Choroid diseases. Medical search

Disorders of the choroid including hereditary choroidal diseases, neoplasms, and other abnormalities of the vascular layer of the uvea.

A villous structure of tangled masses of BLOOD VESSELS contained within the third, lateral, and fourth ventricles of the BRAIN. It regulates part of the production and composition of CEREBROSPINAL FLUID.

The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.

Benign or malignant tumors which arise from the choroid plexus of the ventricles of the brain. Papillomas (see PAPILLOMA, CHOROID PLEXUS) and carcinomas are the most common histologic subtypes, and tend to seed throughout the ventricular and subarachnoid spaces. Clinical features include headaches, ataxia and alterations of consciousness, primarily resulting from associated HYDROCEPHALUS. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2072; J Neurosurg 1998 Mar;88(3):521-8)

A usually benign neoplasm that arises from the cuboidal epithelium of the choroid plexus and takes the form of an enlarged CHOROID PLEXUS, which may be associated with oversecretion of CSF. The tumor usually presents in the first decade of life with signs of increased intracranial pressure including HEADACHES; ATAXIA; DIPLOPIA; and alterations of mental status. In children it is most common in the lateral ventricles and in adults it tends to arise in the fourth ventricle. Malignant transformation to choroid plexus carcinomas may rarely occur. (Adams et al., Principles of Neurology, 6th ed, p667; DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2072)

Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).

Neoplasms located in the brain ventricles, including the two lateral, the third, and the fourth ventricle. Ventricular tumors may be primary (e.g., CHOROID PLEXUS NEOPLASMS and GLIOMA, SUBEPENDYMAL), metastasize from distant organs, or occur as extensions of locally invasive tumors from adjacent brain structures.

A watery fluid that is continuously produced in the CHOROID PLEXUS and circulates around the surface of the BRAIN; SPINAL CORD; and in the CEREBRAL VENTRICLES.

The pigmented vascular coat of the eyeball, consisting of the CHOROID; CILIARY BODY; and IRIS, which are continuous with each other. (Cline et al., Dictionary of Visual Science, 4th ed)

A thin membrane that lines the CEREBRAL VENTRICLES and the central canal of the SPINAL CORD.

The layer of pigment-containing epithelial cells in the RETINA; the CILIARY BODY; and the IRIS in the eye.

The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)

Progressive, autosomal recessive, diffuse atrophy of the choroid, pigment epithelium, and sensory retina that begins in childhood.

Idiopathic central serous chorioretinopathy. (1/183)

Idiopathic central serous chorioretinopathy (ICSC) is usually seen in young males with Type A personality. Clinical evaluation of the macula with fundoscopy and biomicroscopy, coupled with fluorescein angiography establishes the diagnosis. Indocyanine green angiographic studies have reinformed that the basic pathology lies in choriocapillaries and retinal pigment epithelium. Most of the ICSC resolve completely in four months, and some of them could resolve early with direct photocoagulation of the leaking site. Oral steroids have no role, and could even cause an adverse reaction. (+info)

The pathogenesis of choroidal neovascularization in patients with age-related macular degeneration. (2/183)

Laser photocoagulation and several experimental treatments for choroidal neovascularization (CNV) in patients with age-related macular degeneration attempt to ablate the neovascularization, but do not address underlying angiogenic stimuli. As a result, recurrences are a major problem. Drug treatment to counter the growth of CNV would be a major advance, but its development is impeded by lack of knowledge concerning the stimuli and other molecular signals involved in the pathogenesis of CNV. Herein we explore clues that can be gleaned from clinical, epidemiological, pathological, and experimental data. These suggest that abnormalities of the extracellular matrix of retinal pigmented epithelial (RPE) cells may promote a pro-angiogenic RPE phenotype that contributes to the development of CNV. This provides a general hypothesis that can be tested, but it is also necessary to test hypotheses regarding the specific alterations in gene expression that contribute to CNV. Identification of alterations in gene expression will provide targets for rational design of drug treatment. (+info)

Autosomal dominant macular atrophy at 6q14 excludes CORD7 and MCDR1/PBCRA loci. (3/183)

PURPOSE: Localization of the gene responsible for autosomal dominant atrophic macular degeneration (adMD) in a large pedigree UM:H785. METHODS: Standard ophthalmologic examinations were performed. Microsatellite markers were used to map the disease gene by linkage and haplotype analyses. RESULTS: The macular degeneration in this family is characterized by progressive retinal pigment epithelial atrophy in the macula without apparent peripheral involvement by ophthalmoscopy or functional studies. Acuity loss progressed with age and generally was worse in the older affected individuals. The rod and cone function remained normal or nearly normal in all tested affected members up to 61 years of age. The phenotype in our family has characteristics similar to Stargardt-like macular degeneration with some differences. Haplotype analysis localized the disease gene in our adMD family to an 8-cM region at 6q14, which is within the 18-cM interval of STGD3 but excludes cone-rod dystrophy 7 (CORD7; centromeric) and North Carolina macular degeneration and progressive bifocal chorioretinal atrophy (MCDR1/PBCRA; telomeric). The mapping interval overlaps with that of recessive retinitis pigmentosa (RP25). CONCLUSIONS: These results implicate at least three genetically distinct loci for forms of macular degeneration that lie within a 30-cM interval on chromosome 6p11-6q16: CORD7, adMD, and MCDR1/PBCRA. Because the critical interval for the adMD family studied overlaps with STGD3 and RP25, these loci could be allelic. (+info)

Fluorescein angiographic features of choroidal insufficiency in anterior ischemic optic neuropathy. (4/183)

Anterior ischemic optic neuropathy(AION) is known to be caused by circulatory disturbance in the anterior optic nerve(AON). Because the AON shares blood supply from the paraoptic short posterior ciliary artery with peripapillary choroid, the authors investigated the angiographic evidences of combined choroidal insufficiency in patients with acute AION. Fundus fluorescein angiograms from 30 eyes from 28 patients with acute AION were enrolled in this study. The diagnosis of acute AION was based primarily on angiographic evidences of filling delay of optic nerve head and the various clinical features, such as decreased visual acuity, visual field defects, afferent pupillary defect, and optic disc swelling. Angiographic evidences of combined choroidal filling delay were as follows: 1) circular or localized filling delay of peripapillary choroid in 15 eyes (50%), 2) generalized filling delay of posterior pole in 11 eyes (36.7%), 3) filling delay of unilateral choroid divided by watershed zone in 5 eyes (16.7%), and 4) choriocapillary filling delay in 10 eyes (33.3%). In this study, various types of choroidal insufficiency in patients with AION were observed, which helped us to differentiate AION from the other various diseases of the anterior optic nerve. (+info)

Bullous variant of idiopathic central serous chorioretinopathy. (5/183)

BACKGROUND: Spontaneous bullous serous retinal detachment (RD) with subretinal exudation complicating idiopathic central serous chorioretinopathy (ICSC) is a rare and infrequently described clinical entity. Clinical observations are described on this variant form in 11 patients, the largest series reported to date. METHODS: 13 eyes of 11 Indian patients having this entity were followed up clinically and angiographically for 12-24 months (retrospective, longitudinal). None of the patients had any previous history of other diseases nor were they on any medications. Four eyes received laser treatment (group A); nine eyes were not treated (group B). RESULTS: All 11 patients were male, aged 23-49 years (median 37 years). The clinical and photographic records revealed subretinal exudation and inferior bullous serous RD complicating ICSC with evidence of large, single or multiple, leaking retinal pigment epithelial detachments (PEDs) in all the cases. In group A, resolution of serous RD occurred in 12 weeks (median) with a visual recovery of >/=20/30 in three out of four eyes while in group B resolution of serous retinal detachment was observed in 14 weeks (median) with eight out of nine eyes achieving a visual acuity of >/=20/30. Subretinal fibrosis developed in two eyes in group A and none of the eyes in group B. CONCLUSION: The disease is an exaggerated form of ICSC and can occur spontaneously without any history of corticosteroid therapy. Recognition of this atypical presentation is important to avoid inappropriate treatment. These observations suggest that with respect to the duration of the disease and the final visual outcome laser therapy offers no additional benefit over the natural course of this variant form of ICSC. (+info)

CT-revealed choroidal effusions as a sign of carotid cavernous fistula. (6/183)

Choroidal effusions may appear as subtle abnormalities on CT scans. Recognition of choroidal effusions, however, is critical because they may be an early sign of ocular pathologic abnormality. After detection, the various causes of choroidal effusions, such as carotid cavernous fistulas, ocular hypotony, tumors, and inflammatory conditions, should be considered. (+info)

Choroidal thickness changes during altered eye growth and refractive state in a primate. (7/183)

PURPOSE: In the chick, compensation for experimentally induced defocus involves changes in the thickness of the choroid. The choroid thickens in response to imposed myopic defocus and thins in response to imposed hyperopic defocus. This study was undertaken to determine whether similar choroidal changes occur in the primate eye with induced refractive errors. METHODS: Thirty-three common marmosets were used. Eyes in 26 monkeys served as untreated control eyes, and eyes in 7 received 3 weeks of monocular lid suture to induce changes in eye growth and refractive state. Refractive errors were measured using refractometry and retinoscopy, and axial ocular dimensions, including choroidal thickness, were measured using high-frequency A-scan ultrasonography. Eyes were measured before the lids were sutured and at frequent intervals after lid opening. RESULTS: In the marmoset, choroidal thickness ranges from 88 to 150 microm and increases significantly during the first year of life. Monocular lid suture initially results in short, hyperopic eyes that then become elongated and myopic. In these animals the choroids of both the experimental and the fellow control eyes also increase in thickness with age but additionally show interocular differences that vary significantly with the relative changes in vitreous chamber depth and refraction. In eyes that are shorter and more hyperopic than control eyes the choroids are thicker, and in eyes that are longer and more myopic than control eyes the choroids are thinner. CONCLUSIONS: In marmosets, the thickness of the choroid increases during postnatal eye growth. Superimposed on this developmental increase in choroidal thickness there are changes in thickness that are correlated with the induced changes in eye size. These changes are small (<50 microm) in comparison with those observed in the chick, contributing to less than a diopter change in refractive error. (+info)

Early treatment with cyclosporin in serpiginous choroidopathy maintains remission and good visual outcome. (8/183)

AIMS: To describe management and clinical outcomes of serpiginous choroidopathy treated primarily with cyclosporin at a tertiary uveitis referral centre METHODS: A case series of 14 eyes of seven patients with serpiginous choroidopathy with follow up ranging from 1.3 to 13 years is described. All patients had fundus lesions consistent with serpiginous choroidopathy, were investigated for systemic disease, had fluorescein angiography, and were treated with combined immunosuppressive therapy including cyclosporin. RESULTS: No patients suffered significant loss of acuity after starting systemic immunosuppression with cyclosporin as the primary agent. All but one patient achieved remission and were able to stop medications with no recurrences in the follow up period. Side effects from cyclosporin were well tolerated and there were no serious complications from immunosuppression. CONCLUSIONS: Cyclosporin is a safe and effective option with which to manage serpiginous choroidopathy. Significantly, adequate immunosuppression can result in clinical remission and cessation of therapy in some patients. (+info)

Über die Krankheiten der Choreida (1837) - On diseases of the choroid. Die Krankheiten des Höheren Alters und Ihre Heilung ( ... He was also the author of treatises on diseases of the eyes (1841) and Bright's disease (1844). Significant publications by ... The following year, he went to Paris to study Asiatic cholera, a disease that was then epidemic in the French capital. ... Canstatt's study of the disease, published in 1832, attracted the attention of the Belgian government, which commissioned him ...

https://en.wikipedia.org/wiki/Karl_Friedrich_Canstatt

PCV is an ocular disease characterised by abnormally shaped vessels in the choroid. It is described as an exudative maculopathy ... Polypoidal choroidal vasculopathy (PCV) is an eye disease primarily affecting the choroid. It may cause sudden blurring of ...

https://en.wikipedia.org/wiki/Polypoidal_choroidal_vasculopathy

Articles with short description, Short description is different from Wikidata, Eye diseases, Disorders of choroid and retina). ... it is leading some to believe that geographic atrophy is primarily an ischemic disease (disease due to decreased blood flow). ... As the disease progresses, vision-related quality-of-life declines markedly. While fluorescein angiography and optical ... Lindblad, AS; Lloyd, PC; Clemons, TE; Gensler, GR; Ferris FL, 3rd; Klein, ML; Armstrong, JR; Age-Related Eye Disease Study ...

https://en.wikipedia.org/wiki/Geographic_atrophy

Article on PRA Article on Cataracts (CS1 errors: generic name, Dog diseases, Disorders of choroid and retina). ... This is a disease with normal rod and cone cell development but late onset degeneration of the rod cells that progresses to the ... Samoyed - More severe disease than the Husky. Bullmastiff - Inherited as an autosomal dominant trait due to a mutation in the ... Absent a genetic test, animals of breeds susceptible to PRA can be cleared of the disease only by the passage of time-that is, ...

https://en.wikipedia.org/wiki/Progressive_retinal_atrophy

CEA is a congenital, inherited eye disease involving the retina, choroid, and sclera that sometimes affects border collies. In ... "Dog disease gets the bite". Science.unsw.edu.au. 2005. Archived from the original on 10 August 2007. Retrieved 12 August 2007. ... The mutation causing the form of the disease found in border collies was identified by Scott Melville in the laboratory of Dr ... Neuronal ceroid lipofuscinosis (NCL) is a rare but serious disease that is limited to show border collies. NCL results in ...

https://en.wikipedia.org/wiki/Border_Collie

Articles with short description, Short description matches Wikidata, Disorders of choroid and retina, Autoimmune diseases, ... The disease is poorly understood, but may be the result of cancer or cancer chemotherapy. The disease is an autoimmune ... AIR symptoms are numerous and shared by many other diseases. Diagnosis of AIR can be difficult due to the overlap of symptoms ... Autoimmune retinopathy (AIR) is a rare disease in which the patient's immune system attacks proteins in the retina, leading to ...

https://en.wikipedia.org/wiki/Autoimmune_retinopathy

It is assumed that a large part of the population has a thickened choroid without other signs of disease. This includes mainly ... especially in the deep choroid (the so-called Haller's layer). This results in increased pressure from the deep choroid against ... The disease mechanisms are not completely understood. All pachychoroid disorders of the macula show choroidal thickening and ... Pachychoroid disorders of the macula represent a group of diseases affecting the central part of the retina of the eye, the ...

https://en.wikipedia.org/wiki/Pachychoroid_disorders_of_the_macula

... also there is no systemic beneficial effect for cytomegalovirus organ disease. List of systemic diseases with ocular ... Disorders of choroid and retina). ... The Neglected Disease of the AIDS Pandemic". PLOS Medicine. 4 ( ... "Cytomegalovirus Disease , Adult and Adolescent OI Prevention and Treatment Guidelines , AIDSinfo". AIDSinfo. Archived from the ... "Inflammatory Retinal Diseases. Medical information , Patient". Patient. Retrieved 2016-03-16. V, Narendran; Kothari, Abhishek ( ...

https://en.wikipedia.org/wiki/Cytomegalovirus_retinitis

This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Rab (G- ...

https://en.wikipedia.org/wiki/Rab_escort_protein_1

OCT scanning can be used in detecting abnormalities of retina and choroid. To prevent retinal dysfunction and vision loss, ... Articles with short description, Short description is different from Wikidata, AC with 0 elements, Eye diseases, Disorders of ...

https://en.wikipedia.org/wiki/Hypotony_maculopathy

Weiter JJ, Roh S (December 1992). "Viral infections of the choroid and retina". Infectious Disease Clinics of North America. 6 ...

https://en.wikipedia.org/wiki/CII_protein

... (CEA) is a congenital, inherited, bilateral eye disease of dogs, which affects the retina, choroid, and ... The choroid is a collection of blood vessels supplying the retina. CEA can also cause retinal or scleral coloboma, coloboma of ... The choroid, especially lateral to the optic disc, is hypoplastic (underdeveloped). A coloboma, or hole, may form in or near ... The most common sign of CEA is the presence of an area of undeveloped choroid (appearing as a pale spot) lateral to the optic ...

https://en.wikipedia.org/wiki/Collie_eye_anomaly

As a young boy, he was diagnosed with Choroideremia, a congenital, X-linked, recessive disease of the retina and choroid, ...

https://en.wikipedia.org/wiki/John-Ross_Rizzo

This is clinically significant for diseases affecting choroidal blood supply. The macula responsible for central vision and the ... The choroid, also known as the choroidea or choroid coat, is a part of the uvea, the vascular layer of the eye, and contains ... Along with the ciliary body and iris, the choroid forms the uveal tract. The structure of the choroid is generally divided into ... The human choroid is thickest at the far extreme rear of the eye (at 0.2 mm), while in the outlying areas it narrows to 0.1 mm ...

https://en.wikipedia.org/wiki/Choroid

The disease is caused by an increase of melanocytes in the iris, choroid, and surrounding structures. Overproduction of pigment ... Articles with short description, Short description matches Wikidata, Dog diseases, Disorders of conjunctiva, Eye color). ...

https://en.wikipedia.org/wiki/Ocular_melanosis

... photoreceptor cell retinal ganglion cell macula capillary lamina of choroid (choriocapillaris) Eye diseases retinitis ... It addressed the progress of the disease choroideremia, or choroideraemia, in which a faulty gene, CHM, leads to a loss of REP1 ... 2016 Robot-Assisted Surgery Trial In the past, retinal diseases of the eye could be monitored to microscopic level - using ... Once the processes of the diseases are understood, new surgical technologies are furthering the options for a surgical solution ...

https://en.wikipedia.org/wiki/Robert_MacLaren

Rare diseases, Disorders of choroid and retina). ... BCD is a rare disease and appears to be more common in people ... Bietti's crystalline dystrophy at NIH's Office of Rare Diseases (Articles needing additional references from August 2020, All ... Bietti's crystalline dystrophy (BCD) is a rare autosomal recessive eye disease named after G. B. Bietti. ... choriocapillaries and choroid (the back layers of the eye). This tends to lead to progressive night blindness and visual field ...

https://en.wikipedia.org/wiki/Bietti's_crystalline_dystrophy

Eye diseases, Disorders of choroid and retina, Visual disturbances and blindness). ... All refer to the same disease. "Idiopathic macular telangiectasia type 3 is a rare, acquired, eye disease characterized by ... The two diseases may be distinguished by symptoms, clinical features, and pathogenesis. The natural history of macular ... The rarity of the disease however, makes it difficult to assess in a controlled randomized manner. A 2014 case study of a ...

https://en.wikipedia.org/wiki/Macular_telangiectasia

Rare diseases, Disorders of choroid and retina). ... The disease has strong association with the human leukocyte ... The disease affects typically middle-aged or elderly caucasians. HLA-A29 is less prevalent in Asia and no birdshot ... It causes severe, progressive inflammation of both the choroid and retina. Affected individuals are almost exclusively ... ERAP-HLA associations have also been reported in Ankylosing spondylitis and Behcet's disease, suggesting shared pathogenic ...

https://en.wikipedia.org/wiki/Birdshot_chorioretinopathy

... choroid diseases MeSH C11.941.160.177 - choroid hemorrhage MeSH C11.941.160.238 - choroid neoplasms MeSH C11.941.160.244 - ... disease MeSH C11.675.349.500.500 - Graves ophthalmopathy MeSH C11.675.504 - granuloma, plasma cell, orbital MeSH C11.675.659 - ... iris diseases MeSH C11.941.375.060 - aniridia MeSH C11.941.375.060.950 - WAGR syndrome MeSH C11.941.375.285 - exfoliation ... choroid neoplasms MeSH C11.941.855.400 - iris neoplasms MeSH C11.941.879 - uveitis MeSH C11.941.879.780 - panuveitis MeSH ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C11)

"The Glymphatic System in Central Nervous System Health and Disease: Past, Present, and Future". Annual Review of Pathology. 13 ... Choroid Plexus Histology 40x Choroid plexus Choroid plexus Choroid plexus Choroid plexus papilloma Tela choroidea This article ... The choroid plexus, or plica choroidea, is a plexus of cells that arises from the tela choroidea in each of the ventricles of ... A choroid plexus is in part of the roof of the fourth ventricle. The choroid plexus consists of a layer of cuboidal epithelial ...

https://en.wikipedia.org/wiki/Choroid_plexus

Genetic diseases and disorders, Disorders of choroid and retina). ... The disease causes a gradual loss of vision, starting with childhood night blindness, followed by peripheral vision loss and ... Even though the disease progression can vary significantly, there are general trends. The first symptom many individuals with ... While the complete mechanism of disease is not fully understood, the lack of a functional protein in the retina results in cell ...

https://en.wikipedia.org/wiki/Choroideremia

Garma-Aviña, A. (2000). "Excretory Plugs from the Choroid Plexus in the Cerebrospinal Fluid of Dogs with Neurological Disease: ... are calcified structures in the pineal gland and other areas of the brain such as the choroid plexus. Older organisms have ...

https://en.wikipedia.org/wiki/Corpora_arenacea

Due to sickle cell disease, vascular occlusion may occur in the conjunctiva, iris, retina, or choroid. Retinal changes occur ... Sickle cell disease is a systemic disease that affects several organs in the body. Management of the underlying disease can ... Numerous diseases that feature blood hyperviscosity similar to sickle cell disease can manifest as retinal venous tortuousity. ... At a young age, a great proportion of people living with sickle cell disease can develop retinal changes. Sickle cell disease ...

https://en.wikipedia.org/wiki/Sickle_cell_retinopathy

Severity of disease varies greatly by mutation, with some mutations causing disease in the first or second decade of life, and ... Because transthyretin is made in part by the choroid plexus, it can be used as an immunohistochemical marker for choroid plexus ... At least 114 disease-causing mutations in this gene have been discovered. While wild type TTR can dissociate, misfold, and ... The liver secretes TTR into the blood, and the choroid plexus secretes TTR into the cerebrospinal fluid. TTR was originally ...

https://en.wikipedia.org/wiki/Transthyretin

Disorders of choroid and retina, Varicella zoster virus-associated diseases, Herpes simplex virus-associated diseases). ... Urayama and his colleagues reported the disease that they saw in six Japanese patients. Since then the disease has been seen in ... Further progressed stages of the disease can cause blindness in the eye experiencing ARN. Though the disease may be present ... The disease is not limited to a specific gender. Most cases have been reported in young adults though children and the elderly ...

https://en.wikipedia.org/wiki/Acute_retinal_necrosis

With a median age upon diagnosis of 3.5 years, this lesion is often a disease of infancy. They often reside supratentorial in ... Choroid plexus papilloma, also known as papilloma of the choroid plexus, is a rare benign neuroepithelial intraventricular WHO ... Media related to Choroid plexus papilloma at Wikimedia Commons Choroid Plexus Papilloma MRI, CT, and pathology images from ... Recent researches have shown that choroid plexus papilloma and choroid plexus cancer may be distinguished from one another ...

https://en.wikipedia.org/wiki/Choroid_plexus_papilloma

A mutation in the tumor suppressor gene TP53 is usually characterized in this disease. Choroid plexus carcinomas typically ... A choroid plexus carcinoma (WHO grade III) is a type of choroid plexus tumor that affects the choroid plexus of the brain. It ... Choroid plexus Brain tumor Cancer of the brain Gopal P, Parker JR, Debski R, Parker JC (August 2008). "Choroid plexus carcinoma ... In the event of subtotal resection or widespread leptomeningeal disease, craniospinal irradiation is often used. Choroid plexus ...

https://en.wikipedia.org/wiki/Choroid_plexus_carcinoma

Disorders of choroid and retina, All stub articles, Disease stubs, Eye stubs). ... Often, doctors may order blood tests to check if the symptoms are caused by a viral disease rather than MFC. Treatments vary ... Multifocal choroiditis and panuveitis (MCP) is an inflammatory disorder of unknown etiology, affecting the choroid, retina, and ... The first description of the disease was written in 1973. Symptoms include blurry vision, with or without sensitivity to light ...

https://en.wikipedia.org/wiki/Multifocal_choroiditis_and_panuveitis

Disorders of choroid and retina, All stub articles, Disease stubs, Eye stubs). ...

https://en.wikipedia.org/wiki/Berlin's_edema

It sticks platelets together and promotes clotting; inhibiting this helps prevent heart disease. On the other hand, PTGS2 (COX- ... but also neutralized the changes of the retina and the choroid thickness caused by the injection of pro-inflammatory agents. ... Minghetti L, Pocchiari M (2007). "Cyclooxygenase‐2, Prostaglandin E2, and Microglial Activation in Prion Diseases". ... Mechanisms of COX-2 inhibitor risk to heart disease". Life Sciences. 88 (1-2): 24-30. doi:10.1016/j.lfs.2010.10.017. PMC ...

https://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase_2

The value of radiotherapy as well as chemotherapy on disease progression will need to be investigated in future trials. With ... These tumors were tested immunohistochemically with a profile similar to that of a choroid plexus tumor; however, ... the tumors appeared to be less differentiated than a choroid plexus papilloma and more differentiated than a choroid plexus ... choroid plexus papilloma, and metastatic papillary carcinoma. Papillary tumors characteristically show a discrete, compressive ...

https://en.wikipedia.org/wiki/Papillary_tumors_of_the_pineal_region

... familial paroxysmal Choriocarcinoma Chorioretinitis Chorioretinopathy dominant form microcephaly Choroid plexus cyst Choroid ... Marie-Tooth disease type 1A Charcot-Marie-Tooth disease type 1B Charcot-Marie-Tooth disease type 1C Charcot-Marie-Tooth disease ... Marie-Tooth disease type 2C Charcot-Marie-Tooth disease type 2D Charcot-Marie-Tooth disease type 4A Charcot-Marie-Tooth disease ... Tooth disease Charcot-Marie-Tooth disease Charcot-Marie-Tooth disease deafness dominant type Charcot-Marie-Tooth disease ...

https://en.wikipedia.org/wiki/List_of_diseases_(C)

Following the closure of the caudal neuropore and formation of the brain's ventricles that contain the choroid plexus tissue, ... Spinal cord injury can also be non-traumatic and caused by disease (transverse myelitis, polio, spina bifida, Friedreich's ...

https://en.wikipedia.org/wiki/Spinal_cord

Salmon JF (13 December 2019). "Retinal vascular disease". Kanski's clinical ophthalmology : a systematic approach (9th ed.). ... Disorders of choroid and retina, Ophthalmology). ...

https://en.wikipedia.org/wiki/Valsalva_retinopathy

... is a self-limiting disease that may affect both type 1 and type 2 diabetic patients. Unilateral or ... Articles with short description, Short description matches Wikidata, Disorders of choroid and retina). ... Ramanjit, Sihota; Radhika, Tandon (2015). Parsons' diseases of the eye (Twenty-second ed.). New Delhi, India. p. 369. ISBN 978- ... vascular leakage into and surrounding the optic nerve and disruption of axoplasmic flow resulting from microvascular disease of ...

https://en.wikipedia.org/wiki/Diabetic_papillopathy

"Retinal diseases - Symptoms and causes". Mayo Clinic. "Understanding how immune cells cause scarring in wet age-related macular ... Disorders of choroid and retina). ...

https://en.wikipedia.org/wiki/Macular_scarring

Other specified disordes of choroid (H31.9) Disorder of choroid, unspecified (H32) Chorioretinal disorders in diseases ... Other chorioretinal disorders in diseases classified elsewhere (H33) Retinal detachment - the retina detaches from the choroid ... International Statistical Classification of Diseases (WHO ICD-10) - Diseases of the eye and adnexa (ICD-10 codes H00-H59) ... This is a partial list of human eye diseases and disorders. The World Health Organization publishes a classification of known ...

https://en.wikipedia.org/wiki/Eye_disease

... disease 10% of patients have extra-adrenal (paraganglioma) disease 10% of patients have inherited (familial disease) Despite ... December 2019). "Vascular Changes in the Retina and Choroid of Patients With EPAS1 Gain-of-Function Mutation Syndrome". JAMA ... "Rare Disease Day 2021 - 28 Feb". Rare Disease Day - 28 Feb 2021. Retrieved 2020-08-26. "Home". NORD (National Organization for ... In patients with minimal disease burden, a "watch and wait" approach with frequent imaging to monitor disease is favorable, ...

https://en.wikipedia.org/wiki/Pheochromocytoma

Kaplan, MS, "Proliferation of Epithelial Cells in the Adult Primate Choroid Plexus," Anatomical Record, 197: 495-502, 1980. ... "Holter Monitoring for the Assessment of Silent Cardiac Ischemia in Cerebrovascular Disease," Archives of Physical Medicine and ...

https://en.wikipedia.org/wiki/Michael_Kaplan_(biologist)

The choroid plexus is the term still used today and are the structures that produce cerebrospinal fluid. Galen was one of the ... The treatise on Diseases II physicians are warned about the illnesses associated with air in the body, particularly in the ... Later in the Corpus, during or after the life of Aristotle on Disease IV, pneuma, or air is presented as a warming life force. ... In the treatise On the Sacred Disease air is described as not being located in just the lungs but in the entire body and ...

https://en.wikipedia.org/wiki/History_of_the_location_of_the_soul

Congenital disease occurs due to the acquisition of the organism by a pregnant woman exposed to tissue cysts or oocytes in ... Disorders of choroid and retina). ... Sometimes serologic testing is used to rule out the disease, ... In congenital toxoplasmosis, the disease is bilateral in 65-85% of cases and involves the macula in 58%. Chronic or recurrent ... Spontaneous abortion may result if the disease is acquired during the first trimester. Congenital toxoplasmosis may lead to ...

https://en.wikipedia.org/wiki/Toxoplasmic_chorioretinitis

... disease inflammatory bowel disease Whipple's disease systemic lupus erythematosus polyarteritis nodosa Kawasaki's disease ... Pan-uveitis is the inflammation of all layers of the uvea(Iris, ciliary body and choroid). Uveitis is usually an isolated ... Sympathetic ophthalmia Behçet disease Crohn's disease Fuchs heterochromic iridocyclitis Granulomatosis with polyangiitis HLA- ... Presence of this type of HLA allele has a relative risk of evolving this disease by approximately 15%. The most common form of ...

https://en.wikipedia.org/wiki/Uveitis

Thakker, Rajesh V.; Whyte, Michael P.; Eisman, John; Igarashi, Takashi (2013). Genetics of Bone Biology and Skeletal Disease. ... The disorder is characterized by the following: Hypogonadism Brachydactyly syndrome Choroid plexus calcification Hypoplasia of ... Genetic and Rare Diseases Information Center (GARD) - an NCATS Program. Retrieved 9 February 2017. Kottler, Marie (2004). " ...

https://en.wikipedia.org/wiki/Albright's_hereditary_osteodystrophy

Fellows rotate in the multiple sclerosis (MS) clinic, the neuro-HIV clinic and the neuro-infectious disease clinic at RUMC and ... He and his colleagues also demonstrated that JCV can infect meningeal and choroid plexus cells and cause JCV meningitis. They ... He is a founding member of the Neuro-infectious Disease Section and Global Health Section of the American Academy of Neurology ... While a medical student, he became interested in a new disease - acquired immune deficiency syndrome (AIDS).[citation needed] ...

https://en.wikipedia.org/wiki/Igor_J._Koralnik

"Facts About Stargardt Disease". NEI. April 2015. Retrieved 17 January 2019. Bernstein, M.D., Ph.D., Paul S. (3 November 2017 ... Disorders of choroid and retina). ... Since the abnormality is not in the eye lens, the disease is ... OMD that is caused by mutations of the retinitis pigmentosa 1-like 1 (RP1L1) gene (OMIM 608581) is called Miyake's disease. ... Given the possible relation between ABCA4 and OMD, progress with Stargardt disease via gene therapy might have a spillover ...

https://en.wikipedia.org/wiki/Occult_macular_dystrophy

A Rich focus develops within the choroid plexus or ventricular walls as a result of haematogenous dissemination. The mechanism ... v t e (Neurological disorders, All stub articles, Nervous system disease stubs). ...

https://en.wikipedia.org/wiki/Rich_focus

GRACILE syndrome Gyrate atrophy of choroid and retina Hydrolethalus syndrome 1 Infantile-onset spinocerebellar ataxia ( ... There are 36 rare diseases regarded as Finnish heritage diseases. The diseases are not restricted to Finns; they are genetic ... A Finnish heritage disease is a genetic disease or disorder that is significantly more common in people whose ancestors were ... The majority of genetic diseases reported in Finland are not part of the Finnish disease heritage and their prevalence is not ...

https://en.wikipedia.org/wiki/Finnish_heritage_disease

Other factors that contribute of the migration are slit proteins (produced at the choroid plexus) and their gradient (generated ... Andreas Hermann; Alexander Storch (2008). "Endogenous Regeneration in Parkinson's Disease: Do We Need Orthotopic Dopaminergic ... "Signaling pathways controlling neural stem cells slow progressive brain disease". Cold Spring Harb. Symp. Quant. Biol. 73: 403- ... research must be done to understand factors that affect progenitor cell differentiation in order to treat Parkinson's disease. ...

https://en.wikipedia.org/wiki/Endogenous_regeneration

A large study on people 65 years old or older, linked the development of Alzheimer's disease and other forms of dementia to the ... "Putative selective 5-HT-2 antagonists block serotonin 5-HT-1c receptors in the choroid plexus". The Journal of Pharmacology and ...

https://en.wikipedia.org/wiki/Chlorphenamine

It is used in a broad spectrum of diseases, for example, inflammation of scleral tissues, cornea, conjunctiva in dogs. In ... choroid and iris. Endophthalmitis, which is an infection of the eye involving the aqueous humor, Graves' Ophthalmopathy, Herpes ... "Herpetic Eye Disease Study: A Controlled Trial of Topical Corticosteroids for Herpes Simplex Stromal Keratitis". Ophthalmology ...

https://en.wikipedia.org/wiki/Topical_prednisolone

Mutations in SCARB2 have also been shown to cause Gaucher disease and myoclonic epilepsy, as LIMP-2 is critical for the proper ... "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes ... SCARB2 is a receptor for two viruses that cause hand, foot, and mouth disease in children, Enterovirus 71 and Coxsackievirus ... Mutations in LIMP-2 have been shown to cause Gaucher disease, myoclonic epilepsy, and action myoclonus renal failure syndrome. ...

https://en.wikipedia.org/wiki/SCARB2

Certain ocular diseases can come from sexually transmitted diseases such as herpes and genital warts. If contact between the ... The innermost is the retina, which gets its oxygenation from the blood vessels of the choroid (posteriorly) as well as the ... There are many diseases, disorders, and age-related changes that may affect the eyes and surrounding structures. As the eye ... With aging, the quality of vision worsens due to reasons independent of diseases of the aging eye. While there are many changes ...

https://en.wikipedia.org/wiki/Human_eye

RNF212 Refsum disease; 266500; PEX7 Refsum disease; 266500; PHYH Refsum disease, infantile form; 266510; PEX26 Refsum disease, ... PRPH2 Choroid plexus papilloma; 260500; TP53 Choroideremia; 303100; CHM Chromosome 22q13.3 deletion syndrome; 606232; SHANK3 ... PSEN1 Alzheimer disease-10; 104300; AD10 Alzheimer disease-2; 104310; APOE Alzheimer disease-4; 606889; PSEN2 Alzheimer disease ... RLBP1 Niemann-Pick disease, type A; 257200; SMPD1 Niemann-Pick disease, type B; 607616; SMPD1 Niemann-Pick disease, type C1; ...

https://en.wikipedia.org/wiki/List_of_OMIM_disorder_codes

... the choroid plexus, thalamus, hypothalamus, and the median eminence [35]. In the meninges, they are found within the dural ... Principles of Disease. Computing Centre, Slovak Academy of Sciences: Academic Electronic Press. ISBN 80-967366-1-2. Archived ...

https://en.wikipedia.org/wiki/Granulocyte

Diabetic Eye Disease National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIDDK/NIH ... Disorders of choroid and retina). ... Diabetic retinopathy (also known as diabetic eye disease), is a ... Aiello LP, Silva P, Cavallerano JD, Klein R (2016). "Diabetic Eye Disease". In Jameson JL, de Groot LJ (eds.). Endocrinology: ... Obstructive sleep apnea (OSA) has been associated with a higher incidence of diabetic eye disease due to blood desaturation ...

https://en.wikipedia.org/wiki/Diabetic_retinopathy

Cardiovascular disease is the leading cause of death in the world. Ischemic heart disease develops when stenosis and occlusion ... choroidal neovascularization is the formation of a microvasculature within the innermost layer of the choroid of the eye. ... "Cardiovascular diseases (CVDs)". World Health Organization. 17 May 2017. Retrieved 14 July 2020. Lassaletta, Antonio D.; Chu, ... This can occur in response to ischemic vascular diseases or increase demand (e.g. exercise training). Arteriogenesis is ...

https://en.wikipedia.org/wiki/Neovascularization

... targeted diseases (e.g. Alzheimer's or Parkinson's disease). Carbohydrate deficient transferrin increases in the blood with ... A major source of transferrin secretion in the brain is the choroid plexus in the ventricular system. The main role of ... Transferrin is an acute phase protein and is seen to decrease in inflammation, cancers, and certain diseases (in contrast to ... Kumar V, Hagler HK (1999). Interactive Case Study Companion to Robbins Pathologic Basis of Disease (6th Edition (CD-ROM for ...

https://en.wikipedia.org/wiki/Transferrin

The Contribution of Increased Choroid Plexus Volume in the Alzheimers Disease. Jiaxin Li1, Yueqin Hu2, Xue Feng 3, Weiying Dai ... Alzheimers disease (AD) may be caused by the dysfunction of glymphatic system, in which anatomic changes of the choroid plexus ... choroid larger years patient patients engineering proteins variance brain disease wilk volunteers enlarged database china ... Here, the lateral ventricle and choroid plexus were segmented using two cascaded deep learning models and the volumes were ...

https://archive.ismrm.org/2022/3261.html

Choroid Diseases / diagnosis* * Choroid Diseases / microbiology * Early Diagnosis * Eye / microbiology * Granuloma / diagnosis ... 4 Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa. ...

https://pubmed.ncbi.nlm.nih.gov/26907735/

Gyrate atrophy of the choroid and retina, which is often shortened to gyrate atrophy, is an inherited disorder characterized by ... Genetic and Rare Diseases Information Center. *Gyrate atrophy of choroid and retina ... Catalog of Genes and Diseases from OMIM. *GYRATE ATROPHY OF CHOROID AND RETINA ... Kaiser-Kupfer MI, Caruso RC, Valle D. Gyrate atrophy of the choroid and retina: further experience with long-term reduction of ...

https://medlineplus.gov/genetics/condition/gyrate-atrophy-of-the-choroid-and-retina/

Classification of image artefacts in optical coherence tomography angiography of the choroid in macular diseases. Clin Exp ... 6 It is also recognized that the inner choroid and the choriocapillaris disproportionally thin with age and disease.31 It is ... It is also recognized that the choroid tends to thin with age, with the nasal area being thinnest, and the subfoveal region ... 9. Chalam KV, Sambhav K. Optical Coherence Tomography Angiography in Retinal Diseases. J Ophthalmic Vis Res 2016; 11:84-92.. * ...

https://journals.lww.com/apjoo/Fulltext/2020/04000/Quantification_of_Optical_Coherence_Tomography.13.aspx

Optic atrophy is the final common morphologic endpoint of any disease process that causes axon degeneration in the ... that usually results from diseases of the choroid or the retina. The disc is waxy pale with normal disc margins, marked ... It is observed in diseases such as multiple sclerosis and Devic disease. ... that usually follows diseases of the choroid or the retina. ... Optic atrophy is not a disease but an end outcome thus, ...

https://www.medscape.com/answers/1217760-183170/which-age-groups-have-the-highest-prevalence-of-optic-atrophy

"Choroid plexus volume linked to Alzheimers disease," (Eurekalert [American Association for the Advancement of Science], May 17 ... "Youthful spinal fluid could help treat Alzheimers disease, study suggests," by Jon Hamilton (US National Public Radio _All ... "A new biomarker for blood-brain barrier dysfunction in Alzheimers disease," (Eurekalert [American Association for the ... Sting proteins efforts to clean up brain cell damage may speed Parkinsons disease progress," (Eurekalert [American ...

https://www.ssc.wisc.edu/cdha/info/archives/date/2022/05

When these lesions are identified clinically, they most often involve the choroid, but metastatic disease can affect any part ...

https://www.aao.org/bcscsnippetdetail.aspx?id=da8993d7-e4e1-46da-bdaa-aadeca9d1ba2

Cellular and physiological mechanisms underlying blood flow regulation in the retina choroid in health and disease. Prog Retin ... Classification of image artefacts in optical coherence tomography angiography of the choroid in macular diseases. Clin ... 26 With nearly 80 million people expected to suffer from the disease in 2020, and an increasing prevalence of disease with age ... offering potential to assist in the diagnosis of a variety of retinal diseases. To date, numerous retinal diseases, such as ...

https://bjo.bmj.com/content/101/1/16?ijkey=a7ce75a07411cf29eec70f8bb64c24589e00d8bc&keytype2=tf_ipsecsha

Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ... A) Choroid plexus endothelium. B) ependymal epithelium and subependymal tissue, including neurons. Rabbit α-NiV N protein ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... the Centers for Disease Control and Prevention, or the authors affiliated institutions. Use of trade names is for ...

https://wwwnc.cdc.gov/eid/article/18/12/12-0875-f6.htm

What is Von Willebrand Disease Type I, Type I vWD? Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood ... The choroid anchors the retina to the underlying structures and supplies it with oxygen and nourishment. CEA is a developmental ... Nevertheless, genetic age is the primary risk factor for numerous diseases in dogs, including cancer, kidney disease, ... This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to ...

https://my.embarkvet.com/dog/hayley2013

Choroid plexus tumors are graded based on the World Health Organization (WHO) classification scheme and include choroid plexus ... tumors derived from choroid plexus epithelium that are seen predominantly in children. ... Choroid plexus neoplasms are rare, intraventricular, primary central nervous system (CNS) ... Choroid plexus papilloma. A new presentation of von Hippel-Lindau (VHL) disease. Eye (Lond). 1992. 6 ( Pt 1):90-2. [QxMD ...

https://emedicine.medscape.com/article/1744050-overview

Choroid 73. CHOROID 73 00 00 Disease, choroid NOS 73 00 40 Tear, choroid, (traumatic) 73 00 40 Trauma, choroid NEC or NOS 73 00 ... choroid 73 50 00 Tumor, choroid NOS 73 53 00 Nevus, choroid (benign) 73 53 00 Tumor, choroid, benign 73 56 00 Tumor, choroid, ... choroid NOS (focal) (pigment) 73 70 00 Hemorrhage, choroid 73 99 00 Disease, choroid, type specified NEC 73 99 00 Pigment, ... disease 76 27 00 Disease, Coats 76 28 00 Disease, Eales 76 28 00 Eales disease 76 30 00 Retinopathy, central serous NOS 76 ...

https://wonder.cdc.gov/wonder/sci_data/surveys/hanes/hanes1/type_txt/h1optha.asp

Diseases of the Choroid and Retina. These diseases can be detected only by means of the ophthalmoscope, but may be foretold by ... Common Diseases of the Eye. IN addition to errors of refraction, there are certain diseases of the eye and its appendages ... Syphilis and kidney disease are common causes.. Atrophy of the Optic Nerve. This is a very serious progressive disease, ... There is evidence to show that a certain number of eye diseases-or rather the tendency to these diseases-may be acquired by ...

https://www.central-fixation.com/strengthening-the-eyes/chapter-12.php

Choroid Diseases 1 0 Choroidal Neovascularization 1 0 Wet Macular Degeneration 1 0 ... in Genopedia reflects only the indexed disease term without children terms, but the number in the HuGE Literature Finder ... reflects all text searches of the disease term including the indexed term and corresponding children terms. ...

https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=POLR2B&geneID=5431&typeSubmit=GO&check=y&typeOption=gene&which=2&pubOrderType=pubD

ICD 10 code for Diffuse secondary atrophy of choroid, bilateral. Get free rules, notes, crosswalks, synonyms, history for ICD- ... Diseases of the eye and adnexa. Note*Use an external cause code following the code for the eye condition, if applicable, to ... Diffuse secondary choroid atrophy, both eyes. ICD-10-CM H31.123 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0): * ... Diffuse secondary atrophy of choroid, bilateral. 2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code *H31.123 is a ...

https://www.icd10data.com/ICD10CM/Codes/H00-H59/H30-H36/H31-/H31.123

Background: Changes in choroidal vascularity index (CVI) are associated with multiple choroid-related ocular diseases. CVI is ... Background: A wide range of diseases, such as systemic sclerosis, can be diagnosed by imaging the nailfold microcirculation, ... It is uncertain whether ocular microvascular alterations are associated with this disease. In this study, we evaluated retinal ... Background: Sjögren syndrome (SjS) is a systemic disease affecting exocrine, including ocular lacrimal, glands. ...

http://www.octnews.org/publisher/34782/home/

Choroid plexus obtained at autopsy from paediatric and adult patients with unrelated diseases served as control. The average ... Choroid plexus obtained at autopsy from paediatric and adult patients with unrelated diseases served as control. The average ... MIB-1 immunoreactivity reveals different labelling in low-grade and in malignant epithelial neoplasms of the choroid plexus. ... MIB-1 immunohistochemistry was carried out on a retrospective biopsy series of epithelial choroid plexus neoplasms in order to ...

https://www.zora.uzh.ch/id/eprint/1773/

Disease involvementi Disease related keywords assigned by UniProt combined with Cancer-related genes and FDA approved drug ... Disease involvementi Disease related keywords assigned by UniProt combined with Cancer-related genes and FDA approved drug ... Choroid plexus [nTPM] * Colon [nTPM] * Duodenum [nTPM] * Endometrium 1 [nTPM] * Epididymis [nTPM] ...

http://www.proteinatlas.org/search/protein_class:Adrenal+gland+diseases

The disease attacks the macula of the eye, where our sharpest central vision occurs, affecting reading, driving, identifying ... The MC degranulation spills enzymes and cytokines into choroid that could cause RPE and CC death and also cause the thinning of ... Inflammatory Cells In Choroid During Age-Related Macular Degeneration in Relationship to Retinal Pigmented Epithelium (RPE) ... Inflammatory Cells In Choroid During Age-Related Macular Degeneration in Relationship to Retinal Pigmented Epithelium (RPE) ...

https://www.brightfocus.org/macular/grant/inflammatory-cells-choroid-during-age-related-macular-degeneration-relationship

... formed by the choroid plexus epithelial (CPE) cells, releases an increased amount of EVs into the CSF in response to peripheral ... play an important role in the pathogenesis of Alzheimers disease (AD). We previously reported that the blood-cerebrospinal ... Balusu S, Brkic M, Libert C, Vandenbroucke RE (2016) The choroid plexus-cerebrospinal fluid interface in Alzheimers disease: ... Spector R, Johanson CE (2013) Sustained choroid plexus function in human elderly and Alzheimers disease patients. Fluids ...

https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-021-01245-z

In the 52 years since the original description of Menkes kinky hair disease (MKHD), advances in understanding the clinical, ... ATP7A gene addition to the choroid plexus results in long-term rescue of the lethal copper transport defect in a Menkes disease ... Drugs & Diseases , Pediatrics: Genetics and Metabolic Disease Genetics of Menkes Kinky Hair Disease Medication. Updated: Apr 17 ... Wilsons disease and Menkes disease. Am J Physiol. 1999 Feb. 276(2 Pt 1):G311-4. [QxMD MEDLINE Link]. ...

https://emedicine.medscape.com/article/946985-medication

Choroid Diseases 1 0 Coronary Aneurysm 1 0 Diabetes Mellitus, Type 2 1 0 ... in Genopedia reflects only the indexed disease term without children terms, but the number in the HuGE Literature Finder ... reflects all text searches of the disease term including the indexed term and corresponding children terms. ...

https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=SKIV2L&geneID=6499&typeSubmit=GO&check=y&typeOption=gene&which=2&pubOrderType=pubD

Choroid Disease Choroidal Disease Choroidal Diseases Disease, Choroid Disease, Choroidal Diseases, Choroid Diseases, Choroidal ... Choroid Disease. Choroidal Disease. Choroidal Diseases. Disease, Choroid. Disease, Choroidal. Diseases, Choroid. Diseases, ... Choroid Diseases - Preferred Concept UI. M0024286. Scope note. Disorders of the choroid including hereditary choroidal diseases ... Disorders of the choroid including hereditary choroidal diseases, neoplasms, and other abnormalities of the vascular layer of ...

https://decs.bvsalud.org/en/ths/resource/?id=24564

Choroid plexus. Apical membrane. Protein. Human. Mouse. Ovary. mRNA. Human. Thyroid gland. mRNA. Human. ... Health/Disease Relation. Reference. MCT1, 2, 4. High expression in many cancer types, including breast, bone, colon, bladder, ... Monocarboxylate Transporters in Health and Disease. Melanie A. Felmlee, Robert S. Jones, Vivian Rodriguez-Cruz, Kristin E. ... Monocarboxylate Transporters in Health and Disease. Melanie A. Felmlee, Robert S. Jones, Vivian Rodriguez-Cruz, Kristin E. ...

https://pharmrev.aspetjournals.org/content/72/2/466/tab-figures-data

Thus, it has been suggested earlier that the central nervous system might play an important role in the disease. ... The choroid plexus located in the brain ventricle is marked with red in the brain image. The volume of the choroid plexus was ... As the choroid plexus is known to mediate the interaction between inflammation in the periphery of the body and in the brain, ... The dots in the graph show the volume of the choroid plexus in patients with CRPS (on the left) and healthy control subjects ( ...

https://www.technologynetworks.com/neuroscience/news/unexpected-link-between-choroid-plexus-chronic-pain-0-283621

The choroid is the layer of tissue between the retina and sclera. Rich with blood vessels, it provides nutrients and regulates ... Chorioretinitis - Inflammation of the choroid caused by infection or an autoimmune disease. ... Choroid anatomy. The choroid is part of the uvea, which also consists of the iris and the ciliary body. The iris and ciliary ... What is the choroid?. The choroid is the middle layer of tissue in the wall of the eye. Its found between the sclera (the ...

https://www.allaboutvision.com/eye-care/eye-anatomy/choroid/

Get or read online The Choroid Plexus And Cerebrospinal Fluid book ... FREE DOWNLOAD The Choroid Plexus And Cerebrospinal Fluid book in PDF, EPUB and Kindle format. ... Role of the Choroid Plexus in Health and Disease by Jeppe Praetorius,Bonnie Blazer-Yost,Helle Damkier. ... The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in CNS Development, Maintenance, and Disease Progression combines ...

https://harperandharley.org/pdf/the-choroid-plexus-and-cerebrospinal-fluid/

The 2023 Gordon Research Conference on Neuroimmune Communication in Health and Disease will be held in Ventura, CA. Apply today ... Breaking The Barrier: Modelling SARS-CoV-2 Infection In Choroid Plexus Organoids ... autoimmune diseases, tissue inflammation, and infectious diseases, including COVID-19. We aim to have dynamic discussions ... Conference History Neuroimmune Communication in Health and Disease (GRS) Contribute Financially to This Conference Conference ...

https://www.grc.org/neuroimmune-communication-in-health-and-disease-conference/2023/

The Rhythmicity of Clock Genes is Disrupted in the Choroid Plexus of the APP/PS1 Mouse Model of Alzheimers Disease. Journal of ... 2021). A Computational Analysis in a Cohort of Parkinsons Disease Patients and Clock-Modified Colorectal Cancer Cells Reveals ... Clinical applications of exercise in Parkinsons disease: what we need to know? Expert Rev Neurother. Doi: 10.1080/ ... a Cross-Platform Study of Colorectal Cancer Time-Series Data Reveals an Association with Genes Involved in Huntingtons Disease ...

https://www.medicalschool-hamburg.de/forschung-institute-labs/forschungsinstitute/ism-institute-for-systems-medicine/publikationen/

Choroid diseases; Macular degeneration; Disease attributes; Age of onset; Sex distributiony. Abstract： Objective To compare ... Chinese Journal of Ocular Fundus Diseases. Issue:. Volume 28, Issue 05, 2012. DOI:. 10.3760/cma.j.issn.1005-1015.2012.05.004. ... Your Position: Home > Journal List > Chinese Journal of Ocular Fundus Diseases > Paper ... gender and disease laterality between nAMD and PCV patients.Results The mean age at diagnosis of nAMD group and PCV group were ...

https://eng.med.wanfangdata.com.cn/PaperDetail.aspx?qkid=zhydb&qcode=zhydb201205004

In other words, with the light source directed off to the lesion's side, the affected retina and choroid exhibited a reddish glow. (reviewofoptometry.com)
The idea is that the transfected cells in the eye allow for sustained local production of therapeutic proteins, which can then produce effects in a variety of structures in the eye, including the retina and choroid. (medgadget.com)
2 Posterior uveitis involves the retina and choroid and accounts for 9.3-38% of all uveitis cases. (touchophthalmology.com)
[ 1 ] The basis for this classification was that these disorders occurred primarily in young adult women, affected the outer retina and choroid, and were associated with inflammation, visual field loss, and in some instances, electroretinogram abnormalities. (medscape.com)

Choroid plexus tumors are graded based on the World Health Organization (WHO) classification scheme and include choroid plexus papilloma (CPP) (WHO grade I) (see the following image), atypical choroid plexus papilloma (WHO grade II), and choroid plexus carcinoma (CPC) (WHO grade III). (medscape.com)
This coronal T1-weighted magnetic resonance image (MRI) following contrast administration shows a homogeneously enhancing choroid plexus papilloma within the right lateral ventricle of a 1-year-old boy. (medscape.com)
High MIB-1 labelling indices were associated with less favourable post-operative outcome in choroid plexus carcinomas and in one papilloma with atypical histology. (uzh.ch)
Choroid plexus papilloma - Rare, benign brain tumor that develops in the choroid plexus (tissue that makes cerebrospinal fluid). (allaboutvision.com)

In addition, retinal and choroidal vessel density and blood flow can be quantified, offering potential to assist in the diagnosis of a variety of retinal diseases. (bmj.com)
Background: Changes in choroidal vascularity index (CVI) are associated with multiple choroid-related ocular diseases. (octnews.org)
Disorders of the choroid including hereditary choroidal diseases, neoplasms, and other abnormalities of the vascular layer of the uvea. (bvsalud.org)
Choroidal detachment - A " serous choroidal detachment " occurs when fluid fills between the sclera and choroid. (allaboutvision.com)
Hemorrhagic choroidal detachment - A " hemorrhagic choroidal detachment " occurs when blood fills the space between the sclera and choroid, such as when a blood vessel bursts. (allaboutvision.com)
Choroidal rupture - A tear in the choroid, Bruch's membrane and the retinal pigment epithelium (RPE) that result from an eye injury. (allaboutvision.com)
One classic disease that causes the choroidal capillaries to leak more than they should is central serous retinopathy. (retinavitreous.com)
Pachychoroid disease spectrum encompasses central serous chorioretinopathy,polypoidal choroidal vasculopathy,pachychoroid pigment epitheliopathy,pachychoroid neovasculopathy,focal choroidal excavation,peripapillary pachychoroid syndrome and peripheral exudative hemorrhagic chorioretinopathy,etc. (bvsalud.org)
Choroidal endothelial cells (CECs) are important for the vascular integrity of the choroid, but the effects of corticosteroid effects in these cells are unknown. (bvsalud.org)
A choroidal hemangioma is a benign, vascular tumor of the choroid that is composed predominately of large, dilated, thin-walled vessels with minimal stroma. (reviewofoptometry.com)
Increased choroidal thickness can be seen using enhanced depth imaging OCT in inflammatory disorders of the choroid, particularly in Vogt-Koyanagi-Harada disease, as well as other causes of posterior uveitis. (medscape.com)
Diagnosed or Treated Age-related macular degeneration (AMD) includes diagnosis codes specifying degenerative diseases of the macula, including macula drusen, dry-form AMD (including geographic atrophy), and wet-form AMD (including active choroidal neovascularization). (cdc.gov)

Currently we lack a reliable, noninvasive vascular biomarker to monitor both the "healthy" aging and disease progression of age-related macular degeneration (AMD). (lww.com)
When growing in places they shouldn't, they can cause disease, such as wet age-related macular degeneration (AMD). (fightingblindness.org)
Best disease is an inherited form of juvenile macular degeneration characterized by a loss of central vision. (fightingblindness.org)
Structural OCT and OCT angiographies are essential to differentiate this entity from age related macular degeneration diseases, characterized by thin choroid. (itmedicalteam.pl)
FAF has been used for the detection and monitoring of diseases that affect the RPE, such as nonexudative age-related macular degeneration, medication toxicity, vitelliform dystrophies and inherited retinal diseases. (medscape.com)

Choroid plexus neoplasms can produce hydrocephalus and increased intracranial pressure by a number of mechanisms, including obstruction of normal cerebrospinal fluid (CSF) flow, overproduction of CSF by the tumor itself, local expansion of the ventricles, or spontaneous hemorrhage. (medscape.com)
We previously reported that the blood-cerebrospinal fluid (CSF) interface, formed by the choroid plexus epithelial (CPE) cells, releases an increased amount of EVs into the CSF in response to peripheral inflammation. (biomedcentral.com)
You could read this book directly on your devices with pdf, epub and kindle format, check detail and related The Choroid Plexus and Cerebrospinal Fluid books below. (harperandharley.org)
The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in CNS Development, Maintenance, and Disease Progression combines new and established work to allow for cross-disciplinary discussion and showcase newfound excitement surrounding the choroid plexus and cerebrospinal fluid (CSF). (harperandharley.org)
This book highlights the importance of the choroid plexus, which forms the blood-cerebrospinal fluid barrier and is the site of the major production of the cerebrospinal fluid (CSF). (harperandharley.org)
Located in the walls of the brain ventricles, the choroid plexus is best known for producing cerebrospinal fluid, which forms a protective mechanical cushion and immunological buffer for the brain. (technologynetworks.com)

Choroid plexus neoplasms are rare, intraventricular, primary central nervous system (CNS) tumors derived from choroid plexus epithelium that are seen predominantly in children. (medscape.com)
The overall annual incidence of choroid plexus neoplasms for all ages is 0.3 cases per million. (medscape.com)
[ 2 , 3 ] In adults, they account for less than 1% of primary intracranial neoplasms, whereas choroid plexus tumors represent up to 5% of pediatric brain tumors, and up to 20% of those arising in children aged 1 year and younger. (medscape.com)
The vast majority of choroid plexus neoplasms arise within the ventricles. (medscape.com)
The third ventricle is the least common intraventricular location for choroid plexus neoplasms, irrespective of patient age. (medscape.com)
MIB-1 immunoreactivity reveals different labelling in low-grade and in malignant epithelial neoplasms of the choroid plexus. (uzh.ch)
MIB-1 immunohistochemistry was carried out on a retrospective biopsy series of epithelial choroid plexus neoplasms in order to assess the proliferation rate of tumour cells. (uzh.ch)
Analysis of growth fraction by MIB-1 immunohistochemistry may prove a useful ancillary method for assessing the malignant potential of choroid plexus neoplasms. (uzh.ch)

Irrespective of patient age, choroid plexus papillomas outnumber choroid plexus carcinomas by a 5:1 ratio. (medscape.com)
Choroid plexus carcinomas are also far more common in the pediatric population, with approximately 80% of choroid plexus carcinomas occurring in children. (medscape.com)
Choroid plexus carcinomas occasionally arise in association with hereditary cancer predisposition syndromes, including the Li-Fraumeni and rhabdoid predisposition syndromes, with germline mutations of TP53 and hSNF5/INI1/SMARCB1, respectively. (medscape.com)
Seeding of the CSF may be seen even in benign choroid plexus papillomas, but leptomeningeal dissemination is much more common in choroid plexus carcinomas. (medscape.com)

This is unknown and relevant since inflammation and complement activation have been implicated in AMD previously and the cell types assessed can contribute to a pro-inflammatory environment in choroid. (brightfocus.org)
Chorioretinitis - Inflammation of the choroid caused by infection or an autoimmune disease. (allaboutvision.com)
As the choroid plexus is known to mediate the interaction between inflammation in the periphery of the body and in the brain, it is an interesting and important target for future research of chronic pain and CRPS in particular,' continues Hari. (technologynetworks.com)
Based on the history and the clinical presentation of multiple creamy white fundus lesions at the level of the choroid, with vitreous inflammation, we were very suspicious that our patient had "birdshot chorioretinopathy," a rare autoimmune inflammatory condition of the choroid and retina. (reviewofoptometry.com)
How are uncultivated and independent Acres of Chronic Inflammation permeability to Chronic Disease bushes? (iamtheopposition.com)
[ 3 ] suggested an ischemic choroidopathy, which resulted from primary inflammation of the choriocapillaris, as the unifying pathogenesis of these diseases. (medscape.com)

Optical coherence tomography angiography is one such technology that seeks to improve diagnostics for retinal diseases. (bmj.com)
To date, numerous retinal diseases, such as open-angle glaucoma, have been found to possess a vascular component. (bmj.com)
We see four key treatment approaches being used now for retinal diseases, and each of these have a variety of limitations, but some of the main issues are that treatments have a limited duration of any positive effect, they require frequent readministration or ongoing medical or lab monitoring, and in some cases there is a lack of full retinal exposure or poor ocular bioavailability of the treatment. (medgadget.com)

which is the specialized light-sensitive tissue that lines the back of the eye, and in a nearby tissue layer called the choroid. (medlineplus.gov)
This study will document the inflammatory cells that lie in the choroid of the eye, a layer of blood vessels and connective tissue that lies below the retina, and how they may contribute to this death, if activated. (brightfocus.org)
The goal of this study is to document for the first time the number and activation of the inflammatory cells including MC, microglia (retinal macrophages) and tissue macrophages (TM) in choroid during AMD and determine their relationship to RPE atrophy and vascular attenuation. (brightfocus.org)
The choroid is the middle layer of tissue in the wall of the eye. (allaboutvision.com)
Bruch's membrane - Thin layer of tissue located on the innermost part of the choroid. (allaboutvision.com)
New research from Hong Kong suggests that green tea may protect against eye diseases such as glaucoma because the researchers found green tea antioxidants called catechins present in various tissue structures in the eyes of laboratory rats after they had ingested green tea. (medicalnewstoday.com)
High-resolution 3-T MR imaging helps characterize orbital and ocular soft-tissue lesions, permitting superior delineation of orbital soft tissues, cranial nerves, blood vessels, and blood flow and detection of intracranial extension of orbital disease. (radiologykey.com)
The different transmission characteristics of NiV-Malaysia and NiV-Bangladesh might be attributable to differences in infectivity and pathogenicity of virus strains and in tissue tropism, reflected by higher incidence of respiratory disease in NiV-Bangladesh-infected patients ( 14 , 21 ). (cdc.gov)

Gyrate atrophy of the choroid and retina, which is often shortened to gyrate atrophy, is an inherited disorder characterized by progressive vision loss. (medlineplus.gov)
Optic atrophy is the final common morphologic endpoint of disease process that causes degeneration of axons of the ganglion cells. (medscape.com)
Our preliminary studies suggest that MC degranulation is associated with RPE atrophy and formation of choroid neovascularization (CNV) in AMD. (brightfocus.org)

Abnormalities of the outer retina, particularly in the photoreceptor inner/outer segment junction, can be seen on OCT in a variety of posterior inflammatory disorders, including birdshot chorioretinopathy, multiple evanescent white dot syndrome, acute posterior multifocal placoid pigment epitheliopathy, acute zonal occult outer retinopathy, multifocal choroiditis and Vogt-Koyanagi-Harada disease. (medscape.com)
FAF is useful to evalute disease activity in a number of posterior inflammatory disorders, particularly serpiginous chorioretinopathy, acute zonal occult outer retinopathy and multifocal choroiditis. (medscape.com)
Uveitis is an inflammatory eye disease affecting the iris, ciliary body, and choroid that can lead to symptoms ranging from redness, pain, and blurred vision to markedly diminished acuity in the setting of severe or chronic disease. (touchophthalmology.com)
The fundus displayed a pathologic phenomenon that was diagnosed as chorioretinitis, a form of posterior uveitis, which is an inflammatory response involving both the choroid layer, and the retina. (cdc.gov)

These OCT images illuminate specific findings along the layers of the posterior segment, including the choroid. (reviewofoptometry.com)
2 The broad disease entity of uveitis can be further classified into the anatomical divisions of anterior, intermediate, posterior, and panuveitis. (touchophthalmology.com)
Two brothers had regional involvement of the posterior pole with disturbances of retinal function attributable to localized disease, and there was only mild progression in these patients. (elsevier.com)
They can be classified as anterior uveal melanomas when the tumor arises in the iris and as posterior uveal melanomas when it arises in either the choroid or the ciliary body. (medscape.com)

The choroid is part of the uvea , which also consists of the iris and the ciliary body . (allaboutvision.com)
The uvea is subdivided into the iris, ciliary body, and choroid. (medscape.com)

CVI is calculated as the area/volume ratio of vessels in the choroid, which could be affected by alterations in regional signal intensities due to hypo-transmission defects (hypoTDs) caused by drusen and retinal pigment epithelium (RPE) detachments, and hyper-transmission defects (hyperTDs) caused by the absence of RPE. (octnews.org)
That is why it is sometimes used in conjunction with fluorescein to evaluate and manage disease of the choroid and retinal pigment epithelium. (retinavitreous.com)
The origin of the disease begins in choroid and later involves the retinal pigment epithelium. (reviewofoptometry.com)
The initial evaluation in one patient demonstrated diffuse disease involving retinal pigment epithelium and choriocapillaris with severe widespread disturbance of retinal function. (elsevier.com)

Here, the lateral ventricle and choroid plexus were segmented using two cascaded deep learning models and the volumes were measured on 733 subjects. (ismrm.org)

When these lesions are identified clinically, they most often involve the choroid, but metastatic disease can affect any part of the uvea. (aao.org)
Can be very difficult to distinguish from other infectious processes or metastatic disease when in the form of an abscess or tuberculoma. (neurosurgicalatlas.com)

The choroid plexus epithelial (CPE) cells form the blood-CSF barrier and provide an active interface between the CSF and the blood. (biomedcentral.com)

Eyevensys , a clinical-stage biotechnology company based in France, has developed a method to perform non-viral gene therapy in the eye, with the aim of treating ocular diseases. (medgadget.com)
Please give us an overview of the limitations of current treatments for ocular diseases. (medgadget.com)

Aparicio Sánchez JL,Balaguer A. La presencia de lesiones quísticas bilaterales múltiples en ecografía cerebral neonatal podría sugerir una patología subyacente. (evidenciasenpediatria.es)

For example, Hoh et al 1 found that in patients with OAG, OCT showed RNFL and macula thinning with disease progression. (bmj.com)

Our previous work showed significantly increased choroid plexus volume in AD patients compared to healthy controls. (ismrm.org)
Choroid plexus obtained at autopsy from paediatric and adult patients with unrelated diseases served as control. (uzh.ch)
When studying magnetic resonance images of the brains of patients suffering from CRPS, we noticed that the choroid plexus was nearly one-fifth larger in patients than in healthy control subjects,' says Postdoctoral Researcher Guangyu Zhou from Aalto University Department of Neuroscience and Biomedical Engineering, who analyzed the images. (technologynetworks.com)
The dots in the graph show the volume of the choroid plexus in patients with CRPS (on the left) and healthy control subjects (on the right). (technologynetworks.com)
For unknown reasons, sometimes a blood vessel network will grow in patients with macular disease. (retinavitreous.com)
Patients with VHL disease harbour a single mutation allele in the tumour suppressor gene VHL (3p25-p26). (nature.com)
Therefore, and due to the lack of effective therapies for diffuse or recurrent disease, there is an urgent demand for effective drugs for VHL patients, especially those medicines that might halt the progression of tumours and subsequently delay surgical treatment. (nature.com)
In fact, one Japanese study found the patients with Alzheimer's disease who had shown severe cognitive decline, anxiety, apathy, agitation, and irritability noted an improvement in their symptoms after supplementing with turmeric powder for one year. (naturalnews.com)
In our phase I/II trial studied patients with advanced stages of disease, and based on the data from part 1 of the study, we saw therapeutic protein expression up to 8 months after treatment. (medgadget.com)
En revanche, les patients de moins de cinq ans et ceux avec un diagnostic de cancer provisoire posé initialement bénéficiaient du délai total médian le plus court. (who.int)
Nous suggérons de mettre en place des programmes de formation médicale continue, d'améliorer l'accès aux services de diagnostic, et de faciliter l'orientation-recours de façon à donner la priorité aux patients suspects de cancer et ainsi raccourcir le délai de diagnostic. (who.int)

The choroid layer begins in the peripheral edges of the eyeball and lines the entire back of it, sandwiched between the sclera and the retina. (allaboutvision.com)
When they examined the cornea, lens, retina, choroid-sclera, vitreous humor, and aqueous humor, they found evidence that these various eye structures had absorbed singificant amounts of individual catechins. (medicalnewstoday.com)
The eye is composed of the cornea (clear outer covering), conjunctiva (white part), iris (colored part), and the eye wall (choroid, retina, and sclera). (cdc.gov)

It is rarely limited to the retina, but is commonly associated with diseases of the choroid ( CHORIORETINITIS ) and of the OPTIC DISK (neuroretinitis). (nih.gov)

Diagnosis codes are based on the International Classification of Diseases (ICD) system. (cdc.gov)

It usually remains hidden behind the iris diaphragm, growing undetected for longer periods of time than melanoma in the iris or choroid. (medscape.com)

The focus on the choroid plexus provides a practical resource on modeling clinical issues influenced by this brain region for researchers from students to principal investigators. (harperandharley.org)
Aalto University neuroscientists, in collaboration with researchers at Helsinki University Hospital and Harvard Medical School, have found a novel connection between the size of the choroid plexus in the brain and complex regional pain syndrome (CRPS). (technologynetworks.com)
The choroid plexus located in the brain ventricle is marked with red in the brain image. (technologynetworks.com)
for example, the size of the choroid plexus is not quantified in routine brain scans,' explains Professor Riitta Hari, who was in charge of the research. (technologynetworks.com)
Is brain calcification the cause of Alzheimer's disease? (naturalnews.com)
Intracranial calcifications can accumulate in a person's brain as they age and can affect brain structures such as the choroid plexus, the pineal gland, and the habenula. (naturalnews.com)
One known feature of Alzheimer's disease is the formation of amyloid plaques in the brain. (naturalnews.com)
Should brain calcification prove to be the primary driver of Alzheimer's, finding ways to inhibit this calcification could therefore be a good strategy for preventing or treating the disease. (naturalnews.com)
The aggregation and deposition of amyloid-β (Aβ) in the brain is thought to be an early event in the pathology of Alzheimer's disease (AD). (semcs.net)

Experimentally, elevated IOPs have produced delayed circulation times, most notably in the peripapillary choroid. (bmj.com)

The pathophysiological changes in the choroid plexus (CP) lead to impaired clearing of Aβ from the CSF, thereby further aggravating the disease pathology. (biomedcentral.com)

Alzheimer's disease (AD) may be caused by the dysfunction of glymphatic system, in which anatomic changes of the choroid plexus may be associated with reduced CSF production. (ismrm.org)
22. "Comorbidities can increase plasma biomarker levels associated with Alzheimer's disease," (Eurekalert [American Association for the Advancement of Science], May 26, 2022). (wisc.edu)
Furthermore, this imaging modality may provide insight to neural pathologies with vascular components such as Alzheimer's disease. (bmj.com)
Increasing evidence indicates that extracellular vesicles (EVs) play an important role in the pathogenesis of Alzheimer's disease (AD). (biomedcentral.com)
Alzheimer's disease (AD) is a progressive neurodegenerative disease mainly affecting the elderly population and accounting for 60-80% of dementia cases [ 1 ]. (biomedcentral.com)
Natural News ) As Alzheimer's disease continues to grow in prevalence around the world, scientists are searching frantically for a cure. (naturalnews.com)
The Journal of Alzheimer's Disease is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer's disease. (semcs.net)
The journal is dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer's disease. (semcs.net)
Alzheimer's disease (AD) is known to be caused by multiple factors, meanwhile the pathogenic mechanism and development of AD associate closely with genetic factors. (biomedcentral.com)
Alzheimer's disease (AD) is recognized as the most common neurodegenerative disease and a typical hippocampal amnesia, and also one of the dominating deadly disease affecting elderly population. (biomedcentral.com)

Our nonproprietary analysis of the vascular density of the choriocapillaris revealed a significant drop off of VD with age and disease, but further work is required to corroborate this finding. (lww.com)
If repeatable, choriocapillaris VD may provide a noninvasive biomarker of healthy aging and disease. (lww.com)
The choriocapillaris (CC) is the only source of oxygen and nutrition for photoreceptors (cells that sense light) and RPE cells (cells that transport molecules between choroid and retina). (brightfocus.org)

17 These findings and the possible association of normal tension glaucoma with vasospastic angina, migraine headache, and Raynaud's disease 18-20 add further support to a vascular contribution to glaucomatous optic nerve damage. (bmj.com)

In this study, expression of various stress proteins in the Alzheimer-diseased choroid plexus (CP) was assessed immunohistochemically. (semcs.net)
Eyevensys is also investigating the potential to deliver genes that encode for other proteins with utility in a variety of ophthalmic diseases, such as glaucoma and retinitis pigmentosa. (medgadget.com)

The Neuroimmune Communication in Health and Disease GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. (grc.org)
This GRC will be held in conjunction with the "Neuroimmune Communication in Health and Disease" Gordon Research Seminar (GRS). (grc.org)

4 Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa. (nih.gov)
NiV-Malaysia emerged in 1998 during an outbreak of infectious respiratory and neurologic disease in commercially farmed pigs, presumably after virus spillover from Malaysian flying foxes ( 2 ). (cdc.gov)

Mutations in BEST1 cause five distinct retinal degenerative diseases, including adult vitelliform macular dystrophy (AVMD), autosomal recessive bestrophinopathy (ARB), autosomal dominant vitreoretinochoroidopathy (ADVIRC), and retinitis pigmentosa (RP). (ox.ac.uk)

The MC degranulation spills enzymes and cytokines into choroid that could cause RPE and CC death and also cause the thinning of choroid, which is associated with both dry and wet AMD. (brightfocus.org)

This book is of great utility to neuroscientists interested in biological questions about cancer, multiple sclerosis, Alzheimer's, choroid plexus, or CSF research, and especially for researchers looking to expand their research into later stages of their disease of interest, such as metastasis. (harperandharley.org)

One of the major consequences of the lack of a functional VHL protein in von Hippel-Lindau disease, a rare cancer, is the constitutive activation of the HIF pathway. (nature.com)
Moreover, Green Med Info points out that sleep disturbances are considered a driver of Alzheimer's because wakefulness raises the levels of the amyloid beta protein that has been linked to the disease, whereas sleep reduces it. (naturalnews.com)

CONTEXT: Central serous chorioretinopathy (CSC) is a severe ocular disease characterized by fluid accumulation under the retina and abnormalities in the underlying vascular layer, the choroid. (bvsalud.org)

The thickness of the choroid varies depending on what part of the eye it's lining. (allaboutvision.com)

Most infections Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. (lecturio.com)

To determine if histograms of ADC can be used to differentiate ventricular ependymomas, choroid plexus papillomas (CPPs), and central neurocytomas (CNCs). (medscimonit.com)

In this work, we demonstrate the therapeutical properties of ICI-118,551 in VHL-derived CNS-Hemangioblastoma primary cultures, becoming a promising drug for VHL disease and other HIF-related diseases. (nature.com)

This paper reviews the pathophysiological alterations,multimodal imaging features and possible pathogenesis of pachychoroid disease spectrum. (bvsalud.org)
Notably, KEGG pathway analysis suggested that 'Alzheimer's disease' and 'oxidative phosphorylation' pathways may be impaired in PSD pathogenesis, while ZBPYR could play a neuroprotective role through regulating the above pathways. (aging-us.com)

Up to 90% of choroid plexus tumors in children are papillomas, and up to 70% of all choroid plexus papillomas occur in children younger than 2 years. (medscape.com)
Toxoplasma gondii infection, the cause of this disease, may also occur during pregnancy during childhood or in adulthood. (biomedcentral.com)

Its prevalence appears to be quite variable in different countries, but estimates suggest that from 0.3 to 1 % of Europeans and North Americans develop this disease within 1-2 years of contracting the infection [ 9 , 11 , 12 ]. (biomedcentral.com)
A study in the State of Rio Grande do Sul revealed a prevalence of ocular toxoplasmosis of 21.3 % in over 13-year-old individuals and concluded that the disease is a consequence of postnatal infection [ 10 ]. (biomedcentral.com)
For this purpose, we used a mammalian infection model, the ferret, in which NiV causes fulminating systemic disease, with fever and neurologic and/or respiratory signs, similar to those in humans ( 15 ). (cdc.gov)

12 disease terms (MeSH) has been reported with POLR2B gene. (cdc.gov)

Anatomy7

Diseases6

Idiopathic central serous chorioretinopathy. (1/183)

The pathogenesis of choroidal neovascularization in patients with age-related macular degeneration. (2/183)

Autosomal dominant macular atrophy at 6q14 excludes CORD7 and MCDR1/PBCRA loci. (3/183)

Fluorescein angiographic features of choroidal insufficiency in anterior ischemic optic neuropathy. (4/183)

Bullous variant of idiopathic central serous chorioretinopathy. (5/183)

CT-revealed choroidal effusions as a sign of carotid cavernous fistula. (6/183)

Choroidal thickness changes during altered eye growth and refractive state in a primate. (7/183)

Early treatment with cyclosporin in serpiginous choroidopathy maintains remission and good visual outcome. (8/183)

Choroid Diseases

Choroid Plexus

Choroid

Choroid Plexus Neoplasms

Papilloma, Choroid Plexus

Choroid Neoplasms

Cerebral Ventricle Neoplasms

Cerebrospinal Fluid

Uvea

Ependyma

Pigment Epithelium of Eye

Sclera

Gyrate Atrophy

Idiopathic central serous chorioretinopathy. (1/183)

The pathogenesis of choroidal neovascularization in patients with age-related macular degeneration. (2/183)

Autosomal dominant macular atrophy at 6q14 excludes CORD7 and MCDR1/PBCRA loci. (3/183)

Fluorescein angiographic features of choroidal insufficiency in anterior ischemic optic neuropathy. (4/183)

Bullous variant of idiopathic central serous chorioretinopathy. (5/183)

CT-revealed choroidal effusions as a sign of carotid cavernous fistula. (6/183)

Choroidal thickness changes during altered eye growth and refractive state in a primate. (7/183)

Early treatment with cyclosporin in serpiginous choroidopathy maintains remission and good visual outcome. (8/183)

Choroidal dystrophies. Causes, symptoms, treatment Choroidal dystrophies

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