Thoracic Duct
Chyle
Paracentesis
Pleural Effusion
Picibanil
Osteolysis, Essential
Pleurodesis
Chest Tubes
Pleural Cavity
Iodophors
Pseudochylothorax in pleural effusion due to coronary artery bypass surgery. (1/145)
This study describes a 64-yr-old male with a chronic left pleural effusion following a coronary artery bypass 3 yrs earlier. On thoracocentesis, turbid fluid was obtained with crystals of cholesterol on microscopic examination, establishing the diagnosis of pseudochylothorax. The pleural fluid cholesterol level was 207 mg x dL(-1) (5.36 mmol x L(-1)). This is the first report of pseudochylothorax in a chronic pleural effusion due to coronary artery bypass surgery. (+info)Chylothorax, chylopericardium and lymphoedema--the presenting features of signet-ring cell carcinoma. (2/145)
This report describes a patient with chylous pleural and pericardial effusions in conjunction with severe lymphoedema resembling elephantiasis. The chylous effusions and generalized lymphoedema were associated with a signet-ring cell carcinoma. (+info)Chylothorax after myocardial revascularization with the left internal thoracic artery. (3/145)
A 38-year-old male underwent coronary artery bypass grafting (CABG). A saphenous vein graft was attached to the left marginal branch. The left internal thoracic artery was anastomosed to the left anterior descending artery (LAD). The early recovery was uneventful and the patient was discharged on the 5th postoperative day. After three months, he came back to the hospital complaining of weight loss, weakness, and dyspnea on mild exertion. Chest X-rays showed left pleural effusion. On physical examination, a decreased vesicular murmur was detected. After six days, the diagnosis of chylothorax was made after a milky fluid was detected in the plural cavity and total pulmonary expansion did not occur. On the next day, both anterior and posterior pleural drainage were performed by videothoracoscopy, and prolonged parenteral nutrition (PPN) was instituted for ten days. After seven days the patient was put on a low-fat diet for 8 days. The fluid accumulation ceased, the drains were removed and the patient was discharged with normal pulmonary expansion. (+info)Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1. (4/145)
Members of the integrin family of adhesion receptors mediate both cell-cell and cell-matrix interactions and have been shown to play vital roles in embryonic development, wound healing, metastasis, and other biological processes. The integrin alpha9beta1 is a receptor for the extracellular matrix proteins osteopontin and tenacsin C and the cell surface immunoglobulin vascular cell adhesion molecule-1. This receptor is widely expressed in smooth muscle, hepatocytes, and some epithelia. To examine the in vivo function of alpha9beta1, we have generated mice lacking expression of the alpha9 subunit. Mice homozygous for a null mutation in the alpha9 subunit gene appear normal at birth but develop respiratory failure and die between 6 and 12 days of age. The respiratory failure is caused by an accumulation of large volumes of pleural fluid which is rich in triglyceride, cholesterol, and lymphocytes. alpha9(-/-) mice also develop edema and lymphocytic infiltration in the chest wall that appears to originate around lymphatics. alpha9 protein is transiently expressed in the developing thoracic duct at embryonic day 14, but expression is rapidly lost during later stages of development. Our results suggest that the alpha9 integrin is required for the normal development of the lymphatic system, including the thoracic duct, and that alpha9 deficiency could be one cause of congenital chylothorax. (+info)Paragonimiasis miyazakii associated with bilateral pseudochylothorax. (5/145)
A 37-year-old man who suffered from bilateral pleural effusions, subcutaneous abdominal induration and blood eosinophilia, was admitted to our hospital. He had ingested raw crabs at a pub-restaurant before the onset of his symptoms. His pleural effusions were chyliform containing cholesterol crystals, and a high level of immunoglobulin E (36,580 IU/ml) and anti-Paragonimus miyazakii antibody were detected. He was effectively treated with praziquantel. This case suggests that paragonimiasis should be strongly suspected if blood eosinophilia, pseudochylothorax, and a high level of immunoglobulin E in pleural effusion are detected. (+info)Pulmonary lymphangiomyomatosis (LAM) developing chylothorax. (6/145)
We describe a case of pulmonary lymphangiomyomatosis (LAM) with chylothorax that developed in a 46-year-old Japanese woman. This patient exhibited clinical symptoms of dyspnea and chest X-ray showed right pleural effusion. Thoracocentesis demonstrated chylous effusion. Chest computed tomography (CT) scan revealed multiple cystic lesions. Subsequent thoracoscopy revealed the chylorrhea from swelled vessels on the diaphragm. The clinical diagnosis, based on histological examinations with biopsy specimens obtained by thoracoscopy, was pulmonary LAM. Although the hormone therapy was not effective, chylous effusion was improved by the pleurodesis. Pulmonary LAM developing chylothorax is rare in Japan. (+info)Thoracoscopic ligation of the thoracic duct. (7/145)
OBJECTIVE: When nonoperative treatment of chylothorax fails, thoracic duct ligation is usually performed through a thoracotomy. We describe two cases of persistent chylothorax, in a child and an adult, successfully treated with thoracoscopic ligation of the thoracic duct. METHODS: A 4-year-old girl developed a right chylothorax following a Fontan procedure. Aggressive nonoperative management failed to eliminate the persistent chyle loss. A 72-year-old insulin-dependent diabetic man was involved in a motor vehicle accident, in which he sustained multiple fractured ribs, a right hemopneumothorax, a right femoral shaft fracture, and a T-11 thoracic vertebral fracture. Subsequently, he developed a right chylothorax, which did not respond to nonoperative management. Both patients were successfully treated with thoracoscopic ligation of the thoracic duct. RESULTS: The child had significant decrease of chyle drainage following surgery. Increased drainage that appeared after the introduction of full feedings five days postoperatively was controlled with the somatostatin analog octreotide. The chest tube was removed two weeks after surgery. After two years' follow-up, she has had no recurrence of chylothorax. The adult had no chyle drainage following surgery. He was maintained on a medium-chain triglyceride diet postoperatively for two weeks. The chest tube was removed four days after surgery. After six months' follow-up, he has had no recurrence of chylothorax. CONCLUSIONS: Thoracoscopic ligation of the thoracic duct provides a safe and effective treatment of chylothorax and may avoid thoracotomy and its associated morbidity. (+info)Video-assisted thoracic surgery for the management of pleural and pericardial effusion in Behcet's syndrome. (8/145)
A 28-year-old man, who presented with pleural and pericardial chylous effusion secondary to superior vena cava syndrome, was diagnosed with Behcet's syndrome. A pericardial window was created by video-assisted thoracic surgery to relieve cardiac tamponade, and this technique also enabled lung biopsy, pleural abrasion, and drainage of the pleural effusion. We report this case because of its rarity. To the best of our knowledge, the literature contains no other report of the use of video-assisted thoracic surgery for creating a pericardial window for the treatment of cardiac tamponade in a case of Behcet's syndrome. (+info)There are several potential causes of chylothorax, including:
1. Injury or trauma to the chest wall or lymphatic vessels
2. Cancer, such as lung, breast, or lymphoma
3. Infection, such as tuberculosis or cat-scratch disease
4. Genetic conditions, such as Turner syndrome or Noonan syndrome
5. Inflammatory conditions, such as rheumatoid arthritis or sarcoidosis
6. Postoperative complications
7. Pancreatitis
8. Abdominal tumors
9. Thoracic injuries
Symptoms of chylothorax may include:
1. Shortness of breath
2. Chest pain that worsens with deep breathing or coughing
3. Coughing up cloudy, milky fluid (chyle)
4. Fever
5. Night sweats
6. Weight loss
7. Fatigue
8. Swelling in the legs or arms
Diagnosis of chylothorax is typically made through a combination of physical examination, medical history, and diagnostic tests such as chest X-rays, computed tomography (CT) scans, and ultrasound. Treatment options for chylothorax depend on the underlying cause, but may include:
1. Draining the fluid from the pleural space through a procedure called thoracentesis
2. Medications to manage symptoms such as pain and fever
3. Surgery to repair any underlying damage or injuries
4. Chemotherapy or radiation therapy to treat underlying cancer
5. Infection treatment if the chylothorax is caused by an infection
6. Conservative management with supportive care, such as oxygen therapy and respiratory therapy, if the condition is not severe.
The symptoms of chylous ascites can include abdominal distension, pain, nausea, vomiting, and diarrhea. The condition is often diagnosed through a physical examination, imaging tests such as CT scans or ultrasound, and a sample of the ascitic fluid drawn from the peritoneal cavity.
Treatment options for chylous ascites depend on the underlying cause of the condition, but may include chemotherapy, radiation therapy, surgery, or drainage of the ascitic fluid. In some cases, a procedure called paracentesis may be performed to remove excess fluid and relieve symptoms.
Prognosis for patients with chylous ascites is generally poor, as it is often a sign of an underlying malignancy or other serious condition. However, the outlook can vary depending on the specific cause of the condition and the effectiveness of treatment.
Essential osteolysis is a rare genetic disorder that affects the bones and is characterized by progressive bone resorption, resulting in bone loss and deformity. It is caused by mutations in the TCIRG1 gene, which codes for a protein involved in the regulation of bone metabolism.
The symptoms of essential osteolysis typically begin in early childhood and may include bone pain, bowing or curvature of the limbs, short stature, and increased risk of fractures. The disorder can also lead to secondary effects such as joint contractures, muscle weakness, and spinal deformities.
There is no cure for essential osteolysis, and treatment is focused on managing the symptoms and preventing further bone loss. This may include physical therapy, braces or orthotics, pain management medications, and in some cases, surgery to correct deformities or stabilize weakened bones.
Essential osteolysis is a rare condition, affecting only about 1 in 100,000 individuals worldwide. It is often misdiagnosed or underdiagnosed, and the exact prevalence is not well understood. However, with advances in genetic testing and medical imaging, early diagnosis and proper management of the condition are becoming more common.
There are several causes of lymphangiectasis, including:
1. Genetic mutations
2. Infections such as filariasis or tularemia
3. Inflammatory conditions such as rheumatoid arthritis or sarcoidosis
4. Trauma to the lymph vessels
5. Tumors that block the flow of lymph fluid
6. Radiation therapy or chemotherapy
7. Infectious diseases such as HIV/AIDS
8. Vitamin deficiencies such as vitamin C or B12 deficiency
The diagnosis of lymphangiectasis is based on a combination of physical examination, medical history, and diagnostic tests such as imaging studies (e.g., CT or MRI scans), lymphoscintigraphy, and biopsy.
Treatment for lymphangiectasis depends on the underlying cause and may include:
1. Antibiotics to treat infections
2. Pain management medications
3. Anti-inflammatory drugs to reduce swelling
4. Compression garments or bandaging to reduce swelling
5. Elevation of the affected limb to reduce swelling
6. Surgery to remove blockages or repair damaged lymph vessels
7. Physical therapy to improve lymphatic drainage
8. Medications to treat underlying conditions such as rheumatoid arthritis or HIV/AIDS
Prognosis for patients with lymphangiectasis varies depending on the underlying cause and severity of the condition. In general, early diagnosis and treatment can improve outcomes and reduce the risk of complications such as infection, fibrosis, and lymphedema.
Chylothorax
Afghan Hound
Gorham's disease
Right lymphatic duct
Milroy's disease
Octreotide
Lymphangioleiomyomatosis
Double aortic arch
Lymphangiomatosis
Coarctation of the aorta
Congenital stenosis of vena cava
Thoracic duct
Bioelectricity
Fryns syndrome
FOXC2
Oren O'Neal
Hydrops fetalis
Chest tube
Pleural disease
Fontan procedure
Arvind Kumar (surgeon)
Hydrothorax
Yellow nail syndrome
Acupuncture
Lymphatic system
Pleural effusion
Chyle
Multidisciplinary Management of Chylothorax - PubMed
Kidshealth: Chylothorax | Akron Children's Hospital
Chylothorax | Radiology Reference Article | Radiopaedia.org
Successful conservative treatment of chylothorax following oesophagectomy - a clinical algorithm
Transudative chylothorax and frailty: a diagnostic and therapeutic challenge | BMJ Case Reports
WHO EMRO | Chylothorax after coronary artery bypass and internal mammary artery harvesting: a case report | Volume 16, issue 10...
IMSEAR at SEARO: Chylothorax: A rare presentation of Constrictive Pericarditis.
Lymphoscintigraphy findings in patients with chylothorax: influence of biochemical parameters. | EJNMMI Res;13(1): 72, 2023...
Chylothorax - News From Journal World
The Jill and Mark Fishman Center for Lymphatic Disorders Publications | Children's Hospital of Philadelphia
Successful Management of Postoperative Chylothorax in a Neonate after Coarctation Repair
Pleural Disorders | Pleurisy | Pleural Effusion | MedlinePlus
Parapneumonic Pleural Effusions and Empyema Thoracis: Background, Pathophysiology, Etiology
Table 1 - Nosocomial Outbreaks Caused by Leuconostoc mesenteroides subsp. mesenteroides - Volume 14, Number 6-June 2008 -...
Congenital chylothorax‐prenatal ultrasonic diagnosis and successful post partum management<...
Feasibility of ultrasound-guided intranodal lymphangiogram for thoracic duct embolization
Treatment of Chylothorax complicating pulmonary resection with hypertonic glucose Pleurodesis | Journal of Cardiothoracic...
Nontraumatic chylous pleural effusions (chylothorax) and pericardial effusions (chylopericardium) are rare - Resolving the...
A Dasatinib-Induced Chylothorax Persisting After the Discontinuation of Dasatinib
| European Journal of Case Reports in...
Biomarkers Search
Hennekam syndrome - Getting a Diagnosis - Genetic and Rare Diseases Information Center
Noonan syndrome 1 (Concept Id: C4551602)
- MedGen - NCBI
IndexCat
Pleural Catheters Market Surveys, Opportunity, Growth and Forecast by End-use Industry 2021-2031 - PharmiWeb.com
DailyMed - RETEVMO- selpercatinib capsule
Historical Controls
Module IV - Condition-Specific Nutrition Support V.6
Thoracic Non-Hodgkin Lymphoma Imaging: Practice Essentials, Radiography, Computed Tomography
Postoperative chylothorax5
- As previous studies have revealed, postoperative chylothorax is a rare complication of cardiothoracic surgery procedures, especially myocardial revascularization [1-4]. (who.int)
- Postoperative chylothorax, albeit rare, is a serious complication with a high mortality rate, which can approach 50% in untreated patients [4]. (who.int)
- Out of a total of 8252 patients who underwent pulmonary resection (at least lobectomy) at department of thoracic surgery, between June 2008 and December 2015, 58 patients (0.7%) developed postoperative chylothorax. (biomedcentral.com)
- A total of 58 patients (0.7%) developed postoperative chylothorax. (biomedcentral.com)
- 4. Postoperative chylothorax after cardiothoracic surgery in children. (nih.gov)
Differential diagnosis of chylothorax2
Thoracic duct6
- A chylothorax (plural: chylothoraces) refers to the presence of chylous fluid in the pleural space often as a result of obstruction or disruption to the thoracic duct . (radiopaedia.org)
- Treatment of chylothorax: percutaneous catheterization and embolization of the thoracic duct. (radiopaedia.org)
- Injury of such a backflowing LAMLNC is more likely to explain chylothorax as a complication of LIMA harvesting than the injury of the thoracic duct itself since this is more deeply located in this region. (who.int)
- The rarity of chylothorax following LIMA harvest is explained by the usual lymph vessel valve competency of the LAMLNC, which is not always connected with the thoracic duct itself [2]. (who.int)
- Hypertonic glucose pleurodesis performed via the chest drainage tube is a viable treatment option for chylothorax after lung resection, prior to resorting to a thoracoscopic or thoracotomic ductus thoracicus ligation of the thoracic duct leak. (biomedcentral.com)
- Chylothorax, a chylous pleural effusion, is normally a uncommon entity frequently due to malignant tumours or distressing problems for the thoracic duct. (angiogenesis-blog.com)
Chylous4
- Several biochemical parameters of chylous pleural effusion have been identified as important indicators for the diagnosis of chylothorax . (bvsalud.org)
- The present study aimed to evaluate the correlation between the biochemical parameters of chylous pleural effusion and 99mTc- dextran (99mTc-DX) lymphoscintigraphy in diagnosing chylothorax . (bvsalud.org)
- Given the rarity of both chylothorax and chylopericardium5C10, the necessary and adequate anatomic and physiologic conditions for the development of such chylous effusions have not been defined. (angiogenesis-blog.com)
- Central conducting lymphatic anomalies (CCLA) occur when there is a disruption of central lymphatic flow resulting in complications such as non-immune fetal hydrops, chylothorax, chylous ascites, protein-losing enteropathy, other effusions, or lymphedema. (nih.gov)
Congenital Chylothorax2
Effusion1
- Higher pleural effusion triglyceride level and pleural effusion triglyceride / serum triglyceride ratio indicate a positive result in patients with chylothorax on lymphoscintigraphy , with the cutoff values of 2.870 mmol/L and 4.625 aiding in the diagnosis . (bvsalud.org)
Bilateral4
- Less commonly, chylothorax can be bilateral. (radiopaedia.org)
- A total of 120 patients were enrolled in the study, 83 of the patients with unilateral chylothorax , and 37 with bilateral chylothorax . (bvsalud.org)
- 2. Gorham-Stout disease of the mandible, manubrium and cervical spine presenting as bilateral chylothorax. (nih.gov)
- 5. A rare case of Gorham-stout syndrome involving the thoracic spine with progressive bilateral chylothorax: a case report. (nih.gov)
Diagnostic1
- Gross appearance of the fluid is generally considered not a sensitive diagnostic criterion for a identifying chylothorax. (radiopaedia.org)
Transudative4
- Transudative chylothoraces are a rare entity and their management in the presence of multiorgan dysfunction and frailty is complex. (bmj.com)
- A woman in her 90s was investigated during acute hospital admission and found unexpectedly to have a transudative chylothorax secondary to cryptogenic cirrhosis. (bmj.com)
- Case reports surrounding the management of transudative chylothoraces in particular are scarce. (bmj.com)
- Our findings indicated that lymphoscintigraphy results were not associated with exudative and transudative chylothorax (P = 0.597). (bvsalud.org)
Idiopathic1
- 14. Use of octreotide, a long-acting somatostatin analogue, in the treatment of chylothorax of idiopathic etiology. (nih.gov)
Ultrasound1
- Doctors might suspect a chylothorax in a fetus if a routine prenatal ultrasound shows fluid around the baby's lungs. (akronchildrens.org)
Etiology1
- Etiology of chylothorax in 203 patients. (radiopaedia.org)
Pleural fluid1
- Pleural fluid characteristics of chylothorax. (radiopaedia.org)
Lymphatic fluid1
- Chylothorax is caused by lymphatic fluid accumulating in the pleural cavity from the ductus thoracicus. (journalgazett.com)
Chest1
- In this study, we describe the use of hypertonic glucose pleurodesis through the chest drainage tube in eight cases of chylothorax, which resulted in complete and rapid recovery. (biomedcentral.com)
Hydrops1
- She is suffering from Hydrops with chylothorax. (milaap.org)
Underwent1
- Six patients (two women and four men, mean age, 59.2 y [range, 43-74 y]) underwent IL and TDE for chylothorax. (nih.gov)
Diagnosis3
- 4. Büttiker V, Fanconi S, Burger R. Chylothorax in children: guidelines for diagnosis and management. (radiopaedia.org)
- Chylothorax: aetiology, diagnosis and therapeutic options. (radiopaedia.org)
- A diagnosis of chylothorax was made due to lymphatic injury during LIMA harvesting, and the patient was placed on a low-fat diet. (who.int)
Spontaneous2
Chyle2
- When chyle can't get into the blood as it should, it can collect around one or both lungs and form a chylothorax. (akronchildrens.org)
- Lymphoscintigraphy is utilized to assess chylothorax and determine the location of chyle leakage . (bvsalud.org)
Somatostatin1
- In some cases, chylothorax is treated by somatostatin, and operative treatment remains an option for resistant chylothorax with no response to conservative medical treatment [1]. (who.int)
Fluid1
- When there's only a little fluid around a lung, a chylothorax may not cause any symptoms. (akronchildrens.org)
Cardiac1
- 19. Octreotide efficacy in the treatment of chylothoraces following cardiac surgery in infants and children. (nih.gov)
Conservative treatment1
- Late presenting chylothorax responds more readily to conservative treatment as the leak volume is smaller and healing is more likely [3]. (who.int)
Severe2
20181
- Our overview of the books regarding chylothorax and chylopericardium connected with cll between 2005 and 2018 (that's, since the survey from Dib et al .6) revealed 15 reviews of chylothorax and non-e of chylopericardium. (angiogenesis-blog.com)
Clinical1
- Chylothorax is a condition that can be challenging to diagnose due to its nonspecific clinical presentation. (bvsalud.org)
Leak1
- A chylothorax caused by a leak in the lymphatic system may heal on its own. (akronchildrens.org)
Efficacy1
- To retrospectively assess the efficacy of hypertonic glucose pleurodesis for treatment of chylothorax after pulmonary resection. (biomedcentral.com)
Disease5
- 3. 99mTc-SC lymphoscintigraphy and SPECT/CT findings in a case report of Gorham-Stout disease presenting with chylothorax and bone pain. (nih.gov)
- 6. Chylothorax From Gorham-Stout Disease. (nih.gov)
- 7. Chylothorax as a debut form of Gorham-Stout disease. (nih.gov)
- 9. Gorham-Stout syndrome: A chylothorax disease with bony destruction: A case report. (nih.gov)
- 11. A New Case and Review of Chylothorax in Generalized Lymphatic Anomaly and Gorham-Stout Disease. (nih.gov)
Findings1
- Lymphoscintigraphy findings in patients with chylothorax: influence of biochemical parameters. (bvsalud.org)
Rare2
Intervention1
- In conclusion, conservative therapy in uncomplicated cases of chylothorax seems to be a favourable option, and surgical intervention should remain as a final choice if conservative therapy fails. (who.int)
Case2
Management1
- Not all chylothoraces have the classically described milky appearances and a high index of suspicion is vital in determining appropriate investigation and management. (bmj.com)
Children1
- 20. Chylothorax in children after congenital heart surgery. (nih.gov)
Cases2
- Chylothorax: a review of 18 cases. (radiopaedia.org)
- showed in their literature review, most cases with early presenting chylothorax respond only to surgical procedures [1]. (who.int)
Patients1
- 9. Schild HH, Strassburg CP, Welz A, Kalff J. Treatment options in patients with chylothorax. (radiopaedia.org)
Treatment remains1
- The optimal method of chylothorax treatment remains controversial. (biomedcentral.com)
Review1
- A contemporary review of chylothorax. (radiopaedia.org)
BACKGROUND1
- BACKGROUND Roux-en-Y gastric bypass (RYGB) decreases energy intake and is, therefore, an effective treatment of obesity. (jci.org)
Show1
- If tests show that a fetus has a chylothorax, doctors will watch the mother's pregnancy carefully. (akronchildrens.org)