitrates (Citric Acid K Citrate Na Citrate)?. Take the medicine as soon as you can, ...
Find 1 ways to say CITRIC ACID CYCLE, along with antonyms, related words, and example sentences at Thesaurus.com, the worlds ... Acetone is derived from decomposition of diacetic acid, and this in turn from beta-oxybutyric acid by oxidation. ... Uric acid is decreased before an attack of gout and increased afterward, but its etiologic relation is still uncertain. ... Diacetic acid occurs in the same conditions as acetone, but is less frequent and has more serious significance. ...
CITRIC ACID. OH. O ║. O ║. OH - C - CH 2 - C - CH 2 - C - OH . O ║ HO - C . 2 - hydroxy - 1,2,3 - propanetricarboxylic acid . ... Citric Acid - . tamim alkuwari. what is citric acid?. citric acid is a sharp acid found in most of the sour fruits like ... CITRIC ACID - . abdul rahman al khulaifi 7c. what is citric acid?. citric acid is naturally found in citrus food it can ... Citric Acid uses - Citric acid could be a weak organic acid having the formula c6h8o7. acid is found naturally in citrus ...
It is the primary acid found in fruits such as lemon, lime, grapefruit, orange, pineapple and others. Citric acid is also used ... One teaspoon of citric will raise the titratable acid in a gallon of wine by .15 per cent tartaric. ...
Citric acid Citric acid is simply the molecule that makes lemon juice acidic. It is also present in many of the human bodys ... Citric acid. Citric acid is simply the molecule that makes lemon juice acidic. It is also present in many of the human bodys ... To adjust a cosmetic products pH (around 5.5 if it is to be applied to the skin), there are two major compounds, citric acid, ...
Share and Growth Outlook The Anhydrous and Liquid Citric Acid market is expected to register fluctuating growth trends in the ... Anhydrous and Liquid Citric Acid Market Insights - Market Size, ... Anhydrous and Liquid Citric Acid trade and price analysis help ... Anhydrous and Liquid Citric Acid Market Insights - Market Size, Share and Growth Outlook The Anhydrous and Liquid Citric Acid ... Anhydrous and Liquid Citric Acid Market Research Scope Global Anhydrous and Liquid Citric Acid market size and growth ...
Asia Pacific Citric Acid Market expected to grow at a CAGR of 6.4% by 2026.The countries of Asia-Pacific covered in this report ... Asia Pacific Citric Acid Market Growth and Forecast (2022 - 2027):. Asia Pacific Citric Acid Market has been estimated at USD ... Asia Pacific Citric Acid Market Segmentation Analysis:. The Asia-Pacific market for Citric Acid is segmented on the basis of ... Citric acid market is driven by factors like wide applicability of citric acid as an acidulant, emulsifier, preservative, ...
Citric Acid is inherently natural as it occurs in citric fruits, produced by fermentation of carbohydrates Acidulant (useful to ... Citric Acid is inherently natural as it occurs in citric fruits, produced by fermentation of carbohydrates Acidulant (useful to ... adjust pH of products to make them more acid / less alkaline). Chelating effect (neutralizes minerals to enhance activity of ...
Citric Acid Market Report, Trends, By Form (Liquid & Powder), By Application (Food & Beverage, Pharmaceutical), and By Region ... Citric Acid Market, Citric Acid Market Dynamics, Citric Acid Market Growth, Citric Acid Market Key players, Citric Acid Market ... Introduction of the Citric Acid Market Report. The citric acid refers to organic acid that occurs naturally in citrus fruits. ... Global Citric Acid Market by Region. * *North America Citric Acid Market (Option 1: As a part of the free 25% customization) * ...
The store is under construction and no orders are accepted at this moment ...
Inconceivably brief laser pulses and the signature acid of citrus fruits have helped Nebraska engineers improve the thermal ... So the team tried cleaning the laser-pelted copper with one of two acids, acetic or citric, finding that the citric better ... Laser-pelted, citric acid-washed copper could boost heat transfer. Pocket Science: Exploring the What, So what and Now ... By eating away at those subsurface oxide layers, too, the citric acid left voids that reduced the materials thermal ...
... exporter of citric acid monohydrate from Vadodara,Gujarat,India.Our citric acid monohydrate are known for its quality and are ...
Commonly used for flavoring, citric acid is also used in cosmetics as... ... Citric acid is a bitter acid found naturally in many fruits. ... Are corn citric acid and fruit citric acid the same thing as ... Peanut butter does not have citric acid in it. It does have another acid in it that is in the same family as citric acid. These ... A few years ago I cut citric acid from my diet totally. Not just citric fruit but everything that had citric acid as an ...
Bulk Citric Acid * Please note we will do our best to match product supplied to the weight requested, but actual product ... Bulk Citric Acid. * Please note we will do our best to match product supplied to the weight requested, but actual product ... Be the first to review "Bulk Citric Acid, 100g" Cancel reply. Your email address will not be published. Required fields are ...
Citric Acid Powder, Phosphoric Acid, Acetic Acid, Etc. We are located in Indore, Madhya Pradesh, India. ...
Do citric acid cleaners work? Click to learn more! ... Citric Acid Cleaners. Citric acid is one alternative frequently ... citric acid acts as a water softener, chelating agent, pH adjuster and preservative. Citric acid is safe, plant-derived and ... What is citric acid? According to acidpedia.org, it is "a naturally-occurring acid which is found in large quantities in fruits ... Does Citric Acid Cleaner Work?. We live in a world where finding out what people think about a product is easier than ever. If ...
... and Citric AcidNo Procedural Spawn Locations found for Beaker With Hydrogen Peroxide and Hexamethylentetramin and Citric Acid ... 1) Add Citric Acid to Beaker with Hydrogen Peroxide and Hexamethylentetramin → Creates → 1 x Beaker With Hydrogen Peroxide and ... Recipes / Crafts that Use Beaker With Hydrogen Peroxide and Hexamethylentetramin and Citric Acid as an Ingredient / How to Use ... Recipes / Crafts to Create Beaker With Hydrogen Peroxide and Hexamethylentetramin and Citric Acid / How to make Beaker With ...
Price Trends of Citric Acid in its Latest Insights and Dashboard*Product Description:*Regions Covered to Evaluate Citric Acid ... Industrial Uses Impacting Citric Acid Price Trend:. Citric acid is used in the production of detergents, electroplating, and ... Also Check Citric Acid Production Cost Report - https://www.procurementresource.com/production-cost-report-store/citric-acid ... Also Check Citric Acid Industry Report - https://www.procurementresource.com/reports/citric-acid-industry-report ...
Drink large amounts of orange juice because it contains citric acid and vitamin c which both help metabolize ... Citric acid, Fumaric acid, Oxalic acid, Maleic acid, Acetic acid, Formic acid. Column: Heritage MA. Separation Modes: reversed- ... Citric acid, Fumaric acid, Oxalic acid, Maleic acid, Acetic acid, Formic acid. Column: Heritage MA. Separation Modes: reversed- ... Citric acid is more acidic than ascorbic acid. Therefore, citric acid is recommended when canning tomatoes to lower the pH or ...
keywords = "Acetic acid, Citric acid, Organic acids, Salmonella typhimurium, Sesame paste, Tahini", ... S. Typhimurium cells were not detected in the presence of 0.5% acetic acid after 7d or with 0.5% citric acid after 21d at the ... S. Typhimurium cells were not detected in the presence of 0.5% acetic acid after 7d or with 0.5% citric acid after 21d at the ... S. Typhimurium cells were not detected in the presence of 0.5% acetic acid after 7d or with 0.5% citric acid after 21d at the ...
Citric acid. Citric acid, most prevalent in citrus fruits such as oranges and lemons, may help reduce acne lesions in some ... As such, it may be best for a person should apply citric acid products at night and wear sunscreen during the day. ... While there is little research on whether citric acid can clear up acne, people can try applying lemon juice directly to ... Bae, J. Y., & Park, S. N. (2016). Evaluation of antimicrobial activities of ZnO, citric acid and a mixture of both against ...

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