A CHROMATOGRAPHY method using supercritical fluid, usually carbon dioxide under very high pressure (around 73 atmospheres or 1070 psi at room temperature) as the mobile phase. Other solvents are sometimes added as modifiers. This is used both for analytical (SFC) and extraction (SFE) purposes.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
A chromatographic technique that utilizes the ability of biological molecules to bind to certain ligands specifically and reversibly. It is used in protein biochemistry. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Techniques used to separate mixtures of substances based on differences in the relative affinities of the substances for mobile and stationary phases. A mobile phase (fluid or gas) passes through a column containing a stationary phase of porous solid or liquid coated on a solid support. Usage is both analytical for small amounts and preparative for bulk amounts.
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)
Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.
A plant genus of the family LAMIACEAE that is closely related to the European pennyroyal (MENTHA PULEGIUM).
Chromatographic techniques in which the mobile phase is a liquid.
Separation technique in which the stationary phase consists of ion exchange resins. The resins contain loosely held small ions that easily exchange places with other small ions of like charge present in solutions washed over the resins.
A plant genus of the family CLUSIACEAE. Members contain costatolide, calanolides and 4-phenylfuranocoumarins (FUROCOUMARINS).
A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Relating to the size of solids.
Six-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives. Various polyneuropathies are caused by hexane poisoning.
Chromatography on thin layers of adsorbents rather than in columns. The adsorbent can be alumina, silica gel, silicates, charcoals, or cellulose. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A plant genus of the LAMIACEAE family. It is known as a spice and medicinal plant.
Drugs and their metabolites which are found in the edible tissues and milk of animals after their medication with specific drugs. This term can also apply to drugs found in adipose tissue of humans after drug treatment.
Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
Technique whereby the weight of a sample can be followed over a period of time while its temperature is being changed (usually increased at a constant rate).
A benzodiazepine that is used in the treatment of ANXIETY DISORDERS.
Residue generated from combustion of coal or petroleum.
Salts that melt below 100 C. Their low VOLATILIZATION can be an advantage over volatile organic solvents.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
Oils derived from plants or plant products.
A plant genus of the family APIACEAE. The leaves are the source of cilantro and the seeds are the source of coriander, both of which are used in SPICES.
A plant genus of the family LAMIACEAE used to flavor food.
Worthless, damaged, defective, superfluous or effluent material from industrial operations.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
A plant genus of the family APIACEAE used in SPICES.
The 17-alpha isomer of TESTOSTERONE, derived from PREGNENOLONE via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone is used to monitor anabolic drug abuse.
Pesticides or their breakdown products remaining in the environment following their normal use or accidental contamination.
Separation of a mixture in successive stages, each stage removing from the mixture some proportion of one of the substances, for example by differential solubility in water-solvent mixtures. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A non-crystalline form of silicon oxide that has absorptive properties. It is commonly used as a desiccating agent and as a stationary phase for CHROMATOGRAPHY. The fully hydrated form of silica gel has distinct properties and is referred to as SILICIC ACID.
The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
A plant genus of the LAMIACEAE family.
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
A plant genus in the family ROSACEAE and order Rosales. This should not be confused with the genus RHODIOLA which is sometimes called roseroot.
The removal of a soluble component from a liquid mixture by contact with a second liquid, immiscible with the carrier liquid, in which the component is preferentially soluble. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Nanometer-sized, hollow, spherically-shaped objects that can be utilized to encapsulate small amounts of pharmaceuticals, enzymes, or other catalysts (Glossary of Biotechnology and Nanobiotechnology, 4th ed).
A plant genus of the family POLYGALACEAE that contains onjisaponins, xanthones, pyrones, and benzophenones. The name is similar to other snakeroots such as ASARUM; SANICULA; ARISTOLOCHIA; AGERATINA; and others.
Oils which evaporate readily. The volatile oils occur in aromatic plants, to which they give odor and other characteristics. Most volatile oils consist of a mixture of two or more TERPENES or of a mixture of an eleoptene (the more volatile constituent of a volatile oil) with a stearopten (the more solid constituent). The synonym essential oils refers to the essence of a plant, as its perfume or scent, and not to its indispensability.
Methodologies used for the isolation, identification, detection, and quantitation of chemical substances.
An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.
A plant genus of the family LAMIACEAE that contains isoscutellarein-7-O-(allosyl(1-2)glucoside).
The chemical and physical integrity of a pharmaceutical product.
A plant genus of the family ACORACEAE, order Arales, subclass Arecidae most notable for Acorus calamus L. root which contains asarone and has been used in TRADITIONAL MEDICINE.
Inorganic compounds that contain magnesium as an integral part of the molecule.
A plant genus of the family Apocynaceae. It is the source of VINCA ALKALOIDS, used in leukemia chemotherapy.
The destroying of all forms of life, especially microorganisms, by heat, chemical, or other means.
A phase transition from liquid state to gas state, which is affected by Raoult's law. It can be accomplished by fractional distillation.
A plant genus in the LAURACEAE family. Laurus nobilis L. leaves are known for use in SPICES, having a similar flavor as UMBELLULARIA.
A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
A type of ion exchange chromatography using diethylaminoethyl cellulose (DEAE-CELLULOSE) as a positively charged resin. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The sum of the weight of all the atoms in a molecule.
A group of TETRAHYDRONAPHTHALENES containing a keto oxygen.
The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
A chemical process for separating the components of a liquid mixture by boiling and collecting condensed vapors.
Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.
Transparent, tasteless crystals found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite. The compound is insoluble in water or acids except hydrofluoric acid.
Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
The formation of a solid in a solution as a result of a chemical reaction or the aggregation of soluble substances into complexes large enough to fall out of solution.
A method of gel filtration chromatography using agarose, the non-ionic component of agar, for the separation of compounds with molecular weights up to several million.
A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
A group of compounds that are derivatives of octadecanoic acid which is one of the most abundant fatty acids found in animal lipids. (Stedman, 25th ed)
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)
The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.
A biocompatible polymer used as a surgical suture material.
That portion of the electromagnetic spectrum from the UHF (ultrahigh frequency) radio waves and extending into the INFRARED RAYS frequencies.
The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The general name for a group of fat-soluble pigments found in green, yellow, and leafy vegetables, and yellow fruits. They are aliphatic hydrocarbons consisting of a polyisoprene backbone.
A chromatography technique in which the stationary phase is composed of a non-polar substance with a polar mobile phase, in contrast to normal-phase chromatography in which the stationary phase is a polar substance with a non-polar mobile phase.

Field-based supercritical fluid extraction of hydrocarbons at industrially contaminated sites. (1/62)

Examination of organic pollutants in groundwaters should also consider the source of the pollution, which is often a solid matrix such as soil, landfill waste, or sediment. This premise should be viewed alongside the growing trend towards field-based characterisation of contaminated sites for reasons of speed and cost. Field-based methods for the extraction of organic compounds from solid samples are generally cumbersome, time consuming, or inefficient. This paper describes the development of a field-based supercritical fluid extraction (SFE) system for the recovery of organic contaminants (benzene, toluene, ethylbenzene, and xylene and polynuclear aromatic hydrocarbons) from soils. A simple, compact, and robust SFE system has been constructed and was found to offer the same extraction efficiency as a well-established laboratory SFE system. Extraction optimisation was statistically evaluated using a factorial analysis procedure. Under optimised conditions, the device yielded recovery efficiencies of >70% with RSD values of 4% against the standard EPA Soxhlet method, compared with a mean recovery efficiency of 48% for a commercially available field-extraction kit. The device will next be evaluated with real samples prior to field deployment.  (+info)

Simultaneous measurement of fluoroquinolones in eggs by a combination of supercritical fluid extraction and high pressure liquid chromatography. (2/62)

Simultaneous detection of the fluoroquinolone antibiotics ciprofloxacin, enrofloxacin, ofloxacin, and norfloxacin in eggs by a combination of supercritical fluid extraction (SFE) and high pressure liquid chromatography (HPLC) was studied. Lipid matrices that have been considered to result in poor extraction and isolation of fluoroquinolones in eggs were removed first by SFE with supercritical CO(2) alone, and then the fluoroquinolones were extracted by SFE with supercritical CO(2) containing 20% (v/v) methanol for HPLC analysis. A time-course study of the extraction of lipid matrices of eggs suggested that the SFE method successfully removed the matrices within 20 min. When the fluoroquinolones added to control eggs were extracted by SFE, the extraction efficiency was similar to that by the solvent extraction method, giving the recovery percentages from 83 to 96% in a 40 min-extraction time. The fluoroquinolones extracted from eggs by SFE were analyzed simultaneously by HPLC equipped with a fluorescence detector with detection sensitivity at about 10 ppb for the detection limit. The standard calibration profiles of fluoroquinolones showed linear responses to HPLC, showing more than 0.995 for the mean r(2) value. This is the first report of the simultaneous measurement of fluoroquinolones in eggs by a combination of SFE and HPLC. Using the SFE method allowed us to avoid extensive sample preparation such as solvent extraction and chromatographic cleanup that are basically required in extraction of fluoroquinolones.  (+info)

Pesticide residues in canned foods, fruits, and vegetables: the application of Supercritical Fluid Extraction and chromatographic techniques in the analysis. (3/62)

Multiple pesticide residues have been observed in some samples of canned foods, frozen vegetables, and fruit jam, which put the health of the consumers at risk of adverse effects. It is quite apparent that such a state of affairs calls for the need of more accurate, cost-effective, and rapid analytical techniques capable of detecting the minimum concentrations of the multiple pesticide residues. The aims of this paper were first, to determine the effectiveness of the use of Supercritical Fluid Extraction (SFE) and Supercritical Fluid Chromatography (SFC) techniques in the analysis of the levels of pesticide residues in canned foods, vegetables, and fruits; and second, to contribute to the promotion of consumer safety by excluding pesticide residue contamination from markets. Fifteen different types of imported canned and frozen fruits and vegetables samples obtained from the Houston local food markets were investigated. The major types of pesticides tested were pyrethroids, herbicides, fungicides, and carbamates. By using these techniques, the overall data showed 60.82% of the food samples had no detection of any pesticide residues under this investigation. On the other hand, 39.15% different food samples were contaminated by four different pyrethroid residues +/- RSD% ranging from 0.03 +/- 0.005 to 0.05 +/- 0.03 ppm, of which most of the pyrethroid residues were detected in frozen vegetables and strawberry jam. Herbicide residues in test samples ranged from 0.03 +/- 0.005 to 0.8 +/- 0.01 ppm. Five different fungicides, ranging from 0.05 +/- 0.02 to 0.8 +/- 0.1 ppm, were found in five different frozen vegetable samples. Carbamate residues were not detected in 60% of investigated food samples. It was concluded that SFE and SFC techniques were accurate, reliable, less time consuming, and cost effective in the analysis of imported canned foods, fruits, and vegetables and are recommended for the monitoring of pesticide contaminations.  (+info)

Supercritical fluid clean-up of environmental samples for the analysis of polycyclic aromatic hydrocarbons using time-of-flight secondary ion mass spectrometry. (4/62)

A novel sample-pretreatment method for time-of-flight secondary ion mass spectrometry (TOF-SIMS) was developed using supercritical fluid extraction (SFE). In SFE, the extraction efficiency of a certain organic matter is controlled by the pressure and temperature of supercritical CO2. Two-step SFE (1st step at 10 Mpa, 40 degrees C; 2nd step at 30 MPa, 120 degrees C) was applied to diesel exhaust particles containing many kinds of n-alkanes and aromatic species. n-Alkanes and polycyclic aromatic hydrocarbons (PAHs) were extracted in the 1st and 2nd steps, respectively. This selectivity was utilized for the sample preparation of TOF-SIMS analysis. Diesel exhaust particles after the 1st step of extraction were analyzed with TOF-SIMS, aiming at PAHs as analytical targets. The obtained spectrum was simplified, and mass peaks of individual PAHs were easily assigned, because unwanted compounds, like n-alkanes, were selectively removed by SFE. Furthermore, a simple calculation elucidated the outline of the spectrum.  (+info)

Impacts of extraction methods in the rapid determination of atrazine residues in foods using supercritical fluid chromatography and enzyme-linked immunosorbent assay: microwave solvent vs. supercritical fluid extractions. (5/62)

It is an accepted fact that many food products that we eat today have the possibility of being contaminated by various chemicals used from planting to processing. These chemicals have been shown to cause illnesses for which some concerned government agencies have instituted regulatory mechanisms to minimize the risks and the effects on humans. It is for these concerns that reliable and accurate rapid determination techniques are needed to effect proper regulatory standards for the protection of people's nutritional health. This paper, therefore, reports the comparative evaluation of the extraction methods in the determination of atrazine (commonly used in agricultural as a herbicide) residues in foods using supercritical fluid chromatography (SFC) and enzyme-linked immunosorbent assay (ELISA) techniques. Supercritical fluid extraction (SFE) and microwave solvent extraction (MSE) methods were used to test samples of frozen vegetables, fruit juice, and jam from local food markets in Houston. Results showed a high recovery percentage of atrazine residues using supercritical fluid coupled with ELISA and SFC than with MSE. Comparatively, however, atrazine was detected 90.9 and 54.5% using SFC and ELISA techniques, respectively. ELISA technique was, however, less time consuming, lower in cost, and more sensitive with low detection limit of atrazine residues than SFC technique.  (+info)

Stabilized nanoparticles of phytosterol by rapid expansion from supercritical solution into aqueous solution. (6/62)

The basic objective of this work was to form stable suspensions of submicron particles of phytosterol, a water-insoluble drug, by rapid expansion of supercritical solution into aqueous solution (RESSAS). A supercritical phytosterol/CO2 mixture was expanded into an aqueous surfactant solution. In these experiments 4 different surfactants were used to impede growth and agglomeration of the submicron particles resulting from collisions in the free jet. The concentration of the drug in the aqueous surfactant solution was determined by high-performance liquid chromatography, while the size of the stabilized particles was measured by dynamic light scattering. Submicron phytosterol particles (<500 nm) were stabilized and in most cases a bimodal particle size distribution was obtained. Depending on surfactant and concentration of the surfactant solution, suspensions with drug concentrations up to 17 g/dm3 could be achieved, which is 2 orders of magnitude higher than the equilibrium solubility of phytosterol. Long-term stability studies indicate modest particle growth over 12 months. Thus, the results demonstrate that RESSAS can be a promising process for stabilizing submicron particles in aqueous solutions.  (+info)

Isolation of palm tocols using supercritical fluid chromatography. (7/62)

Crude palm oil contains 600 to 1000 ppm of tocols in the form of tocopherols and tocotrienols. These palm tocols have been isolated and analyzed in the past by various chromatographic techniques such as open column chromatography, high-performance liquid chromatography, as well as thin-layer chromatography. Supercritical fluid chromatography (SFC) has emerged as a more advanced chromatographic technique in recent years. The tocols present in palm oil are successfully isolated using SFC. Identification of these tocols is supported by various spectroscopic techniques such as 1H NMR, 13C NMR, and mass spectrometry.  (+info)

Feasibility study of online supercritical fluid extraction-liquid chromatography-UV absorbance-mass spectrometry for the determination of proanthocyanidins in grape seeds. (8/62)

Online coupling of supercritical fluid extraction (SFE) with liquid chromatography (LC)-UV absorbance-electrospray ionization (ESI)-mass spectrometry (MS) is evaluated for the determination of proanthocyanidins in grape seeds. The solid-phase intermediate trap is optimized in order to enhance the collection efficiency for the extracted polar components. Pure supercritical CO2 is used first to remove the oil in the seeds. Then methanol-modified CO2 is used to remove the polar components (e.g., phenolic compounds). Catechin and epicatechin (90%) are extracted out of the de-oiled after 240 min with 40% methanol as a modifier. Both singly-linked (B-type) and doubly-linked (A-type) procyanidins are identified by LC-ESI-MS, as well as their galloylated derivatives. The hyphenated system combines the extraction, separation, and detection in series. The experimental design minimizes the chance of analyte oxidation, degradation, and contamination. The traditional off-line SFE-LC method is also studied for comparison with the online method. Both advantages and disadvantages are observed for the online mode.  (+info)

A column packing material for supercritical fluid chromatography which allows good peak shape to be obtained in the analysis of free fatty acids, etc. and in the analysis of agricultural chemicals, etc., and has excellent durability for repeated analysis. The column packing material for supercritical fluid chromatography includes polymer particles containing cross-linked polymer, the degree of swelling of which after absorbing tetrahydrofuran and the degree of swelling of which after absorbing methanol are both 1.4 or less.
33. A. Rajendran, T. Gilkison, M. Mazzotti. Pressure drop effects in supercritical fluid chromatography, 1st International Conference on Supercritical Fluid Chromatography, Pittsburgh USA, Sept 2007 34. W. Chen, A. Rajendran. Optimization of binary separations in supercritical fluid chromatography, 1st International Conference on Supercritical Fluid Chromatography, Pittsburgh USA, Sept 2007 35. W. Chen, M. Aman Ullah, A. Rajendran. Chiral separation of flurbiprofen by supercritical fluid chro- matography, 1st International Conference on Supercritical Fluid Chromatography, Pittsburgh USA, Sept2007 36. A. Rajendran, S. Farooq, V. Kariwala. Blank correction in dynamic column breakthrough experiments, 9th International Conference on Fundamentals Of Adsorption, Sicily Italy, May 2007 37. A. Rajendran, T. Gilkison, M. Mazzotti. Pressure drop effects in supercritical fluid chromatography, 9th International Conference on Fundamentals Of Adsorption, Sicily Italy, May 2007 38. W. Chen, A. Rajendran. ...
[98 Pages Report] Check for Discount on United States Supercritical Fluid Chromatography (Sfc) Market Report 2017 report by QYResearch Group. In this report, the United States Supercritical Fluid Chromatography (Sfc)...
TY - CHAP. T1 - Polar Lipid Profiling by Supercritical Fluid Chromatography/Mass Spectrometry Method. AU - Yamada, Takayuki. AU - Nagasawa, Yumiko. AU - Taguchi, Kaori. AU - Fukusaki, Eiichiro. AU - Bamba, Takeshi. PY - 2015/4/15. Y1 - 2015/4/15. N2 - Polar lipids, such as phospholipids (PLs) and sphingolipids, are abundant in plant oils and are the major component of biological membranes. These lipids also play important physiological roles in cellular signaling. High-throughput simultaneous analyses for all types of lipids, including polar lipids, are favorable to elucidate the function of individual lipid molecular species or to distinguish among phenotypes. The research field aimed at comprehensive lipid profiling is called lipidomics. Because of the diversity of chemical structures and the wide range of polarities in lipids, a powerful separation technique is required for comprehensive lipid profiling. Supercritical Fluid Chromatography (SFC)/Mass Spectrometry (MS) is the ideal tool for ...
TY - JOUR. T1 - Supercritical fluid chromatography reduction of hydrogen/deuterium back exchange in solution-phase hydrogen/deuterium exchange with mass spectrometric analysis. AU - Emmett, Mark. AU - Kazazic, Sasa. AU - Marshall, Alan G.. AU - Chen, Wei. AU - Shi, Stone D H. AU - Bolaños, Ben. AU - Greig, Michael J.. PY - 2006/10/1. Y1 - 2006/10/1. N2 - The single biggest problem with solution-phase H/D exchange as a mass spectrometric probe of surface exposure in a protein (or protein complex) is back-exchange of H for D after the initial H/D exchange has been quenched. Back-exchange results in loss of pertinent data and also greatly hampers data analysis. Previously, very fast, cold (0-4 °C) HPLC was performed to help reduce back-exchange, but calculated back-exchange still averages ∼30%. In this report, supercritical fluid chromatography replaces HPLC as the desalting/separation technique prior to mass analysis, providing a dramatic reduction in back-exchange compared to the fast, cold ...
Palm oil is known to host a variety of phytonutrients; some having antioxidant property such as the carotenes and vitamin E. These antioxidants are also present in the oil recovered from the palm-pressed fibre. Study was carried out to investigate the presence of coenzyme Q10, yet another non-glyceride compound which possesses antioxidant property in crude palm oil (CPO) and palm fibre oil. Separation of coenzyme Q10 in CPO and palm fibre oil was carried out using supercritical fluid chromatography with ultra violet detection. 1H and 13C NMR were used for its characterisation. Calibration with authentic standard shows that there are 10-80 ppm coenzyme Q10 in CPO while its concentration in palm fibre oil is 1000-1500 ppm.
While supercritical fluid chromatography (SFC) has been available for decades, very few labs have chosen to take advantage of its remarkable chromatographic properties. The separation of isomeric compounds that are usually challenging for high.performance liquid chromatography (HPLC) can be accomplished by SFC. Coupling the exceptional chromatographic properties of SFC with the sensitivity of mass spectrometric detection results in a powerful piece of equipment that very few laboratories have utilized. Glycosphingolipids (GSLs) are characteristic components of eukaryotic cells, found in the carbohydrate-rich cell membrane. They represent hundreds of diverse chemical structures composed of different carbohydrate and ceramide moieties. The simplest hexosylceramides (HexCer), which are neutral GSLs, are represented by glucosylceramide (GluCer) and galactosylceramide (GalCer). GluCer and GalCer undergo their own distinctive metabolic pathways that effect different biological responses. GSL ...
Preparative Supercritical Fluid Chromatography (pSFC). As an environment-friendly approach to purification applications, pSFC is being used routinely for an increasing number of applications.. During the recent years SFC has gained acceptance in drug discovery for high-throughput purification of enantiomers. Hence, pSFC replaces preparative HPLC (pHPLC) as major technology for chiral separations in many pharmaceutical companies. Preparative SFC excels not only at separating and purifying chiral compounds but is also powerful for achiral separations and can be implemented in most steps of drug discovery. It may offer potential advantages over pHPLC for purity upgrading of active pharmaceutical ingredients or drug intermediates, impurity isolation and non-aqueous purification.. The use of pSFC as an alternative option to pHPLC receives also a growing interest for natural products, environmental (pesticides) and petroleum (biofuels) applications. ...
Preparative Supercritical Fluid Chromatography (pSFC). As an environment-friendly approach to purification applications, pSFC is being used routinely for an increasing number of applications.. During the recent years SFC has gained acceptance in drug discovery for high-throughput purification of enantiomers. Hence, pSFC replaces preparative HPLC (pHPLC) as major technology for chiral separations in many pharmaceutical companies. Preparative SFC excels not only at separating and purifying chiral compounds but is also powerful for achiral separations and can be implemented in most steps of drug discovery. It may offer potential advantages over pHPLC for purity upgrading of active pharmaceutical ingredients or drug intermediates, impurity isolation and non-aqueous purification.. The use of pSFC as an alternative option to pHPLC receives also a growing interest for natural products, environmental (pesticides) and petroleum (biofuels) applications. ...
The effect of pressure drop on the performance of supercritical fluid chromatography systems using a modified mobile phase (carbon dioxide + ethanol) was studied. Experiments were performed on a Lichrospher-RP-18 column with phenanthrene as a solute. A wide range of back pressures (130 to 210 bar) and modifier concentrations (2 to 7% w/w) have been explored. Experiments yielding both small and large pressure drops were performed. From these experiments, parameters to describe pressure drop, retention, and column efficiency were extracted, and were used to simulate the dynamics of the chromatographic column. A good match between the experimentally measured and calculated values of pressure drop, retention times, and column efficiency was observed. At low back pressure and modifier composition, significant loss of column efficiency was observed.
François, I., Dos Santos Pereira, A., & Sandra, P. (2009). Comprehensive and off-line supercritical fluid chromatography: reversed phase liquid chromatography for the analysis of complex triglyceride profiles. High Performance Liquid Phase Separations and Related Techniques, 34th International symposium, Abstracts. Presented at the 34th International symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2009 ...
WORCESTER, Mass., July 12, 2013 /PRNewswire/ -- Averica Discovery Announces Winner of First Averica Award for Supercritical Fluid Chromatography (SFC). -...
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RH Alasbahi , The present paper deals with a literature review of the different aspects of supercritical carbon dioxide extraction (SFE). It summarized the general properties of SFE as an advanced and excellent alternative to conventional extractions methods, as well as the advantage and disadvantage of using supercritical CO2 as an environmentally safe and effective solvent. The study also covered the different applications of SFE in food and pharmaceutical processing, and to extract valuable compounds with bioactivities such as antioxidant, antitumor and antibacterial from plant species as well as to produce valuable compounds form industry by-products and new functional ingredients that can be used by the food industry. The study also highlighted the use of SFE in food safety and environmental protection such as the detection/quantification as well as the removal of food and environmental pollutants.. ...
A one step supercritical fluid chromatography process has been developed using a semi-preparative supercritical fluid chromatography scale plant designed and built in-house, for isolation and purification of polyunsaturated fatty acid ethyl esters from different origins (fish and algae). A wide range of experimental conditions (pressure, temperature, sample load, co-solvent rate and CO2 flow rate); columns (stationary phase and particle size); and UV/vis detectors have been investigated to optimise the isolation and purification of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from an algae oil rich in EPA, and a fish oil rich in EPA and DHA. The particle size, followed by the stationary phase, sample loading, temperature/pressure and feed oil composition, were found to be the most important parameters for achieving separation. Under optimised conditions, EPA at greater than 95% purity from both oils and DHA at greater than 80% purity from fish oil was obtained in a single pass and ...
(PRWEB) September 10, 2014 -- The European Supercritical fluid chromatography reagents report defines and segments the concerned market in Europe with analysis
Mass spectrometry (MS) is a technique widely implemented for the measurement of environmental pollutants. A critical tool for the analysis of persistent organic pollutants (POPs) over several decades, MS as coupled with liquid and gas chromatography (LC and GC) techniques enables the analysis of emerging POPs. The aim of this thesis was to investigate the use of alternative MS-based techniques to assist specific analytical challenges including separation of stereoisomers using supercritical fluid chromatography (SFC), reduced ionization competition with appropriate mobile phase additives, and applied rotationally averaged collision-cross section (CCS) of ions via ion mobility measurements of emerging POPs.. Chromatographic efficiency improvements for the brominated flame retardant, hexabromocyclododecane (HBCDD), were implemented through the development of two supercritical fluid chromatography (SFC) methods. Based on the inherent qualities of supercritical fluids, separation of both predominant ...
Mass spectrometry (MS) is a technique widely implemented for the measurement of environmental pollutants. A critical tool for the analysis of persistent organic pollutants (POPs) over several decades, MS as coupled with liquid and gas chromatography (LC and GC) techniques enables the analysis of emerging POPs. The aim of this thesis was to investigate the use of alternative MS-based techniques to assist specific analytical challenges including separation of stereoisomers using supercritical fluid chromatography (SFC), reduced ionization competition with appropriate mobile phase additives, and applied rotationally averaged collision-cross section (CCS) of ions via ion mobility measurements of emerging POPs.. Chromatographic efficiency improvements for the brominated flame retardant, hexabromocyclododecane (HBCDD), were implemented through the development of two supercritical fluid chromatography (SFC) methods. Based on the inherent qualities of supercritical fluids, separation of both predominant ...
TY - JOUR. T1 - Highly porous organic nanoparticles formed from supercritical carbon dioxide mediated sol-emulsion-gel method. AU - Lee, Jun Young. AU - Kim, Jung Hyun. PY - 2004/5/5. Y1 - 2004/5/5. N2 - Highly porous organic nanoparticles have been prepared by adapting a novel method, sol-emulsion-gel process, through stable dispersion of nanometer-scaled emulsion droplets into continuous phase of supercritical carbon dioxide (ScCO2), sol-gel chemistry in emulsion droplets, and then supercritical drying. This principle offers faithful preparation of nanoparticles (35-90 nm in diameter) having pores of 1-3 nm in radius and high specific surface area (over 2000 m2/g).. AB - Highly porous organic nanoparticles have been prepared by adapting a novel method, sol-emulsion-gel process, through stable dispersion of nanometer-scaled emulsion droplets into continuous phase of supercritical carbon dioxide (ScCO2), sol-gel chemistry in emulsion droplets, and then supercritical drying. This principle offers ...
A specialty phase designed for SFC with a high density Diol surface coverage which ensures separations better and more reproducible than conventional unbonded silica. GreenSep Diol is particularly suitable for acidic and basic analytes.
Chiral analysis has become increasingly important in todays laboratories. There are several advantages when using SFC to screen and purify these compounds compared to HPLC. In this episode we will talk about the workflow of chiral analysis, applications areas within the pharmaceutical industry, and advantages of using SFC as it relates to analytical and preparative chromatography. ...
The Laboratory for the Analysis of Medicines (LAM) has developed a solid expertise in drug analysis and bioanalysis. Its scope of interest has been extended to diagnostic biomarkers and biopharmaceuticals. Research and routine activities take place in a quality environment.
TY - JOUR AU - Žižović, Irena AU - Stamenić, Marko AU - Orlović, Aleksandar AU - Skala, Dejan PY - 2005 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/843 AB - In this paper the essential oil supercritical carbon dioxide extraction from leaves of Lamiaceae family species was studied. Recent investigations of Lamiaceae family essential oil storage have shown that most of the oil is found in peltate glandular trichomes on the leaf surface. The effect of supercritical CO2 on the peltate glands was investigated by Scanning Electron Microscopy. It was observed that exposure to supercritical CO2 led to disruption of the peltate glands and essential oil release. This phenomenon was used as a basic hypothesis of the mathematical model of the supercritical fluid extraction with CO2. The model was applied to simulate basil, rosemary, marjoram and pennyroyal supercritical CO2 extraction on the existing experimental data. An average deviation from the experimental data was less than 0.83%. The ...
The piquant and peppery flavor of American Blue and Roquefort cheese is largely due to the short and medium chain fatty acids, methyl ketones and secondary alcohols. The free fatty acids contribute flavor themselves and are also precursors of methyl ketones. Lipase action during the cheese ripening leads to formation of free fatty acids (FFA). The short chain FFA (C6 to C10) are more peppery in flavor than long chain FFA. Conventional methods of FFA analysis suffer from limitations such as loss of volatile fatty acids during derivatization of samples and difficulties in extraction and separation of short, medium and long chain fatty acids in a single analysis. Enhanced FFA recoveries from spiked matrix samples were obtained at 680 atm by SFE/SFC procedure with a 5% methanol modifier containing 1% acetic acid. A procedure was developed utilizing supercritical fluid extraction to isolate the FFA and subsequently separate and quantitate the FFA with supercritical fluid chromatography. The ...
Kenaf (|i|Hibiscus cannabinus|/i|) from the family Malvaceae, is a valuable fiber plant native to India and Africa and is currently planted as the fourth commercial crop in Malaysia. Kenaf seed oil contains alpha-linolenic acid, phytosterol such as |i|β|/i|-sitosterol, vitamin E, and other antioxidants with chemopreventive properties. Kenaf seeds oil (KSO) was from supercritical carbon dioxide extraction fluid (SFE) at 9 different permutations of parameters based on range of pressures from 200 to 600 bars and temperature from 40 to 80°C. They were 200/40, 200/60, 200/80, 400/40, 400/60, 400/80, 600/40, 600/60, and 600/80. Extraction from 9 parameters of KSO-SFE was screened for cytotoxicity towards human colorectal cancer cell lines (HT29) and mouse embryonic fibroblast (NIH/3T3) cell lines using MTS assay. KSO-SFE at 600/40 showed the strongest cytotoxicity towards HT29 with IC|sub|50|/sub| of 200 µg/mL. The IC|sub|50|/sub| for NIH/3T3 was not detected even at highest
The solubility of heptanoic acid and octanoic acid in supercritical carbon dioxide has been determined at temperatures of (313.15, 323.15, and 333.15) K over a pressure range of (8.5 to 30.0) MPa, depending upon the solute. The solubility of heptanoic acid ranged from a solute concentration of (0.08 ± 0.03) kg • m -3 (T = 323.15 K, p = 8.5 MPa) to (147 ± 0.2) kg • m -3 (T = 323.15 K, p = 20.0 MPa). The lowest octanoic acid solubility obtained was a solute concentration of (0.40 ± 0.1) kg • m -3 (T = 333.15 K, p = 10.0 MPa), while the highest solute concentration was (151 ± 2) kg • m -3 (T = 333.15 K, p = 26.7 MPa). In addition, solubility experiments were performed for nonanoic acid in supercritical carbon dioxide at 323.15 K and pressures of (10.0 to 30.0) MPa to add to the solubility data previously published by the authors. In general, carboxylic acid solubility increased with increasing solvent density. The results also showed that the solubility of the solutes decreased with ...
TY - JOUR. T1 - Highly Fluorous Complexes of Ruthenium and Osmium and Their Solubility in Supercritical Carbon Dioxide. AU - Berven, Bradley. AU - Koutsantonis, George. AU - Skelton, Brian. AU - Trengove, R.D.. AU - White, Allan. PY - 2009. Y1 - 2009. N2 - A series of ruthenium and osmium complexes containing highly fluorous diphosphine ligands FPPF = (F13C6C6H4-p)2P(CH2)2P(p-C6H4C6F13)2 (dfppe) and (F13C6C6H4-p)2P(CH2)3P(p-C6H4C6F13)2 (dfppp) has been prepared. The fluorous diphosphine ligands incorporate four C6F13 fluoro-ponytails, and these have been effective in solubilizing the complexes in supercritical carbon dioxide (scCO2). Precise solubility measurements in scCO2 were performed for some of the complexes. The new complexes [MX2(FPPF)2] and [MX(FPPF)(η-C5H5)], M = Ru, Os, X = Cl, Br, have been characterized by a number of spectroscopic techniques and their electrochemical properties measured, three of the ruthenium complexes also being characterized by single-crystal X-ray studies. ...
This study discusses utilization of supercritical carbon dioxide for impregnation of cellulose acetate films with thymol in order to produce material with anti-biofilm activity against Pseudomonas aeruginosa and Staphylococcus aureus. Analysis of anti-biofilm activity of cellulose acetate beads impregnated with thymol suggested that optimal thymol loading was in the range from 26% to 30% for efficient reduction of biofilm formation and eradication of pre-formed biofilms. Polymer films were fabricated by the solvent casting method from polymer solutions of different contents, and loaded with thymol using supercritical carbon dioxide at 15.5 MPa and 35 degrees C. The film containing 30% of thymol (F1 30%) exhibited substantial anti-adhesion properties inhibiting biofilm formation on its surface and considerably reduced formation of biofilms on the surrounding surfaces (up to 80%) by all tested strains including antibiotic resistant P. aeruginosa DM50 and methicillin-resistant S. aureus ...
The effects of microwave irradiation (2.45 GHz, 200 W) on glycosylation promoted by a solid super acid in supercritical carbon dioxide was investigated with particular attention paid to the structure of the acceptor substrate. Because of the symmetrical structure and high diffusive property of supercritical carbon dioxide, microwave irradiation did not alter the temperature of the reaction solution, but enhanced reaction yield when aliphatic acceptors are employed. Interestingly, the use of a phenolic acceptor under the same reaction conditions did not show these promoting effects due to microwave irradiation. In the case of aliphatic diol acceptors, the yield seemed to be dependent on the symmetrical properties of the acceptors. The results suggest that microwave irradiation do not affect the reactivity of the donor nor promoter independently. We conclude that the effect of acceptor structure on glycosylation yield is due to electric delocalization of hydroxyl group and dielectrically symmetric
Effect of supercritical carbon dioxide on micro-mechanical properties of electrodesposited goldEffect of supercritical carbon dioxide on micro-mechanical properties of electrodesposited gold ...
In 1822, almost 200 years ago, Baron Charles Cagniard de Latour (1777-1859) discovered the critical phenomena or critical state [1] [2]. At that time, it was described as a curiosity. However, it is now used as an advanced extraction and analytical technology in industry and research. Extraction with supercritical fluids (SFs) was welcome from the very beginning. In the present paper, the application to chromatography of the critical phenomena of compressed gases or overheated liquids as supercritical fluids will be discussed. Supercritical Fluid Chromatography (SFC) received an uneasy welcome, mainly because of the lack of commercially available analytical instruments. Even today, only a small number of industrial companies are manufacturing SFC instrumentation. A very small spectrum of columns is manufactured specially for SFC. SFC is not accepted by Pharmacopeia committees for the analysis of drugs and medical forms to the same extent as Gas Chromatography, High-Performance Liquid Chromatography or
TY - JOUR. T1 - Modeling of diffusivities in supercritical carbon dioxide using a linear solvation energy relationship. AU - Wang, Tao. AU - Wang, Xiuyun. AU - Smith, Richard L.. PY - 2005/8/1. Y1 - 2005/8/1. N2 - A linear solvation energy relationship (LSER) method was used to develop a predictive model for the diffusivities of organic solutes in supercritical CO2 at infinite dilution. The LSER model was based on the diffusivities of 18 solutes and 104 data points for sc-CO2 in the range of 32-60°C and 8-100 MPa. The independent variables in the model were empirically determined descriptors of the solute molecules and the dipolarity/polarizability of CO2 at a given density. The model was tested for prediction accuracy by using the diffusivities of 10 solutes not included in the database. The model provided relative deviations less than 10% in the correlation and prediction of the diffusivities in supercritical CO 2 of the organic solutes considered. The accuracy of the proposed LSER model is ...
Alibaba.com offers 198 supercritical co2 fluid extraction device products. About 56% of these are other pharmaceutical machinery, 1% are oil pressers, and 1% are laser beauty equipment. A wide variety of supercritical co2 fluid extraction device options are available to you,
The presence of carbon dioxide in natural gas, synthetic gas and liquid streams has prompted the industrial community to examine the properties of carbon dioxide mixtures with the intent of finding novel methods for removing this acidic impurity. Carbon dioxide is also of interest to researchers because it possesses a readily accessible critical point. This has stimulated studies of the phase behaviour and thermodynamic properties of supercritical fluid mixtures, particularly in systems used in supercritical fluid chromatography (SFC) and supercritical fluid extraction (SFE). For both of these applications, it is important to obtain information pertaining to the vapour-liquid phase boundaries for the carbon dioxide mixtures and their thermodynamic properties over a wide range of pressure and temperature. The (CO: + MeOH) system is of interest to applied research on fluid properties because the pure liquids have widely differing critical points. -- There are many experimental issues associated ...
TY - JOUR. T1 - Selective extraction of phospholipids from whey protein phospholipid concentrate using supercritical carbon dioxide and ethanol as a co-solvent. AU - Sprick, B.. AU - Linghu, Z.. AU - Amamcharla, J. K.. AU - Metzger, L. E.. AU - Smith, J. S.. N1 - Funding Information: We thank Midwest Dairy Foods Research Center (St. Paul, MN) for their financial support. This project is Kansas State Research and Extension contribution number 18-150-J. This work was partially supported by the USDA National Institute of Food and Agriculture, Hatch project 1014344. PY - 2019/12. Y1 - 2019/12. N2 - In recent years, using dairy phospholipids (PL) as functional ingredients has increased because PL have nutritional benefits and functional properties. In this study, a novel 2-step supercritical fluid extraction (SFE) process was used to extract whey protein phospholipid concentrate (WPPC), a dairy co-product obtained during the manufacture of whey protein isolate, for PL enrichment. In the first step, ...
The aim of this work was to evaluate the potential of supercritical carbon dioxide (CO2) to extract Fatty Acid Methyl Esters (FAME) from the microalgae Nannochloropsis oculata (N. oculata) at low temperatures (37 and 55 oC) and pressures (5.9 and 7.6 megapascals (MPa)). A qualitative gas chromatography (GC) analysis showed that the individual FAMEs extracted varied depending on the co-solvent (methanol or hexane) used with supercritical CO2. Using hexane, FAME compounds produced were similar to those extracted with soxhlet extraction alone while longer chain FAME were produced when methanol was the co-solvent. The effects of pressure and temperature variations were shown to be of statistical significance. The chromatograms produced in this work demonstrate that altering one of these parameters (co-solvent, temperature, pressure) can produce different compounds owing to the tunability of the technique.
TY - JOUR. T1 - Effects of hydrostatic pressure and supercritical carbon dioxide on the viability of Botryococcus braunii algae cells. AU - Yildiz-Ozturk, Ece. AU - Ilhan-Ayisigi, Esra. AU - Togtema, Arnoud. AU - Gouveia, Joao. AU - Yesil-Celiktas, Ozlem. PY - 2018/5/1. Y1 - 2018/5/1. N2 - In bio-based industries, Botryococcus braunii is identified as a potential resource for production of hydrocarbons having a wide range of applications in chemical and biopolymer industries. For a sustainable production platform, the algae cultivation should be integrated with downstream processes. Ideally the algae are not harvested, but the product is isolated while cultivation and growth is continued especially if the doubling time is slow. Consequently, hydrocarbons can be extracted while keeping the algae viable. In this study, the effects of pressure on the viability of B. braunii cells were tested hydrostatically and under supercritical CO2 conditions. Viability was determined by light microscopy, ...
The effects of organic modifier and temperature on the enantioseparation of 10 triazoles and eight imidazoles, using supercritical fluid chromatography with the Chiralpak AD column, have been investigated in this work. For this purpose four different organic modifiers (methanol, ethanol, 2-propanol and acetonitrile) were evaluated. Only in the case of two compounds could the enantiomeric separation not be achieved with any of the modifiers tested; the rest of compounds were baseline or partially resolved with at least one of the modifiers. The alcohol-type modifiers provided the best results in terms of retention time and resolution. In general, retention increased in the order methanol | ethanol | 2-propanol; moreover it was possible to establish a relationship between the retention and the number of aromatic rings and dioxolane groups in the molecule, that is, the higher the number is, the higher the retention time. From the study of the temperature effect, the enthalpy-entropy compensation was
The first three chapters of the book discuss the various chromatographic and mass spectroscopic techniques now available. Chapters 3-8 cover the complementary methods, based on the combination of mass spectroscopy with various chromatographic techniques such as high-performance liquid chromatography, gas chromatography and supercritical fluid chromatography.
The first three chapters of the book discuss the various chromatographic and mass spectroscopic techniques now available. Chapters 3-8 cover the complementary methods, based on the combination of mass spectroscopy with various chromatographic techniques such as high-performance liquid chromatography, gas chromatography and supercritical fluid chromatography.
Combining state-of-the-art media manufacturing with the industry leading column technology, Viridis Supercritical Fluid Chromatography (SFC) columns bring a new level of reproducibility to the world of laboratory scale purification. Viridis SFC columns are available for analytical and preparative chromatography as Viridis SFC 2-Ethylpyridine columns and Viridis SFC Silica columns. Larger preparative column formats are manufactured using Waters patented Optimum Bed Density (OBD) Technology. 2-Ethylpyridine chemistry is successfully used for a wide range of achiral SFC applications due to its retention, peak shape and selectivity properties. Viridis SFC 2-ethylpyridine columns also provide high reliability and reproducibility and can be used for analytical and preparative applications. Based on Waters long history of chromatographic silica production, the Viridis SFC Silica columns are designed to be highly reproducible and predictable based on tight product specifications and very low metal content.
The supercritical carbon dioxide extraction (SC-CO2) of fish oil was studied using the viscera and skin of African catfish as a raw material and the CO2 as supercritical fluid solvent. A central composite design of response surface methodology (RSM) was employed to optimize the SC-CO2 extraction variables. The response variable (Y) oil yield was executed against the four independent variables namely pressure, temperature, flow rate and the soaking time. The statistical analysis showed, pressure was the most significant linear factor on oil yield. Furthermore, the oil yield was varied with the interaction effects of pressure, temperature and flow rate. Optimum points were obtained within the studied variables range at 65°C temperature, 35 MPa pressure, 2.6 mL/min flow rate and 3.6 h soaking time with maximum oil yield 66.96 and 40.6% from viscera and skin, respectively. The principal fatty acids in terms of concentration were oleic and docosahexaenoic acids respectively. The main objective of ...
The high viscosity of ionic liquids is an impediment to their use in solvent-based processes. This property is even higher when ionic liquids are combined with solid solute. When SC-CO 2 (supercritical carbon dioxide) is dissolved in an ionic liquid, the mixture viscosity can be considerably reduced: at 25 MPa the mole fraction of CO 2 in [BMIm + ][PF 6-] reaches 80% and the viscosity is reduced by 90%. Ionic liquids are so numerous and expensive as well as high-pressure processes. Although both have great potential to make processes safer, cleaner and more efficient. That is why to develop an ionic liquid solvent-based processes using micro-device. The main objective of using this apparatus in this study is to allow ionic liquid screening. An additional advantage of the small length scale is the potential for high-pressure applications due to lower mechanical stress in the micro-device material. Furthermore, the micro-device developed [1,2] is transparent, uses micro-capillaries technology and resist
Colloidal carbon spheres were synthesized by the carbonization of squalane, a nonvolatile hydrocarbon solvent, in supercritical carbon dioxide. Precise pressure modulation of the fluid medium led to size controlled growth of carbon spheres ranging from 300-1500 nm in diameter. This unique synthetic approach of carbonizing a hydrocarbon suspension in supercritical fluid is found to suppress any particle aggregation, resulting in excellent sphere monodispersity. Core-shell hybrid structures of C-Ge were subsequently formed by inducing the growth of 10-40 nm sized germanium nanocrystals from the spheres in a hierarchical bottom-up approach. Extensive characterization of the spheres and nanocrystals was conducted using transmission and scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, Raman and thermogravametric analysis. Assemblies of nanocrystal modified carbon colloids impart outstanding superhydrophobic properties due to the combined nano- and micro-structuring ...
Bilberry seed oils extracted with supercritical carbon dioxide (SC-CO2) for 80 min at 20, 35, and 50 MPa and at 40°, 50° and 60 °C were evaluated to compare the yield, composition, and antioxidant recovery. Analyses of fatty acids, free radical scavenging activity (DPPH), vitamin E and peroxide contents revealed that yield, vitamin E, efficient concentration (EC50), and Peroxide value (PV) varied significantly among the obtained bilberry seed oils, whereas the fatty acid compositions were similar. The oil extracted at 20 MPa and 60 °C had the best recovery of vitamin E and the lowest EC50 and PV. The high levels of vitamin E and polyunsaturated fatty acids, as well as the low ω6/ω3 ratios (|1) and the low PVs in all the extracts suggest bilberry seed oil is a valuable source of bioactive compounds and high potential for use of bilberry by-product extracts in added value foods and nutraceutical products.
TY - JOUR. T1 - Application of supercritical fluid extraction to components of crude drugs and plants. III. Extraction of pigments from lithospermum root and licorice root. AU - Manabe, A.. AU - Tokumori, T.. AU - Sumida, Y.. AU - Yoshida, T.. AU - Hatano, T.. AU - Yazaki, K.. AU - Okuda, T.. PY - 1987/1/1. Y1 - 1987/1/1. UR - http://www.scopus.com/inward/record.url?scp=0023179119&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0023179119&partnerID=8YFLogxK. U2 - 10.1248/yakushi1947.107.7_506. DO - 10.1248/yakushi1947.107.7_506. M3 - Article. C2 - 3694459. AN - SCOPUS:0023179119. VL - 107. SP - 506. EP - 510. JO - Yakugaku Zasshi. JF - Yakugaku Zasshi. SN - 0031-6903. IS - 7. ER - ...
The improved one-pot synthesis of dimethyl carbonate and propylene glycol from propylene oxide, supercritical carbon dioxide, and methanol with potassium bicarbonate as the catalyst has been reported in this paper. As far as we know, it is the first time to use potassium bicarbonate only as the catalyst in the production process which is simple and cheap. Satisfactory conversion rate of propylene oxide and yield of the products could be achieved at the optimized conditions with quite a small amount of by-products. Our new method offers an attractive choice for the production of dimethyl carbonate in large-scale industry efficiently and environmental friendly ...
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This publication offers an outline of simple rules of SFE in addition to in-depth studies of either on- and off-line SFE equipment. The online coupling of SFE with either chromatographic and spectroscopics suggestions has been the topic of loads of examine attempt and is handled intimately. more moderen advancements, corresponding to off-line SFE of sturdy and liquid matrices, are commencing to allure loads of curiosity, and the insurance of those components will turn out of specific price to the analytical chemist. The overseas crew of authors has illustrated those issues with many `state-of-the-art purposes, and every bankruptcy presents a accomplished record of references. For the comfort of the reader, an appendix which includes strain conversion scales and supercritical fluid carbon dioxide density tables looks on the finish of the e-book ...
Abstract The vector analysis indicates that the heat recuperation depends not only on the values of heat transfer coefficient and temperature difference, but also on their coordination for the supercritical fluids. The splitting flow improves the coordination degree between temperature difference and heat transfer coefficient in low temperature recuperator, and increases the inlet temperature of heater and reduces the heat exhaust in the precooler, which leads ...
The market report Essential Oils Market by Types (Citronella Oil, Clove Leaf Oil, Cornmint Oil, Eucalyptus Oil, Geranium Oil, Jasmine Oil, Lavender Oil, Lemon Oil, Lime Oil, Orange Oil, Peppermint Oil, Rosemary Oil, Spearmint Oil, Tea Tree Oil, and Other Oil Types), Method of Extractions (Distillation, Carbon Dioxide Extraction, Cold Press Extraction, Solvent Extraction, and Other Extraction Methods), Applications (Food & Beverages, Spa & Relaxation, Medical, Cleaning & Home, and Other Applications), Distribution Channels (Direct Distribution, Multi-Level Marketing (MLM) Distribution, and Retail Distribution) and Region - Forecast to 2028. The essential oils market is growing at a CAGR of 11.2% by 2028, owing to the growing prevalence of cardiovascular diseases.. Browse the complete report with 564 data tables and 94+ figures here: https://www.strategymrc.com/report/essential-oils-market/toc We offer a 15% customization to be added within the report at no extra cost.. To know more post your ...
Aromatherapy is the therapeutic use of pure essential oils through topical application or inhalation. Essential Oils are volatile aromatic substances. The oils are extracted mostly through steam distillation from herbs, flowers, seeds, barks or woody portions of plants, although there are other methods of extraction, including cold pressing (citrus oils), solvent extractions (absolutes) and carbon dioxide extraction.
Background The amount of extracorporeal carbon dioxide removal may influence respiratory drive in acute respiratory distress syndrome (ARDS) patients undergoing extracorporeal membrane oxygenation (ECMO). The authors evaluated the effects of different levels of extracorporeal carbon dioxide removal in patients recovering from severe ARDS undergoing pressure support ventilation (PSV) and neurally adjusted ventilatory assist (NAVA). Methods The authors conducted a prospective, randomized, crossover study on eight spontaneously breathing ARDS patients undergoing venovenous ECMO since 28 ± 20 days. To modulate carbon dioxide extraction, ECMO gas flow (GF) was decreased from baseline resting protective conditions ( i.e. , GF100%, set to obtain pressure generated in the first 100 ms of inspiration against an occluded airway less than 2 cm H 2 O, respiratory rate less than or equal to 25 bpm, tidal volume less than 6 ml/kg, and peak airway pressure less than 25 cm H 2 O) to GF50%-GF25%-GF0% during ...
The procedures for the extraction and separation of lipids and nutraceutics from microalgae using classic solvents have been frequently used over the years. However, these production methods usually require expensive and toxic solvents. Based on our studies involving the use of eco-sustainable methodologies and alternative solvents, we selected ethanol (EtOH) and cyclopentyl methyl ether (CPME) for extracting bio-oil and lipids from algae. Different percentages of EtOH in CPME favor the production of an oil rich in saturated fatty acids (SFA), useful to biofuel production or rich in bioactive compounds. The proposed method for obtaining an extract rich in saturated or unsaturated fatty acids from dry algal biomass is disclosed as eco-friendly and allows a good extraction yield. The method is compared both in extracted oil percentage yield and in extracted fatty acids selectivity to extraction by supercritical carbon dioxide (SC-CO2).
Copper(ii) can be extracted in supercritical CO2 from a room temperature ionic liquid using CO2-philic fluorinated β-diketonate ligands; thanks to the 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (BMIMTf2N) ionic liquid properties, there is no need to add modifiers to the neat supercritical
Analytical Chemistry, Environmental Analysis, Carbon Dioxide Emulsions, Artificial Photosynthesis, Humic Materials, Fluorescence Spectroscopy, Metal Speciation, Vitamin E Oxidation Reduction, Enhanced Oil Recovery. Fluorescence quenching and enhancement phenomena are being utilized to assess binding reactions of metal ions and organic compounds including fulvic and humic acids, Alpha-tocopherol (vitamin E) is being studied to elucidate oxidation and reduction reactions, Liquid and supercritical carbon dioxide droplets are stabilized by particles creating emulsions that have several advantages for carbon dioxide sequestration in geologic formations or the deep oceans and can also be employed for enhanced oil recovery and other valuable applications, Artificial photosynthesis research is being conducted to convert carbon dioxide and water into hydrocarbon fuels. ...
Alternatively, but not commercially significant, is the so-called Henkel process or Raecke process, named after the company and patent holder, respectively. This process involves the rearrangement of phthalic acid to terephthalic acid via the corresponding potassium salts.[7][8] Terephthalic acid can be prepared in the laboratory by oxidizing various para-disubstituted derivatives of benzene, including caraway oil or a mixture of cymene and cuminol with chromic acid.. The use of carbon dioxide overcomes many of the problems with the original industrial process. Because CO2 is a better flame inhibitor than N2, a CO2 environment allows for the use of pure oxygen directly, instead of air, with reduced flammability hazards. The solubility of molecular oxygen in solution is also enhanced in the CO2 environment. Because more oxygen is available to the system, supercritical carbon dioxide (Tc = 31 °C) has more complete oxidation with fewer byproducts, lower carbon monoxide production, less ...
The presence of Alicyclobacillus acidoterrestris, a thermoacidophilic and spore-forming bacterium, in pasteurized acidic juices poses a serious problem for the processing industry. Therefore, the use of other more effective techniques, such as high hydrostatic pressure (HHP) and supercritical carbon dioxide (SCCD), is considered for preserving juices in order to inactivate these bacteria, while reducing the loss of nutrients and sensory quality of juices. On the other hand, HHP and SCCD when combined with a moderately elevated temperature can induce germination of bacterial spores, making them more vulnerable to inactivation. The spore germination can be also induced by nutrients, such as L-alanine or a mixture of asparagine, glucose, fructose and potassium ions (AGFK). The aim of this work was to determine whether applying activating agents: HHP, SCCD and nutrient germinants (L-alanine and the AGFK mixture), could influence the number of spores which start to germinate and how this affects the ...
Michael T. Combs, graduate student in chemistry, recently received the Student Research Award in Supercritical Fluids for an outstanding publication describing research in the use of supercritical fluids in analytical chemistry. The award was presented by the Tri-State and Mid-west Supercritical Fluid Discussion Groups at the Atlanta-Pittsburgh Conference on Analytical Chemistry. The award of $250 plus plaque is presented to an undergraduate or graduate student who served as the primary author of a paper published or accepted for publication during the 1996 calendar year. Judging was based on the technical content, research approach and originality, and writing style. The title of his paper was Comparison of Supercritical Fluoroform and Carbon Dioxide for Extraction of Sulfonamides from Various Food Matrices. Combss thesis research was done under the supervision of L.T. Taylor in the chemistry department ...
Carbon dioxide is a renewable resource of carbon when we consider the reuse of existing CO2 as a carbon source for producing chemicals. The development of new applications is of major interest from the point of view of carbon dioxide sequestration and within the scope of green chemistry. For example, using CO2 instead of CO or COCl2 for chemical synthesis constitutes an attractive alternative avoiding hazardous and toxic reactants. However, it has the lowest chemical reactivity, which is a serious drawback for its transformation. Supercritical CO2 as a reaction medium offers the opportunity to replace conventional organic solvents. Its benign nature, easy handling and availability, non volatile emitting, and the relatively low critical point (Pc = 73.8 bar, Tc = 31 °C) are particularly interesting for catalytic applications in chemical synthesis, over a wide range of temperatures and pressures. The benefits of coupling catalysis and supercritical fluids are both environmental and commercial: ...
Resource Upgrading in Advanced Supercritical Fluid (Supercritical Fluid with Catalyst and Cosolvent): Liquid Fuels from Biomass in Sub and Supercritical Water and Carbohydrate Up-Conversion in Ionic Liquid and Supercritical Fluids Mixtures. By Masaru Watanabe, Masayoshi Wagatsuma, Keisuke Suzuki, Takuma Kato, Yasuto Goto, Yukihiro Kanaguri and Yuya Hiraga. Liquid fuels from biomass and up-conversion of biomass in advanced supercritical fluid are reviewed in this chapter. Lignin can be converted into heavy hydrocarbons in subcritical water extraction. Lipid, which is triglyceride, is catalytically converted into straight-chain hydrocarbons of free fatty acid (decarboxylation) formed by hydrolysis. Carbohydrate is also hydrothermally converted into furan ring compound and fatty acids. Protein is converted into amino acids in hydrothermal water and depolymerization of protein is favored with rapid heating and denaturation agency such as alkaline earth metals. Free amino acids are further decomposed ...
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Idaho National Laboratory has nominated its supercritical/solid catalyst for biodiesel production from waste fats, oils and greases for the R&D 100 Awards. The lab also nominated medical imaging from better radioisotope production, and significantly improved gun sight optics. INL has won 41 R&D 100 Awards since 1986. The Supercritical/Solid Catalyst...
TY - JOUR. T1 - Supercritical hydrothermal synthesis and in situ organic modification of indium tin oxide nanoparticles using continuous-flow reaction system. AU - Lu, Jinfeng. AU - Minami, Kimitaka. AU - Takami, Seiichi. AU - Shibata, Masatoshi. AU - Kaneko, Yasunobu. AU - Adschiri, Tadafumi. PY - 2012/1/25. Y1 - 2012/1/25. N2 - ITO nanoparticles were synthesized hydrothermally and surface modified in supercritical water using a continuous flow reaction system. The organic modification of the nanoparticles converted the surface from hydrophilic to hydrophobic, making the modified nanoparticles easily dispersible in organic solvent. The addition of a surface modifier into the reaction system impacted the crystal growth and particle size as well as dispersion. The particle size was 18 nm. Highly crystalline cubic ITO with a narrow particle size distribution was obtained. The advantages of short reaction time and the use of a continuous reaction system make this method suitable for industrial ...
Supercritical fluid-assisted deposition of materials on substrates, such as semiconductor substrates for integrated circuit device manufacture. The deposition is effected using a supercritical fluid-based composition containing the precursor(s) of the material to be deposited on the substrate surface. Such approach permits use of precursors that otherwise would be wholly unsuitable for deposition applications, as lacking requisite volatility and transport characteristics for vapor phase deposition processes.
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The possibility of very rapid curing of heterogeneous materials and the formation of unique structure has been presented by many workers. Radiation processing, including microwave heating, is an economical and applicable method of physical and chemical modification of polymeric materials. Beneficial properties of composite materials have been obtained, especially for such polymers [1]. The electric field component of microwave radiation is responsible for dielectric heating mechanisms because it can cause molecular motion by either migration of ionic species or rotation of dipolar species. In this work, definition of the critical state will be revisited, occurrence of supercritical foaming documented, and paths of investigation proposed. INTRODUCTION A lot of attention has been paid in the last two decades to the use of supercritical fluids (SCF) for foaming thermoplastics. The supercritical state is usually defined as a fluid being held at a pressure and temperature above its critical ...
Selama dekade terakhir ionic liquids (ILs) merupakan pelarut alternatif baru dengan campuran (kation dan anion) memiliki sifat fisik dan sifat larutan yang spesifik dan telah terbukti sebagai substituen menjanjikan dari pelarut organik konvensional yang mudah terbakar, mudah menguap, dan beracun dalam berbagai proses. Dalam literatur dan penelitian, senyawa ini sering disebut pelarut ramah lingkungan. Namun, dalam beberapa tahun terakhir persepsi kehijauan berubah secara dramatis sebagai komunitas saintis yang mulai proaktif menilai resiko aplikasi bahan kimia berdasarkan pada seluruh siklus kehidupan. Aplikasi ILs dalam memisahkan komponen aktif dari tumbuhan obat dapat dilakukan dengan dibantu berbagai metode ekstraksi antara lain; heat refluks extraction (IL-HRE), microwave-assisted extraction (IL-MAE), ultrasound-assisted extraction (IL-UAE), IL-assisted ultrahigh pressure extraction (IL-UPE), supercritical fluid extraction (IL-SFE) dan negative-pressure cavitation-assisted extraction ...
Determination of methylmercury in sediments using supercritical fluid extraction and gas chromatography coupled with microwave-induced plasma atomic emission spectrometry ...
Fingerprint Dive into the research topics of Phase behavior of water-insoluble simvastatin drug in supercritical mixtures of chlorodifluoromethane and carbon dioxide. Together they form a unique fingerprint. ...
The processibility of 15 carbohydrates, more or less commonly used, was investigated as excipients in supercritical fluid drying. The focus was on the ability to produce amorphous powder, the stability of the powders towards crystallisation, and the residual water and ethanol content. The aqueous solutions were sprayed into a pressurised carbon dioxide-ethanol mixture flowing cocurrently through a coaxial two-fluid nozzle. The powder characteristics appeared to be influenced by the supersaturation level reached during the SCF-drying process and by the properties of the sugar species, such as water solubility and glass transition temperature, or the solution viscosities. The stability and the residual solvent content of a selected set of sugars and some mixtures were further analysed. The stability of amorphous powders was investigated at 4 degrees C, room temperature, 40 and 50 degrees C. Lactose, maltose, trehalose, raffinose, cyclodextrin, low-molecular-weight dextran and inulin could form ...
Supercritical fluid foaming of semi-crystalline natural-based polymers has been studied using ionic liquids as plasticizing agents, promoting hereafter foaming of the structures. Deep eutectic solvents (DES) are considered today a new generation ionic liquids. DES can be constituted by two natural primary metabolites, namely, aminoacids, organic acids, sugars or choline derivatives and are in this case called natural deep eutectic solvents (NADES). Furthermore, they can even be constituted by an active agent, such as ibuprofen, for example. In this work, we evaluate the possibility of dopping a natural-based polymer, particular a blend of starch and poly-e-carolactone (70:30) with different NADES. The polymers dopped with 10 wt% of each NADES were processed by compression moulding to obtain a homogeneous structure. The compressed mould specimens were tested in order to evaluate their mechanical properties, in tensile mode, and the results suggest that the presence of NADES was able to lower the ...
Are there hydrogen bonds in supercritical methanol and ethanol? Temperature and length scale dependence of tetraalkylammonium ion-amide interaction
Preparation of Active Proteins, Vaccines and Pharmaceuticals as Fine Powders using Supercritical or Near-Critical Fluids Journal Article ...
The ITER project design foresees Supercritical Helium (SHe) forced flow cooling for the main cryogenic components, namely, the superconducting (SC) magnets and cryopumps (CP). Therefore, cold circulators have been selected to provide the required SHe mass flow rate to cope with specific operating conditions and technical requirements. Considering the availability impacts of such machines, it has been decided to perform evaluation tests of the cold circulators at operating conditions prior to the series production in order to minimize the project technical risks. A proposal has been conceptualized, evaluated and simulated to perform representative tests of the full scale SHe cold circulators. The objectives of the performance tests include the validation of normal operating condition, transient and off-design operating modes as well as the efficiency measurement. A suitable process and instrumentation diagram of the test valve box (TVB) has been developed to implement the tests at the required ...
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PAN Czytelnia Czasopism, Increase of power and efficiency of the 900 MW supercritical power plant through incorporation of the ORC - Archives of Thermodynamics
Organix South, TheraNeem Organix, Supercritical Extract of Neem Leaf, Immunity and Skin Support, 30 Softgel Capsules $12.90. Neem, Homeopathy, Herbs. Herbal medicines are produced from plants and are based on traditional knowledge. Ayurveda play b...
The application of ultrasonic extraction,microwave extraction,supercritical CO2 extraction,macroporous adsorption resin and so on which researched in recent year in Rheum of purification were summarized.
ADM and the University of Illinois announced the successful completion of the Illinois Basin - Decatur Project (IBDP), a carbon capture and storage (CCS) project designed to evaluate and test the technology at commercial scale. This is one of two CCS projects located adjacent to ADMs corn processing plant in Decatur, Illinois.. Over three years approximately 1000 tonnes/day of carbon dioxide (CO2), obtained from ethanol production at the ADM plant, was compressed, dehydrated, sent along a 1.9-km pipeline, and injected into the Mt. Simon Sandstone 2.14 km deep in the Illinois Basin. Injection took place from 17 November 2011 to 26 November 2014, with 999,215 tonnes of supercritical CO2 injected and geologically stored.. Following injection completion, the IBDP effort conducted post-injection monitoring.. The IBDP developed and implemented a rigorous and extensive monitoring, verification, and accounting (MVA) program, including high-fidelity induced seismicity monitoring, 3-D seismic surveying, ...
To obtain the CBD-packed hemp extract from its organic crop, Highland Pharms uses a process called supercritical CO2 extraction. This method eliminates the need for more harmful solvents, while it also, the company says, yields CBD oil of an outstanding purity and efficacy. Those wanting to see for themselves can take their pick from Highland Pharms positively reviewed variety of tinctures - the strongest concentration of which measures up at 1,250 mg - as well as capsules and edibles. And if those potential customers have no idea exactly how much CBD they should be imbibing, then they can get themselves up to speed at the Texas-based companys website, which offers a user-friendly guide to serving sizes and methods of CBD oil intake, among other common queries. ...
QUELL Fish Oil is Supercritical CO2 extracted oils in triglyceride form, manufactured in Germany exclusively for Douglas Laboratories. QUELL Fish Oil is unique among other fish oils for its critical extraction, purity, bioavailability and concentrations ...
Abstract: Amorphous, low-porosity carbon spheres on the order of a few micrometers in size were prepared by carbonization of squalane (C30H62) in supercritical CO2 at 823 K. The spheres were characterized and used as catalysts supports for Pd. Near-edge X-ray absorption fine structure studies of the spheres revealed sp2 and sp3 hybridized carbon. To activate carbons for interaction with a metal precursor, often oxidative treatment of a support is needed. We showed that boiling of the obtained spheres in 28 wt % HNO3 did not affect the shape and bulk structure of the spheres, but led to creation of a considerable amount of surface oxygen-containing functional groups and increase of the content of sp2 hybridized carbon on the surface. This carbon was seen by scanning transmission electron microscopy in the form of waving graphene flakes. The H/C atomic ratio in the spheres was relatively high (0.4) and did not change with the HNO3 treatment. Palladium was deposited by impregnation with Pd acetate ...
Did you know these facts on CBD OIL and Full Spectrum CBD Hemp Oil? Cannabinoids are separated from hemp using supercritical CO2 extraction. Thanks to modern-day technology, the resulting solution is clean, without heavy metals and unneeded waxes, naturally present in the plant, and the sucked liquid has a typical, oily consistency. CBD oil includes cannabidiol as a base active ingredient and may contain just trace quantities of tetrahydroxycannabidiol (THC). Works as a memory enhancer, enhancing concentration and coordination of motions, getting rid of swelling and recurrent infections. It improves the conduction of stimuli in the course of autoimmune illness (several sclerosis, amyotrophic sclerosis). It is recommended by medical professionals and pharmacists as an antioxidant and compound that blocks the action of proinflammatory cytokines (proteins), e.g. in Crohns illness or ulcerative intestinal tract. RSO oil has a low CBD content, while high THC. The synergistic (enhancing) action of ...
Safer extraction strategies embody supercritical CO2 or food-grade ethanol. If you live in a state the place medical marijuana is authorized and available, look for CBD merchandise produced from excessive-resin hashish (rather than low-resin industrial hemp) that are sold in state-licensed dispensaries. CBD, on the other hand, receivedt get you excessive-but research means that it does have a variety of different well being-impacting properties. CBD oil is supposed to harness those well being advantages for those who need to deal with sure situations and illnesses, corresponding to anxiousness, utilizing a natural product. While the science behind CBDs effectiveness for treating anxiousness, pain, and insomnia is still in its infancy, Charlotte Figis inspiring story sounds promising.. There can also be an explainer about the difference between CBD merchandise produced from industrial hemp versus in a lab, and merchandise produced from the whole marijuana plant. You have in all probability ...
Hemplucid Whole-Plant™ CBD Wax contains 200mg of ultra-refined, full-spectrum CBD concentrate. We use a solvent-less supercritical CO2 extraction process that yields a golden yellow CBD wax that is rich in terpenes. The result is an amazingly effective product that is fast-acting and vastly more potent than the isolated CBD extracts youll find elsewhere.. This product is designed or use in a wax rig, or a modified vaporizer. Hemplucid Wax is not edible.. ...
In situ investigation of supercritical CO2 assisted impregnation of drugs into a polymer by generic viagra united states high pressure FTIR micro-spectroscopy. Patients who relapse following this approach are treated with cisplatin-based chemotherapy, with retroperitoneal lymph node dissection considered for patients with post-chemotherapy residual masses. Emergent surgery was performed due to sudden severe respiratory failure despite profound liver cirrhosis (Child-Pugh class B). Late transcription also requires an RNA polymerase core-binding co-activator.. The author in this article identifies two liberating discoveries that foster human flourishing: the potential of new knowledge and the importance of living gratitude. The combination of ribotyping and PFGE identified two large epidemic clones, which were called 691.5/PFGE-G and 595.7/PFGE-A. Because small colonic tumours may not be visualized or palpated during laparoscopy, location of generic viagra trusted pharmacy the lesion must be ...
The pK(a) of 3-acetamido-5-acetylfuran (3A5AF) was predicted to be in the range 18.5-21.5 by using the B3LYP/6-311+G(2d,p) method and several amides as references. The experimental pK(a) value, 20.7, was determined through UV/Vis titrations. Its solubility was measured in methanol-modified supercritical CO2 (mole fraction, 3.23×10(-4), cloud points 40-80 °C) and it was shown to be less soluble than 5-hydroxymethylfurfural (5-HMF). Dimerization energies were calculated for 3A5AF and 5-HMF to compare hydrogen bonding, as such interactions will affect their solubility. Infrared and (1) H nuclear magnetic resonance spectra of 3A5AF samples support the existence of intermolecular hydrogen bonding. The highest occupied molecular orbital, lowest unoccupied molecular orbital, and electrostatic potential of 3A5AF were determined through molecular orbital calculations using B3LYP/6-311+G(2d,p). The π-π* transition energy (time-dependent density functional theory study) was compared with UV/Vis data. ...
Ya Ling, Jian; Ying Zhang, Guo; Jie Cui, Zhao; Kai Zhang, Chang (2007). "Supercritical fluid extraction of quinolizidine ... and purification by high-speed counter-current chromatography" (PDF). Journal of Chromatography A. 1145 (1-2): 123-127. doi: ... by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry". Journal of Pharmaceutical and ...
"Supercritical fluid extraction of kava lactones from Piper methysticum (kava) herb". Journal of High Resolution Chromatography ... Pharmaceutical and herbal supplement companies extract kavalactones from the kava plant using solvents such as supercritical ... using high performance thin layer chromatography (HPTLC)". Food Chemistry. 151: 554-560. doi:10.1016/j.foodchem.2013.11.120. ...
... including high-performance liquid chromatography (HPLC), gas chromatography (GC), and supercritical fluid chromatography (SFC ... "Analysis of lipids from a hydrothermal vent methanogen and associated vent sediment by supercritical fluid chromatography". ... King, Jerry (2002-01-22), "Supercritical Fluid Technology for Lipid Extraction, Fractionation, and Reactions", Lipid ... To determine the concentration of archaeol present in a sample, chromatography technologies are commonly employed, ...
... have been detected in Yunnan Baiyao powder formulations through capillary supercritical fluid chromatography. Yunnan Baiyao ... of panaxadiol and panaxatriol in radix notoginseng and Yunnan baiyao by capillary supercritical fluid chromatography]". Yao Xue ...
D. Klink; O. Schmitz (2016). "SFC-APLI-(TOF)MS: Hyphenation of Supercritical Fluid Chromatography to Atmospheric Pressure Laser ... Couplings with separation methods like Supercritical Fluid Chromatography (SFC) and Chip-Electrospray (Chip-ESI) have also been ... Thiäner, Jan B.; Achten, Christine (2017-03-01). "Liquid chromatography-atmospheric pressure laser ionization-mass spectrometry ... in particular in applications with liquid chromatography (LC-MS) .The selectivity of APLI is one factor contributing to the ...
Nexera UC fully automated supercritical fluid extraction - supercritical fluid chromatography - mass spectrometry system; ... "Nexera UC Unified Chromatography - The Swiss Knife of analytics - SHIMADZU UK LIMITED". www.shimadzu.co.uk. waters. "Full ... AQUITY QDa mass detector for chromatography; Bronze - AB Sciex LLC - CESI-MS system using capillary electrophoresis combined ... 2003: Gold - Dionex Corp - ICS 2000 Reagent-Free ion chromatography system; Silver - Thermo Electron Corp - Finnigan LTQ hybrid ...
Linford has worked on topics including supercritical fluid chromatography and the formation of first alkyl monolayers on ... In his group they also undertake liquid chromatography (HPLC and TLC) and solid phase extraction (SPE), develop hydrophobic ... His lab is devoted towards synthesizing hydrophobic surfaces, diamond stationary phases for liquid chromatography and ...
"Supercritical Fluid Extraction and High-Performance Liquid Chromatography-Diode Array-Electrochemical Detection of Signature ...
... enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography ... THC and its 11-OH-THC and THC-COOH metabolites can be detected and quantified in blood, urine, hair, oral fluid or sweat using ... by reverse-phase high-performance liquid chromatography estimation. Ashton CH (February 2001). "Pharmacology and effects of ...
Keene P. Dimick Award in Chromatography, Third International Symposium on Supercritical Fluid Chromatography Award for ... supercritical fluid chromatography, and capillary electrophoresis. Additionally, he is highly acclaimed for his research in ... ACS Short Course on Supercritical Fluid Chromatography 1988, 1990 - Organizing Committee, International Symposium, "Microcolumn ... Tswett Award and Medal in Chromatography; American Chemical Society Award in Chromatography; ISCO Award in Biochemical ...
... supercritical fluid chromatography, laboratory informatics, rheometry and microcalorimetry. The business was started by James ( ... The company's first major break came when Dow Chemical bought one of Waters' first gel permeation chromatography instruments, ... Waters markets to the laboratory-dependent organization in these market areas: liquid chromatography, mass spectrometry, ... Empower chromatography and MassLynx mass spectrometry software, Oasis sample preparation products, NuGenesis lab management ...
Supercritical fluid chromatography[edit]. Main article: Supercritical fluid chromatography. Supercritical fluid chromatography ... or a supercritical fluid (supercritical-fluid chromatography, SFC). The mobile phase consists of the sample being separated/ ... Gas chromatography[edit]. Further information: Gas chromatography. Gas chromatography (GC), also sometimes known as gas-liquid ... Affinity chromatography[edit]. Further information: Affinity chromatography. Affinity chromatography[15] is based on selective ...
In 1984, he co-founded Lee Scientific to develop and market supercritical fluid chromatographic instrumentation and, in 1991, ... Tswett Chromatography Medal (1984), the Keene P. Dimick Chromatography Award (1988), the American Chemical Society Award in ... the Russian Tswett Chromatography Medal (1992), the Martin Gold Medal (1996), the Latin-American Chromatography Congress Medal ... He is a co-founder of Torion Technologies, which markets a hand-portable gas chromatography-mass spectrometry system. He is ...
... a curve whose ranges contain the entire 2-dimensional unit square Supercritical fluid chromatography, a form of normal phase ... chromatography Specific fuel consumption (disambiguation) Brake specific fuel consumption (BSFC), the fuel consumption of a ...
20 Test Method for Determination of Olefin Content of Gasolines by Supercritical-Fluid Chromatography D6551/D6551M - 05(2019) ... C by Gas Chromatography D6353 - 06(2017)e1 Guide for Sampling Plan and Core Sampling for Prebaked Anodes Used in Aluminum ... Ester Fluids Used in Electrical Apparatus D6873/D6873M - 19 Practice for Bearing Fatigue Response of Polymer Matrix Composite ... by Capillary Gas Chromatography D6145 - 97(2018) Guide for Monitoring Sediment in Watersheds D6146 - 97(2018) Guide for ...
... countercurrent or centrifugal partition chromatographies and Supercritical Fluid chromatography (SFC). It is commonly used for ... Ultra high-performance liquid chromatography (UHPLC), Purification liquid chromatography such as flash or preparative ... An evaporative light scattering detector (ELSD) is a detector used in conjunction with high-performance liquid chromatography ( ...
Guide for Supercritical Fluid Chromatography Terms and Relationships E1450 - 16 Test Method for Tension Testing of Structural ... Practice for Testing Flame Ionization Detectors Used in Gas or Supercritical Fluid Chromatography E595 - 15 Test Method for ... Guide for Purity of Carbon Dioxide Used in Supercritical Fluid Applications E1748 - 95(2017) Test Method for Evaluating the ... Practice for General Techniques of Liquid Chromatography-Infrared (LC/IR) and Size Exclusion Chromatography-Infrared (SEC/IR) ...
... column chromatography preparative-high performance liquid chromatography super critical fluid chromatography high speed counter ... chromatography a combination of vacuum flash silica gel chromatography and flash C8 column chromatography flash chromatography ...
... gas chromatography) UPLC (ultra performance liquid chromatography) Supercritical fluid chromatography Electrophoresis Ligand ... gas chromatography-mass spectrometry) LC-DAD (liquid chromatography-diode array detection) CE-MS (capillary electrophoresis- ... The first studies measuring drugs in biological fluids were carried out to determine possible overdosing as part of the new ... Initially, nonspecific assays were applied to measuring drugs in biological fluids. These were unable to discriminate between ...
Simulated distillation of high-boiling petroleum fractions by capillary supercritical fluid chromatography and vacuum thermal ... 7, 1992 The Scientist, June, 1990 Robert Brownlee Foundation Chromatography Forum. ... to form the Bay Area Chromatography Colloquium. Bob Stevenson is quoted as saying in his Nine Lives of the California ... a manufacturer of columns and pumps for high-performance liquid chromatography systems. Bob Brownlee took the initiative "along ...
15 Test Method for Determination of Olefin Content in Denatured Ethanol by Supercritical Fluid Chromatography D7348 - 13 Test ... Aromatic Hydrocarbons in Aviation Turbine Fuels and other Kerosene Range Fuels by Supercritical Fluid Chromatography D8308 - 20 ... by Gas Chromatography D7922 - 14 Test Method for Determination of Glycol for In-Service Engine Oils by Gas Chromatography D7923 ... and Biosolids by Pressurized Fluid Extraction and Analyzed by Liquid Chromatography/Tandem Mass Spectrometry D7859 - 19 ...
2009). "Investigation of supercritical fluid extraction of puerarin from Pueraria Lobata". Journal of Food Process Engineering ... Journal of Chromatography A. Elsevier. 923 (1-2): 255-262. doi:10.1016/S0021-9673(01)00996-7. PMID 11510548. Kintzios, Spiridon ...
... enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography ... Detection in body fluidsEdit. Main article: Cannabis drug testing. THC and its 11-OH-THC and THC-COOH metabolites can be ... by reverse-phase high-performance liquid chromatography estimation.. ... detected and quantified in blood, urine, hair, oral fluid or sweat using a combination of immunoassay and chromatographic ...
... carbon dioxide: Supercritical fluid chromatography, a form of liquid chromatography using supercritical carbon ... a Generation IV nuclear reactor concept that uses supercritical water as the working fluid Supercritical flow, where flow ... similar to freeze drying Supercritical fluid, a substance at a temperature and pressure above its thermodynamic critical point ... the bifurcation is called supercritical Pitchfork bifurcation, in mathematics, similar to Hopf bifurcation Super Critical, an ...
... chromatography (SFC) can be used on an analytical scale, where it combines many of the advantages of high ... Recent supercritical fluids have shown the capability to reduce particles up to a range of 5-2000 nm. Supercritical fluids act ... gases and supercritical fluids. In addition, there is no surface tension in a supercritical fluid, as there is no liquid/gas ... supercritical fluid water with a sheet of solid high pressure water ice at the bottom. The advantages of supercritical fluid ...
History of chromatography Supercritical fluid chromatography Berthod, Alain; Maryutina, Tatyana; Spivakov, Boris; Shpigun, Oleg ... Countercurrent chromatography (CCC, also counter-current chromatography) is a form of liquid-liquid chromatography that uses a ... Unlike column chromatography and high-performance liquid chromatography, countercurrent chromatography operators can inject ... Comparing multilayer toroidal coil chromatography with centrifugal partition chromatography". Journal of Chromatography A. 1218 ...
U.S.EPA Method 3560 Supercritical Fluid Extraction of Total Recoverable Hydrocarbons U.S.EPA Method 3561 Supercritical Fluid ... Journal of Chromatography A. 1152 (1-2): 234-246. doi:10.1016/j.chroma.2007.02.046. hdl:10261/12445. PMID 17353022. ... Supercritical CO 2 is used in certain industrial cleaning processes. Caffeine Dry cleaning Perfume Supercritical fluid Span, ... Yeo, S.; Kiran, E. (2005). "Formation of polymer particles with supercritical fluids: A review". J. Supercrit. Fluids. 34 (3): ...
... (SFC) is a form of normal phase chromatography that uses a supercritical fluid such as ... Taylor, Larry T. (2009). "Supercritical fluid chromatography for the 21st century". The Journal of Supercritical Fluids. 47 (3 ... "Integration of supercritical fluid chromatography into drug discovery as a routine support tool". Journal of Chromatography A. ... supercritical fluid chromatography is sometimes called convergence chromatography. SFC is used in industry primarily for ...
January 2015). "Optimization of supercritical fluid consecutive extractions of fatty acids and polyphenols from Vitis vinifera ... which are then separated by gas chromatography. or analyzed by gas chromatography and mid-infrared spectroscopy. Separation of ... This fatty acid composition results in a more fluid cell membrane but also one that is permeable to various ions (H+ & Na+ ), ... Other separation techniques include high-performance liquid chromatography (with short columns packed with silica gel with ...
"Supercritical fluid extraction of kava lactones from Piper methysticum (kava) herb". Journal of High Resolution Chromatography ... Pharmaceutical and herbal supplement companies extract kavalactones from the kava plant using solvents such as supercritical ... using high performance thin layer chromatography (HPTLC)". Food Chemistry. 151: 554-560. doi:10.1016/j.foodchem.2013.11.120. ...
"Optimization of Supercritical Fluid Consecutive Extractions of Fatty Acids and Polyphenols from Vitis Vinifera Grape Wastes". ... Jingren He, Celestino Santos-Buelga, Nuno Mateus and Victor de Freitas, Journal of Chromatography A, Volume 1134, Issues 1-2, ... Journal of Chromatography A. 874 (1): 101-9. doi:10.1016/S0021-9673(00)00086-8. PMID 10768504.. ...
High Performance Liquid Chromatography (HPLC), size exclusion chromatography, sarta supercritical fluid chromatography.[9][10] ... Size exclusion chromatography[besut , besut sumber]. Size exclusion chromatography, utawi ugi sami kaliyan gel permeation utawi ... High performance liquid chromatography[besut , besut sumber]. High performance liquid chromatography (HPLC) gadhah prinsip ... 1.1 Kromatografi Cair (Liquid Chromatography) *1.1.1 Reverse phase chromatography. *1.1.2 High performance liquid ...
In supercritical electric fields, the field strength overbears the surface tension and a fluid jet emanates from the droplet ... Many technical applications of biological objects like proteins, viruses or bacteria such as chromatography, optical ... Core shell fibers of nano particles with fluid cores and solid shells can be used to entrap biological objects such as proteins ...
The Journal of Supercritical Fluids. 129: 16-27. doi:10.1016/j.supflu.2017.03.014.. ... or more reliably by gas chromatography combined with mass spectrometry (GC/MS). Liquid chromatography (LC) techniques are also ... Supercritical solvent extraction with carbon dioxide is an alternative technique. Once extracted, isolated components can be ... Rovetto L, Aieta N (November 2017). "Supercritical carbon dioxide extraction of cannabinoids from Cannabis sativa L.". ...
January 2015). "Optimization of supercritical fluid consecutive extractions of fatty acids and polyphenols from Vitis vinifera ... In chemical analysis, fatty acids are separated by gas chromatography of methyl esters;[6] additionally, a separation of ... This fatty acid composition results in a more fluid cell membrane but also one that is permeable to various ions (H+ & Na+), ... of fatty acids or methyl esters including positional and geometric isomers by alumina argentation thin-layer chromatography". ...
"Optimization of Supercritical Fluid Consecutive Extractions of Fatty Acids and Polyphenols from Vitis Vinifera Grape Wastes". ... Liquid liquid extraction can be also performed or countercurrent chromatography. Solid phase extraction can also be made on C18 ... Phosphomolybdic acid is used as a reagent for staining phenolics in thin layer chromatography. Polyphenols can be studied by ... Concentration can be made by ultrafiltration.[72] Purification can be achieved by preparative chromatography. ...
Supercritical fluid extraction: A relatively new technique for extracting fragrant compounds from a raw material, which often ... Creating perfumes through reverse engineering with analytical techniques such as Gas chromatography-mass spectrometry (GC/MS) ... employs Supercritical CO2. Due to the low heat of process and the relatively nonreactive solvent used in the extraction, the ...
"Optimization of Supercritical Fluid Consecutive Extractions of Fatty Acids and Polyphenols from Vitis Vinifera Grape Wastes". ... Journal of Chromatography A. 1134 (1-2): 215-225. doi:10.1016/j.chroma.2006.09.011. PMID 16997314.. ... Journal of Chromatography A. 874 (1): 101-9. doi:10.1016/S0021-9673(00)00086-8. PMID 10768504.. ...
At this temperature and pressure CO2 is a supercritical fluid, with properties midway between a gas and a liquid. Caffeine ... To do so, many coffee companies choose to employ high-performance liquid chromatography to quantitatively measure how much ... ISBN 978-94-010-4947-4. Lee, S.; Park, M.K.; Kim, K.H.; Kim, Y.-S. (September 2007). "Effect of Supercritical Carbon Dioxide ... Food scientists have also turned to supercritical carbon dioxide as a means of decaffeination. Developed by Kurt Zosel, a ...
They key step is the use of supercritical fluid extraction to remove water from the gel while maintaining the gel structure, ... Porous silica Stöber materials have applications in catalysis and liquid chromatography due to their high surface area and ... Applying supercritical drying techniques, a Stöber silica aerogel with a specific surface area of 700 m2 g−1 and a density of ... One method to produce a silica aerogel uses a modified Stöber process and supercritical drying. The product appears translucent ...
The Journal of Supercritical Fluids. 117: 89-97. doi:10.1016/j.supflu.2016.05.027. De Vincenzi, M.; Stammati, A.; De Vincenzi, ... ISBN 0-471-59374-5. Zawirska-Wojtasiak, R.; Mildner-Szkudlarz, S.; Wąsowicz, E.; Pacyński, M. (2010). "Gas chromatography, ... Vladić, J.; Zeković, Z.; Jokić, S.; Svilović, S.; Kovačević, S.; Vidović, S. (November 2016). "Winter savory: Supercritical ... "Characterization of volatile compounds from ethnic Agave alcoholic beverages by gas chromatography-mass spectrometry". Food ...
The product of this process is called a "concrete." Supercritical fluid extraction: A relatively new technique for extracting ... Creating perfumes through reverse engineering with analytical techniques such as Gas chromatography-mass spectrometry (GC/MS) ... fragrant compounds from a raw material, which often employs Supercritical CO2. Due to the low heat of process and the ...
Secondary ion mass spectrometry Supercritical fluid chromatography (SFC) Transmission electron microscopy (TEM) Titration ... Gas chromatography (GC) Gas chromatography-mass spectrometry (GC-MS) Gas chromatography-IR spectroscopy (GC-IR) Gel permeation ... chromatography-IR spectroscopy (GPC-IR) High performance liquid chromatography (HPLC) High performance liquid chromatography-IR ... Liquid chromatography-IR spectroscopy (LC-IR) Liquid chromatography-mass spectrometry (LC-MS) Mass spectrometry (MS) Mössbauer ...
The Journal of Supercritical Fluids. 173: 105218. doi:10.1016/j.supflu.2021.105218. ISSN 0896-8446. "Phytates in cereals and ... ISBN 978-1-56676-867-2.[page needed] Phillippy BQ, Bland JM, Evens TJ (January 2003). "Ion chromatography of phytate in roots ...
Elutriation Evaporation Extraction Leaching Liquid-liquid extraction Solid phase extraction Supercritical fluid extraction ... chromatography Affinity chromatography Centrifugal partition chromatography Gas chromatography and Inverse gas chromatography ... Countercurrent chromatography (CCC) Droplet countercurrent chromatography (DCC) Paper chromatography Ion chromatography Size- ... High-performance liquid chromatography (HPLC) Thin-layer chromatography (TLC) ...
... all distinction between phases disappears and the substance becomes a supercritical fluid. crystal A solid whose constituent ... gas chromatography A type of chromatography commonly used in analytical chemistry to isolate and analyze chemical compounds ... The fluid and small particles which successfully pass through the filter are called the filtrate. first-order reaction flask A ... Gas chromatography is often used to test the purity of substances, to identify unknown substances, and to measure the relative ...
When speciation of the organics is required for troubleshooting or design purposes, liquid chromatography-organic carbon ... sub and super critical boilers), and specialty applications such as research laboratories. The "ultrapure water" term became ... or as make-up to cooling fluid in some critical applications. UPW is even sometimes used as a humidification source for the ... and super critical oxidation. Typical equations showing persulfate generation of hydroxyl radicals follows. S2O8-2 + hν (254 nm ...
There are different tacit understandings of supercritical fluids. For example, "a fluid is considered to be 'supercritical' ... adsorption from supercritical gases in extraction processes and chromatography. Besides, knowledge of gas/solid interface ... Supercritical adsorption also referred to as the adsorption of supercritical fluids, is the adsorption at above-critical ... Fabrication of block copolymer monolayers by adsorption from supercritical fluids: A versatile concept for modification and ...
... chromatography (specifically adsorption chromatography, the first chromatography method) Alexei Tupolev (1925-2001), Russia - ... Supercritical airfoil, Winglet Eli Whitney (1765-1825), U.S. - the cotton gin Frank Whittle (1907-1996), UK - co-inventor of ... Correction fluid, Liquid Paper Iréne Grahn (1945-2013), Sweden - finger joint support for patients with rheumatoid arthritis ...
Supercritical fluid chromatography (SFC) is a form of normal phase chromatography that uses a supercritical fluid such as ... Taylor, Larry T. (2009). "Supercritical fluid chromatography for the 21st century". The Journal of Supercritical Fluids. 47 (3 ... "Integration of supercritical fluid chromatography into drug discovery as a routine support tool". Journal of Chromatography A. ... supercritical fluid chromatography is sometimes called convergence chromatography. SFC is used in industry primarily for ...
The use of supercritical fluids in analytical chemistry is still grow- ing. More and more analysts are discovering the ... Analytical Chemistry Chromatographie Chromatography Extraction Extraktion (Chem.) Supercritical Fluids chemistry Editors and ... Supercritical fluid chromatography (SFC) has become better established and the development of this technique has been ... Stationary Phases for Packed Column Supercritical Fluid Chromatography Colin F. Poole, John W. Oudsema, Thomas A. Dean, Salwa K ...
Japan Supercritical Fluid Chromatography (Sfc) Industry Market Research Report 2017. India Supercritical Fluid Chromatography ( ... Global Supercritical Fluid Chromatography (Sfc) Industry Market Research Report 2017. China Supercritical Fluid Chromatography ... United States Supercritical Fluid Chromatography (Sfc) Industry Market Research Report 2017. News • Feb 27, 2017 01:54 GMT ... The United States Supercritical Fluid Chromatography (Sfc) Industry Market Research Report 2017 is a professional and in-depth ...
The basic principles of liquid chromatography can be applied to supercritical fluid chromatography (SFC). ... Although supercritical fluid chromatography (SFC) is not a new technique, preparative SFC is becoming increasingly more popular ... Supercritical fluid chromatography can be run at increased flow rates making isolations faster and increasing throughput. ... Basic principles for the separation of compounds from mixtures using supercritical fluid chromatography (SFC) are similar to ...
USA Home > Product Directory > Analytical/Chromatography > HPLC > SFC (Supercritical Fluid Chromatography) Columns > GreenSep ...
Supercritical fluid chromatography columns. We provide preparative chromatography columns adapted to the high pressure ... SupersepTM , Supercritical fluid chromatography systems. Our Supersep™ preparative SFC systems enable fast, robust, ... Your process is greener thanks to the use of supercritical CO2 decreasing the amount of organic solvent required by 5 to 20 ...
The European Supercritical fluid chromatography reagents report defines and segments the concerned market in Europe with ... In super critical fluid chromatography, a supercritical fluid is used as the mobile phase. A super critical fluid is a ... North America Super Critical Fluid Chromatography (Reagents) Market Super Critical Fluid Chromatography Reagents-North America ... Europe is the second-largest market for supercritical fluid chromatography reagents. The demand for the supercritical fluid ...
46] Liu Y. Fluid and supercritical CO 2 as eluent in metal chelate chromatography. [52] Jentoft RE. Vazquez MJ. J Chromatogr ... Fifth International Symposium on Supercritical Fluid Chromatography and Extraction. Trends Anal Chem 1994. Packed-column ... Abstract Supercritical fluid chromatography (SFC) combines the high diffusion coefficients of gas chromatography (GC) and the ... fluid chromatography. Homogeneous catalysis in supercritical fluids. Journal of Chromatography. Caruso JA. Vela NP. Selby M. ...
Chromatography Data System. ChromNAV Ver. 2. *1 Stop valve unit *2 Solvent switching unit *3 Mixing unit *4 10 position-11port ... 2. M. Bounoshita, T. Kanomata, CHROMATOGRAPHY, 2011, 32, 23-32.. 3. O. A. Adegoke, Afr.J. Pure Appl.Chem., 2012, 6 (14), 129- ... Ms Iijima is a member of the chromatography separations team at JASCO Corporation main applications laboratory in Tokyo Japan. ... "Practical High-Performance Liquid Chromatography", 4th ed., John Wiley & Sons , 2004, 92 and 279-282. ...
nterest in supercritical fluid chromatography (SFC) applications is growing due to its ability to reduce analysis times, ... Rapid Peptide Separation by Supercritical Fluid Chromatography with Mass Spectrometry. By DJ Tognarelli ... Home / Applications / Rapid Peptide Separation by Supercritical Fluid Chromatography with Mass Spectrometry ... The separation column was a Princeton Chromatography 2-Ethylpyrindine column (4.6 mm ID x 250 mm L, 5 mm, 60A). The standard 5 ...
Supercritical Fluid Chromatography (SFC). E-BooksWebcasts. Resources. ProductsChromTubeEventsPodcastsSponsored VideosQ&As ... Liquid Chromatography (LC/HPLC)Gas Chromatography (GC)Sample PreparationMass SpectrometryPharmaceutical AnalysisEnvironmental ... View MoreLiquid Chromatography (LC/HPLC)Gas Chromatography (GC)Sample PreparationMass SpectrometryPharmaceutical Analysis ... and advantages of using SFC as it relates to analytical and preparative chromatography. ...
In this report, the United States Supercritical Fluid Chromatography (SFC)... ... 104 Pages Report] Check for Discount on United States Supercritical Fluid Chromatography (SFC) System Market Report 2017 report ... United States Supercritical Fluid Chromatography (SFC) System Market Report 2017. 1 Supercritical Fluid Chromatography (SFC) ... 7 Supercritical Fluid Chromatography (SFC) System Manufacturing Cost Analysis. 7.1 Supercritical Fluid Chromatography (SFC) ...
... supercritical fluid chromatography, capillary electrophoresis, thin-layer chromatography and high pressure liquid ... 23rd Montreux Symposium on Liquid Chromatography-Mass Spectrometry, Supercritical Fluid Chromatography-Mass Spectrometry, ... Development and application of supercritical fluid extraction-immunoaffinity chromatography procedure Bou Carrasco, Pilar; Díez ... Sample records for CROMATOGRAFIA DE FLUIDO SUPERCRITICO (supercritical fluid chromatography). from WorldWideScience.org. Sample ...
... the only company worldwide providing supercritical fluid chromatography (SFC) systems spanning from analytical to preparative ... Thar Technologies, Inc., the only company worldwide providing supercritical fluid chromatography (SFC) systems spanning from ... Thar Technologies, Inc., the only company worldwide providing supercritical fluid chromatography (SFC) systems spanning from ... Supercritical Fluid Chromatography (SFC). E-BooksWebcasts. Resources. ProductsChromTubeEventsPodcastsSponsored VideosQ&As ...
Supercritical Fluid Chromatography (SFC) received an uneasy welcome, mainly because of the lack of commercially available ... the application to chromatography of the critical phenomena of compressed gases or overheated liquids as supercritical fluids ... Extraction with supercritical fluids (SFs) was welcome from the very beginning. In the present paper, ... High-Performance Liquid Chromatography or even Thin Layer Chromatography. The present status and future perspectives for SFC ...
Read reviews and compare manufacturers of Supercritical Fluid Chromatography > Accessories products in the SelectScience ... such as supercritical fluid chromatography (SFC), HPLC, supercritical fluid extraction (SFE), particle formation, reactions, so ... gas chromatography. Refillable moisture traps are constructed from ... Read more... ...
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"Selectivity in Tuning in Packed Column Supercritical Fluid Chromatography." Supercritical Fluid Chromatography with Packed ... "Selectivity in Tuning in Packed Column Supercritical Fluid Chromatography." Supercritical fluid chromatography with packed ... Selectivity in tuning in packed column supercritical fluid chromatography. Supercritical fluid chromatography with packed ... Selectivity in tuning in packed column supercritical fluid chromatography. Supercritical fluid chromatography with packed ...
Supercritical fluid chromatography (SFC) coupled with triple quadrupole mass spectrometry was applied to the profiling of ... as compared to the conventional high-performance liquid chromatography. The applicability of our method for the analysis of SEs ...
Journal of chromatography. A 2014-12-3 Comparison of liquid chromatography and supercritical fluid chromatography coupled to ... and ultra-high performance supercritical fluid chromatography (UHPSFC)) were tested in combination with simple MS detector. To ... At the end, the proposed strategy of optimized chromatography combined with simple MS device has been shown to potentially ... For this purpose, two modern chromatographic approaches (ultra-high pressure liquid chromatography (UHPLC) ...
In this report, the United States Supercritical Fluid Chromatography (Sfc)... ... 98 Pages Report] Check for Discount on United States Supercritical Fluid Chromatography (Sfc) Market Report 2017 report by ... 1 Supercritical Fluid Chromatography (Sfc) Overview. 1.1 Product Overview and Scope of Supercritical Fluid Chromatography (Sfc) ... 7 Supercritical Fluid Chromatography (Sfc) Manufacturing Cost Analysis. 7.1 Supercritical Fluid Chromatography (Sfc) Key Raw ...
Separation of coenzyme Q10 in CPO and palm fibre oil was carried out using supercritical fluid chromatography with ultra violet ... Separation of Coenzyme Q10 in Palm Oil by Supercritical Fluid Chromatography Ng M. Han, Choo Y. May, Ma A. Ngan, Chuah C. Hock ... Separation of coenzyme Q10 in CPO and palm fibre oil was carried out using supercritical fluid chromatography with ultra violet ...
Supercritical fluid chromatography (SFC) is a separation method that uses supercritical carbon dioxide as the mobile phase. Due ... CO2 cylinders used for SFC are filled with supercritical carbon dioxide generated by industrial plants, meaning that no new ...
... and one esterified form of α-tocopherol acetate were analyzed using ultra-high-performance supercritical fluid... ... Ultra-High-Performance Supercritical Fluid Chromatography. The ultra-high-performance supercritical fluid chromatography system ... Ultra-high-performance supercritical fluid chromatography Ultra-high-performance liquid chromatography Liquid-liquid extraction ... Oberson JM, Campos-Gimenez E, Riviere J, Martin F (2018) Application of supercritical fluid chromatography coupled to mass ...
Supercritical Fluid Chromatography Introduction: Supercritical Fluid Chromatography (SFC) is a hybrid of gas and liquid ... Supercritical Fluid Chromatography Introduction : Supercritical Fluid Chromatography (SFC) is a hybrid of gas and liquid ... 421-821-chapter-29-30 - Supercritical Fluid Chromatography.... This preview shows document pages 1 - 5. Sign up to view the ... chromatography that combines some of the best features of both Supercritical Fluid exist at temperatures and pressures above ...
Quantification of 3-n-butylphthalide in beagle plasma samples by supercritical fluid chromatography with triple quadruple mass ... Quantification of 3-n-butylphthalide in beagle plasma samples by supercritical fluid chromatography with triple quadruple mass ... A high-throughput, rapid, sensitive, environmentally friendly, and economical supercritical fluid chromatography with triple ... The mobile phase comprised supercritical carbon dioxide/methanol (90:10, v/v) at a flow rate of 1.5 mL/min, the compensation ...
The differences in matrix effects between supercritical fluid chromatography and reversed phase liquid chromatography coupled ... The increasing popularity of supercritical fluid chromatography (SFC) in combination with electrospray ionization mass ...
... fluid extraction of pesticides in sediment from the Okavango Delta, Botswana, and determination by gas chromatography with ... Fluid. 31 (2) 149-157. [ Links ]. REVERCHON E and DE MARCO I (2006) Supercritical fluid extraction of natural matter. J. ... Fluid. 38 (2) 167-180. [ Links ]. CAMEL V (1998) Supercritical fluid extraction as a useful method for pesticides determination ... QUAN C. LI S, TIAN S, XU H, LIN A and GU L (2004) Supercritical fluid extraction and clean-up of organochlorine pesticides in ...
Comprehensive and off-line supercritical fluid chromatography: reversed phase liquid chromatography for the analysis of complex ... "Comprehensive and Off-line Supercritical Fluid Chromatography: Reversed Phase Liquid Chromatography for the Analysis of Complex ... "Comprehensive and Off-line Supercritical Fluid Chromatography: Reversed Phase Liquid Chromatography for the Analysis of Complex ... Comprehensive and off-line supercritical fluid chromatography: reversed phase liquid chromatography for the analysis of complex ...
  • Thar designs and manufactures high pressure pumps ideally for high pressure and high temperature applications, such as supercritical fluid chromatography (SFC), HPLC, supercritical fluid extraction (SFE), particle formation, reactions, so. (selectscience.net)
  • The low viscosity of supercritical fluids enables 3-5 times higher flow rates compared to HPLC, with increased efficiencies due to the higher diffusivity of analytes in a CO2 based mobile phase. (chromatographytoday.com)
  • Read online Supercritical Fluid Chromatography And Micro hplc written by M. Yoshioka, published by VSP which was released on 1989. (ebooksdownloads.xyz)
  • Download full Supercritical Fluid Chromatography And Micro hplc Books now! (ebooksdownloads.xyz)
  • Waters Corporation is a global leader in liquid chromatography (UPLC/HPLC), mass spectrometry (MS), rheology and thermal analysis. (chemeurope.com)
  • VICI is an international company with over 40 years experience of manufacturing high quality products (valves, detectors and accessories) for gas chromatography (GC), liquid chromatography (HPLC, UHPLC), flow injection analysis (FIA), SFE and SFC. (chemeurope.com)
  • Pentafluorophenyl-bonded silica (PFP) phases employed in high-performance liquid chromatography (HPLC) often provide very different results depending on the column manufacturer. (usda.gov)
  • Bioanalytical characterization of the resulting powders involved spectrophotometry, sodium dodecyl sulfate-polycrylamide gel electrophoresis, reverse-phase high performance liquid chromatography (RP-HPLC), and size exclusion chromatography. (diva-portal.org)
  • The separation of isomeric compounds that are usually challenging for high.performance liquid chromatography (HPLC) can be accomplished by SFC . (musc.edu)
  • High-performance liquid chromatography (HPLC) and related techniques (M. Gazdag). (elsevier.com)
  • The vendors that responded to the survey with high performance liquid chromatography (HPLC) and ultrahigh-pressure liquid chromatography (UHPLC) columns are listed in Table I. The product range is highly varied from traditional reversed-phase columns using fully porous materials to columns designed for alternate separation technologies such as supercritical fluid chromatography (SFC). (chromatographyonline.com)
  • In this report, supercritical fluid chromatography replaces HPLC as the desalting/separation technique prior to mass analysis, providing a dramatic reduction in back-exchange compared to the fast, cold HPLC methods. (utmb.edu)
  • High-pressure liquid chromatography, also called high performance liquid chromatography (HPLC), is now widely used in industry. (encyclopedia.com)
  • A variation on HPLC is super-critical fluid chromatography (SFC). (encyclopedia.com)
  • Solvent costs are also generally lower than for high-performance liquid chromatography (HPLC). (wikipedia.org)
  • GONÇALVES C, CARVALHO JJ, AZENHA MA and ALPENDURA MF (2006) Optimisation of supercritical fluid extraction of pesticide residues in soil by means of central composite design and analysis by gas chromatography-tandem mass spectrometry. (scielo.org.za)
  • Supercritical fluid chromatography/tandem mass spectrometry (SFC/MS/MS) with methylation was used for the simultaneous profiling of diverse polar lipids in a mixture. (elsevier.com)
  • Waters Corp.'s new Acquity TQD puts the power of Ultra Performance Liquid Chromatography/Tandem Mass Spectrometry (UPLC/MS/MS) into the hands of chromatographers. (pharmamanufacturing.com)
  • Quantitative analysis of vitamin D and its main metabolites in human milk by supercritical fluid chromatography coupled to tandem mass spectrometry. (bvsalud.org)
  • Final extracts are derivatized with 4-phenyl-1,2,4-triazoline-3,5-dione and vitamin D derivatives analyzed by supercritical fluid chromatography hyphenated to tandem mass spectrometry with atmospheric pressure chemical ionization. (bvsalud.org)
  • Since the introduction of Liquid Chromatography-Tandem Mass Spectrometry (LC/MS/MS) into the clinical research laboratory over a decade ago, it has widely become accepted as the technique of choice for specific and accurate quantitation of many clinically relevant molecules in complex biological matrices. (separationsnow.com)
  • Selectivity in tuning in packed column supercritical fluid chromatography. (ugent.be)
  • Sandra P, MEDVEDOVICI A, KOT A, David F. Selectivity in tuning in packed column supercritical fluid chromatography. (ugent.be)
  • Packed-column supercritical fluid chromatography (pSFC) with detection using atmospheric pressure chemical ionisation (APCI) mass spectrometry (MS) provides a versatile method for the detection and quantification of 20 polymer additives, including common antioxidants, light stabilisers and slip agents. (semanticscholar.org)
  • The many faces of packed column supercritical fluid chromatography--a critical review. (semanticscholar.org)
  • This paper presents a novel Flame Ionization Detector (FID) capable of remaining lit at the high gaseous flow rates associated with Packed Column Supercritical Fluid Chromatography (pSFC) mobile phase decompression. (ucalgary.ca)
  • Supercritical fluid extraction coupled to packed column supercritical fluid chromatography. (booktopia.com.au)
  • The operator uses software to set mobile phase flow rate, co-solvent composition, system back pressure and column oven temperature which must exceed 40 °C for supercritical conditions to be achieved with CO2. (wikipedia.org)
  • Large volumes of solvents like methanol can limit the mass capacity of the column due to strong solvent effects that can distort the chromatography. (waters.com)
  • Major advantages of extracting metal species using supercritical CO 2 include minimization of waste solvent generation and direct removal of analytes from solid samples. (scribd.com)
  • nterest in supercritical fluid chromatography (SFC) applications is growing due to its ability to reduce analysis times, organic solvent consumption and waste production. (jascoinc.com)
  • Polar organic solvent chromatography. (semanticscholar.org)
  • Supercritical carbon dioxide (CO2) is well established for use as a processing solvent in polymer applications such as polymer modification, formation of polymer composites, polymer blending, microcellular foaming, particle production and polymerization. (scribd.com)
  • The nanotubes were further submitted to an extraction process using supercritical CO 2 as solvent. (scielo.br)
  • Carbon dioxide is a non-polar solvent once pressurised into a liquid or supercritical state. (york.ac.uk)
  • Furthermore, supercritical carbon dioxide becomes a gas at ambient temperature and pressure, so the processing for fractionation of separated components is simple, and has the advantage of using less organic solvent compared, for example, to liquid chromatography (LC) and allowing the environmental impact and cost to be reduced. (justia.com)
  • Stationary phases, solvent strength and buffers types will be addressed with respect to their unique impact on hydrophilic interaction chromatography, as well as advantages and disadvantages to the technique. (separationsnow.com)
  • Ionic liquids can form biphasic solvent systems with many organic solvents and water, and these solvent systems can be used in liquid-liquid separations and countercurrent chromatography. (springer.com)
  • In comparison to column chromatography, flows and total solvent usage can in most countercurrent chromatography separations may be reduced by half and even up to a tenth. (wikipedia.org)
  • Shimadzu Scientific Instruments released several technical reports for liquid chromatography-mass spectrometry (LCMS), including research on artificial colorants, polymer additives and nutraceuticals. (environmental-expert.com)
  • The following methods of resolution of enantiomers are considered: supercritical fluid chromatography, capillary electrophoresis, thin-layer chromatography and high pressure liquid chromatography using phases and/or chiral additives. (worldwidescience.org)
  • Key players in the European Super Critical Fluid Chromatography Reagents Market are Agilent Technologies, GE Healthcare, Helena Laboratories, Phenomenex, Inc., Thermo Fischer Scientific, W. R. Grace & Co., Waters Corporation & others. (prweb.com)
  • The super critical fluid chromatography reagents market in Europe was valued at $46.0 million in 2013, and is estimated to grow to $75.4 million by 2018, at a CAGR of 10.4% from 2013 to 2018. (prweb.com)
  • Super Critical Fluid Chromatography Reagents-North America can be segmented by Companies, Applications, Products, Processes, MacroIndicators and Endusers. (prweb.com)
  • Companies of Super Critical Fluid Chromatography Reagents-North America are Agilent Technologies, Phenomenex, Inc., GE Healthcare, W.R. Grace & Co., Helena Laboratories, Thermo Fisher Scientific, Waters Corporation and Other Companies. (prweb.com)
  • Applications of Super Critical Fluid Chromatography Reagents-North America are Analytical Chromatography Reagents and Preparative Chromatography Reagents. (prweb.com)
  • Products of Super Critical Fluid Chromatography Reagents-North America are Column Chromatography Reagents and Planar Chromatography Reagents. (prweb.com)
  • Processes of Super Critical Fluid Chromatography Reagents. (prweb.com)
  • Reversed-phase screening strategies for liquid chromatography on polysaccharide-derived chiral stationary phases. (semanticscholar.org)
  • Effects of mobile phase composition and temperature on the supercritical fluid chromatography enantioseparation of chiral fluoro-oxoindole-type compounds with chlorinated polysaccharide stationary phases. (semanticscholar.org)
  • The majority of published enantiomeric separations by supercritical fluid chromatography (SFC) utilize chiral stationary phases (CSP) based on chemically derivatized amylose or cellulose, coated or immobilized on silica. (usda.gov)
  • In this work, phosphatidylcholine, phosphatidyl-ethanolamine, phosphatidylinositol and phosphatidylserine have been studied by supercritical fluid chromatography (SFC) coupled with evaporative light scattering detection (ELSD) and mass spectrometry (MS). Four different silica-based stationary phases were studied: 2-ethylpyridine, 4-ethylpyridine, diol and conventional cyanopropyl. (vt.edu)
  • By contrast, in liquid-liquid chromatography, both the mobile and stationary phases are liquid. (wikipedia.org)
  • The countercurrent chromatography instrument is easily switched between normal phase chromatography and reversed-phase chromatography simply by changing the mobile and stationary phases. (wikipedia.org)
  • The product segment comprises planar chromatography reagent and column chromatography reagent, while the process segment consists of adsorption chromatography reagent, ion exchange chromatography reagent, size exclusion chromatography reagent, affinity chromatography reagent, and partition chromatography reagent which are discussed in the report. (prweb.com)
  • Hydrostatic instruments are marketed under the name centrifugal partition chromatography (CPC). (wikipedia.org)
  • Small-molecule reversed-phase columns, hydrophilic-interaction chromatography (HILIC) columns, and chiral columns continue to surface and are thus discussed separately. (chromatographyonline.com)
  • Chromatography is a versatile technique that can be used to carry out complicated separations like amino acid sequencing or relatively simple ones such as separating pollutants in the air. (prweb.com)
  • The Prep SFC 360 system represents a powerful solution for preparative separations by means of supercritical fluid chromatography. (norlab.com)
  • Chiral separations in normal-phase liquid chromatography: Enantioselectivity of recently commercialized polysaccharide-based selectors. (semanticscholar.org)
  • Coupled supercritical fluid extraction - capillary supercritical fluid chromatography. (booktopia.com.au)
  • For this purpose, two modern chromatographic approaches (ultra-high pressure liquid chromatography (UHPLC) and ultra-high performance supercritical fluid chromatography (UHPSFC)) were tested in combination with simple MS detector. (sigmaaldrich.com)
  • Nine tocopherol derivatives including four tocopherols, four tocotrienols, and one esterified form of α-tocopherol acetate were analyzed using ultra-high-performance supercritical fluid chromatography (UHPSFC) with diode array detection. (springer.com)
  • PIC-SFC is a leader in preparative supercritical fluid chromatography (SFC). (cannabizjournal.com)
  • The target components were separated and prepared by semi-preparative supercritical fluid chromatography . (bvsalud.org)
  • In this series of papers, we aim to provide some insight into the retention and separation mechanisms occurring in enantioselective supercritical fluid chromatography (SFC). (usda.gov)
  • abstract = "The ring-opening polymerization of (R,S)-β-butyrolactone (BL) in bulk was analyzed with respect to the polymer structure of the resulting poly[(R,S)-3-hydroxybutanoate)] [P(3HB)] by isolation of the pure form using preparative supercritical CO2 fluid chromatography. (elsevier.com)
  • Supercritical fluid chromatography (SFC) is a form of normal phase chromatography that uses a supercritical fluid such as carbon dioxide as the mobile phase. (wikipedia.org)
  • In recent years, supercritical fluid chromatography (SFC), which uses a supercritical fluid for the mobile phase, has attracted attention for separation and analysis of samples. (justia.com)
  • The purpose of preparative chromatography is to separate the components of a mixture for later use, and is thus a form of purification . (wikipedia.org)
  • Supercritical fluid chromatography for analysis and purification in drug discovery. (semanticscholar.org)
  • This article describes a supercritical fluid chromatography (SFC) process for separating a polypeptide from a mycelial extract, in this case, the purification of cyclosporin A obtained by fermentation. (vtt.fi)
  • A form of normal phase chromatography that is used for the analysis and purification of low to moderate molecular weight, thermally labile molecules. (contractpharma.com)
  • This work is a study of purification of SWCNT by heat treatment in an inert atmosphere followed by supercritical fluid extraction. (scielo.br)
  • Concentration and 1987 greater purification by sweep co-distillation omentum) and Florisil/anhydrous sodium sulfate column chromatography. (cdc.gov)
  • Chromatography is a physical method of separation that distributes components to separate between two phases, one stationary (stationary phase), the other (the mobile phase) moving in a definite direction. (wikipedia.org)
  • Macrocyclic and Hydroxamate Phases for Chromatography. (ucc.ie)
  • In the mid-1970s, interest in liquid mobile phases for column chromatography resurfaced when it was discovered that the efficiency of separation could be vastly improved by pumping the liquid through a short packed column under pressure, rather than allowing it to flow slowly down a vertical column by gravity alone. (encyclopedia.com)
  • In its broadest sense, countercurrent chromatography encompasses a collection of related liquid chromatography techniques that employ two immiscible liquid phases without a solid support. (wikipedia.org)
  • Some types of countercurrent chromatography, such as dual flow CCC, feature a true countercurrent process where the two immiscible phases flow past each other and exit at opposite ends of the column. (wikipedia.org)
  • In particular, the relatively recently developed solution-enhanced dispersion by supercritical fluids (SEDS) technology has been employed in the preparation of particles/powders. (diva-portal.org)
  • The principal method used for the detection of diazinon or its metabolites in biological samples is gas chromatography (GC) using a flame photometric detector (FPD), a mass spectroscopy detector (MS), an electron capture detector (ECD), or a flame ionization detector (FID). (cdc.gov)
  • The properties of supercritical fluids will be surveyed, with emphasis on their chromatographic properties. (pacslabs.com)
  • While supercritical fluid chromatography (SFC) has been available for decades , very few labs have chosen to take advantage of its remarkable chromatographic properties . (musc.edu)
  • Supercritical fluid extraction and high performance liquid chromatographic determination of benzopyrans and phloroglucinol derivative in Hypericum polyanthemum. (nextbio.com)
  • With supercritical carbon dioxide as the mobile phase,the effect of six factors, such as type of chromatographic columns,modifiers and modifiers ratio, flow rate of mobile phase, pressure and temperature , on the separation process of supercritical fluid chromatography were explored. (bvsalud.org)
  • High performance liquid chromatography and nuclear magnetic resonance were used to analyze the components and study the thermodynamic regularity of the chromatographic process. (bvsalud.org)
  • Supercritical fluid chromatography (SFC) coupled with triple quadrupole mass spectrometry was applied to the profiling of sucrose fatty acid esters (SEs). (go.jp)
  • Because the supercritical phase represents a state in which liquid and gas properties converge, supercritical fluid chromatography is sometimes called convergence chromatography. (wikipedia.org)
  • In this study, for the first time, convergence chromatography was used to measure thiols in red wine at ultratrace levels with improved sensitivity compared to previous methods. (mdpi.com)
  • Early development of supercritical fluid chromatography (SFC) was described as high-pressure or dense gas chromatography (HPGC or DGC) and low boiling point hydrocarbons were used as the supercritical mobile phase. (intlabsnet.com)
  • We provide preparative chromatography columns adapted to the high pressure requirement of SFC. (novasep.com)
  • Patrick Sandra UGent , A MEDVEDOVICI , A KOT and Frank David ( 1999 ) Supercritical fluid chromatography with packed columns . (ugent.be)
  • Typically, methods utilize reversed-phase chromatography which can result in a small but significant number of compounds not retained by C18 stationary phase columns due to the highly polar nature of some compounds. (intlabsnet.com)
  • This installment of "Column Watch" is intended to cover chromatography columns and accessories commercially released after Pittcon 2017 through this year's conference held in Orlando, Florida. (chromatographyonline.com)
  • The present discussion is organized around several classes of liquid chromatography (LC) columns. (chromatographyonline.com)
  • The publication presents techniques employing various methods of measurement, such as ion chromatography, atomic absorption, specific ion electrode, ion exchange columns, electrical conductivity, a gravimetric method, differential pulse polarography and others. (environmental-expert.com)
  • Its gas-like diffusivity and liquid-like density in the supercritical phase allow replacing conventional, often noxious, solvents with supercritical CO2. (scribd.com)
  • Supercritical fluids are neither gas nor liquid, but can be compressed gradually from low to high density and they are therefore interesting and important as tunable solvents and reaction media in the chemical process industry. (booktopia.com.au)
  • Separation and processing using supercritical solvents such as CO2 are currently on-line commercially in the food, essential oils and polymer industries. (booktopia.com.au)
  • The "Alternative Solvents" technology platform promotes the use of more sustainable solvents - supercritical / liquid CO 2 , bio-based solvents and solvents made from waste - as replacements for conventional organic solvents. (york.ac.uk)
  • The "Alternative Solvents" technology platform also operates a state of the art semi-preparative supercritical chromatography system. (york.ac.uk)
  • The objective of this study is to assess the potential benefits of using supercritical fluids as solvents in organic synthesis. (epa.gov)
  • Basic principles for the separation of compounds from mixtures using supercritical fluid chromatography (SFC) are similar to the fundamentals of preparative liquid chromatography. (waters.com)
  • Basic principles for isolating compounds with SFC are similar to the fundamental rules for large-scale preparative liquid chromatography. (waters.com)
  • 1. Introduction Supercritical fluid extraction (SFE) of metal species and organometallic compounds has been the subject of many reports in recent years. (scribd.com)
  • Quantification of the extracted metal chelates and organometallic compounds can be achieved by supercritical fluid chromatography (SFC). (scribd.com)
  • Basado en los resultados del estudio se concluye que el método de extracción con fluido supercrítico minimizó los daños ambientales, tiempo, y el trabajo de laboratorio Resumen en inglés A rapid and reliable method for the determination of 25 compounds selected from four classes of pesticides in samples of fresh apples, grapes, pears, and strawberries purchased at a local supermarket, is presented. (worldwidescience.org)
  • Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. (ebooksdownloads.xyz)
  • A system for measuring the solubility of various solid organic compounds in supercritical fluids such as methane or carbon dioxide for example, and for studying the equilibrium between the solid phase and the supercritical phase in a wide pressure and temperature range is disclosed. (freepatentsonline.com)
  • The extraction with supercritical fluid was not efficient to obtain extracts with the highest contents of antioxidants compounds, when compared with the ethanolic extracts. (nih.gov)
  • Despite the large number of studies on the behavior of organic compounds in supercritical fluids, there is little information about its use in the extraction of metals from aqueous media. (scielo.br)
  • 1985. Automatic system for rapid analysis of volatile compounds by purge-and-cold trapping/capillary gas chromatography. (cdc.gov)
  • Chromatography is a family of laboratory techniques for separating mixtures of chemicals into their individual compounds. (encyclopedia.com)
  • The basic principle of chromatography is that different compounds will stick to a solid surface or dissolve in a film of liquid to different degrees. (encyclopedia.com)
  • Because it usually does not alter the molecular structure of the compounds, chromatography can provide a non-destructive way to obtain pure chemicals from various sources. (encyclopedia.com)
  • François I, Dos Santos Pereira A, Sandra P. Comprehensive and off-line supercritical fluid chromatography: reversed phase liquid chromatography for the analysis of complex triglyceride profiles. (ugent.be)
  • In practice, when the fraction of cosolvent is high, the mobile phase is not truly supercritical, but this terminology is used regardless. (wikipedia.org)
  • The mobile phase is composed primarily of supercritical carbon dioxide, but since CO2 on its own is too non-polar to effectively elute many analytes, cosolvents are added to modify the mobile phase polarity. (wikipedia.org)
  • Low viscosity carbon dioxide, the main component of the mobile phase in SFC, enables the use of higher flow rates than those generally used in liquid chromatography. (waters.com)
  • Carbon dioxide at 400 atmospheres is a typical supercritical-fluid mobile phase. (britannica.com)
  • Supercritical fluids show low viscosities and higher diffusivities when used as a mobile phase. (intlabsnet.com)
  • Supercritical Fluid Chromatography (SFC)/Mass Spectrometry (MS) is the ideal tool for lipid profiling due to the features of the mobile phase. (elsevier.com)
  • An organic modifier (most commonly methanol) is often used to extend the solvating power of the mobile phase towards chromatography of more polar analytes. (ucalgary.ca)
  • The supercritical fluid used for the mobile phase of SFC normally has low viscosity and high diffusibility, and is thus advantageous from the standpoint of not harming the separability of samples even under conditions of high flow velocity and allowing a high level of separation and analysis. (justia.com)
  • C18 column (10 mm×250 mm,5 μm) was adopted, with supercritical fluid dioxide as the mobile phase,the ratio of methanol was 0.13%,the flow rate was 12 mL·min-1,column pressure was 13 MPa,column temperature was 318℃, and detection wavelength was 225 nm. (bvsalud.org)
  • Standard column chromatography consists of a solid stationary phase and a liquid mobile phase, while gas chromatography (GC) uses a solid or liquid stationary phase on a solid support and a gaseous mobile phase. (wikipedia.org)
  • SFC combines the high diffusion coefficients of gas chromatography (GC) with the solubility properties of liquid chromatography (LC). (scribd.com)
  • The complexation with appropriate ligands seems a good solution, as the complexed metal ion have an increased solubility in supercritical CO 2 . (scielo.br)
  • The solubility of chloramphenicol in pure supercritical fluid carbon dioxide (SF-CO2) has been determined using a continuously stirred supercritical solubility vessel (SSV) directly interfaced with online supercritical fluid chromatography (SFC) using a single valve interface. (x-mol.com)
  • This system runs extractions, reactions and analysis all in the supercritical phase. (york.ac.uk)
  • Resumen en inglés A bibliographic review on the raceme of propanolol chlorhydrate and its esters was made aimed at compiling the latest methods for its detection and the resolution of its racemic mix in order to provide information to pharmacists, synthesizer chemistry and other professionals connected with this topic. (worldwidescience.org)
  • The spectrofluorometry, the colorimetry, the thinlayer chromatography, and the high oressure liquid chromatography are reported as analysis techniques used for its detection. (worldwidescience.org)
  • Separation of coenzyme Q 10 in CPO and palm fibre oil was carried out using supercritical fluid chromatography with ultra violet detection. (thescipub.com)
  • Different methods such as thin layer chromatography and high performance liquid chromatography coupled with ultraviolet, refractive index, flame ionization detector, and mass spectrometry (MS) detection have long been used in the study of phospholipids. (vt.edu)
  • CO2 cylinders used for SFC are filled with supercritical carbon dioxide generated by industrial plants, meaning that no new carbon dioxide is generated for operating SFC. (technologynetworks.com)
  • Supercritical Fluid Chromatography (SFC) remains the preferred choice for preparative enantioseparation within Drug Discovery Research, where semi-preparative SFC is routinely employed to purify intermediates and final products in quantities up to 50 g. (chromatographytoday.com)
  • Complementary ultra-high-performance liquid chromatography method was developed using Ascentis Express F5 core-shell stationary phase and isocratic elution with 75% acetonitrile/methanol (1:1) and 25% water. (springer.com)
  • The second goal for this work was fractionation of phospholipids from lecithin (a by-product from soybean) by using supercritical fluid extraction (SFE) with methanol-modified CO2. (vt.edu)
  • The column packing material for supercritical fluid chromatography includes polymer particles containing cross-linked polymer, the degree of swelling of which after absorbing tetrahydrofuran and the degree of swelling of which after absorbing methanol are both 1.4 or less. (justia.com)
  • The effects of organic modifier and temperature on the enantioseparation of 10 triazoles and eight imidazoles, using supercritical fluid chromatography with the Chiralpak AD column, have been investigated in this work. (semanticscholar.org)
  • Supercritical fluid chromatography for the enantioseparation of pharmaceuticals. (semanticscholar.org)
  • Comparison of liquid chromatography and supercritical fluid chromatography coupled to compact single quadrupole mass spectrometer for targeted in vitro metabolism assay. (sigmaaldrich.com)
  • Designed with the same enabling technology platform as Waters ACQUITY Ultra-Performance Liquid Chromatography (UPLC) System, PATROL UPLC moves existing liquid chromatography (LC) analysis from off-line Quality Control (QC) laboratories directly to the manufacturing stream resulting in significant improvements in production efficiency with real-time analysis, reducing both process cycle times and assuring product quality. (pharmamanufacturing.com)
  • International Journal of Analytical Mass Spectrometry and Chromatography , 2 , 15-24. (scirp.org)
  • ME Conferences is excited to announce the "10th International Conference on Mass Spectrometry and Chromatography" that will be held in October 08-09, 2018 at Dubai, UAE. (bioindustry.org)
  • This conference provides a perfect symposium for scientists, engineers, directors of companies and students in the field of mass spectrometry and chromatography to meet and share their knowledge. (bioindustry.org)
  • One approach of SFE of metals is by converting charged metal ions into neutral metal chelates using organic chelating agents dissolved in supercritical CO 2 [1-4]. (scribd.com)
  • Effects of organic modifier and temperature on the enantiomeric separation of several azole drugs using supercritical fluid chromatography and the Chiralpak AD column. (semanticscholar.org)
  • article{Toribio2014EffectsOO, title={Effects of organic modifier and temperature on the enantiomeric separation of several azole drugs using supercritical fluid chromatography and the Chiralpak AD column. (semanticscholar.org)
  • 1988. Standard method for measuring volatile organic matter by aqueous-injection gas chromatography - method D 2908-87. (cdc.gov)
  • Our objective in this project is to determine the feasibility of carrying out organic synthesis reactions in supercritical fluids. (epa.gov)
  • Our objective is to answer the fundamental question 'is it feasible and perhaps even more advantageous to carry organic synthesis reactions in supercritical fluids? (epa.gov)
  • The study describes two different methods of extraction: solid-liquid extraction with acetone and supercritical fluid extraction. (worldwidescience.org)
  • Table 7-1 lists the applicable analytical methods for determining diazinon and its metabolites in biological fluids and tissues. (cdc.gov)
  • Chapters cover key methods for sample introductions to the ion source, including direct flow, gas chromatography, liquid chromatography, and capillary electrophoresis. (springer.com)
  • We are proposing to use three different reactions as model reactions, (1) non catalytic Diels-Alder reaction to assess the fundamentals or reactions in supercritical fluids, (2) an asymmetric synthesis to assess the value of the approach in enantioselective pharmaceuticals synthesis and (3) metathesis reaction to demonstrate selectivity in specialty chemicals synthesis. (epa.gov)
  • Insights into chiral recognition mechanisms in supercritical fluid chromatography. (semanticscholar.org)
  • Under this condition,the SFC separation process was normal-phase chromatography . (bvsalud.org)
  • In this episode we will talk about the workflow of chiral analysis, applications areas within the pharmaceutical industry, and advantages of using SFC as it relates to analytical and preparative chromatography. (chromatographyonline.com)
  • The use of supercritical fluids in analytical chemistry is still grow- ing. (springer.com)
  • Analytical Chemistry Chromatographie Chromatography Extraction Extraktion (Chem. (springer.com)
  • Although supercritical fluid chromatography (SFC) is not a new technique, preparative SFC is becoming increasingly more popular with advances in instrumentation, software and chemistry. (waters.com)
  • Chromatography technique developed substantially as a result of the work of Archer John Porter Martin and Richard Laurence Millington Synge during the 1940s and 1950s, for which they won the 1952 Nobel Prize in Chemistry . (wikipedia.org)
  • This book discusses the recent developments which will lead to the routine use of supercritical fluid in analytical extensive chemistry. (booktopia.com.au)
  • Lee, CH & Holder, GD 1995, ' Use of Supercritical Fluid Chromatography for Obtaining Mass Transfer Coefficients in Fluid-Solid Systems at Supercritical Conditions ', Industrial and Engineering Chemistry Research , vol. 34, no. 3, pp. 906-914. (elsevier.com)
  • Osanai, Y , Toshima, K & Matsumura, S 2001, ' Lipase-catalyzed ring-opening polymerization of β-butyrolactone: End-group analysis of poly(3-hydroxybutanoate) using supercritical fluid chromatography ', Macromolecular Chemistry and Physics , vol. 202, no. 11, pp. 171-177. (elsevier.com)
  • The Supercritical Fluid Chromatography (Sfc) market analysis is provided for the United States markets including development trends, competitive landscape analysis, and key regions development status. (mynewsdesk.com)
  • The European Supercritical fluid chromatography reagents report defines and segments the concerned market in Europe with analysis and forecast of revenue. (prweb.com)
  • Browse through the TOC of the European supercritical fluid chromatography reagents market report, to get an idea of the in-depth analysis provided. (prweb.com)
  • Confirmatory analysis was carried out by gas chromatography with mass spectrometry in the selected-ion monitoring (SIM) mode. (worldwidescience.org)
  • SFC is not accepted by Pharmacopeia committees for the analysis of drugs and medical forms to the same extent as Gas Chromatography, High-Performance Liquid Chromatography or even Thin Layer Chromatography. (scirp.org)
  • This separation took 12 min that is the shortest liquid chromatography run in analysis of all tocopherol derivatives reported so far. (springer.com)
  • One technique that has made steady advances in pharmaceutical analysis is supercritical fluid chromatography (SFC). (ebooksdownloads.xyz)
  • PerkinElmer Life and Analytical Sciences, a global leader in application-focused measurement and analysis solutions, today at PITTCON® 2008, Booth #2555, announced the introduction of the Series 225 LC Autosampler to enable customers to meet the demanding needs for automation, quantitation and throughput in analyses using liquid chromatography (LC). (environmental-expert.com)
  • A column packing material for supercritical fluid chromatography which allows good peak shape to be obtained in the analysis of free fatty acids, etc. and in the analysis of agricultural chemicals, etc., and has excellent durability for repeated analysis. (justia.com)
  • Two well-known phytochemical inhibitors, yohimbine and resveratrol, were investigated, and reliable conclusions were drawn from these experiments with both UHPLC-MS and UHPSFC-MS. At the end, the proposed strategy of optimized chromatography combined with simple MS device has been shown to potentially compete with the widely used combination of generic chromatography and highly selective MS/MS device for simple in vitro CYP inhibition assays. (sigmaaldrich.com)
  • Countercurrent chromatography (CCC, also counter-current chromatography) is a form of liquid-liquid chromatography that uses a liquid stationary phase that is held in place by inertia of the molecules composing the stationary phase accelerating toward the center of a centrifuge due to centripetal force and is used to separate, identify, and quantify the chemical components of a mixture. (wikipedia.org)
  • Hydrodynamic instruments are often marketed as high-speed or high-performance countercurrent chromatography (HSCCC and HPCCC respectively) instruments which rely on the Archimedes' screw force in a helical coil to retain the stationary phase in the column. (wikipedia.org)
  • The predecessor of modern countercurrent chromatography theory and practice was countercurrent distribution (CCD). (wikipedia.org)
  • In countercurrent chromatography centripetal or gravitational forces immobilize the stationary liquid layer. (wikipedia.org)
  • Nearly any pair of immiscible solutions can be used in countercurrent chromatography provided that the stationary phase can be successfully retained. (wikipedia.org)
  • The CO2 subsequently becomes supercritical post the injector and in the column oven when the temperature and pressure it is subjected to are raised above the critical point of the liquid and the supercritical state is achieved. (wikipedia.org)
  • The advantages of supercritical CO , such as having dif- 2 fusivity like a gas and solvating power depending on temperature and pressure, are also valid for other fluids and modified fluids. (springer.com)
  • Supercritical Fluid Chromatography (SFC) is a hybrid of gas and liquid chromatography that combines some of the best features of both Supercritical Fluid exist at temperatures and pressures above its critical temperature and pressure and have densities, viscosities and other properties that are intermediates between those of the substance in its gaseous and liquid state. (coursehero.com)
  • the fluid delivery device comprises a pump which pumps the supercritical fluid and an associated pressure regulator which regulates pressure of the supercritical fluid pumped by the pump and temperature regulator which regulates temperature of the pumped fluid. (freepatentsonline.com)
  • the fluid delivery device comprises a filter, a device which establishes a leak rate and a gas surge capacity and the pump is associated with a constant-temperature bath. (freepatentsonline.com)
  • In gas-liquid chromatography (now called gas chromatography), the material that separates components is chemically bonded to the solid support, which improves the temperature stability of the column's packing. (encyclopedia.com)
  • This also provides a glimpse of the segmentation of the supercritical fluid chromatography reagents market in the same region, and is supported by various tables and figures. (prweb.com)
  • Globally, Europe is the second-largest market for supercritical fluid chromatography reagents. (prweb.com)
  • The demand for the supercritical fluid chromatography reagents is anticipated to increase due to the investments made by chromatography companies and the mergers & acquisitions between several firms operational in this sector. (prweb.com)
  • Furthermore, production facility expansion by various chromatography companies, to cater to the growing need of chromatography users, is another factor which is likely to drive the European supercritical fluid chromatography reagents market during the forecast period. (prweb.com)
  • Germany held the largest share in the European supercritical fluid chromatography reagents market, of around 23.1% in 2013, followed by France with a share of around 21.9% in the same year. (prweb.com)
  • This market is segmented and forecast based on products and processes of supercritical fluid chromatography reagents in Europe. (prweb.com)
  • In addition, it presents a competitive landscape and company profiles of the key players in the market, including major companies which provide supercritical fluid chromatography reagents as a product. (prweb.com)
  • Planar chromatography (K. Ferenczi-Fodor, Z. Végh). (elsevier.com)
  • A somewhat different approach is the set of techniques known as "planar" or "thin layer" chromatography (TLC), in which no column is used at all. (encyclopedia.com)
  • High-pressure vessels are expensive and bulky, and special materials are often needed to avoid dissolving gaskets and O-rings in the supercritical fluid. (wikipedia.org)
  • The present method allowed for fast and high-resolution separation of monoesters to tetra-esters within a shorter time (15 min) as compared to the conventional high-performance liquid chromatography. (go.jp)
  • A high-throughput, rapid, sensitive, environmentally friendly, and economical supercritical fluid chromatography with triple quadruple mass spectrometry method was established and validated for the first time to determine a cerebral stroke treatment drug named 3-n-butylphthalide in dog plasma. (curehunter.com)
  • paper chromatography , gas chromatography , and what would become known as high-performance liquid chromatography . (wikipedia.org)
  • Supercritical fluid extraction-high performance liquid chromatography: on-line and off-line strategies. (booktopia.com.au)
  • Furthermore, carbon dioxide, which is usually used as the supercritical fluid, attains a supercritical state (supercritical carbon dioxide) under relatively mild conditions, and has high dissolving capability for a broad range of components, and so does not tend to impose restrictions as to the measured components. (justia.com)
  • The components of a CCC system are similar to most liquid chromatography configurations, such as high-performance liquid chromatography. (wikipedia.org)
  • Thar Technologies, Inc., the only company worldwide providing supercritical fluid chromatography (SFC) systems spanning from analytical to preparative to process scale, announced today that it has entered into an agreement to develop SFC applications with the Norwegian University of Life Sciences (NULS). (chromatographyonline.com)
  • Thar Technologies, Inc., provider of supercritical fluid chromatography (SFC) systems spanning from analytical to preparative to process scale, announced that it opened the European headquarters of its SFC division in Berlin. (chemeurope.com)