Choroid Neoplasms
Choroid Plexus
Choroid
Choroid Plexus Neoplasms
Benign or malignant tumors which arise from the choroid plexus of the ventricles of the brain. Papillomas (see PAPILLOMA, CHOROID PLEXUS) and carcinomas are the most common histologic subtypes, and tend to seed throughout the ventricular and subarachnoid spaces. Clinical features include headaches, ataxia and alterations of consciousness, primarily resulting from associated HYDROCEPHALUS. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2072; J Neurosurg 1998 Mar;88(3):521-8)
Papilloma, Choroid Plexus
A usually benign neoplasm that arises from the cuboidal epithelium of the choroid plexus and takes the form of an enlarged CHOROID PLEXUS, which may be associated with oversecretion of CSF. The tumor usually presents in the first decade of life with signs of increased intracranial pressure including HEADACHES; ATAXIA; DIPLOPIA; and alterations of mental status. In children it is most common in the lateral ventricles and in adults it tends to arise in the fourth ventricle. Malignant transformation to choroid plexus carcinomas may rarely occur. (Adams et al., Principles of Neurology, 6th ed, p667; DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2072)
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Neoplasms
Neoplasms, Cystic, Mucinous, and Serous
Choroid Diseases
Cerebral Ventricle Neoplasms
Neoplasms located in the brain ventricles, including the two lateral, the third, and the fourth ventricle. Ventricular tumors may be primary (e.g., CHOROID PLEXUS NEOPLASMS and GLIOMA, SUBEPENDYMAL), metastasize from distant organs, or occur as extensions of locally invasive tumors from adjacent brain structures.
Neoplasms, Multiple Primary
Cerebrospinal Fluid
Uvea
Neoplasms, Second Primary
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
Immunohistochemistry
Ependyma
Adenocarcinoma, Mucinous
Pigment Epithelium of Eye
Myeloproliferative Disorders
Sclera
The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)
Gyrate Atrophy
Cystadenoma
Neoplasms, Connective and Soft Tissue
Neoplasms, Plasma Cell
Ornithine-Oxo-Acid Transaminase
Cysts
Eye
Ciliary Body
Cystadenoma, Mucinous
Ovarian Neoplasms
Meninges
Retina
The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.
Gastrointestinal Neoplasms
Carcinoma, Pancreatic Ductal
Neoplasms, Experimental
Neoplasms, Vascular Tissue
Lymphoma, T-Cell, Peripheral
A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. They include a broad spectrum of lymphocyte morphology, but in all instances express T-cell markers admixed with epithelioid histiocytes, plasma cells, and eosinophils. Although markedly similar to large-cell immunoblastic lymphoma (LYMPHOMA, LARGE-CELL, IMMUNOBLASTIC), this group's unique features warrant separate treatment.
International Classification of Diseases
A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (From ICD-10, p1). The Clinical Modifications, produced by the UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S.
Lymphoma, T-Cell
Dermoid Cyst
Cerebellar Ataxia
Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
Brachial Plexus
The large network of nerve fibers which distributes the innervation of the upper extremity. The brachial plexus extends from the neck into the axilla. In humans, the nerves of the plexus usually originate from the lower cervical and the first thoracic spinal cord segments (C5-C8 and T1), but variations are not uncommon.
Ependymoma
Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)
Ultrasonic characterisation of malignant melanoma of choroid. (1/324)
An in-vitro study of wave spectral analysis in 8 enucleated eyes was conducted in order to differentiate histological subtypes of malignant melanoma. To obtain the backscattering coefficient for the tissues, we used a broadband focussed transducer with a frequency range of 7-12 MHz and a centre frequency of 10 MHz. Experimental measurement of backscattering coefficient and attenuation coefficient at various frequencies was done by substitution techniques. The backscattering coefficient, scatterer size, and root mean square velocity fluctuation were derived by the numerical method, while the attenuation coefficient at 1 MHz was derived from attenuation coefficient at different frequencies. This study revealed that backscattering coefficient and attenuation coefficient, over a frequency range of 7-12 MHz, show an increase in the spindle cell type compared to the mixed cell type of malignant melanoma. Particularly, the scatterer size was significantly higher in the spindle cell group (p = 0.013) in contrast to the mixed cell type. Spindle cells have uniform and compact histological pattern which contributes to an increase in scatterer size and root mean square velocity fluctuation. The ultrasonically obtained parameters have been shown to have a good correlation with the histology of malignant melanoma. (+info)Radioactive phosphorus uptake testing of choroidal lesions. A report of two false-negative tests. (2/324)
Two false-negative results from 32P testing for histologically verified malignant melanomas of the choroid are reported. In the first case, a haemorrhagic choroidal detachment caused an increase in probe; additionally, the tumour was necrotic. Both factors are likely to have contributed to the false-negative result. A satisfactory explanation for the false-negative result in the second case was not determined, although it may have accurately reflected a period of minimal tumour activity, inasmuch as repeat 32P testing was strongly positive eight months later, when unequivocal evidence of tumour growth was present. An alternative explanation is that the orally administered 32P was incompletely absorbed. Since 32P testing is frequently accompanied by significant manipulation both in the manoeuvre associated with tumour localization and in that associated with the actual radioactive counting, it would seem desirable to perform indicated enucleation immediately after completion of the 32P testing. While the properly performed 32P test remains a valuable diagnostic test for helping to establish the presence or absence of malignancies of the posterior globe, it is important to guard against the tendency to underestimate careful clinical evaluation. (+info)Combination chemotherapy for choroidal melanoma: ex vivo sensitivity to treosulfan with gemcitabine or cytosine arabinoside. (3/324)
Treatment of choroidal melanoma by chemotherapy is usually unsuccessful, with response rates of less than 1% reported for dacarbazine (DTIC)-containing regimens which show 20% or more response rates in skin melanoma. Recently, we reported the activity of several cytotoxic agents against primary choroidal melanoma in an ATP-based tumour chemosensitivity assay (ATP-TCA). In this study, we have used the same method to examine the sensitivity of choroidal melanoma to combinations suggested by our earlier study. Tumour material from 36 enucleated eyes was tested against a battery of single agents and combinations which showed some activity in the previous study. The combination of treosulfan with gemcitabine or cytosine arabinoside showed consistent activity in 70% and 86% of cases, respectively. Paclitaxel was also active, particularly in combination with treosulfan (47%) or mitoxantrone (33%). Addition of paclitaxel to the combination of treosulfan + cytosine analogue added little increased sensitivity. For treosulfan + cytosine arabinoside, further sequence and timing experiments showed that simultaneous administration gave the greatest suppression, with minor loss of inhibition if the cytosine analogue was given 24 h after the treosulfan. Administration of cytosine analogue 24 h before treosulfan produced considerably less inhibition at any concentration. While we have so far been unable to study metastatic tumour from choroidal melanoma patients, the combination of treosulfan with gemcitabine or cytosine arabinoside shows activity ex vivo against primary tumour tissue. Clinical trials are in progress. (+info)Differential expression of the retinoblastoma gene family members in choroidal melanoma: prognostic significance. (4/324)
We evaluated 55 samples of choroidal melanoma managed by enucleation. Knowing that the immunohistochemical expression of the retinoblastoma gene family members Rb/p105, p107, and pRb2/p130 was inversely correlated with the degree of malignancy in at least some histological types, we investigated the expression of these three proteins in choroidal melanoma. We focused on the relationship between patient survival and the immunohistochemical detection of the retinoblastoma proteins. No correlation with clinical outcome was found for Rb/p105 and p107. However, we found pRb2/p130 to be an independent prognostic factor correlating positively or directly with patient survival times and indirectly or inversely with the degree of malignancy. Demonstration of the prognostic value of the immunohistochemical expression of pRb2/p130 is of significance, even if additional studies are required to confirm these data and to compare the prognostic value of pRb2/p130 immunodetection to that of other recently proposed markers, such as p53. (+info)Alpha/beta- and gamma/delta TCR(+) lymphocyte infiltration in necrotising choroidal melanomas. (5/324)
AIM: To detect specific tumour infiltrating T cells (TIL) carrying antigen specific MHC-I restricted receptor genes on necrotising and non-necrotising malignant melanomas and to correlate the findings with clinical data. METHODS: alpha/beta- and gamma/delta- TIL were determined by immunohistochemical staining in melanomas of patients with known follow up of more than 10 years. An antigen retrieval method was used to determine variable genes delta1 and gamma1 on TCR(+) cells by an anti-TCR Vdelta1 and anti-CrgammaM1, and of Valpha and Vbeta TCR(+) by an anti-pan-TCR(+) alpha/beta antibody. RESULTS: Intratumoral TIL were present in 86 of 113 (76.1%) necrotising melanomas (NMM) v 21 of 100 (21%) in non-necrotising melanomas (MM); of these, Valpha/beta- TCR(+) cells were present in 52 of 74 (70.3%) TIL harbouring NMM v four of 21 (19%) MM; Vgamma1 in 29 of 74 (39.2%) NMM v two of 21 (10%) MM; and Vdelta1 in 39 of 74 (52.7%) NMM v three of 21 (14%) MM. Extratumoral lymphocytic infiltration was seen in 86 (76.1%) NMM including Valpha/beta TCR(+) cells in 10 (11.6%) cases, v five (5%) MM cases with no Valpha/beta TCR(+) cells detected. Vgamma1 and Vdelta1 TCR(+) cells were not found in extratumoral infiltrates. CONCLUSIONS: In NMM, the median survival was 69.3 (range 6-237) months, 19 of 74 patients (25.7%) survived 5 years, and mortality was associated with advanced stage (p<0.001), patient age (p<0.023), and extent of necrosis (p<0.048). Survival was increased with evidence of Vgamma1 and Vdelta1 TCR(+) cells (p<0.026). (+info)Microvascular density in predicting survival of patients with choroidal and ciliary body melanoma. (6/324)
PURPOSE: Although malignant uveal melanoma disseminates predominantly hematogenously because of the absence of intraocular lymphatics, consensus about prognostic impact of microvascular density (MVD) has not been reached. This study was undertaken to investigate whether MVD, microvascular patterns, or both determine prognosis of uveal melanoma. METHODS: A population-based retrospective cohort study of melanoma-specific and all-cause mortality of 167 consecutive patients who had an eye enucleated because of choroidal or ciliary body melanoma from 1972 through 1981 was conducted. MVD was determined by counting tumor vessels in a masked fashion from areas of highest vessel density after immunostaining for CD34 epitope, factor VIII-related antigen (FVIII-RAg), and alpha-smooth muscle actin (SMA). Kaplan-Meier and Cox regression analyses of survival were performed. The association between MVD and tumor size and location, cell type, and microvascular patterns was assessed. RESULTS: MVD could be determined from 134 of 167 melanomas (80%). Based on globally highest count obtained with antibodies to CD34, MVD ranged from 5 to 121 vessels/0.313 mm2 (median, 40) and its association with presence of microvascular loops and networks (P = 0.0006), epithelioid cells (P = 0.028), and largest basal tumor diameter (P = 0.0029) was statistically significant. The 10-year melanoma-specific mortality increased with MVD (0.09, 0.29, 0.59, and 0.64, according to quartiles; P < 0.0001), as did all-cause mortality (P = 0.0022). Equivalent results were obtained with immunostaining for FVIII-RAg, whereas MVD obtained with antibodies to SMA was not associated with prognosis. Cox regression showed a hazard ratio of 2.45 (95% CI, 1.43-4.18) for presence of epithelioid cells, 1.11 (95% CI, 1.03-1.20) for largest basal diameter, 1.23 (95% CI, 1.06-1.43) for square root-transformed MVD, and 1.51 (95% CI, 1.09-2.10) for presence of loops and networks, all of which independently contributed to prognosis. CONCLUSIONS: The findings support the theory that both MVD and microvascular patterns contribute independently to prognosis in uveal melanoma in addition to cell type and size of the tumor. (+info)Ocular arterial blood flow of choroidal melanoma eyes before and after stereotactic radiotherapy using Leksell gamma knife: 2 year follow up. (7/324)
AIMS: To evaluate the effect of high dose stereotactic radiotherapy on the ocular blood flow of patients with uveal melanoma. METHODS: Colour Doppler imaging (CDI) was used to measure blood flow velocity and vascular resistance in the ophthalmic, short posterior, and central retinal arteries of nine patients suffering from uveal melanoma. The measurements were taken before, 6 months, 1 year, and 2 years after stereotactic radiotherapy. Irradiation was performed with the Leksell gamma knife with the 59 (41-66.5) Gy total marginal dose divided in two equal fractions. CDI results were compared with age and sex matched healthy control eyes. RESULTS: At each time of measurement, blood flow velocity in the central retinal artery of the affected eyes was significantly reduced whereas vascular resistance was only increased at the 2 year follow up. Blood flow velocity and vascular resistance in the short posterior arteries of melanoma eyes were also only significantly altered at the 2 year follow up. Blood flow velocity and vascular resistance in the ophthalmic artery of melanoma eyes were not changed at all follow ups. CONCLUSIONS: In the melanoma eyes, blood flow velocity in the central retinal artery is reduced. High dose stereotactic radiotherapy with the Leksell gamma knife and a 59 (41-66.5) Gy total marginal dose in two fractions leads to a significant reduction of blood flow and a significant increase in resistance variables in the small ocular arteries within 2 years. (+info)Transpupillary thermotherapy as primary treatment for small choroidal melanomas. (8/324)
PURPOSE: To report short-term follow-up of eyes containing small choroidal melanomas that were treated with transpupillary thermotherapy (TTT). METHODS: Twenty eyes with suspected small choroidal melanomas were treated with TTT using infrared light delivered from the diode laser. RESULTS: The age of patients ranged from 26 to 82 years. In 14, there was documented growth of the melanoma prior to TTT. Tumor thicknesses ranged from less than 1 to 3.2 mm. Seven tumors were treated more than once. Follow-up ranged from 6 months to more than 3 years. Following treatment, tumor thicknesses decreased in all cases, usually within 2 months. Progressive atrophy of tumor mass and loss of pigmentation within the tumor continued beyond 1 year of follow-up in some eyes. Complications included field defects, vascular changes, and macular abnormalities. CONCLUSIONS: Transpupillary thermotherapy of small choroidal melanomas is usually followed by early tumor shrinkage but is complicated by dense scotomas, nerve fiber bundle defects, and occasionally macular abnormalities. Short-term follow-up suggests that TTT may arrest growth of selected small melanomas. (+info)
Malignant Choroidal Melanoma
Imagen de PET/CT de melanoma coroideo metastásico
Bilateral Choroidal Metastasis as Initial Presentation of Parotid Gland Adenoid Cystic Carcinoma | Abstract
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A Case Report of Choroidal Metastasis from Renal Cell Carcinoma during
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Regrowth of Dog Eye Tumor
Papillary tumors of the pineal region
The critical diagnosis of this neoplasm is often difficult because of its similarity with other primary or secondary papillary ... These tumors were tested immunohistochemically with a profile similar to that of a choroid plexus tumor; however, ... the tumors appeared to be less differentiated than a choroid plexus papilloma and more differentiated than a choroid plexus ... is a recently described neoplasm that has been formally recognized in the 2007 World Health Organization (WHO) "Classification ...
List of diseases (C)
Choriocarcinoma Chorioretinitis Chorioretinopathy dominant form microcephaly Choroid plexus cyst Choroid plexus neoplasms ... syndrome Collins-Sakati syndrome Coloboma chorioretinal cerebellar vermis aplasia Coloboma hair abnormality Coloboma of choroid ... Carrington syndrome Cartilage-hair hypoplasia Cartilage hair hypoplasia like syndrome Cartilaginous neoplasms Cartwright-Nelson ... hypoxia Cerebral malformations hypertrichosis claw hands Cerebral palsy Cerebral thrombosis Cerebral ventricle neoplasms ...
List of MeSH codes (C10)
... brain neoplasms MeSH C10.228.140.211.280 - cerebral ventricle neoplasms MeSH C10.228.140.211.280.300 - choroid plexus neoplasms ... brain neoplasms MeSH C10.551.240.250.200 - cerebral ventricle neoplasms MeSH C10.551.240.250.200.200 - choroid plexus neoplasms ... spinal cord neoplasms MeSH C10.551.240.750.200 - epidural neoplasms MeSH C10.551.360.500 - optic nerve neoplasms MeSH C10.551. ... spinal cord neoplasms MeSH C10.228.854.765.342 - epidural neoplasms MeSH C10.228.854.770 - spinal cord injuries MeSH C10.228. ...
Fundus photography
... and neoplasm of the choroid, cranial nerves, retinal or eyeball. In patients with diabetes mellitus, regular fundus screening ... as the dye passes through the retina and choroid. Sodium Fluorescein Angiography (abbreviated SFA, FA or FAG) is used for the ...
List of diseases (P)
... familial Pancreatic diseases Pancreatic islet cell neoplasm Pancreatic islet cell tumors Pancreatic lipomatosis duodenal ... Papilledema Papillon-Lefèvre syndrome Papillitis of the lingual papillae Papillitis of the optic nerve Papilloma of choroid ... et varioliformis acuta Pityriasis rubra pilaris Piussan-Lenaerts-Mathieu syndrome Placenta disorder Placenta neoplasm Placental ... retardation-hyperkeratosis Parapsoriasis Parasitophobia Parastremmatic dwarfism Parathyroid cancer Parathyroid neoplasm ...
Nervous tissue
Neoplasms (tumours) in nervous tissue include: Gliomas (glial cell tumors) Gliomatosis cerebri, Oligoastrocytoma, Choroid ...
List of MeSH codes (C11)
... iris neoplasms MeSH C11.941.375.385 - iritis MeSH C11.941.855 - uveal neoplasms MeSH C11.941.855.198 - choroid neoplasms MeSH ... uveal neoplasms MeSH C11.319.494.198 - choroid neoplasms MeSH C11.319.494.400 - iris neoplasms MeSH C11.338.133 - blepharitis ... choroid diseases MeSH C11.941.160.177 - choroid hemorrhage MeSH C11.941.160.238 - choroid neoplasms MeSH C11.941.160.244 - ... conjunctival neoplasms MeSH C11.319.421 - eyelid neoplasms MeSH C11.319.457 - orbital neoplasms MeSH C11.319.475 - retinal ...
Choroid plexus papilloma
Internationally tumors of the choroid plexus are rare, accounting for 0.4-0.6% of all intracranial neoplasms. It most commonly ... Choroid plexus papilloma, also known as papilloma of the choroid plexus, is a rare benign neuroepithelial intraventricular WHO ... Media related to Choroid plexus papilloma at Wikimedia Commons Choroid Plexus Papilloma MRI, CT, and pathology images from ... Micrograph of a choroid plexus papilloma. H&E stain. Plexuspapillom Detail Plexuspapillom Overview Choroid plexus papillomas ...
Eye neoplasm
These tumors can occur in the choroid, iris and ciliary body. The latter are sometimes called iris or ciliary body melanoma. ... Eye neoplasms can affect all parts of the eye, and can be a benign tumor or a malignant tumor (cancer). Eye cancers can be ... Iridectomy - Removal of the affected piece of the iris Choroidectomy - Removal of the choroid layer (the vascular tissue ...
Chromatin remodeling
Similar mutations are also present in other childhood cancers, such as choroid plexus carcinoma, medulloblastoma and in some ... several more subunits of the human SWI/SNF chromatin remodeling complex have been found mutated in a wide range of neoplasms. ...
Eye neoplasm
These tumors can occur in the choroid, iris and ciliary body. The latter are sometimes called iris or ciliary body melanoma. ... Eye neoplasms can affect all parts of the eye, and can be a benign tumor or a malignant tumor (cancer). Eye cancers can be ... Choroidectomy - Removal of the choroid layer (the vascular tissue sandwiched between the sclera and the retina) ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Eye_neoplasm&oldid=895356793" ...
Papilloma
Choroid Plexus Papilloma - Palmer, Cheryl Ann and Daniel Keith Harrison; EMedicine; Jun 5, 2008 ... Glandular and epithelial neoplasms (ICD-O 8010-8589). Epithelium. Papilloma/carcinoma. (8010-8139). *Small cell carcinoma ...
Cyst
Choroid plexus cyst (in the brain). *Colloid cyst (in the brain). *Cysticercal cyst - an infection due to the larval stage of ... Cystic neoplasmEdit. Examples of neoplastic cysts include: *Dermoid cyst. *Keratocystic odontogenic tumor ...
List of diseases (G)
... fibromatosis dominant Gingival fibromatosis facial dysmorphism Gingival fibrosis Gingivitis Gyrate atrophy of the choroid and ... neuroendocrine tumor Gastroenteritis Gastroesophageal reflux Gastrointestinal autonomic nerve tumor Gastrointestinal neoplasm ...
Li-Fraumeni syndrome
Erratum for "Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms"". Science. 259 ( ... a proband who is diagnosed with adrenocortical carcinoma or choroid plexus tumour, irrespective of family history ... 1990). "Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms". Science. 250 (4985): ... Li F.P.; Fraumeni J.F. (October 1969). "Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?". Ann. ...
Heterochromia iridum
Neoplasm - Melanomas can also be very lightly pigmented, and a lighter colored iris may be a rare manifestation of metastatic ... and angioma of the choroid, often with secondary glaucoma. Simple heterochromia - a rare condition characterized by the absence ... A stimulation of melanin synthesis within iris melanocytes has been postulated.[medical citation needed] Neoplasm - Nevi and ...
Endolymphatic sac tumor
Aug 1993). "Papillary neoplasms (Heffner's tumors) of the endolymphatic sac". Ann. Otol. Rhinol. Laryngol. 102 (8 pt 1): 648-51 ... choroid plexus papilloma, middle ear adenocarcinoma, and ceruminous adenoma. Wide excision is the treatment of choice, although ... An endolymphatic sac tumor (ELST) is a very uncommon papillary epithelial neoplasm arising within the endolymphatic sac or ...
Li-Fraumeni syndrome
Li F.P.; Fraumeni J.F. (October 1969). "Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?". Ann. ... choroid plexus tumor, or rhabdomyosarcoma of embryonal anaplastic subtype, at any age of onset, irrespective of family history ... Erratum for "Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms"". Science. 259 ( ... 1990). "Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms". Science. 250 (4985): ...
List of MeSH codes (C04)
... uveal neoplasms MeSH C04.588.364.978.223 - choroid neoplasms MeSH C04.588.364.978.400 - iris neoplasms MeSH C04.588.443.353 - ... brain neoplasms MeSH C04.588.614.250.195.205 - cerebral ventricle neoplasms MeSH C04.588.614.250.195.205.200 - choroid plexus ... choroid plexus MeSH C04.588.614.250.195.411 - infratentorial neoplasms MeSH C04.588.614.250.195.411.100 - brain stem neoplasms ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ...
Cerebritis
These circulating complexes have been found trapped in the highly vascular choroid plexus of SLE patients upon autopsy. True ... and cannot reliably be distinguished from neoplasms. Cerebritis usually occurs as a result of an underlying condition, which ...
Intracranial pressure
In cases of confirmed brain neoplasm, dexamethasone is given to decrease ICP. Although the exact mechanism is unknown, current ... or choroid plexus tumor.[citation needed] Idiopathic or unknown cause (idiopathic intracranial hypertension, a common cause in ...
Syndecan 1
... negatively regulates initial leukocyte recruitment to the brain across the choroid plexus in murine experimental autoimmune ... a plasma cell marker immunohistochemical profile in hematopoietic and nonhematopoietic neoplasms". American Journal of Clinical ...
List of MeSH codes (C23)
... neoplasm seeding MeSH C23.550.727.650.895 - neoplasms, unknown primary MeSH C23.550.727.655 - neoplasm recurrence, local MeSH ... choroid hemorrhage MeSH C23.550.414.756.550 - hyphema MeSH C23.550.414.756.775 - retinal hemorrhage MeSH C23.550.414.756.887 - ... neoplasm metastasis MeSH C23.550.727.650.560 - lymphatic metastasis MeSH C23.550.727.650.645 - neoplasm circulating cells MeSH ... C23.550.727.670 - neoplasm regression, spontaneous MeSH C23.550.727.700 - neoplasm, residual MeSH C23.550.737.500 - retrograde ...
Brain tumor
Anaplastic astrocytoma, Astrocytoma, Central neurocytoma, Choroid plexus carcinoma, Choroid plexus papilloma, Choroid plexus ... Neoplasms will often show as differently colored masses (also referred to as processes) in CT or MRI results. ... The skull bone structure can also be subject to a neoplasm that by its very nature reduces the volume of the intracranial ... "CNS and Miscellaneous Intracranial and Intraspinal Neoplasms" (PDF). SEER Pediatric Monograph. National Cancer Institute. pp. ...
WHO classification of tumours of the central nervous system
Choroid plexus tumours 1.5.1 Choroid plexus papilloma (ICD-O 9390/0, WHO grade I) 1.5.2 Atypical choroid plexus papilloma ( ICD ... 3.4 Other neoplasms related to the meninges 3.4.1 Haemangioblastoma (ICD-O 9161/1, WHO grade I) 4.1 Malignant Lymphomas (ICD-O ... 9390/1, WHO grade II) 1.5.3 Choroid plexus carcinoma (ICD-O 9390/3, WHO grade III) 1.6. Other neuroepithelial tumours 1.6.1 ...
Lhermitte-Duclos disease
Nervous tissue tumors/NS neoplasm/Neuroectodermal tumor (ICD-O 9350-9589) (C70-C72, D32-D33, 191-192/225) ... Choroid plexus. *Choroid plexus tumor *Choroid plexus papilloma. *Choroid plexus carcinoma. Multiple/unknown. *Oligoastrocytoma ...
Primary central nervous system lymphoma
Nervous tissue tumors/NS neoplasm/Neuroectodermal tumor (ICD-O 9350-9589) (C70-C72, D32-D33, 191-192/225) ... Choroid plexus. *Choroid plexus tumor *Choroid plexus papilloma. *Choroid plexus carcinoma. Multiple/unknown. *Oligoastrocytoma ...
Meningioma
The neoplasms currently referred to as meningiomas were referred to with a wide range of names in older medical literature, ... Choroid plexus. *Choroid plexus tumor *Choroid plexus papilloma. *Choroid plexus carcinoma. Multiple/unknown. *Oligoastrocytoma ... Nervous tissue tumors/NS neoplasm/Neuroectodermal tumor (ICD-O 9350-9589) (C70-C72, D32-D33, 191-192/225) ... Even if, by general rule, neoplasms of the nervous system (brain tumors) cannot metastasize into the body because of the blood- ...
Uveal melanoma
... is a cancer (melanoma) of the eye involving the iris, ciliary body, or choroid (collectively referred to as the ... Kumar, Vinay (2009). "Uvea: Neoplasms". Robbins and Cotran Pathologic Basis of Disease, Professional Edition (8th ed.). ... Benign melanocytic tumors of the choroid, such as choroidal freckles and nevi, are very common and pose no health risks, unless ...
Index of oncology articles
... choroid plexus tumor - CHPP - chronic granulocytic leukemia - chronic idiopathic myelofibrosis - chronic leukemia - chronic ... neoplasm - nephrotomogram - nephrotoxic - nephroureterectomy - nerve block - nerve grafting - nerve-sparing radical ... Hürthle cell neoplasm - hydrazine sulfate - hydromorphone - hydronephrosis - hydroureter - hydroxychloroquine - hydroxyurea - ...
神經母細胞瘤 - 维基百科,自由的百科
脈絡叢腫瘤(英语:Choroid plexus tumor) *脈絡叢乳頭狀瘤(英语:Choroid plexus papilloma) ... 腦垂腺(英语:Pituitary neoplasm). *垂體腺瘤(英语:Pituitary adenoma):泌乳素瘤(英语:Prolactinoma) ... 腫瘤:內分泌腺腫瘤(英语:Endocrine gland neoplasm
Brain tumor
Anaplastic astrocytoma, Astrocytoma, Central neurocytoma, Choroid plexus carcinoma, Choroid plexus papilloma, Choroid plexus ... The skull bone structure can also be subject to a neoplasm that by its very nature reduces the volume of the intracranial ... "CNS and Miscellaneous Intracranial and Intraspinal Neoplasms" (PDF). SEER Pediatric Monograph. National Cancer Institute. pp. ... More generally a neoplasm may cause release of metabolic end products (e.g., free radicals, altered electrolytes, ...
ICD-10 Chapter VI: Diseases of the nervous system
Neoplasms III D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism ...
International Classification of Diseases for Oncology
NOS M8000/6 Neoplasm, metastatic Neoplasm, metastatic Tumor, metastatic Tumor, secondary Tumor embolus M8000/9 Neoplasm, ... NOS M9390/1 Atypical choroid plexus papilloma M9390/3 Choroid plexus carcinoma Choroid plexus papilloma, anaplastic or ... benign M8000/1 Neoplasm, uncertain whether benign or malignant Neoplasm, NOS Tumor, NOS Unclassified tumor, uncertain whether ... M8130/1 Papillary transitional cell neoplasm of low malignant potential (C67._) Papillary urothelial neoplasm of low malignant ...
Marginal zone B-cell lymphoma
... the brains choroid plexus (3 cases), inside brain [[Ventricular system[ventricle]] (1 case), the cerebellopontine angle (2 ... "The 2016 revision of the World Health Organization classification of lymphoid neoplasms". Blood. 127 (20): 2375-90. doi:10.1182 ...
Pathology of Choroid Plexus Neoplasms: Overview, Etiology, Clinical Features
Choroid plexus tumors are graded based on the World Health Organization (WHO) classification scheme and include choroid plexus ... tumors derived from choroid plexus epithelium that are seen predominantly in children. ... Choroid plexus neoplasms are rare, intraventricular, primary central nervous system (CNS) ... encoded search term (Pathology of Choroid Plexus Neoplasms) and Pathology of Choroid Plexus Neoplasms ...
Choroid plexus neoplasms - definition of Choroid plexus neoplasms by The Free Dictionary
Choroid plexus neoplasms synonyms, Choroid plexus neoplasms pronunciation, Choroid plexus neoplasms translation, English ... dictionary definition of Choroid plexus neoplasms. n a multilobed vascular membrane, projecting into the cerebral ventricles, ... that secretes cerebrospinal fluid Noun 1. choroid plexus - a vascular plexus of... ... Related to Choroid plexus neoplasms: Choroid Plexus Carcinoma. choroid plexus. n (Anatomy) a multilobed vascular membrane, ...
ICD-9 Code 239.81 -Neoplasms of unspecified nature, retina and choroid- Codify by AAPC
... retina and choroid is a medical classification as listed by WHO under the range - NEOPLASMS OF ... ICD-9 code 239.81 for Neoplasms of unspecified nature, ... Neoplasms of unspecified nature, retina and choroid (239.81). ... ICD-9 code 239.81 for Neoplasms of unspecified nature, retina and choroid is a medical classification as listed by WHO under ... the range -NEOPLASMS OF UNSPECIFIED NATURE (239).. Introducing Codify by AAPC: The Next Level of SuperCoder. SuperCoder will ...
MedPix Case - Choroid Plexus Neoplasm, Papilloma, Carcinoma
Choroid Neoplasms
... On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a ... Choroid Neoplasms. Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually ... Ranked list of diseases related to "Choroid Neoplasms"Drugs, active principles and "Choroid Neoplasms"Medicinal plantsQuestions ...
Benign Neoplasm of Choroid | Peterson Health
If you believe you have been exposed to COVID-19 or are experiencing symptoms, please do NOT go to the Emergency Department, a health care facility/clinic or the health department to seek testing or treatment. You need to self-isolate and call your primary care physician. If you do not have a primary care physician, contact Peterson Urgent Care at (830)258-7669 and they will assist you ...
Treatment of Tumors of the Choroid Plexus Epithelium - Full Text View - ClinicalTrials.gov
Choroid Plexus Neoplasms. Cerebral Ventricle Neoplasms. Brain Neoplasms. Central Nervous System Neoplasms. Nervous System ... Neoplasms by Site. Neoplasms. Brain Diseases. Central Nervous System Diseases. Nervous System Diseases. Cyclophosphamide. ... Indication criteria: Atypical choroid plexus papilloma or anaplastic choroid plexus papilloma histology with either metastases ... Treatment of Tumors of the Choroid Plexus Epithelium. The safety and scientific validity of this study is the responsibility of ...
ICD-10 Code: C69.3 - Malignant neoplasm of choroid
Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma ...
Central Nervous System Neoplasms. Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. Neoplasms. Neoplasms, ... Neoplasms, Germ Cell and Embryonal. Neoplasms, Nerve Tissue. Neoplasms by Site. Nervous System Diseases. Cyclophosphamide. ... childhood choroid plexus tumor. childhood high grade glioma. newly diagnosed childhood ependymoma. ... Choroid plexus carcinoma. *High grade glioma (including anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic ...
Imaging in Choroid Plexus Papilloma: Overview, Radiography, Computed Tomography
... histologically benign intracranial neoplasm that is commonly located in the ventricular system. These tumors account for 0. ... Choroid plexus papilloma is a rare, slow-growing, ... Pathology of Choroid Plexus Neoplasms * Ventricles of the Brain ... Choroid plexus papilloma is a rare, slow-growing, histologically benign intracranial neoplasm that is commonly located in the ... Choroid Plexus Neoplasms: Toward a Distinction between Carcinoma and Papilloma Using Arterial Spin-Labeling. AJNR Am J ...
adult choroid plexus neoplasm 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Cerebral Ventricle Neoplasms / secondary. Choroid Plexus Neoplasms / pathology. Choroid Plexus Neoplasms / secondary. Fourth ... MeSH-major] Choroid Plexus Neoplasms / diagnosis. Choroid Plexus Neoplasms / pathology. Meningeal Neoplasms / diagnosis. ... MeSH-major] Choroid Plexus Neoplasms / pathology. Choroid Plexus Neoplasms / physiopathology. Glioma / pathology. Glioma / ... Meningeal Neoplasms / secondary. Neoplasm Seeding. Papilloma, Choroid Plexus / surgery. *[MeSH-minor] Adult. Biomarkers, Tumor ...
2021 ICD-10-CM Diagnosis Code D31.30: Benign neoplasm of unspecified choroid
Benign neoplasm of unspecified choroid. 2016 2017 2018 2019 2020 2021 Billable/Specific Code *D31.30 is a billable/specific ICD ... Benign neoplasm of eye and adnexa. 2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code Type 1 Excludes*benign neoplasm ... Malignant neoplasm of ectopic tissue. *Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ... Neoplasms. Note*Functional activity. *All neoplasms are classified in this chapter, whether they are functionally active or not ...
Compound Report Card
Compound Report Card
Choroid Plexus Neoplasms. D016545. EFO:0007206. choroid plexus cancer. 3. ClinicalTrials. Leukemia, Biphenotypic, Acute. ... Ovarian Neoplasms. D010051. EFO:0003893. ovarian neoplasm. 3. ClinicalTrials. ClinicalTrials. Pancreatic Neoplasms. D010190. ... Nasopharyngeal Neoplasms. D009303. EFO:0004252. nasopharyngeal neoplasm. 2. ClinicalTrials. Neoplasms. D009369. EFO:0000311. ... Urethral Neoplasms. D014523. EFO:0003846. urethral neoplasm. 3. ClinicalTrials. ClinicalTrials. Uterine Cervical Neoplasms. ...
Dr. Mica Bergman, MD - Los Angeles, CA - Ophthalmology | Healthgrades.com
Dr. Adam Stewart, MD - Burleson, TX - Ophthalmology | Healthgrades.com
Dr. Pat-Michael Palmiero, MD - Fishkill, NY - Ophthalmology | Healthgrades.com
c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism | SpringerLink
Choroid plexus tumours (CPTs) account for 2-5% of brain tumours in children. They can spread along the neuraxis and can recur ... Choroid plexus tumours (CPT) are intracranial neoplasms derived from the choroid plexus epithelium. They predominantly occur in ... choroid plexus; CPT-choroid plexus tumour; ACPP - atypical choroid plexus tumour; CPP - choroid plexus papilloma; NSPCs - ... We show here that c-MYC overexpression in the choroid plexus epithelium induces T-cell inflammation-dependent choroid plexus ...
Magnetic resonance imaging characteristics of posterior scleritis mimicking choroidal mass
Diffuse choroidal melanocytoma in a child. A lesion extending the spectrum of melanocytic hamartomas
A 10-year-old white boy presented with a diffuse pigmented lesion of the choroid of his right eye that had led to a partial ... Choroid Neoplasms / complications * Choroid Neoplasms / diagnosis * Choroid Neoplasms / pathology* * Choroid Neoplasms / ... A 10-year-old white boy presented with a diffuse pigmented lesion of the choroid of his right eye that had led to a partial ... Light microscopic examination of the enucleated globe demonstrated that the choroid was diffusely and massively thickened by ...
Choroid Plexus Tumors | SpringerLink
Choroid plexus tumors (CPT) are rare tumors of the neuroepithelial tissue of the brain that are most common in young children. ... Choroid plexus neoplasms: toward a distinction between carcinoma and papilloma using arterial spin-labeling. AJNR Am J ... Choroid plexus Choroid plexus papilloma Atypical choroid plexus papilloma Choroid plexus carcinoma Radiation therapy ... There are three histopathological classifications of choroid plexus tumors: choroid plexus papilloma (CPP), atypical choroid ...
Needed for Review Flashcards by August Sivak | Brainscape
Draft ICD-10-CM/PCS MS-DRGv28 Definitions Manual
Neoplasm of unspecified behavior of retina and choroid. D4989. Neoplasm of unspecified behavior of other specified sites. ... Personal history of malignant neoplasm of tongue. Z85818. Personal history of malignant neoplasm of other sites of lip, oral ... Personal history of malignant neoplasm of cervix uteri. Z8542. Personal history of malignant neoplasm of other parts of uterus ... Personal history of malignant neoplasm of larynx. Z8522. Personal history of malignant neoplasm of nasal cavities, middle ear, ...
Extended Ophthalmoscopy - Medical Clinical Policy Bulletins | Aetna
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SNRPE Gene - GeneCards | RUXE Protein | RUXE Antibody
Efficacy and Safety Study of Lomustine/Temozolomide Combination Therapy vs. Standard Therapy for Glioblastoma Patients
Phase I EGFR BATs in Newly Diagnosed Glioblastoma
A Boy With Worsening Esotropia - American Academy of Ophthalmology
2 Fuller C. Pathology of Choroid Plexus Neoplasms. Medscape. http://emedicine.medscape.com/article/1744050-overview#a1. ... as opposed to choroid plexus carcinomas (WHO grade III), which are malignant.2 Choroid plexus papillomas cause the choroid ... Choroid plexus papillomas develop from the ventricular choroid plexus, which produces the cerebrospinal fluid (CSF) in the ... A choroid plexus papilloma is usually treated with a total mass resection.2 These resections have a high success rate even in ...
GENE.00023 Gene Expression Profiling of Melanomas
Most uveal tract melanomas originate in the choroid. The ciliary body is less commonly a site of origin, and the iris is the ... in newer prognostic molecular techniques such as gene expression profiling to differentiate benign from malignant neoplasms, or ... According to the National Cancer Institute (NCI, 2015), melanoma of the uveal tract (iris, ciliary body, and choroid) is the ...
PapillomaCarcinomaTumorPapillomasCarcinomasEpendymomaMelanomaRetinaCiliaryDiagnosisDerived from the choroid plexus epitheliumEpitheliumMeningiomaIntracranial neoplasmHydrocephalusHyperplasia of the choroid plexusPatients with choroid plexus tumorsPediatricNeuroendocrineResected choroid plexus tumorsMetastaticEpithelialOLIGODENDROGLIOMACentral nervous sOccurThird ventricleAdultCommon intraventricularTumors are rareIntraventricular neoplasmsRare tumorsMetastasisIntraocular tumorsSecond neoplasms
Papilloma23
- Choroid plexus tumors are graded based on the World Health Organization (WHO) classification scheme and include choroid plexus papilloma (CPP) (WHO grade I) (see the following image), atypical choroid plexus papilloma (WHO grade II), and choroid plexus carcinoma (CPC) (WHO grade III). (medscape.com)
- This coronal T1-weighted magnetic resonance image (MRI) following contrast administration shows a homogeneously enhancing choroid plexus papilloma within the right lateral ventricle of a 1-year-old boy. (medscape.com)
- Choroid plexus papilloma is a rare, slow-growing, histologically benign intracranial neoplasm that is commonly located in the ventricular system. (medscape.com)
- There are three histopathological classifications of choroid plexus tumors: choroid plexus papilloma (CPP), atypical choroid plexus papilloma (ACP), and choroid plexus carcinoma (CPC). (springer.com)
- Variations of disseminated choroid plexus papilloma: 2 case reports and a review of the literature. (springer.com)
- Choroid plexus papilloma in a girl with hypomelanosis of Ito. (springer.com)
- Suprasellar seeding of a benign choroid plexus papilloma of the fourth ventricle with local recurrence. (springer.com)
- Choroid plexus neoplasms: toward a distinction between carcinoma and papilloma using arterial spin-labeling. (springer.com)
- A choroid plexus papilloma is usually treated with a total mass resection. (aao.org)
- PTPR have morphological features in common with a number of other papillary-like tumors that occur in the pineal region, including pineal parenchymal neoplasms, choroid plexus papilloma, papillary ependymoma, metastatic papillary carcinomas, papillary meningioma and germ cell tumors ( 5 , 7 ), which complicates the clinical diagnosis of PTPR. (spandidos-publications.com)
- 53 Choroid plexus papilloma (CPP) ia a non-cancerous (benign) tumor of the choroid plexus, a network of blood vessels in the brain which surrounds the ventricles and produces the fluid surrounding the brain and spinal cord (cerebrospinal fluid, or CSF). (malacards.org)
- Papilloma of Choroid Plexus, also known as choroid plexus papilloma , is related to choroid plexus cancer and atypical choroid plexus papilloma , and has symptoms including seizures , vomiting and headache . (malacards.org)
- An important gene associated with Papilloma of Choroid Plexus is TP53 (Tumor Protein P53), and among its related pathways/superpathways are MAPK signaling pathway and Cell cycle . (malacards.org)
- 75 Papilloma of choroid plexus: A benign tumor of neuroectodermal origin that generally occurs in childhood, but has also been reported in adults. (malacards.org)
- Less frequent tumors include choroid plexus carcinoma or papilloma before the age of 15, rhabdomyosarcoma before the age of 5, leukemia, Wilms tumor, malignant phyllodes tumor, colorectal and gastric cancers. (proteopedia.org)
- 260500 ]. Choroid plexus papilloma is a slow-growing benign tumor of the choroid plexus that often invades the leptomeninges. (proteopedia.org)
- [8] [7] Glial fibrillary acidic protein (GFAP) may be positive in up to 20% of cases of choroid plexus papilloma. (statpearls.com)
- Genetic analyses have reported germline mutations in the TP53 gene in some patients with choroid plexus papilloma. (statpearls.com)
- Syndromic associations of choroid plexus papilloma include Aicardi syndrome, hypomelanosis of Ito, and 9p duplication. (statpearls.com)
- Choroid plexus papilloma, also known as papilloma of the choroid plexus, is a rare benign neuroepithelial intraventricular WHO grade I lesion found in the choroid plexus. (wikipedia.org)
- Choroid plexus papilloma occurs in the lateral ventricles of children and in the fourth ventricle of adults. (wikipedia.org)
- The critical diagnosis of this neoplasm is often difficult because of its similarity with other primary or secondary papillary lesions of the pineal region, including parenchymal pineal tumors, papillary ependymoma, papillary meningioma, choroid plexus papilloma, and metastatic papillary carcinoma. (wikipedia.org)
- however, morphologically the tumors appeared to be less differentiated than a choroid plexus papilloma and more differentiated than a choroid plexus carcinoma. (wikipedia.org)
Carcinoma10
- Gross total resection improves overall survival in children with choroid plexus carcinoma. (springer.com)
- Eppinger MA, Berman CM, Halpern SL, Mazzola CA (2016) Prolonged Survival for Choroid Plexus Carcinoma with Oncocytic Changes: A Case Report. (omicsonline.org)
- Introduction: Choroid plexus carcinoma (CPC) is a rare central nervous system neoplasm derived from the choroid plexus epithelium. (omicsonline.org)
- Choroid plexus carcinoma s ( CPC ) are rare, malignant neoplasms that represent 20-30% of CPTs in children [ 5 ]. (omicsonline.org)
- Pathological and immunohistochemical studies of choroid plexus carcinoma of the dog. (thefreedictionary.com)
- Choroid plexus carcinoma (CPC) is a rare brain tumor that occurs most commonly in very young children and has a dismal prognosis despite intensive therapy. (aacrjournals.org)
- 3. Patients who have a past or current history of neoplasm other than the entry diagnosis, except for curatively treated non-melanoma skin cancer or carcinoma in situ of the cervix or other cancers treated for cure and with a disease-free survival longer than 5 years. (knowcancer.com)
- The exemptions are primary brain tumors, among which the typical intracranial teratoma was not diagnosed, whereas 2 cases of rarely encountered neoplasms were reported: craniopharyngioma and choroid plexus carcinoma. (medscimonit.com)
- For example, CNS atypical teratoid/rhabdoid tumor is often misclassified as medulloblastoma, primitive neuroectodermal tumor, or choroid plexus carcinoma ( 1 ). (aacrjournals.org)
- If it undergoes malignant transformation it is called a choroid plexus carcinoma. (proteopedia.org)
Tumor16
- Choroid plexus neoplasms can produce hydrocephalus and increased intracranial pressure by a number of mechanisms, including obstruction of normal cerebrospinal fluid (CSF) flow, overproduction of CSF by the tumor itself, local expansion of the ventricles, or spontaneous hemorrhage. (medscape.com)
- The most frequent route of choroid plexus tumor spread is via seeding of the CSF. (medscape.com)
- To improve choroid plexus tumor treatment through better understanding of the tumor biology and through increased knowledge about the benefit of specific treatment elements. (clinicaltrials.gov)
- To compare the survival times after cyclophosphamide based treatment with the survival times after carboplatin based treatment in choroid plexus tumor patients. (clinicaltrials.gov)
- Although choroid plexus papillomas are readily apparent on most nonenhanced studies, the omission of enhanced imaging from the imaging protocol may result in incorrect conclusions about the tumor type and extent. (medscape.com)
- In addition, misdiagnosis may result from an attempt to classify a choroid plexus tumor as benign or malignant solely on the basis of imaging characteristics. (medscape.com)
- Choroid plexus papillomas may have limited parenchymal invasion, which makes the distinction of the benign tumor from its malignant counterpart difficult. (medscape.com)
- Light microscopic examination of the enucleated globe demonstrated that the choroid was diffusely and massively thickened by polygonal, hyperpigmented tumor cells that were also present in compressed spindled forms between the lamellae of scleral collagen, in the scleral emissaries, on the surface of the eyeball, and in the distal optic nerve dura. (nih.gov)
- Choroid plexus tumor epidemiology and outcomes: implications for surgical and radiotherapeutic management. (springer.com)
- However, the frozen section indicated a choroid plexus tumor, which has a significantly better prognosis. (aao.org)
- Choroid Cancer, also known as malignant tumor of the choroid , is related to melanoma, uveal and pulmonary aspergilloma . (malacards.org)
- see neoplasm neoplasm or tumor, tissue composed of cells that grow in an abnormal way. (thefreedictionary.com)
- Brain Tumor News: Second neoplasms in pediatric patients with primary central nervous system tumors: the St. Jude Children`s Research Hospital experience. (virtualtrials.com)
- Eye neoplasms can affect all parts of the eye , and can be a benign tumor or a malignant tumor ( cancer ). (wikipedia.org)
- [2] Binding of the large T antigen with both p53 and pRb tumor suppressor proteins, forming complexes, has been demonstrated in humans harboring choroid plexus tumors. (statpearls.com)
- The tumor is neuroectodermal in origin and similar in structure to a normal choroid plexus. (wikipedia.org)
Papillomas29
- Irrespective of patient age, choroid plexus papillomas outnumber choroid plexus carcinomas by a 5:1 ratio. (medscape.com)
- Up to 90% of choroid plexus tumors in children are papillomas, and up to 70% of all choroid plexus papillomas occur in children younger than 2 years. (medscape.com)
- Although the vast majority of choroid plexus tumors are sporadic, hereditary factors appear to play a role in the development of some choroid plexus papillomas and carcinomas. (medscape.com)
- Seeding of the CSF may be seen even in benign choroid plexus papillomas, but leptomeningeal dissemination is much more common in choroid plexus carcinomas. (medscape.com)
- According to cellular differentiation, number of mitosis and local invasion, choroid plexus neoplasms can be classified as choroid plexus papillomas or carcinomas (KOESTNER et al. (thefreedictionary.com)
- in children (mean age, 5.2 yr), choroid plexus papillomas appear as large tumors and account for 1.5-6.4% of intracranial neoplasms. (medscape.com)
- Computed tomography (CT) scanning and magnetic resonance imaging (MRI) are the investigative procedures of choice in the evaluation of choroid plexus papillomas. (medscape.com)
- The advent of CT scanning has resulted in improvement in the detection and characterization of all intracranial masses, including choroid plexus papillomas. (medscape.com)
- Choroid plexus papillomas appear as well-marginated round or lobulated solid masses and are isoattenuating or hyperattenuating relative to normal brain parenchyma on nonenhanced scans. (medscape.com)
- Choroid plexus papillomas are strongly enhancing after the intravenous administration of contrast material. (medscape.com)
- In children, choroid plexus papillomas can be heterogeneous in appearance because of the accumulation of cerebrospinal fluid (CSF), blood, and blood products between the fronds and papillae. (medscape.com)
- In adults, most choroid plexus papillomas are heterogeneous secondary to cystic and/or calcific degeneration. (medscape.com)
- We show here that c-MYC overexpression in the choroid plexus epithelium induces T-cell inflammation-dependent choroid plexus papillomas in a mouse model. (springer.com)
- Malignant progression in choroid plexus papillomas. (springer.com)
- Choroid plexus papillomas develop from the ventricular choroid plexus, which produces the cerebrospinal fluid (CSF) in the brain. (aao.org)
- The World Health Organization (WHO) classifies choroid plexus tumors as ranging from more benign papillomas, referred to as WHO Grade I, to carcinomas, referred to as WHO Grade III. (aao.org)
- 2 Excluding rare cases, choroid plexus papillomas of WHO grade I and II are almost always benign, as opposed to choroid plexus carcinomas (WHO grade III), which are malignant. (aao.org)
- 2 Choroid plexus papillomas cause the choroid plexus to overproduce CSF, and they can block normal CSF circulation, which leads to hydrocephalus. (aao.org)
- Choroid plexus papillomas (CPP) are very rare and are commonly found in the lateral ventricles (LV) in children. (minervamedica.it)
- The majority of CPTs are benign choroid plexus papillomas, which exhibit excellent prognosis [ 7 ]. (omicsonline.org)
- A total of 39 consecutive patients with pathologically proven CPTs (31 choroid plexus papillomas [CPPs] and 8 choroid plexus carcinomas [CPCs]) were included in this series. (thejns.org)
- 57 Choroid plexus tumors are of neuroectodermal origin and range from benign choroid plexus papillomas (CPPs) to malignant choroid carcinomas (CPCs). (malacards.org)
- Although generally found within the ventricular system, choroid plexus papillomas can arise ectopically in the brain parenchyma or disseminate throughout the neuraxis. (malacards.org)
- The standard isoform of CD44 is preferentially expressed in atypical papillomas and carcinomas of the choroid plexus. (uzh.ch)
- Choroid plexus papillomas (CPPs) are rare central nervous system tumors. (statpearls.com)
- Choroid plexus papillomas are rare tumors of neuroectodermal origin. (statpearls.com)
- According to the 2016 World Health Organization classification, [6] choroid plexus tumors are classified as papillomas (grade I), atypical tumors (grade II) and carcinomas (grade III). (statpearls.com)
- Choroid plexus papillomas have less than two mitotic figures per 10 high power fields, atypical ones have two to five per 10 high power fields, and carcinomas have greater than five mitotic figures per 10 high power fields. (statpearls.com)
- The relationship is reversed for choroid plexus papillomas. (wikipedia.org)
Carcinomas5
- Choroid plexus carcinomas are also far more common in the pediatric population, with approximately 80% of choroid plexus carcinomas occurring in children. (medscape.com)
- Choroid plexus carcinomas occasionally arise in association with hereditary cancer predisposition syndromes, including the Li-Fraumeni and rhabdoid predisposition syndromes, with germline mutations of TP53 and hSNF5/INI1/SMARCB1, respectively. (medscape.com)
- Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis. (springer.com)
- Typical choroid plexus carcinomas (CPCs) show variable morphology with a syncytial or solid arrangement. (thefreedictionary.com)
- CONCLUSIONS: In TySV40 transgenic mice, intraocular tumors develop that arise at the choroid-RPE interface, and they display morphologic and ultrastructural features consistent with RPE carcinomas. (arvojournals.org)
Ependymoma1
- As a group, gliomas are the most common primary central nervous system (CNS) neoplasms in both adult and pediatric populations, whereas infiltrative gliomas, in particular glioblastoma, make up the bulk of adult glial tumors, pilocytic astrocytoma, and ependymoma predominate in children. (hindawi.com)
Melanoma11
- Melanoma is a neoplasm known for its propensity for cardiac involvement. (biomedsearch.com)
- Other flat lesions in the choroid that have been confused with nevi and melanoma include hyperplasia of the retinal pigment epithelium, hamartomas of the retinal pigment epithelium, and hemorrhages within the retina, especially hemorrhages beneath the retinal pigment epithelium (as part of macular degeneration). (nih.gov)
- The choroid layer is the most likely site of melanoma in the eye. (medlineplus.gov)
- Iris nevi are composed of proliferated melanocytes and are associated with neurofibromatosis and malignant melanoma of the choroid and ciliary body. (curehunter.com)
- 2. Patients whose site of primary melanoma is not in the choroid(eye). (knowcancer.com)
- The study found that the pigmented neoplasms were ranked in the first place of ciliary body tumors, in which melanoma of ciliary body were majority. (arvojournals.org)
- To study the prevalence of multiple neoplasms in patients affected by uveal melanoma in Spain and to relate these with survival. (isciii.es)
- We carried out a longitudinal prospective study of the prevalence of multiple neoplasms in patients diagnosed to have a uveal melanoma during the years 1984-2005. (isciii.es)
- The data has been analysed for the following variables: age, sex, date of diagnosis, affected eye, origin and tumoral size, classification according to COMS (Collaborative Ocular Melanoma Study), time of follow-up, presence of other neoplasms, current clinical state, date and cause of death. (isciii.es)
- We did not find any statistically significant differences among the presentation age, sex or localization of the melanoma (ciliary body or choroid) and the presence or absence of a second neoplasm. (isciii.es)
- We have defined a relationship between metastasic uveal melanoma, and the development of a second neoplasm, which clearly indicates a need for increased systemic follow-up in such patients. (isciii.es)
Retina4
- ICD-9 code 239.81 for Neoplasms of unspecified nature, retina and choroid is a medical classification as listed by WHO under the range -NEOPLASMS OF UNSPECIFIED NATURE (239). (aapc.com)
- Benign tumors of the lid, conjunctiva, iris, and choroid are common, whereas those of the retina and cornea are rare. (nih.gov)
- Although the fluid usually resorbs and leakage stops within days to weeks, it has been suggested that photocoagulation itself somehow weakens the layer between the retina and choroid (Bruch membrane) and in some way may stimulate transformation to malignancy. (nih.gov)
- Iridectomy - Removal of the affected piece of the iris Choroidectomy - Removal of the choroid layer (the vascular tissue sandwiched between the sclera and the retina) Iridocyclectomy - Removal of the iris plus the ciliary body muscle. (wikipedia.org)
Ciliary6
- Even less common are melanocytomas originating in the choroid, ciliary body, or iris. (nih.gov)
- These tumors can occur in the choroid , iris and ciliary body . (wikipedia.org)
- By analyzing the histogenesis and classification, histopathologic characteristics, clinical feature and the key point of differential diagnosis of ciliary body neoplasms, the study provided the basis for clinical diagnosis and treatment. (arvojournals.org)
- Eighty-three specimens of ciliary body neoplasms on file (1959∼2005) were analyzed and studied for the characteristics of location, histogenesis, clinical presentation and histopathology. (arvojournals.org)
- 18 cases were melanocytoma, occupied 21.7% of the ciliary body neoplasms and 42.9% of the pigmented tumors. (arvojournals.org)
- By further recognizing the clinical features and histopathologic characteristics of ciliary body neoplasms, it may help clinical ophthalmologists to make correct diagnosis and proper treatment. (arvojournals.org)
Diagnosis4
- The radiologic finding of erosion of the skull base by this mass lesion may have contributed to its interpretation as a destructive neoplasm, with the differential diagnosis including chondrosarcoma, metastatic lesion, osteosarcoma, and meningioma. (thefreelibrary.com)
- However, the histology in this case ruled out a diagnosis of neoplasm. (thefreelibrary.com)
- Although BFH of the choroid is very rare, its benign nature and the availability of choroidal biopsy for tissue diagnosis make it important to include this as one of the differential diagnoses for amelanotic choroidal mass. (elsevier.com)
- The authors present the case of a child with partial trisomy 9p and delayed diagnosis of hydrocephalus with radiographic evidence of DVHCP who was successfully managed with ventriculoperitoneal shunt (VPS) placement, adjuvant bilateral endoscopic choroid plexus coagulation (CPC), and the novel application of anterior choroidal artery embolization. (thejns.org)
Derived from the choroid plexus epithelium1
- Choroid plexus tumours (CPT) are intracranial neoplasms derived from the choroid plexus epithelium. (springer.com)
Epithelium4
- Choroid plexus neoplasms are rare, intraventricular, primary central nervous system (CNS) tumors derived from choroid plexus epithelium that are seen predominantly in children. (medscape.com)
- It should be pointed out, however, that TTR is not entirely specific for choroid plexus neoplasms , since TTR immunoreactivity has been documented in several other neoplasms, retinal pigment epithelium, and hepatocytes. (thefreedictionary.com)
- WDPs have a consistent ocular phenotype of photophobia, hypopigmented adnexal structures, blue irides with a tan periphery and hypopigmented retinal pigment epithelium and choroid. (jove.com)
- PURPOSE: To characterize intraocular tumors that arise by in situ transformation in the choroid-retinal pigment epithelium (RPE) in transgenic mice bearing the SV40 oncogene under the control of the mouse tyrosinase promoter. (arvojournals.org)
Meningioma1
- Meningiomas Meningioma are the most common intracranial neoplasms. (vetstream.com)
Intracranial neoplasm2
- A broad spectrum of nonneoplastic conditions can radiologically and clinically mimic an intracranial neoplasm. (thefreelibrary.com)
- Hydrocephalus occurs when CSF production exceeds CSF absorption capacity (eg scarring of arachnoid villi or subarachnoid space secondary to haemorrhage or infection) or where there is an obstruction to CSF outflow (eg intracranial neoplasm). (brainfoundation.org.au)
Hydrocephalus2
- Diffuse villous hyperplasia of the choroid plexus (DVHCP) is a rare cause of communicating hydrocephalus. (thejns.org)
- We present a case of xanthogranuloma of the choroid plexus of the third ventricle, causing obstructive hydrocephalus of the lateral ventricles. (elsevier.com)
Hyperplasia of the choroid plexus1
- Duplication of 9P and hyperplasia of the choroid plexus: a pathologic, radiologic, and molecular cytogenetics study. (springer.com)
Patients with choroid plexus tumors2
- TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors. (springer.com)
- Young patients and patients with choroid plexus tumors appear to have an increased risk of SNs that is associated with genetic factors. (virtualtrials.com)
Pediatric8
- [ 2 , 3 ] In adults, they account for less than 1% of primary intracranial neoplasms, whereas choroid plexus tumors represent up to 5% of pediatric brain tumors, and up to 20% of those arising in children aged 1 year and younger. (medscape.com)
- In the pediatric population, the most common intradural extramedullary neoplasms are leptomeningeal metastases resulting from primary brain tumors whereas in adults non-CNS tumors are most commonly encountered. (radiopaedia.org)
- Radiologic-pathologic correlation of pediatric and adolescent spinal neoplasms: Part 2, Intradural extramedullary spinal neoplasms. (radiopaedia.org)
- BACKGROUND: Details on second neoplasms (SNs) following pediatric central nervous system (CNS) tumors are scant, because of the rarity of such SNs. (virtualtrials.com)
- Choroid plexus tumors (CPTs) are rare intracranial neoplasms that constitute approximately 2%-5% of all pediatric brain tumors. (thejns.org)
- Elzonris is a CD123-directed cytotoxin for the treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN) in adults and in pediatric patients 2 years and older. (drugs.com)
- Background: Congenital tumors form a unique group among pediatric neoplasms. (medscimonit.com)
- In the pediatric population, they form the third most common congenital brain tumors, after teratomas and gliomas, and account for 0.4 to 0.6% of all intracranial neoplasms. (statpearls.com)
Neuroendocrine2
Resected choroid plexus tumors1
- To compare response rates of incompletely resected choroid plexus tumors to two blocks of cyclophosphamide based treatment with the response rates after two blocks of carboplatin based treatment. (clinicaltrials.gov)
Metastatic1
- When we analysed the proportion of patients with metastatic disease (both alive and dead) who presented with a second neoplasm (40.9%), we found a statistically significant relationship between these variables (Chi-square test, p=0.004). (isciii.es)
Epithelial4
- Choroid plexus tumors (CPTs) are rare, intraventricular neoplasms that originate from the epithelial cells of the choroid plexus [ 1 - 4 ]. (omicsonline.org)
- MIB-1 immunoreactivity reveals different labelling in low-grade and in malignant epithelial neoplasms of the choroid plexus. (uzh.ch)
- Aquaporin 1 (AQP1) is found in the apical membrane of choroid plexus epithelial cells and is considered to have a role in CSF production. (brainfoundation.org.au)
- They may be created by epithelial cells of the choroid plexus. (wikipedia.org)
OLIGODENDROGLIOMA1
- Oligodendroglioma is an infiltrating glial neoplasm frequently seen in adults. (hindawi.com)
Central nervous s2
- Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). (bioportfolio.com)
- The new WHO classification introduces 7 changes in the grading of central nervous system neoplasms, ranging in significance from minor to major, in categories of anaplastic oligoastrocytomas, meningiomas, choroid plexus tumors, pineal parenchymal tumors, ganglioglioma, cerebellar liponeurocytoma, and hemangiopericytomas. (elsevier.com)
Occur2
- Primary choroid plexus tumors are rare and usually occur in early childhood. (proteopedia.org)
- Intracranial xanthogranulomas are rare benign tumors and occur most commonly as choroid plexus xanthogranulomas, which rarely become symptomatic. (elsevier.com)
Third ventricle1
- The third ventricle is the least common intraventricular location for choroid plexus neoplasms, irrespective of patient age. (medscape.com)
Adult2
- Clinical outcome of adult choroid plexus tumors: retrospective analysis of a single institute. (springer.com)
- The human IGF-II gene is maternally imprinted in all tissues except adult liver and the choroid plexus/leptomeninges of the central nervous system where IGF-II is biallelically expressed. (elsevier.com)
Common intraventricular1
- Neuroradiologically, intraventricular schwannomas cannot be differentiated with certainty from other, more common intraventricular neoplasms such as ependymal and choroid plexus tumors. (upmc.edu)
Tumors are rare1
- Malignant rhabdoid tumors are rare, highly aggressive neoplasms found most commonly in infants and young children. (aacrjournals.org)
Intraventricular neoplasms1
- Intraventricular neoplasms are uncommon, representing just 1-10% of all CNS tumors ( 1 - 4 ). (ajnr.org)
Rare tumors1
- Choroid plexus tumors (CPT) are rare tumors of the neuroepithelial tissue of the brain that are most common in young children. (springer.com)
Metastasis1
- The TySV40 transgenic murine tumors represent potentially useful tools for investigations into the biology and metastasis of intraocular neoplasms. (arvojournals.org)
Intraocular tumors2
- most common intraocular tumors are malignant melanomas of the choroid . (lookfordiagnosis.com)
- The most common intraocular tumors are in fact, malignant melanomas of the choroid which increase in frequency as we age. (utah.edu)
Second neoplasms1
- We have observed a percentage of second neoplasms similar to that described in other international studies. (isciii.es)