Chronobiology Phenomena
Chronobiology Discipline
A multidisciplinary field of research and practice studying the periodicity of biological systems and the application of principles of chronobiology to various therapeutic strategies. Aging, biological rhythms, and cyclic phenomena are included. Statistical, computer-aided mathematical procedures are used to describe, in mathematical terminology, various biological functions over time.
Chronotherapy
The adaptation of therapeutic approaches such as pharmacological (DRUG CHRONOTHERAPY), surgical, radiological, or physical to the known variations in biological RHYTHMICITY, such as CIRCADIAN RHYTHMS. The treatment is aimed at supporting normal rhythms, or modifying the timing of therapy to achieve maximal efficacy and minimal adverse effect.
Efficacy of bright light and sleep/darkness scheduling in alleviating circadian maladaptation to night work. (1/96)
We tested the hypothesis that circadian adaptation to night work is best achieved by combining bright light during the night shift and scheduled sleep in darkness. Fifty-four subjects participated in a shift work simulation of 4 day and 3 night shifts followed by a 38-h constant routine (CR). Subjects received 2,500 lux (Bright Light) or 150 lux (Room Light) during night shifts and were scheduled to sleep (at home in darkened bedrooms) from 0800 to 1600 (Fixed Sleep) or ad libitum (Free Sleep). Dim light melatonin onset (DLMO) was measured before and after the night shifts. Both Fixed Sleep and Bright Light conditions significantly phase delayed DLMO. Treatments combined additively, with light leading to larger phase shifts. Free Sleep subjects who spontaneously adopted consistent sleep schedules adapted better than those who did not. Neither properly timed bright light nor fixed sleep schedules were consistently sufficient to shift the melatonin rhythm completely into the sleep episode. Scheduling of sleep/darkness should play a major role in prescriptions for overcoming shift work-related phase misalignment. (+info)beta(1)-adrenergic antagonists improve sleep and behavioural disturbances in a circadian disorder, Smith-Magenis syndrome. (2/96)
Smith-Magenis syndrome (SMS) is a clinically recognisable contiguous gene syndrome ascribed to interstitial deletions of chromosome 17p11.2. Patients have a phase shift of their circadian rhythm of melatonin with a paradoxical diurnal secretion of the hormone. Serum melatonin levels and day-night behaviour were studied in nine SMS children (aged 4 to 17 years) given acebutolol, a selective beta(1)-adrenergic antagonist (10 mg/kg early in the morning). Cardiac examination, serum melatonin, motor activity recordings, and sleep diaries were monitored before and after drug administration. The present study shows that a single morning dose of acebutolol suppressed the inappropriate secretion of melatonin in SMS. A significant improvement of inappropriate behaviour with increased concentration, delayed sleep onset, increased hours of sleep, and delayed waking were also noted. These results suggest that beta(1)-adrenergic antagonists help to manage hyperactivity, enhance cognitive performance, and reduce sleep disorders in SMS. (+info)Hypothalamic involvement in chronic migraine. (3/96)
OBJECTIVES: Chronic migraine (CM), previously called transformed migraine, is a frequent headache disorder that affects 2%-3% of the general population. Analgesic overuse, insomnia, depression, and anxiety are disorders that are often comorbid with CM. Hypothalamic dysfunction has been implicated in its pathogenesis, but it has never been studied in patients with CM. The aim was to analyze hypothalamic involvement in CM by measurement of melatonin, prolactin, growth hormone, and cortisol nocturnal secretion. METHODS: A total of 338 blood samples (13/patient) from 17 patients with CM and nine age and sex matched healthy volunteers were taken. Melatonin, prolactin, growth hormone, and cortisol concentrations were determined every hour for 12 hours. The presence of comorbid disorders was also evaluated. RESULTS: An abnormal pattern of hypothalamic hormonal secretion was found in CM. This included: (1) a decreased nocturnal prolactin peak, (2) increased cortisol concentrations, (3) a delayed nocturnal melatonin peak in patients with CM, and (4) lower melatonin concentrations in patients with CM with insomnia. Growth hormone secretion did not differ from controls. CONCLUSION: These results support hypothalamic involvement in CM, shown by a chronobiologic dysregulation, and a possible hyperdopaminergic state in patients with CM. Insomnia might be an important variable in the study findings. (+info)Heart rate and energy expenditure of incubating wandering albatrosses: basal levels, natural variation, and the effects of human disturbance. (4/96)
We studied the changes in heart rate (HR) associated with metabolic rate of incubating and resting adult wandering albatrosses (Diomedea exulans) on the Crozet Islands. Metabolic rates of resting albatrosses fitted with external HR recorders were measured in a metabolic chamber to calibrate the relationship between HR and oxygen consumption (V(O(2))) (V(O(2))=0.074 x HR+0.019, r(2)=0.567, P<0.001, where V(O(2)) is in ml kg(-1) min(-1) and HR is in beats min(-1)). Incubating albatrosses were then fitted with HR recorders to estimate energy expenditure of albatrosses within natural field conditions. We also examined the natural variation in HR and the effects of human disturbance on nesting birds by monitoring the changes in HR. Basal HR was positively related to the mass of the individual. The HR of incubating birds corresponded to a metabolic rate that was 1.5-fold (males) and 1.8-fold (females) lower than basal metabolic rate (BMR) measured in this and a previous study. The difference was probably attributable to birds being stressed while they were held in the metabolic chamber or wearing a mask. Thus, previous measurements of metabolic rate under basal conditions or for incubating wandering albatrosses are likely to be overestimates. Combining the relationship between HR and metabolic rate for both sexes, we estimate that wandering albatrosses expend 147 kJ kg(-1) day(-1) to incubate their eggs. In addition, the cost of incubation was assumed to vary because (i) HR was higher during the day than at night, and (ii) there was an effect of wind chill (<0 degrees C) on basal HR. The presence of humans in the vicinity of the nest or after a band control was shown to increase HR for extended periods (2-3 h), suggesting that energy expenditure was increased as a result of the disturbance. Lastly, males and females reacted differently to handling in terms of HR response: males reacted more strongly than females before handling, whereas females took longer to recover after being handled. (+info)Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice. (5/96)
Mammalian free-running circadian rhythms are entrained to the external light/dark cycle by photic signaling to the suprachiasmatic nuclei via the retinohypothalamic tract (RHT). We investigated the circadian entrainment and clock properties of math5-/- mutant mice. math5 is a critical regulator of retinal ganglion cell development; math5-/- mice show severe optic nerve hypoplasia. By anterograde cholera toxin B tracing, we find that math5-/- mice do not develop an identifiable RHT pathway. This appears to be attributable to agenesis or dysgenesis of the majority of RHT-projecting retinal ganglion cells. math5-/- mice display free-running circadian rhythms with a period approximately 1 hr longer than B6/129 controls (24.43 +/- 0.10 vs 23.62 +/- 0.19 hr; p < 0.00001). The free-running period of heterozygote mice is indistinguishable from that of controls. math5-/- mice show no entrainment to light/dark cycles, whereas heterozygote mice show normal entrainment to both 12 hr light/dark cycles and to a 1 hr skeletal photoperiod. math5-/- mice show reduced ability to entrain their rhythms to the nonphotic time cue of restricted running wheel access but demonstrate both free-running behavior and entrained anticipation of wheel unlocking in these conditions, suggesting the presence of a second diurnal oscillatory system in math5-/- animals. These results demonstrate that retinal ganglion cell input is not necessary for the development of a free-running circadian timekeeping system in the suprachiasmatic nucleus but is important for both photic entrainment and determination of the free-running period. (+info)Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo. (6/96)
BACKGROUND: Decreased heart rate variability (HRV) and increased blood pressure variability (BPV), determined in part by nitric oxide (NO)-dependent endothelial dysfunction, are correlated with adverse prognosis in cardiovascular diseases. We examined potential alterations in BPV and HRV in genetically dyslipidemic, apolipoprotein (apo) E-/-, and control mice and the effect of chronic statin treatment on these parameters in relation to their NO synthase (NOS)-modifying properties. METHODS AND RESULTS: BP and HR were recorded in unrestrained, nonanesthetized mice with implanted telemetry devices with or without rosuvastatin. Cardiac and aortic expression of endothelial NOS and caveolin-1 were measured by immunoblotting. Both systolic BP and HR were elevated in apoE-/- mice, with abolition of their circadian cycles. Spectral analysis showed an increase in their systolic BPV in the very-low-frequency (+17%) band and a decrease in HRV in the high-frequency (-57%) band, reflecting neurohumoral and autonomic dysfunction. Decreased sensitivity to acute injection of atropine or an NOS inhibitor indicated basal alterations in both parasympathetic and NOS regulatory systems in apoE-/- mice. Aortic caveolin-1 protein, an inhibitor of endothelial NOS, was also increased in these mice by 2.0-fold and correlated positively with systolic BPV in the very-low-frequency band. Rosuvastatin treatment corrected the hemodynamic and caveolin-1 expression changes despite persisting elevated plasma cholesterol levels. CONCLUSIONS: Rosuvastatin decreases caveolin-1 expression and promotes NOS function in apoE-/-, dyslipidemic mice in vivo, with concurrent improvements in BPV and HRV. This highlights the beneficial effects of rosuvastatin on cardiovascular function beyond those attributed to lipid lowering. (+info)An abrupt shift in the day/night cycle causes desynchrony in the mammalian circadian center. (7/96)
The suprachiasmatic nucleus (SCN) is the neuroanatomical locus of the mammalian circadian pacemaker. Here we demonstrate that an abrupt shift in the light/dark (LD) cycle disrupts the synchronous oscillation of circadian components in the rat SCN. The phases of the RNA cycles of the period genes Per1 and Per2 and the cryptochrome gene Cry1 shifted rapidly in the ventrolateral, photoreceptive region of the SCN, but were relatively slow to shift in the dorsomedial region. During the period of desynchrony, the animals displayed increased nighttime rest, the timing of which was inversely correlated with the expression of Per1 mRNA in the dorsomedial SCN. Molecular resynchrony required approximately 6 d after a 10 hr delay and 9 approximately 13 d after a 6 hr advance of the LD cycle and was accompanied by the reemergence of normal rest-activity patterns. This dissociation and slow resynchronization of endogenous oscillators within the SCN after an LD cycle shift suggests a mechanism for the physiological symptoms that constitute jet lag. (+info)Loss of circadian rhythm of blood pressure following acute stroke. (8/96)
BACKGROUND: Epidemiology of acute stroke in developing countries differs from that in the developed world, for example, the age at stroke, risk factors, subtypes of stroke and prognosis. Hypertension remains a dominant risk factor and prognostic indicator in patients with stroke in all communities. The risk of stroke is directly related to elevations of blood pressure. A number of clinical studies have shown that the control of hypertension leads to a reduction in the incidence of stroke in a community. However there is still considerable controversy surrounds the changes in blood pressure in various subtypes of strokes and problem of management of elevated BP after stroke. We studied the circadian rhythm of blood pressure in patients following acute stroke. METHODS: To study the circadian rhythm of blood pressure, fifty consecutive patients with an acute stroke who were admitted to medical emergency within 120 hours of onset were included in the study. After a detailed history and clinical examination, a continuous blood pressure monitor (Spacelab 90207) was attached on the side ipsilateral to intracranial lesion (unaffected arm). The blood pressure was recorded for 24 hours at 15 minutes interval during daytime (6.00 am-6.00 pm) and 20 minutes interval overnight (6 pm to 6 am). RESULTS: Risk factors for stroke in 50 patients included hypertension in 31(62%), diabetes mellitus in 4 (8%), smoking in 13 (26%) and previous history of transient ischemic attack in 7 (14%) patients. Mean systolic pressure and diastolic pressure at admission were higher in patients with hemorrhagic stroke -29 patients (177 +/- 24 mmHg and 105 +/- 19 mmHg respectively) compared to patients with ischemic strokes-21 patients (150 +/- 36 mm Hg and 89 +/- 18 mm Hg respectively, p value <0.01 in both comparisons). The normal diurnal variation in blood pressure (night time dipping of more than 10%) was abolished in 44 (88%) of patients. Out of 44 nondippers, 29 patients showed reverse dipping i.e. rise of BP during night time compared to day time levels. None of the risk factors, clinical or laboratory variables, type of stroke or blood pressure changes differed significantly between these two groups. CONCLUSIONS: Therefore, we showed a pathologically reduced or abolished circadian BP variation after stroke. Absence of normal dipping results in a higher 24 hour blood pressure load and may have more target organ damage than those with normal diurnal variation of blood pressure. (+info)'Chronobiology phenomena' refer to the regular and cyclic variations in biological functions and behaviors that occur over time, typically with a period of approximately 24 hours, influenced by the Earth's rotation and governed by an internal circadian clock.
Chronobiology is the study of biological rhythms and their synchronization with environmental cycles. It examines how various biological processes in living organisms, including humans, are regulated by endogenous (internal) and exogenous (external) factors that recur over a specific time period. These rhythmic phenomena are known as circadian, ultradian, and infradian rhythms.
Circadian rhythms have a periodicity of approximately 24 hours and regulate many physiological processes such as sleep-wake cycles, body temperature, hormone secretion, and metabolism. Ultradian rhythms are shorter than 24 hours and include processes like heart rate variability, brain wave activity during sleep, and digestive enzyme release. Infradian rhythms have a longer periodicity, ranging from days to years, and include menstrual cycles in women and seasonal variations in animals.
Chronobiology phenomena are crucial for understanding the timing of various physiological processes and how they can be influenced by external factors like light-dark cycles, social cues, and lifestyle habits. This knowledge has applications in fields such as medicine, agriculture, and environmental science.
Chronobiology disorders are disruptions in the circadian rhythms, the internal biological clock system that regulates various physiological processes, which can lead to sleep-wake cycle disturbances, mood changes, and other health issues. Examples include Delayed Sleep Phase Syndrome (DSPS), Advanced Sleep Phase Syndrome (ASPS), Non-24-Hour Sleep-Wake Rhythm Disorder, and irregular sleep-wake rhythm disorder.
Chronobiology disorders are a group of conditions that involve disruptions in the body's internal biological clock, which regulates various physiological processes such as sleep-wake cycles, hormone release, and metabolism. These disorders can result in a variety of symptoms, including difficulty sleeping, changes in mood and energy levels, and problems with cognitive function.
Some common examples of chronobiology disorders include:
1. Delayed Sleep Phase Syndrome (DSPS): This condition is characterized by a persistent delay in the timing of sleep, so that an individual's preferred bedtime is significantly later than what is considered normal. As a result, they may have difficulty falling asleep and waking up at socially acceptable times.
2. Advanced Sleep Phase Syndrome (ASPS): In this condition, individuals experience an earlier-than-normal timing of sleep, so that they become sleepy and wake up several hours earlier than most people.
3. Non-24-Hour Sleep-Wake Rhythm Disorder: This disorder is characterized by a persistent mismatch between the individual's internal biological clock and the 24-hour day, resulting in irregular sleep-wake patterns that can vary from day to day.
4. Irregular Sleep-Wake Rhythm Disorder: In this condition, individuals experience a lack of consistent sleep-wake patterns, with multiple periods of sleep and wakefulness throughout the 24-hour day.
5. Shift Work Sleep Disorder: This disorder is caused by the disruption of normal sleep-wake patterns due to working irregular hours, such as night shifts or rotating schedules.
6. Jet Lag Disorder: This condition occurs when an individual travels across time zones and experiences a temporary mismatch between their internal biological clock and the new local time.
Treatment for chronobiology disorders may include lifestyle changes, such as adjusting sleep schedules and exposure to light, as well as medications that can help regulate sleep-wake cycles. In some cases, cognitive-behavioral therapy (CBT) may also be helpful in managing these conditions.
Chronobiology is a interdisciplinary field of biology that studies the rhythmic patterns, cycles and changes in biological systems and organisms, including the effects of light and darkness on physiological processes, in order to understand and optimize health, well-being, and performance.
Chronobiology is the scientific discipline that studies the rhythmic patterns and cycles in living organisms (including humans) in relation to their environment, particularly in relation to the 24-hour day and longer seasonal cycles. It examines how various physiological processes and behaviors are synchronized with these external time cues, also known as zeitgebers.
Examples of areas studied within chronobiology include:
1. Circadian rhythms: These are the internal biological clocks that regulate many aspects of human physiology and behavior over a 24-hour period, such as sleep-wake cycles, body temperature, hormone release, and metabolism.
2. Seasonal affective disorder (SAD): This is a type of depression that occurs in response to changes in seasons, typically during the winter months when there is less natural light available.
3. Jet lag: This is a temporary disruption of circadian rhythms caused by rapid travel across time zones, resulting in symptoms such as fatigue, insomnia, and difficulty concentrating.
4. Shift work disorder: This is a condition that affects people who work irregular hours or night shifts, causing disturbances in sleep patterns and other physiological processes.
5. Menstrual cycle regulation: Chronobiology studies the hormonal changes and rhythms associated with the menstrual cycle to better understand reproductive health and potential treatments for related disorders.
Overall, chronobiology seeks to understand how these internal and external time cues interact and influence various aspects of human health and disease.
Chronotherapy is a medical treatment strategy that aligns the timing of medication or therapeutic interventions with the body's internal circadian rhythms to optimize efficacy and minimize side effects.
Chronotherapy is a medical treatment strategy that involves adjusting the timing of medication or other treatments based on the body's internal clock or circadian rhythms. The goal of chronotherapy is to optimize the effectiveness and minimize the side effects of treatments by administering them at specific times when they are most likely to be beneficial and well-tolerated.
For example, certain medications may be more effective when given at night because the body's metabolism slows down during sleep, allowing the drug to remain in the system longer. Similarly, some cancer treatments may be more effective when administered in the morning or evening based on the patient's circadian rhythms.
Chronotherapy can also involve adjusting lifestyle factors such as diet, exercise, and light exposure to help regulate the body's internal clock and improve overall health. This approach has been shown to be effective in treating a variety of conditions, including insomnia, depression, asthma, and cardiovascular disease.
'Circadian Rhythm' refers to an endogenous, approximately 24-hour biological rhythm that regulates various physiological processes such as sleep-wake cycle, body temperature, and hormone secretion, primarily controlled by a group of genes and environmental cues like light and darkness.
A circadian rhythm is a roughly 24-hour biological cycle that regulates various physiological and behavioral processes in living organisms. It is driven by the body's internal clock, which is primarily located in the suprachiasmatic nucleus (SCN) of the hypothalamus in the brain.
The circadian rhythm controls many aspects of human physiology, including sleep-wake cycles, hormone secretion, body temperature, and metabolism. It helps to synchronize these processes with the external environment, particularly the day-night cycle caused by the rotation of the Earth.
Disruptions to the circadian rhythm can have negative effects on health, leading to conditions such as insomnia, sleep disorders, depression, bipolar disorder, and even increased risk of chronic diseases like cancer, diabetes, and cardiovascular disease. Factors that can disrupt the circadian rhythm include shift work, jet lag, irregular sleep schedules, and exposure to artificial light at night.
Sleep in bipolar disorder
Wirz-Justice, A. (2003). "Chronobiology and mood disorders". Dialogues in Clinical Neuroscience. 5 (4): 315-325. doi:10.31887/ ... Bipolar disorder is known to have a high heritability. Therefore, sleep disturbances in bipolar disorder could also have a ... Sleep is known to play an important role in the etiology and maintenance of bipolar disorder. Patients with bipolar disorder ... The diagnosis of a bipolar disorder is linked to various sleep disorders. Comorbidities include insomnia and hypersomnia. Other ...
Phase response curve
Chronobiology Circadian rhythm sleep disorder Delayed sleep phase disorder Canavier CC (2006). "Phase response curve". ... light therapy is used as treatment for several affective disorders including seasonal affective disorder (SAD). In 2002 Brown ... Various sleep disorders and externals stresses (such as jet lag) can interfere with this. People with non-24-hour sleep-wake ... Lewy A, Sack R, Fredrickson R (1983). "The use of bright light in the treatment of chronobiologic sleep and mood disorders: The ...
Diurnal mood variation
Although diurnal mood variation is a prevalent pattern observed in various mood disorders, there exists a gap in the literature ... Articles with short description, Short description is different from Wikidata, Depression (mood), Psychiatry, Chronobiology, ... According to the diagnostic criteria outlined in The Diagnostic and Statistical Manual of Mental Disorders (DSM) and The ... Neurocircuitry and Neuroplasticity Abnormalities in Mood and Anxiety Disorders. 62 (5): 438-445. doi:10.1016/j.biopsych.2006.09 ...
Seasonal affective disorder
"Bipolar disorder with seasonal pattern: clinical characteristics and gender influences". Chronobiology International. 30 (9): ... With seasonal pattern is a specifier for bipolar and related disorders, including bipolar I disorder and bipolar II disorder. ... Seasonal affective disorder (SAD) is a mood disorder subset in which people who typically have normal mental health throughout ... Seasonal Affective Disorder at Curlie What is Bipolar Disorder? at HopeQure USA National Institute of Mental Health webpages ...
Metabolic syndrome
... disrupted chronobiology/sleep, mood disorders/psychotropic medication use, and excessive alcohol use. The pathogenic role ... The syndrome is thought to be caused by an underlying disorder of energy utilization and storage. The cause of the syndrome is ... Reproductive disorders (such as polycystic ovary syndrome in women of reproductive age), and erectile dysfunction or decreased ... Lipodystrophic disorders in general are associated with metabolic syndrome. Both genetic (e.g., Berardinelli-Seip congenital ...
Chronobiotic
Circadian rhythm sleep disorder Chronobiology Sleep medicine (Articles with short description, Short description is different ... Sleep and sleep disorders: a neuropsychopharmacological approach. Georgetown, Tex., U.S.A: Landes Bioscience/Eurekah.com. ISBN ...
Biology of bipolar disorder
"The CLOCK gene and mood disorders: a case-control study and meta-analysis". Chronobiology International. 28 (9): 825-33. doi: ... Biology of bipolar disorder, Mood disorders, Causes of mental disorders, Biological psychiatry, Bipolar disorder). ... Bipolar disorder is an affective disorder characterized by periods of elevated and depressed mood. The cause and mechanism of ... Grunze, H. "Bipolar Disorder". In Zigmond, M; Rowland, L; Coyle, J (eds.). Neurobiology of Brain Disorder: Biological Basis of ...
Delayed sleep phase disorder
... a circadian rhythm sleep disorder". Chronobiology International. 22 (3): 559-70. doi:10.1081/CBI-200062410. PMID 16076654. ... "Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, ... There have been cases of DSPD developing into non-24-hour sleep-wake disorder, a severe and debilitating disorder in which the ... It has been named as one of the sleep disorders most commonly misdiagnosed as a primary psychiatric disorder. DSPD is often ...
Advanced sleep phase disorder
Johnson, Carl H. (2013). "Entrainment of Circadian Programs" (PDF). Chronobiology International. 20 (5): 741-774. doi:10.1081/ ... "Circadian Rhythm Sleep Disorders: Part II, Advanced Sleep Phase Disorder, Delayed Sleep Phase Disorder, Free-Running Disorder, ... Advanced Sleep Phase Disorder (ASPD), also known as the advanced sleep-phase type (ASPT) of circadian rhythm sleep disorder, is ... Delayed sleep phase disorder Irregular sleep-wake rhythm Non-24-hour sleep-wake disorder Dodson, Ehren R.; Zee, Phyllis C (2010 ...
Familial sleep traits
Chronobiology Irregular sleep-wake rhythm Non-24-hour sleep-wake disorder Shift work sleep disorder Jet lag Madrid-Valero JJ, ... Some of these circadian disorders include Advanced Sleep Phase Disorder (ASPD) and Delayed Sleep Phase Disorder (DSPD). ... The disorder can manifest any time from age 18 to 60, but the average age of affected individuals is 50 years old. The disorder ... The disorder is caused by a mutation of the PRNP gene resulting in the creation of a prion. These prions result in ...
Non-24-hour sleep-wake disorder
Chronobiology International. 19 (3): 649-658. doi:10.1081/CBI-120004546. PMID 12069043. S2CID 24038952. Rajaratnam, S. M. W., ... "Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, ... Circadian rhythm sleep disorder, the parent spectrum of sleep disorders including non-24-hour sleep-wake disorder. Delayed ... the disorder is also known as: non-24-hour sleep-wake syndrome or disorder, free-running disorder (FRD),[citation needed] ...
Light effects on circadian rhythm
Chronobiology Circadian advantage Circadian clock Circadian oscillator Circadian rhythm disorders Electronic media and sleep ... Seasonal affective disorder creates a model in which decreased day length during autumn and winter increases depressive ... Reviews in Endocrine & Metabolic Disorders. 10 (4): 301-10. doi:10.1007/s11154-009-9121-9. PMID 19777352. S2CID 8653740. van ... and depressive symptoms in this disorder. Light seems to have therapeutic antidepressant effects when an organism is exposed to ...
Entrainment (chronobiology)
ASPD and non-24-hour sleep-wake disorder are improperly entrained to light/dark. Crepuscular - Animals active at twilight (i.e ... In the study of chronobiology, entrainment occurs when rhythmic physiological or behavioral events match their period to that ... "Basic Science Review on Circadian Rhythm Biology and Circadian Sleep Disorders" (PDF). Annals Academy Med Singapore. 37 (8): ...
Circadian rhythm
... such as Advanced sleep phase disorder Delayed sleep phase disorder Non-24-hour sleep-wake disorder Chronobiology ... A number of other disorders, such as bipolar disorder and some sleep disorders such as delayed sleep phase disorder (DSPD), are ... Maung SC, El Sara A, Chapman C, Cohen D, Cukor D (May 2016). "Sleep disorders and chronic kidney disease". World Journal of ... In clinical settings, an abnormal circadian rhythm in humans is known as a circadian rhythm sleep disorder. While there are ...
Irregular sleep-wake rhythm disorder
Advanced sleep phase syndrome Chronobiology Circadian rhythm Delayed sleep phase disorder "Irregular sleep-wake syndrome: ... "Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, ... The current formally correct name of the disorder is Irregular Sleep Wake Rhythm Disorder. This disorder has been referred to ... Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder ( ...
Computer vision syndrome
Amber-tinted lenses have been shown to affect the circadian rhythm and treat delayed sleep phase disorder. According to the US ... Chronobiology International. 33 (8): 1037-1044. doi:10.1080/07420528.2016.1194289. PMID 27322730. S2CID 35562927. Burkhart, ... "Wearing blue light-blocking glasses in the evening advances circadian rhythms in the patients with delayed sleep phase disorder ... Chronobiology International. 26 (8): 1602-1612. doi:10.3109/07420520903523719. PMID 20030543. S2CID 145296760. Becoming a ...
Suprachiasmatic nucleus
Chronobiology Photosensitive ganglion cell Sense of time Retinohypothalamic tract Shift work sleep disorder Non-24-hour sleep- ... Disruptions or damage to the SCN has been associated with different mood disorders and sleep disorders, suggesting the ... Major depressive disorder (MDD) has been associated with altered circadian rhythms. Patients with MDD have weaker rhythms that ... Patients with AD experience insomnia, hypersomnia, and other sleep disorders as a result of the degeneration of the SCN and ...
Circadian rhythm sleep disorder
Chronobiology Familial sleep traits Light effects on circadian rhythm Phase response curve Sleep diary Sleep medicine Dagan, ... Delayed sleep phase disorder, advanced sleep phase disorder, non-24-hour sleep-wake disorder and irregular sleep-wake rhythm ... Advanced Sleep Phase Disorder, Delayed Sleep Phase Disorder, Free-Running Disorder, and Irregular Sleep-Wake Rhythm. PDF, 18 ... Circadian rhythm sleep disorders (CRSD), also known as circadian rhythm sleep-wake disorders (CRSWD), are a family of sleep ...
List of cycles
Bipolar disorder - Cardiopulmonary resuscitation - Calvin-Benson cycle - Cell cycle - Chronobiology - Citric acid cycle - ...
Morningness-eveningness questionnaire
Circadian rhythm sleep disorder Horne, JA, Östberg O (1976). "A self-assessment questionnaire to determine morningness- ... Chronobiology International. 28 (3): 238-247. doi:10.3109/07420528.2010.549599. PMC 3818690. PMID 21452919. Hur YM, Bouchard TJ ... eveningness in human circadian rhythms". International Journal of Chronobiology. 4 (2): 97-110. PMID 1027738.{{cite journal}}: ...
Depopulation of cockroaches in post-Soviet states
Colony collapse disorder, bees Исчезновение тараканов на Белгородчине не связано с радиацией :: ИА Бел.Ру - Новости Белгорода ... Ozone holes may also lead to abnormal chronobiology in cockroaches. Internal competitions between cockroaches may decrease the ...
Sato Honma
"International ChronoBiology Summer School in Florida from May 26-29, 2020 , SRBR: Society for Research on Biological Rhythms". ... She is currently the director at the Center for Sleep and Circadian Rhythm Disorders at Sapporo Hanazono Hospital and works as ... Sato Honma and Ken-ichi Honma had a chronobiology laboratory for over 30 years at Hokkaido University, and many of the students ... She was one of the instructors for the International Chronobiology Summer School, in Beijing in 2016, and that in Munich 2019. ...
Jürgen Aschoff
In: Trends in Chronobiology, ed. Hekkens W, Th JM, Jerkhof GA and Rhietveld WJ, Pergamon Press, Oxford and New York, pp. 149- ... His later work was more applicable to pathologies, such as psychiatric disorders and dangers of shift work schedules, which can ... Together with Erwin Bünning and Colin Pittendrigh, he is considered to be a co-founder of the field of chronobiology. Aschoff's ... This discovery has become the foundation for our understanding of many medical problems such as aging, sleep disorders, and jet ...
Lynne Lamberg
Lamberg, Lynne (2000). Skin Disorders (21st Century Health and Wellness). New York: Chelsea House Publishing. ISBN 0791059839. ... Lamberg, Lynne (November 1, 2000). Bodyrhythms: Chronobiology and Peak Performance. iUniverse. ISBN 0595147852.{{cite book}}: ... Lamberg, Lynne (1994). Bodyrhythms: Chronobiology and Peak Performance. William Morrow & Co. ISBN 0877959919. Cartwright, ... chronobiology, chronomedicine, chronotherapy and chronorecord-keeping. 'We pay more attention to watches we wear on our wrists ...
Night owl
Some night owls with great difficulty adopting normal sleeping and waking times may have delayed sleep phase disorder. Morning ... Chronobiology (2004) McCullough, David (1992). Truman. Simon & Schuster. p. 508. ISBN 978-0671456542. Sleep Discrimination ... Laura H. Smith/Charles H. Elliott, Seasonal Affective Disorder for Dummies (2007) p. 73 Maestripieri, Dario (2014-01-01). " ... the study of sleep cycles and other time-dependent biological systems Circadian rhythm sleep disorder Insomnia - the inability ...
Johanna Meijer
... including Advanced sleep phase disorder Delayed sleep phase disorder Non-24-hour sleep-wake disorder Chronotherapy Sleep Sleep ... Meijer continues her study of circadian rhythms and chronobiology today as a Professor and Head of Neurophysiology Group at the ... Johanna H. Meijer (born 26 March 1959) is a Dutch scientist who has contributed significantly to the field of chronobiology. ... 1993: "Aschoff's Rule, a prize for eminent contributions in Chronobiology supporting the interdisciplinary spirit of the field ...
Jrk
... anxiety disorder, and substance use disorder. Clock gene Period (gene) Cycle (gene) Timeless (gene) Chronobiology Oscillating ... deficit/hyperactivity disorder, major depressive disorder, bipolar disorder, ... Schuch JB, Genro JP, Bastos CR, Ghisleni G, Tovo-Rodrigues L (March 2018). "The role of CLOCK gene in psychiatric disorders: ... Mammalian mutations in the Clock gene have been found to result in autism spectrum disorder, schizophrenia, attention‐ ...
Thomas Wehr
Wehr and colleague Anna Wirz-Justice were awarded the Anna Monika Prize for their work in the chronobiology of depressive ... Wehr and colleague Norman E. Rosenthal are credited with identifying and describing Seasonal Affective Disorder (SAD) and ...
Melatonin
... in the treatment of sleep disorders such as insomnia and circadian rhythm sleep disorders like delayed sleep phase disorder, ... Chronobiology International. 21 (1): 1-25. doi:10.1081/CBI-120027984. PMID 15129821. S2CID 42725506. Foster RG (June 2020). " ... jet lag disorder, and shift work disorder. Besides melatonin, certain synthetic melatonin receptor agonists like ramelteon, ... Riha RL (November 2018). "The use and misuse of exogenous melatonin in the treatment of sleep disorders". Curr Opin Pulm Med. ...
Shift work
... metabolic disorders, gastrointestinal disorders, musculoskeletal disorders, and reproductive disorders. Shift work also can ... Chronobiology International. 29 (9): 1153-1175. doi:10.3109/07420528.2012.719971. PMID 23004349. S2CID 7565248. Ftouni, Suzanne ... Shift work sleep disorder is a circadian rhythm sleep disorder characterized by insomnia, excessive sleepiness, or both. Shift ... Shift work sleep disorder also creates a greater risk for human error at work. Shift work disrupts cognitive ability and ...