Trichosanthes
Cicatrix, Hypertrophic
Keloid
A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
Gingival Overgrowth
Neoplasm Regression, Spontaneous
Acne Keloid
A type of acneiform disorder in which secondary pyogenic infection in and around pilosebaceous structures ends in keloidal scarring. It manifests as persistent folliculitis of the back of the neck associated with occlusion of the follicular orifices. It is most often encountered in black or Asian men.
Protective Clothing
Pressure
Therapeutic Equivalency
Internet
Linguistics
Natural Language Processing
Dermabrasion
Rejuvenation
Chemexfoliation
Melanosis
Trichloroacetic Acid
Cosmetic Techniques
Lasers, Dye
Tunable liquid lasers with organic compounds (i.e., dye) which have a strong absorption band, used as the active medium. During emission, the dye has to be optically excited by another light source (e.g., another laser or flash lamp). The range of the emission wavelength may be anywhere from the ultraviolet to the near infrared (i.e., from 180 to 1100nm). These lasers are operated in continuous wave and pulsed modes. (UMDNS, 2005)
Lasers, Solid-State
Lasers which use a solid, as opposed to a liquid or gas, as the lasing medium. Common materials used are crystals, such as YAG (YTTRIUM aluminum garnet); alexandrite; and CORUNDUM, doped with a rare earth element such as a NEODYMIUM; ERBIUM; or HOLMIUM. The output is sometimes additionally modified by addition of non-linear optical materials such as potassium titanyl phosphate crystal, which for example is used with neodymium YAG lasers to convert the output light to the visible range.
Port-Wine Stain
A vascular malformation of developmental origin characterized pathologically by ectasia of superficial dermal capillaries, and clinically by persistent macular erythema. In the past, port wine stains have frequently been termed capillary hemangiomas, which they are not; unfortunately this confusing practice persists: HEMANGIOMA, CAPILLARY is neoplastic, a port-wine stain is non-neoplastic. Port-wine stains vary in color from fairly pale pink to deep red or purple and in size from a few millimeters to many centimeters in diameter. The face is the most frequently affected site and they are most often unilateral. (From Rook et al., Textbook of Dermatology, 5th ed, p483)
Lasers
An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.
Trigger Finger Disorder
A painful disability in the hand affecting the finger or thumb. It is caused by mechanical impingement of the digital flexor tendons as they pass through a narrowed retinacular pulley at the level of the metacarpal head. Thickening of the sheath and fibrocartilaginous metaplasia can occur, and nodules can form. (From Green's Operative Hand Surgery, 5th ed, p2137-58).
Diaper Rash
Burns
Sulfadiazine
Dystonic Disorders
Acquired and inherited conditions that feature DYSTONIA as a primary manifestation of disease. These disorders are generally divided into generalized dystonias (e.g., dystonia musculorum deformans) and focal dystonias (e.g., writer's cramp). They are also classified by patterns of inheritance and by age of onset.
Writing
Editorial Policies
Publishing
Voice
Copyright
It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)
Bibliometrics
Education, Graduate
Artificial Intelligence
Publications
Dermatopontin expression is decreased in hypertrophic scar and systemic sclerosis skin fibroblasts and is regulated by transforming growth factor-beta1, interleukin-4, and matrix collagen. (1/85)
Dermatopontin is a recently discovered extracellular matrix protein with proteoglycan and cell-binding properties and is assumed to play important roles in cell-matrix interactions and matrix assembly. In this study we examined the expression of dermatopontin mRNA and protein in skin fibroblast cultures from patients with hypertrophic scar and patients with systemic sclerosis. Dermatopontin mRNA and protein levels were reduced in fibroblast cultures from hypertrophic scar lesional skin compared with fibroblasts from normal skin of the same hypertrophic scar patient. Fibroblast cultures from systemic sclerosis patient involved skin also showed significantly reduced expression of dermatopontin compared with normal skin fibroblasts from healthy individuals. We also investigated the effects of cytokines and matrix collagen on dermatopontin expression in normal cultured fibroblasts. Transforming growth factor-beta1 increased dermatopontin mRNA and protein levels, while interleukin-4 reduced dermatopontin expression. Substrate coated with type I collagen reduced dermatopontin mRNA levels, the reduction being more prominent in three-dimensional collagen matrices. Our results suggest that the decreased expression of dermatopontin is associated with the pathogenesis of fibrosis in hypertrophic scar and systemic sclerosis, and that the effect of the cytokines and matrix collagen on dermatopontin may have important implications for skin fibrosis. (+info)Expression and role of IL-15 in post-burn hypertrophic scars. (2/85)
Hypertrophic scarring is a skin disorder that occurs after wounding and thermal injury. There is accumulating evidence that immunologic processes such as infiltration of activated T lymphocytes and altered cytokine production may play a role in the formation of hypertrophic scars. Interleukin-15, a cytokine identified as a T cell growth factor, also acts as a chemoattractant for T cells and has pro-inflammatory properties. We investigated the expression and the role of this cytokine in hypertrophic scarring. IL-15 expression was compared in skin biopsies of hypertrophic scars (HS) both in active (AHS) and in remission (RHS) phases, in normotrophic scars (NTS) and in normal skin using reverse transcriptase-polymerase chain reaction and immunohistochemistry. IL-15 expression in HS was significantly higher than in NTS or normal skin. Furthermore, AHS expressed higher levels of IL-15 than RHS. Immunohistologic analysis of AHS samples showed strong IL-15 immunoreactivity in keratinocytes and Langerhans cells in the epidermis and in macrophages, fibroblasts, and dermal dendritic cells in the dermis. High levels of IL-15 expression in AHS correlated with abundant infiltration of activated CD3+ cells. Ex vivo experiments indicate that IL-15 can sustain the proliferative response of T cells derived from AHS but not from RHS and NTS. In addition, IL-15 prevents both cytokine deprivation and activation-induced apoptosis of T cells derived from AHS. Taken together, these results suggest that IL-15 can be involved in the recruitment, proliferation, and apoptosis inhibition of T cells in AHS. The findings that the evolution from an AHS to a RHS is associated with a decrease in IL15 expression, and with a loss of IL-15 responsiveness in ex vivo-cultured T cells, indicate that this cytokine plays an important role in the biology of pathologic scar formation. (+info)Mechanical forces induce scar remodeling. Study in non-pressure-treated versus pressure-treated hypertrophic scars. (3/85)
Reparative process of second and third degree burns usually results in hypertrophic scar formation that can be treated by pressure. Although this method is efficient, its mechanisms of action are not known. In this work, we have studied the histological organization of hypertrophic scars submitted to pressure. Skin biopsies were performed 2 to 7 months after the onset of treatment in two adjacent regions of the scar, non-pressure- or pressure-treated and analyzed by immunohistochemistry and transmission electron microscopy for extracellular matrix organization and cellular morphology. In non-pressure-treated regions, fibrillin deposits did not present the classical candelabra-like pattern under epidermis and were reduced in dermis; in pressure-treated regions the amount was increased compared to non-pressure-treated regions but the organization was still disturbed. In non-pressure-treated regions, elastin was present in patch deposits; in pressure-treated regions elastin formed fibers, smaller than in normal dermis. Tenascin was present in the whole dermis in non-pressure-treated regions, whereas in pressure-treated regions it was observed only under epidermis and around vessels, as in normal skin. alpha-Smooth muscle actin-expressing myofibroblasts were absent in normal skin, present in large amounts in non-pressure-treated regions, and almost absent in pressure-treated regions. The disturbed ultrastructural organization of dermal-epidermal junction observed in non-pressure-treated regions disappeared after pressure therapy; typical features of apoptosis in fibroblastic cells and morphological aspects of collagen degradation were observed in pressure-treated regions. Our results show that, in hypertrophic scars, pressure therapy restores in part the extracellular matrix organization observed in normal scar and induces the disappearance of alpha-smooth muscle actin-expressing myofibroblasts, probably by apoptosis. We suggest that the pressure acts by accelerating the remission phase of the postburn reparative process. (+info)Severe obstructive sleep apnoea secondary to pressure garments used in the treatment of hypertrophic burn scars. (4/85)
Obstructive sleep apnoea (OSA) secondary to pressure garments used to treat hypertrophic scarring of burns has never been reported. The present study describes two children who presented with OSA following introduction of such garments for management of hypertrophic scars following severe facial and upper body burns. Complex sleep polysomnography confirmed severe OSA with desaturations sufficient to result in physiological dysfunction that significantly improved on removal of the garments. As there is little evidence to suggest that the use of such garments alters the end result, the potentially serious side effect of obstructive sleep apnoea should be considered before their use is advised. (+info)Expression of oncoproteins c-fos and c-jun in hypertrophic scars and chronic dermal ulcers and their regulation of basic fibroblast growth factor. (5/85)
OBJECTIVE: To explore the characteristics of oncoprotein expression of c-fos and c-jun in hypertrophic scars and chronic dermal ulcers and their regulation of basic fibroblast growth factor (bFGF). METHODS: Tissues of hypertrophic scars (n = 8), chronic dermal ulcers (n = 8) and normal skin (n = 5) were taken from 21 patients with burns and chronic dermal ulcers in operation. The ABC immunohistochemical method was used to characterize the gene product expression of c-fos, c-jun and bFGF in the above tissues. RESULTS: In normal skin, both c-fos and c-jun protein expression and bFGF protein expression were observed. The signals of both oncoproteins were localized mainly in subcutaneous fibroblasts, but, positive expression of the bFGF protein was mainly in keratinocytes. In hypertrophic scars, positive expression of both oncoproteins could be found mainly in fibroblasts, but bFGF was mainly in fibroblasts and endothelial cells. In chronic dermal ulcers, endothelial cells, some of inflammatory cells and fibroblasts were positive for both of oncoproteins, but the expression of bFGF was only seen in fibroblasts and endothelial cells. CONCLUSIONS: The results indicate that the interaction between both oncoproteins and bFGF exists, and the regulating action between protooncogenes and bFGF is a major course in wound healing. The different expressions of c-fos and c-jun gene products play an important role in regulate bFGF action, thus affecting wound healing. (+info)Alterations in fibroblast alpha1beta1 integrin collagen receptor expression in keloids and hypertrophic scars. (6/85)
Keloids and hypertrophic scars are significant symptomatic clinical problems characterized by excess collagen. Although extensive research has focused on fibroblasts and collagen turnover in these aberrant scars, little work has been done on the expression of integrins (cell membrane structures that link cells to extracellular matrix) within these lesions. Integrin-mediated regulation of collagen synthesis has previously been observed in explanted fibroblasts from normal and fibrotic dermis, and integrin alpha1 knockout mice maintain increased collagen synthesis consistent with a role for alpha1beta1 in providing negative feedback on collagen synthesis. These findings suggested the need to evaluate integrin roles in keloids and hypertrophic scars. In this study we examined integrin expression in keloids (n = 11), hypertrophic scars (n = 5), radiation ulcers (n = 2), and normal skin specimens (n = 8). We used a novel approach to analysis by isolating dermal fibroblasts directly from tissue (without explant culture) and determining surface integrin expression by flow cytometry. We found that keloids and hypertrophic scars have marked alterations in fibroblast integrin expression and contain several distinct populations of fibroblasts. One of these populations expresses high levels of alpha1 integrin, and the proportion of these cells is higher in keloids (63% +/- 3.6% SEM) and hypertrophic scars (45% +/- 2.7% SEM) than in normal skin tissues (28% +/- 4.7% SEM). The different populations of fibroblasts defined by integrin expression merge, however, when the cells are serially cultured, suggesting that there may be aspects of the dermal microenvironment that maintain the integrin phenotypic heterogeneity in dermal fibroblasts. (+info)Expression of epidermal growth factor receptor and related phosphorylation proteins in hypertrophic scars and normal skin. (7/85)
OBJECTIVE: To study the potential signal pathway involved in pathogenesis of hypertrophic scar formation. METHODS: The samples of scar were obtained from patients with burn wound scars 6 - 28 months post-burn, while the samples of normal control skin came from the donor site of the same patients. Immunohistochemistry and light microscopy techniques were used to identify the expression of epidermal growth factor receptor (EGFR) and phosphotyrosine proteins (p-Tyr), as well as the phosphorylation of signal transducer and activator of transcription 3 (Stat3) in both hypertrophic scars (n = 6) and normal skin (n = 6). RESULTS: Significant differences were observed in the p-Tyr and EGFR positive expression keratinocytes both in hypertrophic scars and normal skin. The expression of p-Tyr, EGFR and Stat3 protein was greater in hypertrophic scars than in normal skin. However, there was no significant difference in p-Stat3 expression between scar tissues and normal skin. CONCLUSION: Different tyrosine kinase activity occurs in hypertrophic scars and normal cutaneous tissues. Initially, varied expression of EGFR is due to different ligand stimulations. However, phosphotyrosine protein and Stat3 are subsequently activated through phosphorylation. In scar tissues, although EGFR has an intrinsic tyrosine kinase activity when activated by EGFR correlated ligand, phosphorylation of Stat3 showed no significant changes. Therefore, cellular signal pathways are induced by EGFR, which might play a role in hypertrophic scar pathogenesis. (+info)Prevention and treatment of excessive dermal scarring. (8/85)
Today, wound management to avoid excessive scar formation is increasingly important, especially in populations with Fitzpatrick 3 or higher skin pigmentation. Medical science and industrial development are devoting more effort toward understanding and offering better therapy to control scars. However, advances in scar management have been hampered by the confusing or ambiguous terminology. There is no consensus on what amount of post-traumatic skin scar formation is "normal" and what should be considered "hypertrophic". In the World Health Organization's ICD-9, there is no diagnostic code for hypertrophic scar--only keloid is listed. Yet, the medical and scientific literature distinguishes them as different conditions. Our experience suggests that the diagnosis of keloid disease is greatly over-rendered. For black patients, an elevated scar seems, by default, diagnosed as keloid by most. This confusion results in inappropriate management of scar formation, and occasionally contributes to decision making related to elective or cosmetic surgery. Given that patients are expecting better outcomes from wound care today than in the past, this review article attempts to capture the essential biological factors related to wound scar production and discusses treatment options and indications used by the authors. (+info)
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The Microvasculature In Cutaneous Wound Healing In The Female Red Duroc Pig Is Similar To That In Human Hypertrophic Scar And...
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Treatment of hypertrophic scars using a long-pulsed dye laser with cryogen-spray cooling.
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Hypertrophic Cicatrix
- Hypertrophic Scar
Summary Report | CureHunter
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Lasers deemed highly effective treatment for excessive scars
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Time might heal all wounds, but not all scars - Bluffton Sun
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Had gallbladder removed. Raised, itchy and hot bumps appeared on the scars. How to treat this?
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hypertrophic scar | Tabers Medical Dictionary
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Dermatology
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List of MeSH codes (C17)
... cicatrix, hypertrophic MeSH C17.800.120.425 - keloid MeSH C17.800.120.425.125 - acne keloid MeSH C17.800.174.100 - ...
List of skin conditions
... hypertrophic lupus erythematosus) Winchester syndrome Abnormalities of dermal fibrous and elastic tissue are caused by problems ... chronic cicatrix keratosis) Clonal seborrheic keratosis Common seborrheic keratosis (basal cell papilloma, solid seborrheic ... idiopathic hypertrophic osteoathorpathy, Touraine-Solente-Gole syndrome) Peeling skin syndrome (acral peeling skin syndrome, ... Hypertrophic scar Immunosuppression-associated Kaposi sarcoma Infantile digital fibromatosis (inclusion body fibromatosis, ...
WikiGenes - Cicatrix, Hypertrophic
Gene context of Cicatrix, Hypertrophic. *Expression and role of IL-15 in post-burn hypertrophic scars [24]. ... Biological context of Cicatrix, Hypertrophic. *Gene expression profiles from hypertrophic scar fibroblasts before and after IL- ... High impact information on Cicatrix, Hypertrophic. *Letter: Polyglycolic-acid sutures and hypertrophic scars [6]. ... Disease relevance of Cicatrix, Hypertrophic. *Surprisingly, the level of the crosslinking enzyme lysyl oxidase is normal or ...
CICATRIX in the Treatment of Hypertrophic Scars and Keloids Scars - No Study Results Posted - ClinicalTrials.gov
Hypertrophic Cicatrix
- Hypertrophic Scar
Summary Report | CureHunter
Hypertrophic Cicatrix: An elevated scar, resembling a KELOID, but which does not spread into surrounding tissues. It is formed ... Hypertrophic Scar; Hypertrophic Scars; Cicatrix, Hypertrophic; Cicatrices, Hypertrophic; Hypertrophic Cicatrices; Scar, ... Hypertrophic Cicatrix (Hypertrophic Scar). Subscribe to New Research on Hypertrophic Cicatrix An elevated scar, resembling a ... Drugs and Important Biological Agents (IBA) related to Hypertrophic Cicatrix: 1. SiliconesIBA 07/01/2009 - "This pilot study ...
Occipitocervical fusion for reduction of traumatic periodontoid hypertrophic cicatrix in: Journal of Neurosurgery Volume 73...
Right: Axial MR image (TE 20 msec, TR 1000 msec) of the C-2 area showing resolution of the periodontoid hypertrophic cicatrix ... Right: Axial MR image (TE 20 msec, TR 1000 msec) of the C-2 area showing resolution of the periodontoid hypertrophic cicatrix ... Periodontoid hypertrophic cicatrix resulting from trauma, as demonstrated by magnetic resonance (MR) imaging, is essentially ... Left: Sagittal T1-weighted magnetic resonance (MR) image showing traumatic periodontoid hypertrophic cicatrix with intermediate ...
Cicatrix, Hypertrophic | CTD
Effectiveness of Pressure Garment Therapy After Burns - Full Text View - ClinicalTrials.gov
Cicatrix, Hypertrophic. Wounds and Injuries. Pathological Conditions, Anatomical. Cicatrix. Fibrosis. Pathologic Processes. ... Patients over 65 years will be excluded since the incidence of hypertrophic scarring in persons over 65 is too low to warrant ... Since burn depth is extremely variable from patient to patient and since hypertrophic scarring is greatly influenced by age and ... The most devastating outcomes following burns is the ugly, itchy, hypertrophic scar that interferes with work and all other ...
A Substantial Equivalence Study of RD04723 and Predicate Device - Full Text View - ClinicalTrials.gov
Cicatrix, Hypertrophic. Cicatrix. Fibrosis. Pathologic Processes. Pathological Conditions, Anatomical. Collagen Diseases. ... Hypertrophic Scar Keloid Scar Device: RD047-023 Device: Predicate Device Not Applicable ... Have a hypertrophic or keloid scar accessible for treatment and evaluation. *Negative pregnancy test for women of childbearing ... Kelo-cote® Scar Gel for the Management of Hypertrophic or Keloid Scars. ...
Overexpression of manganese superoxide dismutase in human dermal fibroblasts enhances the contraction of free floating collagen...
Rejuvenation of the skin surface: chemical peel and dermabrasion
3 Ways to Prevent Keloid and Hypertrophic Scars - wikiHow
How to Prevent Keloid and Hypertrophic Scars. Nothing can leave you feeling more self-conscious than a nasty scar. While some ... Español: prevenir las cicatrices queloides e hipertróficas, Русский: предотвратить келоидные и гипертрофические рубцы, Italiano ... Know who is at risk for hypertrophic scar formation. Hypertrophic scars are less visible and stay within the boundaries of the ... Two of the most common forms of scar tissue are keloid and hypertrophic. They normally form over a cut or wound to the skin. In ...
Treatment of hypertrophic scars using a long-pulsed dye laser with cryogen-spray cooling.
Hypertrophic scars are common and cause functional and psychologic morbidity. The conventional pulsed dye laser (585 nm) has ... Cicatrix, Hypertrophic / ethnology, pathology, therapy*. Combined Modality Therapy. Cryotherapy* / adverse effects. Erythema / ... with cryogen-spray cooling device in the treatment of hypertrophic scars. Fifteen Asian patients with 22 hypertrophic scars ... Hypertrophic scars are common and cause functional and psychologic morbidity. The conventional pulsed dye laser (585 nm) has ...
Syndrome of occipitoatlantoaxial hypermobility, cranial settling, and Chiari malformation Type I in patients with hereditary...
Hal K Hawkins's Research on Smoke
| CureHunter
Ärrsvulst | Svensk MeSH
Congenital Varicella Syndrome - NORD (National Organization for Rare Disorders)
Certain areas of the skin may consist of thickened, overgrown (hypertrophic) scar tissue (cicatrix), and surrounding skin may ... cicatrix scarring occurs on one or more of the arms and/or legs. Affected arms and/or legs and/or fingers or toes may also be ... hypertrophic). Such scarring may appear in a characteristic "zigzag" pattern, and the surrounding skin may be abnormally ... appear abnormally hardened (indurate), red, and inflamed (erythema). Such cicatrix scarring typically occurs on one or more of ...
Keloid and hypertrophic scar | DermNet NZ
Hypertrophic scar, Cheloid, Keloid cicatrix. Authoritative facts from DermNet New Zealand. ... What is the treatment of a hypertrophic or keloid scar?. A hypertrophic scar generally settles in time or with treatment, but a ... This is known as a hypertrophic scar. A hypertrophic scar is limited to the damaged skin. ... Keloid and hypertrophic scar. Author: A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand, 1997. Updated September 2014. ...
Keloid
Ensaios Clínicos Controlados para tratamentos de Cicatrizes Hipertróficas e Queloides | RefNet
"Cicatrix, Hypertrophic/SU" OR "Cicatrix, Hypertrophic/TH" OR "Cicatrix, Hypertrophic/DT" OR ("Hypertrophic Cicatrices" OR " ... "Hypertrophic Cicatrices" OR "Hypertrophic Cicatrix" OR "Hypertrophic Scar" OR "Hypertrophic Scars" OR Keloid OR keloids OR ... "Cicatrix, Hypertrophic/SU" OR MH:"Cicatrix, Hypertrophic/TH" OR MH:"Cicatrix, Hypertrophic/DT")) Estratégia de busca (Pubmed). ... "Hypertrophic Cicatrix" OR "Hypertrophic Scar" OR "Hypertrophic Scars" OR Keloid OR keloids OR "Hypertrophic keloid" OR " ...
Practical Management of Common Skin Injuries, Lacerations, Wounds, Trigger Fingers, and Burns | American Board of Family...
The main scar types include "flat" cicatrix, widespread, atrophic, hypertrophic, keloid, and contracture scars.58 ... Hypertrophic scars, unlike previous ones, are raised. The scar will be red and painful with hypertrophy limited to the site of ... Hypertrophic scars and scars with ambiguous diagnoses should be first treated with pressure therapy such as silicone gel ... Hypertrophic scars are classically seen after burn injuries and tend to show some spontaneous regression over time. ...
Six Questions For . . .: Six Questions for Lynsey Morandin, Publisher/Editor, Hypertrophic Literary
Cicatrix Publishing (1) * Circa: a Literary Review (1) * CircleShow (1) * Clever Magazine (1) ... SQF: If Hypertrophic Literary had a theme song, what would it be and why?. LM: After we hit the final button on every issue of ... Lynsey Morandin: We started Hypertrophic because we wanted to give a voice and a platform to the little guy. Ive worked in ... Hypertrophic Literary publishes prose, poetry and artwork "that make us feel something: joy, nausea, shock, desperation - ...
Early Carbon Dioxide Laser Therapy for Alleviation of Incisional Scar Burden - Full Text View - ClinicalTrials.gov
Cicatrix in children - Things You Didn't Know
Kam on cicatrix in children: Clearly keloids have greater tendency to occur in darker skinned races and to that degree they do ... Some people get hypertrophic scars called keloids and may benefit from steroid injection. ...Read more ... Cicatrix (Definition) Cicatrix = wound scar due to formation & contraction of fibrous tissue. ...Read more ... Cicatrix: Cicatrix = wound scar due to formation & contraction of fibrous tissue. ...Read more ...
Clinical Safety and Scar Prevention Study of a Topical Antifibrotic Compound FS2.
Scar | Keloid Scar | MedlinePlus
Find Research Outputs
- Johns Hopkins University
Suburban Hospital - Research Output
- Johns Hopkins University
Wang, X.<...
Scars and keloids3
- It can also remove hypertrophic scars and keloids. (breathingtherightway.com)
- In Plastic Surgery the cryotherapy is an efficient method in the treatment of hypertrophic scars and keloids. (elsevier.com)
- Clinicians always find it difficult to treat hypertrophic scars and keloids. (semanticscholar.org)
Developed hypertrophic scars2
- 28 (16.2%) of these developed hypertrophic scars, but the model was otherwise safe. (elsevier.com)
- All injury sites developed hypertrophic scars. (elsevier.com)
Cardiomyopathy5
- Cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE) revealed a substantial variation in the extent of myocardial scarring, a pathological hallmark of hypertrophic cardiomyopathy (HCM). (cdc.gov)
- Hypertrophic cardiomyopathy. (cdc.gov)
- Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias. (cdc.gov)
- Patient populations that are more likely to need epicardial VT ablation include patients with non-ischemic cardiomyopathy (NICM) who have a predisposition for epicardial scarring such as arrhythmogenic right ventricular cardiomyopathy (ARVC), Chagas disease, hypertrophic cardiomyopathy (HCM), sarcoidosis, Brugada syndrome and occasionally epicardial premature ventricular contractions (PVC) and patients with ischemic cardiomyopathy with significant mid-myocardial scarring. (acc.org)
- We sought to determine the relation between myocardial extracellular volume (ECV), left ventricular (LV) diastolic function, and exercise tolerance in patients with hypertrophic cardiomyopathy (HCM). (houstonmethodist.org)
Treat hypertrophic scars1
- abstract = "Pressure garments have been used prophylactically and to treat hypertrophic scars, resulting from serious burns, since the early 1970s. (hw.ac.uk)
Fibrosis1
- Extracorporeal shock waves (ESWs), acoustic waves, are effective in the treatment of hypertrophic scars, due to their ability to modulate fibrosis. (bvsalud.org)
Keloids and hypertrophic6
- Keloids and hypertrophic scars are frequent observed. (bvsalud.org)
- The main difference between keloids and hypertrophic scars is the scar extension in relation to the original incision, where former extends beyond the original incision while the latter respects it. (bvsalud.org)
- Background Tranilast is an anti-allergic agent known to inhibit the release of histamine, interleukin-1β, transforming growth factor β1, and platelet-derived growth factor from various cells and currently is used to treat allergic diseases, keloids, and hypertrophic scars. (fujita-hu.ac.jp)
- Management of keloids and hypertrophic scars. (semanticscholar.org)
- Keloids and hypertrophic scars represent an exuberant healing response that poses a challenge for physicians. (semanticscholar.org)
- Bleomycin in the treatment of keloids and hypertrophic scars by multiple needle punctures. (semanticscholar.org)
Burns6
- Purpose - To determine the effectiveness of custom-fit pressure garment therapy in the prevention of hypertrophic scarring in healed burns. (clinicaltrials.gov)
- The most devastating outcomes following burns is the ugly, itchy, hypertrophic scar that interferes with work and all other aspects of life. (clinicaltrials.gov)
- Goals and Objectives - The investigators plan to determine the effectiveness of pressure garment therapy in the control of hypertrophic scarring in healed burns. (clinicaltrials.gov)
- Scar helps reduce hypertrophic scars, recent and old scars, burns and acne marks, stretch marks and keloids. (bcnpharma.com)
- In a swine hypertrophic burn scar model, normal skin and 3 × 3-cm partial thickness thermal burns underwent dermatome resection at 1 week post burn and randomized to four subcutaneous injections of saline or TE (either 0.5, 5, or 10 mg/ml) spaced 3 days apart. (elsevier.com)
- This review explores the potential use of photobiomodulation (PBM), already used for the treatment of other skin conditions, such as acne, hypertrophic scars, wrinkles, and burns, as potential novel therapy for HS. (elsevier.com)
Periodontoid cicatrix3
- A case of traumatic periodontoid cicatrix is presented in which posterior fusion resulted in reduction of the anterior mass lesion, clearly demonstrated by MR imaging. (thejns.org)
- Partial decompression of the periodontoid cicatrix and resultant partial widening of the spinal cord are shown. (thejns.org)
- Sagittal MR image (TE 20 msec, TR 500 msec) showing resolution of the periodontoid cicatrix, with expansion and normal configuration of the spinal cord. (thejns.org)
Scarring10
- The etiology of periodontoid hypertrophic scarring, both traumatic and rheumatoid, is discussed in light of MR findings, and treatment implications are considered. (thejns.org)
- Pressure garment therapy is routinely used to minimize hypertrophic scarring even though there is no scientifically valid data that this therapy is efficacious. (clinicaltrials.gov)
- Since burn depth is extremely variable from patient to patient and since hypertrophic scarring is greatly influenced by age and race/origin, the between subjects design requires very large numbers of subjects. (clinicaltrials.gov)
- While men and women are equally susceptible to hypertrophic scarring, there are specific groups that are more prone to it. (wikihow.com)
- Such cicatrix scarring typically occurs on one or more of the arms and/or legs, which may also be malformed, underdeveloped (hypoplastic), and abnormally shortened (reduction deformities). (rarediseases.org)
- In most cases, cicatrix scarring occurs on one or more of the arms and/or legs. (rarediseases.org)
- Unpredictable hypertrophic scarring (HS) occurs after approximately 35% of all surgical procedures and causes significant physical and psychological complaints. (bvsalud.org)
- Hypertrophic scarring caused by sternotomy is prevalent among Asians. (nih.gov)
- There is a whole range of different ways in which people scar, the poorest types of scarring are Hypertrophic and Keloid Scarring. (nycdermatologist.com)
- Keloid and hypertrophic scarring represent chronic disfiguring dermatoses with a high resistance to therapy. (semanticscholar.org)
Keloid scar2
- What is the treatment of a hypertrophic or keloid scar? (dermnetnz.org)
- These may be similar at first but whereas a hypertrophic scar will not go outside of the boundaries of the wound a Keloid scar would, patients can have a single keloid or a number of them. (nycdermatologist.com)
Tissues1
- It is differentiated from a hypertrophic scar ( CICATRIX, HYPERTROPHIC ) in that the former does not spread to surrounding tissues. (ki.se)
Prevention4
- A randomized, placebo-controlled, double-blind, prospective clinical trial of silicone gel in prevention of hypertrophic scar development in median. (nih.gov)
- A randomized, placebo-controlled, double-blind, prospective clinical trial of silicone gel in prevention of hypertrophic scar development in median sternotomy wound. (nih.gov)
- The effect of silicone gel in prevention of hypertrophic scar development in sternotomy wounds is promising. (nih.gov)
- To evaluate the effectiveness of corticosteroid ointment in hypertrophic scars prevention following Cesarean section. (org.pk)
Treatment8
- The purpose of this study is to determine whether a developmental formulation is substantially equivalent to the predicate device in the treatment of hypertrophic and keloid scars. (clinicaltrials.gov)
- Treatment of hypertrophic scars using a long-pulsed dye laser with cryogen-spray cooling. (biomedsearch.com)
- This prospective study was performed to determine the effectiveness of the long-pulsed dye laser (595 nm) with cryogen-spray cooling device in the treatment of hypertrophic scars. (biomedsearch.com)
- The long-pulsed dye laser (595-nm) equipped with cryogen spray cooling device is an effective treatment of hypertrophic scars and can improve scar pliability and texture and decrease scar erythema and associated symptoms. (biomedsearch.com)
- A hypertrophic scar generally settles in time or with treatment, but a keloid may persist and prove resistant to treatment. (dermnetnz.org)
- please suggest will cicatrix and PRP treatment will work pl. (healthtap.com)
- CICATRIX is recommended for the treatment of keloid and hypertrophic scars. (e-kosmetika.lv)
- Their group previously demonstrated high-patient satisfaction for the treatment of hypertrophic burn scar (HBS) with the erbium: yttrium aluminum garnet (Er:YAG) laser, but this and other literature supporting the practice suffer from a common weakness of a reliance on subjective assessments by patients or providers. (elsevier.com)
Traitement1
- Elle commence son traitement avec CicaLux, un dispositif facile d'utilisation qui améliore les cicatrices, sur sa propre cicatrice de césarienne de 3 ans, encore rouge et hypertrophique. (cicalux.com)
Intervention1
- Le dispositif CicaLux a été conçu pour atténuer l'apparence des cicatrices qui apparaissent à la suite d'une intervention chirurgicale telle qu'une abdominoplastie, une chirurgie mammaire ou une césarienne. (cicalux.com)
Posterior1
- Z-plasty was performed at the posterior midline of the neck to prevent hypertrophic scar formation. (elsevier.com)
Traumatic1
- Sagittal T 1 -weighted magnetic resonance (MR) image showing traumatic periodontoid hypertrophic cicatrix with intermediate signal intensity. (thejns.org)
Skin9
- Certain areas of the skin may consist of thickened, overgrown (hypertrophic) scar tissue (cicatrix), and surrounding skin may appear abnormally hardened (indurate), red, and inflamed (erythema). (rarediseases.org)
- In many cases, certain areas of the skin may consist of scar tissue (cicatricial) that is thickened and overgrown (hypertrophic). (rarediseases.org)
- A hypertrophic scar is limited to the damaged skin. (dermnetnz.org)
- Methods: In July 2006 ~ August 2007 during the surgical resection,specimens of 35 cases including hypertrophic scars (10 cases),keloids (10 cases),mature scars specimens (6 cases)and normal skin specimens (9 cases)were collected. (cnki.com.cn)
- Cicatrix Cream, is a cream of topical use indicated to take care of the skin with marks of injuries and scars by postoperative, scars by caesarean section, burn marks, acne marks, scars by elimination of tattoos and piercings. (bcnpharma.com)
- The resulting attenuation coefficients in the vasculature-masked regions of the dermis of human burn-scar patients are lower in hypertrophic (3.8±0.4 mm-1) and normotrophic (4.2±0.9 mm-1) scars than in contralateral or adjacent normal skin (6.3±0.5 mm-1). (surrey.ac.uk)
- After tons and tons of studies made by dedicated people, those who are devoted to skin care and the like, this cicatrix scar cream was born. (breathingtherightway.com)
- Despite the development of new elastin fibers, skin flexibility was not improved, possibly because of insufficient elastin fiber maturation or the hypertrophic model used. (elsevier.com)
- CICATRIX is essential for skin repair after mechanical, chemical and thermal damages, cold and freezing injuries, as well as posttraumatic and postoperative damages. (e-kosmetika.lv)
Decompression1
- Axial MR image (TE 20 msec, TR 1000 msec) of the C-2 area showing resolution of the periodontoid hypertrophic cicatrix and decompression of the spinal cord, with copious perimedullary subarachnoid space. (thejns.org)
Topical1
- Cicatrix cream is a product for topical use, different from ointments, cicatrix can not be used in inflamed areas. (bcnpharma.com)
Patients1
- Fifteen Asian patients with 22 hypertrophic scars were treated by the long-pulsed dye laser (595 nm) with cryogen-spray cooling device. (biomedsearch.com)
Minimize1
- This study may popularize the use of silicone gel in all types of surgery to minimize the formation of hypertrophic scars in the early postoperative period. (nih.gov)
Acne1
- Acne keloidalis nuchae (AKN) is a condition characterized by follicular-based papules and pustules that form hypertrophic or keloid-like scars. (nycdermatologist.com)
Boundaries of the original2
- Hypertrophic scars are less visible and stay within the boundaries of the original damage. (wikihow.com)
- 1. Hypertrophic: Those growing inside the boundaries of the original wound. (piel-belgrano.com.ar)