Chromogenic Compounds: Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Sulfur Compounds: Inorganic or organic compounds that contain sulfur as an integral part of the molecule.Cellulose: A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.Cellulase: An endocellulase with specificity for the hydrolysis of 1,4-beta-glucosidic linkages in CELLULOSE, lichenin, and cereal beta-glucans.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Cellulases: A family of glycosidases that hydrolyse crystalline CELLULOSE into soluble sugar molecules. Within this family there are a variety of enzyme subtypes with differing substrate specificities that must work together to bring about complete cellulose hydrolysis. They are found in structures called CELLULOSOMES.PolysaccharidesGlucans: Polysaccharides composed of repeating glucose units. They can consist of branched or unbranched chains in any linkages.Polysaccharides, Bacterial: Polysaccharides found in bacteria and in capsules thereof.Water Microbiology: The presence of bacteria, viruses, and fungi in water. This term is not restricted to pathogenic organisms.Enterobacteriaceae: A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.Water Pollution: Contamination of bodies of water (such as LAKES; RIVERS; SEAS; and GROUNDWATER.)Micropore Filters: A membrane or barrier with micrometer sized pores used for separation purification processes.Sewage: Refuse liquid or waste matter carried off by sewers.Enterobacter: Gram-negative gas-producing rods found in feces of humans and other animals, sewage, soil, water, and dairy products.Tooth: One of a set of bone-like structures in the mouth used for biting and chewing.Tooth Bleaching: The use of a chemical oxidizing agent to whiten TEETH. In some procedures the oxidation process is activated by the use of heat or light.Tooth Discoloration: Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)Tooth Bleaching Agents: Chemicals that are used to oxidize pigments in TEETH and thus effect whitening.Tooth Loss: The failure to retain teeth as a result of disease or injury.Tooth Crown: The upper part of the tooth, which joins the lower part of the tooth (TOOTH ROOT) at the cervix (TOOTH CERVIX) at a line called the cementoenamel junction. The entire surface of the crown is covered with enamel which is thicker at the extremity and becomes progressively thinner toward the cervix. (From Jablonski, Dictionary of Dentistry, 1992, p216)Tooth Abnormalities: Congenital absence of or defects in structures of the teeth.Dental Enamel: A hard thin translucent layer of calcified substance which envelops and protects the dentin of the crown of the tooth. It is the hardest substance in the body and is almost entirely composed of calcium salts. Under the microscope, it is composed of thin rods (enamel prisms) held together by cementing substance, and surrounded by an enamel sheath. (From Jablonski, Dictionary of Dentistry, 1992, p286)Color: The visually perceived property of objects created by absorption or reflection of specific wavelengths of light.Nobel PrizeTryptamines: Decarboxylated monoamine derivatives of TRYPTOPHAN.Opium: The air-dried exudate from the unripe seed capsule of the opium poppy, Papaver somniferum, or its variant, P. album. It contains a number of alkaloids, but only a few - MORPHINE; CODEINE; and PAPAVERINE - have clinical significance. Opium has been used as an analgesic, antitussive, antidiarrheal, and antispasmodic.BenzaldehydesPorphobilinogenCarcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Amino Acids: Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.

Selective delivery of herpes virus vectors to experimental brain tumors using RMP-7. (1/413)

RMP-7, a bradykinin analog, has been shown to selectively open the blood-tumor barrier for the delivery of chemotherapeutic drugs to brain tumors. In contrast to bradykinin, RMP-7 has no hypotensive effects and has been approved for human use. This study was initiated to determine whether RMP-7 would open the blood-tumor barrier to virus vectors encoding tumor-killing genes in an experimental model. The herpes virus vector used, hrR3, which encodes virus thymidine kinase gene and the lacZ reporter gene, is defective in a gene encoding ribonucleotide reductase, replicates selectively in dividing tumor cells and not in postmitotic neural cells. It was determined that an optimum dose of RMP-7 (1.5-3.0 microg/kg over 10-15 minutes) enhanced viral delivery to brain tumors in rats bearing intracranial 9 L gliosarcomas when infused through the carotid artery immediately prior to virus vector application. Maximum expression of the lacZ reporter gene occurred at 3 days after intracarotid infusion. By 8 days, transgene expression was largely confined to tumor foci away from the main tumor mass. Viral delivery was essentially specific to tumor cells, with little transgene expression elsewhere in the brain. Minimal uptake and pathology was noted in the kidney, spleen, and liver. These findings indicate that intracarotid delivery of RMP-7 can augment the selective delivery of virus vectors to brain tumors in an experimental rat model, with the potential for application to human brain tumors.  (+info)

Thermal effects on an enzymatically latent conformation of coagulation factor VIIa. (2/413)

Activation of the zymogen factor VII yields an enzyme form, factor VIIa, with only modest activity. The thermal effect on this low activity of factor VIIa and its enhancement by the cofactor tissue factor was investigated. Factor VIIa activity measured with a chromogenic peptide substrate is characterized by an unusual temperature dependency which indicates that the activated protease exists in an equilibrium between a latent (enzymatically inactive) and an active conformation. As shown by calorimetry and activity measurements the thermal effects on factor VIIa are fully reversible below the denaturation temperature of 58.1 degrees C. A model for factor VIIa has been proposed [Higashi, S., Nishimura, H., Aita, K. & Iwanaga, S. (1994) J. Biol. Chem. 269, 18891-18898] in which the protease is supposed to exist primarily as a latent enzyme form because of the poor incorporation into the protease structure of the N-terminal Ile153 released by proteolytic cleavage during activation of factor VII. Binding of tissue factor to factor VIIa is assumed to shift the equilibrium towards an active conformation in which the N-terminal Ile153 forms a salt bridge with Asp343. We corroborate the validity of this model by: (a) chemical modification of factor VIIa; this suggests that the thermal effect on the equilibrium between the active and inactive conformation is reflected in the relative accessibility of the active site and the N-terminal Ile153; (b) measurements of factor VIIa binding to tissue factor indicating that complex formation is favoured by stabilization of the active conformation; and (c) activity measurements of a cross-linked factor VIIa-tissue factor complex; this showed that cross-linking stabilized the active conformation of factor VIIa and essentially prevented its thermally-induced transformation into the inactive state.  (+info)

Amino acid sequence of trocarin, a prothrombin activator from Tropidechis carinatus venom: its structural similarity to coagulation factor Xa. (3/413)

Among snake venom procoagulant proteins, group II prothrombin activators are functionally similar to blood coagulation factor Xa. We have purified and partially characterized the enzymatic properties of trocarin, the group II prothrombin activator from the venom of the Australian elapid, Tropidechis carinatus (rough-scaled snake). Prothrombin activation by trocarin is enhanced by Ca2+, phospholipids, and factor Va, similar to that by factor Xa. However, its amidolytic activity on peptide substrate S-2222 is significantly lower. We have determined the complete amino acid sequence of trocarin. It is a 46,515-Dalton glycoprotein highly homologous to factor Xa and shares the same domain architecture. The light chain possesses an N-terminal Gla domain containing 11 gamma-carboxyglutamic acid residues, followed by two epidermal growth factor (EGF)-like domains; the heavy chain is a serine proteinase. Both chains are likely glycosylated: the light chain at Ser 52 and the heavy chain at Asn 45. Unlike other types of venom procoagulants, trocarin is the first true structural homologue of a coagulation factor. It clots snake plasma and thus may be similar, if not identical, to snake blood coagulation factor Xa. Unlike blood factor Xa, it is expressed in high quantities and in a nonhepatic tissue, making snake venom the richest source of factor Xa-like proteins. It induces cyanosis and death in mice at 1 mg/kg body weight. Thus, trocarin acts as a toxin in venom and a similar, if not identical, protein plays a critical role in hemostasis.  (+info)

Comparison and recovery of Escherichia coli and thermotolerant coliforms in water with a chromogenic medium incubated at 41 and 44.5 degrees C. (4/413)

This study compared the performance of a commercial chromogenic medium, CHROMagarECC (CECC), and CECC supplemented with sodium pyruvate (CECCP) with the membrane filtration lauryl sulfate-based medium (mLSA) for enumeration of Escherichia coli and non-E. coli thermotolerant coliforms (KEC). To establish that we could recover the maximum KEC and E. coli population, we compared two incubation temperature regimens, 41 and 44.5 degrees C. Statistical analysis by the Fisher test of data did not demonstrate any statistically significant differences (P = 0.05) in the enumeration of E. coli for the different media (CECC and CECCP) and incubation temperatures. Variance analysis of data performed on KEC counts showed significant differences (P = 0.01) between KEC counts at 41 and 44.5 degrees C on both CECC and CECCP. Analysis of variance demonstrated statistically significant differences (P = 0.05) in the enumeration of total thermotolerant coliforms (TTCs) on CECC and CECCP compared with mLSA. Target colonies were confirmed to be E. coli at a rate of 91.5% and KEC of likely fecal origin at a rate of 77.4% when using CECCP incubated at 41 degrees C. The results of this study showed that CECCP agar incubated at 41 degrees C is efficient for the simultaneous enumeration of E. coli and KEC from river and marine waters.  (+info)

Thrombin mutants with altered enzymatic activity have an impaired mitogenic effect on mouse fibroblasts and are inefficient modulators of stellation of rat cortical astrocytes. (5/413)

We produced recombinant human thrombin mutants to investigate the correlation between the thrombin enzyme and mitogenic activity. Single amino acid substitutions were introduced in the catalytic triad (H43N, D99N, S205A, S205T), in the oxy-anion binding site (G203A) and in the anion binding exosite-1 region (R73E). Proteins were produced as prethrombin-2 mutants secreted in the culture medium of DXB11-derived cell lines. All mutants were activated by ecarin to the corresponding thrombin mutants; the enzymatic activity was assayed on a chromogenic substrate and on the procoagulant substrate fibrinogen. Mutations S205A and G203A completely abolished the enzyme activity. Mutations H43N, D99N and S205T dramatically impaired the enzyme activity toward both substrates. The R73E mutation dissociated the amidolytic activity and the clotting activity of the protein. The ability of thrombin mutants to induce proliferation was investigated in NIH3T3 mouse fibroblasts and rat cortical astrocytes. The ability of the thrombin mutants to revert astrocyte stellation was also studied. The mitogenic activity and the effect on the astrocyte stellation of the thrombin mutants correlated with their enzymatic activity. Furthermore the receptor occupancy by the inactive S205A mutant prevented the thrombin effects providing strong evidence that a proteolytically activated receptor is involved in cellular responses to thrombin.  (+info)

Requirement for a different hydrophobic moiety and reliable chromogenic substrate for endo-type glycosylceramidases. (6/413)

A series of synthetic lactosides with aglycones that differed in length and structure were used to determine the substrate specificity of endo-type glycosylceramidases. Endoglycoceramidases (EGCase) from bacteria preferred lactosides with an acylamide structure over simple n-alkyl lactosides. While ceramide glycanase (CGase) from leech did not show preference. N -Acylaminoethyl beta-lactosides and n -alkyl lactosides were substrates for both EGCase and CGase, but N-acylaminobutyl beta-lactosides, whose acylamide residue differs from that in ceramide, were not hydrolyzed by EGCases. Thus, EGCases, but not CGase, appear to require an N-acyl group at the same position as that of intact glycosphingolipid for substrate recognition. A p-nitrophenyl lactoside derivative possessing an N-acyl chain was degraded by both EGCases and CGase and this chromogenic substrate may be an alternative substrate for endo-type glycosylceramidase activity. Km of the chromogenic lactoside for CGase and Rhodococcus EGCase were 28 microM and 2.9 mM, respectively.  (+info)

Ultrastructural localization of light-induced lipid peroxides in the rat retina. (7/413)

PURPOSE: Localization of light-induced lipid peroxides in the rat retina at an ultrastructural level as benzidine-reactive substances. METHODS: Long-Evans rats with nondilated pupils were exposed to intense light of 6000 lux for 12 or 24 hours. Control animals were kept under physiological light conditions. Rats with dilated pupils were exposed to a light intensity of 50 lux or 150,000 lux for 1 hour. For ultrastructural localization the enucleated eyes were fixed in a 0.1-M cacodylate buffer (pH 7.4) containing 2% glutaraldehyde for 2 hours. Pieces of the superior part of the central eyecup were incubated overnight with tetramethylbenzidine (TMB; pH 3.0) at 4 degrees C, postfixed with 1.5% OSO4, and embedded for electron microscopy. RESULTS: In animals exposed to intense light, electron-dense structures appeared exclusively throughout the rod outer segments after an irradiation of 6000 lux for 24 hours or 150,000 lux for 1 hour and were absent in animals with nondilated pupils kept at physiological light conditions. Dilation of the pupils leads to the appearance of electron-dense structures after just 1 hour of 50 lux, whereas rats with nondilated pupils withstand even a 12-hour irradiation with 6000 lux. No electron-dense structures were found when no TMB was used in incubation. CONCLUSIONS: The appearance of electron-dense structures in the rod outer segments depends on the incubation with TMB and intensive light exposure of the rat. Dilation of the pupils lowers the threshold for the emergence of electron-dense structures significantly. This strongly supports the view that light-induced lipid peroxides in the rat retina are localized at an ultrastructural level as benzidine-reactive substances. This protocol presents a tool for the generation and ultrastructural localization of lipid peroxides in rat retinas.  (+info)

Inhibition of rat vascular smooth muscle cell proliferation in vitro and in vivo by recombinant replication-competent herpes simplex virus. (8/413)

BACKGROUND AND PURPOSE: The proliferation of vascular smooth muscle cells (VSMCs) is a common feature associated with vascular proliferative disorders such as atherosclerosis and restenosis after balloon angioplasty. We examined the antiproliferative effects of recombinant replication-competent herpes simplex virus (HSV), hrR3, to proliferative VSMCs both in vitro and in vivo. METHODS: Early passages of Sprague-Dawley rat VSMCs were infected with hrR3 at a low multiplicity of infection (0.01 to 1.0) to examine the in vitro cytotoxic activity of this recombinant HSV to VSMCs in a proliferative state. Sprague-Dawley rats underwent balloon dilatation injury of the left carotid artery to induce neointimal formation. The injured carotid arteries were infected with hrR3 five days after balloon injury. Two weeks after injury, the left carotid arteries were fixed, and the areas of the neointimal and medial layers were analyzed microscopically. Because the reporter Escherichia coli lacZ gene in hrR3 is expressed only in infected cells in which the virus is actively replicating, virus replication was confirmed by X-gal staining. RESULTS: A morphometric analysis revealed that there were significant differences in the intima/media ratio between the HSV-treated group and mock-infected group (0. 354+/-0.068 and 1.08+/-0.055, respectively). In the histological study (X-gal staining), positive X-gal staining was observed chiefly in the VSMCs in the medial layer just beneath the internal elastic lamina, indicating active viral replication. CONCLUSIONS: Virus-mediated cytocidal therapy using recombinant HSV vector is a promising modality for the treatment of the restenosis after balloon angioplasty.  (+info)

Perry, J.D.; Butterworth, L.A.; Nicholson, A.; Appleby, M.R.; Orr, K.E., 2003: Evaluation of a new chromogenic medium, Uriselect 4, for the isolation and identification of urinary tract pathogens
When the target organisms enzyme cleaves the colourless chromogenic conjugate, the chromophore is released. In its unconjugated form, the chromophore exhibits its distinctive colour and, due to reduced solubility, forms a precipitate ...
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BioAssay record AID 416393 submitted by ChEMBL: Inhibition of human MMP1 catalytic domain at 50 uM after 1 hr by fluorescent substrate assay.
Collagenous peptides containing the Ehrlich chromogen (EC) were selectively isolated from a tryptic digest of bovine tendon by coupling to a diazotized polyacrylamide support. The isolated p-phenol-azo-EC peptides were purified and characterized by amino acid and sequence analyses. EC occurred in stoichiometric amounts in trimeric cross-linked chains originating from the known cross-link regions of type-I collagen. The major locus of the EC was alpha 2(I)Hyl-933 x alpha 1(I)Lys(Hyl)-9N x alpha 2(I)Lys(Hyl)-5N but it was also shown to occur at the loci alpha 1(I)Hyl-87 x alpha 1(I)Lys(Hyl)-16C x alpha 1(I)Lys(Hyl)-16C and alpha 1(I)Hyl-930 x alpha 1(I)Lys(Hyl)-9N x alpha 2(I)Lys(Hyl)-5N. After sequence analyses of the C-terminal helical cross-link region alpha 2(I)928-963, corrections are presented for residues 927, 930, 932 and 933 of the bovine alpha 2(I) chain. The collagen-associated EC is postulated to be a trisubstituted pyrrole formed by the reaction of the aldehyde form of a telopeptidyl ...
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You may also wish to search for items by Brauman. 71 matching references were found. Brauman, J.I.; Blair, L.K., Gas phase acidities of amines, J. Am. Chem. Soc., 1971, 93, 3911. [all data] Smyth, K.C.; McIver, R.T.; Brauman, J.I.; Wallace, R.W., Photodetachment of negative ions using a continuously tunable laser and an ICR spectrometer, J. Chem. Phys., 1971, 54, 2758. [all data] Smyth, K.C.; Brauman, J.I., Photodetachment of electrons from phosphide ion the electron affinity of PH2-, J. Chem. Phys., 1972, 56, 1132. [all data] Smyth, K.C.; Brauman, J.I., Photodetachment of electrons from amide and arsenide ions: The electron affinities of NH2 and AsH2., J. Chem. Phys., 1972, 56, 4620. [all data] Smyth, K.C.; Brauman, J.I., Photodetachment of an electron from selenide ion the electron affinity and spin- orbit coupling constant for SeH, J. Chem. Phys., 1972, 56, 5993. [all data] Richardson, J.H.; Stephenson, L.M.; Brauman, J.I., Photodetachment of electrons from large molecular systems: ...
A proton beam radiology system provides cancer treatment and proton radiography. The system includes an accelerator for producing an H.sup.- beam and a laser source for generating a laser beam. A photodetachment module is located proximate the periphery of the accelerator. The photodetachment module combines the H.sup.- beam and laser beam to produce a neutral beam therefrom within a subsection of the H.sup.- beam. The photodetachment module emits the neutral beam along a trajectory defined by the laser beam. The photodetachment module includes a stripping foil which forms a proton beam from the neutral beam. The proton beam is delivered to a conveyance segment which transports the proton beam to a patient treatment station. The photodetachment module further includes a laser scanner which moves the laser beam along a path transverse to the cross-section of the H.sup.- beam in order to form the neutral beam in subsections of the H.sup.- beam. As the scanning laser moves across the H.sup.- beam, it
You may also wish to search for items by Hall, J. and Hall. 15 matching references were found. Celotta, R.J.; Bennett, R.A.; Hall, J.L.; Levine, J.; Siegel, M.W., Electron affinity of O2 by laser photodetachment, Bull. Am. Phys. Soc., 1971, 16, 212. [all data] Celotta, R.J.; Bennett, R.A.; Hall, J.L.; Siegel, M.W.; Levine, J., Molecular photodetachment spectrometry. II. The electron affinity of O2 and the structure of O2-, Phys. Rev. A:, 1972, 6, 631. [all data] Celotta, R.S.; Bennett, R.A.; Hall, J.L., Laser Photodetachment Determination of the Electron Affinities of OH, NH2, NH, SO2, and S2, J. Chem. Phys., 1974, 60, 5, 1740, https://doi.org/10.1063/1.1681268 . [all data] Siegel, M.W.; Celotta, R.J.; Hall, J.L.; Levine, J.; Bennett, R.A., Molecular Photodetachment Spectroscopy. I. The Electron Affinity of Nitric Oxide and the Molecular Constants of NO-, Phys. Rev. A, 1972, 6, 2, 607, https://doi.org/10.1103/PhysRevA.6.607 . [all data] Yan, W.-B.; Hall, J.L.; Stephens, J.W.; Richnow, M.L.; ...
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HardyCHROM ESBL is the only selective and differential chromogenic culture media for the detection of extended spectrum beta lactamase producing organisms.
CA and BiGGY agar are two chromogenic media which allow the presumptive differentiation of yeasts. CA contains various substrates for the enzymes of yeast species. It has been demonstrated that β-N-acetylgalactosaminidase which was produced by C. albicans enables the chromogenic substrates to be incorporated into the medium and the isolates of these species were seen as green colored colonies [16]. BiGGY agar contains bismuth sulphite and the growth on this medium produces brown to black colonies because of the extracellular reduction of bismuth sulphite to bismuth sulphide.. CA is reported to give green colonies of C. albicans and blue colonies of C. tropicalis. In this study 168 of 169 C. albicans isolates grew as distinctive light green colonies on CA, only one isolate was seen as off white colonies. Although we didnt have any C. dubliniensis isolates, differentiation of this species from C. albican s seems to be a problem in CA. Tintelnot et al [17] and Willinger et al [18] reported that ...
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chromogen definition: 1. any substance that can become a pigment or coloring matter, as a substance in organic fluids that forms colored compounds when oxidized, or a compound, not itself a dye, that can become a dye 2. any of certain bacteria that prod...
In the electroacoustic music field, the compositions based on soundscapes or "soundscape compositions" can be characterized by the presence of sound elements from the environment throughout their repertoire. In contrast to sound arts, this is a form of composition in that it uses musical language, rather than the result being a soundscape, it is a composition that uses a sound environment as source material for musical creation, implying a structural strategy for composition. In my PhD thesis, I start with the idea that these compositions, using a very specific logic of sound organization on a poetic-perceptive level, can be distinguished and classified in 3 groups according to morphological criteria applied to the sound mass: 1/ spectral and brilliance flattening, 2/ the distribution, spectral symmetry, and brilliance, 3/inharmonic, amplitude, and brilliance. After characterizing and categorizing a corpus representative of the repertoire [Mancero, Bonardi, and Solomos 2017], I developed ...
The organization has three on-going programs to achieve this mission: Conversations with Brilliance, Brill Talks, and Brill Exchange, which have made a positive impact on more than 54,000 students and families. "Conversations with Brilliance" hosts someone brilliant once every quarter. From international leaders, prize-winning authors and actors, to eminent scientists and business leaders - the "Conversations with Brilliance" series offers a once-in-a-lifetime opportunity with the worlds greatest minds inspiring leadership in Houstons youth and their families. Each speaker will take the audience through his or her life, followed by a question and answer session.. ...
Selective media enable faster results and visual confirmation for the detection, identification, and enumeration of microorganisms
This MasterPieces 24 x 18 550PC Brilliance Puzzle captures the brilliance of life. Fall Frenzy features an exciting frenzy of fall leaves. Temperature, light, and water supply have an influence on the degree and duration of fall leaf color. Low temperatures above freezing promote anthocyanin formation, producing bright red leaves; however, early frost will weaken the brilliant red coloring. Rainy or overcast days tend to increase the intensity of fall colors. To reduce its impact on our environment, the chipboard used in this puzzle is made of recycled material.. ...
Joyce Scott: It was completely unbelievable. She walked in the door like shed come home and she went into the kitchen. There were dirty dishes and she looked at me and laughed and washed up the dishes and then she took her wet hands and wiped them down my body and laughed. She was always doing little tricks. She had a bedroom and she came in and took things out of her suitcase and rolled them up and put them in her dresser and put her shoes under the chair. She was completely at home-like shed been waiting for me to realize she was supposed to be there. I had two daughters at the time and the 10 year old became best friends with Judy. She lived with us for a while and then I found her a board and care home nearby and she stayed there. We saw her every day and shed come spend the weekend with us at our house in the country ...
I thought I had finally won roguelike deck-builder Slay The Spire. In building my Silent deck I focused on card draw and energy production, which allowed me to generate near-infinite loops that, even if ended by a bad draw, generated so much block that nothing could touch me. I was strong as hell. There's a regular enemy in the third act with 999 health, and you don't have to actually beat it, just outlast it, because it dies on its own after a set number of turns. With this deck, I felt confident I could've killed it even without the timer. Nothing could stop me.
Critical to Laminines effectiveness is a naturally occurring co-factor in the PESE called FGF (fibroblast growth factor), which directs primal nutrients to where the body most needs them.FGF nourishes our bodys differentiated and undifferentiated stem cells. FGF is seen as the bridge, or director, for the bodys key nutrients and building blocks. But while it is critical in the development of embryos, including humans-and plentiful in the womb-it is not found to be circulating in human adult bodies. Laminine provides this critical missing link to our health.. All other amino acid supplements created or formulated in nutritional labs are devoid of the FGF director.. FGF is responsible for building the linings in the blood vessels, creating the infrastructure for the nutrients to flow to critical areas of the brain and organs. Research credits FGF with the potential to directly affect many neurological disorders because of its ability to affect the growth of "neurites," signal senders (axons) ...
A roguelike, for those who dont know, is a game that takes after a very old ASCII dungeon crawler called Rogue - the descendants of which mostly share randomized, turn-based, tile-based, permanent death in a brutally difficult package that players spend years mastering. Ending takes much of what makes these roguelikes compelling and vomits out something different - yet familiar - and brilliant.. You guide your @ around the level, one tile at a time - always moving vertically or horizontally. You cant stand still for a turn, nor move diagonally, so you have to watch out that you dont get cornered. Enemies follow simple rules of engagement; they move toward you, crushing you into a pixel paste - complete with a savage *crunch* - at the earliest convenience.. Some only move in one dimension, back and forth along a line, while others must waste a turn on rotating 90 degrees when changing direction. Watch for the ones that look like + signs; theyll grind you down before you know what hit you. ...
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWGs strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
To clarify, Im not talking about those who go to the gym to work out because they want to be healthy. I could be on board with that. I might work out if I had a free gym membership, a cool friend to go with, and cute outfits. Im talking about the people who go above and beyond what is healthy and cross the line into obsession: people who spend so much time in the gym they dont have time for anything else. Those people are motivated by something other than their own health. Clearly, they have a beauty standard in their head that they want to achieve and maintain, and if they have set that standard for themselves, then why wouldnt we expect them to apply it to everyone else? ...
The best theoretical physics blog that the search engine can offer you, by a Czech conservative string theorist, focusing on high-energy physics and the climate change facts
Lisa Granshaw is a freelance writer based in New York City. Her work has appeared on the Daily Dot, TODAY.com, Parents Magazine, The Huffington Post, and more. Follow her on Twitter: @LisaGranshaw.. ...
In a memorable passage in the opening pages of Thomas Manns Death in Venice, an observer says of the eminent writer Gustav von Aschenbach: "…[He] has always lived like this-here the speaker closed the fingers of his left hand to a fist-never like this-and he let his open hand hang relaxed from the back of his chair.". What more appropriate image for the art of criticism: the tightly closed fist, the open and relaxed hand? The one concerned with defining boundaries, passing judgment, inflicting punishment; the other with presenting the subject sympathetically, pushing beyond boundaries, a predilection for appreciation and praise. Contrary to what might be assumed, it is far easier for the critic to revile than to reveal; to deride and dismiss than to illuminate, especially when difficult work is being considered. In ordinary language, to be "critical" means to find fault, justly or unjustly. In fact, is there an art more exacting, more risky, more vulnerable to censure, than the art of ...
I would encourage all to use inspiration as a means of achieving a stress free life of achievement. A person, free of stress chemicals, who is creative, is
His download researchers of software understand affiliated linen light researchers, early and honest creatures, subtest template, and few incident. Timmreck, is an extent print dial and silver of The Timmreck Group in Houston, Texas. She has a race of the Multisource Feedback Forum, a fire of traits with global MSF voices.
Ive sometimes heard people deride young-earth creationists, mythicists, and various others as stupid. But that is grossly unfair. Whether someone is wrong need not and often does not correlate with their intelligence or lack thereof. Indeed, it can require astounding mental acumen to find ways to defend ones
I review the shiny new pre workout from Prime Nutrition. In this Max HP review Ill tell you everything I have learned from my pre workout test with Max HP!
As cliché; as it sounds, one should pursue their interests. If you find something that inspires and motivates you, then dedicate yourself to it. Think abou
The presence of chromogenic substrate gives blue coloured colonies if the plasmid in the bacteria does not have an insert presence of insert results into insertional inactivation of Beta galactosidase and recombinant colonies do not produce any colour these are identified as Recombinant Colony
Poster Portraits from AC Forum 2017 provide practicing anticoagulation professionals the opportunity to share their latest research, best practice approaches, and real world experience in addressing contemporary issues and challenges in anticoagulation., TV Network
Selective differential chromogenic medium for the isolation, enumeration and presumptive identification of L.monocytogenes according to ISO 11290 1/2 AMD1; for use with: ...
The Nutshell Putative Gay Genes Identified, Questioned A genomic interrogation of homosexuality turns up speculative links between genetic elements and sexual orientation, but researchers say the study is too small to be significant. ...
Alhamdulillah.. cuti sem kali ini penuh dengan program2 yang bermanfaat.. takde la rasa panas je dok diam tak buat apa2 waktu cuti.. teringat kata2 dari senior di cfs katanya "cuti 3 hari kat rumah yang dimanfaatkan dengan membantu emak ayah lebih bermanfaat dari cuti seminggu di rumah tak buat ape buat perabih beras, tak payah.." hehe.. lebih kurang begitu lah ayatnye sebab yang paling saya ingat yang perabih beras tu je.. hihi ...
Applying type brilliance places means bringing the inside. black colored stool. Enhance the cottage or bungalow should not have a lot of difficulty following a land utilising the brain and function covering of the subject rests right away from screen.
A technique for identifying a vein in a patient is disclosed. The technique involves the application of a thermochromic ink to a venous area on the skin of a patient (e.g., human or animal). The thermochromic ink comprises thermosensitive color-changing microcapsules that contain a proton-accepting chromogen and a desensitizer. The desensitizer possesses a melting point above which the chromogen is capable of becoming protonated, thereby resulting in a color change. Thereafter, the venous area is observed for the color change.
In a flash of inutterable brilliance it occurs to me to wonder--a week after my doctor prescribed a stool test to explore where I might be experiencing blood loss that might be causing my iron deficiency-if Im losing blood in my urinary tract. I twice have seen visible blood in my unine (before the superpubic); was admitted to and kept in the hospital for two days on the basis of my culture before they decided that though I was colonized I was not infected; my caregiver said she saw blood
In the years since leaving Scientology, Ive become aware of just how brainwashed I had been. I have probed for exactly HOW an intelligent, well-educated, free-thinking agnostic could be so taken in by a religion, which I then did not believe it to be. In discovering this, I could only be awed by Hubbards twisted brilliance. He knew exactly what he was doing. Had he lived in more primitive times, before the mass media (which he feared) and the information superhighway (which his successors fear), he certainly would have succeeded. Should his autocratic cult ever come to great power, he may yet become a God in most minds, as he intended. And I believe the human race would then suffer perhaps the most fascistic, mind-controlling domination in history. What gets one addicted to heroin? Long before any physical addiction, there is the rush, the high, the temporary RELEASE from all suffering - emotional or physical, conscious or not. For perhaps the first time, there is no anxiety, no fear, no ...
Dr. Sarah Colley took to the stage with the subject of Product Management with the brain in mind. A psychologist by trade, Sarah set up a business called Pockets of Brilliance which builds products and this year has helped to achieve 7 national award nominations. She follows 2 mottos - the first being "show, dont tell" and the second being "diagnose well before we prescribe".. She spoke about her top 3 "burn points":. 1.Unpredictable people/lack of control;. 2.Slow processes;. 3.Best practice and the energy to teach.. Sarah stressed the importance of thinking, and from this she pointed out that the brain has a golden rule - it creates habits to conserve energy. The brain accounts for 2% of our body weight, 20% of oxygen, 25% of body energy, runs through 70,000 thoughts per day, and 200,000 to 350,000 actions.. The 2 types of main thinking habits of the brain are Heuristics and Biases.. In psychology, heuristics are simple rules which are often used to make decisions. The Stockdale Paradox ...
Advanced Brightening Serum by EVE LOM at b-glowing. Aiming at a skin glowing with youthful brilliance, this Advanced Brightening Serum rectifies pigmentation problems, enhances brightness of skin, rejuv
The desire for knowledge can be traced in all living beings, in the lower creation as well as in mankind. If one notices the movements of the birds and animals in the forest, one sees that besides seeking for their food, playing with their mates, protecting themselves from their enemy, they are also interested in every sensation that comes to them through their five senses. Sound, color, touch, scent, every sensation, has an effect upon them. One can trace in the animals the natural desire to know something, and it is this desire which in human evolution can be recognized as curiosity. From childhood this tendency seems predominant, and the more a child shows this tendency, the more promising the child is, because that shows that the soul part of the child is so much more to the fore. Among grown-up persons, what strikes us most in their personality is that brilliance of intelligence, apart from all their goodness and virtue. If this is such an important things in life, it must achieve a most ...
The J. William Mullen award is given in memory of past CMG president Bill Mullen. This award recognizes his contributions to CMG and the profession of information technology. The award recipient is an individual who exhibits both technical excellence and an engaging presentation style.. The intent of this award is to reflect the nature of the individual for whom it is named. Bill Mullen was a man of exceptional intellectual brilliance and personal charisma, and was widely known for his excellent technical presentations at many professional conferences throughout the world.. ...
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Remarkably, the lead role of Apolinario Mabini is being played by a woman, Ms. Delphine Buencamino. According to the production notes, this gender-bending casting was borne out of musical necessity, to set Mabinis voice apart from the dominantly male voices in the cast. Yet, secondarily, this casting choice also emphasized Mabini being the ostracized odd-man out. I had seen Buencamino act last year in UP and in Virgin Labfest X. Her role and performance here in "Mabini" should by far be her most challenging and her most memorable. She totally captured Mabinis intellectual brilliance, principled conviction and later, his bitter disillusionment. Beyond the initial adjustment about her feminine and youthful festures, Delphine Buencamino became Mabini. (Coincidentally, Ms. Delphines celebrated mother Shamaine Centenera-Buencamino also did a gender-bending role in Dulaang UPs "Ang Misis Kong Promdi" last year, but only in a supporting role. Daughter trumps mom in this regard.) ...
Yesterday saw the unveiling of "Never Work For Free," the first pre-release track from Tennis upcoming, highly-anticipated album, Ritual In Repeat. Explore new territories and swim into the salty waters of what sounds like analogue synthesizers, alternative guitar tunings and self-reflection. This Denver couple, Alaina Moore and Patrick Riley, never disappoint - and once again, their melodies and lines are newly filled with an invigorating beauty and brilliance.. ...
Here is the official description from the 272 page book :. Eduardo Saverin and Mark Zuckerberg were Harvard undergraduates and best friends-outsiders at a school filled with polished prep-school grads and long-time legacies. They shared both academic brilliance in math and a geeky awkwardness with women. Eduardo figured their ticket to social acceptance-and sexual success-was getting invited to join one of the universitys Final Clubs, a constellation of elite societies that had groomed generations of the most powerful men in the world and ranked on top of the inflexible hierarchy at Harvard. Mark, with less of an interest in what the campus alpha males thought of him, happened to be a computer genius of the first order. Which he used to find a more direct route to social stardom: one lonely night, Mark hacked into the universitys computer system, creating a ratable database of all the female students on campus-and subsequently crashing the universitys servers and nearly getting himself kicked ...
The tall tale comes naturally to our kind. It is a necessary device to preserve the image that we want the world to see. It is a consequence of our belief in our brilliance, attractiveness and omnipotence. Social conditioning means that people rarely challenge deviations from the truth, these white lies oil our interaction with…
Melting down in a pool of stress? Install Lagoon 3D Screensaver and enjoy the quiet splendor of a Caribbean beach with pearly white sand, shimmering water and palms silhouetted against the setting sun. Quiet music adds brilliance to the visuals.
Nokia may be one of the leading cell phone manufacturers in the world, but DozenMobile tells it like it is and has ranked the mobile giants app store Ovi.com as a Flop! So how did this happen? Well, the editors at DozenMobile.com sat down and tested all the mobile apps sites they could find. Then, they selected 12, yes just 12, of the entire mobile apps industry and tested them out by using a range of parameters. After these tests, we found that Ovi.com just couldnt compete with the brilliance of.... ...
Ill have a dopamine chaser, please. With ice and a slice. Oh, actually, make that a double. If youre aware of the brains bio-chemical brilliance, youll know that dopamine is the reward hormone...
Ill have a dopamine chaser, please. With ice and a slice. Oh, actually, make that a double. If youre aware of the brains bio-chemical brilliance, youll know that dopamine is the reward hormone...
5. The film you just watched made you wince, moan and snarl and not because of its brilliance but for the sheer fact that it was allowed to be made at all - just because you put about ten Women together who are stupidly famous and who have all had superb parts in the past does NOT mean that combined they create a good film - utter, utter cringeworthy, cliche-ridden drivel with plastic hairdos and botox at its best... Gah ...
Nineteen Eighty-Four is a rare work that grows more haunting as its futuristic purgatory becomes more real. Published in 1949, the book offers political satirist George Orwells nightmare vision of a totalitarian, bureaucratic world and one poor stiffs attempt to find individuality. The brilliance of the novel is Orwells prescience of modern life--the ubiquity of television, the distortion of the language--and his ability to construct such a thorough version of hell. Required reading for students since it was published, it ranks among the most terrifying novels ever written. ...
Nineteen Eighty-Four is a rare work that grows more haunting as its futuristic purgatory becomes more real. Published in 1949, the book offers political satirist George Orwells nightmare vision of a totalitarian, bureaucratic world and one poor stiffs attempt to find individuality. The brilliance of the novel is Orwells prescience of modern life--the ubiquity of television, the distortion of the language--and his ability to construct such a thorough version of hell. Required reading for students since it was published, it ranks among the most terrifying novels ever written. ...
Two things you need to know about this song: 1) you could give a braindamaged child a crayon and a piece of paper and hed write words with more wit and resonance than "Somebody told me, that you had a boyfriend, who looked like a girlfriend, that I had in February of last year". 2) Its an amazing pop song, in the way all the early Police singles are great pop songs. "This is our most Vegas-influenced song on the album," says singer Brandon Flowers. "Sin city, The Strip. Its where I grew up and it affects the songs I write." Sordid, inane brilliance from Flowers and the other three.. ...
This book (12mo, Cloth. New York: Frederick Warne Co. $1 net) is divided into four parts, viz., Chess Players Mentor, Modern Chess Brilliancies, Guide to Openings, and Games at Odds. It is compiled by F.J. Lee, a well-known professional chess player, who has made numerous trips through Great Britain, and G.H.D. Gossip ...
Toenails brittle, jagged sheets of mica Skin picked at, flaking, valleys of cracked mud Hair falling, lacking luster, crisp October leaves Everything disease, teeth abscessed rotting trees Everythings shed Everythings dead Letting go On its way out Not long for this space Just a bundle of brilliance on a constant crash course of forward motion…
I dream now, woven brilliance in poppy fields. Looking back is not an option. Succulent fauna, new to me, flow through the ravine. These lands are not my domain. I look upon the crest of the...
Sorry for the silence. Were in the throes of our busy season, which lasts until mid-October. This means were working long and wacky hours and often Im just plain too tuckered out to post anything on my blog. My flashes of (cough) brilliance are becoming less frequent as Im getting spread thin ...
Collins seemed reluctantly to acknowledge that it often comes down to people. If Amgen had not happened to snag Fu-Kuen Lin (who just happened to catch an ad in the paper), it probably wouldnt have developed the drug that made it boom. Without Bill Gates, Microsoft wouldnt have happened. Amid all the luck, good and bad, they finally seem to admit something I dont think they wanted to--the brilliance of specific people has often been the ultimate key ...
A page for describing Fridge: Corpse Bride. Fridge Brilliance Social Class Distinctions: The contrast between the World of the Living and the World of the …
The Komen controversy showed the brilliance of secondary boycotts-and the injustice of punishing unions for using the same tactics. The following article first appeared at Working In These Times, the labor blog of In These Times magazine. For more news and analysis like this, sign up to receive In These Times weekly updates.
A page for describing Fridge: Jeeves and Wooster. Fridge Brilliance The fact that Aunt Agatha sounds like antagonist. By that same logic: agony. A …
A little film called Gigantic came out a few years ago to little fanfare, earned little acclaim, then exited into the wings. Which is really too bad, because while it overreaches occasionally, somehow hitting too subtle and too obvious at the same time, its writing---especially the dialogue---is incredible. Much of its brilliance probably has to…
For all the flashes of brilliance in the long history of the Transformers, there are some ideas that seem so utterly half-baked it is a wonder that anyone of authority ever green-lighted their manufacture. I say half-baked because the theory itself is sound: have a single robot mode with multiple, simultaneous alt modes. Magmatron proved…
The best place to get reviews on current comics, classic films, world news, new music and the occasional work of prose, written by Tucker Stone, Nina Stone & Marty Brown. Full of lists of albums and brilliance.
More than any event in recent times, our reaction to the death of George Best has left me feeling depressed. I felt sorry for my children and their children yet unborn that they should live in a country that celebrates the death of a flawed footballer as though he were a great statesman or a writer of towering brilliance.
Enzyme Acceptor: 2.5 mg lyophilized powderEnzyme Donor: 0.25 mg lyophilized powderEnzyme Donor Stabilization Buffer: 25 mLEnzyme Acceptor Stabilization Buffer: 25 mLBeta-galactosidase Chromogenic Substrate: 25 mgBeta-galactosidase Chromogenic Substrate Buffer: 25 ...
im back..setelah seminggu bercuti balik kg, arini dah start keje balik..penat badan masih terasa..dlm hati rasa mau je smbung cuti tp bila fikirkan cuti pun dah xbyk maka gagahkan diri gakla keje arini..eniwey byk cerita nk cerita maklumla kata cuti seminggu kan???tp gambar2 masih dlm kamera so xleh update lagi..nti sy stori mori ek..now nk intai2 bos besar n bos kecik, nk check line sbb rasa2nya mata ni xleh tahan sgt dah..mau zzzzZZZZZzzzzzzzzzz...tadaaa.. ...
Which are Catalase (+)?|-Staph Aureus-Pseudomonas Aeruginosa-Candida-Aspergillus-Enterobacteriacea esp KlebsWhich have a pigment production?What color?|-Pseudo aerugi(Bluegreen,fluoroscein)-Serratia(Red)-Staph Aureus(Yellow)-Mycobacteria(Yellow/Orange)-Coryne Diph (black to Gray)
The storm continues. Hubs has staph aureus and they cant find the source of infection. It seemed yesterday that he was improving, but I called him...
Tetraphase Pharmaceuticals, Inc. (NASDAQ:TTPH) today announced initiation of patient enrollment in the pivotal portion of its IGNITE 2 Phase 3 clinica
Joullié's lab has developed compounds with enhanced chromogenic and fluorogenic properties, useful in fingerprinting and ... Early in her career, her Ph.D. advisor, Allan R. Day, interested her in heterocyclic compounds, and she did early work with ... Joullié's specialized compounds made Folkman's original treatments 100 to 1000 times more potent. Beta-cyclodextrin sulfate is ... Joullié, with students Olga Petrovskaia and Diane Hauze, developed and patented a class of compounds called indanediones. Like ...
These chromogenic compounds are modified to change color or fluorescence by the addition of either enzymes or specific ... One technique for detecting indicator organisms is the use of chromogenic compounds, which are added to conventional or newly ...
Metallic compounds. Exposure to such metallic compounds may be in the form of medication or occupational exposure. Examples ... Tannin is also present in coffee, tea, and red wine and produces a chromogenic agent that can discolor teeth.[15] Large ... Coloured compounds from these sources are adsorbed into acquired dental pellicle or directly onto the surface of the tooth ... As enamel wears down, dentine becomes more apparent and chromogenic agents are penetrated in the tooth more easily. The natural ...
... (AEC) is a chemical compound commonly used as a chromogenic substrate in immunohistochemistry, ... After the chromogenic oxidation reaction catalyzed by HRP, a red water-insoluble precipitate is formed in situ, visualizing the ...
These compounds do not react in reducing sugar assays but their hydrolysis products do. This makes borohydride reduced cello- ... Soluble chromogenic substrates: A cellulase sample is incubated with a water-soluble substrate such as azo-CM-cellulose, the ... McCleary, BV (Nov 1980). "New chromogenic substrates for the assay of alpha-amylase and (1 leads to 4)-beta-D-glucanase". ... These substrates can be subdivided into two classes- Insoluble chromogenic substrates: An insoluble cellulase substrate such as ...
... biochemicals can often be converted to colored compounds suitable for chromogenic color-forming reactions to yield compounds ... Scientists use this instrument to measure the amount of compounds in a sample. If the compound is more concentrated more light ... "Hewlett Packard: Compound Identification with HP 8450 A UV Visible Spectrophotometer". Analytical Chemistry. 51 (12): 1188A- ... Qualitative analysis can be used and spectrophotometers are used to record spectra of compounds by scanning broad wavelength ...
... biochemicals can often be converted to colored compounds suitable for chromogenic color-forming reactions to yield compounds ... Scientists use this instrument to measure the amount of compounds in a sample. If the compound is more concentrated more light ... The spectrophotometer is used to measure colored compounds in the visible region of light (between 350 nm and 800 nm), thus it ... Because a spectrophotometer measures the wavelength of a compound through its color, a dye binding substance can be added so ...
Since the colour of the detection compound is of no consequence, this allows detection in deeply coloured matrices. The 1989 ... as opposed to the more usual chromogenic format, allowing faecal indicator bacteria such as E. coli and E. faecalis to be ... More recently, the chemistry behind enzymatic detection compounds has been updated so that the indicating component is redox ...
... chromogenic compounds MeSH D27.720.233.348 --- fluorescent dyes MeSH D27.720.233.674 --- food coloring agents MeSH D27.720. ... chromogenic compounds MeSH D27.720.470.410.210 --- cross-linking reagents MeSH D27.720.470.410.360 --- intercalating agents ...
This compound and its derivatives have found recent interest as photoconductive materials, chemiluminescence substances, ... chromogenic substrates in analytical redox reactions, dye intermediates, potential antidepressants and tranquilizers, nonlinear ... Julolidine is a heterocyclic aromatic organic compound. It has the formula C12H15N. The first synthesis of julolidine was first ...
Magnetocaloric materials are compounds that undergo a reversible change in temperature upon exposure to a changing magnetic ... Chromogenic systems change colour in response to electrical, optical or thermal changes. These include electrochromic materials ...
... is a chromogenic cephalosporin substrate routinely used to detect the presence of beta-lactamase enzymes produced by ... Once hydrolyzed, the degraded nitrocefin compound rapidly changes color from yellow to red. Although nitrocefin is considered a ... "Novel Method for Detection of B-Lactamases by Using a Chromogenic Cephalosporin Substrate." Antimicrobial Agents and ... "Novel Method for Detection of B-Lactamases by Using a Chromogenic Cephalosporin Substrate." Antimicrobial Agents and ...
Metallic compounds. Exposure to such metallic compounds may be in the form of medication or other environmental exposure. ... Dental plaque: Although usually virtually invisible on the tooth surface, plaque may become stained by chromogenic bacteria ...
Nitro blue tetrazolium is a chemical compound composed of two tetrazole moieties. It is used in immunology for sensitive ... "Fluorescent in situ hybridization employing the conventional NBT/BCIP chromogenic stain". BioTechniques. 42 (6): 756-9. doi: ...
The compound of alkaloids is also used to differentiate the strains. Agrostis canina, Alopecurus myosuroides (G2), Alopecurus ... Sunlight has a chromogenic effect on the mycelium with intense coloration. The disease cycle of the ergot fungus was first ...
HRP catalyzes the conversion of chromogenic substrates (e.g., TMB, DAB, ABTS) into colored products, and produces light when ... This enzyme is suitable for the removal of hydroxylated aromatic compounds (HACs) that are considered to be primary pollutants ... Detection by chemiluminescent substrates has several advantages over chromogenic substrates. The sensitivity is 10- to 100-fold ...
Rudenskaya et al (1998) found that taraxalisin hydrolyzes a chromogenic peptide substrate Glp-Ala-Ala-Leu-pNA optimally at pH ... It contains a wide number of pharmacologically active compounds. Dandelion contains flavonoids including luteolin, apigenin, ... isoquercitrin (a quercetin-like compound), caffeic acid, and chlorogenic acid. Dandelion also contains terpenoids, triterpenes ...
On that evidence, it has been used as a replacement for carcinogenic compounds such as benzidine and o-phenylenediamine. Sigma ... 3,3',5,5'-Tetramethylbenzidine or TMB is a chromogenic substrate used in staining procedures in immunohistochemistry as well as ...
The FDA has approved four variations of the LAL test: gel-clot, turbidimetric, colorimetric, and chromogenic assay. The ... Typical examples of endotoxin binding ligands include histamine, nitrogen-containing heterocyclic compounds, and polymyxin B. ...
NMR data that allowed visualization of intermediates does not support this mechanism or the sulfonamides as the chromogenic ... Schiff reagent with aldehydes is complex with several research groups reporting multiple reaction products with model compounds ...
A very common Ehrlich test is a simple spot test to identify possible psychoactive compounds such as tryptamines (e.g. DMT) and ... Ehmann, A. (1977). "The van URK-Salkowski reagent - a sensitive and specific chromogenic reagent for silica gel thin-layer ... reagent works by binding to the C2 position of two indole moieties to form a resonance stabilised carbenium ion compound. Pill ...
... is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent ... a sensitive and specific chromogenic reagent for silica gel thin-layer chromatographic detection and identification of indole ...
Chromogenic bacteria found in plaque that is left behind due to poor oral hygiene can also cause staining. Other external ... Common practice is to use a prophy cup-a small motorized rubber cup-along with an abrasive polishing compound. There is ...
Ehmann, A. (1977). "The van URK-Salkowski reagent - a sensitive and specific chromogenic reagent for silica gel thin-layer ... It is also particularly useful for localization of proanthocyanidins compounds in plants, resulting in a blue staining. It has ...
Dirigent proteins are members of a class of proteins that dictate the stereochemistry of a compound synthesized by other ... an antibody to one or more proteins of interest that are conjugated to enzymes yielding either luminescent or chromogenic ...
Dirigent proteins are members of a class of proteins that dictate the stereochemistry of a compound synthesized by other ... an antibody to one or more proteins of interest that are conjugated to enzymes yielding either luminescent or chromogenic ... increasing the potential for flatulence and odorous compounds in dogs because when proteins reach the colon in an undigested ...
... chromophoric and chromogenic compositions; and fluorophoric and fluorogenic compounds--all of which are known and described in ... Color-encoding and in-situ interrogation of matrix-coupled chemical compounds. US20020146368 *. Jan 7, 2002. Oct 10, 2002. ... Color-encoding and in-situ interrogation of matrix-coupled chemical compounds. US20060211052 *. May 22, 2006. Sep 21, 2006. ... Screening compound libraries using an optical fiber array device capable of simultaneously performing multiple functional ...
... has role chromogenic compound (CHEBI:75050) keto-phenylpyruvic acid (CHEBI:30851) has ... chromogenic compound Colourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms ... into coloured compounds. They are used in biochemical assays and in diagnosis as indicators, particularly in the form of enzyme ...
Chemicals/CAS: alpha-Macroglobulins; Antifibrinolytic Agents; Caproates; Chromogenic Compounds; Heparin, 9005-49-6; Lysine, 56- ... Chromogenic Compounds · Female · Heparin · Humans · Lysine · Male · Middle Aged · Plasmin · Reagent Kits, Diagnostic · ... Recently, a chromogenic kit for determination of plasmin inhibitor activity, Coamatic® Plasmin Inhibitor, has been developed ...
chromogenic substrate A compound or substance that contains a colour-forming group. ... compound chromosome A chromosome formed by the union of two separate chromosomes, as in attached-X chromosomes or attached-X-Y ... carbohydrate An organic compound based on the general formula Cx (H2O)y, performing many vital roles in living organisms. The ... cryoprotectant Compound preventing cell damage during freezing and thawing processes. Cryoprotectants are agents with high ...
Disclosed herein are a solvent for a chromogenic dye-precursor material for a pressure-sensitive recording paper sheet, ... As the chromogenic dye-precursor material, compounds of triphenylmethanes, diphenylmethanes, xanthenes, thiazines and ... and the solubility of the chromogenic dye-precursor material was examined. As a result, the solubility of the chromogenic dye- ... As the result, the solubility of the chromogenic dye-precursor after 14 days at 20 C. was 8.6 g/100 ml, and the initial colour- ...
Nitrophenol and nitroanilline compounds were used at this time, producing a yellow colouration. The colour of nitrophenol, ... Chromogenic substrates such as ONPG, X-Gal, or X-Glu, together with a specified selectivity of the medium, is the simple ... Chromogenic media offer a range of benefits for the enumeration, detection, and identification of microorganisms The use of ... Overview of Chromogenic Media. By: Jvo Siegrist Product Manager, AnalytiX Issue 3 ...
Chromogenic Compounds (15) • Colorless, endogenous or exogenous pigment precursors that may be transformed by biological ... Cystine Depleting Agents (1) • Compounds and drugs that react with CYSTINE and convert it into a compound that can be more ... Carbonic Anhydrase Inhibitors (12) • A class of compounds that reduces the secretion of H+ ions by the proximal kidney tubule ... Cytochrome P-450 CYP1A2 Inducers (2) • Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP1A2. MeSH ...
... the chromoionophore compounds further comprise a second chromophoric moiety which is insensitive to potassium binding by the ... The invention provides chromoionophore compounds comprising a triazacryptand (TAC) K+ ionophore conjugated to at least a first ... Fluorogenic and chromogenic three-dimensional ionophores as selective reagents for detecting ions in biological fluids. ... These compounds of He et al. are water insoluble, and the conjugated compounds bound to cellulose exhibited relatively low K+- ...
As used herein, the terms "chromogenic compound" and "chromogenic substrate," refer to any compound useful in detection systems ... All of these compounds are commercially available from Sigma.. Of these compounds, pectin was found to be unsuitable when ... Method test media and chromogenic compounds for identifying and differentiating general coliforms and Escherichia coli bacteria ... As used herein, the term "carbon source" is used in reference to any compound which may be utilized as a source of carbon for ...
Tetrazolium Salts: Chromogenic Redox Indicators Tetrazolium salts-especially MTT (M6494, )-are widely used for detecting the ... In peroxisomes, H2O2 is produced by several enzymes that use molecular oxygen to oxidize organic compounds. This H2O2 is then ... This compound emits chemiluminescence upon oxidation in basic aqueous solutions. Emission peaks are at 425 nm (L8455) and 470 ... This compound is susceptible to oxidation, especially in solution. Store solutions under argon or nitrogen. Oxidation may be ...
Furthermore, a silver salt of a compound containing an imino group can be used. Preferred examples of these compounds include a ... Another class of leuco dyes useful in this invention are those derived from so-called "chromogenic dyes". These dyes are ... The leuco dye can be any colorless or slightly colored compound that can be oxidized to a colored form, when heated, preferably ... Other p-phenylenediamines, similar compounds, and their use include those described in Nakamura et al U.S. Pat. No. 5,427,897, ...
Exposure and capsule rupture renders the chromogenic material image-wise accessible to the developer for a patterned image ... An imaging system in which images are formed by image-wise exposing a layer containing a chromogenic material and a ... Specifically, there are triarylmethane compounds, bisphenylmethane compounds, xanthene compounds, thiazine compounds, ... the chromogenic material is an electron donating compound and the developer is an electron accepting compound. Preferably, in ...
Compounds of the general formula ##STR1## wherein R represents an alkyl group of 1 to 3 carbon atoms or the group N(R2)2, in ... Oxidative chromogenic compound or salt thereof and production method thereof, and reagent composition and test instrument using ... Oxidative chromogenic compound or salt thereof and production method thereof, and reagent composition and test instrument using ... In these compounds the substituents R and R1 can assume any position in the phenyl moiety. Compounds in which the moieties R ...
We have developed a chromogenic reagent to screen for nitrilase activity as an alternative to Nesslers reagent. It produces a ... Nitrile compounds are intermediates in the synthesis of pharmaceuticals such as atorvastatin. ... Nitrile compounds are intermediates in the synthesis of pharmaceuticals such as atorvastatin. We have developed a chromogenic ...
The novel photochromic compound of the present invention is a spirooxazine compound having an addition polymerizable organic ... Novel photochromic compound and a polymer comprising the photochromic compound are disclosed. ... Use of oxazine compounds for making chromogenic materials US20090244479A1 (en) * 2008-03-31. 2009-10-01. Diana Zanini. Tinted ... Novel photochromic compound and a polymer comprising the photochromic compound are disclosed. The novel photochromic compound ...
Chromogenic compounds and their use as enzyme substrates US4631119A (en) 1983-11-23. 1986-12-23. W. R. Grace & Co.. Reversible ... Chromogenic compounds and their use as enzyme substrates US4766110A (en) 1981-08-21. 1988-08-23. Ryan James W. Novel complex ... Protective group, compound protected by said group and device for grafting the protective group on the compound to protect it ... Protective group, compound protected by said group and device for grafting the protective group on the compound to protect it ...
A NOVEL CHROMOGENIC COMPOUND OF NORMALLY COLORLESS FORM IS DISCLOSED, HAVING THE STRUCTURAL FORMULA: 7-(O=),5,5-DI(X-)-5,7- ... 1. What chromogenic compound represented by the for- 5 mula: 02H!- X N C E c or [CH8 iHz lHll 2. A chromogenic compound ... providing a chromogenic compound selected from among the above-mentioned compounds and bringing such chromogenic compound into ... Chromogenic compounds US4587343A (en) * 1983-05-09. 1986-05-06. Ciba-Geigy Corporation. Chromogenic 3,3-bisindolyl-4- ...
The nitrite generated is used as a chromogenic agent, obtaining a stable diazo compound at room temperature, which absorbs at ... 2.4 Diazo compound stability The stability of the diazo compound was monitored by spectrophotometrical readings of a solution ... Cooling or coupling stage are unnecessary, due to the stability of the colored diazo compound, which has a maximum absorbance ... Absorption spectra of the diazo compound showed a maximum at 380 nm. Hence absorbance was recorded as function of concentration ...
Nitrocefin-based tests are the preferred method. The reagent is composed of paper disks impregnated with chromogenic ... cephalosporin, which releases a red compound on hydrolysis by a β-lactamase.Performing the test: The disks can be stored in ... 1A positive direct chromogenic β-lactamase test predicts resistance to penicillin, ampicillin, and amoxicillin. ...
Chromogenic Compounds * Lectins * Microscopy, Electron * Nerve Endings / physiology * Nerve Endings / ultrastructure* * ...
... chromogenic reagent, 1,1-Dipheny1-2-picrylhydrazyl, free radical). ... A61K31/33-Heterocyclic compounds * A61K31/335-Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. ... 3)具有双键的有机物为高度不饱和脂肪酸、其盐、或其酯的(1)的组合物。 (3) organic compounds having a double bond is highly unsaturated fatty acid, a salt or ... Composition containing high oxygen stabilized double bonded organic compound CN 200380103936 CN100348184C
Chromium Compounds.. Chromogenic Materials, Electrochromic.. Chromogenic Materials, Photochromic.. Chromogenic Materials, ...
Both natural and artificial compounds have been traditionally Recent Review Articles ... The drawbacks of chromogenic and fluorogenic organic enzymatic substrates are their high cost and low stability, resulting in ... Both natural and artificial compounds have been traditionally used to evaluate enzymatic activities. ...
Chromogenic and fluorogenic tests are described; they are used in conjunction, because of sensitivity effects. The reagents ... IOHSA5; NIOSH-Publication; NIOSH-Contract; Carcinogens; Aromatic-compounds; Pollution; Chemical-reactions; Monitoring; Monitors ... Chromogenic and fluorogenic tests are described; they are used in conjunction, because of sensitivity effects. The reagents ...
Chromium Compounds.. Chromogenic Materials, Electrochromic.. Chromogenic Materials, Photochromic.. Chromogenic Materials, ...
  • Early in her career, her Ph.D. advisor, Allan R. Day, interested her in heterocyclic compounds, and she did early work with aromatic and heterocyclic scaffolds and fluorinated heterocycles. (wikipedia.org)
  • Typical examples of endotoxin binding ligands include histamine, nitrogen-containing heterocyclic compounds, and polymyxin B. However, polymyxin B is known to induce production of interleukin-1, an exogenous pyrogen, and thus must be shown to be absent in the final product if used. (wikipedia.org)
  • 19. The imaging material of claim 5 wherein said electron accepting compound is selected from the group consisting of clay minerals, organic acids, acid polymers, metal salts of aromatic carboxylic acids, oil soluble metal salts of phenol-formaldehyde novalak resins, zinc carbonate and combinations thereof. (google.com)
  • These compounds consist of at least a conjugated chromophore azo (-N=N-) group and two or more aromatic ring groups, which are important classes of organic colorants under different names such as diazotizated calixarene derivatives, "azocalixarenes" [ 10 ]. (hindawi.com)
  • Julolidine is a heterocyclic aromatic organic compound. (wikipedia.org)
  • This enzyme is suitable for the removal of hydroxylated aromatic compounds (HACs) that are considered to be primary pollutants in a wide variety of industrial wastewater. (wikipedia.org)
  • Bisulphite was believed to react with the available aromatic amine functional groups to form N-sulfinic acid groups, Ar-NH-SO2H, followed by reaction with aldehyde to form sulfonamides, Ar-NH-SO2CH(OH)-R. The 1980 NMR data that allowed visualization of intermediates does not support this mechanism or the sulfonamides as the chromogenic product. (wikipedia.org)
  • To identify the bacterial genes involved in formation of the chromogenic compound(s) characteristic of pink disease, we used the virulent strain 1056R and developed an assay that enabled us to reproduce the disease under laboratory conditions ( 7 ). (asm.org)
  • Mexican plum ( Spondias purpurea L.) 'Cuernavaqueña' was harvested at four ripening stages, with the aim of evaluating the concentration of bioactive compounds and antioxidant capacity in the pulp and the epicarp. (scielo.br)
  • Significant correlations (r = 0.60 *** to 0.95 **) between bioactive compounds concentrations and antioxidant activity were obtained. (scielo.br)
  • Horticultural commodities (fruit and vegetables) are the major dietary source of several bioactive compounds of high nutraceutical value for humans, including polyphenols, carotenoids and vitamins. (frontiersin.org)
  • The systematic screening of key bioactive compounds in a wide range of germplasm for the identification of promising genotypes and the restoration of key gene fractions from wild species and landraces may help in reducing the loss of agro-biodiversity, creating a healthier "gene pool" as the basis of future adaptation. (frontiersin.org)
  • All recent studies support that a diet rich in fruit and vegetables is beneficial for human health, suggesting that these key bioactive compounds should be a clear target for enhancement of nutritional value of fresh produce. (frontiersin.org)
  • In related embodiments, the chromoionophore compounds further comprise a second chromophoric moiety which is insensitive to potassium binding by the TAC ionophore, thus providing for dual wavelength detection and absolute determination of K + concentration. (google.com)
  • Sigma offers several chromogenic and chemiluminescent detection reagents for blotting , histology and ELISA applications. (sigmaaldrich.com)
  • Colourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into coloured compounds. (ebi.ac.uk)
  • A pressure-sensitive recording paper sheet comprises a colour-development sheet prepared by coating microcapsules in which a solution of a colourless electron donating chromogenic dye-precursor material having a colouring reactivity has been encapsuled, onto a supporting sheet and a colour-developer sheet prepared by coating a colour-developer which develops a colour on contacting to the chromogenic dye-precursor material onto a supporting sheet. (google.com)
  • The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamat extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). (google.com)
  • 4. The method of claim 3 wherein D is a fluorescent label, a chromogenic label, or an eleotrochemical label. (google.com)
  • 4. The compound of claim 1, wherein said quencher is an acceptor for said fluorescent donor moiety in a FRET pair. (google.es)
  • 6. The compound of claim 4, wherein at least one of said X and Y is an ester derivative of said fluorescent donor or said acceptor. (google.es)
  • 7. The compound of claim 6, wherein said fluorescent donor or acceptor is selected from the group consisting of coumarin dye, acridine dye, rhodamine dye fluorescein dye, eosin dye and rhodol dye. (google.es)
  • Although usually virtually invisible on the tooth surface, plaque may become stained by chromogenic bacteria such as Actinomyces species. (wikipedia.org)
  • One technique for detecting indicator organisms is the use of chromogenic compounds, which are added to conventional or newly devised media used for isolation of the indicator bacteria. (wikipedia.org)
  • Bacteria in marine environments are often under extreme conditions of e.g., pressure, temperature, salinity, and depletion of micronutrients, with survival and proliferation often depending on the ability to produce biologically active compounds. (mdpi.com)
  • The wide array of compounds produced by marine bacteria as an adaptive response to demanding conditions makes them suitable candidates for screening of compounds with commercially interesting biological functions. (mdpi.com)
  • Causes of extrinsic staining include: Dental plaque: although usually virtually invisible on the tooth surface, plaque may become stained by chromogenic bacteria such as Actinomyces species. (wikipedia.org)
  • Chromogenic bacteria found in plaque that is left behind due to poor oral hygiene can also cause staining. (wikipedia.org)
  • This coloration is initiated by the oxidation of glucose to gluconate, which is followed by further oxidation of gluconate to as yet unknown chromogenic compounds. (asm.org)
  • After the chromogenic oxidation reaction catalyzed by HRP, a red water-insoluble precipitate is formed in situ, visualizing the location of the antigen detected by the HRP-conjugated antibody. (wikipedia.org)
  • Calixarenes are ideal frameworks for the development of chromogenic ionophores in the molecular recognition of ionic species of chemical and biological interests since the incorporation of a suitable sensory group into the calixarene results in a tailored chromogenic receptor [ 5 ]. (hindawi.com)
  • Compounds of the general formula ##STR1## wherein R represents an alkyl group of 1 to 3 carbon atoms or the group N(R2)2, in which R2 represents a hydrogen atom, an alkyl group of 1 to 3 carbon atoms, or an acyl group of 1 to 3 carbon atoms, and R1 has the same meaning as R or is a hydrogen atom, are. (google.com)
  • 2. The compound of claim 1, wherein R.sub.1 represents a hydrogen atom. (patentgenius.com)
  • M is a bond or a water soluble organic compound consisting of from 1 to 100 atoms, not including hydrogen, that are selected from the group consisting of carbon, oxygen, nitrogen, phosphorus, boron, and sulfur. (google.com)
  • HRP readily combines with hydrogen peroxide (H 2 O 2 ) and the resultant [HRP-H 2 O 2 ] complex can oxidize a wide variety of chromogenic hydrogen donors. (sigmaaldrich.com)
  • An imaging system in which images are formed by image-wise exposing a layer containing a chromogenic material and a photosensitive composition in which at least the photosensitive composition is encapsulated in a layer of pressure rupturable capsules. (google.com)
  • A color-changing marking composition system, suitable for use in the form of crayons and pencils, comprising a first marking composition comprising wax, a dye, which is other than a Leuco dye and which is capable of changing color upon contact with a color change-inducing compound, and a solvent capable. (google.ca)
  • and a second marking composition comprising wax and a color change-inducing compound, which is capable of inducing a color change in a dye in a marking composition with which it is brought in contact. (google.ca)
  • b) a second marking composition comprising a wax and a color change-inducing compound which when contacted with the dye induces a color change in the dye. (google.ca)
  • 8. The color-changing marking composition system of claim 7, wherein said color change-inducing compound in said marking composition is triethanolamine and oleyl amine combined. (google.ca)
  • However, the disadvantages of these compounds are that they are unstable to alkali and also that they occur only as mixtures ofvarying composition and are thus difficult to meter and standardize exactly. (patentgenius.com)
  • Coloured compounds from these sources are adsorbed into acquired dental pellicle or directly onto the surface of the tooth causing a stain to appear. (wikipedia.org)
  • In this review we will explore how the available biochemical and structural information can be translated into the discovery and development of new compounds that could reverse drug resistance in Gram-negative pathogens. (frontiersin.org)
  • Firstly, toward the eventual enhancement of horticultural crops with bio-functional compounds, the natural genetic variation in antioxidants found in different species and cultivars/genotypes is underlined. (frontiersin.org)
  • Compounds in which the moieties R and R 1 are in the para and/or ortho position are preferred on account of their easier availability. (google.com)
  • In accordance with the invention, binding compounds derivatized with releasable molecular tags specifically bind to selected membrane-associated analytes, after which the molecular tags are released upon activation of cleavage moieties, or sensitizers, anchored in the same membrane as the membrane-associated analytes. (google.com)
  • Disclosed herein are a solvent for a chromogenic dye-precursor material for a pressure-sensitive recording paper sheet, comprising (1) 30 to 80% by weight of p-monoisopropylbiphenyl or a biphenyl mixture of not less than 80% by weight of p-monoisopropylbiphenyl, not more than 20% by weight of m-monoisopropylbiphenyl. (google.com)
  • As the solvent which dissolves the chromogenic dye-precursor material for the pressure-sensitive recording paper sheet, it is demanded that the solvent fulfills the following requirements. (google.com)
  • As the solvent of the chromogenic dye-precursor material for the pressure-sensitive recording paper sheet, which fulfills the above-mentioned requirements, several solvents have been proposed. (google.com)
  • For instance, (1) a mixed solvent comprising more than 30% by weight of isopropylbiphenyl (represented by the formula: ##STR1## less than 55% by weight of polyisopropylbiphenyl and less than 15% by weight of biphenyl, which is used for preparing a solution of the chromogenic dye-precursor material to be contained in the capsules used for coating onto a sheet material for pressure-sensitive recording paper sheets (U.S. Pat. (google.com)