Chronic Periodontitis: Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)Periodontal Pocket: An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.Aggressive Periodontitis: Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.Gingival Crevicular Fluid: A fluid occurring in minute amounts in the gingival crevice, believed by some authorities to be an inflammatory exudate and by others to cleanse material from the crevice, containing sticky plasma proteins which improve adhesions of the epithelial attachment, have antimicrobial properties, and exert antibody activity. (From Jablonski, Illustrated Dictionary of Dentistry, 1982)Periodontal Attachment Loss: Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.Dental Scaling: Removal of dental plaque and dental calculus from the surface of a tooth, from the surface of a tooth apical to the gingival margin accumulated in periodontal pockets, or from the surface coronal to the gingival margin.Root Planing: A procedure for smoothing of the roughened root surface or cementum of a tooth after subgingival curettage or scaling, as part of periodontal therapy.Gingival Hemorrhage: The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS, marginal PERIODONTITIS, injury, and ASCORBIC ACID DEFICIENCY.Dental Plaque Index: An index which scores the degree of dental plaque accumulation.Periodontal Index: A numerical rating scale for classifying the periodontal status of a person or population with a single figure which takes into consideration prevalence as well as severity of the condition. It is based upon probe measurement of periodontal pockets and on gingival tissue status.Porphyromonas gingivalis: A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.Gingiva: Oral tissue surrounding and attached to TEETH.Gingivitis: Inflammation of gum tissue (GINGIVA) without loss of connective tissue.Alveolar Bone Loss: Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.Treponema denticola: A species of bacteria in the family SPIROCHAETACEAE, frequently isolated from periodontal pockets (PERIODONTAL POCKET).Dental Plaque: A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.Periodontium: The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Bacteroidaceae Infections: Infections with bacteria of the family BACTEROIDACEAE.Prevotella intermedia: A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium is a common commensal in the gingival crevice and is often isolated from cases of gingivitis and other purulent lesions related to the mouth.Aggregatibacter actinomycetemcomitans: A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.Periapical Periodontitis: Inflammation of the PERIAPICAL TISSUE. It includes general, unspecified, or acute nonsuppurative inflammation. Chronic nonsuppurative inflammation is PERIAPICAL GRANULOMA. Suppurative inflammation is PERIAPICAL ABSCESS.Subgingival Curettage: Removal of degenerated and necrotic epithelium and underlying connective tissue of a periodontal pocket in an effort to convert a chronic ulcerated wound to an acute surgical wound, thereby insuring wound healing and attachment or epithelial adhesion, and shrinkage of the marginal gingiva. The term is sometimes used in connection with smoothing of a root surface or ROOT PLANING. (Jablonski; Illustrated Dictionary of Dentistry, 1982)Benzoylarginine-2-Naphthylamide: An enzyme substrate which permits the measurement of peptide hydrolase activity, e.g. trypsin and thrombin. The enzymes liberate 2-naphthylamine, which is measured by colorimetric procedures.Fusobacterium nucleatum: A species of gram-negative, anaerobic, rod-shaped bacteria isolated from the gingival margin and sulcus and from infections of the upper respiratory tract and pleural cavity.Peri-Implantitis: An inflammatory process with loss of supporting bone in the tissues surrounding functioning DENTAL IMPLANTS.Dental Prophylaxis: Treatment for the prevention of periodontal diseases or other dental diseases by the cleaning of the teeth in the dental office using the procedures of DENTAL SCALING and DENTAL POLISHING. The treatment may include plaque detection, removal of supra- and subgingival plaque and calculus, application of caries-preventing agents, checking of restorations and prostheses and correcting overhanging margins and proximal contours of restorations, and checking for signs of food impaction.Furcation Defects: Conditions in which a bifurcation or trifurcation of the molar tooth root becomes denuded as a result of periodontal disease. It may be followed by tooth mobility, temperature sensitivity, pain, and alveolar bone resorption.Periodontal Diseases: Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Bacteroides: A genus of gram-negative, anaerobic, rod-shaped bacteria. Its organisms are normal inhabitants of the oral, respiratory, intestinal, and urogenital cavities of humans, animals, and insects. Some species may be pathogenic.Campylobacter rectus: A species of CAMPYLOBACTER isolated from cases of human PERIODONTITIS. It is a microaerophile, capable of respiring with OXYGEN.Radiography, Bitewing: Technique involving the passage of X-rays through oral structures to create a film record while a central tab or wing of dental X-ray film is being held between upper and lower teeth.Gingivitis, Necrotizing Ulcerative: An acute or chronic GINGIVITIS characterized by redness and swelling, NECROSIS extending from the interdental papillae along the gingival margins, PAIN; HEMORRHAGE, necrotic odor, and often a pseudomembrane. The condition may extend to the ORAL MUCOSA; TONGUE; PALATE; or PHARYNX. The etiology is somewhat unclear, but may involve a complex of FUSOBACTERIUM NUCLEATUM along with spirochetes BORRELIA or TREPONEMA.Occlusal Adjustment: Selective grinding of occlusal surfaces of the teeth in an effort to eliminate premature contacts and occlusal interferences; to establish optimal masticatory effectiveness, stable occlusal relationships, direction of main occlusal forces, and efficient multidirectional patterns, to improve functional relations and to induce physiologic stimulation of the masticatory system; to eliminate occlusal trauma; to eliminate abnormal muscle tension; to aid in the stabilization of orthodontic results; to treat periodontal and temporomandibular joint problems; and in restorative procedures. (From Jablonski, Dictionary of Dentistry, 1992)Actinobacillus Infections: Infections with bacteria of the genus ACTINOBACILLUS.Eikenella corrodens: Gram-negative bacteria isolated from infections of the respiratory and intestinal tracts and from the buccal cavity, intestinal tract, and urogenital tract. They are probably part of the normal flora of man and animals.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Gingival Recession: Exposure of the root surface when the edge of the gum (GINGIVA) moves apically away from the crown of the tooth. This is common with advancing age, vigorous tooth brushing, diseases, or tissue loss of the gingiva, the PERIODONTAL LIGAMENT and the supporting bone (ALVEOLAR PROCESS).Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Mouth Mucosa: Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.Bacterial Load: Measurable quantity of bacteria in an object, organism, or organism compartment.Mouthwashes: Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed)Gingival Overgrowth: Excessive growth of the gingiva either by an increase in the size of the constituent cells (GINGIVAL HYPERTROPHY) or by an increase in their number (GINGIVAL HYPERPLASIA). (From Jablonski's Dictionary of Dentistry, 1992, p574)Oral Hygiene: The practice of personal hygiene of the mouth. It includes the maintenance of oral cleanliness, tissue tone, and general preservation of oral health.JordanSaliva: The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.Adhesins, Bacterial: Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.Hemagglutinins: Agents that cause agglutination of red blood cells. They include antibodies, blood group antigens, lectins, autoimmune factors, bacterial, viral, or parasitic blood agglutinins, etc.Bacteroidetes: A phylum of bacteria comprised of three classes: Bacteroides, Flavobacteria, and Sphingobacteria.Chlorhexidine: A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.Bacteria, AnaerobicStatistics, Nonparametric: A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)Interleukin-1beta: An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.Cysteine Endopeptidases: ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Biofilms: Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.Root Canal Therapy: A treatment modality in endodontics concerned with the therapy of diseases of the dental pulp. For preparatory procedures, ROOT CANAL PREPARATION is available.

Effect of Porphyromonas gingivalis PrtC on cytokine expression in ECV304 endothelial cells and its level in subgingival plaques from patients with chronic periodontitis. (1/253)

AIM: To investigate the effect of the collagenase gene (prtC) product of Porphyromonas gingivalis on inducing host cells to secrete inflammatory cytokines, and to discuss the correlation between the PrtC level in subgingival plaque samples and clinical parameters. METHODS: A prokaryotic expression system pET32a-prtC-Escheria coli BL21DE3 was constructed. Antigenicity and immunoreactivity of the recombinant PrtC protein (rPrtC) was identified by Western blotting. ELISA was applied to detect interleukin (IL)-1alpha, IL-8, and TNF-alpha levels in supernatants from rPrtC-induced human umbilical vein endothelial cells (HUVEC) originated ECV304 cells. Clinical parameters recorded at baseline and after treatment included bleeding on probing (BOP), probing depth (PD), and attachment loss (AL). ELISA was established to measure the PrtC level in 196 subgingival plaque samples from 49 patients with chronic periodontitis. RESULTS: After coincubation with 1 microg/mL rPrtC for 24 h and with 5 or 10 microg/mL rPrtC for 12 h, the levels of IL-1 alpha, IL-8, and TNF-alpha secreted by the ECV304 cells increased significantly (P<0.05). The PrtC level in the BOP-positive or the > or =5 mm AL or > or = 6 mm PD sites was higher than that in the BOP-negative or the < or =2 mm AL or < or =6 mm PD sites (P<0.05), respectively. Compared with baseline, the PrtC levels in different AL sites or in the < or =6 mm PD pockets decreased remarkably after treatment (P<0.01), but in the BOP-positive or in the > 6 mm PD sites, the PrtC levels changed insignificantly (P>0.05). CONCLUSION: rPrtC is able to directly induce host cells to synthesize and secrete IL-1 alpha, IL-8, and TNF-alpha. The PrtC level in subgingival samples is correlated with BOP, AL, and PD.  (+info)

Transmission of Aggregatibacter actinomycetemcomitans between Brazilian women with severe chronic periodontitis and their children. (2/253)

This study evaluated the transmission of Aggregatibacter actinomycetemcomitans (Aa) in women with severe chronic periodontitis and their children. Thirty women (mean age = 36.1+/-6.0 years) who were mothers of at least one child aged 7 to 16 years were enrolled. In order to investigate mother-child transmission of Aa, the children were also evaluated when their mothers were colonized by the bacterium. Subgingival plaque samples of each woman were collected from 3 sites (mean probing depth of 7.3+/-1.2 mm and mean clinical attachment level of 7.9+/-1.5 mm) and pooled in reduced transport fluid (RTF). These samples were processed, inoculated onto TSBV-agar selective medium and incubated at 37 degrees C in microaerophilic atmosphere for 5 days. Aa was identified on the basis of colony morphology, Gram staining, catalase and oxidase reactions. Aa was found in 8 out of 30 women. Therefore, 8 children from these women (mean age= 12 +/- 3.7 years) were evaluated, but Aa was found only in 2 of them. Aa strains of the two mother-child pairs were evaluated by arbitrarily-primed polymerase chain reaction (AP-PCR), although it was not found similarity between the amplitypes of each pair. No Aa transmission was found between Brazilian women with severe chronic periodontitis and their children.  (+info)

Invasive differences among Porphyromonas gingivalis strains from healthy and diseased periodontal sites. (3/253)

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The broad effects of the functional IL-10 promoter-592 polymorphism: modulation of IL-10, TIMP-3, and OPG expression and their association with periodontal disease outcome. (4/253)

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A double-blind randomized clinical trial of subgingival minocycline for chronic periodontitis. (5/253)

The purpose of this study was to evaluate the presence of A. actinomycetemcomitans, P. gingivalis, P. intermedia, E. corrodens and F. nucleatum in 30 subjects with chronic periodontitis treated by scaling and root planing (SRP) plus minocycline (test group) during 12 months with regular trimester maintenance care. Additionally, we evaluated whether the beneficial effects of the therapy on the microbial flora persisted for 24 months. The test group (n = 15) and the control group [SRP plus placebo (n = 15)] were randomly assigned. After SRP, subjects received minocycline or placebo at the baseline, and at 3, 6, and 9 months at all sites with a periodontal pocket depth (PD) of >or= 6 mm. Moreover, two homologous teeth, initially PD >or= 6 mm, were clinically and microbially monitored by PCR at the baseline, and at 3, 6, 9, 12 and 24 months. Differences in mean PD values between groups were analyzed by Student's t-test (P < 0.05). The results for bacterial frequencies showed no significant differences between groups (Fisher's Exact test, P < 0.05) or between time-points (Friedman test, P < 0.05). We failed to detect any differences between groups related to the presence of target pathogens for 12 months. The effects of both therapies on the microbial flora did not persist for 24 months. The group without supportive periodontal therapy showed an improvement in the pattern of pathogens with either of the therapies.  (+info)

Granulocyte chemotactic protein 2 (gcp-2/cxcl6) complements interleukin-8 in periodontal disease. (6/253)

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Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis. (7/253)

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In vivo determination of multiple indices of periodontal inflammation by optical spectroscopy. (8/253)

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Severe forms of chronic periodontitis affect up to 10% of adults. Tumour necrosis factor and lymphotoxin-alpha genes in the major histocompatibility complex are associated with severe periodontitis. Complement factor C4 is a nearby, polymorphic, functionally relevant gene region. Although associated with chronic mucosal infections, C4 deficiencies have not been assessed in adult periodontitis patients. We tested whether complement levels are systemically altered and C4 deficiencies associated with severe chronic periodontitis. In a case-control study, we analysed levels of plasma C3, and C4, serum classical pathway haemolytic activity, C4 allotypes and C4 gene numbers in 37 patients with severe chronic periodontitis and in 150 voluntary controls. Plasma levels of C3 were higher, and classical pathway haemolytic activity was lower in patients than in controls. Partial C4 gene deficiencies were more frequent in patients than in controls (odds ratio 2.4, 95% confidence interval 1.1-5.5, P = 0.032). ...
This review examines literature data concerning the bacterial findings in chronic periodontitis depending on pocket depth, and presents the latest published information on the presence of proinflammatory factors in periodontal environment. It has been found that chronic periodontitis affects as much …
Eventbrite - The Dental Implant Clinic presents SWHATS - Supportive Periodontal Therapy. An evidence-based approach - Wednesday, 13 September 2017 at The Dental Implant Clinic, Bath, England. Find event and ticket information.
|i|Background/Purpose. |/i|Chronic periodontitis is an inflammatory disease of gums that causes loss of supporting structures of teeth, that is, gingiva, periodontal ligament, cementum, and alveolar bone. Levels of various cytokines in the serum, gingival tissues, and gingival crevicular fluid in patients with chronic periodontitis have been studied, but limited data are available on the level of cytokines in saliva. Therefore, a study was designed to determine levels of salivary IL-6 and IL-17 in patients with calculus associated chronic periodontitis.|i| Materials and Methods.|/i| It was a comparative, cross-sectional study that is comprised of 41 healthy controls and 41 calculus associated chronic periodontitis patients (CP patients). According to the degree of attachment loss, CP patients were subcategorized as mild (CAL 1-2 mm), moderate (CAL 3-4 mm), and severe (CAL > 5 mm) forms of periodontitis. Salivary levels of IL-6 and IL-17 were determined using enzyme-linked
Introduction: Chronic periodontitis (CP) is an infectious disease resulting in the inflammation of the supportive structures of teeth, which leads to loss of attachment and bone, and eventually tooth loss if left untreated. Genetic polymorphisms in the proinflammatory cytokine, interleukin-1 (IL-1A and IL-1B) isoforms have been associated with CP in Caucasians, Asians and Arabs but little is known about their role in Africans. Therefore, the aim of this study was to resolve the association between genetic polymorphisms in IL-1A and IL-1B isoforms and chronic periodontitis in two Kenyan coastal communities, the Taita and the Swahili. Objectives: 1) To determine the association between socio-demographic characteristics, clinical features and CP amongst cases and controls in both ethnic groups. 2) To determine the severity of CP in both ethnic groups. 3) To determine the distribution of interleukin-1 genotype polymorphisms of IL-1Band IL-1A in both ethnic groups. 4) To evaluate the association ...
Methods: Forty chronic periodontitis (CP) subjects with hyperlipidaemia (CP/HPL group), 40 systemically healthy CP subjects (CP group) and 20 systemically and periodontally healthy subjects (control group) were enrolled. The clinical periodontal parameters, the serum concentrations of Lp-PLA2, lipid profiles including total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c) and white blood cell (WBC) counts were determined and compared between different groups. Linear regression analysis was performed to identify the contributing factors of Lp-PLA2 ...
Schätzle, M; Löe, H; Lang, N P; Bürgin, W; Anerud, A; Boysen, H (2004). The clinical course of chronic periodontitis. Journal of Clinical Periodontology, 31(12):1122-1127.. Schätzle, M; Löe, H; Bürgin, W; Anerud, A; Boysen, H; Lang, N P (2003). Clinical course of chronic periodontitis. I. Role of gingivitis. Journal of Clinical Periodontology, 30(10):887-901.. Heitz-Mayfield, L J A; Schätzle, M; Löe, H; Bürgin, W; Anerud, A; Boysen, H; Lang, N P (2003). Clinical course of chronic periodontitis. II. Incidence, characteristics and time of occurrence of the initial periodontal lesion. Journal of Clinical Periodontology, 30(10):902-908.. Schätzle, M; Löe, H; Lang, N P; Heitz-Mayfield, L J A; Bürgin, W; Anerud, A; Boysen, H (2003). Clinical course of chronic periodontitis. III. Patterns, variations and risks of attachment loss. Journal of Clinical Periodontology, 30(10):909-918.. Schätzle, M; Lang, N P; Anerud, A; Boysen, H; Bürgin, W; Löe, H (2001). The influence of margins of ...
This network meta-analysis complements a review undertaken for the American Dental Associations Guideline on nonsurgical treatment of chronic periodontitis
Histopathological Features of Dental Pulp in Teeth with Different Levels of Chronic Periodontitis Severity. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
This study investigated genetic polymorphisms in Interleukin 10 (A-1082G, C-819T and C-592A) in 205 individuals from an admixed Brazilian population. A significantly increased risk of developing chronic periodontitis was observed in individuals with low IL-10 production and Amerindian ancestry. These results suggest that the polymorphisms A-1082G, C-819T, and C-592A, which are associated with ance...
OBJECTIVE The aim of this study was to assess the effect of adjunctive photodynamic therapy (PDT) (using 810 nm diode laser and Indocyanine green as photosensitizer) in chronic periodontitis. MATERIALS AND METHODS Patients with untreated chronic periodontitis were included. Treatment was done according to a split mouth design. All sites received periodontal treatment comprising scaling and root-planing (SRP). Test group were additionally treated with PDT. Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD) and Relative Attachment Level (RAL) were evaluated at baseline, 1 month and 3 months. RESULTS Mean baseline values for PI, GI, PPD and RAL were not different in the test group and control group. Statistical significant difference in PPD and RAL, 3 months after treatment was seen in test group as compared to the control group. CONCLUSIONS In patients with chronic periodontitis, clinical outcomes of conventional SRP can be improved by adjunctive PDT.
T his i nvestigation c ompared g ingival c revicular fl uid (GCF) interleukin-1β (IL-1β) concentrations in periodontitis patients subjected to a strict supragingival biofilm control (Supra) for 6 months. Never-smokers (23) and smokers (n = 20; 19.6 ± 11.8 cigarettes/day) moderate-to-severe chronic periodontitis patients underwent a 6 months period of supragingival control with weekly recall visits. Periodontal probing depth (PPD), bleeding on probing (BOP) and GCF samples (from different PPD category sites: 3-5 mm and 6-10 mm) were obtained at the baseline, 30, and 180 days. IL-1β was assessed by enzyme-linked immunosorbent assay. Generalized estimating equations were used to fit prediction models of IL-1β changes, considering the dependence between the examinations, and using only data from experimental sites. Overall IL-1β concentrations decreased from 3.2 pg/μL to 1.9 pg/μL. Higher baseline IL-1β concentrations were associated with higher baseline PPD values in both groups. There ...
Aim This study evaluated whether diabetes modulates gene expression [interleukin (IL)-1 beta, IL-1ra, IL-6, IL-8, IL-10; tumor necrosis factor (TNF)-alpha; interferon (IFN)-gamma, receptor activator of NF-kappa B ligand (RANKL) and osteoprotegerin (OPG)] in sites with periodontitis. Materials and Methods Gingival biopsies were harvested and divided into three groups - Control group: systemically and periodontally healthy subjects (n = 10); Periodontitis group: systemically healthy subjects diagnosed with chronic periodontitis (n = 20); Diabetes group: type 1 diabetic subjects, diagnosed with chronic periodontitis (n = 20). Total RNA was obtained and analyzed by quantitative polymerase chain reaction. Results Data analysis demonstrated that, except for OPG, mRNA levels for all factors were increased by inflammation (P , 0.001). Interleukin-1 beta, IL-1ra, IL-6, IL-8, IFN-gamma, and RANKL mRNA levels were higher in the diabetic group when compared with the control non-periodontitis group (P , ...
Many studies have looked at the link between periodontitis and heart disease. While there is not enough evidence to say that periodontitis causes hear
OBJECTIVE: To determine the percentage of the blood flow signal that is derived from dental pulp when recording from exposed dentine in a human premolar. DESIGN: Recordings were made from 7 healthy teeth in 5 subjects (aged 22-33 yr.) with a laser Doppler flow meter (Periflux 4001) using either a red (635 nm) or an infrared (780 nm) laser. After exposing dentine above the buccal pulpal horn (cavity diam. 1.6 mm, depth 3 mm) and isolating the crown with opaque rubber dam, blood flow was recorded alternately with infrared or red light from the exposed dentine under four conditions: before and after injecting local anaesthetic (3% Mepivacaine without vasoconstrictor) (LA) over the apex of the root of the tooth; after exposing the pulp by cutting a buccal, class V cavity in the tooth; and after sectioning the coronal pulp transversely through the exposure ...
This multi-center study of the Laser Assisted New Attachment Procedure (LANAP protocol) using the FR Pulsed Nd:YAG laser compared to Scaling and Root Planing alone, Modified Widman Flap (MWF) surgery, and Coronal Debridement (CD) alone will utilize a single-blind, four-quadrant split-mouth design with MWF as the positive control, CD as a weak positive control and SRP as the standard treatment control. The study will be conducted at three (3) to five (5) investigational centers. Subjects will receive the Laser Assisted New Attachment Procedure (LANAP protocol) using the pulsed FR Nd:YAG laser, Scaling and Root Planing alone, Modified Widman Flap surgery, and Coronal Debridement alone each in one quadrant of their mouth at Baseline. Treatment modalities are randomly assigned to quadrants at the time of treatment.. Efficacy evaluations, including clinical attachment level (CAL), probing depth (PD), and bleeding on probing (BOP) will be performed at Baseline, month 6, and month 12 using a Florida ...
BioMed Research International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies covering a wide range of subjects in life sciences and medicine. The journal is divided into 55 subject areas.
Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F., Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-butuner, B., Dias, I., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L-O., Korac, B., Korkmaz, K. S., ...
The University of Melbourne has been working on a vaccine for chronic periodontitis for many years. It looks like they will begin clinical trials in 2018. The vaccine will target enzymes created by the bacteria p.gingivalis and will hopefully reduce the need for surgery or antibiotics to treat severe gum disease. This is especially exciting for patients who are more at risk, … ...
The case shown here is of a 46 year-old female patient diagnosed with a severe generalised Chronic Periodontitis. The x-rays revealed the presence of several angular bony defects, known to progress quickly if left untreated, leading to tooth loss.. ...
How to cite this article: Sahota J, Bakshi D, Kaur G, Singh D, Thakur A, Grover S. Estimation of Plasma Levels of Tumor Necrosis Factor-α, Interleukin-4 and 6 in Patients with Chronic Periodontitis and Type II Diabetes Mellitus. J Contemp Dent Pract 2018; 19 (2):166-169. ...
No.. I was not talking about that small bone like thing above the teethset. I was talking about proper teeth.. see on the left in the xray.. the teeth have lost bone support and appear to be placed in an empty socket! Advanced case of Chronic Periodontitis. Pyorrhoea for the layman. ...
Periodontitis is an endemic inflammatory disease caused by a mixed bacterial biofilm infection that is followed by destruction of tooth supporting tissues. Standard of care consists of lifelong mechanical removal of the biofilm. However, outcome is variable. According to recent EFP and AAP reviews, adjunctive antimicrobial therapy may be beneficial.However, bearing in mind that Colombia has reported the frequent presence of Enterobacteriaceae (Klebsiella and Enterobacter) in subgingival plaque of patients with chronic periodontitis, the response to treatment may be different.The enteric have shown resistance to amoxicillin, amoxicillin / clavulanate, metronidazole and tetracycline in studies conducted in the United States, Norway, Brazil and Colombia.Although the combination ciprofloxacin metronidazole has been recommended in the dental literature are not known publications that demonstrate its effectiveness against periodontopathogens and enteric present in subgingival plaque of subjects with ...
Background and objective:Gingival bleeding reduction in smokers has been associated with decreased blood vessel density. The mechanism of suppressive effect of cigarette smoking on blood vessel density is not precisely defined. The aim of this study was to evaluate the impact of smoking on angiogenesis by assessing mast cells density and VEGF expression in chronic periodontitis. Materials& Methods: 52 paraffin embedded block of gingiva tissues with periodontitis obtained from 30 nonsmokers and 22 smokers undergoing flap surgery were examined immunohistochemically for VEGF expression. Mast cell counts was completed on toluidine blue stained slides. Exposure to cigarette smoking was calculated by the number of packs × year. Patients were classified into 4 groups based on the number of smoked cigarettes. The correlation between VEGF expression and mast cell counts was evaluated and compared in nonsmokers and smokers. Results: The mean number of mast cells (p=0.004) and average value of VEGF expression (p
p,Background: Only a few studies have examined the association between periodontitis and glycated hemoglobin (HbA1c) levels in individuals without diabetes. The aim of this study is to compare HbA1c levels in individuals without diabetes and with and without periodontitis before and after non-surgical periodontal therapy. Methods: This comparative study was done on individuals without diabetes who were 35 to 65 years old. Group A consisted of 30 individuals without periodontitis, and group B consisted of 30 individuals with periodontitis. Body mass indices and clinical parameters, including oral hygiene indexsimplified (OHI-S) score, gingival index (GI), probing depth (PD), clinical attachment level (CAL), and HbA1c level, of all participants were recorded. All participants received non-surgical periodontal therapy (scaling and root planing). After 3 months, all participants were reexamined, and clinical parameters and HbA1c levels were evaluated and compared to baseline values. Results: There ...
Systemic infection and/or inflammation has been related with an increased risk of brain abscesses, cerebrovascular disease, cognitive impairment and other pathological states of the brain. Therefore, it is plausible, that a chronic infection and inflammation disease, such as periodontitis, may affect the central nervous system (CNS). Chronic periodontal disease is a condition that causes breakdown of the supporting tissues of the teeth, alveolar bone and soft tissues. Chronic periodontitis is a multifactorial disease caused by dental plaque composed of pathogenic bacteria that triggers the immune response in susceptible hosts. Oral pathogenic bacteria is a source of chronic infection that can induce local and peripheral production of pro-inflammatory cytokines such as IL-1ß, IL-6 and TNF- , inflammatory mediators, as well as bacterial products such as lipopolysaccaride endotoxin. Viruses, such as herpes and Epstein-Barr, can also be found in periodontal pockets. It is well established that oral ...
lub and colleagues in the 1980s, Golub and others further studied the influence of SDD on the host response on a molecular level.. In 1997, Golub and colleagues26 studied whether SDD administration to a population of patients with chronic periodontitis would reduce the amount of specific collagenases and bone-type collagen degradation fragments in gingival crevicular fluid (GCF). Their study design included SRP in 18 subjects with chronic periodontitis, 12 of which received an adjunctive treatment with 20mg bid doxycycline. Both groups were followed up for a period of two months. A significant reduction in neutrophil-type collagenase (MMP-8) and MMP-13, which is associated with bone resorption, as well as a significant (p,0.05) reduction in collagen degradation fragments, was observed. The authors acknowledged that for the first time, in human studies, a reduction of MMP activity was detected with concomitant reduction in levels of collagen degradation fragments.. In a more recent study Choi et ...
The outstanding performance of XO ODONTOSON 360 and XO ODONTOGAIN scalers was researched and confirmed in numerous scientific publications:. Periodontal treatment:. Drisko CH., Lewis LH. (1996) Ultrasonic instruments and antimicrobial agents in supportive periodontal treatment and retreatment of recurrent or refractory periodontitis. Periodontology 2000 12, 90-115.. Greenstein G. (1999) Povidone-iodines effects and role in the management of periodontal diseases: a review. Journal of Periodontology, 70(11), 1397-405.. Rosling B., Hellström MK., Ramberg P., Socransky SS., Lindhe J. (2001) The use of PVP-iodine as an adjunct to non-surgical treatment of chronic periodontitis. Journal of Clinical Periodontology, 28(11), 1023-31.. Serino, G., Rosling, B., Ramberg, P., Socransky, S. S. & Lindhe, J. (2001) Initial outcome and long-term effect of surgical and non-surgical treatment of advanced periodontal disease. Journal of Clinical Periodontology, 28(10), 910-916.. Slots J., Jorgensen MG. (2000) ...
Chronic periodontitis and DM have close relationship, especially in DM patient with uncontrolled hyperglycemia [13]. In uncontrolled DM patient, periodontitis is more severe in its prevalence and severity [14]. Likewise, periodontitis also affects DM as periodontitis itself can worsen glycemic control of DM patient [15]. Mechanism of this interrelations between periodontitis and DM is still not fully understood, but the receptor activator of nuclear factor-κB (RANK)/RANK ligand/osteoprotegerin axis, receptor for advanced glycation end products pathway and oxidative stress mechanism are reported to be related in recent research [16].. DM is a very frequent metabolic disorder characterized by the presence of chronic hyperglycemia because of low levels of both insulin secretion and its action [14]. T1DM is a type of juvenile diabetes that accounts for more than 85% of all diabetes patients under 20 years of age, accounting for 5%-10% of the worlds DM population. T2DM accounts for 90% of diabetes ...
Amaliya, Timmerman MF, Abbas F, Loos BG, Van der Weijden GA, Van Winkelhoff AJ, et al. Java project on periodontal diseases: the relationship between vitamin C and the severity of periodontitis. J Clin Periodontol. 2007 Apr;34(4):299-304.. Boggess KA; Society for Maternal-Fetal Medicine Publications Committee. Maternal oral health in pregnancy. Obstet Gynecol. 2008 Apr;111(4):976-86.. Eberhard J, Jepsen S, Jervøe-Storm PM, Needleman I, Worthington HV. Full-mouth disinfection for the treatment of adult chronic periodontitis. Cochrane Database Syst Rev. 2008 Jan 23;(1):CD004622.. Eberhard J, Jervøe-Storm PM, Needleman I, Worthington H, Jepsen S. Full-mouth treatment concepts for chronic periodontitis: a systematic review. J Clin Periodontol. 2008 Jul;35(7):591-604. Epub 2008 May 21.. Friedewald VE, Kornman KS, Beck JD, Genco R, Goldfine A, Libby P, et al. The American Journal of Cardiology and Journal of Periodontology Editors Consensus: periodontitis and atherosclerotic cardiovascular disease. ...
We report here that the leptomeningeal cells transduce inflammatory signals from peripheral macrophages to brain-resident microglia in response to Porphyromonas gingivalis (P.g.) LPS. The expression of Toll-like receptor 2 (TLR2), TLR4, TNF- α , and inducible NO synthase was mainly detected in the gingival macrophages of chronic periodontitis patients. In in vitro studies, P.g. LPS induced the secretion of TNF- α and IL-1 β from THP-1 human monocyte-like cell line and RAW264.7 mouse macrophages. Surprisingly, the mean mRNA levels of TNF- α and IL-1 β in leptomeningeal cells after treatment with the conditioned medium from P.g. LPS-stimulated RAW264.7 macrophages were significantly higher than those after treatment with P.g. LPS alone. Furthermore, the mean mRNA levels of TNF- α and IL-1 β in microglia after treatment with the conditioned medium from P.g. LPS-stimulated leptomeningeal cells were significantly higher than those after P.g. LPS alone. These observations suggest that ...
We report here that the leptomeningeal cells transduce inflammatory signals from peripheral macrophages to brain-resident microglia in response to Porphyromonas gingivalis (P.g.) LPS. The expression of Toll-like receptor 2 (TLR2), TLR4, TNF- α , and inducible NO synthase was mainly detected in the gingival macrophages of chronic periodontitis patients. In in vitro studies, P.g. LPS induced the secretion of TNF- α and IL-1 β from THP-1 human monocyte-like cell line and RAW264.7 mouse macrophages. Surprisingly, the mean mRNA levels of TNF- α and IL-1 β in leptomeningeal cells after treatment with the conditioned medium from P.g. LPS-stimulated RAW264.7 macrophages were significantly higher than those after treatment with P.g. LPS alone. Furthermore, the mean mRNA levels of TNF- α and IL-1 β in microglia after treatment with the conditioned medium from P.g. LPS-stimulated leptomeningeal cells were significantly higher than those after P.g. LPS alone. These observations suggest that ...
Periodontitis is a chronic inflammatory disease of tooth supporting tissues resulting in periodontal tissue destruction, which may ultimately lead to tooth loss. The pathogenetic mechanisms of periodontitis are not fully elucidated. The disease is characterized by continuous leukocyte infiltration, likely mediated by local cytokine and chemokine production. There are no serologic biomarkers for the diagnosis of periodontitis, which is based solely on the degree of local tissue destruction. The aim of this study was to identify serological biomarkers for periodontitis by analyzing a spectrum of cytokines in serum from subjects with and without periodontitis and also to investigate if the detected cytokines were expressed by gingival fibroblasts, the most abundant cell type in the inflamed periodontium. We mapped serum cytokine and chemokine levels from periodontitis subjects and healthy controls. We used multivariate partial least squares (PLS) modeling and identified monocyte chemoattractant ...
Platelets from untreated periodontitis patients are hyper-reactive and form more platelet-leukocyte complexes compared to cells from individuals without periodontitis. It is not known whether the improvement of the periodontal condition achievable by therapy has beneficial effects on the platelet function. We aimed to assess the effects of periodontal therapy on platelet reactivity. Patients with periodontitis (n = 25) but unaffected by any other medical condition or medication were included and donated blood before and after periodontal therapy. Reactivity to ADP or oral bacteria was assessed by flow cytometric analysis of membrane markers (binding of PAC-1, P-selectin, CD63) and platelet-leukocyte complex formation. Reactivity values were expressed as ratio between the stimulated and unstimulated sample. Plasma levels of soluble (s) P-selectin were determined by enzyme-linked immunosorbent assay (ELISA). Binding of PAC-1, the expression of P-selectin and CD63 in response to the oral bacterium P.
Periodontitis: Causes, Risk Factors, and Treatment Periodontitis is the inflammation in the teeth and supporting gums. It is a serious gum disease that can result in gum damage and can even destroy the jaw bone. Periodontitis is caused by certain periodontal bacteria in the form of dental plaque. A layer of bacteria and food debris gets build-up on areas that are hard to reach and hence results in periodontitis. Periodontitis always begins with inflammation of the gums commonly called gingivitis. Sometimes it results in bleeding when you brush your teeth. You might notice a discolored bacterial layer on your teeth, if left untreated may result in chronic diseases or tooth loss. Periodontal Treatment: The key to eliminating the periodontitis is by triggering the diseases through diagnosis. As the disease progress, the teeth can be damaged. Hence, it is necessary that the disease should be treated as early as possible. It is important to remove plaque and associated bacteria to resume dental ...
Raghavendra Reddy Nagati, M. Ragul, Nabeeh A. AlQahtani, K. S. Ravi, S. Tikare, Mohan Kumar Pasupuleti. Clinical Effectiveness of Gingival Depigmentation Using Conventional Surgical Scrapping and Diode Laser Technique: A Quasi-Experimental Study. Global Journal of Health Science. 2017; 9(3): 296-303. Nabeeh A. AlQahtani, Betsy J, Angelin D, Baiju, KV. Prevalence of chronic periodontitis and its risk determinants among female patients in Aseer region, Saudi Arabia. J. Taibah Univ. Med. Sci. 2017; 12(3): 241-248.
We found no significant differences in ranges of motion or complications sildenafil ratiopharm kaufen ohne rezept between the 2 groups. The maximum specific rate of product formation was estimated to be 125.7 g total volatile fatty acid/g biomass/day.. chabaudi, hemoglobin digestion occurs in two viagra boots ways: micropinocytosis and cytostomal phagocytosis. The potential for using risk models in future lung cancer screening trials.. Reclaiming wellness-living with bodily problems, as narrated by men with advanced prostate cancer. Age differences in FMRI adaptation for sound identity and location. Responses of semicircular canal and otolith afferents to small angle static head tilts in the gerbil.. Our preliminary results indicate microRNAs should be considered viagra alternatives and evaluated in the etiology of autism. Chorionic villi from first trimester pregnancy terminations showed strong expression of BCL-2 and EGF-R protein. Here we test the hypothesis that TRPC5 is such an additional ...
He said the discovery stage used a German sample with aggressive periodontitis (717 cases vs 4,213 controls) and the CARDIoGRAMplusC4D CAD meta-analysis dataset, which included 60,801 cases and 123,504 controls. Replication was performed in an independent genome-wide association study (GWAS) meta-analysis dataset consisting of patients with either aggressive periodontitis or with chronic periodontitis from Germany, Austria, The Netherlands, and the United States (4,423 cases vs 6,219 controls).. Researchers identified a variant in the promoter region of the gene VAMP8 (a promoter regulates the activity of a gene in response to other stimuli) to be significantly more frequent in CAD and periodontitis cases than in healthy controls, indicating the involvement of this gene in the aetiology of both diseases.. "VAMP8 is of special interest, because it is involved in the import and export of molecules and other substances into and out of the cells (acting as a sort of door)," Dr. Schäfer said. "It is ...
Background: Interpretation of risk for periodontitis is critical for treatment planning. How periodontists assess risk for periodontitis is unclear. Purpose: To study (1) what factors periodontists use when assessing the risks for worsening periodontal conditions anticipating that no treatment would be provided, and (2) if risk assessment is consistent and independent of specialty background training. Material and Methods: Medical history, clinical dental data, full-mouth intra-oral radiographs, and slide pictures were obtained from each of 51 subjects, and the information was provided to 23 examiners. Results: The mean age of the study subjects was 51.5 years (SD±17.7, range 23-81), with 28 women included. In 10 of the subjects, only gingivitis was identified, while 22 subjects had advanced chronic periodontitis. Risk scores assigned for 2 and 4 years differed significantly between European- and US-trained periodontists (p < 0.001) and between graduate students in training and periodontists ...
Material and Method: 10 patients (7 female, 32 to 73 years of age) medicated with cyclosporine and/or calcium channel blocker received oral hygiene instruction, professional tooth cleaning followed by scaling and root planning of all 4 quadrants within 24 hours. Patients rinsed with 0.12% CHX solution and brushed with 1% CHX gel for the next 2 weeks. The clinical situation was re-evaluated approximately 4 months after FMD. After completion of FMD 8 patients were assigned to supportive periodontal therapy (SPT) and monitored for a mean of 24 months. Plaque control record (PCR), gingival bleeding index (GBI), pocket depth (PD) were recorded at baseline, re-evaluation and the last SPT visit. PD sites were stratified as follows: <= 4 mm, 5-6 mm and >= 7 mm ...
Author: press release. The bacteria that cause periodontitis, a disease affecting the tissues surrounding the teeth, seems to play a part also in the onset of pancreatic cancer, say the researchers at the University of Helsinki and the Helsinki University Hospital, Finland, and the Karolinska Institutet, Sweden.. The researchers have investigated the role of bacteria causing periodontitis, an inflammation of the tissues surrounding the teeth, in the development of oral cancers and certain other cancers, as well as the link between periodontitis and cancer mortality on the population level.. The study, published in the British Journal of Cancer, has for the first time proven the existence of a mechanism on the molecular level through which the bacteria associated with periodontitis, Treponema denticola (Td), may also have an effect on the onset of cancer. Researchers found that the primary virulence factor of the Td bacteria, the Td-CTLP proteinase (an enzyme), occurs also in malignant tumors of ...
... How may times have you seen a patient who simply never appears periodontally healthy in spite of all your efforts? It s far too easy to just dismiss this type of patient by rationalizing that this is simply their normal appearance. After all, that is how they always appear: boggy, edematous gingiva with a reddish hue, generalized light to moderate bleeding upon probing, and pockets in the 4-7 mm range. You may have root planed them quadrant by quadrant, tried some antibiotic therapy, put them on a chlorhexidine rinse, and had them return every three months for a prophylaxis. Yet in spite of those efforts, they still appear unhealthy. Welcome to the world of the refractory patient. The term, defined in the AAP s Parameter on Refractory Periodontitis, published in The Journal of Periodontology May Supplement 2000 (Volume 71, No. 71), refers to destructive periodontal diseases in patients who, when longitudinally monitored, demonstrate additional ...
By Borrell, Luisa N Burt, Brian A; Neighbors, Harold W; Taylor, George W Objectives. We assessed the prevalences of periodontitis by education and income levels among US adults with data from the third National Health and Nutrition Examination Survey. Methods. The study was limited to non-Hispanic Blacks, Mexican Americans, and non- Hispanic Whites 50 years of age or older with a complete periodontal assessment during the dental examination. Results. Blacks with higher education and income levels had a significantly higher prevalence of periodontitis than their White and Mexican-American counterparts. The relationship between income level and periodontitis was modified by race/ethnicity. High-income Blacks exhibited a higher prevalence of periodontitis than did low- income Blacks and high-income Whites. Conclusions. Our findings call attention to the importance of recognizing socioeconomic status-related health differences across racial/ethnic groups within the social, political, and historical ...
In Europe, cirrhosis is responsible for 1-2% of all deaths and is the leading cause of liver transplantation.1,2 Periodontitis is a bacterially induced inflammatory disease that affects the supporting tissues of the teeth, characterised by the deepening of periodontal pockets due to loss of connective tissue attachment and bone. Untreated, periodontitis may result in tooth loss. Periodontitis is prevalent in the adult population, with over 35% having periodontitis and 10-15% having severe forms of the disease.3,4 Several studies have assessed the association between periodontitis and cardiovascular diseases, cirrhosis, chronic kidney disease, diabetes mellitus, and respiratory diseases, and an increasing number of studies have suggested that periodontitis may affect the course of systemic diseases.5 Poor oral health and periodontitis are very frequent in patients with cirrhosis.5 In addition, studies have suggested that periodontitis is involved in the progression of liver diseases, and that it ...
Introduction: Propolis is one of the few natural remedies that have maintained its popularity over a long period of time. It s a natural antibiotic is a resinous substance that honey bees collect from tree buds, sap flow, shrubs and other botanic sources. Propolis is a subject of recent research in dentistry, since there is some evidence that propolis may actively protect against oral disease due to its antimicrobial, anti-inflammatory and host modulatory properties. The present research was undertaken to test the efficacy of propolis as an adjunct to SRP on clinical Parameters and cytokine levels in patients with chronic periodontitis. Methodology: 15 patients diagnosed with chronic generalized periodontitis were included in the study. Two quadrants with maximum number of sites with PPD measuring ≥ 6mm were selected from each patient. The clinical parameters like MGI, BOP, PPD, CAL were recorded for the selected quadrants in all teeth excluding third molars. 3 litre of GCF were collected from ...
Generalized, severe, chronic periodontitis is associated with anemia of chronic disease: a pilot study in urban, Indian males : Periodontitis and anemia ...
Amorim, Adriana Gomes; Gurgel, Bruno C sar de Vasconcelos. - Uso de antibi ticos sist micos adjuntos raspagem e alisamento radicular no tratamento da periodontite cr nica e periodontite agressiva: uma revis o integrativa da literatura / Use of systemic antibiotics as an adjunct to scaling and root planing in the treatment of chronic periodontitis and agressive periodontitis: an integrative review. Periodontia; 26(1):39-482016.tab. ...
|p|Advanced gum disease (periodontitis) has been linked to an increased risk of erectile dysfunction, with men with chronic periodontitis more than twice as likely to suffer from ED.|/p|
ARESTIN ®. ARESTIN ® (minocycline HCl) 1mg Microspheres is a prescription drug that is indicated as an adjunct to scaling and root planing procedures to reduce pocket depth in adult patients with chronic periodontitis. For product information view the Canadian ARESTIN ® monograph on Health Canadas online Drug Product Database: Product Monograph. MSDS. Product Brochure. ...
Studies indicate that the statistics for unknown causes of preterm deliveries is approximately 50%. The relationship between maternal infections and preterm labor, preterm delivery and premature rupture of membranes is being increasingly supported through research and reliable evidence (Lopez, Silva D, Ipinza, Gurtlerrez 2005). There has been numbers of recent studies which deduce that periodontal infections may be among the maternal infections which are associated with adverse pregnancy outcomes such as preterm births (Lopez, Silva D, Ipinza, Gurtlerrez 2005). Trial tests have been carried out to obtain evidence to support this claim where intervention studies have demonstrated a significant reduction of preterm births and low birth weight infants in women with chronic periodontitis who received periodontal theory pre-partum, compared to women who did not receive periodontal intervention (Lopez, Silva D, Ipinza, Gurtlerrez p. 2145 2005). Thus; from these tests, strong evidence shows that ...
Background: Cytokine dysregulation plays an important role in Type 2 Diabetes Mellitus (T2DM) and Chronic Periodontitis (CP) with a commonality in pathogenic me
Treating periodontitis once it occurs can be a complex, debilitating, and frustrating process. If you cherished this posting and you would like to get more facts about https://feathersoundsmiles.com kindly visit the page. The most common practice used to deal with periodontitis is scaling, a method that scrapes tartar and bacteria away from the top layer of the tooth. Root planing, another common technique used to take care of periodontitis, is invasive and painful and needs the smoothing of the outer surfaces of the root of the tooth ...
If you are suffering from signs of periodontitis, make sure to visit your dentist promptly for correct therapy. Throughout your see your dental professional will definitely inquire you about the past from your disease. After that the assessment of your teeth and also periodontals is actually being monitored particularly the shade and also the suppleness. Your dental professional would likewise examine your teeth for looseness and also the fitness from your teeth with each other. Mainly, x-ray is actually requested to know if you are actually suffering from bone tissue loss because of periodontitis. Your dental professional would additionally use a gum penetrating in testing for gum illness ...
If you are actually experiencing signs and symptoms of periodontitis, make certain to visit your dentist instantly for effective treatment. Throughout your browse through your dental practitioner will certainly ask you regarding the history from your disease. Then the evaluation from your pearly whites and gum tissues is being actually monitored specifically the different colors as well as the firmness. Your dentist would additionally check your teeth for looseness and also the exercise from your teeth together. Usually, x-ray is asked for to know if you are actually experiencing bone reduction as a result of periodontitis. Your dental expert would certainly likewise utilize a periodontal probing in screening for gum tissue ailments ...
Methods: The study included 88 subjects assigned to four groups of 22 subjects each, as follows: O+CP+ (patients with obesity and periodontitis); O P+ (patients with normal weight and periodontitis); O+P (periodontally healthy patients with obesity); and the control group consisting of periodontally healthy patients with normal weight (O P ). Serum and salivary samples were obtained a week before the recording of clinical periodontal parameters. Local and systemic TOS and TAS levels were determined biochemically ...
Tuesday, July 26th, 2011 Posted in Dental articles for patients , No Comments ». The treatment of periodontitis, including periodontal treatment, drug treatment of periodontitis, periodontal surgery and other aspects. Periodontal surgery is one of a treatment. Periodontal surgery usually includes the following ... Read more.. ...
Periodontitis can almost always be cured. Dedicated preventive routines, along with supplementation and necessary lifestyle changes, can allow your body to rid itself of the infection. Depending on how advanced the condition is you may need professional treatment ranging from maintenance visits to surgical therapies. In extremely advanced stages of the disease it may be impossible, requiring extraction of the teeth to rid the body of the chronic infection.
Resultados: Se analizaron 202 (56.7%) informes de pacientes con periodontitis crónica, 139 (39.1%) de periodontitis agresiva y 15 (4.2%) de individuos periodontalmente sanos. La presencia de microorganismos inusuales de tipo entérico fue 36% y la prevalencia de levaduras 7% en las personas con periodontitis. No se encontraron diferencias significantes entre los tres diagnósticos clínicos con respecto a la presencia de microorganismos entéricos y levaduras. La mayor prevalencia de organismos entéricos correspondió a los géneros Klebsiella, Enterobacter y a bacilos Gram negativos no fermentadores. Se encontraron asociaciones estadísticamente significativas entre la presencia o ausencia de microorganismos infrecuentes con la de algunos microorganismos periodontopáticos en los individuos con enfermedad periodontal ...
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A multifactorial risk pattern of periodontitis has been recognized, where in addition to host and environmental factors, a pathogenic microbiota plays a primary role. The purpose of the current research was to analyze the prevalence of periodontitis-associated microorganisms in patients with aggressive periodontitis and periodontally healthy elders by using molecular-biologic detection methods like eubacterial PCR-amplification of 16S rDNA in combination with dot-blot hybridization. The oligonucleotide probes for the detection of T. forsythensis, P. gingivalis, A. actinomycetemcomitans, C. rectus, F. nucleatum, Fusobacterium spp., P. intermedia, E. corrodens, V. parvula and C. ochracea were designed and evaluated. The PCR products of 42 cultivated target and closely related bacteria were used for the optimization of hybridization conditions. For the epidemiological study, subgingival plaque was sampled from four pockets and one healthy site of 45 aggressive periodontitis patients as well as from ...
Laser-assisted dentistry is a recent emerging trend. Dental lasers are frequently used in oral surgical procedures as well as restorative dentistry and prosthodontics. Er,Cr:YSGG lasers have been used since the last decade in dentistry and reported to have provided better periodontal tissue regeneration than that of conventional non-surgical periodontal therapy [5, 6]. Kelbauskiene et al. [5]. reported that a combination of Er,Cr:YSGG laser and conventional scaling and root plaining had better results compared to scaling root-plaining alone in terms of attachment level restoration. Other types of high intensity lasers such as Er:YAG and Nd:YAG lasers have been recently used in a way similar to Er,Cr:YSGG in the periodontal therapy [22, 23]. Er:YAG lasers are securely used as an alternative to non-surgical periodontal therapy or as an adjunct for pocket treatment [24, 25]. However, there is few evidence showing the superiority of ER:YAG lasers to others [23]. Quadri et al. [26] reported that SRP ...
Periodontal diseases are complex inflammatory diseases and affect up to 20% of the worldwide population. An unbalanced reaction of the immune system toward microbial pathogens is considered as the key factor in the development of periodontitis. Defensins have a strong antimicrobial function and are important contributors of the immune system toward maintaining health. Here, we present the first systematic association study of DEFB1. Using a haplotype-tagging single nucleotide polymorphism (SNP) approach, including described promoter SNPs of DEFB1, we investigated the associations of the selected variants in a large population (N=1337 cases and 2887 ethnically matched controls). The 3′ untranslated region SNP, rs1047031, showed the most significant association signal for homozygous carriers of the rare A allele (P=0.002) with an increased genetic risk of 1.3 (95% confidence interval: 1.11-1.57). The association was consistent with the specific periodontitis forms: chronic periodontitis (odds ...
It is also becoming more commonly recognized that chronic periodontitis may occur simultaneously with both localized and generalized forms of aggressive periodontitis
Periodontal pathology, also termed gum diseases or periodontal diseases, are diseases involving the periodontium (the tooth supporting structures, i.e. the gums). The periodontium is composed of alveolar bone, periodontal ligament, cementum and gingiva. An internationally agreed classification formulated at the World Workshop in Clinical Periodontics in 1989 divided periodontal diseases into 5 groups: adult periodontitis, early-onset periodontitis, periodontitis associated with systemic disease, necrotizing ulcerative peirodontitis and refactory periodontitis. In 1993 at the 1st European Workshop in Periodontology the earlier classification was simplified and the categories periodontitis associated with systemic disease and refractory periodontitis were dropped. Both of these classification systems were widely used in clinical and research settings. However, they failed to address a gingival disease component, had overlapping categories with unclear classification criteria and over focussed on ...
1. Axelsson P, Nyström B, Lindhe J. The long-term effect of a plaque control program on tooth mortality, caries and periodontal disease in adults. Results after 30 years of maintenance. J Clin Periodontol. 2004:31(9):749-757. 2. Hirschfeld L, Wasserman B. A long-term survey of tooth loss in 600 treated periodontal patients. J Periodontol. 1978:49(5):225-237. 3. Knowles JW, Burgett FG, Nissle RR, et al. Results of periodontal treatment related to pocket depth and attachment level. Eight years. J Periodontol. 1979;50(5):225-233. 4. Lang NP, Tonetti MS. Periodontal risk assessment (PRA) for patients in supportive periodontal therapy (SPT). Oral Health Prev Dent. 2003;1(1):7-16. 5. Axelsson P, Lindhe J. Effect of controlled oral hygiene procedures on caries and periodontal disease in adults. Results after 6 years. J Clin Periodontol. 1981;8(3):239-248. 6. Topoll HH, Lange DE, Horvath G. Profilometric and photomacroscopic studies of the surfaces of dental enamel, dentin, and root cementum after ...
Periodontitis, is an infectious ailment of multifactorial origin, that brings about destruction of bone and surrounding tissues. There are various oral pathogens that may be responsible for the destruction. The host encounters these microbial invasions and their products by the production and release of inflammatory mediators from the cells within the body. Glutathione-S-transferase (GST) are a group of enzymes that utilize glutathione in conditions resulting in oxidative stress. These enzymes play a key role in the detoxifycation of such substance. It aids in preventing damage to important cellular components caused by release of free reactive oxygen species. Ceruloplasmin is a ferroxidase enzyme. It plays a role as an anti-inflammatory agent, by its ability to scavenge free radicals within the body. The present study was targeted at evaluating the levels of Glutathione-S-Transferase (GST) and Ceruloplasmin as diagnostic markers for patients with chronic periodontitis in gingival crevicular fluid (GCF)
Periodontitis is a chronic inflammatory disease characterized by destruction of periodontal tissue ultimately leading to bone destruction and has been associated with other inflammatory diseases, such as atherosclerosis. Attachment loss of periodontal tissue is primarily caused by host cell-derived immune responses against subgingival biofilm. The aim of the present study was to determine the cytokine profile in serum, saliva and gingival crevicular fluid (GCF) patients with periodontitis and healthy controls. We show that periodontitis patients exhibit higher numbers of periodontal pathogens and their immune responses are significantly altered. The levels of IL-6 in saliva and GCF were significantly suppressed, and while CXCL8 was not altered in serum, its expression levels were significantly suppressed in saliva and elevated in GCF. The T-cell-derived cytokine IL-2 did not differ between patients and controls in serum and saliva, but there was a significant suppression in GCF of patients. ...
Smoking has an adverse effect on the progression of periodontitis, and also modifies the response of the patient to periodontal treatment. To determine if quitting smoking can have a positive effect on the response to periodontal therapy, Preshaw et al from the University of Newcastle upon Tyne, United Kingdom, examined periodontal healing in patients who recently stopped smoking.. A total of 49 individuals who both smoked and demonstrated chronic periodontitis was recruited. All patients received counseling to assist them to stop smoking. The approach for each patient was specific to his or her needs and could include advice, nicotine replacement therapy or the prescribing of bupropion (Zyban).. At baseline, periodontal parameters were recorded, and a full series of radiographs (vertical bitewings) was taken. All patients received comprehensive nonsurgical periodontal treatment (oral hygiene instruction and root planning and scaling). The patients were seen monthly for smoking cessation ...
Gum disease is not limited to adults. Periodontitis (inflammation of the supporting tissues of the teeth or also known as the periodontium) can also occur in young people. Periodontal disease can generally be divided into different types including chronic, aggressive and necrotizing periodontal disease; with aggressive periodontitis commonly seen in the younger age group. Continue reading →. ...
The present study was undertaken to assess plasma C-reactive protein levels in pregnant women with and without periodontal disease. The study was designed as a prospective cohort study involving a sample size of 45 pregnant subjects in the age of 20-40 were selected from RavindraNath Tagore Medical College and hospital with gestational age of 2-12 weeks divided into 3 groups : Control group (15 healthy non pregnant female without periodontitis; group A; study group - 15 pregnant females with periodontitis - group B) study group (15 pregnant patients without periodontitis) Group C. Periodontal disease activity was recorded at baseline for all groups using month mirror and UNC-15 periodontal probe and Russells Index was recorded. Samples were taken for estimation of C-reactive protein levels from all groups at 2-12 weeks of gestation. CRP levels were determined using latex-agglutination-test. The results revealed a statistically significant increase in the levels of CRP in pregnant women with ...
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Occurrence of Actinobacillus actinomycetemcomitans in patients with chronic periodontitis, aggressive periodontitis, healthy subjects and children with gingivitis in two cities of the state of São Paulo, Brazil ...
A few methanogens have been previously recovered from periodontitis lesions, yet their repertoire may not be completed. We recovered a previously unreported methanogen species in this situation. A 64-year-old Caucasian woman was diagnosed with chronic, severe generalized periodontitis. In the presence of negative controls, an 18-month culture of periodontal pockets in anaerobe Hungate tube yielded
What are the Common Symptoms of Periodontitis?. Periodontitis usually starts out as gingivitis or inflammation of the gums. Your gums become highly sensitive. They are tender, inflamed, and easily irritated. They tend to bleed during brushing or flossing. Sometimes you notice pus in your gum tissue.. Your teeth are likewise sensitive. You may find it uncomfortable or painful to chew your food.. If you do not address the problem immediately, gingivitis will eventually lead to periodontitis, a more serious and advanced form of gum disease, which destroys the bones and tissues around the teeth.. You may notice your gums pulling away from your teeth. You may also have a problem of malocclusion. Your upper and lower teeth do not fit comfortably together when you bite or chew. Some teeth may become loose. You may find that some of your partial dentures suddenly do not fit well anymore.. You notice that you have persistent bad breath. You also experience a chronic, unexplained unpleasant taste in your ...
... This release is available in German . ...A mutual epidemiological relationship between aggressive periodontitis...The first author Dr Arne Schaefer from the Institute for Clinical Mol...Because it has to be assumed that there is a causal connection between...,Periodontitis,and,myocardial,infarction:,A,shared,genetic,predisposition,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
Gum disease sufferers 70% more likely to get dementia," The Times reports. A Taiwanese study found that people with a 10-year or longer history of chronic periodontitis (CP) had a small but significant increased risk of developing Alzheimers disease (AD).. Gum disease is an umbrella term used to refer to a number of conditions that can affect the gums - ranging from gingivitis, which can cause bleeding gums, to CP, where extensive damage to the gums and underlying bones can lead to tooth loss. This study only looked at CP. A previous study did find a link between gum disease and worsening dementia symptoms. But because the people taking part in the study had already been diagnosed with dementia, the picture was muddled, as it was hard to determine a relationship between cause and effect.. This latest study found that people who had CP for at least 10 years had an estimated 70% higher risk of developing AD than people without CP. However, although this increase was judged to be statistically ...
Six solid substrates were compared for suitability to support growth of spirochetes from 18 subgingival plaque samples in patients with advanced marginal periodontitis. The following substrates with rabbit serum were tested: BHIA-SC + blood, RGCA-SC
Almost half of adults living in the U.S. age 30 and over have periodontal disease, according to a recent study by researchers from the Centers for Disease Control and Prevention (CDC). The study, published in the Journal of Dental Research, estimates that over 47% of adults, representing 64.7 million adults, had periodontitis-38% of the adult population age 30 and older and 64% of adults age 65 and older had either moderate or severe periodontitis.
Dr. Pamela Cain of Todays Dentistry in Knoxville, TN, places an emphasis on maintaining healthy gums for good dental health and offers periodontal therapy.
Gingivitis, a common and mild form of gum disease can progress to periodontitis, a more serious infection that damages the soft tissue of the gums and sometimes even destroys the bone supporting the teeth. An international team of researchers and clinicians has charted the microbial ecology of the mouth at all stages of this progression, in nearly 1,000 women in Malawi. This work is laying a foundation of knowledge that could lead to better oral health.
Gingivitis, a common and mild form of gum disease can progress to periodontitis, a more serious infection that damages the soft tissue of the gums and sometimes even destroys the bone supporting the teeth.
Gingivitis/periodontitis answers are found in the Johns Hopkins ABX Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
oral bacteria may be linked to heart disease, arterial blockages and stroke. People with diabetes often have periodontal disease. In addition, there is evidence people with diabetes are more likely to develop and have more severe periodontitis than those without diabetes. Some studies suggest periodontitis can make it more difficult for people with diabetes to control their blood sugar. Given the potential link between periodontitis and systemic health problems, prevention is an important step in maintaining overall health and brushing and flossing alone isnt enough ...
Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue in the periodontal region. Although dysbiosis of the local microbial community initiates local inflammation, over-activation of the host immune response directly activates osteoclastic activity and alveol …
San Francisco, CA (Vocus/PRWEB) February 02, 2011 -- People with severe gum disease (periodontitis) used to have to undergo surgery with a scalpel that
Health, ...PHILADELPHIA Periodontitis a form of chronic gum disease that affect...By blocking a molecular receptor that bacteria normally target to caus...The study published in the Journal of Immunology was led by T...In previous research Hajishengallis Lambris and colleagues showed th...,Penn-led,research,suggests,a,new,strategy,to,prevent,or,halt,periodontal,disease,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
... is the dental clinic in Leeds, UK, specialised in the non surgical treatment of pyorrhoea.
Advanced gum disease, also called periodontitis, is caused by bacterial infection that damages the soft tissue and bone that supports the teeth. According to researchers, a sign of severe periodontitis - had an 80 per cent increase in risk of developing colon cancer.
Philips Oral Healthcare products are designed to aid in the prevention of cavities, plaque and gingivitis. They have not been cleared or approved for the prevention or treatment of periodontitis or other diseases. Emerging research shows that there is an association between periodontitis and certain systemic diseases. A cause and effect relationship has not been established. ...
Furthermore, our group re ported that AMZ shortens the duration of treatment method for aggressive periodontitis. Apart from our re ports, many groups showed A
So I had gum disease when I was like 16 or something. I didnt understand how serious this problem is until I turned 24. It was a nightmare. My teeth had pockets of between 5mm-8mm. Well, thats obviou...
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Obligate anaerobic, mesophilic, asaccharolytic and opportunistic pathogen with a typical occurrence in the oral cavity, involved in dental and oral infections like periodontitis, inflammations and abscesses ...
Periodontitis is an inflammatory response to the commensal oral bacterial flora and represents one of the most prevalent infections in humans. Approximately 90%...
The long-term objectives of this competing renewal are to develop novel therapeutics for periodontitis by inhibiting nuclear factor-kappa B (NF-kB). Periodontit...
Signs of gingivitis and periodontitis (periodontal disease). Healthy gum tissue is characterized by its light pink color. The inter-dental spaces are completely filled and do not bleed when touched. The first signs of gum tissue disease most often are bleeding of the gums and halitosis, the gum tissue is red and swollen. This stage is called gingivitis, which can develop into periodontitis or periodontal disease if left untreated. The signs of periodontitis or periodontal disease are receding gums (gum tissue and bone recedes), longer tooth necks (teeth appear to be longer), damage to the entire periodontium, inflammation of the gums as well as loosening of teeth and in the end loss of teeth. Periodontitis rarely causes pain and the course is often slow and insidious. However, there are some specific forms of this disease that have a very aggressive course. In order to stop periodontitis early on, it is important to take the initial signs very seriously and have them treated by your dentist. ...
Christgau, M., Palitzsch, K.-D., Schmalz, G., Kreiner, U. and Frenzel, S. (1998), Healing response to non-surgical periodontal therapy in patients with diabetes mellitus: clinical, microbiological, and immunologic results. Journal of Clinical Periodontology, 25: 112-124. doi: 10.1111/j.1600-051X.1998.tb02417.x ...
Periodontal treatment, periodontal surgery, Periodontal disease, periodontitis, periodontal pocket, gingivitis, gums disease, santorini dentist, dental clinic santorini
Periodontitis is a chronic inflammatory disease caused by exaggerated host immune responses to dysregulated microbiota in dental biofilms leading to degradation of tissues and alveolar bone loss. Porphyromonas gingivalis is a major periodontal pathogen and expresses several potent virulence factors. Among these factors, arginine and lysine gingipains are of special importance, both for the bacterial survival/proliferation and the pathological outcome. The major aim of this thesis was to develop and test novel methods for diagnosis and prevention of P. gingivalis infection and periodontitis. In study I, anti-P. gingivalis antibodies were developed in vitro for immunodetection of bacteria in clinical samples using a surface plasmon resonance (SPR)-based biosensor. Specific binding of the antibodies to P. gingivalis was demonstrated in samples of patients with periodontitis and the results were validated using real-time PCR and DNA-DNA checkerboard analysis. In study II, we elucidated the ...
Inflammation of the supporting tissues of the teeth characterized by apical migration of the junctional epithelium, loss of periodontal attachment, and loss of alveolar bone. The clinical features include purplish-red swollen (oedematous) and shiny gingival tissue, detachment of the interdental papillae, an increase in the gingival crevice (sulcus) beyond 3mm (periodontal pocket), usually no pain or discomfort, and bleeding on gentle probing. There may also be exudation of pus on digital pressure or probing, tooth mobility, drifting of the teeth, tooth loss, and gingival recession. Subgingival calculus is frequently present and causes additional irritation. The initiation of chronic periodontitis is thought to be due to gene polymorphism, which causes a change in the behaviour of cytokines, substances which influence the immune system. Histologically there is extensive destruction of collagen tissue and there may be fibrosis of the tissue outside the inflamed area. Many bacterial species have ...
Several studies demonstrated that the use of graft material has better clinical results for the treatment of intrabony defects. The purpose of this study is to compare the clinical and radiographic efficacy of alloplast (Biphasic calcium phosphate) and demineralized freeze-dried bone allograft (DFDBA) in treatment of periodontal intraosseous defects. A split mouth study was conducted in 20 subjects diagnosed with chronic periodontitis presenting atleast two intrabony defects in either arch. One quadrant (Site A) received alloplast (Biphasic calcium phosphate) and the contralateral defect (Site B) received DFDBA. The results of study showed that clinically Site B (DFDBA) showed greater reduction in pocket depth and gain in clinical attachment level than site A (Biphasic calcium phosphate), however it was not statistically significant. Site A (Biphasic calcium phosphate) showed slightly more gingival marginal recession than Site B (DFDBA). Radiographically Site B (DFDBA) showed greater bone fill ...
Aggregatibacter actinomycetemcomitans ATCC ® 700685D-5™ Designation: Genomic DNA from Aggregatibacter actinomycetemcomitans strain HK1651 TypeStrain=False Application:
Some prospective studies have observed associations between periodontal disease and breast cancer. Therefore, the aim of the present study was to investigate the composition of the subgingival biofilm of women diagnosed with breast cancer, who also presented with chronic periodontitis. All subjects underwent clinical and microbiological assessment. Subgingival biofilm samples were taken from at least three sites of 44 women who had breast cancer. The mean levels and proportions of 40 bacterial species were determined by checkerboard DNA-DNA hybridization. Spearman correlation was used to assess possible associations between the mean levels of bacterial species and clinical conditions. The five species found at the highest levels were Prevotella nigrescens, Actinomyces gerencseriae, Neisseria mucosa, Porphyromonas gingivalis and Tannerella forsythia. The species detected in the lowest counts were Propionibacterium acnes, Streptococcus constellatus, Streptococcus intermedius, Eubacterium saburreum and
Cobb CM, Low SB, Coluzzi DJ (2010). "Lasers and the treatment of chronic periodontitis". Dent. Clin. North Am. 54 (1): 35-53. ... "Lasers and bacterial reduction: A comprehensive technique to treat chronic periodontitis". Dentistry IQ. Retrieved 28 April ... McCawley, Tom; McCawley, Mark; Rams, Thomas (2018). "Effects of LANAP on Chronic Periodontitis Microbiota". Journal of the ... Laser-assisted new attachment procedure (LANAP) is a surgical therapy for the treatment of periodontitis, intended to work ...
Infection patterns in chronic and aggressive periodontitis. J Clin Perio 2005;32:1055-1061. ... Periodontal pathogens are bacteria that have been shown to significantly contribute to periodontitis. Although approximately ... of species that have been shown to be more closely related to the initial incidence and continued persistence of periodontitis ...
Chronic Periodontitis, and Other Clinical Conditions". Journal of Periodontology. 72 (12): 1790-1800. doi:10.1902/jop.2001.72. ... While some cases of gingivitis never progress to periodontitis,[3] periodontitis is always preceded by gingivitis.[4] ... A dental hygienist or dentist will also look for signs of periodontitis using X-rays or periodontal probing as well as other ... Ammons, WF; Schectman, LR; Page, RC (1972). "Host tissue response in chronic periodontal disease. 1. The normal periodontium ...
Otomo-Corgel J, Pucher JJ, Rethman MP & Reynolds MA (2012). "State of the science: Chronic periodontitis and systemic health". ... Frank Billings (1912). "Chronic focal infections and their etiologic relations to arthritis and nephritis". Archives of ... Focal infection theory is the historical concept that many chronic diseases, including systemic and common ones, are caused by ... Meanwhile, by way of continuing case reports claiming cures of chronic diseases like arthritis after extraction of infected or ...
Chai L, Song YQ, Zee KY, Leung WK (2010). "SNPs of Fc-gamma receptor genes and chronic periodontitis". J. Dent. Res. 89 (7): ...
It is also suspected to be involved in chronic periodontitis. Less frequently, A. actinomycetemcomitans is associated with non- ... Its role in aggressive periodontitis was first discovered by Danish-born periodontist Jørgen Slots, a professor of dentistry ... Although it has been found more frequently in localized aggressive periodontitis, prevalence in any population is rather high. ... Slots J (January 1976). "The predominant cultivable organisms in juvenile periodontitis". Scand J Dent Res. 84 (1): 1-10. doi: ...
"Full-mouth disinfection for the treatment of adult chronic periodontitis". Cochrane Database of Systematic Reviews (1). doi: ... Full mouth disinfection typically refers to an intense course of treatment for periodontitis typically involving scaling and ...
Chronic Periodontitis, and Other Clinical Conditions". Journal of Periodontology. 72 (12): 1790-1800. doi:10.1902/jop.2001.72. ... While some cases of gingivitis never progress to periodontitis, data indicates that periodontitis is always preceded by ... Periodontitis can ultimately lead to tooth loss. The term means "inflammation of the gum tissue". The symptoms of gingivitis ... Recurrence of gingivitis Periodontitis Infection or abscess of the gingiva or the jaw bones Trench mouth (bacterial infection ...
Another cause is due to untreated necrotic pulp (chronic apical periodontitis). It is also the result of inadequate debridement ...
... pathogenesis of periodontal inflammation in chronic periodontitis; the interrelationship between periodontal inflammation and ... chronic systemic inflammatory disorders, such as atherosclerosis; and clinical research in oral implantology. The department of ...
"Porphyromonas endodontalis in chronic periodontitis: a clinical and microbiological cross-sectional study". Journal of Oral ...
"Prevalence and quantification of the uncommon Archaea phylotype Thermoplasmata in chronic periodontitis". Archives of Oral ...
"Periodontal therapy for the management of cardiovascular disease in patients with chronic periodontitis". The Cochrane Database ... It is unclear whether or not dental care in those with periodontitis affects their risk of cardiovascular disease. A diet high ... Obesity and diabetes mellitus are often linked to cardiovascular disease, as are a history of chronic kidney disease and ...
It is implicated as a pathogen in chronic periodontitis which can induce bone loss. This motile bacillus is a gram negative, ...
2004). "Single nucleotide polymorphisms associated with aggressive periodontitis and severe chronic periodontitis in Japanese ...
It is implicated as a pathogen in chronic periodontitis which can induce bone loss. This motile bacillus is a spirochaete.. ...
... is approved for the treatment of chronic periodontitis, gingivitis, endodontics, and peri-implantitis disease. It is ...
Zhang, Yu (May 6, 2016). "A novel species of torque teno mini virus (TTMV) in gingival tissue from chronic periodontitis ...
COPD Chronic periodontitis Pancreatitis Several ocular disorders: keratoconus, retinal detachment, age-related macular ...
There is both an acute and chronic form of this condition. Acute apical periodontitis features include moderate to severe pain ... A chronic apical abscess can be asymptomatic as the pressure from the inflammation is being drained through a sinus tract; a ... Apical periodontitis is a term used to describe acute inflammation of the periodontal ligament surrounding the tooth. This can ... The chronic form of the condition can be asymptomatic but may also include pain from surrounding tissues when stimulated. ...
... is a Gram positive member of the oral flora of some patients with chronic periodontitis. It has been ...
... chronic periodontitis and vitamin D. His book Megahealth was a selection of the Literary Guild, Doubleday Book Club and ... "Vitamin D deficiency may contribute to the explanation of the link between chronic periodontitis and erectile dysfunction". J ...
P. gingivalis is a "red" bacterium and a "keystone" bacterium in the onset of chronic adult periodontitis. Though it is found ... This leads to periodontitis through the disruption of the host tissue homeostasis and adaptive immune response. After using ... The role of P. gingivalis as a community activist in periodontitis is seen in specific pathogen-free mouse models of ... Collagen degradation observed in chronic periodontal disease results in part from the collagenase enzymes of this species. It ...
Other forms of NUG may be chronic or recurrent. Necrotizing ulcerative periodontitis (NUP) is where the infection leads to ... The often severe gingival pain that characterizes ANUG distinguishes it from the more common chronic periodontitis which is ... and chronic periodontitis. Jean Hyacinthe Vincent, a French physician working at the Paris Pasteur Institute describes a ... periodontitis (NP or NUP) is classified as a necrotizing periodontal disease, one of the seven general types of periodontitis. ...
... testing and outcomes of full-mouth scaling and root planing with or without amoxicillin/metronidazole in chronic periodontitis ...
In periodontitis, however, the chemical mediators, or by-products, of chronic inflammation stimulate the osteoclasts, causing ... Jul 2016). "Evidence-based clinical practice guideline on the nonsurgical treatment of chronic periodontitis by means of ... should be considered as the initial treatment for patients with chronic periodontitis. They note that "the strength of the ... Left untreated, chronic inflammation of the gums and supporting tissue can raise a person's risk of heart disease. Prior to ...
This condition can develop into necrotizing ulcerative periodontitis. This is an uncommon form of chronic (more than one month ... This refers to a group of rare syndromes characterized by chronic candidal lesions on the skin, in the mouth and on other ... Chronic erythematous candidiasis is more usually associated with denture wearing (see denture-related stomatitis). This variant ... However, sometimes it can be chronic and intermittent, even lasting for many years. Chronicity of this subtype generally occurs ...
... is a Gram positive anaerobic coccus which is frequently isolated from dental plaque in patients with chronic periodontitis. It ...
Chronic Apical Periodontitis, also known as chronic apical periodontitis nos, is related to periodontitis and polyembryoma. An ... Diseases in the Acute Apical Periodontitis family:. Chronic Apical Periodontitis Diseases related to Chronic Apical ... MalaCards integrated aliases for Chronic Apical Periodontitis:. Name: Chronic Apical Periodontitis 12 14 69 ... Drugs for Chronic Apical Periodontitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):. (show all 9) id. ...
Chronic periodontitis is a common disease of the oral cavity consisting of chronic inflammation of the periodontal tissues that ... September 2009). "Chronic periodontitis and the incidence of head and neck squamous cell carcinoma". Cancer Epidemiol. ... "In patients with chronic periodontitis, subgingival debridement (in conjunction with supragingival plaque control) is an ... Hujoel PP (June 2002). "Does chronic periodontitis cause coronary heart disease? A review of the literature". J Am Dent Assoc. ...
2. The Role of Genetics in Chronic Periodontitis. Evidence for the role of genetic component in chronic (adult) periodontitis ... in aggressive and chronic periodontitis," Journal of Clinical Periodontology, vol. 35, no. 6, pp. 493-500, 2008. View at ... Gene Polymorphisms in Chronic Periodontitis. Marja L. Laine,1 Bruno G. Loos,2 and W. Crielaard1 ... To date, the following IL1 genetic polymorphisms have been studied in association with chronic periodontitis: IL1A 889 (in ...
The chronic inflammatory process of adult periodontitis results in the destruction of supporting osseous and connective tissues ... Profile of cytokine mRNA expression in chronic adult periodontitis.. Roberts FA1, McCaffery KA, Michalek SM. ... In this study, to elucidate the role of these cytokines in chronic adult periodontitis, we tested whether the prevalence of ... This study provides evidence for a major role of TNF-alpha in chronic adult periodontitis. Moreover, our results suggest that ...
... Pin-Chuang Lai and John D. ... non-surgical debridement for the treatment of chronic periodontitis," Journal of Clinical Periodontology, vol. 29, supplement 3 ... "Clinical changes following four different periodontal therapies for the treatment of chronic periodontitis: 1-Year results," ... M. F. Timmerman and G. A. van der Weijden, "Risk factors for periodontitis," International Journal of Dental Hygiene, vol. 4, ...
... were detected in GCF in patients with chronic periodontitis (test group) than patients without chronic periodontitis (control ... Evaluation of non-surgical therapy on glutathione levels in chronic periodontitis.. Palwankar P1, Rana M1, Arora K2, Deepthy C3 ... To compare the levels of glutathione (GSH), both oxidized and reduced forms in patients with and without chronic periodontitis ... The concentrations of GSH within GCF are reduced in chronic periodontitis patients. Scaling and root planing (nonsurgical ...
Diode Laser and SRP in Chronic Periodontitis (PAPD). The safety and scientific validity of this study is the responsibility of ... Periodontitis:Presence of at least two teeth with at least one site with pocket probing depth (PD) ranging from 4 to 10 mm in ... Giannelli M, Materassi F, Fossi T, Lorenzini L, Bani D. Treatment of severe periodontitis with a laser and light-emitting diode ... Photoablative-photodynamic (PAPD) Diode Laser Therapy Adjunctive to Scaling and Root Planing in Periodontitis. ...
While there is not enough evidence to say that periodontitis causes hear ... Many studies have looked at the link between periodontitis and heart disease. ... Advanced gum disease is called periodontitis. It can be very serious. Thats because chronic periodo... ... Continue Learning about Periodontitis. Should I talk to my doctor about my periodontitis symptoms? ...
Chronic periodontitis may be linked to Alzheimers disease. By Theresa Pablos, DrBicuspid.com associate editor. October 29, ... "Periodontitis is a chronic disease, and it takes a long time to develop.". - Keiko Watanabe, DDS, PhD, and colleagues ... She and her team previously discovered that chronic periodontitis could change glucose metabolism in the brain, and they wanted ... "We use animal model systems to mimic chronic periodontitis -- i.e., long exposure to periodontal pathogens or gingival ...
A significantly increased risk of developing chronic periodontitis was observed in individuals with low IL-10 production and ... A significantly increased risk of developing chronic periodontitis was observed in individuals with low IL-10 production and ... chronic << (leukemia,leukaemia) here the word chronic must come somewhere before either the work leukemia or leukaemia.. ... are involved in the susceptibility to the development of chronic periodontitis in an admixed northern Brazilian population. ...
Periodontitis. Chronic Periodontitis. Periodontal Diseases. Mouth Diseases. Stomatognathic Diseases. Moxifloxacin. ... Clinical trial of moxifloxacin in chronic periodontitis Publications: Ardila CM, Fernández N, Guzmán IC. Antimicrobial ... Comparison of Moxifloxacin With Ciprofloxacin/Metronidazole on Patients With Chronic Periodontitis. This study has been ... clinical and radiographic signs of severe (CAL 5 mm or more) chronic periodontitis. ...
Severe forms of chronic periodontitis affect up to 10% of adults. Tumour necrosis factor and lymphotoxin-alpha genes in the ... Although associated with chronic mucosal infections, C4 deficiencies have not been assessed in adult periodontitis patients. We ... C4 gene deficiencies are associated with predisposition to chronic periodontitis.. Place, publisher, year, edition, pages. 2007 ... Complement and c4 null alleles in severe chronic adult periodontitis.. Seppänen, M ...
... chronic periodontitis (odds ratio=2.2 (95% confidence interval: 1.16-4.35), P=0.02), and aggressive periodontitis (odds ratio= ... A 3 UTR transition within DEFB1 is associated with chronic and aggressive periodontitis. Journal. Genes and Immunity. Pages ( ... of the immune system toward microbial pathogens is considered as the key factor in the development of periodontitis. Defensins ... The association was consistent with the specific periodontitis forms: ...
Chronic Periodontitis and Tooth Loss in Patients With Rheumatoid Arthritis. Periodontitis is a highly prevalent chronic ... Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age ... Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people. ... Chronic Periodontitis. Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or ...
Thirty patients with chronic periodontitis were randomly distributed into two groups of 15 patients to receive: SRP or SRP ... IL-1β, TNF-α, total antioxidative status and microbiological findings in chronic periodontitis treated with fluorescence- ... YAG laser versus scaling and root planing as alternative or adjuvant for chronic periodontitis treatment: a systematic review, ... YAG laser application in chronic periodontitis: clinical, immunological, and microbiological aspects, Lasers in Medical Science ...
Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age ... Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people. ... Chronic Periodontitis. Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or ... SRP Alone in Chronic Periodontitis". *Related Companies*Related Events*Related Clinical Trials*Related PubMed Entries*Related ...
Study to Compare Laser Assisted New Attachment Procedure (LANAP) to Traditional Treatments of Chronic Periodontitis (LANAP). ... Subjects will have chronic adult periodontitis as characterized by all four quadrants of the mouth. ... and Coronal Debridement Alone in the Treatment of Chronic Periodontitis. ... Periodontitis causes loss of attachment of the tooth root to the surrounding bone. Change in Clinical Attachment Level (CAL) ...
Effects of Omega-3 Plus Low-dose Aspirin as Adjunct to Periodontal Debridement for Chronic Periodontitis in Diabetics. The ... Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin ...
MCP=moderate chronic periodontitis, SCP=severe chronic periodontitis, OR=oral rinse, GPP=gingival paper point. ... MCP=moderate chronic periodontitis, SCP=severe chronic periodontitis, OR=oral rinse, GPP=gingival paper point. ... MCP=moderate chronic periodontitis, SCP=severe chronic periodontitis, OR=oral rinse, GPP=gingival paper point. ... MCP=moderate chronic periodontitis, SCP=severe chronic periodontitis, OR=oral rinse, GPP=gingival paper point. ...
Effects of Omega-3 Plus Low-dose Aspirin as Adjunct to Periodontal Debridement for Chronic Periodontitis in Diabetics. * ... Acetylsalicylic acid Recruiting Phase N/A Trials for Diabetes Mellitus (DM) / Periodontitis, Chronic Treatment. Back to ...
We previously isolated and characterized two P. gingivalis strains, one from a patient exhibiting severe chronic periodontitis ... We previously isolated and characterized two P. gingivalis strains, one from a patient exhibiting severe chronic periodontitis ... Porphyromonas gingivalis has been extensively associated with both the onset and progression of periodontitis. ... gingivalis has been extensively associated with both the onset and progression of periodontitis. ...
... chronic periodontitis, good oral hygiene, home remedy for periodontitis, periodontitis symptoms, treating periodontitis on ... chronic periodontitis, good oral hygiene, home remedy for periodontitis, periodontitis symptoms, treating periodontitis on ... chronic periodontitis, generalized aggressive periodontitis, Gum Disease, localized aggressive periodontitis, Periodontitis, ... Management of chronic periodontitis. Treating periodontitis can be by the means of:. 1) Control of bacterial plaque - The home ...
... ... Methods: Forty chronic periodontitis (CP) subjects with hyperlipidaemia (CP/HPL group), 40 systemically healthy CP subjects (CP ...
Link Between Periodontitis and Chronic Inflammation. Maintaining healthy teeth and gums is essential if you want to strengthen ... What Is The Link Between Periodontitis and Chronic Inflammation?. Although all the warning signs are essential factors, ... What Is Periodontitis?. Periodontitis is an industry term that a periodontist uses to describe patients that suffer from gum ... For example, the majority of the problems associated with periodontitis are linked with heart disease, diabetes, and arthritis. ...
Chronic periodontitis has been considered to be more common in people aged more than 30, having inadequate oral hygiene (10,11 ... The present study has thus documented determinants of chronic periodontitis in a homogenous study-group in Mexico who often ... Although oral microorganisms seem to play a preponderant role in the aetiology of chronic periodontitis (9), other risk ... Objective Determining the prevalence, severity and extension of chronic periodontitis and identifying risk indicators amongst ...
  • Objective To determine the efficacy of clindamycin compared with amoxicillin-metronidazole after a 7-day regimen during nonsurgical treatment of periodontitis in patients with type 2 diabetes mellitus. (bmj.com)
  • To study the relationship between SUA and hypertension, early nephropathy and progression of chronic kidney disease (CKD) in type 2 diabetes mellitus (T2DM). (pianolarge.cf)
  • Further course of treatment depends on the severity and progression of the periodontitis. (epnet.com)
  • Clinical determinations (probing depth, bleeding on probe, and plaque index) were performed to determine the extent and severity of periodontitis before and after the pharmacological treatment. (bmj.com)
  • The link between obesity and the occurrence and severity of periodontitis is well characterised and obesity constitutes a major risk factor for periodontal tissue destruction, however direct biological evidence is yet to be established. (bham.ac.uk)
  • We are only treating the tip of the iceberg with periodontitis because many people unfortunately think teeth are expendable," Reynolds says. (smh.com.au)
  • Early warning signs include chronic bad breath, tender or painful swollen gums and minor bleeding after brushing or flossing. (hoppedds.com)
  • In research recently published in the journal Applied and Environmental Microbiology, a team of international clinicians and researchers charted the microbial ecology of the mouth during each stage of the progression that occurs when gingivitis develops into periodontitis, in approximately 1,000 women in Malawi where oral infections are very common. (portlandperiodontics.com)
  • levitra images Doxycycline HYC 100 milligram is an antibiotic that is used to treat bacterial infections, such as periodontitis, urinary tract infections, chlamydia, acne and gonorrhea, according to RxList. (nextdayneurontin.com)
  • Periodontitis normally occurs without symptoms. (epnet.com)
  • Chronic anemia is a well-recognized complication of both cancer and cytotoxic treatments and is associated with symptoms (e.g., fatigue, dyspnea) that may induce or exacerbate functional deterioration. (termsreign.tk)
  • It is characterised by a low grade chronic inflammatory state, which contributes to obesity-associated morbidity. (bham.ac.uk)
  • A body of evidence suggests that obesity is associated with periodontitis, and is second only to smoking as a risk factor for periodontal tissue destruction, but underlying biological mechanisms for this association remain unclear. (bham.ac.uk)
  • Since prophylaxis involves a thorough examination of the entire oral cavity, the dentist is able to screen for oral cancer, evaluate the risk of periodontitis and often spot signs of medical problems like diabetes and kidney problems. (colahanandheidelberg.com)
  • Research design and methods In this double-blind, randomized clinical trial, a total of 42 patients with chronic periodontitis and type 2 diabetes were included. (bmj.com)
  • Conclusion The administration during 7 days of clindamycin or amoxicillin/metronidazole showed the same efficacy for the reduction of probing depth, plaque index, and bleeding on probing in patients with periodontitis and type 2 diabetes. (bmj.com)
  • Diabetes mellitus is a risk factor for periodontitis. (bmj.com)
  • By understanding these mechanisms and key molecular drivers, we are looking to pinpoint targetable molecules to reverse this hyper inflammatory phenotype in periodontitis with and without diabetes. (heravilab.com)
  • The complications of chronic periodontitis are the progressive destruction of the periodontal ligament and alveolar bone. (bmj.com)
  • It is so harmful that researchers in Melbourne are poised to start clinical trials into a vaccine to arrest the periodontitis problem plaguing the population. (smh.com.au)
  • Researchers at the centre are working with a biotech company to begin clinical trials into a vaccine for periodontitis after identifying and targeting a destructive keystone pathogenic bacterium, Porphyromonas gingivalis. (smh.com.au)
  • One of the worlds first studies on the effect of medical cannabis in adults suffering from chronic insomnia was conducted at the University of Western Australia in April of 2018. (labroots.com)
  • One in five Australian adults may have a form of periodontitis. (smh.com.au)
  • We've shown in animal models that we can prevent P. gingivalis establishing and producing periodontitis, so we're now scaling up for phase one clinical trials," Reynolds says. (smh.com.au)
  • Blood analysis revealed chronic non-cyclic neutropaenia, monocytosis, and slightly elevated protein levels. (quintessenz.de)