Choroid Plexus
Choroid
Choroid Plexus Neoplasms
Benign or malignant tumors which arise from the choroid plexus of the ventricles of the brain. Papillomas (see PAPILLOMA, CHOROID PLEXUS) and carcinomas are the most common histologic subtypes, and tend to seed throughout the ventricular and subarachnoid spaces. Clinical features include headaches, ataxia and alterations of consciousness, primarily resulting from associated HYDROCEPHALUS. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2072; J Neurosurg 1998 Mar;88(3):521-8)
Papilloma, Choroid Plexus
A usually benign neoplasm that arises from the cuboidal epithelium of the choroid plexus and takes the form of an enlarged CHOROID PLEXUS, which may be associated with oversecretion of CSF. The tumor usually presents in the first decade of life with signs of increased intracranial pressure including HEADACHES; ATAXIA; DIPLOPIA; and alterations of mental status. In children it is most common in the lateral ventricles and in adults it tends to arise in the fourth ventricle. Malignant transformation to choroid plexus carcinomas may rarely occur. (Adams et al., Principles of Neurology, 6th ed, p667; DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2072)
Choroid Neoplasms
Choroid Diseases
Cerebral Ventricle Neoplasms
Neoplasms located in the brain ventricles, including the two lateral, the third, and the fourth ventricle. Ventricular tumors may be primary (e.g., CHOROID PLEXUS NEOPLASMS and GLIOMA, SUBEPENDYMAL), metastasize from distant organs, or occur as extensions of locally invasive tumors from adjacent brain structures.
Cerebrospinal Fluid
Uvea
Ependyma
Pigment Epithelium of Eye
Sclera
The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)
Gyrate Atrophy
Ornithine-Oxo-Acid Transaminase
Eye
Meninges
Ciliary Body
Retina
The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.
Blood-Brain Barrier
Retinal Pigment Epithelium
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
Cysts
Fluorescein Angiography
Prealbumin
Choroidal Neovascularization
Cerebral Ventricles
Hydrocephalus
Ependymoma
Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)
Brain Diseases
Iris
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Fundus Oculi
Vitreous Body
Fourth Ventricle
An irregularly shaped cavity in the RHOMBENCEPHALON, located between the MEDULLA OBLONGATA; the PONS; and the isthmus in front, and the CEREBELLUM behind. It is continuous with the central canal of the cord below and with the CEREBRAL AQUEDUCT above, and through its lateral and median apertures it communicates with the SUBARACHNOID SPACE.
Lateral Ventricles
Cavity in each of the CEREBRAL HEMISPHERES derived from the cavity of the embryonic NEURAL TUBE. They are separated from each other by the SEPTUM PELLUCIDUM, and each communicates with the THIRD VENTRICLE by the foramen of Monro, through which also the choroid plexuses (CHOROID PLEXUS) of the lateral ventricles become continuous with that of the third ventricle.
Epithelium
Retinal Detachment
Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).
Arachnoid
Sturge-Weber Syndrome
A non-inherited congenital condition with vascular and neurological abnormalities. It is characterized by facial vascular nevi (PORT-WINE STAIN), and capillary angiomatosis of intracranial membranes (MENINGES; CHOROID). Neurological features include EPILEPSY; cognitive deficits; GLAUCOMA; and visual defects.
Macular Degeneration
Ganglia, Parasympathetic
Coloboma
Immunohistochemistry
Fluorescein
Visna-maedi virus
A species of LENTIVIRUS, subgenus ovine-caprine lentiviruses (LENTIVIRUSES, OVINE-CAPRINE), that can cause chronic pneumonia (maedi), mastitis, arthritis, and encephalomyelitis (visna) in sheep. Maedi is a progressive pneumonia of sheep which is similar to but not the same as jaagsiekte (PULMONARY ADENOMATOSIS, OVINE). Visna is a demyelinating leukoencephalomyelitis of sheep which is similar to but not the same as SCRAPIE.
Indocyanine Green
Fetal Diseases
Corrosion Casting
A tissue preparation technique that involves the injecting of plastic (acrylates) into blood vessels or other hollow viscera and treating the tissue with a caustic substance. This results in a negative copy or a solid replica of the enclosed space of the tissue that is ready for viewing under a scanning electron microscope.
Myopia
A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.
Encyclopedias as Topic
MedlinePlus
Microvascular loops and networks as prognostic indicators in choroidal and ciliary body melanomas. (1/1300)
BACKGROUND: Malignant melanoma of the ciliary body and choroid of the eye is a tumor that disseminates frequently, and 50% of the diagnosed patients die within 10 years. We investigated the hypothesis that, by histopathologic analysis of the arrangement of microvessels (i.e., small blood vessels) in loops and networks, we might be able to differentiate better those patients with a favorable prognosis from those with a poor prognosis. METHODS: We conducted a population-based, retrospective cohort study of melanoma-specific and all-cause mortality for 167 consecutive patients who had an eye surgically removed because of malignant choroidal or ciliary body melanoma during the period from 1972 through 1981. Microvascular loops and networks were evaluated independently by two pathologists who were unaware of patient outcome. RESULTS: Microvascular patterns could be assessed in 134 (80%) of 167 melanoma specimens. The 10-year probability of melanoma-specific survival was worse if microvascular loops (0.45 versus 0.83; two-sided P<.0001) and networks (0.41 versus 0.72, two-sided P<.0001) were present. In multivariate Cox regression analysis of melanoma-specific survival, the hazard ratios were 1.66 (95% confidence interval [CI] = 1.19-2.30) for the presence of loops and networks as a combined three-category variable, 2.36 (95% CI = 1.37-4.05) for the presence of epithelioid cells, 1.11 (95% CI = 1.03-1.19) for the largest basal tumor diameter (evaluated as a continuous variable), and 2.14 (95% CI = 1.25-3.67) for ciliary body involvement. CONCLUSIONS: Patients with malignant uveal melanoma who have a favorable prognosis can be distinguished from those with a poor prognosis by histopathologic analysis of microvascular patterns in uveal melanoma tumor specimens. (+info)Increase in the advanced glycation end product pentosidine in Bruch's membrane with age. (2/1300)
PURPOSE: To determine whether there is an age-related increase of pentosidine in human Bruch's membranes and to localize pentosidine and carboxymethyllysine (CML), two well-characterized, advanced glycation end products (AGEs) in aged human Bruch's membranes and choroid in vivo. METHODS: Human Bruch's membrane samples were isolated from the retinal pigment epithelium (RPE) and choroid and subjected to reversed-phase high-performance liquid chromatography to determine pentosidine content. A polyclonal anti-pentosidine antibody and a monoclonal antibody specific for carboxymethyllysine were used to localize AGEs in 20-month-old nondiabetic, 82-year-old nondiabetic, and 82-year-old diabetic globes. RESULTS: Human Bruch's membranes (n = 20) showed a linear age-dependent increase in pentosidine that reached approximately 0.17 millimoles pentosidine per mole hydroxyproline in late life (r = 0.896; P < 0.001). Immunohistochemical evaluation showed evidence of pentosidine in Bruch's membrane, choroidal extracellular matrix, and vessel walls in the 82-year-old nondiabetic and diabetic globes. A similar staining pattern was found with the anti-CML antibody. Basal laminar deposits and drusen stained with both antibodies in the elderly nondiabetic eye. In contrast, neither antibody stained the 20-month-old tissue. CONCLUSIONS: We provide biochemical and immunohistochemical evidence for the formation of pentosidine and CML structures in human Bruch's membrane and choroid with age. These changes could promote aging of the RPE-Bruch's membrane-choroid complex. (+info)Idiopathic central serous chorioretinopathy. (3/1300)
Idiopathic central serous chorioretinopathy (ICSC) is usually seen in young males with Type A personality. Clinical evaluation of the macula with fundoscopy and biomicroscopy, coupled with fluorescein angiography establishes the diagnosis. Indocyanine green angiographic studies have reinformed that the basic pathology lies in choriocapillaries and retinal pigment epithelium. Most of the ICSC resolve completely in four months, and some of them could resolve early with direct photocoagulation of the leaking site. Oral steroids have no role, and could even cause an adverse reaction. (+info)Clinical characteristics of CHARGE syndrome. (4/1300)
CHARGE syndrome, first described by Pagon, was named for its six major clinical features. They are: coloboma of the eye, heart defects, atresia of the choanae, retarded growth and development including CNS anomalies, genital hypoplasia and/or urinary tract anomalies, and ear anomalies and/or hearing loss. We experienced three cases of CHARGE syndrome who displayed ocular coloboma, heart defects, retarded growth and development, and external ear anomalies, and we also review the previously reported literature concerning CHARGE syndrome. (+info)Effects of bicarbonate ion on chick retinal pigment epithelium: membrane potentials and light-evoked responses. (5/1300)
The purpose of this study was to determine how changes in [HCO3-] alter the electrical properties of the retinal pigment epithelium (RPE). Experiments were conducted on the isolated chick retina-RPE-choroid preparation. The chamber holding the preparation allowed independent perfusion of the retinal and the choroidal surfaces. The light-evoked trans-tissue potential (TTP), the trans-epithelial potential (TEP), the trans-retinal potentials, and the intracellularly-recorded apical and basal membrane potentials were studied. Increasing the [HCO3-]0 in the choroidal bath from 25 to 40 mEq/1 led to an increase in the TTP and TEP. The same change in the retinal bath decreased the TTP because of a biphasic change of the RPE membrane potentials. There was also an increase in the amplitudes of the TEP, the c-wave and the slow PIII. The light-evoked subretinal K+ decrease was greater which is consistent with an increase in the photoreceptor light response. These observations indicated that the decrease of TTP resulted from a basal membrane hyperpolarization followed by an apical membrane depolarization induced by an increase in retinal [HCO3-]0. The relationship of these potential changes to the human bicarbonate responses is discussed. (+info)Dendritic cells and macrophages in the uveal tract of the normal mouse eye. (6/1300)
BACKGROUND/AIMS: Dendritic cells (DC) and macrophages are components of the immune cell populations in the uveal tract whose density, distribution, turnover, and function may play a role in the maintenance of immunological homeostasis in the eye. Little is known of these cells in the mouse eye despite this being the predominant experimental model in many studies of ocular immune responses and immunoinflammatory mediated eye diseases. The aim of the present study was to obtain further immunophenotypic data on resident tissue macrophages and DC populations in the mouse uveal tract. METHODS: Pieces of iris, ciliary body, and choroid dissected from perfusion fixed BALB/c mice were incubated whole in a variety of anti-macrophage and DC monoclonal antibodies (mAbs). Labelled cells were visualised using either single or double immunoperoxidase techniques. RESULTS: Quantitative analysis and double immunolabelling revealed that 80% of F4/80(+) cells (a mAb that recognises both DC and macrophages) in the iris are macrophages (SER4(+)). The iris contained a network of Ia+ cells (412 (SD 130) cells/mm2) of which two thirds appear to be DC. A similar pattern was observed in the ciliary body and choroid. Only a few DC in the uveal tract were very weakly reactive for mAbs which recognise B7-1 (CD80), B7-2 (CD86), beta2 integrin (mAb N418), and multivesicular bodies associated with antigen presentation (mAb M342). CONCLUSIONS: The present study reveals that the mouse uveal tract, like the rat, contains rich networks of DC and resident tissue macrophages. The networks of resident tissue macrophages in the mouse uveal tract closely resemble similar networks in non-ocular tissues. The phenotype of uveal tract DC suggests they are in the "immature" phase of their life cycle, similar to Langerhans cells of the skin, thus implying their role in situ within the eye is antigen capture and not antigen presentation. (+info)Zinc deficiency and oxidative stress in the retina of pigmented rats. (7/1300)
PURPOSE: To determine the effect of moderate zinc deficiency on antioxidant defenses and measures of oxidative stress in the retina and retinal pigment epithelium (RPE) of Brown Norway Rats. METHODS: Twenty-four rats were housed individually and divided into three groups of 8 rats each. Group 1 was fed ad libitum a semipurified control diet formulated to contain 50 parts per million [ppm] total zinc; group 2 was fed ad libitum an identical diet but containing 5 ppm total zinc; and group 3 was pair-fed the control diet but restricted in amount to that consumed by group 2. Food intake was measured daily and the rats weighed weekly. After 6 weeks, the rats were killed and the following measurements were made: serum zinc, serum alkaline phosphatase, retinal zinc, RPE-choroid zinc, RPE-choroid catalase, liver metallothionein (MT), retinal MT, RPE-choroid MT, retinal catalase, and retinal thiobarbituric reactive substances (TBARS). RESULTS: The following showed statistically significant differences between groups 2 and 3, respectively: serum Zn (1216 micro/l versus 1555 microg/l, P < or = 0.01), serum alkaline phosphatase (3.75 U/mg versus 5.10 U/mg, P < or = 0.05), liver MT (4.3 microg/mg protein versus 16.7 microg/mg, P < or = 0.0001), RPE-choroid MT (1.3 microg/mg protein versus 2.2 microg/mg, P < or = 0.02), retinal MT (0.85 microg/mg protein versus 2.8 microg/mg, P < or = 0.05), and retinal TBARS (6.2 nM/mg protein versus 2.2 nM/mg, P < or = 0.05). CONCLUSIONS: The results show that retinal MT and RPE MT concentrations are very sensitive to intake of dietary zinc. The increase in retinal TBARS in group 2 indicates that moderate zinc deficiency increases oxidative stress to the retina. The results also suggest that MT is protective against lipid peroxidation of retinal membranes. (+info)Structural specializations of the eye in the vizcacha (Lagostomus maximus maximus). (8/1300)
Vizcachas (Lagostomus maximus maximus, Chinchillidae) are nocturnal rodents living in burrows in many regions of Argentina, Bolivia, and Chile. We have studied the eye of the vizcacha using several light and electron microscopic procedures, with the purpose of understanding the role of vision in the behavior of this species. Our observations demonstrated an avascular, rod-rich retina, with a specialized region spanning through most of the equator of the eye. In this central band, all neural retinal layers exhibited a high cell density, whereas the photoreceptor layer was characterized by the presence of very long rods. In addition, the central region was associated with a distinct pigmentation pattern, including scarce granulation of the pigment epithelium, low pigmentation of the choroid, and the selective attachment of suprachoroidal cells to the inner scleral surface. These central modifications probably form the structural basis of a reflecting tapetum. The eye of the vizcacha received both long and short ciliary vessels, and a specialized cilio-sclero-choroidal vascular network appeared at the equatorial region. Our findings suggest that the equatorial region of the eye of the vizcacha could be a highly sensitive light detector related to foraging behaviors during crepuscular or nocturnal hours. (+info)
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Peripapillary Choroidal Thickness and Choroidal Area in Glaucoma, Ocular Hypertension and Healthy Subjects by SD-OCT. - PubMed...
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Thy-1 - Webvision
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Superior medullary velum
1. Posterior medullary velum 2. Choroid plexus 3. Cisterna cerebellomedullaris of subarachnoid cavity 4. Central canal 5. ...
List of OMIM disorder codes
PRPH2 Choroid plexus papilloma; 260500; TP53 Choroideremia; 303100; CHM Chromosome 22q13.3 deletion syndrome; 606232; SHANK3 ... HOXA13 Gyrate atrophy of choroid and retina with or without ornithinemia; 258870; OAT Haddad syndrome; 209880; ASCL1 Hailey- ...
Glymphatic system
The majority of the CSF is formed in the choroid plexus and flows through the brain along a distinct pathway: moving through ... Cserr HF (April 1971). "Physiology of the choroid plexus". Physiological Reviews. 51 (2): 273-311. doi:10.1152/physrev.1971.51. ... which is expressed by specialized epithelial cells of the choroid plexus, and aquaporin-4 (AQP4), which is expressed by ...
Santosh G. Honavar
"Extramedullary plasmacytoma confined to the choroid". Am J Ophthalmol. 131 (2): 277-8. doi:10.1016/s0002-9394(00)00706-6. PMID ...
CII protein
Weiter JJ, Roh S (December 1992). "Viral infections of the choroid and retina". Infectious Disease Clinics of North America. 6 ...
Lateral ventricles
This area is referred to as the atrium of the lateral ventricle, and is where the choroid plexus is enlarged as the choroid ... Calcification of the choroid plexus can occur, usually in the atrium. Position of lateral ventricles (shown in red). Drawing of ... Were it not for the choroid plexus, a cleft-like opening would be all that lay between the lateral ventricle and the thalamus; ... The stria terminalis forms the remainder of the roof, which is much narrower than at the body - the choroid plexus moves to the ...
Karl Wilhelm Ludwig Bruch
"Bruch's membrane": Innermost layer of the choroid. Bibliotheca zoologica Verzeichnis der Schriften über Zoologie ..., Volume 1 ...
Ornithine aminotransferase
"Gyrate atrophy of the choroid and retina". National Institutes of Health. Retrieved 2012-08-23. Kim SJ, Lim DH, Kim JH, Kang SW ... The mechanism of gyrate atrophy of choroid and retina is thought to involve the toxicity of glyoxylate. Glutamate-5- ... Deficiency of OAT activities causes ornithine aminotransferase deficiency, also known as gyrate atrophy of choroid and retina. ... "OAT mutations and clinical features in two Japanese brothers with gyrate atrophy of the choroid and retina". Doc Ophthalmol. ...
Ciliary muscle
The arteries of the choroid and iris. The greater part of the sclera has been removed. Iris, front view. Accommodation reflex ... The ciliary muscle develops from mesenchyme within the choroid and is considered a cranial neural crest derivative. The ciliary ...
Lhermitte-Duclos disease
Choroid plexus. *Choroid plexus tumor *Choroid plexus papilloma. *Choroid plexus carcinoma. Multiple/unknown. *Oligoastrocytoma ...
Neuroblastoma
Choroid plexus. *Choroid plexus tumor *Choroid plexus papilloma. *Choroid plexus carcinoma. Multiple/unknown. *Oligoastrocytoma ...
Circulus arteriosus major
It supplies the iris, ciliary body and choroid. The veinous drainage of CIA is : 4 vortex veins that drain into the ophthalmic ...
Ronald Silverman
He also applied this technique to the retina/choroid in the rabbit and demonstrated not only force-induced displacements in ... Effect of ultrasound radiation force on the choroid. Invest Ophthalmol Vis Sci. 2013 Jan 10;54(1):103-9. Official Web Page at ... Effect of ultrasound radiation force on the choroid. Invest Ophthalmol Vis Sci. 2013;54(1):103. Coleman DJ, Lizzi FL, Silverman ...
Kearns-Sayre syndrome
The proposed cause of cerebral folate deficiency in the Kearns-Sayre syndrome is the failure of the mechanisms in the choroid ... Spector R, Johanson CE (2010). "Choroid plexus failure in the Kearns-Sayre syndrome". Cerebrospinal Fluid Res. 7: 14. doi: ...
88Kasyo Junrei
"Katzuya Shimizu (八十八ヶ所巡礼) Guitar講師" [Katzuya Shimizu (88Kasyo Junrei) Guitar Teacher]. Choroidea Music School (in Japanese). ...
Pia mater
The CSF is primarily secreted by the choroid plexus; however, about one-third of the CSF is secreted by pia mater and the other ... A subarachnoid space exists between the arachnoid layer and the pia, into which the choroid plexus releases and maintains the ... The cranial pia mater joins with the ependyma, which lines the cerebral ventricles to form choroid plexuses that produce ... folding inward to create the tela chorioidea of the third ventricle and the choroid plexuses of the lateral and third ...
Bruch's membrane
... is the innermost layer of the choroid. It is also called the vitreous lamina or Membrane vitriae, because of ... The retinal pigment epithelium transports metabolic waste from the photoreceptors across Bruch's membrane to the choroid. ...
Edwards syndrome
2007). "[Choroid plexus cysts and risk of trisomy 18. Modifications regarding maternal age and markers]". Ceska Gynekol (in ... The most common intracranial anomaly is the presence of choroid plexus cysts, which are pockets of fluid on the brain. These ... choroid plexus cysts, underdeveloped thumbs and/or nails, absent radius, webbing of the second and third toes, clubfoot or ...
Cerebrospinal fluid
Most (about two-thirds to 80%) of CSF is produced by the choroid plexus. The choroid plexus is a network of blood vessels ... Unlike blood passing from the capillaries into the choroid plexus, the epithelial cells lining the choroid plexus contain tight ... Choroid plexus of the lateral ventricle produces CSF from the arterial blood provided by the anterior choroidal artery. In the ... A Na-K-Cl cotransporter and Na/K ATPase found on the surface of the choroid endothelium, appears to play a role in regulating ...
Bonnet-Dechaume-Blanc syndrome
Singh, ArunD; Turell, MaryE (2010). "Vascular tumors of the retina and choroid: Diagnosis and treatment". Middle East African ...
Ex vivo
"Choroid Sprouting Assay: An Ex Vivo Model of Microvascular Angiogenesis". PLOS ONE. 8 (7): e69552. Bibcode:2013PLoSO...869552S ...
Citrobacter koseri
... choroid plexus papillomas, craniopharyngiomas, teratomas); even when they present, they are different from the inflammatory ...
Iminoglycinuria
Saito T, Hayasaka S, Yabata K, Omura K, Mizuno K, Tada K (Nov 1981). "Atypical gyrate atrophy of the choroid and retina and ... It is also found in the kidney, optical choroid, and parts of the central nervous system such the brain and microglial cells. ... Saito T, Omura K, Hayasaka S, Nakajima H, Mizuno K, Tada K (Dec 1981). "Hyperornithinemia with gyrate atrophy of the choroid ... Weleber RG, Kennaway NG, Buist NR (Aug 1981). "Gyrate atrophy of the choroid and retina. Approaches to therapy". International ...
Fitxer:Schematic diagram of human eye multilingual.svg - Viquipèdia, l'enciclopèdia lliure
Choroid); 17. Ora serrata, 18. Vitreous humor with 19. Hyaloid canal/(old artery), 20. Retina with 21. Macula or macula lutea, ...
Retinopathy
Non-proliferative retinopathy is often caused by direct damage or remodeling of the small blood vessels supplying the retina.[8] Many common causes of non-proliferative damage include hypertensive retinopathy, retinopathy of prematurity, radiation retinopathy, solar retinopathy, and sickle cell retinopathy. There are three main mechanisms of damage in non-proliferative retinopathy: blood vessel damage or remodeling, direct retinal damage, or occlusion of the blood vessels. The first mechanism is indirect damage by altering the blood vessels that supply the retina. In the case of hypertension, high pressures in the system causes the walls of the artery to thicken, which effectively reduces the amount of blood flow to the retina.[8] This reduction in flow causes tissue ischemia leading to damage. Atherosclerosis, or hardening and narrowing of blood vessels, also reduces flow to the retina. The second mechanism is direct damage to the retina usually caused by free radicals that causes oxidative ...
Central retinal vein occlusion
Disorders of choroid and retina. Hidden categories: *Wikipedia articles needing page number citations from May 2015 ...
Karl Friedrich Canstatt
Über die Krankheiten der Choreida (1837) - On diseases of the choroid. Die Krankheiten des Höheren Alters und Ihre Heilung ( ...
Sperm whale
The choroid is very thick and contains a fibrous tapetum lucidum. Like other toothed whales, the sperm whale can retract and ...
List of -ectomies
Choroidectomy is the removal of the choroid layer of the eye. Clitoridectomy is the partial or total removal of the external ...
Hereditary folate malabsorption
While PCFT is expressed primarily at the basolateral membrane of the choroid plexus, FRα is expressed primarily at the apical ... As indicated above, PCFT is also expressed at the basolateral membrane of ependymal cells of the choroid plexus where it ... FRα-mediated endocytosis which plays an important role in the transport of folates across the choroid plexus into the CSF (see ... "Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma". Nature Communications. 4: 2123. doi: ...
Choroid: MedlinePlus Medical Encyclopedia
choroid - Everything2.com
resembling the chorion; as, the choroid plexuses of the ventricles of the br... ... Cho"roid (?), a. [gr. ; chorion + form.] Anat. resembling the chorion; as, the choroid plexuses of the ventricles of the brain ... Choroid plexus Anat., one of the delicate fringelike processes, consisting almost entirely of blood vessels, which project into ...
Choroid - Eye Muscle Control
Choroid of the eye: MedlinePlus Medical Encyclopedia Image
Choroid Plexus Medical Definition | Merriam-Webster Medical Dictionary
Medical definition of choroid plexus: a highly vascular portion of the pia mater that projects into the ventricles of the brain ... Resources for choroid plexus. Time Traveler: Explore other words from the year choroid plexus first appeared Time Traveler! ... Comments on choroid plexus. What made you want to look up choroid plexus? Please tell us where you read or heard it (including ... Post the Definition of choroid plexus to Facebook Share the Definition of choroid plexus on Twitter ...
Choroid plexus tumours - Canadian Cancer Society
Choroid plexus papillomas are benign, slow-growing tumours. They are usually treated by surgery alone. These types of tumours ... Choroid plexus tumours. Choroid plexus tumours start in the part of the brain called the choroid plexus. The choroid plexus is ... Choroid plexus tumours are graded from I to III.* A grade I tumour is a non-cancerous (benign) tumour. It is called a choroid ... Treatment of choroid plexus tumours. Surgery is the most common treatment used for choroid plexus tumours. Surgery may be the ...
Epithelial choroid layer definition | Drugs.com
Choroid Plexus - MeSH - NCBI
Choroid Plexus Tumors | SpringerLink
Choroid plexus tumors (CPT) are rare tumors of the neuroepithelial tissue of the brain that are most common in young children. ... Choroid plexus Choroid plexus papilloma Atypical choroid plexus papilloma Choroid plexus carcinoma Radiation therapy ... There are three histopathological classifications of choroid plexus tumors: choroid plexus papilloma (CPP), atypical choroid ... Chemotherapy improves the survival of patients with choroid plexus carcinoma: a meta-analysis of individual cases with choroid ...
Choroid plexus - Wikipedia
Choroid Plexus Histology 40x Choroid plexus Choroid plexus Choroid plexus Choroid plexus papilloma Tela choroidea This article ... The choroid plexus or plica choroidea, is a plexus of cells that arises from the tela choroidea in each of the ventricles of ... A choroid plexus is in part of the roof of the fourth ventricle. The choroid plexus consists of a layer of cuboidal epithelial ... The choroid plexus consists of many capillaries, separated from the ventricles by choroid epithelial cells. Fluid filters ...
Choroid glomus - Wikipedia
choroid - Webvision
Tuberculosis of the Choroid: A Further Contribution | The BMJ
Fetal Choroid Plexus Cysts | Mom Answers | BabyCenter
Enlargement of choroid plexus in complex regional pain syndrome | Scientific Reports
Since the choroid plexus can mediate interaction between peripheral and brain inflammation, our findings pinpoint the choroid ... In morphometric brain analysis, we serendipitously found a 21% increase in choroid plexus volume in 12 patients suffering from ... Our findings suggest involvement of the choroid plexus in the pathogenesis of CRPS. ... The choroid plexus, located in brain ventricles, has received surprisingly little attention in clinical neuroscience. ...
Choroid coats - definition of choroid coats by The Free Dictionary
choroid coats synonyms, choroid coats pronunciation, choroid coats translation, English dictionary definition of choroid coats ... choroid. (redirected from choroid coats). Also found in: Thesaurus, Medical, Encyclopedia. cho·roid. (kôr′oid′) or cho·ri·oid ( ... Choroid coats - definition of choroid coats by The Free Dictionary https://www.thefreedictionary.com/choroid+coats ... cho•roid. (ˈkɔr ɔɪd, ˈkoʊr-) adj. 1. Also, cho•roi′dal. like the chorion; membranous. ...
Choroid plexuses - definition of Choroid plexuses by The Free Dictionary
Choroid plexuses synonyms, Choroid plexuses pronunciation, Choroid plexuses translation, English dictionary definition of ... Choroid plexuses. n a multilobed vascular membrane, projecting into the cerebral ventricles, that secretes cerebrospinal fluid ... choroid plexus. (redirected from Choroid plexuses). Also found in: Thesaurus, Medical, Encyclopedia.. Related to Choroid ... Choroid plexuses - definition of Choroid plexuses by The Free Dictionary https://www.thefreedictionary.com/Choroid+plexuses ...
Superior choroid vein | Define Superior choroid vein at Dictionary.com
Choroid plexus of third ventricle definition | Drugs.com
Choroid Plexus Cyst: Causes, Complications, Treatment, and More
Your doctor may find a choroid plexus cyst in your babys brain during a routine prenatal ultrasound. These cysts usually ... Picture of choroid plexus cyst. Share on Pinterest. A choroid plexus cyst, by itself, is a harmless collection of fluid that ... A choroid plexus cyst is a small, fluid-filled space that occurs in a gland in the brain called the choroid plexus. This gland ... Choroid plexus cyst and trisomy 18. Choroid plexus cysts are found in about a third of the time in fetuses with trisomy 18. ...
The Aging of the Choroid | SpringerLink
The choroid is of fundamental importance for nourishment... ... chapter describes the anatomy and the physiology of the choroid ... The choroid is of fundamental importance for nourishment of the retina so that all the alterations of the choroid lead to a ... Age-related changes of choroid are analyzed. Alterations have been described in the various layers of the choroid, which are ... choroid aging age-related macular disease choroidopaty hypertensive choroidopathy This is a preview of subscription content, ...
Imaging in Choroid Plexus Papilloma: Overview, Radiography, Computed Tomography
Choroid plexus papilloma is a rare, slow-growing, histologically benign intracranial neoplasm that is commonly located in the ... encoded search term (Imaging in Choroid Plexus Papilloma) and Imaging in Choroid Plexus Papilloma What to Read Next on Medscape ... The blood supply to choroid plexus papillomas is derived from the choroid plexus. An enlarged anterior choroidal artery ... including choroid plexus papillomas. Choroid plexus papillomas appear as well-marginated round or lobulated solid masses and ...
Pathology of Choroid Plexus Neoplasms: Overview, Etiology, Clinical Features
Choroid plexus tumors are graded based on the World Health Organization (WHO) classification scheme and include choroid plexus ... tumors derived from choroid plexus epithelium that are seen predominantly in children. ... Choroid plexus neoplasms are rare, intraventricular, primary central nervous system (CNS) ... Choroid plexus carcinomas (WHO grade III). Although choroid plexus papillomas typically look similar, one to another, choroid ...
Choroid Plexus Tumors Diagnosis and Treatment - National Cancer Institute
Learn about choroid plexus tumor grades, features, causes, symptoms, who the tumors affect, how and where they form, and ... Where do choroid plexus tumors form?. Choroid plexus tumors arise from a structure in the brain called the choroid plexus. It ... What do choroid plexus tumors look like on an MRI?. Choroid plexus tumors usually appear in the ventricles of the brain. They ... Choroid plexus tumors occur in both children and adults, but are more common in children in the first year of life. Choroid ...
Choroid | Health Encyclopedia | FloridaHealthFinder.gov
Human Choroid Plexus | Nikon's MicroscopyU
The choroid plexus is comprised of a network of minute fringed capillaries, which secrete a liquid that is vital to the health ... Human Choroid Plexus. Human Choroid Plexus. The choroid plexus is comprised of a network of minute fringed capillaries, which ... The blood vessels of the choroid plexus protrude from the delicate envelope that covers the brain surface and continually leak ...
What is a Choroid Plexus Cyst? (with pictures)
A choroid plexus cyst is a sac of fluid that grows in the brain of a fetus as it develops. Though a choroid plexus cyst is not ... Choroid plexus cysts are relatively common. About one percent of fetuses in the second and third trimester have a choroid ... A choroid plexus cyst is a cyst that can grow in the brain of a fetus during development. They are most commonly seen in the ... The choroid plexus of the brain is a small area near the lower middle portion of the organ that produces cerebral spinal fluid ...
Healthboards - Genetics - Down Syndrome: Anyone have choroid plexus
I was wondering how many children had choroid plexus cysts. I was told it could indicate Downs Syndrome and would like to know ... I recently found out that the baby we are expecting has several choroid plexus cysts. We did not have amnio or AFP or triple ... Anyone have choroid plexus cysts? I recently found out that the baby we are expecting has several choroid plexus cysts. We did ... Adult with Choroid Plexus Cysts hoping to talk to others lovemyrinny. Brain & Nervous System Disorders. 12. 06-05-2007 08:39 AM ...
Choroid Plexus Cysts found on baby in ultrasound | Mom Answers | BabyCenter
Dilated kidney...and choroid plexus cysts - Pregnancy: Ages 25-34 - MedHelp
I had my anatomy scan and doctor said he saw a choroid plexus cyst and dilated kidney. Said both are common I am just curious ... Dilated kidney...and choroid plexus cysts. Anyone else been told that their baby boy has a dilated kidney? I had my anatomy ... Anyone else been told that their baby boy has a dilated kidney? I had my anatomy scan and doctor said he saw a choroid plexus ... scan and doctor said he saw a choroid plexus cyst and dilated kidney. Said both are common I am just curious if any of your ...
CerebrospinalCystEpitheliumCarcinomaIncluding choroid plexusTumorRetina and choroidExpressed in the choroid plexusHydrocephalusEpithelialCarcinomasAtypicalVascularRemoval of the choroid plexusClosure of the choroid fissureTela choroideaFetal choroid plexuBilateral choroid plexuCalled the choroid plexusBenign choroid plexus papillomasAssociation between choroid plexuTrisomy 18Disseminated choroid plexus paPlexusesMalignantPorcine choroid plexusAtrophyBlood-CSF barrierChildren with choroidTissueEpendymal cellsFourth ventricleCiliaryNeoplasmsCauses choroidFissure closureMelanomaProducesVentricles of the brainChoroidalUltrasoundPrognosisLining of the retinaClinical
Cerebrospinal19
- The choroid plexus produces most of the cerebrospinal fluid (CSF) of the central nervous system. (wikipedia.org)
- The choroid plexus regulates the production and composition of cerebrospinal fluid (CSF), that provides the protective buoyancy for the brain. (wikipedia.org)
- The choroid plexus is a small organ in the ventricles of the brain that makes cerebrospinal fluid (CSF). (cancer.ca)
- In children, choroid plexus papillomas can be heterogeneous in appearance because of the accumulation of cerebrospinal fluid (CSF), blood, and blood products between the fronds and papillae. (medscape.com)
- Choroid plexus neoplasms can produce hydrocephalus and increased intracranial pressure by a number of mechanisms, including obstruction of normal cerebrospinal fluid (CSF) flow, overproduction of CSF by the tumor itself, local expansion of the ventricles, or spontaneous hemorrhage. (medscape.com)
- Cerebrospinal fluid overproduction and hydrocephalus associated with choroid plexus papilloma. (nih.gov)
- Choroid plexus produces cerebrospinal fluid and is seen prominently in the posterior horn of the lateral ventricle in second-trimester ultrasounds. (jabfm.org)
- In the 9th week of gestational age, the choroid plexus begins producing cerebrospinal fluid leading to expansion of the ventricular system. (jabfm.org)
- Os pesquisadores encontraram que o plexo choroid actua como meio uma "rede de pesca" essa captações a proteína, chamou o beta-amyloid, e impede que se acumule no líquido cerebrospinal, que cerca e banha o cérebro e a medula espinal. (news-medical.net)
- A pesquisa focalizou em como o plexo choroid funciona para limpar o beta-amyloid do líquido cerebrospinal. (news-medical.net)
- Estes resultados parecem dizer-nos que que um plexo choroid saudável pode remover o beta-amyloid do líquido cerebrospinal, sugerindo um caminho novo para que o cérebro mantenha um balanço normal," Zheng disse. (news-medical.net)
- These tumors arise from the choroid plexus, which lines the ventricles of the brain and produces cerebrospinal fluid. (abta.org)
- Cerebrospinal fluid is continuously formed, mainly by secretion through the thin walls of the choroid plexuses. (thefreedictionary.com)
- INTRODUCTION: The removal of the choroid plexus from the lateral ventricles was attempted by Dandy in the early 20th century but later discarded as complications arose and other methods of cerebrospinal fluid (CSF) diversion were introduced. (biomedsearch.com)
- The choroid plexus epithelium constitutes the structural basis of the blood-cerebrospinal fluid barrier. (hindawi.com)
- In the mammalian brain the cerebrospinal fluid (CSF) is produced by the choroid plexus (CP), which not only regulates homeostasis in the central nervous system (CNS), but also participates in neurohumoral brain modulation as well as neuroimmune interaction [ 1 , 2 ]. (hindawi.com)
- Choroid plexus papilloma (CPP) ia a non-cancerous (benign) tumor of the choroid plexus , a network of blood vessels in the brain which surrounds the ventricles and produces the fluid surrounding the brain and spinal cord (cerebrospinal fluid, or CSF). (nih.gov)
- Because the choroid plexus is responsible for the generation of cerebrospinal fluid containing the intact form of prosaposin, the present study raises the possibility that Pro+0 mRNA is related to the intact form in the choroid plexus and that the alternatively spliced forms of mRNAs do not simply correspond to the precursor and intact forms of prosaposin. (springer.com)
- Western blot was also performed in cerebrospinal fluid, serum and choroid plexus using anti-S-100β, antitransthyretin. (scirp.org)
Cyst28
- Choroid plexus cyst- no nipt- panicking! (babycenter.com)
- What Is a Choroid Plexus Cyst? (healthline.com)
- A choroid plexus cyst is a small, fluid-filled space that occurs in a gland in the brain called the choroid plexus. (healthline.com)
- A choroid plexus cyst is found in some fetuses and is usually picked up on an ultrasound during a woman's second trimester of pregnancy. (healthline.com)
- For reasons that aren't fully understood, a choroid plexus cyst can form when fluid becomes trapped within the layers of cells of the choroid plexus. (healthline.com)
- By around 25 weeks, a choroid plexus cyst can be visible on an ultrasound. (healthline.com)
- When seen by itself, with all other systems developing normally, a choroid plexus cyst is what scientists call a normal variant. (healthline.com)
- While many fetuses with trisomy 18 also have choroid cysts, only a small percentage of those with a choroid plexus cyst will also have trisomy 18. (healthline.com)
- A fetus with trisomy 18 will have other abnormalities seen on an ultrasound besides the choroid plexus cyst. (healthline.com)
- What does a choroid plexus cyst look like on an ultrasound? (healthline.com)
- A choroid plexus cyst is an incidental finding discovered during a routine middle-of-pregnancy ultrasound. (healthline.com)
- A choroid plexus cyst, by itself, is a harmless collection of fluid that can sometimes be seen in the choroid plexus portion of the brain. (healthline.com)
- Even when an otherwise healthy child is born with a choroid plexus cyst, the baby will likely develop normally. (healthline.com)
- Need some help understanding what a choroid plexus cyst is. (healthboards.com)
- I had my anatomy scan and doctor said he saw a choroid plexus cyst and dilated kidney. (medhelp.org)
- The first description of choroid plexus cyst (CPC) on antenatal sonogram appeared in the literature in 1984, 1 and soon after its association with trisomy 18 was described. (jabfm.org)
- When a choroid plexus cyst is identified, the presence of structural malformations and other sonographic markers of aneuploidy should be assessed with a detailed fetal anatomic survey performed by an experienced provider. (contemporaryobgyn.net)
- A choroid plexus cyst is a small fluid-filled structure within the choroid of the lateral ventricles of the fetal brain. (contemporaryobgyn.net)
- What are the major clinical implications of an isolated choroid plexus cyst? (contemporaryobgyn.net)
- If no other sonographic abnormalities are present, the choroid plexus cyst is considered isolated. (contemporaryobgyn.net)
- A choroid plexus cyst is not considered a structural or functional brain abnormality. (contemporaryobgyn.net)
- 2 The only association of some significance between an isolated choroid plexus cyst and a possible fetal problem is with trisomy 18. (contemporaryobgyn.net)
- Based on a meta-analysis of 14 studies published before 2000, Ghidini et al suggested utilization of a composite (+) likelihood ratio of 7.09 (95% CI, 3.97-12.18).4 A large, single-center cohort study (N=1111 cases of isolated choroid plexus cyst) published in 2008 reported much lower risk. (contemporaryobgyn.net)
- When an isolated choroid plexus cyst is detected, how is counseling different for women with a normal screen versus those whose screening indicates increased risk? (contemporaryobgyn.net)
- Counseling for a woman after prenatal identification of a fetal choroid plexus cyst should be guided by the presence or absence of other sonographic markers or structural abnormalities, results of maternal screening for risk of trisomy 18 (if performed), and maternal age (Figure 2). (contemporaryobgyn.net)
- In women who screen negative for trisomy 18 (either first- or second-trimester screening) and in whom no other fetal structural abnormalities are visualized on a detailed ultrasound, the finding of an isolated choroid plexus cyst does not require additional genetic testing. (contemporaryobgyn.net)
- I had my 20 week ultrasound and it shows 1 small choroid plexus cyst on baby's brain. (whattoexpect.com)
- A case of symptomatic cyst of the choroid plexus of a lateral ventricle in a child is reported. (ovid.com)
Epithelium8
- The epithelium of the choroid plexus is continuous with the ependymal cell layer (ventricular layer) that lines the ventricular system. (wikipedia.org)
- The choroid is of fundamental importance for nourishment of the retina so that all the alterations of the choroid lead to a disfunction of the retinal pigment epithelium (RPE), Bruch's membrane, and choriocapillary complex. (springer.com)
- Choroid plexus neoplasms are rare, intraventricular, primary central nervous system (CNS) tumors derived from choroid plexus epithelium that are seen predominantly in children. (medscape.com)
- To report the association of angioid streaks in patients with Pseudoxanthoma elasticum (PXE) with reticular pseudodrusen (RPD), thin choroid, and retinal pigment epithelium (RPE) atrophy using swept-source optical coherence tomography (SS-OCT) and short-wave autofluorescence (SWAF). (healio.com)
- Choroid plexus carcinomas (CPCs) are rare, aggressive brain tumors arising from the cerebral ventricular epithelium and comprising 10-20% of intracranial tumors in children less than 1 year of age. (frontiersin.org)
- The consist of fragments of delicate papillary structures with fibrovascular cores covered by a single layer of cytologically unremarkable choroid plexus epithelium. (radiopaedia.org)
- Introduction: Choroid plexus carcinoma (CPC) is a rare central nervous system neoplasm derived from the choroid plexus epithelium. (omicsonline.org)
- Both hindbrain roof plate epithelium (hRPe) and hindbrain choroid plexus epithelium (hCPe) produce morphogens and growth factors essential for proper hindbrain development. (biologists.org)
Carcinoma18
- It is called a choroid plexus carcinoma. (cancer.ca)
- The most common chemotherapy combination used to treat choroid plexus carcinoma is ifosfamide (Ifex), carboplatin (Paraplatin, Paraplatin AQ) and etoposide (Vepesid, VP-16). (cancer.ca)
- There are three histopathological classifications of choroid plexus tumors: choroid plexus papilloma (CPP), atypical choroid plexus papilloma (ACP), and choroid plexus carcinoma (CPC). (springer.com)
- Gross total resection improves overall survival in children with choroid plexus carcinoma. (springer.com)
- Choroid plexus neoplasms: toward a distinction between carcinoma and papilloma using arterial spin-labeling. (springer.com)
- Choroid plexus tumors are graded based on the World Health Organization (WHO) classification scheme and include choroid plexus papilloma (CPP) (WHO grade I) (see the following image), atypical choroid plexus papilloma (WHO grade II), and choroid plexus carcinoma (CPC) (WHO grade III). (medscape.com)
- Grade III choroid plexus carcinoma are malignant (cancerous). (cancer.gov)
- Choroid plexus carcinoma is the malignant (cancerous) form of the choroid plexus papilloma. (abta.org)
- Choroid plexus carcinoma occurs primarily in children. (abta.org)
- Sanford Research scientists are published in Nature Cell Biology for their work developing a model to explore therapies for a pediatric brain tumor known as choroid plexus carcinoma. (medicalxpress.com)
- In January 2011, a 4 month old female presented with increased emesis and a bulging fontanelle and was diagnosed with Choroid Plexus Carcinoma (CPC) in the right ventricle with metastatic tumor cells present in the cerebral spinal fluid (CSF) and leptomeningeal carcinomatosis. (frontiersin.org)
- Choroid plexus carcinoma (CPC) is a rare brain tumor that occurs most commonly in very young children and has a dismal prognosis despite intensive therapy. (aacrjournals.org)
- In rare cases of choroid plexus papilloma or carcinoma, hydrocephalus is due to an overproduction of CSF. (ugent.be)
- Eppinger MA, Berman CM, Halpern SL, Mazzola CA (2016) Prolonged Survival for Choroid Plexus Carcinoma with Oncocytic Changes: A Case Report. (omicsonline.org)
- Choroid plexus carcinoma s ( CPC ) are rare, malignant neoplasms that represent 20-30% of CPTs in children [ 5 ]. (omicsonline.org)
- Pathological and immunohistochemical studies of choroid plexus carcinoma of the dog. (thefreedictionary.com)
- The critical diagnosis of this neoplasm is often difficult because of its similarity with other primary or secondary papillary lesions of the pineal region, including parenchymal pineal tumors, papillary ependymoma, papillary meningioma, choroid plexus papilloma, and metastatic papillary carcinoma. (wikipedia.org)
- however, morphologically the tumors appeared to be less differentiated than a choroid plexus papilloma and more differentiated than a choroid plexus carcinoma. (wikipedia.org)
Including choroid plexus1
- The advent of CT scanning has resulted in improvement in the detection and characterization of all intracranial masses, including choroid plexus papillomas. (medscape.com)
Tumor12
- Choroid plexus tumor epidemiology and outcomes: implications for surgical and radiotherapeutic management. (springer.com)
- Although choroid plexus papillomas are readily apparent on most nonenhanced studies, the omission of enhanced imaging from the imaging protocol may result in incorrect conclusions about the tumor type and extent. (medscape.com)
- In addition, misdiagnosis may result from an attempt to classify a choroid plexus tumor as benign or malignant solely on the basis of imaging characteristics. (medscape.com)
- Choroid plexus papillomas may have limited parenchymal invasion, which makes the distinction of the benign tumor from its malignant counterpart difficult. (medscape.com)
- The most frequent route of choroid plexus tumor spread is via seeding of the CSF. (medscape.com)
- What are the symptoms of a choroid plexus tumor? (cancer.gov)
- To improve choroid plexus tumor treatment through better understanding of the tumor biology and through increased knowledge about the benefit of specific treatment elements. (clinicaltrials.gov)
- To compare the survival times after cyclophosphamide based treatment with the survival times after carboplatin based treatment in choroid plexus tumor patients. (clinicaltrials.gov)
- Choroid plexus papilloma is a rare, benign (noncancerous) tumor. (abta.org)
- Choroid plexus papilloma (CPP) is a rare type of brain tumor. (ahealthyme.com)
- A CPP tumor grows in the choroid plexus. (ahealthyme.com)
- New page: '''Choroid plexus tumor''' is a rare type of cancer that occurs in the choroid plexus of the brain . (wikidoc.org)
Retina and choroid8
- ICD-9 code 239.81 for Neoplasms of unspecified nature, retina and choroid is a medical classification as listed by WHO under the range -NEOPLASMS OF UNSPECIFIED NATURE (239). (aapc.com)
- Edward C. W. Lee, Johannes F. de Boer, Mircea Mujat, Hyungsik Lim, and Seok H. Yun, "In vivo optical frequency domain imaging of human retina and choroid," Opt. (osapublishing.org)
- This study will investigate use of high frequency (20 MHz) ultrasound for imaging of the retina and choroid in patients with age-related macular degeneration, a prime cause of blindness. (clinicaltrials.gov)
- Specifically, high-resolution ultrasound will be used to generate images of the retina and choroid, including perfusion measurements using slow-flow methods developed by our research group. (clinicaltrials.gov)
- This study aimed to evaluate if pDCs are present in naïve retina and choroid. (arvojournals.org)
- Retina and choroid of naïve 6-8 week-old male wild-type C57BL/6 mice were digested via collagenase and DNase. (arvojournals.org)
- The aim of this study was to identify the morphological features of the retina and choroid in Macaca fascicularis of different ages using multimodal imaging. (springer.com)
- The aim of this study is to describe the microstructures of the retina and choroid in Macaca fascicularis and to compare the features of macaque eyes among different age groups. (springer.com)
Expressed in the choroid plexus2
Hydrocephalus1
- Children with choroid plexus tumours commonly have a buildup of CSF (hydrocephalus), which causes increased pressure on the brain and an increase in skull size. (cancer.ca)
Epithelial14
- Unlike the ependyma, the choroid plexus epithelial layer has tight junctions between the cells on the side facing the ventricle (apical surface). (wikipedia.org)
- Choroid plexus epithelial cells actively transport sodium ions into the ventricles and water follows the resulting osmotic gradient. (wikipedia.org)
- The choroid plexus consists of many capillaries, separated from the ventricles by choroid epithelial cells. (wikipedia.org)
- The blood-CSF boundary at the choroid plexus is a membrane composed of epithelial cells and tight junctions that link them. (wikipedia.org)
- By 14 days both dark and light choroid plexus epithelial cells are present. (nih.gov)
- In contrast to the light choroid plexus epithelial cells, the dark cells have fine narrow microvilli. (nih.gov)
- In agreement, expression of the proinflammatory cytokine TNF α is markedly increased in porcine choroid plexus epithelial cells after infection with the gram-positive bacterium Streptococcus suis [ 7 ]. (hindawi.com)
- The choroid plexus (CP) is an epithelial and vascular structure in the ventricular system of the brain that is a critical part of the blood-brain barrier. (sigmaaldrich.com)
- This work is the first to identify the zebrafish choroid plexus and to characterize its epithelial and vasculature integration. (sigmaaldrich.com)
- NBC mRNA and protein were also present in epithelial cells of choroid plexus, ependyma, and meninges. (jneurosci.org)
- The choroid plexus is located within the cerebral ventricles and is made of epithelial cells , loose connective tissue ( tela choroidea ), and permeable capillaries. (radiopaedia.org)
- Choroid plexus tumors (CPTs) are rare, intraventricular neoplasms that originate from the epithelial cells of the choroid plexus [ 1 - 4 ]. (omicsonline.org)
- We used flow cytometry and the UIC2 monoclonal antibody against Pgp, to demonstrate the presence of Pgp in the epithelial cell fraction isolated from the sheep choroid plexuses (CPEC). (nel.edu)
- The choroid plexus (ChP) is a highly vascularized tissue found in the brain ventricles, with an apical epithelial cell layer surrounding fenestrated capillaries. (jci.org)
Carcinomas12
- Recurrent choroid plexus carcinomas are tumours that have come back after treatment. (cancer.ca)
- Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis. (springer.com)
- Irrespective of patient age, choroid plexus papillomas outnumber choroid plexus carcinomas by a 5:1 ratio. (medscape.com)
- Choroid plexus carcinomas are also far more common in the pediatric population, with approximately 80% of choroid plexus carcinomas occurring in children. (medscape.com)
- Although the vast majority of choroid plexus tumors are sporadic, hereditary factors appear to play a role in the development of some choroid plexus papillomas and carcinomas. (medscape.com)
- Choroid plexus carcinomas occasionally arise in association with hereditary cancer predisposition syndromes, including the Li-Fraumeni and rhabdoid predisposition syndromes, with germline mutations of TP53 and hSNF5/INI1/SMARCB1, respectively. (medscape.com)
- Seeding of the CSF may be seen even in benign choroid plexus papillomas, but leptomeningeal dissemination is much more common in choroid plexus carcinomas. (medscape.com)
- Choroid plexus carcinomas may also have some swelling around them, which can be seen during an MRI. (cancer.gov)
- Rarely, certain gene changes that can be passed down through families have been linked to a higher chance of developing choroid plexus carcinomas. (cancer.gov)
- Atypical choroid plexus papillomas are considered grade II, and chroid plexus carcinomas are typically grade III tumors. (abta.org)
- Choroid plexus carcinomas (CPCs) are rare, aggressive pediatric brain tumors with no established curative therapy for relapsed disease, and poor survival rates. (frontiersin.org)
- Typical choroid plexus carcinomas (CPCs) show variable morphology with a syncytial or solid arrangement. (thefreedictionary.com)
Atypical2
- A grade II tumour is called an atypical choroid plexus papilloma. (cancer.ca)
- Grade II atypical choroid plexus papilloma are mid-grade tumors. (cancer.gov)
Vascular5
- the double row of vascular projections from the undersurface of the tela choroidea, where it roofs over the third ventricle. (drugs.com)
- The first section of this chapter describes the anatomy and the physiology of the choroid and the vascular pattern of the choroidal vessels. (springer.com)
- Gyrate atrophy is a rare hereditary disease of the eye's retina (the layer of light-sensitive tissue that lines the inside of the eyeball) and choroid (a vascular layer of tissue behind the retina). (clinicaltrials.gov)
- Corrosion casts of the complete vascular network of the choroid plexus of the lateral ventricle in the cat brain were studied in SEM using the injection-replication method. (biomedsearch.com)
- The vascular organization of the choroid plexus of the lateral ventricle in cat is compared to that of the corresponding plexuses in other mammals. (biomedsearch.com)
Removal of the choroid plexus1
- Historically, patients with CPH were treated by shunt procedures or by microsurgical removal of the choroid plexus, which is associated with a high complication rate. (ugent.be)
Closure of the choroid fissure1
- Retinoic acid receptor (RAR) signaling is required for morphogenesis of the ventral optic cup and closure of the choroid fissure, but the mechanisms by which this pathway regulates ventral eye development remain controversial and poorly understood. (pnas.org)
Tela choroidea1
- The choroid plexus or plica choroidea, is a plexus of cells that arises from the tela choroidea in each of the ventricles of the brain. (wikipedia.org)
Fetal choroid plexu1
- I found out yesterday that my baby has fetal choroid plexus cysts. (babycenter.com)
Bilateral choroid plexu2
Called the choroid plexus3
- Choroid plexus tumours start in the part of the brain called the choroid plexus. (cancer.ca)
- Choroid plexus tumors arise from a structure in the brain called the choroid plexus. (cancer.gov)
- These tumors arise from brain tissue called the "choroid plexus. (abta.org)
Benign choroid plexus papillomas1
- The majority of CPTs are benign choroid plexus papillomas, which exhibit excellent prognosis [ 7 ]. (omicsonline.org)
Association between choroid plexu2
- Research shows that there is an association between choroid plexus cysts and aneuploidy. (jabfm.org)
- Counseling should include a discussion of the association between choroid plexus cysts and trisomy 18, and diagnostic testing should be offered. (contemporaryobgyn.net)
Trisomy 187
- Choroid plexus cysts are found in about a third of the time in fetuses with trisomy 18. (healthline.com)
- 20 ,21 Despite the low incidence, CPC has clinical implications for aneuploidy because of an association of choroid plexus with trisomy 18 2 ,5-12 ,22 and trisomy 21. (jabfm.org)
- 13 Approximately three fourths of abnormal fetal karyotypes associated with choroid plexus cysts are trisomy 18 and one fourth are trisomy 21. (jabfm.org)
- Choroid plexus cysts are present in 30% to 50% of fetuses with trisomy 18. (contemporaryobgyn.net)
- Studies from the 1990s reported that the risk of trisomy 18 with isolated choroid plexus cysts was approximately 1 in 200 to 1 in 400. (contemporaryobgyn.net)
- 7 Given the considerable improvements in imaging technology and aneuploidy screening in recent years, the risk of trisomy 18 in the setting of isolated choroid plexus cysts is now believed to be much lower. (contemporaryobgyn.net)
- Ultrasound characteristics of choroid plexus cysts (size, complexity, laterality, and persistence) should not be used to further modify risk because these factors do not significantly impact the likelihood of trisomy 18. (contemporaryobgyn.net)
Disseminated choroid plexus pa1
- Variations of disseminated choroid plexus papilloma: 2 case reports and a review of the literature. (springer.com)
Plexuses5
- as, the choroid plexuses of the ventricles of the brain, and the choroid coat of the eyeball. (everything2.com)
- At 11 to 14 postmenstrual weeks, the US image of the brain is dominated by the two relatively prominent lateral ventricles, which are filled with the choroid plexuses (FIGORE 3, page 41). (thefreedictionary.com)
- Accumulation of benzylpenicillin in choroid plexuses preloaded with HCO3-, SCN- or benzylpenicillin also was stimulated compared with the accumulation in unpreloaded choroid plexuses. (aspetjournals.org)
- The choroid plexuses also form the blood-CSF barrier alongside arachnoid and arachnoid villi 2 . (radiopaedia.org)
- The objective of the present work was to assess the presence of P-glycoprotein (Pgp), which could be responsible for this transport at the level of the choroid plexuses (CP). (nel.edu)
Malignant1
- Malignant progression in choroid plexus papillomas. (springer.com)
Porcine choroid plexus1
- Borlongan CV, Skinner SJ, Geaney M, Vasconcellos AV, Elliott RB, Emerich DF (2004) Intracerebral transplantation of porcine choroid plexus provides structural and functional neuroprotection in a rodent model of stroke. (springer.com)
Atrophy6
- Gyrate atrophy of the choroid and retina, which is often shortened to gyrate atrophy, is an inherited disorder characterized by progressive vision loss. (medlineplus.gov)
- Gyrate atrophy of the choroid and retina (GA) is a rare autosomal recessive chorioretinal degeneration characterized by myopia, cataract, varying degrees of night blindness, and progressive constriction of visual fields associated with chorioretinal atrophy resulting in blindness. (clinicaltrials.gov)
- ICD-9 code 363.42 for Diffuse secondary atrophy of choroid is a medical classification as listed by WHO under the range -DISORDERS OF THE EYE AND ADNEXA (360-379). (aapc.com)
- Angioid streaks in PXE are associated with RPD, thin choroid, and RPE atrophy. (healio.com)
- Gyrate atrophy of the choroid and retina is an inherited disorder of protein metabolism characterized by progressive vision loss. (nih.gov)
- While most people with gyrate atrophy of the choroid and retina have no symptoms other than vision loss, neonatal hyperammonemia (excess ammonia in the blood in the newborn period), neurological abnormalities, intellectual disability , peripheral nerve problems, and muscle weakness may occur. (nih.gov)
Blood-CSF barrier2
- thus the choroid plexus acts as a blood-CSF barrier. (wikipedia.org)
- Development of the choroid plexus and blood-CSF barrier. (radiopaedia.org)
Children with choroid1
- Many children with choroid plexus tumours are treated in a clinical trial. (cancer.ca)
Tissue5
- The choroid plexus consists of modified ependymal cells surrounding a core of capillaries and loose connective tissue. (wikipedia.org)
- The choroid is the middle layer of the eye that contains blood vessels and connective tissue that supplies nutrients to the inner portion of the eye. (medlineplus.gov)
- Choroid plexus tumors (CPT) are rare tumors of the neuroepithelial tissue of the brain that are most common in young children. (springer.com)
- which is the specialized light-sensitive tissue that lines the back of the eye, and in a nearby tissue layer called the choroid. (medlineplus.gov)
- The choroid plexus is made of connective tissue, blood vessels, and the ependymal cells. (ahealthyme.com)
Ependymal cells1
- Choroid plexus cells are involved with ependymal cells in the production of CSF. (labce.com)
Fourth ventricle2
- A choroid plexus is in part of the roof of the fourth ventricle. (wikipedia.org)
- Suprasellar seeding of a benign choroid plexus papilloma of the fourth ventricle with local recurrence. (springer.com)
Ciliary1
- This parasympathetic ganglion contains 2 distinct types of neurons: choroid neurons, which project to vasculature in the eye's choroid layer and use somatostatin as a co-transmitter with ACh, and ciliary neurons, which innervate the ciliary body and iris and use ACh but no known peptide co-transmitter. (jneurosci.org)
Neoplasms5
- in children (mean age, 5.2 yr), choroid plexus papillomas appear as large tumors and account for 1.5-6.4% of intracranial neoplasms. (medscape.com)
- The overall annual incidence of choroid plexus neoplasms for all ages is 0.3 cases per million. (medscape.com)
- [ 2 , 3 ] In adults, they account for less than 1% of primary intracranial neoplasms, whereas choroid plexus tumors represent up to 5% of pediatric brain tumors, and up to 20% of those arising in children aged 1 year and younger. (medscape.com)
- The vast majority of choroid plexus neoplasms arise within the ventricles. (medscape.com)
- The third ventricle is the least common intraventricular location for choroid plexus neoplasms, irrespective of patient age. (medscape.com)
Causes choroid1
- What causes choroid plexus tumors? (cancer.gov)
Fissure closure2
- Although previous studies have implicated neural crest-derived periocular mesenchyme (POM) as the critical target of RA action in the eye, we show here that RAR signaling regulates choroid fissure closure in zebrafish by acting on both the ventral optic cup and the POM. (pnas.org)
- However, very little is known about the cellular mechanisms that regulate choroid fissure closure. (frontiersin.org)
Melanoma5
- Concerning melanoma of the choroid with report of one case of this character and of another exhibiting a pigmented sarcoma of the choroid early in its development. (pubmedcentralcanada.ca)
- A uveal melanoma that arises from the choroid. (mycancergenome.org)
- There are 2 clinical trials for choroid melanoma, of which 1 is open and 1 is completed or closed. (mycancergenome.org)
- Of the trials that contain choroid melanoma as an inclusion criterion, 1 is phase 1/phase 2 (0 open) and 1 is phase 2 (1 open). (mycancergenome.org)
- Au-011 is the most common intervention in choroid melanoma clinical trials. (mycancergenome.org)
Produces1
- Choroid plexus hyperplasia (CPH) is a distinct clinicopathological entity in which the enlarged choroid plexus produces large amounts of CSF. (ugent.be)
Ventricles of the brain1
- Choroid plexus tumors usually appear in the ventricles of the brain. (cancer.gov)
Choroidal3
- Olver JM (1990) Functional anatomy of the choroidal circulation: methyl methacrylate casting of human choroid. (springer.com)
- This article provides an overview of choroidal pathology and the application of contemporary imaging techniques used to view the choroid in vivo. (aop.org.uk)
- Further, to assess if retinal/choroidal pDCs express Toll-like Receptor (TLR)-7 and TLR-9, GFP + cells were isolated from the choroid and retina, and splenic macrophages were sorted as controls via IF staining with F4/80 (macrophage marker) using flow cytometry. (arvojournals.org)
Ultrasound1
- While optical techniques can reveal much about the structure of the retina, ultrasound allows imaging of the choroid and deeper tissues. (clinicaltrials.gov)
Prognosis3
- What is the prognosis of choroid plexus tumors? (cancer.gov)
- The relative 5-year survival rate for choroid plexus tumors is 63.9% but know that many factors can affect prognosis. (cancer.gov)
- The prognosis for choroid plexus papilloma (CPP) is determined mainly by how completely the lesion is removed during surgery. (nih.gov)
Lining of the retina1
- Chorioretinitis is an inflammation of the choroid, which is a lining of the retina deep in the eye. (uvahealth.com)
Clinical3
- Clinical outcome of adult choroid plexus tumors: retrospective analysis of a single institute. (springer.com)
- TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors. (springer.com)
- The goal of this clinical research study is to compare carboplatin to cyclophosphamide when given with etoposide, vincristine, and radiation therapy in the treatment of choroid plexus tumors. (clinicaltrials.gov)