Biological systems as affected by time. Aging, biological rhythms, and cyclic phenomena are included. Statistical, computer-aided mathematical procedures are used to describe, in mathematical terminology, various biological functions over time.
Disruptions of the rhythmic cycle of bodily functions or activities.
A multidisciplinary field of research and practice studying the periodicity of biological systems and the application of principles of chronobiology to various therapeutic strategies. Aging, biological rhythms, and cyclic phenomena are included. Statistical, computer-aided mathematical procedures are used to describe, in mathematical terminology, various biological functions over time.
The adaptation of therapeutic approaches such as pharmacological (DRUG CHRONOTHERAPY), surgical, radiological, or physical to the known variations in biological RHYTHMICITY, such as CIRCADIAN RHYTHMS. The treatment is aimed at supporting normal rhythms, or modifying the timing of therapy to achieve maximal efficacy and minimal adverse effect.
The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs and stimuli, hormone secretion, sleeping, and feeding.

Efficacy of bright light and sleep/darkness scheduling in alleviating circadian maladaptation to night work. (1/96)

We tested the hypothesis that circadian adaptation to night work is best achieved by combining bright light during the night shift and scheduled sleep in darkness. Fifty-four subjects participated in a shift work simulation of 4 day and 3 night shifts followed by a 38-h constant routine (CR). Subjects received 2,500 lux (Bright Light) or 150 lux (Room Light) during night shifts and were scheduled to sleep (at home in darkened bedrooms) from 0800 to 1600 (Fixed Sleep) or ad libitum (Free Sleep). Dim light melatonin onset (DLMO) was measured before and after the night shifts. Both Fixed Sleep and Bright Light conditions significantly phase delayed DLMO. Treatments combined additively, with light leading to larger phase shifts. Free Sleep subjects who spontaneously adopted consistent sleep schedules adapted better than those who did not. Neither properly timed bright light nor fixed sleep schedules were consistently sufficient to shift the melatonin rhythm completely into the sleep episode. Scheduling of sleep/darkness should play a major role in prescriptions for overcoming shift work-related phase misalignment.  (+info)

beta(1)-adrenergic antagonists improve sleep and behavioural disturbances in a circadian disorder, Smith-Magenis syndrome. (2/96)

Smith-Magenis syndrome (SMS) is a clinically recognisable contiguous gene syndrome ascribed to interstitial deletions of chromosome 17p11.2. Patients have a phase shift of their circadian rhythm of melatonin with a paradoxical diurnal secretion of the hormone. Serum melatonin levels and day-night behaviour were studied in nine SMS children (aged 4 to 17 years) given acebutolol, a selective beta(1)-adrenergic antagonist (10 mg/kg early in the morning). Cardiac examination, serum melatonin, motor activity recordings, and sleep diaries were monitored before and after drug administration. The present study shows that a single morning dose of acebutolol suppressed the inappropriate secretion of melatonin in SMS. A significant improvement of inappropriate behaviour with increased concentration, delayed sleep onset, increased hours of sleep, and delayed waking were also noted. These results suggest that beta(1)-adrenergic antagonists help to manage hyperactivity, enhance cognitive performance, and reduce sleep disorders in SMS.  (+info)

Hypothalamic involvement in chronic migraine. (3/96)

OBJECTIVES: Chronic migraine (CM), previously called transformed migraine, is a frequent headache disorder that affects 2%-3% of the general population. Analgesic overuse, insomnia, depression, and anxiety are disorders that are often comorbid with CM. Hypothalamic dysfunction has been implicated in its pathogenesis, but it has never been studied in patients with CM. The aim was to analyze hypothalamic involvement in CM by measurement of melatonin, prolactin, growth hormone, and cortisol nocturnal secretion. METHODS: A total of 338 blood samples (13/patient) from 17 patients with CM and nine age and sex matched healthy volunteers were taken. Melatonin, prolactin, growth hormone, and cortisol concentrations were determined every hour for 12 hours. The presence of comorbid disorders was also evaluated. RESULTS: An abnormal pattern of hypothalamic hormonal secretion was found in CM. This included: (1) a decreased nocturnal prolactin peak, (2) increased cortisol concentrations, (3) a delayed nocturnal melatonin peak in patients with CM, and (4) lower melatonin concentrations in patients with CM with insomnia. Growth hormone secretion did not differ from controls. CONCLUSION: These results support hypothalamic involvement in CM, shown by a chronobiologic dysregulation, and a possible hyperdopaminergic state in patients with CM. Insomnia might be an important variable in the study findings.  (+info)

Heart rate and energy expenditure of incubating wandering albatrosses: basal levels, natural variation, and the effects of human disturbance. (4/96)

We studied the changes in heart rate (HR) associated with metabolic rate of incubating and resting adult wandering albatrosses (Diomedea exulans) on the Crozet Islands. Metabolic rates of resting albatrosses fitted with external HR recorders were measured in a metabolic chamber to calibrate the relationship between HR and oxygen consumption (V(O(2))) (V(O(2))=0.074 x HR+0.019, r(2)=0.567, P<0.001, where V(O(2)) is in ml kg(-1) min(-1) and HR is in beats min(-1)). Incubating albatrosses were then fitted with HR recorders to estimate energy expenditure of albatrosses within natural field conditions. We also examined the natural variation in HR and the effects of human disturbance on nesting birds by monitoring the changes in HR. Basal HR was positively related to the mass of the individual. The HR of incubating birds corresponded to a metabolic rate that was 1.5-fold (males) and 1.8-fold (females) lower than basal metabolic rate (BMR) measured in this and a previous study. The difference was probably attributable to birds being stressed while they were held in the metabolic chamber or wearing a mask. Thus, previous measurements of metabolic rate under basal conditions or for incubating wandering albatrosses are likely to be overestimates. Combining the relationship between HR and metabolic rate for both sexes, we estimate that wandering albatrosses expend 147 kJ kg(-1) day(-1) to incubate their eggs. In addition, the cost of incubation was assumed to vary because (i) HR was higher during the day than at night, and (ii) there was an effect of wind chill (<0 degrees C) on basal HR. The presence of humans in the vicinity of the nest or after a band control was shown to increase HR for extended periods (2-3 h), suggesting that energy expenditure was increased as a result of the disturbance. Lastly, males and females reacted differently to handling in terms of HR response: males reacted more strongly than females before handling, whereas females took longer to recover after being handled.  (+info)

Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice. (5/96)

Mammalian free-running circadian rhythms are entrained to the external light/dark cycle by photic signaling to the suprachiasmatic nuclei via the retinohypothalamic tract (RHT). We investigated the circadian entrainment and clock properties of math5-/- mutant mice. math5 is a critical regulator of retinal ganglion cell development; math5-/- mice show severe optic nerve hypoplasia. By anterograde cholera toxin B tracing, we find that math5-/- mice do not develop an identifiable RHT pathway. This appears to be attributable to agenesis or dysgenesis of the majority of RHT-projecting retinal ganglion cells. math5-/- mice display free-running circadian rhythms with a period approximately 1 hr longer than B6/129 controls (24.43 +/- 0.10 vs 23.62 +/- 0.19 hr; p < 0.00001). The free-running period of heterozygote mice is indistinguishable from that of controls. math5-/- mice show no entrainment to light/dark cycles, whereas heterozygote mice show normal entrainment to both 12 hr light/dark cycles and to a 1 hr skeletal photoperiod. math5-/- mice show reduced ability to entrain their rhythms to the nonphotic time cue of restricted running wheel access but demonstrate both free-running behavior and entrained anticipation of wheel unlocking in these conditions, suggesting the presence of a second diurnal oscillatory system in math5-/- animals. These results demonstrate that retinal ganglion cell input is not necessary for the development of a free-running circadian timekeeping system in the suprachiasmatic nucleus but is important for both photic entrainment and determination of the free-running period.  (+info)

Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo. (6/96)

BACKGROUND: Decreased heart rate variability (HRV) and increased blood pressure variability (BPV), determined in part by nitric oxide (NO)-dependent endothelial dysfunction, are correlated with adverse prognosis in cardiovascular diseases. We examined potential alterations in BPV and HRV in genetically dyslipidemic, apolipoprotein (apo) E-/-, and control mice and the effect of chronic statin treatment on these parameters in relation to their NO synthase (NOS)-modifying properties. METHODS AND RESULTS: BP and HR were recorded in unrestrained, nonanesthetized mice with implanted telemetry devices with or without rosuvastatin. Cardiac and aortic expression of endothelial NOS and caveolin-1 were measured by immunoblotting. Both systolic BP and HR were elevated in apoE-/- mice, with abolition of their circadian cycles. Spectral analysis showed an increase in their systolic BPV in the very-low-frequency (+17%) band and a decrease in HRV in the high-frequency (-57%) band, reflecting neurohumoral and autonomic dysfunction. Decreased sensitivity to acute injection of atropine or an NOS inhibitor indicated basal alterations in both parasympathetic and NOS regulatory systems in apoE-/- mice. Aortic caveolin-1 protein, an inhibitor of endothelial NOS, was also increased in these mice by 2.0-fold and correlated positively with systolic BPV in the very-low-frequency band. Rosuvastatin treatment corrected the hemodynamic and caveolin-1 expression changes despite persisting elevated plasma cholesterol levels. CONCLUSIONS: Rosuvastatin decreases caveolin-1 expression and promotes NOS function in apoE-/-, dyslipidemic mice in vivo, with concurrent improvements in BPV and HRV. This highlights the beneficial effects of rosuvastatin on cardiovascular function beyond those attributed to lipid lowering.  (+info)

An abrupt shift in the day/night cycle causes desynchrony in the mammalian circadian center. (7/96)

The suprachiasmatic nucleus (SCN) is the neuroanatomical locus of the mammalian circadian pacemaker. Here we demonstrate that an abrupt shift in the light/dark (LD) cycle disrupts the synchronous oscillation of circadian components in the rat SCN. The phases of the RNA cycles of the period genes Per1 and Per2 and the cryptochrome gene Cry1 shifted rapidly in the ventrolateral, photoreceptive region of the SCN, but were relatively slow to shift in the dorsomedial region. During the period of desynchrony, the animals displayed increased nighttime rest, the timing of which was inversely correlated with the expression of Per1 mRNA in the dorsomedial SCN. Molecular resynchrony required approximately 6 d after a 10 hr delay and 9 approximately 13 d after a 6 hr advance of the LD cycle and was accompanied by the reemergence of normal rest-activity patterns. This dissociation and slow resynchronization of endogenous oscillators within the SCN after an LD cycle shift suggests a mechanism for the physiological symptoms that constitute jet lag.  (+info)

Loss of circadian rhythm of blood pressure following acute stroke. (8/96)

BACKGROUND: Epidemiology of acute stroke in developing countries differs from that in the developed world, for example, the age at stroke, risk factors, subtypes of stroke and prognosis. Hypertension remains a dominant risk factor and prognostic indicator in patients with stroke in all communities. The risk of stroke is directly related to elevations of blood pressure. A number of clinical studies have shown that the control of hypertension leads to a reduction in the incidence of stroke in a community. However there is still considerable controversy surrounds the changes in blood pressure in various subtypes of strokes and problem of management of elevated BP after stroke. We studied the circadian rhythm of blood pressure in patients following acute stroke. METHODS: To study the circadian rhythm of blood pressure, fifty consecutive patients with an acute stroke who were admitted to medical emergency within 120 hours of onset were included in the study. After a detailed history and clinical examination, a continuous blood pressure monitor (Spacelab 90207) was attached on the side ipsilateral to intracranial lesion (unaffected arm). The blood pressure was recorded for 24 hours at 15 minutes interval during daytime (6.00 am-6.00 pm) and 20 minutes interval overnight (6 pm to 6 am). RESULTS: Risk factors for stroke in 50 patients included hypertension in 31(62%), diabetes mellitus in 4 (8%), smoking in 13 (26%) and previous history of transient ischemic attack in 7 (14%) patients. Mean systolic pressure and diastolic pressure at admission were higher in patients with hemorrhagic stroke -29 patients (177 +/- 24 mmHg and 105 +/- 19 mmHg respectively) compared to patients with ischemic strokes-21 patients (150 +/- 36 mm Hg and 89 +/- 18 mm Hg respectively, p value <0.01 in both comparisons). The normal diurnal variation in blood pressure (night time dipping of more than 10%) was abolished in 44 (88%) of patients. Out of 44 nondippers, 29 patients showed reverse dipping i.e. rise of BP during night time compared to day time levels. None of the risk factors, clinical or laboratory variables, type of stroke or blood pressure changes differed significantly between these two groups. CONCLUSIONS: Therefore, we showed a pathologically reduced or abolished circadian BP variation after stroke. Absence of normal dipping results in a higher 24 hour blood pressure load and may have more target organ damage than those with normal diurnal variation of blood pressure.  (+info)

Long durations of rotating nightshift work may contribute to risk of hip and wrist fractures, although the potential for unexplained confounding cannot be ruled out.
Within the Life Safety Code, the NFPAs requirements for emergency lighting are referenced under section 7.9. Emergency illumination (when required) must be provided for a minimum of 1.5-hours in the event of failure of normal lighting. The emergency lighting must be arranged to provide initial illumination of not less than an average of one foot-candle and a minimum at any point of 0.1-foot-candle measured along the path of egress at floor level. And the emergency lighting system must be arranged to provide illumination automatically in the event of any interruption of normal lighting (section 7.9.2.3). ...
Although sleep and circadian rhythm disturbances are significant features of bipolar disorder and are associated with illness severity and recurrence, less is known about their significance prior to illness onset. Therefore, this study investigated these variables using objective assessment methods within a sample at high-risk of bipolar spectrum disorders. Thirty-one high-risk and 24 age- and gender-matched control participants wore an actigraph for 7 days to obtain sleep and circadian activity data. Self-report measures of mood, bed and get-up times, and cognitive style were also obtained. High-risk participants exhibited greater variability in duration, fragmentation, and efficiency of sleep, shorter sleep duration, and later and more variable bedtimes than controls. They also had lower relative amplitude of activity patterns and made more positive self-appraisals for hypomanic experiences. Logistic regression showed that positive self-appraisal and variability in bedtime significantly ...
Non-24-Hour sleep-wake syndrome (free-running type or non-24-hour circadian rhythm disorder) is a rare disorder. Learn more about diagnosis & treatment.
To examine the effects of this disruption of circadian rhythm in mammals, the researchers exposed healthy mice to 20-h light/dark cycles, incongruous with their endogenous ∼24-h circadian period.. Over time, this disruption of circadian rhythm resulted in accelerated weight gain and obesity, as well as changes in metabolic hormones.. In addition, the researchers found marked in changes in the brains of these animals including loss of dendritic length and decreased complexity of neurons in brain regions important for complex executive functions and emotional control.. Consistent with these changes in brain architecture, disrupted animals showed decreased cognitive flexibility and changes in emotionality in experiments designed to test these functions.. These findings certainly support the notion that chronically disrupting the natural (24-h) circadian rhythm in mammals can lead to substantial changes in behaviour and alterations in metabolism that would promote weight gain.. Certainly further ...
Principal Investigator:UCHIYAMA Makoto, Project Period (FY):1996 - 1997, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Psychiatric science
Muming Poo, director of the Institute of Neuroscience of Chinese Academy of Sciences, introduces the significance of the cloned monkey models with circadian rhythm disorders at a press conference in Shanghai, east China, Jan. 23, 2019. China has cloned five monkeys from a gene-edited macaque with circadian rhythm disorders, the first time multiple monkeys have been cloned from a gene-edited monkey for biomedical research. Scientists made the announcement Thursday, with two articles published in National Science Review, a top Chinese journal in English. The cloned monkeys were born in Shanghai at Institute of Neuroscience of Chinese Academy of Sciences. (Xinhua/Jin Liwang). ...
Kirsten ten Tusscher first of all made a model that described the electrical behaviour of individual human heart muscle cells. She demonstrated that the behaviour of this model corresponded well with results from experiments on human heart cells. The source code of this cell model is freely available on Internet.. The researcher then used her new model to simulate the behaviour of 13,5 million individual grid points, which together form the anatomy of a human heart. As the model is extremely large and requires a considerable amount of calculating power, she used the TERAS supercomputer of SARA Computing and Networking Services and a mini-Beowulf cluster in her own Department of Theoretical Biology at Utrecht University. With this she studied the behaviour of electrical wave patterns during certain rhythm disorders in the human heart.. Heart rhythm disorders are abnormalities in the timing, sequence and co-ordination of how the heart muscle contracts. These vary in seriousness from palpitations ...
Clinical Presentation. The clinical presentation varies between patients and conditions, ranging from no symptoms to severe and frequently occurring symptoms 10. Though palpitations may occur infrequently, the typical symptoms are syncope (fainting) and cardiac arrest. Most inherited heart rhythm disorders are caused by autosomal dominant mutations 11-13. This means that a single genetic defect is present that results in the clinical condition that is inherited or transmitted to 50% of offspring. Typically, an index case (termed proband) presents with fainting, cardiac arrest or sudden death, and family screening identifies other members that are affected but with little or no symptoms. Being genetically affected, however, does not necessarily mean that individuals will be symptomatic. Penetrance is the term used to describe the proportion of individuals who possess the genetic mutation and are also symptomatic. The penetrance of inherited heart rhythm disorders is variable, ranging from 20-60% ...
How to Treat Heart Rhythm Disorders with Exercise. If you find out that you have a heart rhythm disorder, also known as an arrhythmia, it does not mean that you can never exercise again.http://www.heart.org/HEARTORG/Conditions/Arrhythmia...
There are eight reversible factors that can cause depression.. For some, depression may result from a combination of genetics, circadian rhythm disturbances, upbringing and social factors.. For others, depression may be rooted in a lack of dietary omega-3 fats combined with harmful addictions and adverse frontal lobe factors.. Exercise, herbs and nutrition play a role in the brains ability to manufacture serotonin and other neurotransmitters; thus, one may be able to manage good and bad stress, improve mood and change ones attitude and actions.. Dr. Neil Nedley, internal medicine specialist in cardiology, gastroenterology, and mental health and lifestyle medicine, has put together a DVD and eight-week depression recovery program.. This is being offered to Campbell River as a community service by Family Health and Education.. There are two free introductory sessions at 7 p.m. on Tues. Oct. 4 and Tues. Oct. 11. The eight-week program happens every Tuesday from 7-9 p.m. from Oct. 18 --Dec. 6, ...
The open and flexible UltraGATEWAY allows NightShift to build the routing and configuration of the data directly into their reporting and administration system. This makes it seamless to administer a scalable and growing radiology network, allowing simple modification and additions of doctors, customer sites and data centers in a constantly demanding environment. This partnership helps UltraRAD provide a better workflow driven solution for its customers and build a solid infrastructure for Nightshift ...
VELscope System uses blue spectrum lighting to screen for oral cancer. The VELscope® Oral Assessment System centers on a handheld scope that we use to screen for oral tissue abnormalities, including cancer. Unlike other adjunctive devices used for oral screening, the VELscope® does not require any dyes or prolonged testing procedures. In fact, a VELscope® exam is performed in our office during a routine hygiene exam (and under normal lighting conditions) in about two minutes. VELscope® technology is changing the way oral cancer screenings take place. The VELscope® handheld device emits a harmless, bright blue light which is used to inspect the mouth and tongue. The device is extremely sensitive to abnormal tissue changes and the distinctive blue-spectrum light causes the soft tissues of the mouth to naturally fluoresce. Healthy tissues fluoresce in distinct patterns that are visibly disrupted by trauma or disease, such as neoplastic lesions, and fungal, viral or bacterial infections. We use ...
The usefulness of QLF™ for the normal clinical practice lies, for some people, primarily in the realm of prevention and patient communication. Below an example of the use of QLF™ for the detection of cracks that are pretty hard, if not impossible, to detect with the naked eye under normal lighting conditions. See the QLF Library under Cracks. ...
iltered, temperature-controlled units with a 12 h light/dark cycle with free access to food and water. Animals were monitored for signs of distress 9128839
Christmas is coming, the goose is getting fat . . .but 1.4 million NHS staff are heading off to work. In this perfect present for anyone who has ever set foot in a hospital, Adam Kay delves back into his diaries for a hilarious, horrifying and sometimes heartbreaking peek behind the blue curtain at Christmastime. Twas the Nightshift Before Christmas is a love letter to all those who spend their festive season on the front line, removing babies and baubles from the various places they get stuck, at the most wonderful time of the year.
Save when you order Mucinex Nightshift Sinus Relief Liquid and thousands of other foods from GIANT online. Fast delivery to your home or office. Save money on your first order. Try our grocery delivery service today!
Healthy people with Aβ buildup have irregular circadian rhythms. In mice, circadian disruptions dull daily Aβ oscillations and lead to more plaques.. ...
Healthy people with Aβ buildup have irregular circadian rhythms. In mice, circadian disruptions dull daily Aβ oscillations and lead to more plaques.. ...
When the human brain takes on intellectually challenging tasks, groups of neurons tune in to one another for a fraction of a second and harmonise, then go back to improvising, says a new study.
The underlying cause of any heart rhythm disorder provides the basis for selecting the best treatment plan. In general, the best treatment is the least invasive option that effectively controls the heart rhythm disorder. Treatment options fall into several categories from the least to the most invasive.
A method for quantifying cardiac desynchrony of the right and left ventricles includes obtaining cardiac acquisition data from a medical imaging system, and determining a movement profile from the cardiac acquisition data. The movement profile is directed toward identifying at least one of a time-based contraction parameter for a region of the left ventricle (LV), and a displacement-based contraction parameter for a region of the LV. The determined movement profile is visually displayed by generating a 3D model therefrom.
Buy Cordarone Online! Cordarone is used to treat a variety of different types of fast, abnormal heart rhythms (these are known as tachyarrhythmias). It is used for severe rhythm disorders when other treatments are not effective or cannot be used.
Buy Cordarone Online! Cordarone is used to treat a variety of different types of fast, abnormal heart rhythms (these are known as tachyarrhythmias). It is used for severe rhythm disorders when other treatments are not effective or cannot be used.
The human body functions according to a circadian rhythm thought to be controlled by a biological clock located in the part of the brain called the hypothalamus. There are several distinct disorders of our circadian rhythm and these are listed below: ...
The University Health Network (UHN) is excited to be hosting the 2018 Traumatic Brain Injury Conference an annual, one day event for healthcare practitioners, students, researchers, and community members who encounter traumatic brain injury in their practice. This event will explore topics such as concussion, long-term effects of brain injury, rehabilitation, and sleep/wake disturbances following brain injury from prominent researchers and renowned scholars.. February 2, 2018 ...
The University Health Network (UHN) is excited to be hosting the 2018 Traumatic Brain Injury Conference an annual, one day event for healthcare practitioners, students, researchers, and community members who encounter traumatic brain injury in their practice. This event will explore topics such as concussion, long-term effects of brain injury, rehabilitation, and sleep/wake disturbances following brain injury from prominent researchers and renowned scholars.. February 2, 2018 ...
TY - JOUR. T1 - An ancestral haplotype of the human PERIOD2 gene associates with reduced sensitivity to light-induced melatonin suppression. AU - Akiyama, Tokiho. AU - Katsumura, Takafumi. AU - Nakagome, Shigeki. AU - Lee, Sang Il. AU - Joh, Keiichiro. AU - Soejima, Hidenobu. AU - Fujimoto, Kazuma. AU - Kimura, Ryosuke. AU - Ishida, Hajime. AU - Hanihara, Tsunehiko. AU - Yasukouchi, Akira. AU - Satta, Yoko. AU - Higuchi, Shigekazu. AU - Oota, Hiroki. PY - 2017/6. Y1 - 2017/6. N2 - Humans show various responses to the environmental stimulus in individual levels as physiological variations. However, it has been unclear if these are caused by genetic variations. In this study, we examined the association between the physiological variation of response to light-stimulus and genetic polymorphisms. We collected physiological data from 43 subjects, including light-induced melatonin suppression, and performed haplotype analyses on the clock genes, PER2 and PER3, exhibiting geographical differentiation ...
Bright light therapy Effects of bright light on cognitive and sleep-wake (circadian) rhythm disturbances in Alzheimer-type dementia Psychiatry Clin Neurosci 2000, 54, 352-3 Effects of phototherapy in patients with delayed sleep phase syndrome * Psychiatry Clin Neurosci 1999 Apr;53(2):231-3 Melatonin suppression by illumination of upper and lower visual fields * J Biol Rhythms. 1999 Apr;14(2):122-5…
Darsaud A, Bourdon L, Mercier S, Chapotot F, Bouteille B, Cespuglio R, Buguet A. Twenty-four-hour disruption of the sleep-wake cycle and sleep-onset REM-like episodes in a rat model of African trypanosomiasis. Sleep. 2004 Feb 01; 27(1):42-6 ...
history or DSISD (Duke Insomnia Sleep Diagnostics) suggests sleep disorder other than insomnia (e.g., sleep apnea, narcolepsy, periodic leg movements, etc.), or have insomnia associated with circadian rhythm disturbances, such as night or rotating shift work or travel across more than four time zones in the 14 days before Initial Screening (Visit 1) or during the study ...
Statement of Need Recent catastrophic bus and train accidents in the Bronx, New York, have highlighted the importance of understanding the negative effects of circadian sleep-wake disruption in shift workers, especially those in positions of responsibility for public safety, including bus and train operators and healthcare workers. Scientific evidence exists that manipulations by employers and employees can reduce the risk of errors due to sleep deprivation, so long as there is an understanding of underlying chronobiologic principles and the corresponding therapeutic options that can reduce and improve circadian disruption.. Activity Goal This program is designed to present the current understanding of chronobiology and the effects upon health and disease and to highlight the importance of circadian disruption on shift workers performances and productivity. Appropriate interventions can be undertaken by employers and employees to mitigate the effects of circadian disruption by manipulating ...
Introduction: Shift work, characterized by irregular schedules resulting in sleep loss and misalignment of circadian rhythms, is associated with increased incidence of cardiovascular disease. We tested whether circadian misalignment has an adverse impact on cardiovascular function independently of sleep loss. Methods: 19 healthy adults were studied using a parallel group design comparing two inter
Sleep duration and disruption have a significant impact on human health, quality of life, and life expectancy. Among humans, it is clear that the biological need for sleep varies dramatically. Natural short sleepers have a lifelong tendency to sleep only 4-5 h per night and to awaken refreshed and energetic. Natural long sleepers biologically require 9-10 h/night to feel well rested. The reason for these physiological differences is unknown and the genetic basis has not been explored.. Although relatively little is known regarding the genetic basis of sleep, there is a wealth of information on the genetics of circadian clock function across species. Sleep and circadian function are distinct processes that interact in living organisms. Although these two systems can operate independently, recent studies indicate a more intimate relationship.. Over the last decade, genetic material has been collected from individuals and families with circadian rhythm disturbances including familial advanced sleep ...
WASHINGTON - According to a new survey issued by the Heart Rhythm Society, the majority of Americans are unaware of two serious and potentially life-threatening heart rhythm disorders, atrial fibrillation (AF) and sudden cardiac arrest (SCA). In fact, only one in three Americans have ever heard of AF or recognize the number of lives claimed each year from SCA. Throughout February, Heart Health Month, the Heart Rhythm Society spotlights the need for public education on heart rhythm disorders affecting millions of people, and the specialists best suited to treat them - electrophysiologists.. More than 250,000 deaths occur each year as a result of SCA, more than breast cancer, lung cancer or AIDs. Yet, according to the recent survey, more than 65 percent of Americans not only underestimate the seriousness of SCA, but also believe SCA is a type of heart attack. While this current data does show a 5 percent increase since the Societys 2008 SCA awareness survey, the lack of awareness remains high and ...
Circadian clocks are found in nearly all organisms, from bacteria to mammals, and ensure that behavioral and physiological processes occur at optimal times of day and in the correct temporal order. It is becoming increasingly clear that chronic circadian misalignment (CCM), such as occurs in shift workers or as a result of aberrant sleeping and eating schedules common to modern society, has profound metabolic and cognitive consequences, but the proximate mechanisms connecting CCM with reduced organismal health are unknown. Furthermore, it has been difficult to disentangle whether the health effects are directly induced by misalignment or are secondary to the alterations in sleep and activity levels that commonly occur with CCM. Here, we investigated the consequences of CCM in the powerful model system of the fruit fly, Drosophila melanogaster. We subjected flies to daily 4-h phase delays in the light-dark schedule and used the Drosophila Activity Monitoring (DAM) system to continuously track locomotor
Behavioural signs and symptoms in dementia are of central clinical significance. There are a number of standardised rating scales available for the assessment of motor phenomena in dementia. However, there is no objective method of assessing these symptoms. In addition, the reliability of these scales, especially when used by caregivers from within families, has been questioned. In order to overcome this flaw, we propose the use of an actometric device for assessing behaviour motor symptoms in dementia. In the first part of this dissertation we assessed the reliability and the concurrent validity of an actometric device against two behavioural scales. Results show satisfactory validity and good reliability of this method. In the second part of this dissertation, we reanalysed data from our validation study, investigating whether the pattern of circadian rhythm disturbances is different in patients suffering from Alzheimer disease and patients suffering from vascular dementia, controlling ...
pH variation in Thionin: The Two-Faced Solution Integrated-Science students Erin Smyers and Nicole Loughner from Homer-Center High School in Homer City, PA, worked with their science team leader, Mark Shopland, to investigate the pH changes in an oxidation-reduction reaction. The students chose to work with Thionin based on the demonstration Thionin - The Two-Faced Solution published by Flinn Scientific Inc. (Publication No. 0815.00). According to the Flinn Chem-Fax, Thionin is an organic compound that in the oxidized form is purple and in the reduced form is colorless. When a reducing agent such as iron(II) ion (Fe2+) is added to an acidic thionin solution, the thionin (Thio+) molecule accepts two hydrogen atoms and is reduced to its colorless form. This reaction only takes place in the presence of an intense light source. Thio+ + 2Fe2+ + 2H+ + Light ↔ ThioH2+ + 2Fe3+ [purple] [colorless] The graph shows the relatively constant pH under normal lighting conditions and the varying pH levels of the
The following information is not official in terms of general campaign usage. It is copied from the Pathfinder Society Organized Play FAQ section because we thought it might be helpful information for a player or GM in adjudicating common problems or questions. Usage is up to the GM of your game.. What does a deaf PC (or other creature) need to do in order to read lips?. Any PC may learn to read lips with a rank in Linguistics as if they had learned a new language. When reading the lips of a speaking creature within 10 feet in normal lighting conditions, the reader need not make any skill checks. In situations of dim lighting, extreme distances, or to read the lips of someone trying to hide their words from the reader, the reader must make Perception checks (DC determined by the GM based on the situation). A lip reader may only understand spoken words in a language it knows.. [Source]. ...
Medications can be effective in treating Arrhythmias (Heart Rhythm Disturbances). Understand drugs and medical procedures for Arrhythmias (Heart Rhythm Disturbances), see research evidence, and discover other smart treatments for Arrhythmias (Heart Rhythm Disturbances) at FoundHealth.
Causes of Arrhythmias (Heart Rhythm Disturbances) can depend on each individual situation. Learn about causes of Arrhythmias (Heart Rhythm Disturbances) and find symptoms, diagnosis, and many types of smart treatments for Arrhythmias (Heart Rhythm Disturbances) at FoundHealth.
FECYT - Spanish Foundation for Science and Technology. A possible pharmacology objective for chemotherapy. Patients receiving chemical treatment for cancer often suffer fatigue and body weight loss, two of the most worrying effects of this therapy linked to the alteration of their circadian rhythms.. The circadian system, better known as our biological clock, is responsible for coordinating all the processes that take place in our organism.. If it does not function correctly, what is known as a circadian disruption or chronodisruption, has for years been linked to an increased incidence of cancer, obesity, diabetes, depression, cognitive problems or cardiovascular diseases.. Also, circadian disruption in cancer patients aggravates the prognosis of the disease and the chance of survival for these patients diminishes, Elisabet Ortiz Tudela, a researcher at the University of Murcia, told SINC.. The expert is the author of a study published in the International Journal of Cancer, which reveals ...
Heart rhythm disorders or heart rhythm disorders heart rhythm is irregular, sometimes fast (tachycardia) or slow or irregular (arrhythmia). At the heart rhythm disorder symptoms are generally mild without symptoms, so interference can only be known if you are feeling the pulse of the chest or the baby and found the irregular rhythm until hard to count how many times per minute her.. If this is the case does not mean there is no problem, precisely you should take him to the doctor to check and make sure his condition. As a precaution, you could be asked for recording an electrocardiogram (ECG) is used to determine the condition of his heart.. From the ECG recording, you can find out the childs heart condition in a normal state or there is interference. In severe heart rhythm disorders, the symptoms are a decrease in blood pressure, resulting in a pale, cold sweat and the body feels cold. Worse could seizures unconscious.. ...
Abstract:. BACKGROUND: Sleep-wake disturbances have frequently been reported in bipolar disorder and schizophrenia, and are considered to be caused by an underlying circadian rhythm disorder. The study presented here was designed to investigate the existence of Per3 polymorphism in bipolar disorder type I (BD-I) and schizophrenic patients in South India. METHODS: Blood samples were collected from 311 BD-I patients, 293 schizophrenia patients, and 346 age- and sex-matched normal controls. Per3 genotyping was performed on DNA by polymerase chain reaction using specific primers. RESULTS: An increased prevalence of five repeat homozygotes was seen in BD-I patients as compared with healthy controls (odds ratio =1.72 [95% confidence interval: 1.08-2.76, P=0.02]). In BD-I patients, the frequency of the five repeat allele was higher (allele frequency =0.41), and that of the four repeat allele lower (allele frequency =0.36) (χ (2)=4.634; P,0.03) than in the control group. No significant association was ...
obesity and mental illness. However, circadian disruptions are becoming increasingly widespread in our modern world. As such, there is an urgent need for novel technological solutions to address these issues.. In this talk, I will introduce the notion of Circadian Computing - technologies that support our innate biological rhythms. Specifically, I will describe a number of my recent projects in this area. First, I will present novel sensing and data-driven methods that can be used to assess sleep and related circadian disruptions. Next, I will explain how we can model and predict alertness, a key circadian process for cognitive performance. Third, I will describe a smartphone based tool for maintaining circadian stability in patients with bipolar disorder. To conclude, I will discuss a vision for how Circadian Computing can radically transform healthcare, including by augmenting performance, enabling preemptive care for mental health patients, and complementing current precision medicine ...
Sleep refreshes and restores us. However, when sleep is disrupted it can result in behavioral as well as physical problems that can seriously impact the ability of a child to perform optimally in school. This talk will provide participants with an overview of sleep and the problems that are associated with it. The highlights will include a number of the more common disturbances of sleep such as bedtime difficulties, night waking, circadian rhythm disorders and sleep terrors, and recent work on the nonmedical treatments for these problems. Described will be our work with children who have autism spectrum disorder who pose unique challenges and who exhibit a higher prevalence of sleep problems compared to the general population.. Review V. Mark Durands biographical statement.. ...
Generation of Knockout Mice. The methods for generation of the knockout mice were as described in detail by Roberts et al. (2000). In brief, gene inactivation was obtained by disruption of the first coding exon of the μ-opioid receptor gene in 129/SV embryonic stem cells. Germline transmission occurred from the breeding of chimeric males with C57BL/6Orl females. After mice were genotyped, those showing germline transmission were used as founder animals to produce the F1 animals used in these experiments. We used male homozygous MOR KO and WT littermate mice (shipped from Scripps Research Institute, La Jolla, CA) in these experiments. The genetic background of these mice was a hybrid C57BL/6Orl × 129/SV strain. We housed mice one to three per cage in a temperature-controlled room in which the lights were on a 12-h light/dark cycle with lights off at 10:00 AM.. In Vitro Single-Cell Recordings. We used 4- to 5-month-old MOR KO and genetically intact WT littermate mice in this study. In some ...
Background Maternal alcohol consumption is known to adversely affect fetal neurodevelopment. Cages and bedding, including access to environmental enrichment, were standardized between cages. Colonies were kept inside a controlled environment on a 14/10-h light/dark cycle at a heat of 21C to 24C with 40% to 60% moisture. Female mice of approximately 8 weeks of age were time-mated immediately with 8- to 12-week aged males. During gestation, dams were housed separately in standard cages. Six treatment occasions were selected to approximate ethanol publicity occurring in MK-0974 manufacture the human being 1st, second, and third trimesters: dam treatment at embryonic days (E) 8 and 11 (human being trimester one equivalent), E14 and 16 MK-0974 manufacture (human being second trimester equivalent), and pup treatment on postnatal days (P) 4 and 7 (human being third trimester equivalent) [19,25]. Each mouse (dam or pup) was treated on two treatment. To model punctuated high-blood alcohol (binge-like) ...
Induction of Diabetes. All procedures used in this study were approved by the animal care and use committee at Southern Illinois University, School of Medicine, and conformed according to National Institutes of Health and institutional guidelines. Mice were housed in standard cages and maintained on a 12-h light/dark cycle at an ambient temperature of 22 ± 1°C. Mice were housed in specific pathogen-free barrier animal facility, and rodent laboratory chow (Laboratory Diet 5001; Nutrition International, Inc., Brentwood, MO) and drinking water were provided ad libitum. Mice were at least 6 to 10 weeks of age and weighed between 18 and 23 g at the beginning of the experiments.. Age-matched single transgenic mice (Ins-HA.D2 mice), which express influenza hemagglutinin (HA) peptide, were used and were kindly provided by Dr. Lo (Lo et al., 1992). Freshly prepared STZ (50-200 mg/kg) in saline (pH 4.5 with 0.1 N citrate buffer) was injected intraperitoneally as described previously (Kamei et al., ...
Subjects. Male Tg2576 mice (Hsiao et al., 1996), expressing a double mutation (K670N/M671L) of human APP, were obtained from Taconic (Germantown, NY) and used for subsequent breeding. Transgenic mice heterozygous for the K670N/M671L transgene were maintained on a hybrid C57BL/6/SJL background through breeding hemizygous males with B6SJLF1 females. Genotypes were confirmed by PCR, and animals homozygous for the retinal degeneration mutation were excluded. Individually housed mice, maintained on a 12 h light/dark cycle, had ad libitum access to food and water. Studies were performed comparing heterozygous transgenic (Tg2576) males to age-matched transgene-negative littermates (controls).. β-Amyloid levels. Male Tg2576 mice (20 weeks of age) were given vehicle or 100 mg/kg DAPT orally. Brains from saline-perfused mice (DAPT-treated mice killed 0.5-24 h and vehicle-treated 4 h after dosing) were homogenized in 10:1 (v/w) cold 5 m guanidine, 50 mm Tris-HCl, shaken at room temperature 3 h, then ...
vivarium on a 12 h light/dark cycle with food and water provided ad libitum. Heat-map visualization was performed using the heatmap.2 package. Li M, Stowell C, Xiong ZG, Saugstad J, Simon RP, Geromanos S, Langridge J, Lan JQ, [PubMed]; Stevens SL, Ciesielski TM, Marsh BJ, Yang T, Homen DS, Boule JL, Ask PriceView More ...
Materials. Diclofenac sodium, CBZ, reserpine, and β-D-glucuronide glucuronosohydrolase (β-glucuronidase, EC 3.2.1.31) were purchased from Sigma-Aldrich (St. Louis, MO). D-SG, D-SNAC, 1-(2,6-dichlorophenyl)indolin-2-one, and D-1-O-G were synthesized as described below. All solvents used for HPLC and LC/MS were of chromatographic grade. Stock solutions of diclofenac (10 mM), D-SG (10 mM), D-1-O-G (1.3 mM), and D-SNAC (10 mM) were prepared as solutions in 50:50 acetonitrile/water (3% formic acid).. Animal Treatment. Male Sprague-Dawley rats (N = 2; 250 -275 g) were purchased from Charles River Breeding Laboratories (Portage, MI). Upon arrival, animals were acclimated following a 12-h light/dark cycle in a humidity- and temperature-controlled environment for 2 weeks in accordance with the National Institutes of Health publication Guide for the Care and Use of Laboratory Animals. After the first week of acclimation, surgically implanted venous and biliary catheters were placed into the superior ...
Tarfa M. P.*, Mshelia P. P., Mahdi O. and Leonard, M. P.. ABSTRACT. Randomly bred normal Forty (40) male albino rats of wistar strain obtained from the wistar rat colony of the Department of Pharmacology, University of Jos, were used for this study. All the animals weighing between 90 - 230 grams and 10 - 20 weeks old were maintained under uniform conditions across ventilated room (temperature 25 - 28oc, and 12h light/dark cycle), with free access to standard diet of Growers Mash (Vital Feed Nig PLC, Maiduguri) and portable water ad Libitum. The rats were divided into groups I, II, III and IV with 10 rats each. However, the rats in groups II, III and IV received oral administration of the solution of Methylene Chloride at 420mg/kg, 840mg/kg and 1260mg/kg respectively for 5 weeks via oro-gastric intubation. Routine histological sections of the testes obtained from rats treated with methylene chloride at all the dose levels (420mg/kg, 840mg/kg and 1260mg/kg) for 5 weeks were characterized by ...
Learn more about Type of Arrhythmias (Heart Rhythm Disturbances) at Coliseum Health System Main Page Types of Arrhythmias Cause ...
Learn more about Surgical Procedures for Arrhythmias (Heart Rhythm Disturbances) at Memorial Hospital Main Page Types of Arrhythmias ...
Learn more about Conditions InDepth: Arrhythmias (Heart Rhythm Disturbances) at St. Davids HealthCare Main Page Types of Arrhythmias ...
Learn more about Talking to Your Doctor About Arrhythmias (Heart Rhythm Disturbances) at Doctors Hospital of Augusta Main Page Types...
Learn more about Conditions InDepth: Arrhythmias (Heart Rhythm Disturbances) at Portsmouth Regional Hospital Main Page Types of Arrhythmias ...
Learn more about Treatments for Arrhythmias (Heart Rhythm Disturbances) at Doctors Hospital of Augusta Main Page Types of Arrhythmias ...
Learn more about Type of Arrhythmias (Heart Rhythm Disturbances) at Portsmouth Regional Hospital Main Page Types of Arrhythmias Cause ...
The U.S. Food and Drug Administration today approved the first pacemaker that does not require the use of wired leads to provide an electrical connection between the pulse-generating device and the heart. While the Micra Transcatheter Pacing System works like other pacemakers to regulate heart rate, the self-contained, inch-long device is implanted directly in the right ventricle chamber of the heart.
Drinking small amounts of alcohol frequently is linked with a higher likelihood of atrial fibrillation than binge drinking, according to research published today in EP Europace, a journal of the European Society of Cardiology (ESC).
The Council on Cardiac Pacing and Electrophysiology endeavors to provide continuing medical education for cardiologists and non-cardiologists on cardiac rhythm disorders, particularly on diagnosis, risk stratification and advances in management, the ultimate goal of which is to enhance the ability of non-electrophysiologists to care for and treat patients with cardiac rhythm disorders.. Chair 2014=2017: Erdie C. Fedriguilan, MD. Immediate Past Chair 2011-2014: Gladys Ruth S. David, ...
Munster head coach Anthony Foley died due to a heart condition which led to a build-up of fluid in his lungs, a French coroner has said.
There are many different types of heart rhythm disorders, each requiring different treatment. Usually, it is not necessary to treat occasional extra heartbeats (so-called extra systole). Rhythm disorders like bradycardia (a heartbeat which is too slow) or tachycardia (a heartbeat which is too fas
Circadian disruption has been implicated in tumour development, but the underlying mechanism remains unclear. Here, we show that the molecular clockwork within malignant human pancreatic epithelium is disrupted and that this disruption is mediated by miR-135b-induced BMAL1 repression. miR-135b directly targets the BMAL1 3-UTR and thereby disturbs the pancreatic oscillator, and the downregulation of miR-135b is essential for the realignment of the cellular clock. Asynchrony between miR-135b and BMAL1 expression impairs the local circadian gating control of tumour suppression and significantly promotes tumourigenesis and resistance to gemcitabine in pancreatic cancer (PC) cells, as demonstrated by bioinformatics analyses of public PC data sets and in vitro and in vivo functional studies ...
There were plenty of ooohs and ahhhs at Wellingtons Anzac dawn service today as Rawiri Phillips attended in a handmade soldier uniform his mum stayed up al
Our program offers comprehensive diagnosis and treatment of patients with heart rhythm disturbances and complex heart rhythm disorders
As part of a recent study, researchers tracked more than 10,000 middle-aged people for close to 14 years to understand the connection between microvascular disease and heart rhythm disorder.
Calaptin 40 mg (Verapamil) Calaptin 40 mg contains an active ingredient Verapamil.  It is an effective medicine used for the treatment of hypertension (High Blood Pressure), angina (chest pain) and heart rhythm disorders. Calaptin 40 mg general infor
Tiazac (diltiazem) is used to treat high blood pressure, angina and certain heart rhythm disorders. Includes Tiazac side effects, interactions and indications.
Cardizem is a calcium channel blocker which is used to treat high blood pressure, chest pain, and certain heart rhythm disorders.
Electrophysiology studies most often are recommended for patients with symptoms indicative of heart rhythm disorders or for people who may be at risk for sudden cardiac death.
Wirz-Justice, A. (2003). "Chronobiology and mood disorders". Dialogues in Clinical Neuroscience. 5 (4): 315-325. doi:10.31887/ ... Bipolar disorder is known to have a high heritability. Therefore, sleep disturbances in bipolar disorder could also have a ... Sleep is known to play an important role in the etiology and maintenance of bipolar disorder. Patients with bipolar disorder ... The diagnosis of a bipolar disorder is linked to various sleep disorders. Comorbidities include insomnia and hypersomnia. Other ...
Chronobiology Circadian rhythm sleep disorder Delayed sleep phase disorder Canavier CC (2006). "Phase response curve". ... light therapy is used as treatment for several affective disorders including seasonal affective disorder (SAD). In 2002 Brown ... Various sleep disorders and externals stresses (such as jet lag) can interfere with this. People with non-24-hour sleep-wake ... Lewy A, Sack R, Fredrickson R (1983). "The use of bright light in the treatment of chronobiologic sleep and mood disorders: The ...
"Bipolar disorder with seasonal pattern: clinical characteristics and gender influences". Chronobiology International. 30 (9): ... With seasonal pattern is a specifier for bipolar and related disorders, including bipolar I disorder and bipolar II disorder. ... Seasonal affective disorder (SAD) is a mood disorder subset, in which people who have normal mental health throughout most of ... Most people with SAD experience major depressive disorder, but as many as 20% may have a bipolar disorder. It is important to ...
... disrupted chronobiology/sleep, mood disorders/psychotropic medication use, and excessive alcohol use. The pathogenic role ... The syndrome is thought to be caused by an underlying disorder of energy utilization and storage. The cause of the syndrome is ... Reproductive disorders (such as polycystic ovary syndrome in women of reproductive age), and erectile dysfunction or decreased ... Lipodystrophic disorders in general are associated with metabolic syndrome. Both genetic (e.g., Berardinelli-Seip congenital ...
"The CLOCK gene and mood disorders: a case-control study and meta-analysis". Chronobiology International. 28 (9): 825-33. doi: ... Biology of bipolar disorder, Mood disorders, Causes of mental disorders, Biological psychiatry, Bipolar disorder). ... Bipolar disorder is an affective disorder characterized by periods of elevated and depressed mood. The cause and mechanism of ... Grunze, H. "Bipolar Disorder". In Zigmond, M; Rowland, L; Coyle, J (eds.). Neurobiology of Brain Disorder: Biological Basis of ...
... a circadian rhythm sleep disorder". Chronobiology International. 22 (3): 559-70. doi:10.1081/CBI-200062410. PMID 16076654. ... "Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, ... There have been cases of DSPD developing into non-24-hour sleep-wake disorder, a severe and debilitating disorder in which the ... It has been named as one of the sleep disorders most commonly misdiagnosed as a primary psychiatric disorder. DSPD is often ...
Johnson, Carl H. (2013). "Entrainment of Circadian Programs" (PDF). Chronobiology International. 20 (5): 741-774. doi:10.1081/ ... "Circadian Rhythm Sleep Disorders: Part II, Advanced Sleep Phase Disorder, Delayed Sleep Phase Disorder, Free-Running Disorder, ... Advanced Sleep Phase Disorder (ASPD), also known as the advanced sleep-phase type (ASPT) of circadian rhythm sleep disorder, is ... Delayed sleep phase disorder Irregular sleep-wake rhythm Non-24-hour sleep-wake disorder Dodson, Ehren R.; Zee, Phyllis C (2010 ...
Chronobiology Irregular sleep-wake rhythm Non-24-hour sleep-wake disorder Shift work sleep disorder Jet lag Madrid-Valero JJ, ... Some of these circadian disorders include Advanced Sleep Phase Disorder (ASPD) and Delayed Sleep Phase Disorder (DSPD). ... The disorder can manifest any time from age 18 to 60, but the average age of affected individuals is 50 years old. The disorder ... The disorder is caused by a mutation of the PRNP gene resulting in the creation of a prion. These prions result in ...
Chronobiology International. 19 (3): 649-658. doi:10.1081/CBI-120004546. PMID 12069043. S2CID 24038952. Rajaratnam, S. M. W., ... "Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, ... Circadian rhythm sleep disorder, the parent spectrum of sleep disorders including non-24-hour sleep-wake disorder. Delayed ... the disorder is also known as: non-24-hour sleep-wake syndrome or disorder, free-running disorder (FRD),[citation needed] ...
Circadian rhythm sleep disorder Chronobiology Sleep medicine (Articles with short description, Short description is different ... Sleep and sleep disorders: a neuropsychopharmacological approach. Georgetown, Tex., U.S.A: Landes Bioscience/Eurekah.com. ISBN ...
Chronobiology Circadian advantage Circadian clock Circadian oscillator Circadian rhythm disorders Electronic media and sleep ... Seasonal affective disorder creates a model in which decreased day length during autumn and winter increases depressive ... Reviews in Endocrine & Metabolic Disorders. 10 (4): 301-10. doi:10.1007/s11154-009-9121-9. PMID 19777352. S2CID 8653740. van ... and depressive symptoms in this disorder. Light seems to have therapeutic antidepressant effects when an organism is exposed to ...
ASPD and non-24-hour sleep-wake disorder are improperly entrained to light/dark. Crepuscular - Animals active at twilight (i.e ... In the study of chronobiology, entrainment occurs when rhythmic physiological or behavioral events match their period to that ... "Basic Science Review on Circadian Rhythm Biology and Circadian Sleep Disorders" (PDF). Annals Academy Med Singapore. 37 (8): ...
Advanced sleep phase syndrome Chronobiology Circadian rhythm Delayed sleep phase disorder "Irregular sleep-wake syndrome: ... "Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, ... Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder ( ... An overnight sleep study is usually not needed to detect this disorder, but may be indicated if other sleep disorders, such as ...
Amber-tinted lenses have been shown to affect the circadian rhythm and treat delayed sleep phase disorder. According to the US ... Chronobiology International. 33 (8): 1037-1044. doi:10.1080/07420528.2016.1194289. PMID 27322730. S2CID 35562927. Burkhart, ... "Wearing blue light-blocking glasses in the evening advances circadian rhythms in the patients with delayed sleep phase disorder ... Chronobiology International. 26 (8): 1602-1612. doi:10.3109/07420520903523719. PMID 20030543. S2CID 145296760. Becoming a ...
... such as Advanced sleep phase disorder Delayed sleep phase disorder Non-24-hour sleep-wake disorder Chronobiology CLOCK ... A number of other disorders, such as bipolar disorder and some sleep disorders such as delayed sleep phase disorder (DSPD), are ... Maung SC, El Sara A, Chapman C, Cohen D, Cukor D (May 2016). "Sleep disorders and chronic kidney disease". World Journal of ... In clinical settings, an abnormal circadian rhythm in humans is known as a circadian rhythm sleep disorder. While there are ...
... to reestablish the circadian rhythm and treat delayed sleep phase disorder. Some models have polarized lenses, made of Polaroid ... Chronobiology International. 33 (8): 1037-1044. doi:10.1080/07420528.2016.1194289. PMID 27322730. S2CID 35562927. Burkhart, ... "Wearing blue light-blocking glasses in the evening advances circadian rhythms in the patients with delayed sleep phase disorder ... Chronobiology International. 26 (8): 1602-1612. doi:10.3109/07420520903523719. PMID 20030543. S2CID 145296760. Fassel, Preston ...
Chronobiology Familial sleep traits Light effects on circadian rhythm Phase response curve Sleep diary Sleep medicine Dagan, ... Delayed sleep phase disorder, advanced sleep phase disorder, non-24-hour sleep-wake disorder and irregular sleep-wake rhythm ... Advanced Sleep Phase Disorder, Delayed Sleep Phase Disorder, Free-Running Disorder, and Irregular Sleep-Wake Rhythm. PDF, 18 ... Circadian rhythm sleep disorders (CRSD), also known as circadian rhythm sleep-wake disorders (CRSWD), are a family of sleep ...
Chronobiology Photosensitive ganglion cell Sense of time Retinohypothalamic tract Shift work sleep disorder Non-24-hour sleep- ... Reid KJ, Chang AM, Zee PC (May 2004). "Circadian rhythm sleep disorders". The Medical Clinics of North America. 88 (3): 631-51 ... wake disorder Fahey J (2009-10-15). "How Your Brain Tells Time". Out Of The Labs. Forbes. Clodong S, Dühring U, Kronk L, Wilde ... is reflected by several circadian rhythm sleep disorders, where this process does not function normally. Neurons in the ...
Bipolar disorder - Cardiopulmonary resuscitation - Calvin-Benson cycle - Cell cycle - Chronobiology - Citric acid cycle - ...
Circadian rhythm sleep disorder Horne, JA, Östberg O (1976). "A self-assessment questionnaire to determine morningness- ... Chronobiology International. 28 (3): 238-247. doi:10.3109/07420528.2010.549599. PMC 3818690. PMID 21452919. Hur YM, Bouchard TJ ... eveningness in human circadian rhythms". International Journal of Chronobiology. 4 (2): 97-110. PMID 1027738.{{cite journal}}: ...
Colony collapse disorder, bees Исчезновение тараканов на Белгородчине не связано с радиацией :: ИА Бел.Ру - Новости Белгорода ... Ozone holes may also lead to abnormal chronobiology in cockroaches. Internal competitions between cockroaches may decrease the ...
"International ChronoBiology Summer School in Florida from May 26-29, 2020 , SRBR: Society for Research on Biological Rhythms". ... She is currently the director at the Center for Sleep and Circadian Rhythm Disorders at Sapporo Hanazono Hospital and works as ... Sato Honma and Ken-ichi Honma had a chronobiology laboratory for over 30 years at Hokkaido University, and many of the students ... She was one of the instructors for the International Chronobiology Summer School, in Beijing in 2016, and that in Munich 2019. ...
Lamberg, Lynne (2000). Skin Disorders (21st Century Health and Wellness). New York: Chelsea House Publishing. ISBN 0791059839. ... Lamberg, Lynne (November 1, 2000). Bodyrhythms: Chronobiology and Peak Performance. ISBN 0595147852.{{cite book}}: CS1 maint: ... Lamberg, Lynne (1994). Bodyrhythms: Chronobiology and Peak Performance. William Morrow & Co. ISBN 0877959919. Cartwright, ... chronobiology, chronomedicine, chronotherapy and chronorecord-keeping. 'We pay more attention to watches we wear on our wrists ...
Some night owls with great difficulty adopting normal sleeping and waking times may have delayed sleep-phase disorder. Morning ... Chronobiology (2004) McCullough, David (1992). Truman. Simon & Schuster. p. 508. ISBN 978-0671456542. Sleep Discrimination ... Laura H. Smith/Charles H. Elliott, Seasonal Affective Disorder for Dummies (2007) p. 73 Maestripieri, Dario (2014-01-01). " ... the study of sleep cycles and other time-dependent biological systems Circadian rhythm sleep disorder Insomnia - the inability ...
... including Advanced sleep phase disorder Delayed sleep phase disorder Non-24-hour sleep-wake disorder Chronotherapy Sleep Sleep ... Meijer continues her study of circadian rhythms and chronobiology today as a Professor and Head of Neurophysiology Group at the ... Johanna Meijer (born 26 March 1959) is a Dutch scientist who has contributed significantly to the field of chronobiology. ... 1993: "Aschoff's Rule, a prize for eminent contributions in Chronobiology supporting the interdisciplinary spirit of the field ...
... anxiety disorder, and substance use disorder. Clock gene Period (gene) Cycle (gene) Timeless (gene) Chronobiology Oscillating ... deficit/hyperactivity disorder, major depressive disorder, bipolar disorder, ... Schuch JB, Genro JP, Bastos CR, Ghisleni G, Tovo-Rodrigues L (March 2018). "The role of CLOCK gene in psychiatric disorders: ... Mammalian mutations in the Clock gene have been found to result in autism spectrum disorder, schizophrenia, attention‐ ...
In: Trends in Chronobiology, ed. Hekkens W, Th JM, Jerkhof GA and Rhietveld WJ, Pergamon Press, Oxford and New York, pp. 149- ... His later work was more applicable to pathologies, such as psychiatric disorders and dangers of shift work schedules, which can ... Together with Erwin Bünning and Colin Pittendrigh, he is considered to be a co-founder of the field of chronobiology. Aschoff's ... Aschoff's work in the field of chronobiology introduced the idea that shifting one's light-dark cycle can result in harmful ...
Wehr and colleague Anna Wirz-Justice were awarded the Anna Monika Prize for their work in the chronobiology of depressive ... Wehr and colleague Norman E. Rosenthal are credited with identifying and describing Seasonal Affective Disorder (SAD) and ...
... is used as a medication in the treatment of sleep disorders such as insomnia and circadian rhythm sleep disorders ... Chronobiology International. 21 (1): 1-25. doi:10.1081/CBI-120027984. PMID 15129821. S2CID 42725506. Foster RG (June 2020). " ... like delayed sleep phase disorder, jet lag disorder, and shift work disorder. Besides melatonin, certain synthetic melatonin ... Riha RL (November 2018). "The use and misuse of exogenous melatonin in the treatment of sleep disorders". Curr Opin Pulm Med. ...
... metabolic disorders, gastrointestinal disorders, musculoskeletal disorders, and reproductive disorders. Shift work also can ... Chronobiology International. 29 (9): 1153-1175. doi:10.3109/07420528.2012.719971. PMID 23004349. S2CID 7565248. Ftouni, Suzanne ... Shift work sleep disorder is a circadian rhythm sleep disorder characterized by insomnia, excessive sleepiness, or both. Shift ... Shift work sleep disorder also creates a greater risk for human error at work. Shift work disrupts cognitive ability and ...
Jay, Sarah M.; Paterson, Jessica L.; Aisbett, Brad; Ferguson, Sally A. (2018). "Browse journals by subject". Chronobiology ... "problem drinkers were more than 2.5 times as likely to have been diagnosed with a depressive disorder or to have symptoms of ...
... bipolar disorder type II)". When a mood disorder recurs in a seasonal pattern it is described as a seasonal affective disorder ... Chronobiology International. 24 (4): 727-737. doi:10.1080/07420520701535795. PMID 17701683. S2CID 6071474. Petridou E.; ... The seasonal mood disorders that were recurrent in this study are as follows: "depression, 51%, and bipolar disorder, 49%, with ... Psychological disorders can be affected by seasonal changes and result in suicide. There is also a "physiological strain that ...
He is the editor-in-chief of the interdisciplinary journals Chronobiology International and Sexuality & Culture, as well as ... as recorded in newspaper articles on seasonal affective disorder, on daylight-saving time, on the pervasiveness of circadian ... "Editorial Board". Chronobiology International. Retrieved 2021-04-03. "Sexuality & Culture". Springer Science+Business Media. ...
... is intended to be a take-as-need drug for primary insomnia, circadian rhythm disorders, depression, as well as sleep ... Chronobiology International. 19 (5): 915-36. doi:10.1081/cbi-120014108. PMID 12405554. S2CID 10363563. Cardinali DP, Srinivasan ... In addition to a sleep aid, TIK-301 has been found useful in treating other disorders. Because of its affinity for serotonin ... TIK-301 has also been considered for use in patients with mild cognitive impairment (MCI) because of sleep disorder prevalence ...
In the field of chronobiology, melatonin has been found to be a key player in the synchrony of biological clocks. Melatonin ... In recent years, research with melatonin has shown to improve neurological disorders such as Parkinson's, Alzheimer's disease, ... Recently, scientists have been studying the relationship between the MT2 receptor and sleep disorders, anxiety, depression, and ...
Throughout the day, these proteins have different levels of disorder. The changing levels of disorder allow for a stable ... doi: 10.1126/science.1257277 PMID 25635104 Dunlap, J. C., Loros, J. J., & DeCoursey, P. J. (2004). Chronobiology: Biological ... all exhibit high amounts of intrinsic protein disorder. Intrinsically disordered proteins do not have a stable secondary ... Four years later in 2013, Dunlap and colleagues found that FRQ is an Intrinsically Disordered Protein whose stability is ...
After the discovery in the early 1980s of light therapy for seasonal affective disorder, at the National Institute of Mental ... He established the Clinical Chronobiology research program there in 1983 with funding from the National Institute of Mental ... It has also been used to correct the insomnia associated with delayed sleep phase disorder. Terman's animal studies showed that ... Wirz-Justice A, Benedetti F, Terman M (2009) Chronotherapeutics for Affective Disorders: A Clinician's Manual for Light and ...
Structural Chronobiology IMB coordinates a number of joint research initiatives with institutions in Mainz (Johannes Gutenberg ... Synthetic Biophysics of Protein Disorder Katja Luck: Integrative Systems Biology Brian Luke: Telomere Biology Christof Niehrs: ...
He also served on the boards of the National Institute of Health National Center on Sleep Disorders Research and the National ... "Chronobiology" for the 2010 edition of Principles and Practices of Sleep Medicine. Turek has published nearly 400 reviews and ... aimed at shifting the human clock in an attempt to alleviate mental and physical problems that are associated with disorders in ...
Chronobiology: Biological Timing in Health and Disease. Vol. 119. Academic Press. pp. 1-28. doi:10.1016/B978-0-12-396971- ... Robert Y. Moore (born December 5, 1931) is an American neurologist with interests in disorders of biological rhythms, movement ... disorders, and behavioral neurology. He is credited with discovering the function of the suprachiasmatic nucleus (SCN) as the ...
Chronobiology University of Geneva Circadian Rhythm suprachiasmatic nucleus Rev-ErbA alpha PER CRY BMAL1 alpha-amylase CRE ... "The genetics of mammalian circadian order and disorder: implications for physiology and disease". Nature Reviews Genetics. 9 ( ... His research has contributed significantly to the field of chronobiology and the understanding of circadian clocks in the body ... Schibler was thrust into the world of chronobiology on a single chance discovery. While examining transcription of serum ...
Rosenwasser AM (July 2010). "Circadian clock genes: non-circadian roles in sleep, addiction, and psychiatric disorders?". ... Protein pages needing a picture, Genes on human chromosome 22, Chronobiology, Protein kinases, Circadian rhythm). ...
"Use of Actigraphy for the Evaluation of Sleep Disorders and Circadian Rhythm Sleep-Wake Disorders: An American Academy of Sleep ... Chronobiology International. 30 (9): 1187-1196. doi:10.3109/07420528.2013.810222. ISSN 0742-0528. PMID 23998288. S2CID 4682794 ... "Use of Actigraphy for the Evaluation of Sleep Disorders and Circadian Rhythm Sleep-Wake Disorders: An American Academy of Sleep ... in affective disorders". Psychological Medicine. 35 (7): 939-944. doi:10.1017/S003329170500437X. PMID 16045060. Disorders That ...
"Sleep disorders linked to poor health and reduced occupational performance in police officers". National Sleep Foundation. Jan ... As a Team Leader of the Human Performance Factors, Sleep and Chronobiology Team at the NASA National Space Biomedical Research ... Münch M, Bromundt V (Dec 2012). "Light and chronobiology: implications for health and disease". Dialogues in Clinical ... Awarded by the Society for Research on Biological Rhythms for his contributions to the field of Chronobiology in 2001 The NIOSH ...
... panic disorder, anxiety disorders, and the movement disorder known as akathisia. It is a tranquilizer of the benzodiazepine ... Wollman M, Lavie P, Peled R (1985). "A hypernychthemeral sleep-wake syndrome: a treatment attempt". Chronobiology International ... Panic disorder with or without agoraphobia. Clonazepam has also been found effective in treating other anxiety disorders, such ... Coma Current alcohol use disorder Current substance use disorder Respiratory depression. In September 2020, the U.S. Food and ...
Williams GH, Dluhy RG (2008). "Chapter 336: Disorders of the Adrenal Cortex". In Loscalzo J, Fauci AS, Braunwald E, Kasper DL, ... Apoptosis - Programmed cell death in multicellular organisms Cerebral autoregulation Chronobiology - Field of biology ... An imbalance between excitation and inhibition is seen to be implicated in a number of neuropsychiatric disorders. The ...
... was a German scientist, known for his significant contributions to the field of Chronobiology, including some of ... and had important implications for understanding the cyclicity of many affective disorders. Wever's background in Physics ...
... study of color Chronobiology - study of biological rhythms Chrysology - study of precious metals Ciselure - art of chasing ... study and treatment of disorders of the foot; chiropody Podology - study of the feet Polemology - study of war Pomology - study ... study of hair and its disorders Trophology - study of nutrition Tsiganology - study of gypsies Turbology - study of tornadoes ...
Depression, chronic stress, bipolar disorder, etc. are considered mood disorders. It has been suggested that such disorders ... Chronobiology International. 31 (1): 114-22. doi:10.3109/07420528.2013.829845. PMID 24144242. S2CID 12007427. Nykamp K, ... mood disorder) and for anxiety disorders in women. Red meat is found to be protective against mood and anxiety disorders. ... There is a common mood disorder called Seasonal Affective Disorder (SAD) that often occurs during the winter months when there ...
It is said that those who experience this disorder usually have a history of major depressive or bipolar disorder, which may be ... Chronobiology International, 29, 780-785. Díaz-Morales, J.F., Jankowski, K.S., Vollmer, C., Randler, C. (2013). Morningness and ... Seasonal affective disorder is hypothesized to be caused by the diminishing exposure to environmental light which can lead to ... There are currently a few treatment therapies in order to help with seasonal affective disorder. The first line of therapy is ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRIHALOMETANOS. TRIHALOMETHANES. TRIHALOMETANOS. VACINA CONTRA DIFTERIA- ...
... neurotoxic disorders (neuropathology, chronobiology, diketone exposures, peripheral nervous effects, neurophysiology, ... trauma disorders from repetitive tasks, and ergonomics); occupational cancers (agricultural workers, agricultural chemicals, ... psychologic disorders from solvent exposures; respirators; control technology; and other occupational concerns. ... reproductive disorders (pesticides, fertility studies, mutagens, carbon-disulfide (75150), biotransformation, congenital ...
Animal Models for Disorders of Chronobiology: Cell and Tissue. Ramsey, K. M. & Bass, J., Nov 1 2010, Principles and Practice of ... Kushner, R. F. & Doerfler, B., Jan 1 2006, Obesity and Mental Disorders. CRC Press, p. 217-234 18 p.. Research output: Chapter ... Genetic basis of thyroid disorders. Kopp, P., 2006, Genomics and proteomics in molecular medicine. Ganten, D. & Ruekpaul, K. ( ...
The role of chronobiology in sleep disorders medicine. Sleep Medicine Reviews. 7: 455-73. PMID 15018090 DOI: 10.1016/S1087-0792 ... Hühne A, Welsh DK, Landgraf D. Prospects for Circadian Treatment of Mood Disorders. Annals of Medicine. 1-35. PMID 30265156 DOI ... The role of the circadian clock in animal models of mood disorders. Behavioral Neuroscience. 128: 344-59. PMID 24660657 DOI: ... Functional genetic variation in the Rev-Erbα pathway and lithium response in the treatment of bipolar disorder. Genes, Brain, ...
... neurotoxic disorders (neuropathology, chronobiology, diketone exposures, peripheral nervous effects, neurophysiology, ... trauma disorders from repetitive tasks, and ergonomics); occupational cancers (agricultural workers, agricultural chemicals, ... psychologic disorders from solvent exposures; respirators; control technology; and other occupational concerns. ... reproductive disorders (pesticides, fertility studies, mutagens, carbon-disulfide (75150), biotransformation, congenital ...
Sleep Technician Trainee, Sleep Disorders Clinic Centre for Sleep and Chronobiology. *Clinical Assistant, Unionville Family ...
... neurotoxic disorders (neuropathology, chronobiology, diketone exposures, peripheral nervous effects, neurophysiology, ... trauma disorders from repetitive tasks, and ergonomics); occupational cancers (agricultural workers, agricultural chemicals, ... psychologic disorders from solvent exposures; respirators; control technology; and other occupational concerns. ... reproductive disorders (pesticides, fertility studies, mutagens, carbon-disulfide (75150), biotransformation, congenital ...
Circadian rhythm sleep disorders in adolescents: clinical trials of combined treatments based on chronobiology. Psychiatry Clin ... Sleep disorders. Taking vitamin B12 by mouth does not seem to help people with sleep disorders. ... sleep disorders, depression, mental disorders, schizophrenia, weak bones (osteoporosis), swollen tendons, AIDS, inflammatory ... Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med 1988;318:1720- ...
His areas of academic interest include psychopharmacology, chronobiology, bipolar mood disorder and development of pragmatic ... Borderline Personality Disorder and currently leading a Decentralized Clinical Trial in Major Depressive Disorder. Thuy holds a ... Gary Sachs is the Therapeutic Area Leader in bipolar disease and mood disorders at Signant. He previously co-founded Concordant ... panelists will highlight the patient journey for a fully decentralized major depressive disorder (MDD) trial, including ...
Axelsson J, Bjorvatn B. F. Circadian rhythm sleep disorders. 2.1. Shift work. In: Sleep Medicine Textbook (second edition). Ed ... Bjorvatn, B., & Pallesen, S. (2021). F. Circadian rhythm sleep disorders. Clinical picture and diagnosis. In C. Bassetti, W. ... Pallesen, S., & Bjorvatn, B. (2021). F. Circadian rhythm sleep disorders. Health risks. In C. Bassetti, W. McNicholas, T. ... Bjorvatn B. F. Circadian rhythm sleep disorders. 1. Nosological classification, definitions, and epidemiology. In: Sleep ...
No article was found for Chronobiology Disorders and CRY1[original query]. File Formats Help:. How do I view different file ...
This is a brief guide to chronic insomia disorder. CBT-I is recommended as first-line treatment for chronic insomnia in adults ... What is chronic insomnia disorder?. The official Diagnostic Criteria for Chronic Insomnia Disorder provide an excellent "tick- ... Chronic insomnia is not just a sleep disorder; it also has an impact on daytime functioning, as listed above. It constitutes a ... History of the sleep disorder. v. Sleep diary. vi. Bed partner anamnesis (periodic leg movements in sleep/respiratory pauses) ...
Hes director of the medical chronobiology program in Brigham and Womens Hospitals Division of Sleep and Circadian Disorders ... or suffering from circadian rhythm disorders, said co-author Frank Scheer. ... door for a novel sleep/circadian behavioral strategy that might also benefit individuals experiencing mental health disorders ...
... a researcher in the Medical Chronobiology Program in the Brighams Division of Sleep and Circadian Disorders. "And we found ... Director of the Medical Chronobiology Program in the Brighams Division of Sleep and Circadian Disorders. "Previous research by ...
For those suffering bipolar disorder, strong midday light may have therapeutic qualities. A 2017 study in the American Journal ... "Chronobiology International, 2012. doi: 3109/07420528.2012.699356.. Jennings, J.; et al. "Can Dynamic Light Improve Melatonin ... They are also more prone to depression - a finding backed by extensive research on seasonal affective disorder (SAD), when some ... "Circadian Phase, Sleepiness, and Light Exposure Assessment in Night Workers with and Without Shift Work Disorder." ...
Chronobiology Disorders , Profiles RNS. Darsaud A, Bourdon L, Mercier S, Chapotot F, Bouteille B, Cespuglio R, Buguet A. Twenty ... Episode 9: Time and Our Bodies: Chronobiology. Time and Our Bodies: Chronobiology What is Chronobiology? Chronobiology is the ... Role of Chronobiology as a Transdisciplinary Field of Research: Its Applications in Treating Mood Disorders - Balkan Medical... ... chronobiology. In life, timing is everything. There is a new buzzword in cancer therapy, Chronobiology. Simply put, this means ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRANSTORNOS CRONOBIOLÓGICOS. CLATHRIN-COATED VESICLES. VESICULAS CUBIERTAS ...
CHRONOBIOLOGY DISORDERS. TRANSTORNOS CRONOBIOLÓGICOS. TRIHALOMETANOS. TRIHALOMETHANES. TRIHALOMETANOS. UNIONES ADHERENTES. ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRIHALOMETANOS. TRIHALOMETHANES. TRIHALOMETANOS. VACINA CONTRA DIFTERIA- ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRIHALOMETANOS. TRIHALOMETHANES. TRIHALOMETANOS. VACINA CONTRA DIFTERIA- ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRANSTORNOS CRONOBIOLÓGICOS. CLATHRIN-COATED VESICLES. VESICULAS CUBIERTAS ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRIHALOMETANOS. TRIHALOMETHANES. TRIHALOMETANOS. VACINA CONTRA DIFTERIA- ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRIHALOMETANOS. TRIHALOMETHANES. TRIHALOMETANOS. VACINA CONTRA DIFTERIA- ...
CHRONOBIOLOGY DISORDERS. TRANSTORNOS CRONOBIOLÓGICOS. TRIHALOMETANOS. TRIHALOMETHANES. TRIHALOMETANOS. UNIONES ADHERENTES. ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRANSTORNOS CRONOBIOLÓGICOS. CLATHRIN-COATED VESICLES. VESICULAS CUBIERTAS ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRANSTORNOS CRONOBIOLÓGICOS. CLATHRIN-COATED VESICLES. VESICULAS CUBIERTAS ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRIHALOMETANOS. TRIHALOMETHANES. TRIHALOMETANOS. VACINA CONTRA DIFTERIA- ...
CHRONOBIOLOGY DISORDERS. TRASTORNOS CRONOBIOLOGICOS. TRANSTORNOS CRONOBIOLÓGICOS. CLATHRIN-COATED VESICLES. VESICULAS CUBIERTAS ...
CHRONOBIOLOGY DISORDERS. TRANSTORNOS CRONOBIOLÓGICOS. TRIHALOMETANOS. TRIHALOMETHANES. TRIHALOMETANOS. UNIONES ADHERENTES. ...
  • Our findings provide evidence for the timing of food intake as a novel strategy to potentially minimize mood vulnerability in individuals experiencing circadian misalignment, such as people engaged in shift work, experiencing jet lag, or suffering from circadian rhythm disorders,' said co-author Frank Scheer. (healthday.com)
  • The findings highlight the need for further development of effective and energy-efficient methods for treatment of circadian rhythm disorders. (nasa.gov)
  • In patients with circadian rhythm disorders, melatonin agonists may be used. (medscape.com)
  • We spoke last month about the 21st Annual Psychopharmacology Update , the keynote lecture, the most underutilized therapies for major depression, bipolar disorder, and schizophrenia, and schizophrenia treatment in 2022 versus 2000. (globalacademycme.com)
  • We wanted to test the mechanisms that may explain why late eating increases obesity risk," explained senior author Frank A. J. L. Scheer, Ph.D., Director of the Medical Chronobiology Program in the Brigham's Division of Sleep and Circadian Disorders. (worldhealth.net)
  • said first author Nina Vujovic, Ph.D., a researcher in the Medical Chronobiology Program in the Brigham's Division of Sleep and Circadian Disorders. (worldhealth.net)
  • This study shows the impact of late vs. early eating," said senior study author Frank Scheer, director of the Medical Chronobiology Program in Brigham's Division of Sleep and Circadian Disorders. (safetyandhealthmagazine.com)
  • Author Frank AJL Scheer, PhD, director of Brigham's Division of Medical Chronobiology Program of Sleep and Circadian Disorders. (cittone-usa.com)
  • Hühne A, Welsh DK , Landgraf D. Prospects for Circadian Treatment of Mood Disorders. (neurotree.org)
  • Dr. Gary Sachs is the Therapeutic Area Leader in bipolar disease and mood disorders at Signant. (xtalks.com)
  • Dr. Sachs is a recognized expert clinical trialist with extensive experience in rater training and the methodologies of mood and anxiety disorder research. (xtalks.com)
  • The effects of common mental disorders (CMD), which usually include not only mood disorders but anxiety and substance abuse disorders, on both pregnant women and their babies have also drawn attention. (biomedcentral.com)
  • Circadian dysregulation and depressed mood commonly co-occur in young people, yet mechanisms linking Delayed Sleep-Wake Phase disorder (DSWPD) with depression are poorly understood. (edu.au)
  • Decreased serotonin signaling is associated with mood disorders, and a common way to treat mood disorders is with drugs that block serotonin reuptake to keep serotonin working for longer. (pennneuroknow.com)
  • J. Christian Gillin, a professor of psychiatry at the University of California, San Diego, conducts research on sleep, chronobiology and mood disorders. (lonniewatsonplumbing.com)
  • A possible role of perinatal light in mood disorders and internal cancers: reconciliation of instability and latitude concepts. (nel.edu)
  • Erren T, Koch M, Gross J, Reiter R, Meyer-Rochow V. A possible role of perinatal light in mood disorders and internal cancers: reconciliation of instability and latitude concepts. (nel.edu)
  • Interpersonal and social rhythm therapy (IPSRT), designed to stabilize daily routines as well as sleep and wake cycles, can improve mood and social functioning in patients with major depressive disorder (MDD), according to study results published in the American Journal of Psychotherapy . (psychiatryadvisor.com)
  • Marie Crowe, RN, PhD, of the department of psychological medicine, University of Otago Christchurch, New Zealand, and colleagues conducted a preliminary safety analysis of a randomized controlled trial of patients with a recurrent mood disorder who reported current cognitive difficulties. (psychiatryadvisor.com)
  • Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder. (neurotree.org)
  • For those suffering bipolar disorder, strong midday light may have therapeutic qualities. (bluezones.com)
  • 3-day conference on up-to-date, clinically relevant information in treatment of Depressive Disorder, ADHD, Schizophrenia, Bipolar Disorder, and Sleep Disorders. (globalacademycme.com)
  • Explore the latest advances in the treatment and management of Major Depressive Disorder, ADHD, Schizophrenia, and Bipolar Disorder, plus other clinically relevant hot topics: healthcare resilience, updates and innovations in fast-acting antidepressants, newly emerging digital therapeutics and updates in neuropsychiatry. (globalacademycme.com)
  • Few patients with schizophrenia, major depression, bipolar disorder, GAD, OCD, and personality disorders (like borderline or narcissistic personality disorders) achieve full remission and recovery. (globalacademycme.com)
  • They are also more prone to depression - a finding backed by extensive research on seasonal affective disorder (SAD), when some people grow depressed during the shorter winter days. (bluezones.com)
  • These symptoms go beyond merely feeling 'down' that the weather is colder, and are signs of a type of clinical depression called Seasonal Affective Disorder, or appropriately - SAD. (pennneuroknow.com)
  • Sufferers from winter-patterned Seasonal Affective Disorder (SAD) often link their emotional state to the seasons, with colder periods being anecdotally correlated to symptoms linked to the onset of depression. (imperialbiosciencereview.com)
  • At Circadian Eyewear we make sure our eyewear is based on the latest cutting edge scientific research, optic technology, and design by attending international eyewear conventions, consulting with health care professionals and research scientists in the fields of neuroscience, chronobiology, psychology, and light-therapy around the world. (circadianeyewear.com)
  • Our findings are applicable to about a third of the population in the industrialized world who consume food close to bedtime, as well as other populations who eat at night, including shift workers, or those experiencing jetlag or night-eating disorders, as well as those who routinely use melatonin supplements close to food intake," said Scheer, director of the Medical Chronobiology Program at Brigham and Women's Hospital, Boston, Massachusetts. (medscape.com)
  • Thuy Le Nguyen is a Senior Associate Director within the Study Management and Conduct of Clinical Operations at Boehringer Ingelheim Pharmaceuticals, Inc. Thuy has over 20 years of clinical research at BI, involved in many studies across different therapeutic areas including CNS, specifically in Alzheimer's Disease, Schizophrenia, Borderline Personality Disorder and currently leading a Decentralized Clinical Trial in Major Depressive Disorder. (xtalks.com)
  • Restless legs are a neurological disorder that affects an estimated 10 percent of the population. (andromenopause.com)
  • When a person develops addictions or neurological or psychological disorders, his or her way of relating to others is severely or very severely affected. (modafinil911.com)
  • He is recognized internationally as a leader in the field of nutritional influences in neurological disorders. (drperlmutter.com)
  • Chronopharmacology is now used as a routine to treat various disorders like hypertension, angina, cancer and various psychotic disorders. (who.int)
  • Attention Deficit Hyperactivity Disorder (ADHD) is one of the most prevalent mental disorders of childhood (with prevalence rates varying from 5% to 10%) and it can continue through adolescence and adulthood. (wcp-congress.com)
  • This session aims to describe a diversity of approaches in diagnosing and treating ADHD across the World with the emphasis on the latest studies on child, adolescent and adult Attention Deficit/Hyperactivity Disorder. (wcp-congress.com)
  • It may be useful for treating pediatric attention deficit hyperactivity disorder (ADHD), as well as enuresis and, possibly, pediatric-onset narcolepsy. (medscape.com)
  • When studying SAD, researchers look for distinguishing psychological, neurobiological or genetic factors that differentiate it from Major Depressive Disorder and other depressive disorders. (pennneuroknow.com)
  • Dysregulation in these neurotransmitters would mean that neurons change how they communicate with each other, which can lead to depressive disorders. (pennneuroknow.com)
  • Understanding how these neurotransmitters contribute to SAD symptoms is an important step in figuring out how to treat depressive disorders such as SAD. (pennneuroknow.com)
  • Frank Scheer HMS Professor of Medicine and Director of the Medical Chronobiology Program for the Division of Sleep and Circadian Disorders at Brigham and Women's. (vetclinpathjournal.org)
  • En este proyecto, los investigadores de NIOSH mantienen una colaboración continua con la Universidad del Estado de Nueva York en Buffalo para estudiar los efectos de las labores policiales y el estrés ocupacional en los marcadores tempranos (subclínicos) de la salud cardiovascular. (cdc.gov)
  • During this interactive discussion, panelists will highlight the patient journey for a fully decentralized major depressive disorder (MDD) trial, including methodology for centralized raters, real-time patient dosage monitoring, and patient behavior insights from measured digital biomarkers to evaluate depression. (xtalks.com)
  • Furthermore, it is coupled with an increased vulnerability to mental disorders, especially anxiety and depression. (cet.org)
  • Low vitamin D levels may be related to depression, rather than contributing to the disorder. (livewell2u.com)
  • According to a recent review, treating vitamin D deficiency in people with depression or other mental disorders may result in improvement in both long-term health and quality of life. (livewell2u.com)
  • Academic Dissertations;Academic Dissertations--South Carolina;Diagnostic and Statistical Manual of Mental Disorders;Depressive Disorder, Major;Factor Analysis, Statistical;Depression--ethnology;Mexican Americans;African Americans;European. (musc.edu)
  • There is a broad data base documenting the prevalence of insomnia disorder (ranging, for example, from about 6% - 20% in European countries). (cet.org)
  • Drake CL, Wright KP Jr. "Shift work, shift work disorder, and jet lag. (nasa.gov)
  • In Circadian-Rhythm-Sleep-Disorders a considerable shift of the individual circadian rhythm is the concealed, biological reason for patient symptoms. (pzafiropoulos.gr)
  • The official Diagnostic Criteria for Chronic Insomnia Disorder provide an excellent "tick-off-list" to determine what symptoms are present, and if they conform to this difficult-to-treat sleep disturbance. (cet.org)
  • Symptoms of this disorder range from uncomfortable tingling to "creepy crawly" sensations in the arms and legs. (andromenopause.com)
  • Participants included 2,118 treatment-seeking adults who self-reported their eating-related symptoms on the Eating Disorder Questionnaire. (eurekamag.com)
  • Logistic regression analysis revealed history of psychiatric disorder, past interpersonal traumatic experience, and feeling pressure to have a child were associated with CMD. (biomedcentral.com)
  • Though heritable influences on psychiatric disorders have been known since the inception of modern psychiatry, it is only recently that precise genetics risk factors have been identified. (wcp-congress.com)
  • Further studies will be needed to establish if changes in meal timing can help people with depressive- and anxiety-related disorders, she said. (healthday.com)
  • Future studies are needed to determine whether changes in meal times can help people with depressive and anxiety/anxiety-related disorders. (cittone-usa.com)
  • Chronobiology mechanisms and circadian sleep disorders. (nasa.gov)
  • Chronobiology is the biology of time and internal biological clocks . (lookformedical.com)
  • The use of IPSRT among patients with major depressive disorder has a strong theoretical rationale on the basis of the principles of chronobiology, and this study suggests that this therapy may be effective in practice," the investigators concluded. (psychiatryadvisor.com)
  • The science of chronobiology quantifies the time structure characterizing each physiologic variable, its genetically anchored and mostly environmentally synchronized chronome. (lookformedical.com)
  • Or you can use the brainier definition, Chronobiology is the quantitative study of rhythmic temporal relationships in biological phenomena. (lookformedical.com)
  • In this study, we asked whether the time we eat matters when everything else is consistent," said first author Nina Vujović, a researcher in the Medical Chronobiology Program. (vetclinpathjournal.org)
  • This study suggests that BN is less common whereas BED and OSFED are more common among midlife eating disorder treatment-seeking individuals relative to younger controls. (eurekamag.com)
  • Coincidentally, most patients that suffer from restless leg syndrome also have this disorder. (andromenopause.com)
  • Additionally, midlife and younger patients with BED and OSFED differed on several demographic (e.g., marital status) and eating disorder-related characteristics (e.g. (eurekamag.com)
  • The negative effects at the cognitive level may be such that the person may develop psychological problems related to behavioral disorders. (modafinil911.com)
  • Vitamin B12 is injected into the body for pernicious anemia , to prevent and treat vitamin B12 deficiency, and to prevent and treat a nervous system disorder called myelopathy, which can occur in people who are vitamin B12 deficient. (emedicinehealth.com)
  • Our findings open the door for a novel sleep/circadian behavioral strategy that might also benefit individuals experiencing mental health disorders,' Chellappa said in the release. (healthday.com)
  • Researchers soon hope to use our genetics to more specifically treat disorders of all kinds, including diseases like SAD. (pennneuroknow.com)
  • Two participants (1.1 %) met the criteria for major depressive disorder. (biomedcentral.com)
  • As with the more commonly known Major Depressive Disorder, SAD is a complicated disorder with many contributing factors. (pennneuroknow.com)
  • For now, treatments for SAD are similar to treatments for Major Depressive Disorder. (pennneuroknow.com)
  • Thus, we can hypothesize that insomnia treatment may be a successful strategy to prevent mental disorders. (cet.org)
  • Former and present mental disorders ii. (cet.org)
  • Common mental disorders (CMD) during pregnancy can have a clearly harmful influence on both mothers and children. (biomedcentral.com)
  • Some studies have reported related factors for mental disorders, such as region-specific background. (biomedcentral.com)
  • Eleven participants (6.2 %) met the criteria for one or more diagnoses, with 2 participants having two mental disorders and 3 having three mental disorders. (biomedcentral.com)
  • Well being Coach Exhibit right now is putting attention on mental wellness, whether it is depressive disorder, fear or anxiety. (erbediaphrodite.com)
  • One of the most terrifying nighttime disorders that you can have involves abnormal behavior during the REM part of rest. (andromenopause.com)
  • There are different manifestations and indeed classifications, with antisocial behavior disorder, oppositional defiant disorder and impulse control disorder being the most representative. (modafinil911.com)
  • We also compared demographic and eating disorder-related characteristics across diagnoses and age groups. (eurekamag.com)
  • Neurologic disorders caused by exposure to toxic substances through ingestion, injection, cutaneous application, or other method. (uchicago.edu)
  • He's director of the medical chronobiology program in Brigham and Women's Hospital's Division of Sleep and Circadian Disorders in Boston. (healthday.com)
  • Attention to these differences and similarities is necessary to understand eating disorders in midlife. (eurekamag.com)
  • Chronobiology is a field of biology that examines timing processes, including periodic (cyclic) phenomena in living organisms, such as their adaptation to solar- and lunar-related rhythms. (lookformedical.com)
  • Most movement disorders can take place at night and during the day, however, PLMD occurs exclusively during the nighttime hours. (andromenopause.com)
  • No article was found for Chronobiology Disorders and CRY1[original query] . (cdc.gov)
  • Is the Subject Area "Chronobiology" applicable to this article? (plos.org)