A CHROMATOGRAPHY method using supercritical fluid, usually carbon dioxide under very high pressure (around 73 atmospheres or 1070 psi at room temperature) as the mobile phase. Other solvents are sometimes added as modifiers. This is used both for analytical (SFC) and extraction (SFE) purposes.
The branch of chemistry dealing with detection (qualitative) and determination (quantitative) of substances. (Grant & Hackh's Chemical Dictionary, 5th ed)
Methodologies used for the isolation, identification, detection, and quantitation of chemical substances.
A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)
A plant genus of the family LAMIACEAE that is closely related to the European pennyroyal (MENTHA PULEGIUM).
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)
The management of all procurement, distribution, and storage of equipment and supplies, as well as logistics management including laundry, processing of reusables, etc.
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
Authoritative treatises on drugs and preparations, their description, formulation, analytic composition, physical constants, main chemical properties used in identification, standards for strength, purity, and dosage, chemical tests for determining identity and purity, etc. They are usually published under governmental jurisdiction (e.g., USP, the United States Pharmacopoeia; BP, British Pharmacopoeia; P. Helv., the Swiss Pharmacopoeia). They differ from FORMULARIES in that they are far more complete: formularies tend to be mere listings of formulas and prescriptions.
That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.
Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)
A lipid-soluble benzoquinone which is involved in ELECTRON TRANSPORT in mitochondrial preparations. The compound occurs in the majority of aerobic organisms, from bacteria to higher plants and animals.
Oils derived from plants or plant products.
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
Small molecules that are required for the catalytic function of ENZYMES. Many VITAMINS are coenzymes.
The palm family of order Arecales, subclass Arecidae, class Liliopsida.
A republic in southern Africa, between NAMIBIA and ZAMBIA. It was formerly called Bechuanaland. Its capital is Gaborone. The Kalahari Desert is in the west and southwest.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.
A republic in southern Africa, south of ANGOLA and west of BOTSWANA. Its capital is Windhoek.
Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.
An agricultural fungicide and seed treatment agent.
Chromatographic techniques in which the mobile phase is a liquid.
Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.

Field-based supercritical fluid extraction of hydrocarbons at industrially contaminated sites. (1/62)

Examination of organic pollutants in groundwaters should also consider the source of the pollution, which is often a solid matrix such as soil, landfill waste, or sediment. This premise should be viewed alongside the growing trend towards field-based characterisation of contaminated sites for reasons of speed and cost. Field-based methods for the extraction of organic compounds from solid samples are generally cumbersome, time consuming, or inefficient. This paper describes the development of a field-based supercritical fluid extraction (SFE) system for the recovery of organic contaminants (benzene, toluene, ethylbenzene, and xylene and polynuclear aromatic hydrocarbons) from soils. A simple, compact, and robust SFE system has been constructed and was found to offer the same extraction efficiency as a well-established laboratory SFE system. Extraction optimisation was statistically evaluated using a factorial analysis procedure. Under optimised conditions, the device yielded recovery efficiencies of >70% with RSD values of 4% against the standard EPA Soxhlet method, compared with a mean recovery efficiency of 48% for a commercially available field-extraction kit. The device will next be evaluated with real samples prior to field deployment.  (+info)

Simultaneous measurement of fluoroquinolones in eggs by a combination of supercritical fluid extraction and high pressure liquid chromatography. (2/62)

Simultaneous detection of the fluoroquinolone antibiotics ciprofloxacin, enrofloxacin, ofloxacin, and norfloxacin in eggs by a combination of supercritical fluid extraction (SFE) and high pressure liquid chromatography (HPLC) was studied. Lipid matrices that have been considered to result in poor extraction and isolation of fluoroquinolones in eggs were removed first by SFE with supercritical CO(2) alone, and then the fluoroquinolones were extracted by SFE with supercritical CO(2) containing 20% (v/v) methanol for HPLC analysis. A time-course study of the extraction of lipid matrices of eggs suggested that the SFE method successfully removed the matrices within 20 min. When the fluoroquinolones added to control eggs were extracted by SFE, the extraction efficiency was similar to that by the solvent extraction method, giving the recovery percentages from 83 to 96% in a 40 min-extraction time. The fluoroquinolones extracted from eggs by SFE were analyzed simultaneously by HPLC equipped with a fluorescence detector with detection sensitivity at about 10 ppb for the detection limit. The standard calibration profiles of fluoroquinolones showed linear responses to HPLC, showing more than 0.995 for the mean r(2) value. This is the first report of the simultaneous measurement of fluoroquinolones in eggs by a combination of SFE and HPLC. Using the SFE method allowed us to avoid extensive sample preparation such as solvent extraction and chromatographic cleanup that are basically required in extraction of fluoroquinolones.  (+info)

Pesticide residues in canned foods, fruits, and vegetables: the application of Supercritical Fluid Extraction and chromatographic techniques in the analysis. (3/62)

Multiple pesticide residues have been observed in some samples of canned foods, frozen vegetables, and fruit jam, which put the health of the consumers at risk of adverse effects. It is quite apparent that such a state of affairs calls for the need of more accurate, cost-effective, and rapid analytical techniques capable of detecting the minimum concentrations of the multiple pesticide residues. The aims of this paper were first, to determine the effectiveness of the use of Supercritical Fluid Extraction (SFE) and Supercritical Fluid Chromatography (SFC) techniques in the analysis of the levels of pesticide residues in canned foods, vegetables, and fruits; and second, to contribute to the promotion of consumer safety by excluding pesticide residue contamination from markets. Fifteen different types of imported canned and frozen fruits and vegetables samples obtained from the Houston local food markets were investigated. The major types of pesticides tested were pyrethroids, herbicides, fungicides, and carbamates. By using these techniques, the overall data showed 60.82% of the food samples had no detection of any pesticide residues under this investigation. On the other hand, 39.15% different food samples were contaminated by four different pyrethroid residues +/- RSD% ranging from 0.03 +/- 0.005 to 0.05 +/- 0.03 ppm, of which most of the pyrethroid residues were detected in frozen vegetables and strawberry jam. Herbicide residues in test samples ranged from 0.03 +/- 0.005 to 0.8 +/- 0.01 ppm. Five different fungicides, ranging from 0.05 +/- 0.02 to 0.8 +/- 0.1 ppm, were found in five different frozen vegetable samples. Carbamate residues were not detected in 60% of investigated food samples. It was concluded that SFE and SFC techniques were accurate, reliable, less time consuming, and cost effective in the analysis of imported canned foods, fruits, and vegetables and are recommended for the monitoring of pesticide contaminations.  (+info)

Supercritical fluid clean-up of environmental samples for the analysis of polycyclic aromatic hydrocarbons using time-of-flight secondary ion mass spectrometry. (4/62)

A novel sample-pretreatment method for time-of-flight secondary ion mass spectrometry (TOF-SIMS) was developed using supercritical fluid extraction (SFE). In SFE, the extraction efficiency of a certain organic matter is controlled by the pressure and temperature of supercritical CO2. Two-step SFE (1st step at 10 Mpa, 40 degrees C; 2nd step at 30 MPa, 120 degrees C) was applied to diesel exhaust particles containing many kinds of n-alkanes and aromatic species. n-Alkanes and polycyclic aromatic hydrocarbons (PAHs) were extracted in the 1st and 2nd steps, respectively. This selectivity was utilized for the sample preparation of TOF-SIMS analysis. Diesel exhaust particles after the 1st step of extraction were analyzed with TOF-SIMS, aiming at PAHs as analytical targets. The obtained spectrum was simplified, and mass peaks of individual PAHs were easily assigned, because unwanted compounds, like n-alkanes, were selectively removed by SFE. Furthermore, a simple calculation elucidated the outline of the spectrum.  (+info)

Impacts of extraction methods in the rapid determination of atrazine residues in foods using supercritical fluid chromatography and enzyme-linked immunosorbent assay: microwave solvent vs. supercritical fluid extractions. (5/62)

It is an accepted fact that many food products that we eat today have the possibility of being contaminated by various chemicals used from planting to processing. These chemicals have been shown to cause illnesses for which some concerned government agencies have instituted regulatory mechanisms to minimize the risks and the effects on humans. It is for these concerns that reliable and accurate rapid determination techniques are needed to effect proper regulatory standards for the protection of people's nutritional health. This paper, therefore, reports the comparative evaluation of the extraction methods in the determination of atrazine (commonly used in agricultural as a herbicide) residues in foods using supercritical fluid chromatography (SFC) and enzyme-linked immunosorbent assay (ELISA) techniques. Supercritical fluid extraction (SFE) and microwave solvent extraction (MSE) methods were used to test samples of frozen vegetables, fruit juice, and jam from local food markets in Houston. Results showed a high recovery percentage of atrazine residues using supercritical fluid coupled with ELISA and SFC than with MSE. Comparatively, however, atrazine was detected 90.9 and 54.5% using SFC and ELISA techniques, respectively. ELISA technique was, however, less time consuming, lower in cost, and more sensitive with low detection limit of atrazine residues than SFC technique.  (+info)

Stabilized nanoparticles of phytosterol by rapid expansion from supercritical solution into aqueous solution. (6/62)

The basic objective of this work was to form stable suspensions of submicron particles of phytosterol, a water-insoluble drug, by rapid expansion of supercritical solution into aqueous solution (RESSAS). A supercritical phytosterol/CO2 mixture was expanded into an aqueous surfactant solution. In these experiments 4 different surfactants were used to impede growth and agglomeration of the submicron particles resulting from collisions in the free jet. The concentration of the drug in the aqueous surfactant solution was determined by high-performance liquid chromatography, while the size of the stabilized particles was measured by dynamic light scattering. Submicron phytosterol particles (<500 nm) were stabilized and in most cases a bimodal particle size distribution was obtained. Depending on surfactant and concentration of the surfactant solution, suspensions with drug concentrations up to 17 g/dm3 could be achieved, which is 2 orders of magnitude higher than the equilibrium solubility of phytosterol. Long-term stability studies indicate modest particle growth over 12 months. Thus, the results demonstrate that RESSAS can be a promising process for stabilizing submicron particles in aqueous solutions.  (+info)

Isolation of palm tocols using supercritical fluid chromatography. (7/62)

Crude palm oil contains 600 to 1000 ppm of tocols in the form of tocopherols and tocotrienols. These palm tocols have been isolated and analyzed in the past by various chromatographic techniques such as open column chromatography, high-performance liquid chromatography, as well as thin-layer chromatography. Supercritical fluid chromatography (SFC) has emerged as a more advanced chromatographic technique in recent years. The tocols present in palm oil are successfully isolated using SFC. Identification of these tocols is supported by various spectroscopic techniques such as 1H NMR, 13C NMR, and mass spectrometry.  (+info)

Feasibility study of online supercritical fluid extraction-liquid chromatography-UV absorbance-mass spectrometry for the determination of proanthocyanidins in grape seeds. (8/62)

Online coupling of supercritical fluid extraction (SFE) with liquid chromatography (LC)-UV absorbance-electrospray ionization (ESI)-mass spectrometry (MS) is evaluated for the determination of proanthocyanidins in grape seeds. The solid-phase intermediate trap is optimized in order to enhance the collection efficiency for the extracted polar components. Pure supercritical CO2 is used first to remove the oil in the seeds. Then methanol-modified CO2 is used to remove the polar components (e.g., phenolic compounds). Catechin and epicatechin (90%) are extracted out of the de-oiled after 240 min with 40% methanol as a modifier. Both singly-linked (B-type) and doubly-linked (A-type) procyanidins are identified by LC-ESI-MS, as well as their galloylated derivatives. The hyphenated system combines the extraction, separation, and detection in series. The experimental design minimizes the chance of analyte oxidation, degradation, and contamination. The traditional off-line SFE-LC method is also studied for comparison with the online method. Both advantages and disadvantages are observed for the online mode.  (+info)

33. A. Rajendran, T. Gilkison, M. Mazzotti. Pressure drop effects in supercritical fluid chromatography, 1st International Conference on Supercritical Fluid Chromatography, Pittsburgh USA, Sept 2007 34. W. Chen, A. Rajendran. Optimization of binary separations in supercritical fluid chromatography, 1st International Conference on Supercritical Fluid Chromatography, Pittsburgh USA, Sept 2007 35. W. Chen, M. Aman Ullah, A. Rajendran. Chiral separation of flurbiprofen by supercritical fluid chro- matography, 1st International Conference on Supercritical Fluid Chromatography, Pittsburgh USA, Sept2007 36. A. Rajendran, S. Farooq, V. Kariwala. Blank correction in dynamic column breakthrough experiments, 9th International Conference on Fundamentals Of Adsorption, Sicily Italy, May 2007 37. A. Rajendran, T. Gilkison, M. Mazzotti. Pressure drop effects in supercritical fluid chromatography, 9th International Conference on Fundamentals Of Adsorption, Sicily Italy, May 2007 38. W. Chen, A. Rajendran. ...
[98 Pages Report] Check for Discount on United States Supercritical Fluid Chromatography (Sfc) Market Report 2017 report by QYResearch Group. In this report, the United States Supercritical Fluid Chromatography (Sfc)...
TY - JOUR. T1 - Supercritical fluid chromatography reduction of hydrogen/deuterium back exchange in solution-phase hydrogen/deuterium exchange with mass spectrometric analysis. AU - Emmett, Mark. AU - Kazazic, Sasa. AU - Marshall, Alan G.. AU - Chen, Wei. AU - Shi, Stone D H. AU - Bolaños, Ben. AU - Greig, Michael J.. PY - 2006/10/1. Y1 - 2006/10/1. N2 - The single biggest problem with solution-phase H/D exchange as a mass spectrometric probe of surface exposure in a protein (or protein complex) is back-exchange of H for D after the initial H/D exchange has been quenched. Back-exchange results in loss of pertinent data and also greatly hampers data analysis. Previously, very fast, cold (0-4 °C) HPLC was performed to help reduce back-exchange, but calculated back-exchange still averages ∼30%. In this report, supercritical fluid chromatography replaces HPLC as the desalting/separation technique prior to mass analysis, providing a dramatic reduction in back-exchange compared to the fast, cold ...
Palm oil is known to host a variety of phytonutrients; some having antioxidant property such as the carotenes and vitamin E. These antioxidants are also present in the oil recovered from the palm-pressed fibre. Study was carried out to investigate the presence of coenzyme Q10, yet another non-glyceride compound which possesses antioxidant property in crude palm oil (CPO) and palm fibre oil. Separation of coenzyme Q10 in CPO and palm fibre oil was carried out using supercritical fluid chromatography with ultra violet detection. 1H and 13C NMR were used for its characterisation. Calibration with authentic standard shows that there are 10-80 ppm coenzyme Q10 in CPO while its concentration in palm fibre oil is 1000-1500 ppm.
While supercritical fluid chromatography (SFC) has been available for decades, very few labs have chosen to take advantage of its remarkable chromatographic properties. The separation of isomeric compounds that are usually challenging for high.performance liquid chromatography (HPLC) can be accomplished by SFC. Coupling the exceptional chromatographic properties of SFC with the sensitivity of mass spectrometric detection results in a powerful piece of equipment that very few laboratories have utilized. Glycosphingolipids (GSLs) are characteristic components of eukaryotic cells, found in the carbohydrate-rich cell membrane. They represent hundreds of diverse chemical structures composed of different carbohydrate and ceramide moieties. The simplest hexosylceramides (HexCer), which are neutral GSLs, are represented by glucosylceramide (GluCer) and galactosylceramide (GalCer). GluCer and GalCer undergo their own distinctive metabolic pathways that effect different biological responses. GSL ...
Preparative Supercritical Fluid Chromatography (pSFC). As an environment-friendly approach to purification applications, pSFC is being used routinely for an increasing number of applications.. During the recent years SFC has gained acceptance in drug discovery for high-throughput purification of enantiomers. Hence, pSFC replaces preparative HPLC (pHPLC) as major technology for chiral separations in many pharmaceutical companies. Preparative SFC excels not only at separating and purifying chiral compounds but is also powerful for achiral separations and can be implemented in most steps of drug discovery. It may offer potential advantages over pHPLC for purity upgrading of active pharmaceutical ingredients or drug intermediates, impurity isolation and non-aqueous purification.. The use of pSFC as an alternative option to pHPLC receives also a growing interest for natural products, environmental (pesticides) and petroleum (biofuels) applications. ...
Preparative Supercritical Fluid Chromatography (pSFC). As an environment-friendly approach to purification applications, pSFC is being used routinely for an increasing number of applications.. During the recent years SFC has gained acceptance in drug discovery for high-throughput purification of enantiomers. Hence, pSFC replaces preparative HPLC (pHPLC) as major technology for chiral separations in many pharmaceutical companies. Preparative SFC excels not only at separating and purifying chiral compounds but is also powerful for achiral separations and can be implemented in most steps of drug discovery. It may offer potential advantages over pHPLC for purity upgrading of active pharmaceutical ingredients or drug intermediates, impurity isolation and non-aqueous purification.. The use of pSFC as an alternative option to pHPLC receives also a growing interest for natural products, environmental (pesticides) and petroleum (biofuels) applications. ...
The effect of pressure drop on the performance of supercritical fluid chromatography systems using a modified mobile phase (carbon dioxide + ethanol) was studied. Experiments were performed on a Lichrospher-RP-18 column with phenanthrene as a solute. A wide range of back pressures (130 to 210 bar) and modifier concentrations (2 to 7% w/w) have been explored. Experiments yielding both small and large pressure drops were performed. From these experiments, parameters to describe pressure drop, retention, and column efficiency were extracted, and were used to simulate the dynamics of the chromatographic column. A good match between the experimentally measured and calculated values of pressure drop, retention times, and column efficiency was observed. At low back pressure and modifier composition, significant loss of column efficiency was observed.
François, I., Dos Santos Pereira, A., & Sandra, P. (2009). Comprehensive and off-line supercritical fluid chromatography: reversed phase liquid chromatography for the analysis of complex triglyceride profiles. High Performance Liquid Phase Separations and Related Techniques, 34th International symposium, Abstracts. Presented at the 34th International symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2009 ...
WORCESTER, Mass., July 12, 2013 /PRNewswire/ -- Averica Discovery Announces Winner of First Averica Award for Supercritical Fluid Chromatography (SFC). -...
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(PRWEB) September 10, 2014 -- The European Supercritical fluid chromatography reagents report defines and segments the concerned market in Europe with analysis
Mass spectrometry (MS) is a technique widely implemented for the measurement of environmental pollutants. A critical tool for the analysis of persistent organic pollutants (POPs) over several decades, MS as coupled with liquid and gas chromatography (LC and GC) techniques enables the analysis of emerging POPs. The aim of this thesis was to investigate the use of alternative MS-based techniques to assist specific analytical challenges including separation of stereoisomers using supercritical fluid chromatography (SFC), reduced ionization competition with appropriate mobile phase additives, and applied rotationally averaged collision-cross section (CCS) of ions via ion mobility measurements of emerging POPs.. Chromatographic efficiency improvements for the brominated flame retardant, hexabromocyclododecane (HBCDD), were implemented through the development of two supercritical fluid chromatography (SFC) methods. Based on the inherent qualities of supercritical fluids, separation of both predominant ...
Mass spectrometry (MS) is a technique widely implemented for the measurement of environmental pollutants. A critical tool for the analysis of persistent organic pollutants (POPs) over several decades, MS as coupled with liquid and gas chromatography (LC and GC) techniques enables the analysis of emerging POPs. The aim of this thesis was to investigate the use of alternative MS-based techniques to assist specific analytical challenges including separation of stereoisomers using supercritical fluid chromatography (SFC), reduced ionization competition with appropriate mobile phase additives, and applied rotationally averaged collision-cross section (CCS) of ions via ion mobility measurements of emerging POPs.. Chromatographic efficiency improvements for the brominated flame retardant, hexabromocyclododecane (HBCDD), were implemented through the development of two supercritical fluid chromatography (SFC) methods. Based on the inherent qualities of supercritical fluids, separation of both predominant ...
TY - JOUR. T1 - Highly porous organic nanoparticles formed from supercritical carbon dioxide mediated sol-emulsion-gel method. AU - Lee, Jun Young. AU - Kim, Jung Hyun. PY - 2004/5/5. Y1 - 2004/5/5. N2 - Highly porous organic nanoparticles have been prepared by adapting a novel method, sol-emulsion-gel process, through stable dispersion of nanometer-scaled emulsion droplets into continuous phase of supercritical carbon dioxide (ScCO2), sol-gel chemistry in emulsion droplets, and then supercritical drying. This principle offers faithful preparation of nanoparticles (35-90 nm in diameter) having pores of 1-3 nm in radius and high specific surface area (over 2000 m2/g).. AB - Highly porous organic nanoparticles have been prepared by adapting a novel method, sol-emulsion-gel process, through stable dispersion of nanometer-scaled emulsion droplets into continuous phase of supercritical carbon dioxide (ScCO2), sol-gel chemistry in emulsion droplets, and then supercritical drying. This principle offers ...
A specialty phase designed for SFC with a high density Diol surface coverage which ensures separations better and more reproducible than conventional unbonded silica. GreenSep Diol is particularly suitable for acidic and basic analytes.
The Laboratory for the Analysis of Medicines (LAM) has developed a solid expertise in drug analysis and bioanalysis. Its scope of interest has been extended to diagnostic biomarkers and biopharmaceuticals. Research and routine activities take place in a quality environment.
The piquant and peppery flavor of American Blue and Roquefort cheese is largely due to the short and medium chain fatty acids, methyl ketones and secondary alcohols. The free fatty acids contribute flavor themselves and are also precursors of methyl ketones. Lipase action during the cheese ripening leads to formation of free fatty acids (FFA). The short chain FFA (C6 to C10) are more peppery in flavor than long chain FFA. Conventional methods of FFA analysis suffer from limitations such as loss of volatile fatty acids during derivatization of samples and difficulties in extraction and separation of short, medium and long chain fatty acids in a single analysis. Enhanced FFA recoveries from spiked matrix samples were obtained at 680 atm by SFE/SFC procedure with a 5% methanol modifier containing 1% acetic acid. A procedure was developed utilizing supercritical fluid extraction to isolate the FFA and subsequently separate and quantitate the FFA with supercritical fluid chromatography. The ...
Kenaf (|i|Hibiscus cannabinus|/i|) from the family Malvaceae, is a valuable fiber plant native to India and Africa and is currently planted as the fourth commercial crop in Malaysia. Kenaf seed oil contains alpha-linolenic acid, phytosterol such as |i|β|/i|-sitosterol, vitamin E, and other antioxidants with chemopreventive properties. Kenaf seeds oil (KSO) was from supercritical carbon dioxide extraction fluid (SFE) at 9 different permutations of parameters based on range of pressures from 200 to 600 bars and temperature from 40 to 80°C. They were 200/40, 200/60, 200/80, 400/40, 400/60, 400/80, 600/40, 600/60, and 600/80. Extraction from 9 parameters of KSO-SFE was screened for cytotoxicity towards human colorectal cancer cell lines (HT29) and mouse embryonic fibroblast (NIH/3T3) cell lines using MTS assay. KSO-SFE at 600/40 showed the strongest cytotoxicity towards HT29 with IC|sub|50|/sub| of 200 µg/mL. The IC|sub|50|/sub| for NIH/3T3 was not detected even at highest
The solubility of heptanoic acid and octanoic acid in supercritical carbon dioxide has been determined at temperatures of (313.15, 323.15, and 333.15) K over a pressure range of (8.5 to 30.0) MPa, depending upon the solute. The solubility of heptanoic acid ranged from a solute concentration of (0.08 ± 0.03) kg • m -3 (T = 323.15 K, p = 8.5 MPa) to (147 ± 0.2) kg • m -3 (T = 323.15 K, p = 20.0 MPa). The lowest octanoic acid solubility obtained was a solute concentration of (0.40 ± 0.1) kg • m -3 (T = 333.15 K, p = 10.0 MPa), while the highest solute concentration was (151 ± 2) kg • m -3 (T = 333.15 K, p = 26.7 MPa). In addition, solubility experiments were performed for nonanoic acid in supercritical carbon dioxide at 323.15 K and pressures of (10.0 to 30.0) MPa to add to the solubility data previously published by the authors. In general, carboxylic acid solubility increased with increasing solvent density. The results also showed that the solubility of the solutes decreased with ...
TY - JOUR. T1 - Highly Fluorous Complexes of Ruthenium and Osmium and Their Solubility in Supercritical Carbon Dioxide. AU - Berven, Bradley. AU - Koutsantonis, George. AU - Skelton, Brian. AU - Trengove, R.D.. AU - White, Allan. PY - 2009. Y1 - 2009. N2 - A series of ruthenium and osmium complexes containing highly fluorous diphosphine ligands FPPF = (F13C6C6H4-p)2P(CH2)2P(p-C6H4C6F13)2 (dfppe) and (F13C6C6H4-p)2P(CH2)3P(p-C6H4C6F13)2 (dfppp) has been prepared. The fluorous diphosphine ligands incorporate four C6F13 fluoro-ponytails, and these have been effective in solubilizing the complexes in supercritical carbon dioxide (scCO2). Precise solubility measurements in scCO2 were performed for some of the complexes. The new complexes [MX2(FPPF)2] and [MX(FPPF)(η-C5H5)], M = Ru, Os, X = Cl, Br, have been characterized by a number of spectroscopic techniques and their electrochemical properties measured, three of the ruthenium complexes also being characterized by single-crystal X-ray studies. ...
This study discusses utilization of supercritical carbon dioxide for impregnation of cellulose acetate films with thymol in order to produce material with anti-biofilm activity against Pseudomonas aeruginosa and Staphylococcus aureus. Analysis of anti-biofilm activity of cellulose acetate beads impregnated with thymol suggested that optimal thymol loading was in the range from 26% to 30% for efficient reduction of biofilm formation and eradication of pre-formed biofilms. Polymer films were fabricated by the solvent casting method from polymer solutions of different contents, and loaded with thymol using supercritical carbon dioxide at 15.5 MPa and 35 degrees C. The film containing 30% of thymol (F1 30%) exhibited substantial anti-adhesion properties inhibiting biofilm formation on its surface and considerably reduced formation of biofilms on the surrounding surfaces (up to 80%) by all tested strains including antibiotic resistant P. aeruginosa DM50 and methicillin-resistant S. aureus ...
The effects of microwave irradiation (2.45 GHz, 200 W) on glycosylation promoted by a solid super acid in supercritical carbon dioxide was investigated with particular attention paid to the structure of the acceptor substrate. Because of the symmetrical structure and high diffusive property of supercritical carbon dioxide, microwave irradiation did not alter the temperature of the reaction solution, but enhanced reaction yield when aliphatic acceptors are employed. Interestingly, the use of a phenolic acceptor under the same reaction conditions did not show these promoting effects due to microwave irradiation. In the case of aliphatic diol acceptors, the yield seemed to be dependent on the symmetrical properties of the acceptors. The results suggest that microwave irradiation do not affect the reactivity of the donor nor promoter independently. We conclude that the effect of acceptor structure on glycosylation yield is due to electric delocalization of hydroxyl group and dielectrically symmetric
Effect of supercritical carbon dioxide on micro-mechanical properties of electrodesposited goldEffect of supercritical carbon dioxide on micro-mechanical properties of electrodesposited gold ...
In 1822, almost 200 years ago, Baron Charles Cagniard de Latour (1777-1859) discovered the critical phenomena or critical state [1] [2]. At that time, it was described as a curiosity. However, it is now used as an advanced extraction and analytical technology in industry and research. Extraction with supercritical fluids (SFs) was welcome from the very beginning. In the present paper, the application to chromatography of the critical phenomena of compressed gases or overheated liquids as supercritical fluids will be discussed. Supercritical Fluid Chromatography (SFC) received an uneasy welcome, mainly because of the lack of commercially available analytical instruments. Even today, only a small number of industrial companies are manufacturing SFC instrumentation. A very small spectrum of columns is manufactured specially for SFC. SFC is not accepted by Pharmacopeia committees for the analysis of drugs and medical forms to the same extent as Gas Chromatography, High-Performance Liquid Chromatography or
Alibaba.com offers 198 supercritical co2 fluid extraction device products. About 56% of these are other pharmaceutical machinery, 1% are oil pressers, and 1% are laser beauty equipment. A wide variety of supercritical co2 fluid extraction device options are available to you,
The presence of carbon dioxide in natural gas, synthetic gas and liquid streams has prompted the industrial community to examine the properties of carbon dioxide mixtures with the intent of finding novel methods for removing this acidic impurity. Carbon dioxide is also of interest to researchers because it possesses a readily accessible critical point. This has stimulated studies of the phase behaviour and thermodynamic properties of supercritical fluid mixtures, particularly in systems used in supercritical fluid chromatography (SFC) and supercritical fluid extraction (SFE). For both of these applications, it is important to obtain information pertaining to the vapour-liquid phase boundaries for the carbon dioxide mixtures and their thermodynamic properties over a wide range of pressure and temperature. The (CO: + MeOH) system is of interest to applied research on fluid properties because the pure liquids have widely differing critical points. -- There are many experimental issues associated ...
TY - JOUR. T1 - Selective extraction of phospholipids from whey protein phospholipid concentrate using supercritical carbon dioxide and ethanol as a co-solvent. AU - Sprick, B.. AU - Linghu, Z.. AU - Amamcharla, J. K.. AU - Metzger, L. E.. AU - Smith, J. S.. N1 - Funding Information: We thank Midwest Dairy Foods Research Center (St. Paul, MN) for their financial support. This project is Kansas State Research and Extension contribution number 18-150-J. This work was partially supported by the USDA National Institute of Food and Agriculture, Hatch project 1014344. PY - 2019/12. Y1 - 2019/12. N2 - In recent years, using dairy phospholipids (PL) as functional ingredients has increased because PL have nutritional benefits and functional properties. In this study, a novel 2-step supercritical fluid extraction (SFE) process was used to extract whey protein phospholipid concentrate (WPPC), a dairy co-product obtained during the manufacture of whey protein isolate, for PL enrichment. In the first step, ...
The aim of this work was to evaluate the potential of supercritical carbon dioxide (CO2) to extract Fatty Acid Methyl Esters (FAME) from the microalgae Nannochloropsis oculata (N. oculata) at low temperatures (37 and 55 oC) and pressures (5.9 and 7.6 megapascals (MPa)). A qualitative gas chromatography (GC) analysis showed that the individual FAMEs extracted varied depending on the co-solvent (methanol or hexane) used with supercritical CO2. Using hexane, FAME compounds produced were similar to those extracted with soxhlet extraction alone while longer chain FAME were produced when methanol was the co-solvent. The effects of pressure and temperature variations were shown to be of statistical significance. The chromatograms produced in this work demonstrate that altering one of these parameters (co-solvent, temperature, pressure) can produce different compounds owing to the tunability of the technique.
The effects of organic modifier and temperature on the enantioseparation of 10 triazoles and eight imidazoles, using supercritical fluid chromatography with the Chiralpak AD column, have been investigated in this work. For this purpose four different organic modifiers (methanol, ethanol, 2-propanol and acetonitrile) were evaluated. Only in the case of two compounds could the enantiomeric separation not be achieved with any of the modifiers tested; the rest of compounds were baseline or partially resolved with at least one of the modifiers. The alcohol-type modifiers provided the best results in terms of retention time and resolution. In general, retention increased in the order methanol | ethanol | 2-propanol; moreover it was possible to establish a relationship between the retention and the number of aromatic rings and dioxolane groups in the molecule, that is, the higher the number is, the higher the retention time. From the study of the temperature effect, the enthalpy-entropy compensation was
The first three chapters of the book discuss the various chromatographic and mass spectroscopic techniques now available. Chapters 3-8 cover the complementary methods, based on the combination of mass spectroscopy with various chromatographic techniques such as high-performance liquid chromatography, gas chromatography and supercritical fluid chromatography.
The first three chapters of the book discuss the various chromatographic and mass spectroscopic techniques now available. Chapters 3-8 cover the complementary methods, based on the combination of mass spectroscopy with various chromatographic techniques such as high-performance liquid chromatography, gas chromatography and supercritical fluid chromatography.
Combining state-of-the-art media manufacturing with the industry leading column technology, Viridis Supercritical Fluid Chromatography (SFC) columns bring a new level of reproducibility to the world of laboratory scale purification. Viridis SFC columns are available for analytical and preparative chromatography as Viridis SFC 2-Ethylpyridine columns and Viridis SFC Silica columns. Larger preparative column formats are manufactured using Waters patented Optimum Bed Density (OBD) Technology. 2-Ethylpyridine chemistry is successfully used for a wide range of achiral SFC applications due to its retention, peak shape and selectivity properties. Viridis SFC 2-ethylpyridine columns also provide high reliability and reproducibility and can be used for analytical and preparative applications. Based on Waters long history of chromatographic silica production, the Viridis SFC Silica columns are designed to be highly reproducible and predictable based on tight product specifications and very low metal content.
Supercritical fluid chromatography (SFC) is an orthogonal technique to UHPLC. In recent years, SFC has demonstrated potential for use in the analysis of a broad variety of analytes of different polarities, if modifiers and additives are utilized as additional mobile phase constituents. However, to date, little research has been carried out on ion-exchange separation of highly polar and ionic analytes using SFC. The objective of this work was to investigate the elution characteristics of polar compounds using SFC combined with tandem mass spectrometry. Highly polar and even ionic drugs and metabolites, with a diversity of functional groups such as gamma-hydroxybutyrate (GHB), gamma-butyrolactone, GHB-glucuronide, ethyl sulfate, ethyl glucuronide as well as meldonium and gamma-butyrobetaine, were selected for the study. To investigate the chromatographic behavior of the solutes using SFC, a systematic chromatographic method development workflow including a basic validation in human urine was ...
In this project the photodegradation of 3,5-diamino-6-chloro-N-(2-(methylamino)ethyl)pyrazine-2-carboxamide was studied. A hypothetical degradation pattern for the compound was proposed and the aim of the project was to study the formed secondary photodegradants and to, if possible, structure elucidate some of these compounds. In order to do this, the parent compound was photodegraded in two steps, where a primary photodegradant was isolated using semi-preparative supercritical fluid chromatography (SFC) and then further degraded into the secondary photodegradants.. The photodegradation was first carried out in aqueous solution, where the parent compound was irradiated in UV-A light of 300-400 nm. This resulted in a primary photodegradant with a molecular ion of m/z = 227, where the chloride in position 6 of the pyrazine group had been replaced by a hydroxyl group. During the large scale photodegradation, prior to the preparative purification, the yield of primary photodegradant was very low due ...
A review on the use of packed capillary columns in gas chromatography (GC) is presented. Several articles on the invention of packed capillary columns have been published, as well as on the progress and the development of this technology. Practical applications by this technique have also been studied, especially in the period from 1996 and onwards. A recently developed technique, solvating gas chromatography (SGC), which uses CO2 as the mobile phase combined with a high inlet pressure, has received specific focus.. The use of packed capillary columns in GC has also been evaluated. The technique used to pack these columns has been developed from a similar technology, which have been used for packing of columns, achieving very good separations, for both supercritical fluid chromatography (SFC) and high performance liquid chromatography (HPLC). In the present work, the possibilities of using packed capillary columns in GC, without applying a higher inlet pressure than 5 bar, has been explored. A ...
The goal of this PhD work is to evaluate the possibilities of supercritical fluid chromatography (SFC) in the pharmaceutical analysis. This chromatographic approach will be used to develop analytical methods for numerous types of drugs (including chiral ones) in pharmaceutical formulations. Some inventive strategies will be developed to maximize performance and apply SFC to the widest possible range of molecules. The performance of SFC will be systematically compared to liquid chromatography (LC). In parallel, the PhD candidate will also have the opportunity to couple SFC with single quadrupole(MS), triple quadrupole (MS/MS) and high resolution (QqTOF/MS) mass spectrometers available in our laboratory. This instrumental setup will be used for the determination of drugs and metabolites in complex matrixes, such as biological fluids.. ...
Detection of drugs at low concentration is required in a variety of biological and medical situations, in order to avoid harmful side effects posed by some drug residues. The book details the instrumentation, detection, and application of nano chromatography (that is, any chromatographic and capillary electrophoretic method dealing with the detection of a sample at nano gram per liter or lower) and capillary electrophoresis in the analyses of biological and environmental samples. Methods discussed include: Nano Gas Chromatography, Nano Capillary Electrophoresis, Nano Chiral Chromatography, Micellar Electrokinetic Chromatography, Supercritical Fluid Chromatography, and Nano High Performance Liquid Chromatography.. ...
D6550 Standard Test Method for Determination of Olefin Content of Gasolines by Supercritical-Fluid Chromatography D6591 Standard Test Method for Determination of Aromatic Hydrocarbon Types in Middle Distillates-High Performance Liquid Chromatography Method with Refractive Index Detection. D6750 Standard Test Methods for Evaluation of Engine Oils in a High-Speed, Single-Cylinder Diesel Engine-1K Procedure (0.4 % Fuel Sulfur) and 1N Procedure (0.04 % Fuel Sulfur). D6987/D6987M Standard Test Method for Evaluation of Diesel Engine Oils in T-10 Exhaust Gas Recirculation Diesel Engine. D7347 Standard Test Method for Determination of Olefin Content in Denatured Ethanol by Supercritical Fluid Chromatography. D7422 Standard Test Method for Evaluation of Diesel Engine Oils in T-12 Exhaust Gas Recirculation Diesel Engine. D7484 Standard Test Method for Evaluation of Automotive Engine Oils for Valve-Train Wear Performance in Cummins ISB Medium-Duty Diesel Engine. D7549 Standard Test Method for Evaluation of ...
This application brief successfully demonstrates to convert the compendial normal phase HPLC method for the assay of dapsone tablets to a supercritical fluid chromatography (SFC) method using the Waters ACQUITY UPC2 System.
Surpercritical CO2 reactor Surpercritical CO2 extractor Surpercritical CO2 phase monitor Investigator Supercritical fluid Chromatography System A series of high pressure reactors (Endeavour, HEL, Parr, Autoclave Engineers) REACT IR Several LC-MS Several GC-MS Several flash chromatography separation systems NMR facility Mass spectrometry facility Solvent purification systems
The supercritical carbon dioxide extraction (SC-CO2) of fish oil was studied using the viscera and skin of African catfish as a raw material and the CO2 as supercritical fluid solvent. A central composite design of response surface methodology (RSM) was employed to optimize the SC-CO2 extraction variables. The response variable (Y) oil yield was executed against the four independent variables namely pressure, temperature, flow rate and the soaking time. The statistical analysis showed, pressure was the most significant linear factor on oil yield. Furthermore, the oil yield was varied with the interaction effects of pressure, temperature and flow rate. Optimum points were obtained within the studied variables range at 65°C temperature, 35 MPa pressure, 2.6 mL/min flow rate and 3.6 h soaking time with maximum oil yield 66.96 and 40.6% from viscera and skin, respectively. The principal fatty acids in terms of concentration were oleic and docosahexaenoic acids respectively. The main objective of ...
Colloidal carbon spheres were synthesized by the carbonization of squalane, a nonvolatile hydrocarbon solvent, in supercritical carbon dioxide. Precise pressure modulation of the fluid medium led to size controlled growth of carbon spheres ranging from 300-1500 nm in diameter. This unique synthetic approach of carbonizing a hydrocarbon suspension in supercritical fluid is found to suppress any particle aggregation, resulting in excellent sphere monodispersity. Core-shell hybrid structures of C-Ge were subsequently formed by inducing the growth of 10-40 nm sized germanium nanocrystals from the spheres in a hierarchical bottom-up approach. Extensive characterization of the spheres and nanocrystals was conducted using transmission and scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, Raman and thermogravametric analysis. Assemblies of nanocrystal modified carbon colloids impart outstanding superhydrophobic properties due to the combined nano- and micro-structuring ...
Bilberry seed oils extracted with supercritical carbon dioxide (SC-CO2) for 80 min at 20, 35, and 50 MPa and at 40°, 50° and 60 °C were evaluated to compare the yield, composition, and antioxidant recovery. Analyses of fatty acids, free radical scavenging activity (DPPH), vitamin E and peroxide contents revealed that yield, vitamin E, efficient concentration (EC50), and Peroxide value (PV) varied significantly among the obtained bilberry seed oils, whereas the fatty acid compositions were similar. The oil extracted at 20 MPa and 60 °C had the best recovery of vitamin E and the lowest EC50 and PV. The high levels of vitamin E and polyunsaturated fatty acids, as well as the low ω6/ω3 ratios (|1) and the low PVs in all the extracts suggest bilberry seed oil is a valuable source of bioactive compounds and high potential for use of bilberry by-product extracts in added value foods and nutraceutical products.
TY - JOUR. T1 - Application of supercritical fluid extraction to components of crude drugs and plants. III. Extraction of pigments from lithospermum root and licorice root. AU - Manabe, A.. AU - Tokumori, T.. AU - Sumida, Y.. AU - Yoshida, T.. AU - Hatano, T.. AU - Yazaki, K.. AU - Okuda, T.. PY - 1987/1/1. Y1 - 1987/1/1. UR - http://www.scopus.com/inward/record.url?scp=0023179119&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0023179119&partnerID=8YFLogxK. U2 - 10.1248/yakushi1947.107.7_506. DO - 10.1248/yakushi1947.107.7_506. M3 - Article. C2 - 3694459. AN - SCOPUS:0023179119. VL - 107. SP - 506. EP - 510. JO - Yakugaku Zasshi. JF - Yakugaku Zasshi. SN - 0031-6903. IS - 7. ER - ...
The improved one-pot synthesis of dimethyl carbonate and propylene glycol from propylene oxide, supercritical carbon dioxide, and methanol with potassium bicarbonate as the catalyst has been reported in this paper. As far as we know, it is the first time to use potassium bicarbonate only as the catalyst in the production process which is simple and cheap. Satisfactory conversion rate of propylene oxide and yield of the products could be achieved at the optimized conditions with quite a small amount of by-products. Our new method offers an attractive choice for the production of dimethyl carbonate in large-scale industry efficiently and environmental friendly ...
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This publication offers an outline of simple rules of SFE in addition to in-depth studies of either on- and off-line SFE equipment. The online coupling of SFE with either chromatographic and spectroscopics suggestions has been the topic of loads of examine attempt and is handled intimately. more moderen advancements, corresponding to off-line SFE of sturdy and liquid matrices, are commencing to allure loads of curiosity, and the insurance of those components will turn out of specific price to the analytical chemist. The overseas crew of authors has illustrated those issues with many `state-of-the-art purposes, and every bankruptcy presents a accomplished record of references. For the comfort of the reader, an appendix which includes strain conversion scales and supercritical fluid carbon dioxide density tables looks on the finish of the e-book ...
Aromatherapy is the therapeutic use of pure essential oils through topical application or inhalation. Essential Oils are volatile aromatic substances. The oils are extracted mostly through steam distillation from herbs, flowers, seeds, barks or woody portions of plants, although there are other methods of extraction, including cold pressing (citrus oils), solvent extractions (absolutes) and carbon dioxide extraction.
Analytical Chemistry, Environmental Analysis, Carbon Dioxide Emulsions, Artificial Photosynthesis, Humic Materials, Fluorescence Spectroscopy, Metal Speciation, Vitamin E Oxidation Reduction, Enhanced Oil Recovery. Fluorescence quenching and enhancement phenomena are being utilized to assess binding reactions of metal ions and organic compounds including fulvic and humic acids, Alpha-tocopherol (vitamin E) is being studied to elucidate oxidation and reduction reactions, Liquid and supercritical carbon dioxide droplets are stabilized by particles creating emulsions that have several advantages for carbon dioxide sequestration in geologic formations or the deep oceans and can also be employed for enhanced oil recovery and other valuable applications, Artificial photosynthesis research is being conducted to convert carbon dioxide and water into hydrocarbon fuels. ...
Alternatively, but not commercially significant, is the so-called Henkel process or Raecke process, named after the company and patent holder, respectively. This process involves the rearrangement of phthalic acid to terephthalic acid via the corresponding potassium salts.[7][8] Terephthalic acid can be prepared in the laboratory by oxidizing various para-disubstituted derivatives of benzene, including caraway oil or a mixture of cymene and cuminol with chromic acid.. The use of carbon dioxide overcomes many of the problems with the original industrial process. Because CO2 is a better flame inhibitor than N2, a CO2 environment allows for the use of pure oxygen directly, instead of air, with reduced flammability hazards. The solubility of molecular oxygen in solution is also enhanced in the CO2 environment. Because more oxygen is available to the system, supercritical carbon dioxide (Tc = 31 °C) has more complete oxidation with fewer byproducts, lower carbon monoxide production, less ...
The presence of Alicyclobacillus acidoterrestris, a thermoacidophilic and spore-forming bacterium, in pasteurized acidic juices poses a serious problem for the processing industry. Therefore, the use of other more effective techniques, such as high hydrostatic pressure (HHP) and supercritical carbon dioxide (SCCD), is considered for preserving juices in order to inactivate these bacteria, while reducing the loss of nutrients and sensory quality of juices. On the other hand, HHP and SCCD when combined with a moderately elevated temperature can induce germination of bacterial spores, making them more vulnerable to inactivation. The spore germination can be also induced by nutrients, such as L-alanine or a mixture of asparagine, glucose, fructose and potassium ions (AGFK). The aim of this work was to determine whether applying activating agents: HHP, SCCD and nutrient germinants (L-alanine and the AGFK mixture), could influence the number of spores which start to germinate and how this affects the ...
Michael T. Combs, graduate student in chemistry, recently received the Student Research Award in Supercritical Fluids for an outstanding publication describing research in the use of supercritical fluids in analytical chemistry. The award was presented by the Tri-State and Mid-west Supercritical Fluid Discussion Groups at the Atlanta-Pittsburgh Conference on Analytical Chemistry. The award of $250 plus plaque is presented to an undergraduate or graduate student who served as the primary author of a paper published or accepted for publication during the 1996 calendar year. Judging was based on the technical content, research approach and originality, and writing style. The title of his paper was Comparison of Supercritical Fluoroform and Carbon Dioxide for Extraction of Sulfonamides from Various Food Matrices. Combss thesis research was done under the supervision of L.T. Taylor in the chemistry department ...
RBD Palm Oil refinery Plant for Crude Red Palm Oil/deodorization Palm oil machine is necessary for Corn Germ Oil Plant. With high degree of automation, our oil refining machine can refine about 20 kinds of oil, in a small production line or in industrial continuous microwave dryer and sterilizer equipment.
The objective of the study was to prepare vinblastine microparticles by supercritical antisolvent process using N-methyl-2-pyrrolidone as solvent and carbon dioxide as antisolvent and evaluate its physicochemical properties. The effects of four process variables, pressure, temperature, drug concentration and drug solution flow rate, on drug particle formation during the supercritical antisolvent process, were investigated. Particles with a mean particle size of 121 ± 5.3 nm were obtained under the optimized process conditions (precipitation temperature 60 °C, precipitation pressure 25 MPa, vinblastine concentration 2.50 mg/mL and vinblastine solution flow rate 6.7 mL/min). The vinblastine was characterized by scanning electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, mass spectrometry and dissolution test. It was concluded that physicochemical properties of crystalline vinblastine could be improved by physical modification, such as particle size reduction and generation
Supercritical fluid-assisted deposition of materials on substrates, such as semiconductor substrates for integrated circuit device manufacture. The deposition is effected using a supercritical fluid-based composition containing the precursor(s) of the material to be deposited on the substrate surface. Such approach permits use of precursors that otherwise would be wholly unsuitable for deposition applications, as lacking requisite volatility and transport characteristics for vapor phase deposition processes.
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The possibility of very rapid curing of heterogeneous materials and the formation of unique structure has been presented by many workers. Radiation processing, including microwave heating, is an economical and applicable method of physical and chemical modification of polymeric materials. Beneficial properties of composite materials have been obtained, especially for such polymers [1]. The electric field component of microwave radiation is responsible for dielectric heating mechanisms because it can cause molecular motion by either migration of ionic species or rotation of dipolar species. In this work, definition of the critical state will be revisited, occurrence of supercritical foaming documented, and paths of investigation proposed. INTRODUCTION A lot of attention has been paid in the last two decades to the use of supercritical fluids (SCF) for foaming thermoplastics. The supercritical state is usually defined as a fluid being held at a pressure and temperature above its critical ...
Selama dekade terakhir ionic liquids (ILs) merupakan pelarut alternatif baru dengan campuran (kation dan anion) memiliki sifat fisik dan sifat larutan yang spesifik dan telah terbukti sebagai substituen menjanjikan dari pelarut organik konvensional yang mudah terbakar, mudah menguap, dan beracun dalam berbagai proses. Dalam literatur dan penelitian, senyawa ini sering disebut pelarut ramah lingkungan. Namun, dalam beberapa tahun terakhir persepsi kehijauan berubah secara dramatis sebagai komunitas saintis yang mulai proaktif menilai resiko aplikasi bahan kimia berdasarkan pada seluruh siklus kehidupan. Aplikasi ILs dalam memisahkan komponen aktif dari tumbuhan obat dapat dilakukan dengan dibantu berbagai metode ekstraksi antara lain; heat refluks extraction (IL-HRE), microwave-assisted extraction (IL-MAE), ultrasound-assisted extraction (IL-UAE), IL-assisted ultrahigh pressure extraction (IL-UPE), supercritical fluid extraction (IL-SFE) dan negative-pressure cavitation-assisted extraction ...
Determination of methylmercury in sediments using supercritical fluid extraction and gas chromatography coupled with microwave-induced plasma atomic emission spectrometry ...
Fingerprint Dive into the research topics of Phase behavior of water-insoluble simvastatin drug in supercritical mixtures of chlorodifluoromethane and carbon dioxide. Together they form a unique fingerprint. ...
The processibility of 15 carbohydrates, more or less commonly used, was investigated as excipients in supercritical fluid drying. The focus was on the ability to produce amorphous powder, the stability of the powders towards crystallisation, and the residual water and ethanol content. The aqueous solutions were sprayed into a pressurised carbon dioxide-ethanol mixture flowing cocurrently through a coaxial two-fluid nozzle. The powder characteristics appeared to be influenced by the supersaturation level reached during the SCF-drying process and by the properties of the sugar species, such as water solubility and glass transition temperature, or the solution viscosities. The stability and the residual solvent content of a selected set of sugars and some mixtures were further analysed. The stability of amorphous powders was investigated at 4 degrees C, room temperature, 40 and 50 degrees C. Lactose, maltose, trehalose, raffinose, cyclodextrin, low-molecular-weight dextran and inulin could form ...
Supercritical fluid foaming of semi-crystalline natural-based polymers has been studied using ionic liquids as plasticizing agents, promoting hereafter foaming of the structures. Deep eutectic solvents (DES) are considered today a new generation ionic liquids. DES can be constituted by two natural primary metabolites, namely, aminoacids, organic acids, sugars or choline derivatives and are in this case called natural deep eutectic solvents (NADES). Furthermore, they can even be constituted by an active agent, such as ibuprofen, for example. In this work, we evaluate the possibility of dopping a natural-based polymer, particular a blend of starch and poly-e-carolactone (70:30) with different NADES. The polymers dopped with 10 wt% of each NADES were processed by compression moulding to obtain a homogeneous structure. The compressed mould specimens were tested in order to evaluate their mechanical properties, in tensile mode, and the results suggest that the presence of NADES was able to lower the ...
Are there hydrogen bonds in supercritical methanol and ethanol? Temperature and length scale dependence of tetraalkylammonium ion-amide interaction
Preparation of Active Proteins, Vaccines and Pharmaceuticals as Fine Powders using Supercritical or Near-Critical Fluids Journal Article ...
The ITER project design foresees Supercritical Helium (SHe) forced flow cooling for the main cryogenic components, namely, the superconducting (SC) magnets and cryopumps (CP). Therefore, cold circulators have been selected to provide the required SHe mass flow rate to cope with specific operating conditions and technical requirements. Considering the availability impacts of such machines, it has been decided to perform evaluation tests of the cold circulators at operating conditions prior to the series production in order to minimize the project technical risks. A proposal has been conceptualized, evaluated and simulated to perform representative tests of the full scale SHe cold circulators. The objectives of the performance tests include the validation of normal operating condition, transient and off-design operating modes as well as the efficiency measurement. A suitable process and instrumentation diagram of the test valve box (TVB) has been developed to implement the tests at the required ...
PAN Czytelnia Czasopism, Increase of power and efficiency of the 900 MW supercritical power plant through incorporation of the ORC - Archives of Thermodynamics
Organix South, TheraNeem Organix, Supercritical Extract of Neem Leaf, Immunity and Skin Support, 30 Softgel Capsules $12.90. Neem, Homeopathy, Herbs. Herbal medicines are produced from plants and are based on traditional knowledge. Ayurveda play b...
The application of ultrasonic extraction,microwave extraction,supercritical CO2 extraction,macroporous adsorption resin and so on which researched in recent year in Rheum of purification were summarized.
To obtain the CBD-packed hemp extract from its organic crop, Highland Pharms uses a process called supercritical CO2 extraction. This method eliminates the need for more harmful solvents, while it also, the company says, yields CBD oil of an outstanding purity and efficacy. Those wanting to see for themselves can take their pick from Highland Pharms positively reviewed variety of tinctures - the strongest concentration of which measures up at 1,250 mg - as well as capsules and edibles. And if those potential customers have no idea exactly how much CBD they should be imbibing, then they can get themselves up to speed at the Texas-based companys website, which offers a user-friendly guide to serving sizes and methods of CBD oil intake, among other common queries. ...
QUELL Fish Oil is Supercritical CO2 extracted oils in triglyceride form, manufactured in Germany exclusively for Douglas Laboratories. QUELL Fish Oil is unique among other fish oils for its critical extraction, purity, bioavailability and concentrations ...
Abstract: Amorphous, low-porosity carbon spheres on the order of a few micrometers in size were prepared by carbonization of squalane (C30H62) in supercritical CO2 at 823 K. The spheres were characterized and used as catalysts supports for Pd. Near-edge X-ray absorption fine structure studies of the spheres revealed sp2 and sp3 hybridized carbon. To activate carbons for interaction with a metal precursor, often oxidative treatment of a support is needed. We showed that boiling of the obtained spheres in 28 wt % HNO3 did not affect the shape and bulk structure of the spheres, but led to creation of a considerable amount of surface oxygen-containing functional groups and increase of the content of sp2 hybridized carbon on the surface. This carbon was seen by scanning transmission electron microscopy in the form of waving graphene flakes. The H/C atomic ratio in the spheres was relatively high (0.4) and did not change with the HNO3 treatment. Palladium was deposited by impregnation with Pd acetate ...
Safer extraction strategies embody supercritical CO2 or food-grade ethanol. If you live in a state the place medical marijuana is authorized and available, look for CBD merchandise produced from excessive-resin hashish (rather than low-resin industrial hemp) that are sold in state-licensed dispensaries. CBD, on the other hand, receivedt get you excessive-but research means that it does have a variety of different well being-impacting properties. CBD oil is supposed to harness those well being advantages for those who need to deal with sure situations and illnesses, corresponding to anxiousness, utilizing a natural product. While the science behind CBDs effectiveness for treating anxiousness, pain, and insomnia is still in its infancy, Charlotte Figis inspiring story sounds promising.. There can also be an explainer about the difference between CBD merchandise produced from industrial hemp versus in a lab, and merchandise produced from the whole marijuana plant. You have in all probability ...
In situ investigation of supercritical CO2 assisted impregnation of drugs into a polymer by generic viagra united states high pressure FTIR micro-spectroscopy. Patients who relapse following this approach are treated with cisplatin-based chemotherapy, with retroperitoneal lymph node dissection considered for patients with post-chemotherapy residual masses. Emergent surgery was performed due to sudden severe respiratory failure despite profound liver cirrhosis (Child-Pugh class B). Late transcription also requires an RNA polymerase core-binding co-activator.. The author in this article identifies two liberating discoveries that foster human flourishing: the potential of new knowledge and the importance of living gratitude. The combination of ribotyping and PFGE identified two large epidemic clones, which were called 691.5/PFGE-G and 595.7/PFGE-A. Because small colonic tumours may not be visualized or palpated during laparoscopy, location of generic viagra trusted pharmacy the lesion must be ...
Aerogels are ultra-porous and nanostructured materials with a wide range of applications. Bio-aerogels is a new generation of polysaccharide-based aerogels. These fast developing materials are particularly promising for their environmental friendliness and biocompatibility. Nowadays, the production of bio-aerogels in the form of monoliths is mastered. To optimize their manufacturing process and to meet specific application needs (pharmaceutical, food, absorption or adsorption, etc.), aerogels must be in the form of particles. This work focused on the preparation and characterization of cellulose aerogel beads and was conducted in the framework of the European project Nanohybrids. Two main objectives were achieved. The first was the preparation and understanding of the properties of new materials while reducing their production costs. Two types of porous materials were produced and studied: • Cellulose-based xerogels (obviating drying under supercritical CO2), with properties comparable to those of
Previous work (M. Sagisaka, et al. Langmuir 31 (2015) 7479-7487), showed the most effective fluorocarbon (FC) and hydrocarbon (HC) chain lengths in the hybrid surfactants FCm-HCn (sodium 1-oxo-1-[4-(perfluoroalkyl)phenyl]alkane-2-sulfonates, where m = FC length and n = HC length) were m and n = 6 and 4 for water solubilization, whereas m 6 and n 6, or m 6 and n 5, were optimal chain lengths for reversed micelle elongation in supercritical CO2. To clarify why this difference of only a few methylene chain units is so effective at tuning the solubilizing power and reversed micelle morphology, nanostructures of water-in-CO2 (W/CO2) microemulsions were investigated by high-pressure small-angle neutron scattering (SANS) measurements at different water-to-surfactant molar ratios (W0) and surfactant concentrations ...
A velvety texture that nourishes facial skin deep down during sleep. It increases density and uniformity, restructures and volumises for a more youthful, fresher appearance. 50ML ACTIVE INGREDIENTS: The active principle of Pistacia lentiscus resin crystals: obtained using the Green Technology supercritical CO2 extracti
b)Exemptions. (1) A limited permit for interstate movement shall not be required for genetic material from any plant pest contained in Escherichia coli genotype K-12 (strain K-12 and its derivatives), sterile strains of Saccharomyces cerevisiae, or asporogenic strains of Bacillus subtilis, provided that all the following conditions are met: (i) The microorganisms are shipped in a container that meets the requirements of § 340.8(b)(3); (ii) The cloned genetic material is maintained on a nonconjugation proficient plasmid and the host does not contain other conjugation proficient plasmids or generalized transducing phages; (iii) The cloned material does not include the complete infectious genome of a known plant pest; (iv) The cloned genes are not carried on an expression vector if the cloned genes code for: (A) A toxin to plants or plant products, or a toxin to organisms beneficial to plants; or (B) Other factors directly involved in eliciting plant disease (i.e., cell wall degrading enzymes); or ...
0024] The H.264 encoder encodes a current macroblock that is entirely within the static areas as having no difference from a corresponding macroblock in a preceding frame by using a macroblock that is created without comparing the current macroblock to the corresponding preceding macroblock. For example, in the H.264 context, a static macroblock for which all of the following conditions are fulfilled may be used to encode a macroblock that is entirely within an area identified as static by the metadata: [0025] 1) CodedBlockPatternLuma and CodedBlockPatternChroma are both equal to 0, and, [0026] 2) either of the following conditions are fulfilled: [0027] a. mb_type is equal to P_Skip or P_L0--16×16 and weighted_pred_flag is not equal to 1, or, [0028] b. mb_type is equal to B_Skip, B_Direct 16×16, B_L0--16×16, or B_L1--16×16 and weighted_bipred_idc is not equal to 1; [0029] 3) only a single list X for X=0 or 1 (List 0 or List 1) is used in the inter prediction process for the macroblock, ...
The drug does not affect the ability to drive vehicles and work with mechanisms.. If you have any of the following conditions / risk factors, the benefits of using Lillow and the possible risk should be weighed individually before using this drug. In case of aggravation, worsening or first occurrence of any of the following conditions or risk factors, it is recommended to consult a doctor. The doctor must decide whether its necessary to stop using COCs.. Based on the results of epidemiological studies, there is a link between the use of birth control pills and an increased risk of venous and arterial thrombotic and thromboembolic diseases, such as myocardial infarction, stroke, deep vein thrombosis and pulmonary embolism. The below-listed conditions are very rare.. 1. Venous thromboembolism:. Venous thromboembolism - acute vein thrombosis and / or pulmonary embolism can occur when using any COCs.. The risk of venous thromboembolism is very high during the first year of use of Lillow. The ...
|p|This paper re-examines most public and in-house corrosion data on the effects of six typical impurities to advance the fundamental understanding of how pipeline steels corrode in sc-CO2 environments and identify knowledge gaps for further investigations.|/p|
Smoore Researchs new generation of ceramic core technology - FEELM metal film atomization, using ceramics as a carrier, and high-temperature forged ceramics, a large number of honeycomb capillary pores inside, which is more conducive to the uniform penetration of vape juice and heating atomization, while retaining and enhancing the original characteristics of the ceramic core pure and rich taste.. The core technology of FEELM is to completely get rid of the shackles of the traditional heating wire. The metal film is covered by a special process at the bottom of the ceramic, and the S type distribution is used to greatly improve the overall heating performance.. After comparative analysis of the data, it is concluded that the amount of vapor generated by FEELM metal film atomization technology is 52% higher than that of traditional cotton core. This breakthrough vapor generation makes the transmission efficiency of nicotine much higher than that of traditional technology as 56%. For the ...
Apparatus and methods are described for removing contaminants from an article using a supercritical or near supercritical solvent fluid held at substantially constant pressure in a pressure vessel. The article to be cleaned is first contacted with a solvent fluid in which the contaminant is soluble at a first supercritical or near-supercritical temperature. The
A method for depositing one or more materials on a substrate, such as for example, a semiconductor substrate that includes providing the substrate; applying a polymer film to at least a portion of a surface of the substrate; and exposing the semiconductor substrate to a supercritical fluid containing at least one reactant for a time sufficient for the supercritical fluid to swell the polymer and for the at least one reactant to penetrate the polymer film. The reactant is reacted to cause the deposition of the material on at least a portion of the substrate. The substrate is removed from the supercritical fluid, and the polymer film is removed. The process permits the precise deposition of materials without the need for removal of excess material using chemical, physical, or a combination of chemical and physical removal techniques.
The main fact in the subcritical phase is exponential decay. That is, when p , pc, the probability that a specific point (for example, the origin) is contained in an open cluster (meaning a maximal connected set of open edges of the graph) of size r decays to zero exponentially in r. This was proved for percolation in three and more dimensions by Menshikov (1986) and independently by Aizenman & Barsky (1987). In two dimensions, it formed part of Kestens proof that pc = 1/2.[5] The dual graph of the square lattice ℤ2 is also the square lattice. It follows that, in two dimensions, the supercritical phase is dual to a subcritical percolation process. This provides essentially full information about the supercritical model with d = 2. The main result for the supercritical phase in three and more dimensions is that, for sufficiently large N, there is[clarification needed] an infinite open cluster in the two-dimensional slab ℤ2 × [0, N]d − 2. This was proved by Grimmett & Marstrand ...
Stabilised Bimetallic Metal Nanoparticles in Tailor-made Carbon Nanoreactors as Catalysts for Continuous-Flow Biomass Valorisation with Supercritical Fluids Dr. R. A. Bourne,a Dr. T. W. Chamberlain,a,b Dr. U. Hintermair,c & Dr. C. D. Smithd aSchool of Process, Environmental and Mechanical Engineering, University of Leeds, bSchool of Chemistry, University of Nottingham, cCentre for Sustainable Chemical Technologies, University of Bath, dSchool…
Associate Professor of Chemical Engineering Dept., IST-ULisboa - Cited by 3,392 - Process Integration & Optimization and Supercritical Fluids
7: 911-919 Crossref Mechanical statistics and download measuring democracy a bridge between of fetal aid rounds for passport collection engineeringQingwei Zhang, Vadym N. Mochalin, Ioannis Neitzel, Kavan Hazeli, Junjie Niu, Antonios Kontsos, Jack G. Lelkes, Yury GogotsiBiomaterials. Elahe Masaeli, Mohammad Morshed, Parsa Rasekhian, Saeed Karbasi, Khadije Karbalaie, Fereshte Karamali, Daryoush Abedi, Shahnaz Razavi, Abbas Jafarian-Dehkordi, Mohammad Hossein Nasr-Esfahani, Hossein BaharvandJournal of Biomedical Materials Research Part A. 7: 1907-1918 Crossref Architecture and cattle of brief overnight media for department portfolio predicted via regional CO2 including and department promoting environmental environment. NettiThe Journal of Supercritical Fluids. 67: 114-122 download measuring democracy a bridge between scholarship and politics democratic transition and success and program of therapy supporting financial of storage business from series Library Evenchelys macruraAnguchamy Veeruraj, ...
page) at the University of Southampton:. Position #1: Post-Doctoral Research Fellowship in nuclear magnetic resonance in the research group of Dr Giuseppe Pileio, in collaboration with Prof Malcolm H Levitt. The project, funded by EPSRC(UK), concerns the development of hardware and methodology that combines supercritical fluids with long-lived states NMR and dissolution-DNP to prolong the storage of hyperpolarised spin order and allow it to be transported remotely from the production site. The successful candidate will be mainly responsible of the hardware development side of the project and will work together with a PhD student and another Research Fellow, both already appointed. Furthermore, the project is done in partnership with Jasco, a UK based company specialising in supercritical-fluids. The position is tenable from 13 Feb 2017 (or as soon as possible thereafter) with initial appointment for 2 years and there are already enough funds for a further extension of 1 year or more, subject to ...
Smith, R. D.; Fjeldsted, J. C.; Lee, M. T.; Felix, W.D. (1982). "Capillary Column Supercritical Fluid Chromatography-Mass ... and Supercritical Fluid Chromatography-MS (1983). He was the recipient of the 2013 Award for a Distinguished Contribution in ... Matson, D.W.; Petersen, R.C.; Smith, R.D. (1986). "Formation of Silica Powders from the Rapid Expansion of Supercritical Fluid ... Matson, D.W.; Petersen, R.C.; Smith, R.D. (1986). "Rapid Precipitation of Low Vapor Pressure Solids from Supercritical Fluid ...
"Supercritical fluid extraction of quinolizidine alkaloids from Sophora flavescens Ait. and purification by high-speed counter- ... current chromatography" (PDF). Journal of Chromatography A. 1145: 123-127. doi:10.1016/j.chroma.2007.01.080. A review on ... by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry". Journal of Pharmaceutical and ...
D. Klink; O. Schmitz (2016). "SFC-APLI-(TOF)MS: Hyphenation of Supercritical Fluid Chromatography to Atmospheric Pressure Laser ... Couplings with separation methods like Supercritical Fluid Chromatography (SFC) and Chip-Electrospray (Chip-ESI) have also been ... Thiäner, Jan B.; Achten, Christine (2017-03-01). "Liquid chromatography-atmospheric pressure laser ionization-mass spectrometry ... in particular in applications with liquid chromatography (LC-MS) .The selectivity of APLI is one factor contributing to the ...
Nexera UC fully automated supercritical fluid extraction - supercritical fluid chromatography - mass spectrometry system; ... AQUITY® QDa™ mass detector for chromatography; Bronze - AB Sciex LLC - CESI-MS system using capillary electrophoresis combined ... 2003: Gold - Dionex Corp - ICS 2000 Reagent-Free ion chromatography system; Silver - Thermo Electron Corp - Finnigan LTQ hybrid ... 2012: Gold - Waters - ACQUITY UPC (UltraPerformance Convergence Chromatography™); Silver - Bruker - SCION TQ triple quadrupole ...
... consumption High product concentration High productivity Continuous process This system is useful in the supercritical fluid ... True moving bed chromatography (TMBC) is only a theoretical concept. Its simulation, SMBC is achieved by the use of a ... A continuous chromatography technique to overcome the two fraction limit and to apply gradients is multicolumn countercurrent ... Chromatography Multicolumn countercurrent solvent gradient purification Bailly, M. and Nicoud, R.-M. (LSGC-ENSIC, 1, rue ...
... supercritical fluid chromatography, laboratory informatics, rheometry and microcalorimetry. The business was started by James ( ... The company's first major break came when Dow Chemical bought one of Waters' first gel permeation chromatography instruments, ... Waters markets to the laboratory-dependent organization in these market areas: liquid chromatography, mass spectrometry, ... Empower chromatography and MassLynx mass spectrometry software, Oasis sample preparation products, NuGenesis lab management ...
In 1984, he co-founded Lee Scientific to develop and market supercritical fluid chromatographic instrumentation and, in 1991, ... Tswett Chromatography Medal (1984), the Keene P. Dimick Chromatography Award (1988), the American Chemical Society Award in ... the Russian Tswett Chromatography Medal (1992), the Martin Gold Medal (1996), the Latin-American Chromatography Congress Medal ... He is a co-founder of Torion Technologies, which markets a hand-portable gas chromatography-mass spectrometry system. He is ...
2009). "Investigation of supercritical fluid extraction of puerarin from Pueraria Lobata". Journal of Food Process Engineering ... Journal of Chromatography A. Elsevier. 923 (1 - 2): 255-262. doi:10.1016/S0021-9673(01)00996-7. PMID 11510548. Kintzios, ...
... chromatography (SFC) can be used on an analytical scale, where it combines many of the advantages of high ... Recent supercritical fluids have shown the capability to reduce particles up to a range of 5-2000 nm. Supercritical fluids act ... "What is a supercritical fluid?". Budapest University of Technology and Economics. Retrieved 2014-06-26. "Supercritical Fluid ... gases and supercritical fluids. In addition, there is no surface tension in a supercritical fluid, as there is no liquid/gas ...
... column chromatography preparative-high performance liquid chromatography super critical fluid chromatography high speed counter ... chromatography a combination of vacuum flash silica gel chromatography and flash C8 column chromatography flash chromatography ...
... carbon dioxide: Supercritical fluid chromatography, a form of liquid chromatography using supercritical carbon ... a Generation IV nuclear reactor concept that uses supercritical water as the working fluid Supercritical flow, where flow ... similar to freeze drying Supercritical fluid, a substance at a temperature and pressure above its thermodynamic critical point ... the bifurcation is called supercritical Pitchfork bifurcation, in mathematics, similar to Hopf bifurcation Super Critical, an ...
... gas chromatography) UPLC (ultra performance liquid chromatography) Supercritical fluid chromatography Electrophoresis Ligand ... gas chromatography-mass spectrometry) LC-DAD (liquid chromatography-diode array detection) CE-MS (capillary electrophoresis- ... The first studies measuring drugs in biological fluids were carried out to determine possible overdosing as part of the new ... Initially, nonspecific assays were applied to measuring drugs in biological fluids. These were unable to discriminate between ...
Simulated distillation of high-boiling petroleum fractions by capillary supercritical fluid chromatography and vacuum thermal ... 7, 1992 The Scientist, June, 1990 Robert Brownlee Foundation Chromatography Forum. ... to form the Bay Area Chromatography Colloquium. Bob Stevenson is quoted as saying in his Nine Lives of the California ... a manufacturer of columns and pumps for high performance liquid chromatography systems. Bob Brownlee took the initiative "along ...
Supercritical fluid chromatography[edit]. Further information: Supercritical fluid chromatography. Supercritical fluid ... or a supercritical fluid (supercritical-fluid chromatography, SFC). The mobile phase consists of the sample being separated/ ... Thin layer chromatography (TLC)[edit]. Further information: Thin layer chromatography. Thin layer chromatography (TLC) is a ... Gas chromatography[edit]. Further information: Gas chromatography. Gas chromatography (GC), also sometimes known as gas-liquid ...
Journal of Chromatography A. 1152 (1-2): 234-246. doi:10.1016/j.chroma.2007.02.046. U.S.EPA Method 3560 Supercritical Fluid ... Yeo, S.; Kiran, E. (2005). "Formation of polymer particles with supercritical fluids: A review". J. Supercrit. Fluids. 34: 287- ... Supercritical carbon dioxide (sCO 2) is a fluid state of carbon dioxide where it is held at or above its critical temperature ... Supercritical CO 2 could be used as a working fluid in enhanced geothermal systems. Possible advantages compared to water ...
There are different tacit understandings of supercritical fluids. For example, "a fluid is considered to be 'supercritical' ... adsorption from supercritical gases in extraction processes and chromatography. Besides, knowledge of gas/solid interface ... Supercritical Adsorption also referred to as the adsorption of supercritical fluids, is the adsorption at above-critical ... Fabrication of block copolymer monolayers by adsorption from supercritical fluids: A versatile concept for modification and ...
... enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography ... Detection in body fluidsEdit. Main article: Cannabis drug testing. THC and its 11-OH-THC and THC-COOH metabolites can be ... by reverse-phase high-performance liquid chromatography estimation.. ... detected and quantified in blood, urine, hair, oral fluid or sweat using a combination of immunoassay and chromatographic ...
History of chromatography Supercritical fluid chromatography Berthod, Alain; Maryutina, Tatyana; Spivakov, Boris; Shpigun, Oleg ... Countercurrent chromatography (CCC, also counter-current chromatography) is a form of liquid-liquid chromatography that uses a ... Unlike column chromatography and high-performance liquid chromatography, countercurrent chromatography operators can inject ... Comparing multilayer toroidal coil chromatography with centrifugal partition chromatography". Journal of Chromatography A. 1218 ...
... (SFC) is a form of normal phase chromatography that uses a supercritical fluid such as ... Taylor, Larry T. (2009). "Supercritical fluid chromatography for the 21st century". The Journal of Supercritical Fluids. 47 (3 ... "Integration of supercritical fluid chromatography into drug discovery as a routine support tool". Journal of Chromatography A. ... supercritical fluid chromatography is sometimes called convergence chromatography. SFC is used in industry primarily for ...
Determination of Uranium by Packed-Column Supercritical Fluid Chromatography - CEA Saclay Robust liquid chromatography-tandem ... and flash chromatography. Interchim developed a unique flash chromatography system (PuriFlashEvo430 - integrated functions). ... The activity in Chromatography spans HPLC, LC/MS, FPLC, MPLC - GC, GC/MS, GPC, GFC - RMN - AA, IR, ICP, UV - SPE. Interchim ... The activity started with distribution of fine chemicals, then chromatography and Biology. Production was developed as well, in ...
"Optimization of Supercritical Fluid Consecutive Extractions of Fatty Acids and Polyphenols from Vitis Vinifera Grape Wastes". ... In chemical analysis, fatty acids are separated by gas chromatography of methyl esters; additionally, a separation of ... This fatty acid composition results in a more fluid cell membrane but also one that is permeable to various ions (H+ & Na+), ... fluid, heavy whipping nutritiondata.com → Egg, yolk, raw, fresh Retrieved on August 24, 2009 "09038, Avocados, raw, California ...
January 2015). "Optimization of supercritical fluid consecutive extractions of fatty acids and polyphenols from Vitis vinifera ... In chemical analysis, fatty acids are separated by gas chromatography of methyl esters;[6] additionally, a separation of ... This fatty acid composition results in a more fluid cell membrane but also one that is permeable to various ions (H+ & Na+), ... of fatty acids or methyl esters including positional and geometric isomers by alumina argentation thin-layer chromatography". ...
Supercritical carbon dioxide extraction and mathematical modeling of extraction process". The Journal of Supercritical Fluids. ... "Characterization of volatile compounds from ethnic Agave alcoholic beverages by gas chromatography-mass spectrometry". Food ...
In supercritical electric fields, the field strength overbears the surface tension and a fluid jet emanates from the droplet ... Many technical applications of biological objects like proteins, viruses or bacteria such as chromatography, optical ... Core shell fibers of nano particles with fluid cores and solid shells can be used to entrap biological objects such as proteins ...
"Supercritical fluid extraction of kava lactones from Piper methysticum (kava) herb". Hüthig GmbH. doi:10.1002/jhrc.1240201007/ ... using high performance thin layer chromatography (HPTLC)". Food Chemistry. 151: 554-560. doi:10.1016/j.foodchem.2013.11.120. ... Pharmaceutical and herbal supplement companies extract kavalactones from the kava plant using solvents such as supercritical ...
High Performance Liquid Chromatography (HPLC), size exclusion chromatography, sarta supercritical fluid chromatography.[9][10] ... Size exclusion chromatography[besut , besut sumber]. Size exclusion chromatography, utawi ugi sami kaliyan gel permeation utawi ... High performance liquid chromatography[besut , besut sumber]. High performance liquid chromatography (HPLC) gadhah prinsip ... 1.1 Kromatografi Cair (Liquid Chromatography) *1.1.1 Reverse phase chromatography. *1.1.2 High performance liquid ...
Oxidation of alkyl aromatics". Journal of Supercritical Fluids. Elsevier. 12 (3): 255-260. doi:10.1016/S0896-8446(98)00084-9. ... permanent dead link] Smith, Roger; Young, E.; Sharp, B. "Superheated water chromatography - flame ionization detection" (PDF). ... Clifford, Tony (Nov 5-8, 2006). "Separations using superheated water". 8th International Symposium on Supercritical Fluids. ... by either extraction alone or extraction linked to supercritical or wet oxidation. Superheated water, along with supercritical ...
... and Supercritical Carbon Dioxide method but it is technically known as supercritical fluid extraction. The supercritical CO2 ... many coffee companies choose to employ High-performance liquid chromatography to quantitatively measure how much caffeine ... The extractor is then sealed and supercritical CO2 is forced into the coffee at pressures of 1,000 pounds per square inch ( ... ISBN 978-94-010-4947-4. Lee, S.; Park, M.K.; Kim, K.H.; Kim, Y.-S. (September 2007). "Effect of Supercritical Carbon Dioxide ...
"Optimization of Supercritical Fluid Consecutive Extractions of Fatty Acids and Polyphenols from Vitis Vinifera Grape Wastes". ... Jingren He, Celestino Santos-Buelga, Nuno Mateus and Victor de Freitas, Journal of Chromatography A, Volume 1134, Issues 1-2, ... Journal of Chromatography A. 874 (1): 101-9. doi:10.1016/S0021-9673(00)00086-8. PMID 10768504.. ...
The Journal of Supercritical Fluids. 129: 16-27. doi:10.1016/j.supflu.2017.03.014.. ... or more reliably by gas chromatography combined with mass spectrometry (GC/MS). Liquid chromatography (LC) techniques are also ... Supercritical solvent extraction with carbon dioxide is an alternative technique. Once extracted, isolated components can be ... Rovetto L, Aieta N (November 2017). "Supercritical carbon dioxide extraction of cannabinoids from Cannabis sativa L.". ...
"Optimization of Supercritical Fluid Consecutive Extractions of Fatty Acids and Polyphenols from Vitis Vinifera Grape Wastes". ... Liquid liquid extraction can be also performed or countercurrent chromatography. Solid phase extraction can also be made on C18 ... Phosphomolybdic acid is used as a reagent for staining phenolics in thin layer chromatography. Polyphenols can be studied by ... Concentration can be made by ultrafiltration.[72] Purification can be achieved by preparative chromatography. ...
Supercritical fluid extraction: A relatively new technique for extracting fragrant compounds from a raw material, which often ... Creating perfumes through reverse engineering with analytical techniques such as Gas chromatography-mass spectrometry (GC/MS) ... employs Supercritical CO2. Due to the low heat of process and the relatively nonreactive solvent used in the extraction, the ...
The product of this process is called a "concrete." Supercritical fluid extraction: A relatively new technique for extracting ... Creating perfumes through reverse engineering with analytical techniques such as Gas chromatography-mass spectrometry (GC/MS) ... fragrant compounds from a raw material, which often employs Supercritical CO2. Due to the low heat of process and the ...
When speciation of the organics is required for troubleshooting or design purposes, liquid chromatography-organic carbon ... sub and super critical boilers), and specialty applications such as research laboratories. The "ultrapure water" term became ... or as make-up to cooling fluid in some critical applications. UPW is even sometimes used as a humidification source for the ... and super critical oxidation. Typical equations showing persulfate generation of hydroxyl radicals follows. S2O8-2 + hν (254 nm ...
... as well as crystallites or other junctions that remain intact within the extending fluid. Virtually any fluid can be used as an ... acid Agarose gel electrophoresis Food rheology Gel electrophoresis Gel filtration chromatography Gel permeation chromatography ... When solvent removal occurs under supercritical conditions, the network does not shrink and a highly porous, low-density ... It is a type of non-Newtonian fluid. By replacing the liquid with gas it is possible to prepare aerogels, materials with ...
Supercritical fluid chromatography (SFC) is a form of normal phase chromatography that uses a supercritical fluid such as ... Taylor, Larry T. (2009). "Supercritical fluid chromatography for the 21st century". The Journal of Supercritical Fluids. 47 (3 ... "Integration of supercritical fluid chromatography into drug discovery as a routine support tool". Journal of Chromatography A. ... supercritical fluid chromatography is sometimes called convergence chromatography. SFC is used in industry primarily for ...
The use of supercritical fluids in analytical chemistry is still grow- ing. More and more analysts are discovering the ... Analytical Chemistry Chromatographie Chromatography Extraction Extraktion (Chem.) Supercritical Fluids chemistry Editors and ... Supercritical fluid chromatography (SFC) has become better established and the development of this technique has been ... Stationary Phases for Packed Column Supercritical Fluid Chromatography Colin F. Poole, John W. Oudsema, Thomas A. Dean, Salwa K ...
Japan Supercritical Fluid Chromatography (Sfc) Industry Market Research Report 2017. India Supercritical Fluid Chromatography ( ... Global Supercritical Fluid Chromatography (Sfc) Industry Market Research Report 2017. China Supercritical Fluid Chromatography ... United States Supercritical Fluid Chromatography (Sfc) Industry Market Research Report 2017. News • Feb 27, 2017 01:54 GMT ... The United States Supercritical Fluid Chromatography (Sfc) Industry Market Research Report 2017 is a professional and in-depth ...
The basic principles of liquid chromatography can be applied to supercritical fluid chromatography (SFC). ... Although supercritical fluid chromatography (SFC) is not a new technique, preparative SFC is becoming increasingly more popular ... Supercritical fluid chromatography can be run at increased flow rates making isolations faster and increasing throughput. ... Basic principles for the separation of compounds from mixtures using supercritical fluid chromatography (SFC) are similar to ...
USA Home > Product Directory > Analytical/Chromatography > HPLC > SFC (Supercritical Fluid Chromatography) Columns > GreenSep ...
Supercritical fluid chromatography columns. We provide preparative chromatography columns adapted to the high pressure ... SupersepTM , Supercritical fluid chromatography systems. Our Supersep™ preparative SFC systems enable fast, robust, ... Your process is greener thanks to the use of supercritical CO2 decreasing the amount of organic solvent required by 5 to 20 ...
The European Supercritical fluid chromatography reagents report defines and segments the concerned market in Europe with ... In super critical fluid chromatography, a supercritical fluid is used as the mobile phase. A super critical fluid is a ... North America Super Critical Fluid Chromatography (Reagents) Market Super Critical Fluid Chromatography Reagents-North America ... Europe is the second-largest market for supercritical fluid chromatography reagents. The demand for the supercritical fluid ...
46] Liu Y. Fluid and supercritical CO 2 as eluent in metal chelate chromatography. [52] Jentoft RE. Vazquez MJ. J Chromatogr ... Fifth International Symposium on Supercritical Fluid Chromatography and Extraction. Trends Anal Chem 1994. Packed-column ... Abstract Supercritical fluid chromatography (SFC) combines the high diffusion coefficients of gas chromatography (GC) and the ... fluid chromatography. Homogeneous catalysis in supercritical fluids. Journal of Chromatography. Caruso JA. Vela NP. Selby M. ...
Chromatography Data System. ChromNAV Ver. 2. *1 Stop valve unit *2 Solvent switching unit *3 Mixing unit *4 10 position-11port ... 2. M. Bounoshita, T. Kanomata, CHROMATOGRAPHY, 2011, 32, 23-32.. 3. O. A. Adegoke, Afr.J. Pure Appl.Chem., 2012, 6 (14), 129- ... Ms Iijima is a member of the chromatography separations team at JASCO Corporation main applications laboratory in Tokyo Japan. ... "Practical High-Performance Liquid Chromatography", 4th ed., John Wiley & Sons , 2004, 92 and 279-282. ...
nterest in supercritical fluid chromatography (SFC) applications is growing due to its ability to reduce analysis times, ... Rapid Peptide Separation by Supercritical Fluid Chromatography with Mass Spectrometry. By DJ Tognarelli ... Home / Applications / Rapid Peptide Separation by Supercritical Fluid Chromatography with Mass Spectrometry ... The separation column was a Princeton Chromatography 2-Ethylpyrindine column (4.6 mm ID x 250 mm L, 5 mm, 60A). The standard 5 ...
In this report, the United States Supercritical Fluid Chromatography (SFC)... ... 104 Pages Report] Check for Discount on United States Supercritical Fluid Chromatography (SFC) System Market Report 2017 report ... United States Supercritical Fluid Chromatography (SFC) System Market Report 2017. 1 Supercritical Fluid Chromatography (SFC) ... 7 Supercritical Fluid Chromatography (SFC) System Manufacturing Cost Analysis. 7.1 Supercritical Fluid Chromatography (SFC) ...
... supercritical fluid chromatography, capillary electrophoresis, thin-layer chromatography and high pressure liquid ... 23rd Montreux Symposium on Liquid Chromatography-Mass Spectrometry, Supercritical Fluid Chromatography-Mass Spectrometry, ... Development and application of supercritical fluid extraction-immunoaffinity chromatography procedure Bou Carrasco, Pilar; Díez ... Sample records for CROMATOGRAFIA DE FLUIDO SUPERCRITICO (supercritical fluid chromatography). from WorldWideScience.org. Sample ...
Supercritical Fluid Chromatography (SFC) received an uneasy welcome, mainly because of the lack of commercially available ... the application to chromatography of the critical phenomena of compressed gases or overheated liquids as supercritical fluids ... Extraction with supercritical fluids (SFs) was welcome from the very beginning. In the present paper, ... High-Performance Liquid Chromatography or even Thin Layer Chromatography. The present status and future perspectives for SFC ...
Read reviews and compare manufacturers of Supercritical Fluid Chromatography > Accessories products in the SelectScience ... such as supercritical fluid chromatography (SFC), HPLC, supercritical fluid extraction (SFE), particle formation, reactions, so ... gas chromatography. Refillable moisture traps are constructed from ... Read more... ...
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"Selectivity in Tuning in Packed Column Supercritical Fluid Chromatography." Supercritical Fluid Chromatography with Packed ... "Selectivity in Tuning in Packed Column Supercritical Fluid Chromatography." Supercritical fluid chromatography with packed ... Selectivity in tuning in packed column supercritical fluid chromatography. Supercritical fluid chromatography with packed ... Selectivity in tuning in packed column supercritical fluid chromatography. Supercritical fluid chromatography with packed ...
Supercritical fluid chromatography (SFC) coupled with triple quadrupole mass spectrometry was applied to the profiling of ... as compared to the conventional high-performance liquid chromatography. The applicability of our method for the analysis of SEs ...
Journal of chromatography. A 2014-12-3 Comparison of liquid chromatography and supercritical fluid chromatography coupled to ... and ultra-high performance supercritical fluid chromatography (UHPSFC)) were tested in combination with simple MS detector. To ... At the end, the proposed strategy of optimized chromatography combined with simple MS device has been shown to potentially ... For this purpose, two modern chromatographic approaches (ultra-high pressure liquid chromatography (UHPLC) ...
In this report, the United States Supercritical Fluid Chromatography (Sfc)... ... 98 Pages Report] Check for Discount on United States Supercritical Fluid Chromatography (Sfc) Market Report 2017 report by ... 1 Supercritical Fluid Chromatography (Sfc) Overview. 1.1 Product Overview and Scope of Supercritical Fluid Chromatography (Sfc) ... 7 Supercritical Fluid Chromatography (Sfc) Manufacturing Cost Analysis. 7.1 Supercritical Fluid Chromatography (Sfc) Key Raw ...
Separation of coenzyme Q10 in CPO and palm fibre oil was carried out using supercritical fluid chromatography with ultra violet ... Separation of Coenzyme Q10 in Palm Oil by Supercritical Fluid Chromatography Ng M. Han, Choo Y. May, Ma A. Ngan, Chuah C. Hock ... Separation of coenzyme Q10 in CPO and palm fibre oil was carried out using supercritical fluid chromatography with ultra violet ...
... and one esterified form of α-tocopherol acetate were analyzed using ultra-high-performance supercritical fluid... ... Ultra-High-Performance Supercritical Fluid Chromatography. The ultra-high-performance supercritical fluid chromatography system ... Ultra-high-performance supercritical fluid chromatography Ultra-high-performance liquid chromatography Liquid-liquid extraction ... Oberson JM, Campos-Gimenez E, Riviere J, Martin F (2018) Application of supercritical fluid chromatography coupled to mass ...
Supercritical Fluid Chromatography Introduction: Supercritical Fluid Chromatography (SFC) is a hybrid of gas and liquid ... Supercritical Fluid Chromatography Introduction : Supercritical Fluid Chromatography (SFC) is a hybrid of gas and liquid ... 421-821-chapter-29-30 - Supercritical Fluid Chromatography.... This preview shows document pages 1 - 5. Sign up to view the ... chromatography that combines some of the best features of both Supercritical Fluid exist at temperatures and pressures above ...
Quantification of 3-n-butylphthalide in beagle plasma samples by supercritical fluid chromatography with triple quadruple mass ... Quantification of 3-n-butylphthalide in beagle plasma samples by supercritical fluid chromatography with triple quadruple mass ... A high-throughput, rapid, sensitive, environmentally friendly, and economical supercritical fluid chromatography with triple ... The mobile phase comprised supercritical carbon dioxide/methanol (90:10, v/v) at a flow rate of 1.5 mL/min, the compensation ...
The differences in matrix effects between supercritical fluid chromatography and reversed phase liquid chromatography coupled ... The increasing popularity of supercritical fluid chromatography (SFC) in combination with electrospray ionization mass ...
... fluid extraction of pesticides in sediment from the Okavango Delta, Botswana, and determination by gas chromatography with ... Fluid. 31 (2) 149-157. [ Links ]. REVERCHON E and DE MARCO I (2006) Supercritical fluid extraction of natural matter. J. ... Fluid. 38 (2) 167-180. [ Links ]. CAMEL V (1998) Supercritical fluid extraction as a useful method for pesticides determination ... QUAN C. LI S, TIAN S, XU H, LIN A and GU L (2004) Supercritical fluid extraction and clean-up of organochlorine pesticides in ...
Use of Amine Additive in the Sample Diluent in a Supercritical Fluid Chromatography (SFC) Purification. @media screen and (max- ... Liquid Chromatography (LC/HPLC)Gas Chromatography (GC)Sample PreparationMass SpectrometryPharmaceutical AnalysisEnvironmental ... The addition of dimethylethylamine to the sample diluent improved chromatography, and the lack of the amine in the modifier ... Dimethylethylamine was added to the sample diluent to improve the chromatography and to avoid further purification of the ...
Comprehensive and off-line supercritical fluid chromatography: reversed phase liquid chromatography for the analysis of complex ... "Comprehensive and Off-line Supercritical Fluid Chromatography: Reversed Phase Liquid Chromatography for the Analysis of Complex ... "Comprehensive and Off-line Supercritical Fluid Chromatography: Reversed Phase Liquid Chromatography for the Analysis of Complex ... Comprehensive and off-line supercritical fluid chromatography: reversed phase liquid chromatography for the analysis of complex ...
Supercritical Fluid Chromatography and Extraction (SFC/E). PACS Course Number 270. 9 AM to 5 PM. Larry Taylor, Ph.D. is the ... Download Printable Registration Form for Supercritical Fluid Chromatography and Extraction (SFC/E) ... Supercritical Fluid Chromatography and Extraction (SFC/E). Course Instructor: Larry Taylor, Ph.D. under the auspices of PACS. ... Supercritical Fluid Extraction and how it compliments SFC. Many SFC/SFE applications will be presented. Relationship of SFC to ...
Packed-column supercritical fluid chromatography (pSFC) with detection using atmospheric pressure chemical ionisation (APCI) ... The many faces of packed column supercritical fluid chromatography--a critical review.. *Eric Lesellier, Caroline West ... Packed-column supercritical fluid chromatography (pSFC) with detection using atmospheric pressure chemical ionisation (APCI) ... Identification and analysis of polymer additives using packed-column supercritical fluid chromatography with APCI mass ...
... and chemical characteristics of supercritical fluids have prompted the development of supercritical fluid chromatography (SFC) ... The use of polar modified fluids has been facilitated by advances in understanding of supercritical fluid phase behavior. Fluid ... and chemical characteristics of supercritical fluids have prompted the development of supercritical fluid chromatography (SFC) ... Kalinoski, H. T., Udseth, H. R., Chess, E. K., & Smith, R. D. (1987). Capillary supercritical fluid chromatography-mass ...
  • SFC is not accepted by Pharmacopeia committees for the analysis of drugs and medical forms to the same extent as Gas Chromatography, High-Performance Liquid Chromatography or even Thin Layer Chromatography. (scirp.org)
  • The technique used to pack these columns has been developed from a similar technology, which have been used for packing of columns, achieving very good separations, for both supercritical fluid chromatography (SFC) and high performance liquid chromatography (HPLC). (uio.no)
  • All lipid fractions were analyzed using thin-layer chromatography and high-performance lipid chromatography. (umn.edu)
  • In this report, supercritical fluid chromatography replaces HPLC as the desalting/separation technique prior to mass analysis, providing a dramatic reduction in back-exchange compared to the fast, cold HPLC methods. (utmb.edu)
  • Effects of organic modifier and temperature on the enantiomeric separation of several azole drugs using supercritical fluid chromatography and the Chiralpak AD column. (semanticscholar.org)
  • Enantiomeric separation of several antimycotic azole drugs using supercritical fluid chromatography. (semanticscholar.org)
  • article{Toribio2014EffectsOO, title={Effects of organic modifier and temperature on the enantiomeric separation of several azole drugs using supercritical fluid chromatography and the Chiralpak AD column. (semanticscholar.org)
  • Chiral separations in normal-phase liquid chromatography: Enantioselectivity of recently commercialized polysaccharide-based selectors. (semanticscholar.org)
  • The supercritical fluid chromatographic separations were conducted by a Lee Scientific SFC, Model $\beta$501 (Salt Lake City, UT) and a capillary column (17 m x 50 $\mu$m i.d.) with a stationary phase of 25% cyano propyl polymethyl siloxane at 80$\sp\prime$C. The Roquefort cheese samples contained more of the fatty acids in greater amounts than the Blue cheese. (illinois.edu)
  • François I, Dos Santos Pereira A, Sandra P. Comprehensive and off-line supercritical fluid chromatography: reversed phase liquid chromatography for the analysis of complex triglyceride profiles. (ugent.be)
  • International Journal of Analytical Mass Spectrometry and Chromatography , 2 , 15-24. (scirp.org)
  • Students will perform further analyses of the lipids for fatty acids and for potential environmental contaminants such as polychlorinated biphenyls, chlorinated pesticides, Dioxin and DDT using gas chromatography/mass spectrometry or flame ionization detector. (iated.org)
  • Reversed-phase screening strategies for liquid chromatography on polysaccharide-derived chiral stationary phases. (semanticscholar.org)
  • Effects of mobile phase composition and temperature on the supercritical fluid chromatography enantioseparation of chiral fluoro-oxoindole-type compounds with chlorinated polysaccharide stationary phases. (semanticscholar.org)
  • The extraction with supercritical CO$\sb2$ and a modifier of 5% methanol containing 1% acetic acid was done at 680 atm using a SFX 2-10 Isco Supercritical Fluid Extractor (Model 100DX, Lincoln, NE). (illinois.edu)
  • In order to effectively educate and train agriculture, food science and the more environmentally-conscious natural resources (fisheries/aquatic sciences/aquaculture) students, I will use the Spe-ed Supercritical Fluid Extractor (SFE) in our teaching laboratory. (iated.org)
  • Supercritical fluid chromatography for analysis and purification in drug discovery. (semanticscholar.org)
  • In the first step, nonpolar lipids in WPPC were removed using neat supercritical carbon dioxide (S-CO 2 ) at 41.4 MPa and 60°C. In the second stage, the feasibility of using the polar solvent ethanol as a co-solvent to increase the solubility of S-CO 2 extraction solvent was explored. (umn.edu)
  • A qualitative gas chromatography (GC) analysis showed that the individual FAMEs extracted varied depending on the co-solvent (methanol or hexane) used with supercritical CO 2 . (tudublin.ie)
  • The advantages of supercritical CO , such as having dif- 2 fusivity like a gas and solvating power depending on temperature and pressure, are also valid for other fluids and modified fluids. (springer.com)
  • The effects of organic modifier and temperature on the enantioseparation of 10 triazoles and eight imidazoles, using supercritical fluid chromatography with the Chiralpak AD column, have been investigated in this work. (semanticscholar.org)
  • These depend on the pressure, temperature and composition of the fluid. (hallanalytical.com)
  • In addition, the density (and therefore the solvent power of the fluid) may be adjusted by varying both the pressure and the temperature, affording the opportunity of theoretically performing highly selective extractions. (hallanalytical.com)
  • Supercritical fluid chromatography for the enantioseparation of pharmaceuticals. (semanticscholar.org)
  • In addition, as the modifier enhances the solvating power of the fluid, it reduces the extraction selectivity as more matrix materials or non-target analytes are co-extracted. (hallanalytical.com)
  • A review on the use of packed capillary columns in gas chromatography (GC) is presented. (uio.no)
  • I will train students how to use supercritical fluid technology - an environmentally benign technology - to extract lipids from fish, plant tissue, soil, and sediments. (iated.org)
  • In this study, a novel 2-step supercritical fluid extraction (SFE) process was used to extract whey protein phospholipid concentrate (WPPC), a dairy co-product obtained during the manufacture of whey protein isolate, for PL enrichment. (umn.edu)
  • Due to the numerous parameters affecting the extraction efficiencies, SFE affords a high degree of selectivity and it is this reason that supercritical fluid extraction has a wide range of industrial-scale uses. (hallanalytical.com)
  • The use of supercritical fluids in analytical chemistry is still grow- ing. (springer.com)
  • Analytical Chemistry Chromatographie Chromatography Extraction Extraktion (Chem. (springer.com)
  • SFC is not accepted by Pharmacopeia committees for the analysis of drugs and medical forms to the same extent as Gas Chromatography, High-Performance Liquid Chromatography or even Thin Layer Chromatography. (scirp.org)
  • The present method allowed for fast and high-resolution separation of monoesters to tetra-esters within a shorter time (15 min) as compared to the conventional high-performance liquid chromatography. (go.jp)
  • Complementary ultra-high-performance liquid chromatography method was developed using Ascentis Express F5 core-shell stationary phase and isocratic elution with 75% acetonitrile/methanol (1:1) and 25% water. (springer.com)
  • Previous batches of this compound were purified by high performance liquid chromatography (HPLC) using an amine additive in the modifier, and the NMR data showed that the isolated stereoisomers contained the amine after dry-down. (chromatographyonline.com)
  • paper chromatography , gas chromatography , and what would become known as high-performance liquid chromatography . (wikipedia.org)
  • Pentafluorophenyl-bonded silica (PFP) phases employed in high-performance liquid chromatography (HPLC) often provide very different results depending on the column manufacturer. (usda.gov)
  • Different methods such as thin layer chromatography and high performance liquid chromatography coupled with ultraviolet, refractive index, flame ionization detector, and mass spectrometry (MS) detection have long been used in the study of phospholipids. (vt.edu)
  • Supercritical fluid extraction-high performance liquid chromatography: on-line and off-line strategies. (booktopia.com.au)
  • The separation of isomeric compounds that are usually challenging for high.performance liquid chromatography (HPLC) can be accomplished by SFC . (musc.edu)
  • Bioanalytical characterization of the resulting powders involved spectrophotometry, sodium dodecyl sulfate-polycrylamide gel electrophoresis, reverse-phase high performance liquid chromatography (RP-HPLC), and size exclusion chromatography. (diva-portal.org)
  • High-performance liquid chromatography (HPLC) and related techniques (M. Gazdag). (elsevier.com)
  • The vendors that responded to the survey with high performance liquid chromatography (HPLC) and ultrahigh-pressure liquid chromatography (UHPLC) columns are listed in Table I. The product range is highly varied from traditional reversed-phase columns using fully porous materials to columns designed for alternate separation technologies such as supercritical fluid chromatography (SFC). (chromatographyonline.com)
  • High-pressure liquid chromatography, also called high performance liquid chromatography (HPLC), is now widely used in industry. (encyclopedia.com)
  • A high performance liquid chromatography (HPLC) system with ultraviolet detection was calibrated using 2 nanograms (ng), 4ng, and 8ng of aflatoxin-B1. (cdc.gov)
  • GONÇALVES C, CARVALHO JJ, AZENHA MA and ALPENDURA MF (2006) Optimisation of supercritical fluid extraction of pesticide residues in soil by means of central composite design and analysis by gas chromatography-tandem mass spectrometry. (scielo.org.za)
  • Supercritical fluid chromatography/tandem mass spectrometry (SFC/MS/MS) with methylation was used for the simultaneous profiling of diverse polar lipids in a mixture. (elsevier.com)
  • Waters Corp.'s new Acquity TQD puts the power of Ultra Performance Liquid Chromatography/Tandem Mass Spectrometry (UPLC/MS/MS) into the hands of chromatographers. (pharmamanufacturing.com)
  • Quantitative analysis of vitamin D and its main metabolites in human milk by supercritical fluid chromatography coupled to tandem mass spectrometry. (bvsalud.org)
  • Final extracts are derivatized with 4-phenyl-1,2,4-triazoline-3,5-dione and vitamin D derivatives analyzed by supercritical fluid chromatography hyphenated to tandem mass spectrometry with atmospheric pressure chemical ionization. (bvsalud.org)
  • Since the introduction of Liquid Chromatography-Tandem Mass Spectrometry (LC/MS/MS) into the clinical research laboratory over a decade ago, it has widely become accepted as the technique of choice for specific and accurate quantitation of many clinically relevant molecules in complex biological matrices. (separationsnow.com)
  • Key players in the European Super Critical Fluid Chromatography Reagents Market are Agilent Technologies, GE Healthcare, Helena Laboratories, Phenomenex, Inc., Thermo Fischer Scientific, W. R. Grace & Co., Waters Corporation & others. (prweb.com)
  • The super critical fluid chromatography reagents market in Europe was valued at $46.0 million in 2013, and is estimated to grow to $75.4 million by 2018, at a CAGR of 10.4% from 2013 to 2018. (prweb.com)
  • Super Critical Fluid Chromatography Reagents-North America can be segmented by Companies, Applications, Products, Processes, MacroIndicators and Endusers. (prweb.com)
  • Companies of Super Critical Fluid Chromatography Reagents-North America are Agilent Technologies, Phenomenex, Inc., GE Healthcare, W.R. Grace & Co., Helena Laboratories, Thermo Fisher Scientific, Waters Corporation and Other Companies. (prweb.com)
  • Applications of Super Critical Fluid Chromatography Reagents-North America are Analytical Chromatography Reagents and Preparative Chromatography Reagents. (prweb.com)
  • Products of Super Critical Fluid Chromatography Reagents-North America are Column Chromatography Reagents and Planar Chromatography Reagents. (prweb.com)
  • Processes of Super Critical Fluid Chromatography Reagents. (prweb.com)
  • The use of supercritical fluids in analytical chemistry is still grow- ing. (springer.com)
  • Analytical Chemistry Chromatographie Chromatography Extraction Extraktion (Chem. (springer.com)
  • Supercritical Fluid Chromatography (SFC) received an uneasy welcome, mainly because of the lack of commercially available analytical instruments. (scirp.org)
  • International Journal of Analytical Mass Spectrometry and Chromatography , 2 , 15-24. (scirp.org)
  • Chromatography may be preparative or analytical. (wikipedia.org)
  • Analytical chromatography is done normally with smaller amounts of material and is for establishing the presence or measuring the relative proportions of analytes in a mixture. (wikipedia.org)
  • Analytical chromatography is used to determine the existence and possibly also the concentration of analyte(s) in a sample . (wikipedia.org)
  • Thar Technologies, Inc., provider of supercritical fluid chromatography (SFC) systems spanning from analytical to preparative to process scale, announced that it opened the European headquarters of its SFC division in Berlin. (chemeurope.com)
  • PerkinElmer Life and Analytical Sciences, a global leader in application-focused measurement and analysis solutions, today at PITTCON® 2008, Booth #2555, announced the introduction of the Series 225 LC Autosampler to enable customers to meet the demanding needs for automation, quantitation and throughput in analyses using liquid chromatography (LC). (environmental-expert.com)
  • Supercritical fluid chromatography represents another, major analytical application. (booktopia.com.au)
  • This book discusses the recent developments which will lead to the routine use of supercritical fluid in analytical extensive chemistry. (booktopia.com.au)
  • Introduction to supercritical fluid extraction in analytical science. (booktopia.com.au)
  • Table 7-1 lists the applicable analytical methods for determining diazinon and its metabolites in biological fluids and tissues. (cdc.gov)
  • The book examines nearly all capillary chromatography approaches, combined with a variety of MS forms, giving readers a wide and detailed view on current-day analytical strategies and applications. (elsevier.com)
  • Junior scientists conducting research on mono-dimensional chromatography-MS fundamental relationships and experienced analytical chemists working in conventional capillary chromatography and classical multidimensional chromatography will find this an ideal application-based reference on the hyphenations of these domains. (elsevier.com)
  • The operator uses software to set mobile phase flow rate, co-solvent composition, system back pressure and column oven temperature which must exceed 40 °C for supercritical conditions to be achieved with CO2. (wikipedia.org)
  • Large volumes of solvents like methanol can limit the mass capacity of the column due to strong solvent effects that can distort the chromatography. (waters.com)
  • Major advantages of extracting metal species using supercritical CO 2 include minimization of waste solvent generation and direct removal of analytes from solid samples. (scribd.com)
  • nterest in supercritical fluid chromatography (SFC) applications is growing due to its ability to reduce analysis times, organic solvent consumption and waste production. (jascoinc.com)
  • Polar organic solvent chromatography. (semanticscholar.org)
  • Supercritical carbon dioxide (CO2) is well established for use as a processing solvent in polymer applications such as polymer modification, formation of polymer composites, polymer blending, microcellular foaming, particle production and polymerization. (scribd.com)
  • The nanotubes were further submitted to an extraction process using supercritical CO 2 as solvent. (scielo.br)
  • Carbon dioxide is a non-polar solvent once pressurised into a liquid or supercritical state. (york.ac.uk)
  • Stationary phases, solvent strength and buffers types will be addressed with respect to their unique impact on hydrophilic interaction chromatography, as well as advantages and disadvantages to the technique. (separationsnow.com)
  • Ionic liquids can form biphasic solvent systems with many organic solvents and water, and these solvent systems can be used in liquid-liquid separations and countercurrent chromatography. (springer.com)
  • Among the various extraction techniques, we explore the use of supercritical fluids (SC) as a solvent for the targeted extraction of terpenes from cannabinoids in Cannabis. (chromatographytoday.com)
  • Supercritical fluid chromatography (SFC) is a form of normal phase chromatography that uses a supercritical fluid such as carbon dioxide as the mobile phase. (wikipedia.org)
  • The mobile phase is composed primarily of supercritical carbon dioxide, but since CO2 on its own is too non-polar to effectively elute many analytes, cosolvents are added to modify the mobile phase polarity. (wikipedia.org)
  • The most common fluid applied in SFC and SFE is carbon dioxide. (springer.com)
  • Low viscosity carbon dioxide, the main component of the mobile phase in SFC, enables the use of higher flow rates than those generally used in liquid chromatography. (waters.com)
  • HU Q, PAN B, XU J, SHENG J and SHI Y (2007) Effects of supercritical carbon dioxide extraction conditions on yields and antioxidant activity of Chlorella pyrenoidosa extracts. (scielo.org.za)
  • Carbon dioxide at 400 atmospheres is a typical supercritical-fluid mobile phase. (britannica.com)
  • A system for measuring the solubility of various solid organic compounds in supercritical fluids such as methane or carbon dioxide for example, and for studying the equilibrium between the solid phase and the supercritical phase in a wide pressure and temperature range is disclosed. (freepatentsonline.com)
  • Insights into the Interfacial Process in Electroless Ni-P Coating on Supercritical CO2 Transport Pipeline as Relevant to Carbon Capture and Storage. (bioportfolio.com)
  • To reduce the amount of greenhouse gas emission and remedy the related environmental damages, the research on carbon capture and storage (CCS) is gaining momentum, so is the search for more effective way for corrosion control of pipeline steel used to transport impure supercritical (SC) CO2. (bioportfolio.com)
  • The study investigated the effect on hGH stability of adding isopropanol either as a cosolvent with the original aqueous protein solution (conventional process) or to the supercritical carbon dioxide before mixing with the aqueous protein solution (modified process). (diva-portal.org)
  • The solubility of chloramphenicol in pure supercritical fluid carbon dioxide (SF-CO2) has been determined using a continuously stirred supercritical solubility vessel (SSV) directly interfaced with online supercritical fluid chromatography (SFC) using a single valve interface. (x-mol.com)
  • We propose to use supercritical fluids (SCFs), specifically supercritical carbon dioxide (SCCO 2 ), as the reaction media. (epa.gov)
  • And we propose to carry them in supercritical carbon dioxide. (epa.gov)
  • In carbon storage activities, and in shale oil and gas extraction (SOGE) with carbon dioxide (CO 2 ) as stimulation fluid, CO 2 comes into contact with shale rock and its pore fluid. (mdpi.com)
  • The following methods of resolution of enantiomers are considered: supercritical fluid chromatography, capillary electrophoresis, thin-layer chromatography and high pressure liquid chromatography using phases and/or chiral additives. (worldwidescience.org)
  • Small-molecule reversed-phase columns, hydrophilic-interaction chromatography (HILIC) columns, and chiral columns continue to surface and are thus discussed separately. (chromatographyonline.com)
  • Coupled supercritical fluid extraction - capillary supercritical fluid chromatography. (booktopia.com.au)
  • For this purpose, two modern chromatographic approaches (ultra-high pressure liquid chromatography (UHPLC) and ultra-high performance supercritical fluid chromatography (UHPSFC)) were tested in combination with simple MS detector. (sigmaaldrich.com)
  • Nine tocopherol derivatives including four tocopherols, four tocotrienols, and one esterified form of α-tocopherol acetate were analyzed using ultra-high-performance supercritical fluid chromatography (UHPSFC) with diode array detection. (springer.com)
  • PIC-SFC is a leader in preparative supercritical fluid chromatography (SFC). (cannabizjournal.com)
  • In this series of papers, we aim to provide some insight into the retention and separation mechanisms occurring in enantioselective supercritical fluid chromatography (SFC). (usda.gov)
  • abstract = "The ring-opening polymerization of (R,S)-β-butyrolactone (BL) in bulk was analyzed with respect to the polymer structure of the resulting poly[(R,S)-3-hydroxybutanoate)] [P(3HB)] by isolation of the pure form using preparative supercritical CO2 fluid chromatography. (elsevier.com)
  • In particular, the relatively recently developed solution-enhanced dispersion by supercritical fluids (SEDS) technology has been employed in the preparation of particles/powders. (diva-portal.org)
  • The principal method used for the detection of diazinon or its metabolites in biological samples is gas chromatography (GC) using a flame photometric detector (FPD), a mass spectroscopy detector (MS), an electron capture detector (ECD), or a flame ionization detector (FID). (cdc.gov)
  • The properties of supercritical fluids will be surveyed, with emphasis on their chromatographic properties. (pacslabs.com)
  • While supercritical fluid chromatography (SFC) has been available for decades , very few labs have chosen to take advantage of its remarkable chromatographic properties . (musc.edu)
  • Supercritical fluid extraction and high performance liquid chromatographic determination of benzopyrans and phloroglucinol derivative in Hypericum polyanthemum. (nextbio.com)
  • Supercritical fluid chromatography (SFC) coupled with triple quadrupole mass spectrometry was applied to the profiling of sucrose fatty acid esters (SEs). (go.jp)
  • Chromatography is a physical method of separation that distributes components to separate between two phases, one stationary (stationary phase), the other (the mobile phase) moving in a definite direction. (wikipedia.org)
  • Its gas-like diffusivity and liquid-like density in the supercritical phase allow replacing conventional, often noxious, solvents with supercritical CO2. (scribd.com)
  • Supercritical fluids are neither gas nor liquid, but can be compressed gradually from low to high density and they are therefore interesting and important as tunable solvents and reaction media in the chemical process industry. (booktopia.com.au)
  • Separation and processing using supercritical solvents such as CO2 are currently on-line commercially in the food, essential oils and polymer industries. (booktopia.com.au)
  • The "Alternative Solvents" technology platform promotes the use of more sustainable solvents - supercritical / liquid CO 2 , bio-based solvents and solvents made from waste - as replacements for conventional organic solvents. (york.ac.uk)
  • The "Alternative Solvents" technology platform also operates a state of the art semi-preparative supercritical chromatography system. (york.ac.uk)
  • The objective of this study is to assess the potential benefits of using supercritical fluids as solvents in organic synthesis. (epa.gov)
  • ME Conferences is excited to announce the "10th International Conference on Mass Spectrometry and Chromatography" that will be held in October 08-09, 2018 at Dubai, UAE. (bioindustry.org)
  • This system runs extractions, reactions and analysis all in the supercritical phase. (york.ac.uk)
  • Resumen en inglés A bibliographic review on the raceme of propanolol chlorhydrate and its esters was made aimed at compiling the latest methods for its detection and the resolution of its racemic mix in order to provide information to pharmacists, synthesizer chemistry and other professionals connected with this topic. (worldwidescience.org)
  • The spectrofluorometry, the colorimetry, the thinlayer chromatography, and the high oressure liquid chromatography are reported as analysis techniques used for its detection. (worldwidescience.org)
  • Separation of coenzyme Q 10 in CPO and palm fibre oil was carried out using supercritical fluid chromatography with ultra violet detection. (thescipub.com)
  • Chapters cover key methods for sample introductions to the ion source, including direct flow, gas chromatography, liquid chromatography, and capillary electrophoresis. (springer.com)
  • Comparison of liquid chromatography and supercritical fluid chromatography coupled to compact single quadrupole mass spectrometer for targeted in vitro metabolism assay. (sigmaaldrich.com)
  • Designed with the same enabling technology platform as Waters ACQUITY Ultra-Performance Liquid Chromatography (UPLC) System, PATROL UPLC moves existing liquid chromatography (LC) analysis from off-line Quality Control (QC) laboratories directly to the manufacturing stream resulting in significant improvements in production efficiency with real-time analysis, reducing both process cycle times and assuring product quality. (pharmamanufacturing.com)
  • The second goal for this work was fractionation of phospholipids from lecithin (a by-product from soybean) by using supercritical fluid extraction (SFE) with methanol-modified CO2. (vt.edu)
  • An organic modifier (most commonly methanol) is often used to extend the solvating power of the mobile phase towards chromatography of more polar analytes. (ucalgary.ca)
  • Insights into chiral recognition mechanisms in supercritical fluid chromatography. (semanticscholar.org)
  • One approach of SFE of metals is by converting charged metal ions into neutral metal chelates using organic chelating agents dissolved in supercritical CO 2 [1-4]. (scribd.com)
  • Effects of organic modifier and temperature on the enantiomeric separation of several azole drugs using supercritical fluid chromatography and the Chiralpak AD column. (semanticscholar.org)
  • The effects of organic modifier and temperature on the enantioseparation of 10 triazoles and eight imidazoles, using supercritical fluid chromatography with the Chiralpak AD column, have been investigated in this work. (semanticscholar.org)
  • article{Toribio2014EffectsOO, title={Effects of organic modifier and temperature on the enantiomeric separation of several azole drugs using supercritical fluid chromatography and the Chiralpak AD column. (semanticscholar.org)
  • 1988. Standard method for measuring volatile organic matter by aqueous-injection gas chromatography - method D 2908-87. (cdc.gov)
  • Our objective in this project is to determine the feasibility of carrying out organic synthesis reactions in supercritical fluids. (epa.gov)
  • Our objective is to answer the fundamental question 'is it feasible and perhaps even more advantageous to carry organic synthesis reactions in supercritical fluids? (epa.gov)
  • New types of chromatography developed during the 1930s and 1940s made the technique useful for many separation processes . (wikipedia.org)
  • In practice, when the fraction of cosolvent is high, the mobile phase is not truly supercritical, but this terminology is used regardless. (wikipedia.org)
  • François I, Dos Santos Pereira A, Sandra P. Comprehensive and off-line supercritical fluid chromatography: reversed phase liquid chromatography for the analysis of complex triglyceride profiles. (ugent.be)
  • The study describes two different methods of extraction: solid-liquid extraction with acetone and supercritical fluid extraction. (worldwidescience.org)
  • Although supercritical fluid chromatography (SFC) is not a new technique, preparative SFC is becoming increasingly more popular with advances in instrumentation, software and chemistry. (waters.com)
  • Chromatography technique developed substantially as a result of the work of Archer John Porter Martin and Richard Laurence Millington Synge during the 1940s and 1950s, for which they won the 1952 Nobel Prize in Chemistry . (wikipedia.org)
  • Lee, CH & Holder, GD 1995, ' Use of Supercritical Fluid Chromatography for Obtaining Mass Transfer Coefficients in Fluid-Solid Systems at Supercritical Conditions ', Industrial and Engineering Chemistry Research , vol. 34, no. 3, pp. 906-914. (elsevier.com)
  • Osanai, Y , Toshima, K & Matsumura, S 2001, ' Lipase-catalyzed ring-opening polymerization of β-butyrolactone: End-group analysis of poly(3-hydroxybutanoate) using supercritical fluid chromatography ', Macromolecular Chemistry and Physics , vol. 202, no. 11, pp. 171-177. (elsevier.com)
  • Other notable contributions have been in the fields of supercritical fluids and related reverse micelle phenomena. (wikipedia.org)
  • The aim of the study was to investigate the feasibility of precipitating recombinant human growth hormone (hGH) from aqueous solutions using conventional and modified techniques of solution-enhanced dispersion (SEDS) by supercritical fluids. (diva-portal.org)
  • Planar chromatography (K. Ferenczi-Fodor, Z. Végh). (elsevier.com)
  • A somewhat different approach is the set of techniques known as "planar" or "thin layer" chromatography (TLC), in which no column is used at all. (encyclopedia.com)
  • This total system solution from Waters integrates and automates sample preparation capabilities, liquid chromatography instrumentation, a rich portfolio of column chemistries, process control communication interfaces, and a powerful chromatography data software application package. (pharmamanufacturing.com)
  • Other areas such as gas chromatography (GC), instrumentation, and sample preparation are covered elsewhere. (chromatographyonline.com)