Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include, but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.Shock, Hemorrhagic: Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.Heat-Shock Proteins: Proteins which are synthesized in eukaryotic organisms and bacteria in response to hyperthermia and other environmental stresses. They increase thermal tolerance and perform functions essential to cell survival under these conditions.Shock, Cardiogenic: Shock resulting from diminution of cardiac output in heart disease.Shock, Traumatic: Shock produced as a result of trauma.HSP70 Heat-Shock Proteins: A class of MOLECULAR CHAPERONES found in both prokaryotes and in several compartments of eukaryotic cells. These proteins can interact with polypeptides during a variety of assembly processes in such a way as to prevent the formation of nonfunctional structures.Heat-Shock Response: A constellation of responses that occur when an organism is exposed to excessive heat. Responses include synthesis of new proteins and regulation of others.High-Energy Shock Waves: High-amplitude compression waves, across which density, pressure, and particle velocity change drastically. The mechanical force from these shock waves can be used for mechanically disrupting tissues and deposits.Hot Temperature: Presence of warmth or heat or a temperature notably higher than an accustomed norm.HSP90 Heat-Shock Proteins: A class of MOLECULAR CHAPERONES whose members act in the mechanism of SIGNAL TRANSDUCTION by STEROID RECEPTORS.HSP27 Heat-Shock Proteins: A subfamily of small heat-shock proteins that function as molecular chaperones that aid in refolding of non-native proteins. They play a protective role that increases cellular survival during times of stress.Chaperonin 60: A group I chaperonin protein that forms the barrel-like structure of the chaperonin complex. It is an oligomeric protein with a distinctive structure of fourteen subunits, arranged in two rings of seven subunits each. The protein was originally studied in BACTERIA where it is commonly referred to as GroEL protein.HSP72 Heat-Shock Proteins: Stress-inducible members of the heat-shock proteins 70 family. HSP72 heat shock proteins function with other MOLECULAR CHAPERONES to mediate PROTEIN FOLDING and to stabilize pre-existent proteins against aggregation.Electroshock: Induction of a stress reaction in experimental subjects by means of an electrical shock; applies to either convulsive or non-convulsive states.Resuscitation: The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)Cold Shock Proteins and Peptides: Cellular proteins and peptides that are induced in response to cold stress. They are found in a broad variety of prokaryotic and eukaryotic organisms.Electric Countershock: An electrical current applied to the HEART to terminate a disturbance of its rhythm, ARRHYTHMIAS, CARDIAC. (Stedman, 25th ed)Shock, Surgical: A type of shock that occurs as a result of a surgical procedure.Lactams, Macrocyclic: LACTAMS forming compounds with a ring size of approximately 1-3 dozen atoms.Benzoquinones: Benzene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.HSC70 Heat-Shock Proteins: A constitutively expressed subfamily of the HSP70 heat-shock proteins. They preferentially bind and release hydrophobic peptides by an ATP-dependent process and are involved in post-translational PROTEIN TRANSLOCATION.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Heat-Shock Proteins, Small: A family of low molecular weight heat-shock proteins that can serve as MOLECULAR CHAPERONES.Chaperonins: A family of multisubunit protein complexes that form into large cylindrical structures which bind to and encapsulate non-native proteins. Chaperonins utilize the energy of ATP hydrolysis to enhance the efficiency of PROTEIN FOLDING reactions and thereby help proteins reach their functional conformation. The family of chaperonins is split into GROUP I CHAPERONINS, and GROUP II CHAPERONINS, with each group having its own repertoire of protein subunits and subcellular preferences.Molecular Chaperones: A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.Transcription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.Osmotic Pressure: The pressure required to prevent the passage of solvent through a semipermeable membrane that separates a pure solvent from a solution of the solvent and solute or that separates different concentrations of a solution. It is proportional to the osmolality of the solution.Superantigens: Microbial antigens that have in common an extremely potent activating effect on T-cells that bear a specific variable region. Superantigens cross-link the variable region with class II MHC proteins regardless of the peptide binding in the T-cell receptor's pocket. The result is a transient expansion and subsequent death and anergy of the T-cells with the appropriate variable regions.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Bacterial Proteins: Proteins found in any species of bacterium.HSP40 Heat-Shock Proteins: A family of heat-shock proteins that contain a 70 amino-acid consensus sequence known as the J domain. The J domain of HSP40 heat shock proteins interacts with HSP70 HEAT-SHOCK PROTEINS. HSP40 heat-shock proteins play a role in regulating the ADENOSINE TRIPHOSPHATASES activity of HSP70 heat-shock proteins.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Transcription, Genetic: The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.DNA-Binding Proteins: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.Lipopolysaccharides: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)Fluid Therapy: Therapy whose basic objective is to restore the volume and composition of the body fluids to normal with respect to WATER-ELECTROLYTE BALANCE. Fluids may be administered intravenously, orally, by intermittent gavage, or by HYPODERMOCLYSIS.Stress, Physiological: The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions.Cold Temperature: An absence of warmth or heat or a temperature notably below an accustomed norm.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Defibrillators, Implantable: Implantable devices which continuously monitor the electrical activity of the heart and automatically detect and terminate ventricular tachycardia (TACHYCARDIA, VENTRICULAR) and VENTRICULAR FIBRILLATION. They consist of an impulse generator, batteries, and electrodes.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Enterotoxins: Substances that are toxic to the intestinal tract causing vomiting, diarrhea, etc.; most common enterotoxins are produced by bacteria.HSP110 Heat-Shock Proteins: A group of eukaryotic high-molecular mass heat-shock proteins that represent a subfamily of HSP70 HEAT-SHOCK PROTEINS. Hsp110 proteins prevent protein aggregation and can maintain denatured proteins in folding-competent states.Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.HSP20 Heat-Shock Proteins: A subfamily of small heat-shock proteins that are closely related to ALPHA B-CRYSTALLIN. Hsp20 heat-shock proteins can undergo PHOSPHORYLATION by CYCLIC GMP-DEPENDENT PROTEIN KINASES.alpha-Crystallin B Chain: One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE.HSP47 Heat-Shock Proteins: Basic glycoprotein members of the SERPIN SUPERFAMILY that function as COLLAGEN-specific MOLECULAR CHAPERONES in the ENDOPLASMIC RETICULUM.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Chaperonin 10: A group I chaperonin protein that forms a lid-like structure which encloses the non-polar cavity of the chaperonin complex. The protein was originally studied in BACTERIA where it is commonly referred to as GroES protein.Promoter Regions, Genetic: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.HSP30 Heat-Shock Proteins: A subfamily of small heat-shock proteins found in a wide variety of organisms.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Endotoxins: Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.Electrophoresis, Gel, Two-Dimensional: Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.Gene Expression Regulation, Bacterial: Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.Escherichia coli Proteins: Proteins obtained from ESCHERICHIA COLI.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Heat Stress Disorders: A group of conditions that develop due to overexposure or overexertion in excessive environmental heat.Intra-Aortic Balloon Pumping: Counterpulsation in which a pumping unit synchronized with the patient's electrocardiogram rapidly fills a balloon in the aorta with helium or carbon dioxide in early diastole and evacuates the balloon at the onset of systole. As the balloon inflates, it raises aortic diastolic pressure, and as it deflates, it lowers aortic systolic pressure. The result is a decrease in left ventricular work and increased myocardial and peripheral perfusion.Avoidance Learning: A response to a cue that is instrumental in avoiding a noxious experience.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Sigma Factor: A protein which is a subunit of RNA polymerase. It effects initiation of specific RNA chains from DNA.Arsenites: Inorganic salts or organic esters of arsenious acid.Bacterial Toxins: Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Saccharomyces cerevisiae: A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Crystallins: A heterogeneous family of water-soluble structural proteins found in cells of the vertebrate lens. The presence of these proteins accounts for the transparency of the lens. The family is composed of four major groups, alpha, beta, gamma, and delta, and several minor groups, which are classed on the basis of size, charge, immunological properties, and vertebrate source. Alpha, beta, and delta crystallins occur in avian and reptilian lenses, while alpha, beta, and gamma crystallins occur in all other lenses.Saline Solution, Hypertonic: Hypertonic sodium chloride solution. A solution having an osmotic pressure greater than that of physiologic salt solution (0.9 g NaCl in 100 ml purified water).alpha-Crystallins: A subclass of crystallins that provides the majority of refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Alpha-crystallins also act as molecular chaperones that bind to denatured proteins, keep them in solution and thereby maintain the translucency of the lens. The proteins exist as large oligomers that are formed from ALPHA-CRYSTALLIN A CHAIN and ALPHA-CRYSTALLIN B CHAIN subunits.Molecular Weight: The sum of the weight of all the atoms in a molecule.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.HeLa Cells: The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.Staphylococcus aureus: Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.Equipment Failure: Failure of equipment to perform to standard. The failure may be due to defects or improper use.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Mice, Inbred C57BLKinetics: The rate dynamics in chemical or physical systems.Drosophila melanogaster: A species of fruit fly much used in genetics because of the large size of its chromosomes.Sodium Compounds: Inorganic compounds that contain sodium as an integral part of the molecule.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Cell Nucleus: Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Systemic Inflammatory Response Syndrome: A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA 90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Defibrillators: Cardiac electrical stimulators that apply brief high-voltage electroshocks to the HEART. These stimulators are used to restore normal rhythm and contractile function in hearts of patients who are experiencing VENTRICULAR FIBRILLATION or ventricular tachycardia (TACHYCARDIA, VENTRICULAR) that is not accompanied by a palpable PULSE. Some defibrillators may also be used to correct certain noncritical dysrhythmias (called synchronized defibrillation or CARDIOVERSION), using relatively low-level discharges synchronized to the patient's ECG waveform. (UMDNS, 2003)Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Electrophoresis, Polyacrylamide Gel: Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.Protein Biosynthesis: The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS.Adaptation, Physiological: The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.Isotonic Solutions: Solutions having the same osmotic pressure as blood serum, or another solution with which they are compared. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)Quinones: Hydrocarbon rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Kidney Calculi: Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE.Oxidative Stress: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).Genes, Bacterial: The functional hereditary units of BACTERIA.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Rifabutin: A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Conditioning (Psychology): A general term referring to the learning of some particular response.Gene Expression Regulation, Fungal: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in fungi.Splanchnic Circulation: The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.Mouth FloorImmunoblotting: Immunologic method used for detecting or quantifying immunoreactive substances. The substance is identified by first immobilizing it by blotting onto a membrane and then tagging it with labeled antibodies.Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.Punishment: The application of an unpleasant stimulus or penalty for the purpose of eliminating or correcting undesirable behavior.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Saccharomyces cerevisiae Proteins: Proteins obtained from the species SACCHAROMYCES CEREVISIAE. The function of specific proteins from this organism are the subject of intense scientific interest and have been used to derive basic understanding of the functioning similar proteins in higher eukaryotes.Up-Regulation: A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.Heating: The application of heat to raise the temperature of the environment, ambient or local, or the systems for accomplishing this effect. It is distinguished from HEAT, the physical property and principle of physics.Conditioning, Classical: Learning that takes place when a conditioned stimulus is paired with an unconditioned stimulus.Intensive Care Units: Hospital units providing continuous surveillance and care to acutely ill patients.Nitric Oxide: A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Neoplasm Proteins: Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.Mice, Inbred BALB CFear: The affective response to an actual current external danger which subsides with the elimination of the threatening condition.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Hospital Mortality: A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Blotting, Northern: Detection of RNA that has been electrophoretically separated and immobilized by blotting on nitrocellulose or other type of paper or nylon membrane followed by hybridization with labeled NUCLEIC ACID PROBES.Plasmids: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.Hyperthermia, Induced: Abnormally high temperature intentionally induced in living things regionally or whole body. It is most often induced by radiation (heat waves, infra-red), ultrasound, or drugs.Menstrual Hygiene Products: Personal care items used during MENSTRUATION.Ureteral Calculi: Stones in the URETER that are formed in the KIDNEY. They are rarely more than 5 mm in diameter for larger renal stones cannot enter ureters. They are often lodged at the ureteral narrowing and can cause excruciating renal colic.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Panstrongylus: A genus of cone-nosed bugs of the subfamily TRIATOMINAE. Its species are vectors of TRYPANOSOMA CRUZI.DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Tumor Cells, Cultured: Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.Recombinant Fusion Proteins: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.Plasma Substitutes: Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.Acclimatization: Adaptation to a new environment or to a change in the old.Cell Line, Tumor: A cell line derived from cultured tumor cells.Quercetin: A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Vasoconstrictor Agents: Drugs used to cause constriction of the blood vessels.Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).Osmosis: Tendency of fluids (e.g., water) to move from the less concentrated to the more concentrated side of a semipermeable membrane.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Cytoprotection: The process by which chemical compounds provide protection to cells against harmful agents.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Enzyme Activation: Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.Oxygen: An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Cold-Shock Response: A constellation of responses that occur when an organism is exposed to excessive cold. In humans, a fall in skin temperature triggers gasping, hypertension, and hyperventilation.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Cardiac Output: The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).Protein Folding: Processes involved in the formation of TERTIARY PROTEIN STRUCTURE.APACHE: An acronym for Acute Physiology and Chronic Health Evaluation, a scoring system using routinely collected data and providing an accurate, objective description for a broad range of intensive care unit admissions, measuring severity of illness in critically ill patients.Hydroxyethyl Starch Derivatives: Starches that have been chemically modified so that a percentage of OH groups are substituted with 2-hydroxyethyl ether groups.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Cytoplasm: The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Critical Illness: A disease or state in which death is possible or imminent.Tampons, Surgical: Plugs or cylinders made of cotton, sponge, or other absorbent material. They are used in surgery to absorb fluids such as blood or drainage.Random Allocation: A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.Adenosine Triphosphate: An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.Fungal Proteins: Proteins found in any species of fungus.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Interleukin-6: A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.Prostaglandins A: (13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid (PGA(1)); (5Z,13E,15S)-15-hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid (PGA(2)); (5Z,13E,15S,17Z)-15-hydroxy-9-oxoprosta-5,10,13,17-tetraen-1-oic acid (PGA(3)). A group of naturally occurring secondary prostaglandins derived from PGE; PGA(1) and PGA(2) as well as their 19-hydroxy derivatives are found in many organs and tissues.Streptococcus pyogenes: A species of gram-positive, coccoid bacteria isolated from skin lesions, blood, inflammatory exudates, and the upper respiratory tract of humans. It is a group A hemolytic Streptococcus that can cause SCARLET FEVER and RHEUMATIC FEVER.Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.TrehaloseAssisted Circulation: Pumping that aids the natural activity of the heart. (Dorland, 27th ed)beta-Galactosidase: A group of enzymes that catalyzes the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-galactosides. Deficiency of beta-Galactosidase A1 may cause GANGLIOSIDOSIS, GM1.CanavanineNitric Oxide Synthase Type II: A CALCIUM-independent subtype of nitric oxide synthase that may play a role in immune function. It is an inducible enzyme whose expression is transcriptionally regulated by a variety of CYTOKINES.Critical Care: Health care provided to a critically ill patient during a medical emergency or crisis.Adenosine Triphosphatases: A group of enzymes which catalyze the hydrolysis of ATP. The hydrolysis reaction is usually coupled with another function such as transporting Ca(2+) across a membrane. These enzymes may be dependent on Ca(2+), Mg(2+), anions, H+, or DNA.Protein Structure, Tertiary: The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Escape Reaction: Innate response elicited by sensory stimuli associated with a threatening situation, or actual confrontation with an enemy.Cardiopulmonary Resuscitation: The artificial substitution of heart and lung action as indicated for HEART ARREST resulting from electric shock, DROWNING, respiratory arrest, or other causes. The two major components of cardiopulmonary resuscitation are artificial ventilation (RESPIRATION, ARTIFICIAL) and closed-chest CARDIAC MASSAGE.Oligonucleotide Array Sequence Analysis: Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.Hydrogen Peroxide: A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
Shell Shock: A Gus Conrad Thriller, Harley House Press, 2015. In 2015, Northwestern University, his alma mater, honored him by ... Stahl's Illustrated: Chronic Pain and Fibromyalgia. Cambridge University Press, New York, New York 2009. Stahl's Self ... In addition to his many academic contributions, Stahl is known for his 2015 novel Shell Shock and his expert contribution to ... Stahl, Stephen M. (July 2015). Shell Shock: A Gus Conrad Thriller. Harley House Press. ASIN B00ZIY17I2. "Stephen Stahl academic ...
Munjed Al Muderis
Current evidence of extracorporeal shock wave therapy in chronic Achilles tendinopathy. impact factor 1.53. In this paper Al ... "Current evidence of extracorporeal shock wave therapy in chronic Achilles tendinopathy". Int J Surg. 24: 154-9. doi:10.1016/j. ... Percutaneous Epidural Lysis of Adhesions in Chronic Lumbar Radicular Pain: A Randomized, Double-Blind, Placebo-Controlled Trial ... "Percutaneous epidural lysis of adhesions in chronic lumbar radicular pain: a randomized, double-blind, placebo-controlled trial ...
... and severe cases of septic shock) Heart Disease (myocardial infarction- heart attack; acute or chronic congestive or other ... many cases of cardiogenic shock- e.g., after a myocardial infarction or during heart failure; distributive shock, hypovolemic ... A general failure is one that occurs across a wide range of locations in the body, such as systemic shock after the loss of a ... This form is sometimes called peripheral vascular failure, shock or peripheral vascular shutdown. A milder or preliminary form ...
"Clinical evidence of peroxynitrite formation in chronic renal failure patients with septic shock". Free Radical Biology & ... Increased level of nitrotyrosine is detected in rheumatoid arthritis septic shock and coeliac disease. In all these studies ... Kaur H; Halliwell B (1994). "Evidence for nitric oxide-mediated oxidative damage in chronic inflammation Nitrotyrosine in serum ...
Peter B. Cotton
Lawrence, C.; Siddiqi, M. F.; Hamilton, J. N.; Keane, T. E.; Romagnuolo, J.; Hawes, R. H.; Cotton, P. B. (2010). "Chronic ... Calcific Pancreatitis: Combination ERCP and Extracorporeal Shock Wave Lithotripsy for Pancreatic Duct Stones". Southern Medical ... disability and resource utilisation in chronic pancreatitis: A prospective cohort study". Gut. 60 (1): 77-84. doi:10.1136/gut. ...
"Extracorporeal shock wave therapy is effective in treating chronic plantar fasciitis: a meta-analysis of RCTs". Clin Orthop ... "Is Extracorporeal Shock Wave Therapy Clinical Efficacy for Relief of Chronic, Recalcitrant Plantar Fasciitis? A Systematic ... Zhiyun L, Tao J, Zengwu S (July 2013). "Meta-analysis of high-energy extracorporeal shock wave therapy in recalcitrant plantar ... Monto R (April 2014). "Platelet-rich plasma efficacy versus corticosteroid injection treatment for chronic severe plantar ...
Chronic urinary retention that is due to bladder blockage which can either be as a result of muscle damage or neurological ... Other patients may develop a shock-like condition and may require admission to a hospital. Serious complications of untreated ... In chronic retention, ultrasound of the bladder may show massive increase in bladder capacity (normal capacity is 400-600 ml). ... The chronic form of urinary retention may require some type of surgical procedure. While both procedures are relatively safe, ...
Social risk management
Supporting risk pooling and creative initiatives for economic shocks and chronic risks. Discouraging widowhood rituals, harmful ... shocks. Many more mechanisms are available for coping with idiosyncratic shocks than covariant shocks. The latter can be ... 2. Idiosyncratic shocks vs. covariant shocks: Some sources lead to losses in only some households in a community like ... Repeated shocks: A third distinction concerns shocks following one another like drought followed by sickness and death versus ...
Periodic episodes of acute hemorrhage are possible and may be severe, leading to shock and death. Inadequate nutrition or the ... Approximately 80 percent of cases will develop chronic thrombocytopenia. ... Haemorrhage from ruptured bullae, epistaxis or gastrointestinal bleeding is severe and may cause shock and death. Onyalai is an ... Treatment is directed at the prevention of haemorrhagic shock. Standard dose prednisolone does not increase the platelet count ...
Hypovolemic shock can be life-threatening as it can very quickly starve the body of the oxygen-rich blood that it needs to ... Chronic pancreatitis may develop as a result of acute pancreatitis. It is most commonly due to many years of heavy alcohol use ... In chronic pancreatitis these tests may be normal. Medical imaging such as ultrasound and CT scan may also be useful. Acute ... New cases of chronic pancreatitis develop in about 8 per 100,000 people a year and currently affect about 50 per 100,000 people ...
... can become chronic and then become completely asymptomatic. Disseminated strongyloidiasis occurs when patients ... with chronic strongyloidiasis become immunosuppressed. It presents with abdominal pain, distension, shock, pulmonary and ... On acquiring the infection, there may be respiratory symptoms (Löffler's syndrome). The infection may then become chronic with ... It is often recommended that patients being started on immunosuppression be screened for chronic strongyloidiasis; however, ...
"High-energy extracorporeal shock-wave therapy for treating chronic calcific tendinitis of the shoulder: a systematic review". ... In those with calcific tendinitis of the shoulder high energy extracorporeal shock-wave therapy (which uses sound waves) can be ... If these do not work extracorporeal shock wave therapy or surgery may be considered. Analgesics and nonsteroidal anti- ... eMedicine on Calcific Tendonitis Extracorporeal shock wave therapy (subscription required). ...
"High-energy extracorporeal shock-wave therapy for treating chronic calcific tendinitis of the shoulder: a systematic review". ... In those with calcific tendinitis of the shoulder high energy extracorporeal shock-wave therapy can be useful. It is not useful ... if injury affects normal work/activities as well as details on the actual shoulder problem including acute versus chronic and ...
Finally, a shock phase can develop as fluids start to leak through the damaged colon lining. This can result in shock and ... Symptoms may come on more slowly in those with acute on chronic disease. Signs and symptoms of chronic disease include ... Acute mesenteric ischemia was first described in 1895 while chronic disease was first described in the 1940s. Chronic disease ... Chronic disease is a risk factor for acute disease. The best method of diagnosis is angiography, with computer tomography (CT) ...
Chronic cholecystitis may be asymptomatic, may present as a more severe case of acute cholecystitis, or may lead to a number of ... In cases of severe inflammation, shock, or if the person has higher risk for general anesthesia (required for cholecystectomy ... Play media Chronic cholecystitis occurs after repeated episodes of acute cholecystitis and is almost always due to gallstones. ... Without treatment, chronic cholecystitis may occur. The word is from Greek, cholecyst- meaning "gallbladder" and -itis meaning ...
Extracorporeal shockwave therapy
"Efficacy of extracorporeal shock wave therapy for the treatment of chronic pelvic pain syndrome: a randomized, controlled trial ... "Is extracorporeal shock wave therapy clinical efficacy for relief of chronic, recalcitrant plantar fasciitis? A systematic ... The shock waves are abrupt, high amplitude pulses of mechanical energy, similar to soundwaves, generated by an electromagnetic ... There are a growing number of double blind sham controlled studies that show success rates of up to 80%. Shock waves stimulate ...
In chronic attacks, there is a possibility of the victim going into shock and dying from the attack. Depending on the severity ... Acute and chronic reactions have the same symptoms but for chronic reactions, the symptoms are much more severe. Farmer's lung ... For chronic FLD, there is no true treatment because the patient has developed hypersensitivity meaning their FLD could last the ... It results in a type III hypersensitivity inflammatory response and can progress to become a chronic condition which is ...
Animal models of depression
Also, most of the symptoms do not persist long enough following cessation of the uncontrollable shock. Chronic mild stress: The ... LH is induced in one day or over several days of repeated inescapable stress by the treating of tail shock or foot shock in ... It might simply result from a high intensity of chronic stressor caused by chronic sensory deprivation. This model shows high ... It aims to model a chronic depressive-like state that develops gradually over time in response to stress, and they can provide ...
ECTRIMS 2005; accessed 11-Sep-2007 Baker M, Shock A, Parton T et al. Pharmacokinetic and pharmacodynamic properties of the VLA- ... Effect of CDP323, a small molecule VLA-4 antagonist, on chronic experimental allergic encephalomyelitis in C57Bl/6 mice. ... Zaurategrast was investigated in chronic experimental autoimmune encephalomyelitis (EAE) in mice. The drug was effective when ...
Successful use of chronic epoprostenol as a bridge to liver transplant in severe PPHTN. Transplant 1998 4:457 Kuo PC, Johnson ... Aerosolized prostacyclin and INO in septic shock: Different effects on splanchnic oxygenation. Intensive Care Med 1996;22:880-7 ... Cardiopulmonary complications in chronic liver disease. World J Gastroenterol 2006;12;526-538 Christman et al. An imbalance ... Imatinib, designed to treat chronic myeloid leukemia, has been shown to reverse the pulmonary remodeling associated with PPH. ...
Costa ML, Shepstone L, Donell ST, Thomas TL (2005). "Shock wave therapy for chronic Achilles tendon pain: a randomized placebo- ... Tendinosis, sometimes called chronic tendinitis, chronic tendinopathy, or chronic tendon injury, is damage to a tendon at a ... Shock-wave therapy (SWT) may be effective in treating calcific tendinosis in both humans and rats. In rat subjects, SWT ... Chen YJ, Wang CJ, Yang KD, Kuo YR, Huang HC, Huang YT, Sun YC, Wang FS (2004). "Extracorporeal shock waves promote healing of ...
Extracorporeal shockwave therapy
"Is extracorporeal shock wave therapy clinical efficacy for relief of chronic, recalcitrant plantar fasciitis? A systematic ... As of 2018 use of ESWT had been studied as a potential treatment for chronic prostatitis/chronic pelvic pain syndrome in three ... "Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome". The Cochrane Database of ... Beginning in 1969 and funded by the German Ministry of Defense, Dornier began a study of the effects of shock waves on tissue. ...
Chronic lameness may make the horse load the limb unevenly, even if the lameness may be in hock or stifle. Insufficient Bone ... The horse tends to grow long-toes with low heels, moving the hoof tubules in horizontal direction, and so it reduces shock ... 1] A sloping shoulder has better shock-absorption and provides a comfortable ride because it sets the withers back, so a rider ... The horse loses shock absorption ability, potentially contributing to the development of navicular syndrome, sole bruising, ...
V. A. Cecilioni on Chizzola Maculae, describing the skin lesion as a diagnostic tool for the identification of chronic fluoride ... Waldbott is noted for his fundamental research on human anaphylaxis and penicillin shock, allergy-induced respiratory problems ... This was the first association between tobacco smoking and chronic respiratory disease. Up until that point, the condition was ... 1930-1989 at UMass Amherst The Preskeletal Phase of Chronic Fluoride Intoxication. ...
As stated chronic inflammation is linked to most chronic diseases including arthritis, many types of cancer, cardiovascular ... Vasodilation and organ dysfunction are serious problems associated with widespread infection that may lead to septic shock and ... Chronic inflammation In acute inflammation, if the injurious agent persists then chronic inflammation will ensue. This process ... Both chronic and extreme inflammation are associated with disruptions of anabolic signals initiating muscle growth. Chronic ...
That same year, suffering from a chronic heart condition, she moved to a small cottage on the grounds of the Motion Picture & ... After working on several more movies, she suffered delayed shock over her husband's death and had a nervous breakdown. During ... "shocking" novel written by Allison Mackenzie should be banned from the school library, and received good reviews for her ...
This drop from an academic education to a vocational one likely came as a shock. His fellow students were generally of a ... his wife began showing early signs of the chronic paranoid schizophrenia she would later be diagnosed with. ... some of whom were shocked. Many outside commentators believed the dissolution was a ruse, and that the CPK was actually ...
Hematopoietic stem cell transplantation
Chronic graft-versus-host disease may also develop after allogeneic transplant. It is the major source of late treatment- ... This puts a patient at high risk of infections, sepsis and septic shock, despite prophylactic antibiotics. However, antiviral ... Graft versus tumor is mainly beneficial in diseases with slow progress, e.g. chronic leukemia, low-grade lymphoma, and in some ... In addition to inflammation, chronic graft-versus-host disease may lead to the development of fibrosis, or scar tissue, similar ...
Bengal famine of 1943
Pre-famine shocks and distressEdit. Throughout 1942 and into early 1943, military and political events combined with natural ... leading to a chronic and growing shortage of rice. Its inability to keep pace with rapid population growth changed it from ... These processes left social and economic groups mired in poverty and indebtedness, unable to cope with the economic shocks they ... and a shock event (such as war or political interference in markets) that disrupts the economic market for food. When these ...
Index of HIV/AIDS-related articles
East End of London
Staphylococcal scalded skin syndrome
Artificial cardiac pacemaker
Shock chamber. Antitachycardia pacing chamber. Tachycardia detection. Antibradycardia pacing chamber O = None. O = None. E = ... "Treatment of chronic heart block with the Lucas induction coil pacemaker" (PDF). Br Heart J. 33 (6): 938-42. doi:10.1136/hrt. ... capable of delivering electrical shocks for dangerously fast abnormal ventricular rhythms. ...
Urinary tract infection
Chronic prostatitis in the forms of chronic prostatitis/chronic pelvic pain syndrome and chronic bacterial prostatitis (not ... Vaginitis may also be due to a yeast infection. Interstitial cystitis (chronic pain in the bladder) may be considered for ... Persons with spinal cord injury are at increased risk for urinary tract infection in part because of chronic use of catheter, ... Nicolle LE (2001). "The chronic indwelling catheter and urinary infection in long-term-care facility residents". Infect Control ...
پرتو کیهانی - ویکیپدیا، دانشنامهٔ آزاد
At distances of ≈94 AU from the Sun, the solar wind undergoes a transition, called the termination shock, from supersonic to ... The region between the termination shock and the heliopause acts as a barrier to cosmic rays, decreasing the flux at lower ... Shock front acceleration (theoretical model for supernovae and active galactic nuclei): Incident proton gets accelerated ... As an explanation of the acceleration in supernovae and active galactic nuclei the model of shock front acceleration is used. ...
Amyotrophic lateral sclerosis
Gardner A, Iverson G, McCrory P (January 2014). "Chronic traumatic encephalopathy in sport: a systematic review". British ... and electric shock. There is a tentative association with exposure to various pesticides, including the organochlorine ... A 2016 review of 16 meta-analyses concluded that there was convincing evidence for an association with chronic occupational ... Some NFL players thought to have died from ALS may have actually had chronic traumatic encephalopathy (CTE), a ...
The discovery was part of a continuing study on circulatory shock and proteolytic enzymes related to the toxicology of snake ... and is presumed to play a role in chronic pain. This receptor has been also described to play a role in inflammation. Most ... of bradykinin has led to a new understanding of many physiological and pathological phenomena including circulatory shock ...
Tumor necrosis factor alpha
chronic inflammatory response to antigenic stimulus. • cellular response to organic cyclic compound. • positive regulation of ... Clark IA (July 1982). "Suggested importance of monokines in pathophysiology of endotoxin shock and malaria". Klin. Wochenschr. ... positive regulation of chronic inflammatory response to antigenic stimulus. • negative regulation of growth of symbiont in host ... Whereas high concentrations of TNF induce shock-like symptoms, the prolonged exposure to low concentrations of TNF can result ...
University of Texas Health Science Center at San Antonio
The word tachycardia came to English from New Latin as a neoclassical compound built from the combining forms tachy- + -cardia, which are from the Greek ταχύς tachys, "quick, rapid" and καρδία, kardia, "heart". As a matter both of usage choices in the medical literature and of idiom in natural language, the words tachycardia and tachyarrhythmia are usually used interchangeably, or loosely enough that precise differentiation is not explicit. Some careful writers have tried to maintain a logical differentiation between them, which is reflected in major medical dictionaries and major general dictionaries. The distinction is that tachycardia be reserved for the rapid heart rate itself, regardless of cause, physiologic or pathologic (that is, from healthy response to exercise or from cardiac arrhythmia), and that tachyarrhythmia be reserved for the pathologic form (that is, an arrhythmia of the rapid rate type). This is why five of the previously referenced ...
... it may be able to withstand weather-related shocks. But if these shocks overwhelm the ecosystem's line of defense, it is ... Despite repeated stated intentions by the world's leaders to end hunger and famine, famine remains a chronic threat in much of ... Papaioannou, Kostadis J. (January 2016). "Climate shocks and conflict: Evidence from colonial Nigeria". Political Geography. 50 ... Papaioannou, Kostadis (June 2017). "Weather shocks and agricultural commercialization in colonial tropical Africa: did cash ...
In those with chronic symptoms, a mild elevation of C-reactive protein (CRP) has been observed, suggesting ongoing chronic ... "Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock". Journal of Virology. 86 ... Chronic arthritis. In those who have more than two weeks of arthritis, ribavirin may be useful. The effect of ... Chronic disease. Observations during recent epidemics have suggested chikungunya may cause long-term symptoms following ...
In one example, mice were conditioned to fear a strong scent, acetophenone, by accompanying the smell with an electric shock. ... physiological and behavioral changes observed following chronic drug exposure (60,95,97,102). New frontiers of research ... Mice were trained, using foot shocks, to fear a cherry blossom odor. The investigators reported that the mouse offspring had an ... Despite the offspring never experiencing the electric shock themselves the mice still display a fear of the acetophenone scent ...
Posttraumatic stress disorder
Predictor models have consistently found that childhood trauma, chronic adversity, and familial stressors increase risk for ... shell shock, battle fatigue, combat stress reaction, or traumatic war neurosis. Some of these terms date back to the ... "shell shock" and "combat neurosis". The term "posttraumatic stress disorder" came into use in the 1970s in large part due ... "shell shock" in the First World War to the "battle fatigue" in the Second World War, to "operational exhaustion" in the Korean ...
Economic history of the Russian Federation
Other shock. Cardiogenic shock. Distributive shock. Anaphylaxis. Obstructive shock. Neurogenic shock. Spinal shock. Organ ... Chronic severe hepatic disease. *HIV infection in association with a last known CD4 count of ,50/mm3 ... Shock sequence. SIRS. Sepsis. Severe sepsis. Septic shock. Multiple organ dysfunction syndrome. ... Angus, Derek C.; van der Poll, Tom (29 August 2013). "Severe Sepsis and Septic Shock". New England Journal of Medicine. 369 (9 ...
Chronic cases require steroid therapy, which generally leads to a good response. In cases where allergic attack is progressing ... Chronic radiation keratosis. Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy. Radiation acne. ... Electric shock. *Drowning. *Lightning injuries. Ungrouped skin conditions resulting from physical factors. *Dermatosis neglecta ...
Dre's breakthrough album The Chronic in 1992, and enjoyed several years of chart successes for artists including 2Pac, Dr. Dre ... "16 Label Changes That Shocked The Rap Game - Snoop Dogg Leaves Death Row". Complex.com. Retrieved July 23, 2016 ... The Chronic, went on to Triple Platinum status in the United States by the end of 1993. It also made a career for Dre's ...
Nuclear and radiation accidents and incidents
People with chronic maladies, including cancer and diabetes, are also especially susceptible to infection. These opportunistic ... equisimilis strain causing streptococcal toxic shock syndrome (STSS)". BMC Genomics. 12: 17. doi:10.1186/1471-2164-12-17. ISSN ... Occasionally it is isolated from skin, but usually in relation to a chronic skin condition or some breach of the epithelial ...
Cell-Wave Study: Combined Extracorporal Shock Wave Therapy and Intracoronary Cell Therapy in Chronic Ischemic Myocardium - Full...
Cell-Wave Study: Combined Extracorporal Shock Wave Therapy and Intracoronary Cell Therapy in Chronic Ischemic Myocardium. The ... Effect of shock wave-facilitated intracoronary cell therapy on LVEF in patients with chronic heart failure: the CELLWAVE ... Active Comparator: Placebo shock-wave treatment & cell therapy Procedure: intracoronary stem cell therapy extracorporal shock ... Active Comparator: low-dose shock-wave treatment & Cell therapy Procedure: intracoronary stem cell therapy extracorporal shock ...
Shock treatment may cure chronic depression: study | Deccan Herald
Shock treatment can provide an effective alternative for people suffering from major depression who do not respond to ... Shock treatment can provide an effective alternative for people suffering from major depression who do not respond to ... sometimes referred to as shock treatment, change certain areas of the brain that play a role in how people feel, learn and ... Shock treatment may cure chronic depression: study Shock treatment may cure chronic depression: study. ...
Heat-shock proteins induce T-cell regulation of chronic inflammation
Immune responses to certain heat-shock proteins (HSPs) develop in almost all inflammatory diseases; however, the significance ... Heat-shock proteins induce T-cell regulation of chronic inflammation Nat Rev Immunol. 2005 Apr;5(4):318-30. doi: 10.1038/ ... Immune responses to certain heat-shock proteins (HSPs) develop in almost all inflammatory diseases; however, the significance ... and in initial clinical trials in patients with chronic inflammatory disease, HSP-derived peptides have been shown to promote ...
Extracorporeal shock wave treatment for chronic lateral epicondylitis (tennis elbow)
... for chronic lateral epicondylitis (CLE) of the elbow (elbow tendonitis or tennis elbow). These waves may help to accelerate the ... or piezoelectric devices are used to translate energy into acoustic waves during extracorporeal shock wave treatment (ESWT) ... Extracorporeal shock wave treatment for chronic lateral epicondylitis (tennis elbow) Issues Emerg Health Technol. 2007 Jan;(96 ... for chronic lateral epicondylitis (CLE) of the elbow (elbow tendonitis or tennis elbow). These waves may help to accelerate the ...
Neuroprotective effect of small heat shock protein, Hsp27, after acute and chronic alcohol administration. - PubMed - NCBI
Neuroprotective effect of small heat shock protein, Hsp27, after acute and chronic alcohol administration.. Toth ME1, Gonda S, ... In this study, we investigated the neuroprotective effect of small heat shock protein, Hsp27, after acute and chronic ethanol ... Neuroprotective effect of small heat shock protein, Hsp27, after acute and chronic alcohol administration ... Neuroprotective effect of small heat shock protein, Hsp27, after acute and chronic alcohol administration ...
feeling electrical shocks throughout my body? - Chronic Pain - HealingWell.com Forum
HealingWell.com Forum , Diseases & Conditions , Chronic Pain , feeling electrical shocks throughout my body? ... YEs i have had shocks in my body down to my toes for 2 yrs. Then i saw a massage therapist. After about 3 wks they let up alot ... I get the shock-thing and buzzing when Im stressed. Your neighbors may have put an extra load of stress on your body. ... Im scared to tell my DR because hell just want to set up the referral to shock my limbs. I get that enough as it is right now ...
Heat shock proteins and chronic fatigue in primary Sjögren's syndrome
Chronic fatigueinnate immunitycellular stressheat shock proteinsautoimmune diseasesSjögrens syndrome ... Heat shock proteins and chronic fatigue in primary Sjögrens syndrome. Type. Journal article ... When the innate immune system is activated, heat shock proteins (HSPs) are produced to protect cells. Some extracellular HSPs ... Thus, extracellular HSPs, particularly HSP90α, may signal fatigue in chronic inflammation. This supports the hypothesis that ...
Efficacy of Extracorporal Shock Wave Therapy in Patient With Chronic Non-bacterial Prostatitis / Chronic Pelvic Pain Syndrome -...
Efficacy of Extracorporal Shock Wave Therapy in Patient With Chronic Non-bacterial Prostatitis / Chronic Pelvic Pain Syndrome. ... Extracorporal Shock Wave Therapy Chronic Non-bacterial Prostatitis Chronic Pelvic Pain Syndrome Device: standars ... Chronic pelvic pain existence for more than three month and certain diagnosis of chronic non-bacterial / chronic pelvic pain ... The Efficacy of Extracorporal Shock Wave Therapy on Symptoms Relief in Patients With Chronic Non-bacterial Prostatitis / ...
Short-term outcomes of extracorporeal shock wave therapy for the treatment of chronic non-calcific tendinopathy of the...
Frontiers | T Cell-Mediated Chronic Inflammatory Diseases Are Candidates for Therapeutic Tolerance Induction with Heat Shock...
Heat shock proteins (HSP) have shown disease suppressive activities in many models of experimental autoimmune diseases through ... Heat shock proteins (HSP) have shown disease suppressive activities in many models of experimental autoimmune diseases through ... Failing immunological tolerance for critical self-antigens is the problem underlying most chronic inflammatory diseases of ... Failing immunological tolerance for critical self-antigens is the problem underlying most chronic inflammatory diseases of ...
SHOCK! Opioid Drugs Help Those With Chronic Pain
The Washington Post-Kaiser Family Foundation polled those with chronic pain and the majority said the drugs have helped them ... That neednt be the reason not to use something that truly does help to manage chronic pain (at the very least, chronic pain ... I have chronic pain from arthritis. Despite telling every medico I see that I dont want and will not take opioid-based pain ... RT @Mutnodjmet: SHOCK! Opioid Drugs Help Those With Chronic Pain. Stop punishing those who need these medicines. https://t.co/ ...
Saliva as a Biomarker of Heat Shock Protein in Chronic Renal Disease | OMICS International
Heat shock protein 70 usually located in the cytoplasm, it plays an important role has a chaperone. It said to have anti- ... Saliva as a Biomarker of Heat Shock Protein in Chronic Renal Disease Mithra N Hegde1, Nireeksha2* and Shilpa Shetty3 ... The role of heat shock proteins in chronic renal damage, their protective and deleterious effect is of prime importance for the ... The role of heat shock proteins in chronic renal damage, their protective and deleterious effect is of prime importance for the ...
PRIME PubMed | Patients With Chronic Obstructive Pulmonary Disease Are at Higher Risk for Pneumonia, Septic Shock, and Blood...
Septic Shock, and Blood Transfusions After Total Shoulder Arthroplasty. Download Prime PubMed App to iPhone, iPad, or Android ... Patients With Chronic Obstructive Pulmonary Disease Are at Higher Risk for Pneumonia, ... Patients With Chronic Obstructive Pulmonary Disease Are at Higher Risk for Pneumonia, Septic Shock, and Blood Transfusions ... "Patients With Chronic Obstructive Pulmonary Disease Are at Higher Risk for Pneumonia, Septic Shock, and Blood Transfusions ...
Frontiers | Heat Shock Protein 70 Serum Levels Differ Significantly in Patients with Chronic Hepatitis, Liver Cirrhosis, and...
Herein, the prognostic relevance of serum Hsp70 levels in patients with chronic hepatitis (CH; n=50), liver cirrhosis (LC; n=46 ... Herein, the prognostic relevance of serum Hsp70 levels in patients with chronic hepatitis (CH; n=50), liver cirrhosis (LC; n=46 ... Patients with chronic hepatitis (CH, n=50) revealed significantly higher Hsp70 serum levels compared to the control group, ... Patients with chronic hepatitis (CH, n=50) revealed significantly higher Hsp70 serum levels compared to the cont... ...
Effect of Shock Wave-Facilitated Intracoronary Cell Therapy on LVEF in Patients With Chronic Heart Failure: The CELLWAVE...
Effect of Shock Wave-Facilitated Intracoronary Cell Therapy on LVEF in Patients With Chronic Heart Failure: The CELLWAVE ... Keywords: Carbamates, Chronic Disease, Stem Cells, Germany, Single-Blind Method, Magnetic Resonance Imaging, Cell- and Tissue- ... Effect of Shock Wave-Facilitated Intracoronary Cell Therapy on LVEF in Patients With Chronic Heart Failure: The CELLWAVE ... Regional wall thickening improved significantly in the shock wave + BMCs group (3.6%; 95% CI, 2.0%-5.2%), but not in the shock ...
Treatment for painful calcified chronic pancreatitis: extracorporeal shock wave lithotripsy versus endoscopic treatment: a...
Pilot studies suggest that extracorporeal shock wave lithotripsy (ESWL) alone relieves pain in calcified chronic pancreatitis. ... Treatment for painful calcified chronic pancreatitis: extracorporeal shock wave lithotripsy versus endoscopic treatment: a ... Treatment for painful calcified chronic pancreatitis: extracorporeal shock wave lithotripsy versus endoscopic treatment: a ... Background: In chronic pancreatitis, obstruction of the main pancreatic duct (MPD) may contribute to the pathogenesis of pain. ...
Short-term outcomes of extracorporeal shock wave therapy for the treatment of chronic non-calcific tendinopathy of the...
There is evidence supporting the use of extracorporeal shock wave therapy (ESWT) in calcific tendinopathy of the rotator cuff, ... From: Short-term outcomes of extracorporeal shock wave therapy for the treatment of chronic non-calcific tendinopathy of the ... ESWT, indicates extracorporeal shock wave therapy; ADL, activity of daily living; ROM, range of motion; CMS, Constant and ...
Dialysis Complications of Chronic Renal Failure: Practice Essentials, Electrolyte Abnormalities, Neurologic Complications
Hypotension and shock. Hypotension in dialysis patients may be due to any of the causes encountered in any other patient. ... encoded search term (Dialysis Complications of Chronic Renal Failure) and Dialysis Complications of Chronic Renal Failure What ... Dialysis Complications of Chronic Renal Failure Updated: Nov 18, 2019 * Author: Richard S Krause, MD; Chief Editor: Erik D ... Cardiac arrest in a patient with chronic renal failure or ESRD may be due to hyperkalemia. Consider treatment with IV calcium ...
Chronic Abdominal Pain & Nephrolithiasis & Shock<...
Shock Symptom Checker: Possible causes include Pelvic Inflammatory Disease, Acute Pancreatitis, Nephrolithiasis. Check the full ... 492 Possible Causes for Chronic Abdominal Pain, Nephrolithiasis, Shock * Pelvic Inflammatory Disease ... Differential diagnoses, possible causes and diseases for Chronic Abdominal Pain, Nephrolithiasis, Shock listed by probability ... Chronic abdominal pain Case 16: Trouble sleeping Case 17[amboss.com] If untreated, sepsis with shock, vascular collapse, ...
Day 4 Shocking! Not Drinking Enough Water Makes Your Respiratory System Suffer, Science Says
3. Chronic dehydration can cause breathing problems. Dehydration causes some of the white cells to convert the amino acid ... Day 4 Shocking! Not Drinking Enough Water Makes Your Respiratory System Suffer, Science Says. Ricky Tang. Editor. Movie Lover. ... Day 4 Shocking! Not Drinking Enough Water Makes Your Respiratory System Suffer, Science Says 10 Satirical Illustrations Showing ... Day 4 Shocking! Not Drinking Enough Water Makes Your Respiratory System Suffer, Science Says 10 Satirical Illustrations Showing ...
Timing of endoscopy after extracorporeal shock wave lithotripsy for chronic pancreatitis
... LAUR Repository. Login , Help ... Timing of endoscopy after extracorporeal shock wave lithotripsy for chronic pancreatitis. Azar, Riad; Merrill, Joseph T. ... Timing of endoscopy after extracorporeal shock wave lithotripsy for chronic pancreatitis. Pancreas, 40(7), 1087-1090. ... Objectives: Extracorporeal shock wave lithotripsy (ESWL) and endoscopic retrograde cholangiopancreatography (ERCP) are used to ...
Results matching category of Chronic Disease Indicators, type of Filtered Views, and topic of toxic-shock syndrome ...
Shock wave therapy is effective for chronic calcifying tendinitis of the shoulder
SHOCK WAVE is a multifunctional device used in orthopedics, physiotherapy, sports medicine, urology and veterinary medicine. ... Shock wave therapy is effective for chronic calcifying tendinitis of the shoulder Type: Free Shock-wave therapy is effective ... We agree with previous authors that high-energy shock-wave therapy should be considered before surgery for chronic calcific ... For medical use, shock waves of approximately 0.001 to 0.4 mJ/mm2 are applied. It is useful to differentiate low-energy shock ...
Medical mystery: A shocking heart ailment - Philly
Medical mystery: A shocking heart ailment Updated: July 14, 2017 - 1:52 PM EDT * ... The electrical shock that John had while awake likely helped create a perfect storm in which the effects of the medication, ... He gave me permission to share his story, and wanted me to emphasize that he vividly remembers the shock he had in the ER while ... But Johns ICD had been set to deliver a shock only if his heart rate was greater than 160 beats per minute, which never ...
Preventing Chronic Disease: October 2008: 07 0239
Shock. 1 (3.0). Injury. 3 (9.1). Fall with subdural hematoma. 1 (3.0). ... National Center for Chronic Disease Prevention and Health Promotion. United States Department of Health and Human Services. ... Chronic disease in health emergencies: in the eye of the hurricane. Prev Chronic Dis 2006;3(2). http://www.cdc.gov/pcd/issues/ ... We similarly could not assess chronic conditions and need for medical care referrals in nonsponsored shelters. The EED data are ...
Chronic Pain Initial Assessment
Streptococcal Toxic Shock Syndrome | CDC
Streptococcal toxic shock syndrome (STSS) is a rare, but serious bacterial infection. STSS can develop very quickly into low ... Chronic illnesses: People with diabetes or alcohol use disorder, previously known as alcohol dependence or alcoholism, are at ... Streptococcal toxic shock syndrome (STSS) is a rare, but serious bacterial infection. STSS can develop very quickly into low ... They often need fluids given through a vein and other treatments to help treat shock and organ failure. Many people with STSS ...
The efficacy of extracorporeal shock wave therapy for chronic coccydynia | Virtual Health Sciences Library
The efficacy of extracorporeal shock wave therapy for chronic coccydynia Aydın Canan Gönen; Örsçelik, Aydan;Gök, Mustafa Cantay ... Extra-corporeal shock wave therapy (ESWT) is used to treat several painful musculoskeletal disorders.. Subjects and Methods: ... Citation: Canan Gönen Aydın ,Aydan Örsçelik ,Mustafa Cantay Gök ,Yunus Emre Akman , The efficacy of extracorporeal shock wave ... The medical records of 34 patients (29 females, 5 males) who had been treated with ESWT between 2017 and 2018 for chronic ...
Bride's shock at groom's unthinkable act | Northern Star
Pathologists identify signature brain injury of 'shell shock'
... chronic pain. One died of a gunshot wound to the head, and one died of multiple organ failure. The researchers compared the ... After World War I, mass bombardments of troops were rare, and shell shock became uncommon. Now renamed blast neurotrauma or ... The research team may have found the signature of shell shock, or blast neurotrauma, a mysterious ailment that has afflicted ... A century after the first reported cases of shell shock, the struggle to overcome this invisible injury continues. Doctors ...
Extracorporal Shock Wave TherapyESWTTherapyTreatment of plantar fasciitisWaveWavesSeptic shockObstructiveInflammationCardiogenicToxic-shock syExtracorporeal shock wave applicationRenal failureCardiacIschemicLithotripsyComplicationsHigh-Energy Shock WavesDisordersSystemicTreatmentDiseasesHeatFatigueESWLSyndromeDiagnosesSymptomsSpinal Cord IHepatitisElectrical shockDiabetesDiagnosed with chronic renal dExacerbations
Extracorporal Shock Wave Therapy1
- There is both a high-energy and low-energy form of shock wave treatment, and both forms of therapy can be used in the treatment of these conditions. (verywell.com)
- Shock wave therapy is thought to work by inducing microtrauma to the tissue that is affected by these problems. (verywell.com)
- Few complications have been reported with the use of shock wave therapy. (verywell.com)
- Shock wave therapy is quite expensive, and whether or not it is an effective treatment is controversial. (verywell.com)
- The jury is still out on whether or not shock wave therapy is an effective treatment for these orthopedic conditions. (verywell.com)
- It is important that patients try more traditional treatments for a period of at least 6 months to a year before considering shock wave therapy. (verywell.com)
- Patients who have no success with these traditional treatments may benefit from shock wave therapy. (verywell.com)
- Therefore, in patients who have chronic plantar fasciitis , and who have failed a minimum six month trial of standard treatments, shock wave therapy is a safe treatment alternative to surgery. (verywell.com)
- Extracorporeal Shock Wave Therapy is prescribed for patients who have experienced plantar fasciitis for an extended period of time -- six months or more -- and have not benefited from other conservative treatments. (nysportspodiatry.com)
- Clinical studies show a 70 percent success rate for treatment of plantar fasciitis using Extracorporeal Shock Wave Therapy. (nysportspodiatry.com)
Treatment of plantar fasciitis1
- Low-energy shock wave treatments are given as a series of three or more treatments. (verywell.com)
- On the other hand, the high-energy shock wave treatments are given at one session. (verywell.com)
- High-energy shock wave treatments are quite painful, and often some type of anesthesia is needed. (verywell.com)
- Since that time, numerous studies have investigated the use of shock wave treatments for these problems. (verywell.com)
- However, there are also numerous reports that have not been as successful and show no significant difference when shock wave treatment is compared to more standard treatments of these problems. (verywell.com)
- The most attractive aspect of shock wave treatment is that it is a noninvasive option for problems that are sometimes challenging to treat. (verywell.com)
- If the shock wave treatments are helpful, the difference is small. (verywell.com)
- Therefore, a significant number of patients will still have pain after shock wave treatments. (verywell.com)
- Evaluation of low-energy extracorporeal shock-wave application for treatment of chronic plantar fasciitis. (verywell.com)
- Chronic obstructive pulmonary disease (COPD) has been associated with several complications after surgery, including pneumonia, myocardial infarction, septic shock, and mortality. (unboundmedicine.com)
- In light of the increased risk of these serious complications, surgeons should have a lower threshold of suspicion for infection in patients with COPD after TSA so that adequate measures can be taken before developing severe infectious complications including pneumonia and septic shock. (unboundmedicine.com)
- No septic shock or other severe complications occurred. (symptoma.com)
- We present a case of a urinary tract infection secondary to Pediococcus pentosaceus causing septic shock and acute kidney injury in a 70-year-old male. (symptoma.com)
- Sepsis or septic shock is systemic inflammatory response syndrome (SIRS) secondary to a documented infection (see Shock Classification, Terminology, and Staging). (medscape.com)
- Detrimental host responses to infection occupy a continuum that ranges from sepsis to septic shock and multiple organ dysfunction syndrome (MODS). (medscape.com)
- The hallmarks of sepsis and septic shock are changes that occur at the microvascular and cellular level with diffuse activation of inflammatory and coagulation cascades, vasodilation and vascular maldistribution, capillary endothelial leakage, and dysfunctional utilization of oxygen and nutrients at the cellular level. (medscape.com)
- 42 had severe disease, and of those, 25 had severe sepsis or septic shock and 12 died. (cdc.gov)
- Standard definitions were used for organ system failures and severe sepsis and septic shock ( 5 ). (cdc.gov)
- Septic shock is defined as a subset of sepsis in which underlying circulatory and cellular metabolism abnormalities are profound enough to substantially increase mortality. (scribd.com)
- Early detection of sepsis and septic shock followed by rapid and proper resuscitation and management will results in good outcomes. (scribd.com)
- Septic shock is associated with high mortality. (plos.org)
- Norepinephrine is an accepted treatment for hypotension in septic shock. (plos.org)
- 65 mmHg, and adverse events in patients with septic shock receiving norepinephrine peripherally in an intermediate care unit. (plos.org)
- From a retrospective chart review of 91 patients with septic shock treated with norepinephrine for hypotension, ward mortality, 30-, 60- and 90-day mortality, standardized mortality ratio (SMR) and adverse events (necrosis and arrhythmia) were analysed. (plos.org)
- Elderly patients with septic shock treated with norepinephrine displayed a better survival in the ward and at 30 days than expected. (plos.org)
- Hallengren M, Åstrand P, Eksborg S, Barle H, Frostell C (2017) Septic shock and the use of norepinephrine in an intermediate care unit: Mortality and adverse events. (plos.org)
- As most patients presenting with SCI and spinal shock have also suffered significant trauma and are at risk for hypovolemic shock as well as for "obstructive"/"mechanical" shock (cardiac tamponade, tension pneumothorax), efforts should be made to rule-out and treat all these reversible causes of shock. (clinicaladvisor.com)
- 1 In the early 1960s, Moran Campbell recognised the danger of hypercapnic respiratory failure (carbon dioxide retention) caused by high concentrations of oxygen in the treatment of acute exacerbations of chronic obstructive pulmonary disease. (bmj.com)
- 3 4 Evidence on the benefits and harms of the use of oxygen in acute exacerbations of chronic obstructive pulmonary disease has led all specialties in the United Kingdom to recommend controlled oxygen treatment with a target saturation range (usually 88-92%) in this condition. (bmj.com)
- 10.1136/bmj.c5462 ) finally fills this gap, and it provides robust evidence that the routine administration of high concentration oxygen in acute exacerbations of chronic obstructive pulmonary disease is associated with increased mortality. (bmj.com)
- 7 The trial compared high concentration oxygen treatment with titrated oxygen treatment in the pre-hospital setting in 405 patients with a presumed acute exacerbation of chronic obstructive pulmonary disease. (bmj.com)
- In the subgroup of patients with confirmed chronic obstructive pulmonary disease (n=214) mortality was reduced even further (0.22, 0.05 to 0.91). (bmj.com)
- 8 Cardiac troponin concentrations are raised in about 25% of patients with acute exacerbations of chronic obstructive pulmonary disease and positively correlate with the degree of hypercapnia and acidosis. (bmj.com)
- 9 Many patients with acute exacerbations of chronic obstructive pulmonary disease have coexisting ischaemic heart disease, and high oxygen concentrations may increase the risk of death by causing myocardial damage as a result of reduced coronary blood flow. (bmj.com)
- The 9% mortality in patients given high concentration oxygen treatment in Austin and colleagues' study is comparable to the 7.4% mortality reported in a 2003 UK national audit of acute exacerbations of chronic obstructive pulmonary disease. (bmj.com)
- Streptococcal toxic shock syndrome (STSS) is a rare, but serious bacterial infection. (cdc.gov)
- Initial gram staining of blood cultures showed gram-positive cocci in chains, suggesting streptococcal toxic shock syndrome (STSS). (qxmd.com)
- Toxic shock syndrome (TSS) is a life-threatening acute illness resulting from bacterial exotoxins, which act as superantigens to produce an overwhelming cytokine release throughout the body. (psychiatryadvisor.com)
- Streptococcus pyogenes produces various virulence factors that determine the pathogenesis and invasiveness of the bacteria, including those known as M-proteins, several of which are thought to be specific for GAS toxic shock syndrome. (psychiatryadvisor.com)
- Diagnostic Confirmation: Are you sure your patient has toxic shock Syndrome? (psychiatryadvisor.com)
Extracorporeal shock wave application2
- The present trial investigated the effects of combining target-tissue preconditioning by extracorporeal shock wave application with intracoronary infusion of autologous BMCs on LV function in patients with chronic postinfarction HF. (acc.org)
- Location modalities for focused extracorporeal shock wave application in the treatment of chronic plantar fasciitis. (agfisicos.com)
- For more information, see Chronic Renal Failure . (medscape.com)
- Hyperkalemia is the most common clinically significant electrolyte abnormality in chronic renal failure. (medscape.com)
- Serum potassium levels usually should be measured in patients with chronic renal failure or ESRD who present with a systemic illness or major injury. (medscape.com)
- Chronic Renal Failure. (routledge.com)
- What is the effect of targeted cardiac shock wave pretreatment with subsequent application of bone marrow-derived mononuclear cells (BMCs) on recovery of left ventricular ejection fraction (LVEF) in patients with chronic heart failure (CHF)? (acc.org)
- Chronic antiocoagulation for cardiac conditions -- Ch. 29. (epa.gov)
- Pilot studies suggest that extracorporeal shock wave lithotripsy (ESWL) alone relieves pain in calcified chronic pancreatitis. (bmj.com)
- Extracorporeal shock wave lithotripsy seems to be inefficient for these composite stones. (symptoma.com)
- Nephrolithiasis [ncbi.nlm.nih.gov] Occurrence of gross hematuria several months after the extracorporeal shock wave, lithotripsy (ESWL) treatment lead to hospitalization. (symptoma.com)
- Common bile duct and pancreatic injury are rare complications following extracorporeal shock wave lithotripsy. (symptoma.com)
- PURPOSE: To evaluate predictors of the success rate for one session of shock wave lithotripsy (SWL), focusing on the relationships between pretreatment hydronephrosis grade [ncbi.nlm.nih.gov] A 62-year-old man was admitted to our hospital with complaints of abdominal pain and rectal bleeding. (symptoma.com)
- Objectives: Extracorporeal shock wave lithotripsy (ESWL) and endoscopic retrograde cholangiopancreatography (ERCP) are used to clear main pancreatic duct (MPD) stones and alleviate pain in patients with chronic pancreatitis. (edu.lb)
- The shock waves used for lithotripsy can induce frag- mentation and destruction of solid bodies. (exonmedical.com)
High-Energy Shock Waves1
- Shock treatment can provide an effective alternative for people suffering from major depression who do not respond to conventional medications, researchers, including one of Indian-origin, claim. (deccanherald.com)
- NIH Chronic Prostatitis Symptom Index (NIH-CPSI) is used to evaluate symptom severity and response to treatment in these patients. (clinicaltrials.gov)
- ESWL is a safe and effective preferred treatment for selected patients with painful calcified chronic pancreatitis. (bmj.com)
- MAVIT - The device for erectile dysfunction and chronic prostatitis treatment. (alibaba.com)
- Treatment of elevated intraocular pressure (IOP) in patients with chronic open-angle glaucoma and intraocular hypertension. (drugs.com)
- Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. (uib.no)
- Failing immunological tolerance for critical self-antigens is the problem underlying most chronic inflammatory diseases of humans. (frontiersin.org)
- In many cases, chronic inflammatory diseases are autoimmune diseases that are caused by a loss of tolerance to self-antigens due to inappropriate activation of the immune system. (frontiersin.org)
- However, there is an increasing understanding that pro-inflammatory responses directed to self-antigens become chronic in autoimmune diseases because regulatory mechanisms fail to control them. (frontiersin.org)
- Shelter residents and patients who visited emergency departments reported primarily chronic diseases. (cdc.gov)
- Spinal shock presents usually with a sudden onset (frequently associated with trauma or less likely, vascular lesions), however other non-traumatic lesions could lead to presentations similar to those of spinal shock but may be with a more insidious onset (malignancy, infections, vascular lesions, CNS demyelinating/ degenerative diseases, etc. (clinicaladvisor.com)
- The On The Move study sends three-to-five text messages a week to Latinos ages 45 and older in an effort to prevent diabetes, heart disease, high cholesterol and other chronic diseases. (nbcbayarea.com)
- In line with the observations of the founder of homeopathy, Samuel Hahnemann, epidemic diseases become one of the major founding forces of chronic diseases. (homeopathic.com)
- Realizing this, the authors applied the genus epidemicus principle to chronic diseases such as diabetes and epilepsy: this book documents the results for a wide range of chronic diseases. (homeopathic.com)
- Case studies from around the world demonstrate that disease-specific remedies, combined with individualized prescribing, can greatly improve the results in treating chronic diseases. (homeopathic.com)
- In this study of adults with chronic childhood diseases treated at 30 children's hospitals over a 10-year period, 6 conditions were compared and patient population growth was projected. (aappublications.org)
- Neuroprotective effect of small heat shock protein, Hsp27, after acute and chronic alcohol administration. (nih.gov)
- Small heat shock proteins are able to protect neurons in cerebral ischemia and oxidative stress. (nih.gov)
- In this study, we investigated the neuroprotective effect of small heat shock protein, Hsp27, after acute and chronic ethanol administrations using transgenic mice overexpressing the human Hsp27 protein. (nih.gov)
- Background and Objective: Heat shock protein 70 usually located in the cytoplasm, it plays an important role has a chaperone. (omicsonline.org)
- Saliva and serum samples were evaluated for Heat shock protein 70 by ELIZA Method (Enzyme -linked immunoassay for heat shock protein 70) and statistical analysis was done with independent student't' test. (omicsonline.org)
- Conclusion: Salivary and circulatory Heat Shock protein 70 showed significant increase in Individuals undergoing renal dialysis .Thus, Circulatory and salivary Heat Shock Protein 70 is an efficient stress marker in chronic renal disease condition. (omicsonline.org)
- The presence of a specific group of proteins in the fruitfly Drosophilia melanogaster as a response to high temperature first identified by Ritossa in 1962 then termed as heat shock protein, have been an area of interest with context to their biochemical and functional role, change in cellular changes during disease, aging and infectious process [ 1 ]. (omicsonline.org)
- As a response to stress ancient signalling pathway leads to expression of heat shock proteins, they have an efficient protective mechanism, preventing a non -specific protein aggregate [ 2 ]. (omicsonline.org)
- Heat Shock protein 70 is one of those molecular chaperons which are highly concerned, involved in DE novo folding of proteins also in stressful conditions prevent the aggregation of unfolding proteins and even refold [ 3 ]. (omicsonline.org)
- Heat shock proteins 70 protects cells against oxidative stress inhibits stress kinase and apoptosis [ 4 ]. (omicsonline.org)
- Heat shock protein 70 usually located in the cytoplasm, it plays an important role has a chaperone. (omicsonline.org)
- Members of the heat shock protein 70 (HSP70) family play an important role in assisting protein folding, preventing protein aggregation and transport of proteins across membranes under physiological conditions. (frontiersin.org)
- The heat shock response is activated idiosyncratically in individual cells in a polyglutamine length-dependent fashion. (pnas.org)
- The appearance of misfolded protein has been proposed to be the conserved signal for activation of the heat shock response. (pnas.org)
- The elevated levels of heat shock proteins, also termed molecular chaperones because of their involvement in various steps of protein folding, assist the cell in restoring the protein-folding homeostasis after stress exposure ( 20 , 21 ). (pnas.org)
- Diosgenin restores Aβ-induced axonal degeneration by reducing the expression of heat shock cognate 70. (greenmedinfo.com)
- The Real Housewives of Beverly Hills star Yolanda Hadid reveals how she felt when she was finally diagnosed with severe neurological Lyme disease after previous diagnoses of chronic fatigue syndrome. (doctoroz.com)
- For some chronic fatigue sufferers, yoga brought much-needed relief after they had exhausted conventional medical options. (yogajournal.com)
- Although their symptoms differed somewhat, Dunlap and Klein had two things in common: They were both diagnosed eventually with chronic fatigue syndrome. (yogajournal.com)
- You wouldn't wish chronic fatigue syndrome (CFS) on your worst enemy. (yogajournal.com)
- Chronic fatigue is a diagnosis of exclusion, because there are many other medical problems that have symptoms similar to it,' says Arthur Hartz, M.D., Ph.D., a CFS researcher and professor of family medicine at the Iowa College of Medicine in Iowa City. (yogajournal.com)
- Severe chronic fatigue that lasts six months or longer. (yogajournal.com)
- Those who have fewer than four symptoms but meet all of the other criteria are said to have chronic fatigue, rather than chronic fatigue syndrome. (yogajournal.com)
Spinal Cord I1
- Even though the scenario described above is the most commonly seen, the patient with pure spinal shock secondary to spinal cord injury (SCI) presents with hypotension, normal heart rate or bradycardia, hypothermia, flaccid paralysis, areflexia, loss of sensation, urinary bladder incontinence and intestinal ileus. (clinicaladvisor.com)
- It can often be fixed by giving an electrical shock exactly timed to the heartbeat. (philly.com)
- The electrical shock that John had while awake likely helped create a perfect storm in which the effects of the medication, combined with the adrenaline surge from receiving a shock while he was wide awake, led him to become sick quickly. (philly.com)