Choristoma: A mass of histologically normal tissue present in an abnormal location.Amniotic Band Syndrome: A disorder present in the newborn infant in which constriction rings or bands, causing soft tissue depressions, encircle digits, extremities, or limbs and sometimes the neck, thorax, or abdomen. They may be associated with intrauterine amputations.Eye Neoplasms: Tumors or cancer of the EYE.Mouth DiseasesBone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.Advertising as Topic: The act or practice of calling public attention to a product, service, need, etc., especially by paid announcements in newspapers, magazines, on radio, or on television. (Random House Unabridged Dictionary, 2d ed)Polyps: Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.Quercetin: A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.Mice, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.Cranial Sutures: A type of fibrous joint between bones of the head.Hamartoma: A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.Hair Color: Color of hair or fur.Privacy: The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)Confidentiality: The privacy of information and its protection against unauthorized disclosure.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Cornea: The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)Bacteriology: The study of the structure, growth, function, genetics, and reproduction of bacteria, and BACTERIAL INFECTIONS.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.BooksPublishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.MEDLINE: The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).Lynx: A genus in the family FELIDAE comprising felines with long legs, ear tufts, and a short tail.Eye Diseases: Diseases affecting the eye.Ointments: Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.Surgery, Veterinary: A board-certified specialty of VETERINARY MEDICINE, requiring at least four years of special education, training, and practice of veterinary surgery after graduation from veterinary school. In the written, oral, and practical examinations candidates may choose either large or small animal surgery. (From AVMA Directory, 43d ed, p278)Guinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.Lacrimal Apparatus: The tear-forming and tear-conducting system which includes the lacrimal glands, eyelid margins, conjunctival sac, and the tear drainage system.Neuroradiography: Radiography of the central nervous system.Lacrimal Apparatus Diseases: Diseases of the lacrimal apparatus.Conjunctiva: The mucous membrane that covers the posterior surface of the eyelids and the anterior pericorneal surface of the eyeball.Tears: The fluid secreted by the lacrimal glands. This fluid moistens the CONJUNCTIVA and CORNEA.T-Lymphocytes, Regulatory: CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. They inhibit the immune response by influencing the activity of other cell types. Regulatory T-cells include naturally occurring CD4+CD25+ cells, IL-10 secreting Tr1 cells, and Th3 cells.Forkhead Transcription Factors: A subclass of winged helix DNA-binding proteins that share homology with their founding member fork head protein, Drosophila.Disclosure: Revealing of information, by oral or written communication.Truth Disclosure: Truthful revelation of information, specifically when the information disclosed is likely to be psychologically painful ("bad news") to the recipient (e.g., revelation to a patient or a patient's family of the patient's DIAGNOSIS or PROGNOSIS) or embarrassing to the teller (e.g., revelation of medical errors).Interleukin-2 Receptor alpha Subunit: A low affinity interleukin-2 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN to form a high affinity receptor for INTERLEUKIN-2.Gallbladder: A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.Muscle, Smooth: Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.Gallbladder Neoplasms: Tumors or cancer of the gallbladder.Gallbladder Diseases: Diseases of the GALLBLADDER. They generally involve the impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, neoplasms, or other diseases.International Classification of Diseases: A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (From ICD-10, p1). The Clinical Modifications, produced by the UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S.Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Clinical Coding: Process of substituting a symbol or code for a term such as a diagnosis or procedure. (from Slee's Health Care Terms, 3d ed.)Skull: The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.Lipoma: A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.Endometriosis: A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.Radiology: A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease.Radiology Department, Hospital: Hospital department which is responsible for the administration and provision of x-ray diagnostic and therapeutic services.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Newspapers: Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)

Characterization of nodular neuronal heterotopia in children. (1/605)

Neuronal heterotopia are seen in various pathologies and are associated with intractable epilepsy. We examined brain tissue from four children with subcortical or periventricular nodular heterotopia of different aetiologies: one with severe epilepsy following focal brain trauma at 17 weeks gestation, one with hemimegalencephaly and intractable epilepsy, one with focal cortical dysplasia and intractable epilepsy, and one dysmorphic term infant with associated hydrocephalus and polymicrogyria. The connectivity of nodules was investigated using histological and carbocyanine dye (DiI) tracing techniques. DiI crystal placement adjacent to heterotopic nodules revealed numerous DiI-labelled fibres within a 2-3 mm radius of the crystals. Although we observed labelled fibres closely surrounding nodules, the majority did not penetrate them. Placement of DiI crystals within nodules also identified a limited number of projections out of the nodules and in one case there was evidence for connectivity between adjacent nodules. The cellular and neurochemical composition of nodules was also examined using immunohistochemistry for calretinin and neuropeptide Y (NPY), which are normally expressed in GABAergic cortical interneurons. Within heterotopic nodules from all cases, numerous calretinin-positive neurons were identified, along with a few cell bodies and many processes positive for NPY. Calretinin-positive neurons within nodules were less morphologically complex than those in the cortex, which may reflect incomplete differentiation into an inhibitory neuronal phenotype. There were also abnormal clusters of calretinin-positive cells in the overlying cortical plate, indicating that the migratory defect which produces heterotopic nodules also affects development of the cortex itself. Thus, heterotopic nodules consisting of multiple neuronal cell types are associated with malformation in the overlying cortical plate, and have limited connectivity with other brain regions. This abnormal development of connectivity may affect neuronal maturation and consequently the balance of excitation and inhibition in neuronal circuits, leading to their epileptogenic potential.  (+info)

Spatiotemporal pattern of the mouse chondromodulin-I gene expression and its regulatory role in vascular invasion into cartilage during endochondral bone formation. (2/605)

During endochondral bone formation, vascular invasion into cartilage initiates the replacement of cartilage by bone. Chondromodulin-I, a 25 kDa glycoprotein purified from bovine epiphyseal cartilage, was recently identified as a novel endothelial cell growth inhibitor. Here we cloned the mouse chondromodulin-I cDNA from a mouse whole embryo cDNA library. Northern blot analysis revealed that the chondromodulin-I transcripts were expressed in association with the formation of cartilage expressing type II collagen from days 11 to 17 of gestation in mouse embryos, at which time cartilaginous bone rudiments were gradually replaced by bone. Chondromodulin-I mRNA was also detected in the thymus and eyes at a lower level. In situ hybridization revealed significant expression in all cartilaginous tissues in the embryos at days 13.5 and 16 of gestation. However, the expression was completely abolished in the hypertrophic cartilage zone prior to calcification. Upon chondrogenic differentiation of mouse ATDC5 cells in vitro, the expression of chondromodulin-I transcripts was induced concomitantly with the formation of type II collagen-expressing chondrocytes. The expression of the transcripts then declined as type X collagen-expressing hypertrophic chondrocytes appeared in the culture. Purified chondromodulin-I protein inhibited the vascular invasion into cartilage ectopically induced by demineralized bone matrix in nude mice, leading to the suppression of bone formation in vivo. These results suggest that chondromodulin-I is involved in the anti-angiogenic property of cartilage, and that the withdrawal of its expression allows the vascular invasion which triggers the replacement of cartilage by bone during endochondral bone development.  (+info)

Reversion of the differentiated phenotype and maturation block in Sertoli cells in pathological human testis. (3/605)

To study the relationship between abnormal Sertoli cell differentiation and spermatogenic impairment, we examined the expression of Sertoli cell markers normally lost at puberty, cytokeratin 18 (CK18), anti-Mullerian hormone (AMH) and M2A antigen, in three children (aged 1-2 years), 50 adults (aged 19-45 years) with obstructive or non-obstructive azoospermia or oligozoospermia, and six patients (aged 1-18 years) with 5 alpha-reductase deficiency. There was CK18 and/or AMH expression, but never M2A antigen expression, associated with spermatogonial arrest or Sertoli cell-only (SCO) syndrome in infertile men. Loss of M2A antigen suggests the transition of Sertoli cells to an adult phenotype, while CK18 and/or AMH expression may be a manifestation of de-differentiation of Sertoli cells. In 5 alpha-reductase deficiency, there was a sequential loss of CK18, M2A antigen and AMH around puberty, associated with partial spermatogenesis. The persistence of immature Sertoli cells expressing M2A antigen was associated with prepubertal seminiferous cords and SCO syndrome. Therefore, 5 alpha-reductase deficiency may prevent the maturation of Sertoli cells, resulting in impairment of spermatogenesis, and loss of M2A antigen expression coincides with a critical step in the Sertoli cell maturation. High follicle stimulating hormone concentrations due to failure of normal Sertoli cell differentiation indicate a normal development pattern of the hypothalamic-pituitary-gonadal axis.  (+info)

Possible mechanisms by which pro- and prebiotics influence colon carcinogenesis and tumor growth. (4/605)

Oligofructose and inulin, selective fermentable chicory fructans, have been shown to stimulate the growth of bifidobacteria, which are regarded as beneficial strains in the colon. Studies were designed to evaluate inulin (Raftiline) and oligofructose (Raftilose) for their potential inhibitory properties against the development of colonic aberrant crypt foci (ACF) in rats. ACF are putative preneoplastic lesions from which adenomas and carcinomas may develop in the colon. The results of this study indicate that dietary administration of oligofructose and inulin inhibits the development of ACF in the colon, suggesting the potential colon tumor inhibitory properties of chicory fructans. The degree of ACF inhibition was more pronounced in animals given inulin than in those fed oligofructose. Because these prebiotics selectively stimulate the growth of bifidobacteria, ornithine decarboxylase (ODC) activities, ras-p21 ontoprotein expressions and tumor inhibitory activity of lyophilized cultures of Bifidobacterium longum against chemically induced colon and mammary carcinogenesis and against colonic tumor cell proliferation were examined. Dietary administration of lyophilized cultures of B. longum strongly suppressed colon and mammary tumor development and tumor burden. Inhibition of colon carcinogenesis was associated with a decrease in colonic mucosal cell proliferation and activities of colonic mucosal and tumor ornithine decarboxylase and ras-p21. Human clinical trials are likely to broaden our insight into the importance of the pre- and probiotics in health and disease.  (+info)

The effect of synbiotics on colon carcinogenesis in rats. (5/605)

Evidence indicates that consumption of probiotic microorganisms such as bifidobacteria reduces the risk of colon cancer in animal models. Feeding certain fructans such as oligofructose and inulin, which are thought to selectively increase the growth of intestinal bifidobacteria (i.e., a prebiotic effect), also has been shown to reduce colon cancer risk. The objective of our study was twofold, i. e., to determine whether the combination of bifidobacteria and oligofructose would have an additive effect (i.e., synbiotic) in reducing colon cancer risk in rats, and to determine whether other oligosaccharides would also be effective as part of a synbiotic combination. The development of colonic preneoplastic lesions (aberrant crypts) was used as an index of colon cancer risk. In one series of experiments, rats were given the carcinogen 1, 2-dimethylhydrazine (DMH) and administered one of the following treatments: skim milk (control), bifidobacteria (bifido), oligofructose (OF) or bifido + OF. Neither bifido nor OF alone significantly reduced aberrant crypt number. Bifido + OF reduced aberrant crypt number in five of six experiments, although the reduction was significant in only one. However, a paired comparison of the six experiments indicated a significant overall reduction in aberrant crypts by bifido + OF (P = 0.039). Soybean oligosaccharide (SBO) and wheat bran oligosaccharide (WBO) were also fed in combination with bifidobacteria. In two other experiments, SBO did not alter the number of aberrant crypts compared with the control, whereas WBO reduced aberrant crypt number in one experiment but not in another. Of OF, SBO and WBO, only SBO reduced the colonic mucosa proliferation compared with the control. These results suggest that the combination of bifidobacteria and oligofructose reduces colon cancer risk in carcinogen-treated rats, but the effect of other oligosaccharides is uncertain.  (+info)

Adult-onset neurologic dysfunction associated with cortical malformations. (6/605)

BACKGROUND AND PURPOSE: Malformations of cerebral cortical development are common anomalies of the brain, typically causing developmental delay or seizures that are classically thought to begin in childhood. We present clinical and MR imaging data of 16 patients with cortical malformations in whom evidence of neurologic dysfunction was first noted in adulthood, and attempt to determine whether these malformations had any differentiating features from those presenting in childhood. METHODS: Imaging studies and clinical records of 16 patients with adult-onset neurologic dysfunction were reviewed retrospectively. The patients ranged in age from 17 to 64 years (mean age, 35 years) at the time of imaging. Imaging findings were correlated with seizure history. RESULTS: Fourteen patients had subependymal heterotopia (seven women, seven men), and two patients had closed-lip schizencephalies. Eleven patients had epilepsy, with age of onset ranging from 14 to 45 years (mean age, 22 years); four of them were successfully controlled by medication. The remaining five patients had no seizure disorder. All patients, except one, had normal intelligence. The bilaterality or multiplicity of location of heterotopias was not associated with the presence or absence of seizures, seizure frequency, or electroencephalographic results. CONCLUSION: Subependymal heterotopia and small closed-lip schizencephaly may have minor clinical manifestations that are not evident until adulthood, or may, occasionally, never cause neurologic signs or symptoms whatsoever.  (+info)

Pax6 induces ectopic eyes in a vertebrate. (7/605)

We report here that misexpression of the transcription factor Pax6 in the vertebrate Xenopus laevis leads to the formation of differentiated ectopic eyes. Multiple molecular markers indicated the presence of mature lens fiber cells, ganglion cells, Muller cells, photoreceptors and retinal pigment epithelial cells in a spatial arrangement similar to that of endogenous eyes. Lineage tracing experiments showed that lens, retina and retinal pigment epithelium arose as a consequence of the cell-autonomous function of Pax6. These experiments also reveal that the cell autonomous activity of misexpressed Pax6 causes the ectopic expression of a number of genes including Rx, Otx2, Six3 and endogenous Pax6, each of which has been implicated in eye development. The formation of ectopic and endogenous eyes could be suppressed by coexpression of a dominant-negative form of Pax6. These data show that in vertebrates, as in the invertebrate Drosophila melanogaster, Pax6 is both necessary and sufficient to trigger the cascade of events required for eye formation.  (+info)

Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice. (8/605)

A characteristic feature of Alzheimer's disease (AD) is the formation of amyloid plaques in the brain. Although this hallmark pathology has been well described, the biological effects of plaques are poorly understood. To study the effect of amyloid plaques on axons and neuronal connectivity, we have examined the axonal projections from the entorhinal cortex in aged amyloid precursor protein (APP) transgenic mice that exhibit cerebral amyloid deposition in plaques and vessels (APP23 mice). Here we report that entorhinal axons form dystrophic boutons around amyloid plaques in the entorhinal termination zone of the hippocampus. More importantly, entorhinal boutons were found associated with amyloid in ectopic locations within the hippocampus, the thalamus, white matter tracts, as well as surrounding vascular amyloid. Many of these ectopic entorhinal boutons were immunopositive for the growth-associated protein GAP-43 and showed light and electron microscopic characteristics of axonal terminals. Our findings suggest that (1) cerebral amyloid deposition has neurotropic effects and is the main cause of aberrant sprouting in AD brain; (2) the magnitude and significance of sprouting in AD have been underestimated; and (3) cerebral amyloid leads to the disruption of neuronal connectivity which, in turn, may significantly contribute to AD dementia.  (+info)

*Choristoma

... "Choristoma" at Dorland's Medical Dictionary Lee, Kenneth H.; Roland, Peter S. (2013). "Heterotopias, Teratoma, and ... Choristomas, forms of heterotopia, are closely related benign tumors, found in abnormal locations. It is different from ... PMC 5343649 . Goswamy, Monika; Tabasum, Syeda; Kudva, Praveen; Gupta, Shikha (2012). "Osseous choristoma of the periodontium". ... while a choristoma is normal tissue growth in an abnormal location (e.g., gastric tissue located in distal ileum in Meckel ...

*Tongue disease

... for example Leiomyomatous hamartoma Glossoptosis Choristomata - For example, osseous choristoma of the tongue, a very rare ... Fan, SQ; Ou, YM; Liang, QC (Apr 2008). "Glial choristoma of the tongue: report of a case and review of the literature". ... ISBN 0-7216-2921-0. Yaqoob, N; Ahmed, Z; Muzaffar, S (Dec 2002). "Chondroid choristoma of tongue--a rare entity". JPMA. The ... Cartilagenous (chondroid), and glial choristomas may also very rarely occur on the tongue. Lingual thyroid Cleft tongue (bifid ...

*Teratoma

Limbal dermoid is a choristoma, not a teratoma. Teratoma qualifies as a rare disease, but is not extremely rare. Sacrococcygeal ...

*Nasal glial heterotopia

By definition, nasal glial heterotopia is a specific type of choristoma. It is not a teratoma, however, which is a neoplasm ...

*Hamartoma

It is different from choristoma, a closely related form of heterotopia. The two can be differentiated as follows: a hamartoma ... Angiomyolipoma of the kidney was previously considered to be a hamartoma or choristoma. Hamartomas of the spleen are uncommon ... CS1 maint: Multiple names: authors list (link) "Choristoma" at Dorland's Medical Dictionary Lee, Kenneth H.; Roland, Peter S. ( ... PMC 5343649 . Goswamy, Monika; Tabasum, Syeda; Kudva, Praveen; Gupta, Shikha (2012). "Osseous choristoma of the periodontium". ...

*Schimmelpenning syndrome

The major ocular abnormalities are colobomas and choristomas. Skeletal abnormalities may include dental irregularities, ...

*Terminal osseous dysplasia with pigmentary defects

Corneodermatosseous syndrome Osseous choristoma of the tongue List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L ...

*Heterotopia (medicine)

Choristoma West-Eberhard, 2003 Garcia-Bellido Illijin and Illijin, 1930 Levinton, 1988 Sturtevant, 1913; Illijin, 1927; Huxley ...

*Encephalocraniocutaneous lipomatosis

... epibulbar choristoma and other ophtalmic abnormalities. It was named after Haberland and Perou who first described it. Nevus ...

*Eugen Albrecht

He is remembered for development of the concept of "hamartoma and choristoma" in an attempt to describe the relationship ... Hamartoma and Choristoma Google Search published works by Hans Schmaus. Google Search (publications). ...

*Eye neoplasm

Orbital dermoid cysts are benign choristomas which are typically found at the junction of sutures, most commonly at the fronto- ...

*Ectopic salivary gland tissue

... heterotopic or salivary gland choristoma. An accessory salivary gland is ectopic salivary gland tissue with a salivary gland ...

*Ectomesenchymal chondromyxoid tumor

... chondroid choristoma, extraskeletal myxoid chondrosarcoma, focal oral mucinosis, and an ossifying fibromyxoid tumor of soft ...

*Bad breath

... chondroid choristoma and inflammatory myofibroblastic tumor. The lower esophageal sphincter, which is the valve between the ...

*Angiomyolipoma

... or choristoma (benign tumours consisting of normal cells in the wrong location). PEComas are themselves a kind of mesenchymal ...

*Limbal nodule

... a kind of choristoma (NB: in other organs dermoid can refer to a teratoma) malignant melanoma Hampton Roy; Daljit Singh; ...

*List of cutaneous conditions

Nagayama's spots Oral Crohn's disease Oral florid papillomatosis Oral melanosis Osseous choristoma of the tongue Peripheral ...
Nasal glial heterotopia refers to congenital malformations of displaced normal, mature glial tissue, which are no longer in continuity with an intracranial component. This is distinctly different from an encephalocele, which is a herniation of brain tissue and/or leptomeninges, that develops through a defect in the skull, where there is a continuity with the cranial cavity. While nasal glial heterotopia (NGH) is the preferred term, synonyms have included nasal glioma. However, this term is to be discouraged, as it implies a neoplasm or tumor, which it is not. By definition, nasal glial heterotopia is a specific type of choristoma. It is not a teratoma, however, which is a neoplasm comprising all three germ cell layers (ectoderm, endoderm, mesoderm). As a congenital malformation or ectopia, it is distinctly different from the trauma or iatrogenic development of an encephalocele. Patients come to clinical attention early in life (usually at birth or within the first few months), with a firm ...
The development of pancreatic tissue outside the confines of the main gland, without anatomic or vascular connections between them, is a congenital abnormality referred to as heterotopic pancreas. A heterotopic pancreas in the gastrointestinal tract is usually discovered incidentally and the risk of its malignant transformation is extremely low. In this study, we describe the first case of endoepithelial carcinoma arising in a gastric heterotopic pancreas of a 56-year old woman in Greece. She presented with epigastric pain, periodic nausea and vomiting. Esophagogastroduodenoscopy revealed an ulcerated lesion in the gastric antrum, biopsies of which showed intense epithelial dysplasia with incipient malignant degeneration. The pathology report of the distal gastrectomy specimen demonstrated a 2 cm in diameter ulcerative mass in the gastric antrum. Microscopically, an endoepithelial (in situ) carcinoma of the gastric antrum was determined, which in places turned into an microinvasive endomucosal
Ectopic pancreatic tissue, also known as heterotopic pancreatic tissue, refers to the presence of pancreatic tissue in the submucosal, muscularis or subserosal layers of the luminal gastrointestinal tract outside the normal confines of the pancre...
Introduction: Heterotopias, which are also referred to as choristomas and ectopias, are characterized by the presence of normal-appearing tissue in an anatomical location in which they are normally not found. Clinicopathological aspects of Heterotopias of the Head and neck from our institute is presented in this study. Materials and methods: This study is conducted in a tertiary care center for Head and neck diseases. The Heterotopic lesions occurring in head and neck reported between 2008 and 2016 were included in the study. 24 cases of Head and neck heterotopias were identified. Clinical findings, radiological, cytological and histopathological aspects were analysed. Results: Heterotopias constituted 0.17% of all head and neck lesions. A total of 24 cases of heterotopias were analysed. Thyroid heterotopias constituted majority, 13 cases (54.16%). There were 5 cases of Glial heterotopias (20.83%), 3 Salivary gland heterotopias (12.5%), 2 gastric heterotopias (8.33%) (one single tissue type and ...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
췌장과 비장 내 낭성 병변은 방사선학적 영상검사로 진단이 비교적 쉬운 편이나, 췌장 내 부비장에서 발생한 유표피 낭종은 특이적 방사선 소견이 없어 진단하기 매우 어려워 췌장 내 낭성 종양으로 오진되기가 쉽다. 췌장 내 부비장 조직이 상대적으로 많다면, 종괴의 고형 성분이 복부 전산화 단층촬영 검사에서 비장과 비슷한 조영증강을 보이고 자기공명영상 검사에서 비장과 같은 신호 변화를 보인다는 점에서 방사선학적 영상검사로 췌장 내 부비장의 유표피 낭종을 진단 할 수 있다. 하지만 부비장 조직이 많지 않으면 정확한 진단은 매우 힘들며 본 증례에서도 수술 후 절제 조직에서 부비장 조직이 상대적으로 적게 관찰되었으며 이로 인해서 수술 전 영상검사로 정확한 진단은 할 수 없었다. 췌장 내 낭종이 있을 경우 감별진단을 해야 하는 질환으로 ...
In a retrospective study, 37 male and 19 female inbred laboratory mice, from 1 to 36 weeks of age, were diagnosed with lipomatous hamartomas or choristomas from nearly 10,000 mice examined at necropsy over a 24-month period. Hamartomas and choristomas were found to be rare, noninherited tumor-like conditions that occurred spontaneously in 18 inbred strains of mice with a predominance of the conditions in the C3H/HeJ and C57BL/6J strains. Prevalence between strains ranged from 0.6 to 6.2 cases per hundred thousand mice. The 56 cases studied had soft, raised masses that arose on the dorsal midline, primarily above the sutures of the skull. The lesions were prominent on gross examination due to abnormally long hair, change in direction of the hairs, and a change in hair color compared to the normal pelage. Microscopically, the masses consisted of normal adipose tissue in the reticular dermis and subcutis that sometimes extended through the cranial sutures, entering the brain, or expanding
ear a bony deficit with consequent herniation of brain tissue into the middle ear should be ruled out [53]. Three cases of heterotopic brain tissue in the middle ear associated with cholesteatoma have been reported [62]. It is possible that in all three, brain herniation occurred as a result of inflammatory damage to the tegmen tympani. Spontaneous herniations of brain (encephaloceles) may occur into the middle ear through a congenital deficiency of the tegmen or other sites [47].. A case of sebaceous choristoma of the middle ear has been described [82].. Was this article helpful?. ...
Lawson R. Thoracoabdominal duplication cyst containing heterotopic gastric mucosa: report of a case. J Am Osteopath Assoc 1968;67(11):1292. doi: .. Download citation file:. ...
Heterotopic gastric mucosa in the gall bladder is extremely unusual. It was first described by Egyedi in 1934.7 Since then it has been reported in various organs and sites in the gastrointestinal tract, including the tongue,1oesophagus,2 epiglottis,3 small bowel,4 vermiform appendix,5rectum,3 6 and gall bladder.7-17 24-34 A survey of the world literature revealed 45 reports, including the present cases, and interestingly none shared the broad spectrum of clinical and histological findings of our cases.. There is a wide range in patient age, clinical presentation and symptoms, and roentgenographic and pathological findings. From the six extended reviews,6 9 12 15 16 34 it is apparent that the sex distribution is approximately equal with a slight female preponderance, with an age range of 6-77 years (most patients being ⩽30 years). Most patients have upper quadrant abdominal pain, often of a colicky type, or vague discomfort that may be postprandial and accompanied by nausea, vomiting or, in ...
Yang, X.; Guo, K., 2013: Massive lower gastrointestinal bleeding from Meckel's diverticulum with heterotopic pancreas: case report and a brief review of the literature
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TY - JOUR. T1 - Horseshoe shaped ectopic cervical thymus extending into the anterior mediastinum. AU - Cioffi, Ugo. AU - De Simone, Matilde. AU - Nosotti, Mario. AU - Bellaviti, Nadia. AU - Radice, Ferdinando. AU - Santambrogio, Luigi. PY - 2000. Y1 - 2000. UR - http://www.scopus.com/inward/record.url?scp=0034051243&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0034051243&partnerID=8YFLogxK. M3 - Article. C2 - 10890552. AN - SCOPUS:0034051243. VL - 166. SP - 508. EP - 510. JO - European Journal of Surgery, Acta Chirurgica. JF - European Journal of Surgery, Acta Chirurgica. SN - 1102-4151. IS - 6. ER - ...
The 14.5% prevalence of IPs revealed in this study is the highest ever reported as an English full text of a clinical study, to the best of our knowledge. But some studies report prevalences close to this, 10% by Borhan-Manesh et al. [18], 11% by Weickert et al. [27], 12% by Chung et al. [30] using narrow band imaging, 13% by Vesper et al. [33] and 14% by Kumagai et al. [23]. In an abstract, Ohara et al. [52] report even 21%, also using narrow band imaging. The same prevalence of 21% was yielded by an autopsy series of infants and children [53]. In contrast, in the retrospective part of our study, the prevalence was low (0.5%), within the range of previously reported retrospective studies (0.18 to 1.6%) [13, 17, 34-41]. The discrepancy between retrospective and prospective studies is a clear indication that retrospective data comprise endoscopies in which IPs were often overlooked or neglected.. Nevertheless, IP should be looked for, and, if present, mentioned in examination reports. IP may give ...
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It is very unusual of an ectopic thyroid to be presented as a submental swelling, clinically mimicking a submental cyst. Suspicious of the disease with complete clinical, biochemical and radiological...
Mullerianosis is a rare choristoma of Mullerian-derived tissues. It differs from endometriosis in that at least two types of Mullerian-derived tissue is present. The pathogenesis of Mullerianosis is not completely understood, but the majority of...
Aberrations of p53 occur in most, if not all, human cancers. In breast cancer, p53 mutation is the most common genetic defect related to a single gene. Immortalized human mammary epithelial cells resemble the earliest forms of aberrant breast tissue growth but do not express many malignancy-associated phenotypes. We created a model of human mammary epithelial tumorigenesis by infecting hTERT-HME1 immortalized human mammary epithelial cells expressing wild-type p53 with four different mutant p53 constructs to determine the role of p53 mutation on the evolution of tumor phenotypes. We demonstrate that different mutant/wild-type p53 heterozygous models generate loss of function, dominant negative activity, and a spectrum of gain of function activities that induce varying degrees of invasive potential. We suggest that this model can be used to elucidate changes that occur in early stages of human mammary epithelial tumorigenesis. These changes may constitute novel biomarkers or reveal novel ...
A 38-year old woman being investigated for abdominal pain was found to have a small umbilicated lesion in the gastric antrum. Biopsies revealed it to be ectopic pancreatic tissue, a purely coincidental finding ...
Our proposal addresses some of the solutions to the development of complex 3- dimensional tissue models and a new paradigm by using lymph node as in vivo biorea...
Software Packages for Holonomic Gradient Method. The numerical evaluation of the normalizing constant for a given statistical distribution is a fundamental problem in statistics. For example, the normalizing constant of the Gaussian distribution is expressed in terms of a rational expression of a parameter of the distribution named as the standard deviation. However, normalizing constants of many interesting stasistical distributions do not have such closed expressions. The holonomic gradient method, HGM in short, is a general method to evaluate normalizing constant numerically for several parameters in the framework of Zeilbergers holonomic systems approach. In fact, broad classes of normalizing constants are holonomic functions with respect to parameters. Then, such normalizing constants satisfy holonomic systems of linear partial differential equations. The HGM consists of three steps for a given normalizing constant. (1) Find a holonomic system satisfied by the normalizing constant. We may use
Polymicrogyria (PMG) and periventricular nodular heterotopia (PNH) are two developmental brain malformations that have been described independently in multiple syndromes. Clinically, they present with epilepsy and developmental handicaps in both children and adults. Here we describe their occurrence together as the two major findings in a group of at least three cortical malformation syndromes. We identified 30 patients as having both PNH and PMG on brain imaging, reviewed clinical data and brain imaging studies (or neuropathology summary) for all, and performed mutation analysis of FLNA in nine patients. The group was divided into three subtypes based on brain imaging findings. The frontal-perisylvian PNH-PMG subtype included eight patients (seven males and one female) between 2 days and 10 years of age. It was characterized by PNH lining the lateral body and frontal horns of the lateral ventricles and by PMG most severe in the posterior frontal and perisylvian areas, occasionally with ...
PubMedID: 23151899 | Periventricular nodular heterotopia on prenatal ultrasound and magnetic resonance imaging. | Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology | 8/1/2013
CONTEXT: Acute pancreatitis in ectopic pancreatic tissue is an uncommon cause of acute abdominal pain and can be difficult to diagnose on imaging. Our aim is to raise awareness and aid in the diagnosis of this entity by highlighting helpful dynamic contrast-enhanced MRI imaging findings. CASE REPORT: We report a 51-year-old man with acute onset epigastric pain presented to ER. With the presence of elevated serum lipase, the clinical diagnosis of acute pancreatitis was made. Contrast enhanced CT demonstrated normal pancreas and a focal mass at the duodenojejunal flexure, mimicked a neoplasm. Subsequent dynamic contrast enhanced MR images demonstrated enhancement pattern of the lesion similar to the native pancreatic tissue enhancement, a finding raised the possibility of acute pancreatitis in ectopic pancreatic tissue, but tumor was not excluded. Finally, patient undergone surgical bowel resection including the suspected mass that was proved as an ectopic pancreatic tissue on microscopic examination.
The butterfly effect is defined as "the sensitive dependence on initial conditions, where a small change at one place in a deterministic nonlinear system can result in large differences to a later state." In medicine, the identification of a rare disease or a genetic mutation may provide insights that spread well beyond the initial discovery.. And in genetics, scientists are learning just how widespread the effects are for mutations in one gene: filaminA (FLNA).. FLNA is a common cause of periventricular nodular heterotopia (PVNH), a disorder of neuronal migration during brain development. The syndrome was first described by the late Peter Huttenlocher, MD, and the gene was identified by Christopher Walsh, MD, PhD, of Boston Childrens Hospital.. In normal brain development, neurons form in the periventricular region, located around fluid-filled ventricles near the brains center, then migrate outward to form six onion-like layers. In PVNH, some neurons fail to migrate to their proper position ...
Empty right scrotal sac noted. Right testis is superficial to rectus muscle. It is located near lateral margin of right rectus muscle. Cord entering the testis is noted. Right testis is upside down. Right testis is smaller than left. No fo...
OP28 The complement component C3 is expressed by the endometrial ectopic tissue and is involved in the endometriotic lesion formation C. Agostinis 1, G. Zito 1, D. De Santo1, R. Vidergar2, O. Radillo 1, F. Bossi 1, S. Zorzet2, G. Ricci 1, R. Bulla 2 1 Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy 2 Department of Life Sciences, University of Trieste, Trieste, Italy E-mail address: [email protected] (C. Agostinis). Background: The complement (C) system is one of the major components of humoral innate immunity, acting as the first lines of defence against microbes. The principal roles of C system are the opsonization and lysis of pathogens, but new roles in inflammatory and immunological processes are emerging. It is involved in numerous inflammatory diseases, such as SLE, PNH and endometriosis (EM). Several groups have been demonstrated that the glandular epithelial cells found in endometriotic implants produce and secrete the C component C3. The aim ...
CONCLUSIONS: We report the clinical and mutation spectrum as well as MR imaging for a large cohort of 47 patients with Filamin A associated PVNH including two adult males. Our data are reassuring in regard to psychomotor and cognitive development, which is within normal range for the majority of patients. However, a concerning median diagnostic latency of 17 to 20 years was noted between seizure onset and the genetic diagnosis, intensely delaying appropriate medical surveillance for potentially life threatening cardiovascular complications as well as genetic risk assessment and counseling prior to family planning for this X-linked dominant inherited disorder with high perinatal lethality in hemizygous males. ...
Since the observation that malformed brain structure is associated with intractable forms of epilepsy, there has been a great deal of interest in trying to understand the function of dysplastic neurons. Here we performed experiments to investigate the influence of GABAergic inhibition on hippocampal heterotopic neurons in an animal model of malformation-associated epilepsy, e.g., rats exposed to MAM in utero. Our main findings in these animals include the following: (1) an alteration in the decay kinetics of evoked and spontaneous IPSCs recorded on heterotopic neurons, (2) "normal" inhibitory responses for heterotopic neurons after exogenous GABA application, (3) an inability to alter IPSC decay kinetics when heterotopic neurons are exposed to GABA transport inhibitors, and (4) a low level of GAT expression in heterotopic cell regions. Together, these results suggest altered inhibitory synaptic function at heterotopic synapses in the MAM model.. Abnormal electrical discharges, the hallmark of ...
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My 3 yr and 11 month old son just had an MRI for tethered spine. This came up negative but was positive for tonsillar ectopia. He has asthma and is currently taking Nasonex, Albuterol inhaler as needed, and Pulmicort Nebs at night. He also has Dx of ADHD, ODD, and Bi-polar. Can you explain what tonsillar ectopia (mild) is, does it need treatment, what are our treatment options, could any of his mental dxs be from this finding? There isnt much on the internet about this so if you could just expand on this in general, any information would be helpful. Thank you for your time ...
If you are adding the driver to the current insurance then it would cost 300$.It depends on the policies of the insurance companies and it also depends on your state.Same is the case with the California state.The insurance policy in Texas regarding the new driver would be same as above.I hope my answer will help you ...
CORRESPONDENCE. Kebble or quibble?. Dear Aunt Ethel,. To those skilled at matters surgical, a lost orchid is the euphemism for an ectopic testis or undescended testicle. Makes Tretchikoffs originals/collectors pieces sound like priceless balderdash, perhaps?. Yours affectionately. Robert-Ian Caldwell. Hilton, KwaZulu-Natal ...
Dr. Friedlander responded: Not quite, but..... An accessory spleen is something that one person in four is born with, or that can happen if the splenic capsule is torn and some of the pulp is released. If this happened at the time that an injury formed the |a href="/topics/colonic" track_data="{
Question - Face hitting steering wheel. Have seizure like spells, not able to focus. MRI shows heterotopia. Can these be treated with medicine?. Ask a Doctor about when and why MRI is advised, Ask a Neurologist
Aphanitic Singularity [abstrakt Alisa Andrasek + Netochka Nezvanova All possible branches are real (Borges, J.L. The Garden of Forking Paths) Gardens were always optimistic reflections of the world, the liminal spaces between the known and unknown, matter and aether. Foucault describes gardens as the oldest form of heterotopias, a microcosm of species, the smallest parcel of the world in its totality: The heterotopia is capable of juxtaposing in a single real place several spaces, several sites that are in themselves incompatible ... the oldest example of these heterotopias that take the form of contradictory sites is the garden. Shifting away from millennia old, rigid and static instrumentalities of control on the one side and fictional representational effects on the other, this paper discusses genware, a computational system employing dynamically relational assemblages for analysis, synthesis and cataloguing of regional folkloric and cultural artifacts phenotypes into a library of ...
Lesions within Mist1KO pancreatic tissue contain cells that coexpress the Mist1 locus and duct cell markers. (A and B) Immunohistochemistry with CK-20-specifi
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مرحبا بكم في شبكة جامعة بابل الالكترونية لتحميل المحاضرات والبحوث الاكاديمية في موقع الكلية او الاطلاع على لوحة اعلانات الطلاب ونتائج الامتحانات اتبع الروابط في الصفحة الرئيسية لموقع الكلية ضمن شبكة جامعة بابل
A Triad of Congenital Diaphragmatic Hernia, Meckels Diverticulum, and Heterotopic Pancreas. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Periventricular nodular heterotopia (PNH) is a disorder of cortical development [1]. PNH is a term used to describe the collections of neurons lining the lateral ventricles that have failed to migrate normally to form the cerebral cortex [1]. It is a clinically and genetically heterogeneous group of disorders [2]. Mutations in the filamin A gene (FLNA) result in an X-linked dominant form of this disorder [3]. Mutations in FLNA leading to protein truncation are the predominant cause of the PNH phenotype [2, 4]. Most affected females present with seizures and normal to mildly impaired cognitive function [2, 5]. FLNA-associated PNH may also be associated with other cerebral malformations as well as extra-cerebral features [6]. The condition typically results in prenatal lethality or a more severe phenotype in males although paternal transmission has been documented in the literature [2, 7-9].. Mutations in FLNA are associated with a wide spectrum of disorders including the otopalatodigital syndrome ...
Heterotopic pancreas is an uncommon developmental anomaly of upper gastrointestinal tract. Heterotopic pancreas tissue is very rarely found in ileum. Intussusception in children is usually idiopathic, but definitive aetiology can be established in 90% of adult cases. We are reporting a case of pancreatic heterotopia presenting as a lead point of ileo-ileal intussusception in a 1year 3month year old boy.
A nine year old male castrated Siberian Husky presented with a history of cyclic fever, anorexia and lethargy of one year in duration, along with chronic urinary tract infections and urinary incontinence. Initial diagnostics revealed a progressive pneumonia, an intramural ectopic left ureter, and left-sided hydroureter and hydronephrosis. The ectopic ureter was corrected via a ureteral transposition, and the animal recovered well from the procedure. Ectopic ureters are a common cause of urinary incontinence since birth or weaning. They may be unilateral or bilateral, and intramural or extramural. The cause of this abnormality is debated, but it is likely dependant on genetic factors. Ectopic ureters are often associated with other structural or functional abnormalities, which should be identified prior to surgery. Surgical correction may be accomplished via a neoureterostomy and urethral / trigone reconstruction, a ureter transposition, or a nephroureterectomy ...
Ehlers-Danlos syndrome with periventricular heterotopia information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.
Meckels Diverticulum What is Meckels diverticulum? Meckels diverticulum is a small pouch in the wall of the intestine, near the junction of the small and large intestines. The pouch is a remnant of tissue from the prenatal development of the digestive system. It is not made of the same type of tissue as the small intestine, but, instead, is made of the type of tissue found in the stomach or the pancreas. The tissue in Meckels diverticulum produces acid, just as the tissue of the stomach does. The in...
Visualizing the mucosal surface may require using forceps to hold the specimen open (Fig. 19), unlike the specimens pictured in the other gross photographs. Histology shows marked thickening and fibrosis of the lamina propria, submucosa, and muscularis propria (Fig. 20). (Compare the normal histology in Fig. ) Fig. 19 Stricture of the esophagus, fresh specimen 44 Fig. 20 Histology of stricture (H & E, ×20) B. Gorman 2 Histologic Anatomy 45 Inlet Patch The inlet patch is characterized by ectopic gastric mucosa that is surrounded by normal squamous mucosa (Fig. A b Fig. 21 (a) Inlet patch (H & E, ×40). The mucosa on the left side of this photomicrograph shows essentially normal gastric mucosa with foveolar and glandular epithelium. The mucosa on the right shows normal esophageal squamous epithelium. (b) Inlet patch (H & E, ×200). On higher power, the gastric mucosa of the inlet patch is identical to that seen in the stomach, with foveolar epithelium overlying gastric glands composed of mucus ...
A few mutations in the ARFGEF2 gene have been identified in individuals with periventricular heterotopia. These mutations may interfere with vesicle trafficking, which is important in controlling cell migration during the development of the brain. Nerve cells (neurons) that do not migrate properly during development form clumps around fluid-filled cavities (ventricles) near the center of the brain, resulting in the signs and symptoms of periventricular heterotopia.. Mutations in the ARFGEF2 gene may also result in weakening of the attachments (adhesion) between cells that form the lining of the ventricles, by impairing the trafficking of the molecules needed for this adhesion. A weakened ventricular lining could allow some neurons to form clumps around the ventricles while others migrate normally to the exterior of the brain, as seen in periventricular heterotopia. ...
Duplicated Renal Collecting System with Hydronephrosis of the Upper Pole Moiety due to Ectopic Ureter Peer Reviewed Pediatric Radiology Cases
Van Maldergem syndrome is an autosomal recessive disorder characterized by intellectual disability, typical craniofacial features, auditory malformations resulting in hearing loss, and skeletal and limb malformations. Some patients have renal hypoplasia. Brain MRI typically shows periventricular nodular heterotopia (summary by {1:Cappello et al., 2013 ...
Laparoscopic or open resectionof Meckels diverticulum (costs for program #141487) ✔ Academic Hospital Schwabing ✔ Department of Abdominal Surgery ✔ BookingHealth.com
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We read with interest the report by Mitchell et al1 of 4 cases of ectopic posterior pituitary lobe and periventricular heterotopia on MR imaging studies. The authors suggested that ectopic posterior pituitary lobe with growth hormone deficiency is part of a spectrum associated with septo-optic dysplasia and concluded that the coexistence of periventricular heterotopia dysplasia implies a common underlying genetic mechanism. Further, in 1 case, they found the presence of a heterozygous HESX1 mutation, a gene associated with ectopic posterior pituitary lobe and septo-optic dysplasia, and suggested that this gene is important in the development of both ectopic posterior pituitary lobe and periventricular heterotopia.. We report a case of a 4-year-old boy with a history of seizures. The patient had an episode of convulsive seizure in March 2006, with a left focal onset. His medical history included panhypopituitarism and optic atrophy of the right eye. Physical examination was significant for a pale ...
TY - JOUR. T1 - Heterotopic pancreas in omphalomesenteric duct remnant results in persistent umbilical discharge. AU - Park, Eunhyang. AU - Kim, Hyojin. AU - Jung, Whan. AU - Chung, Jin Haeng. PY - 2014. Y1 - 2014. UR - http://www.scopus.com/inward/record.url?scp=84907362254&partnerID=8YFLogxK. U2 - 10.4132/KoreanJPathol.2014.48.4.323. DO - 10.4132/KoreanJPathol.2014.48.4.323. M3 - Article. AN - SCOPUS:84907362254. VL - 48. SP - 323. EP - 326. JO - Korean Journal of Pathology. JF - Korean Journal of Pathology. SN - 1738-1843. IS - 4. ER - ...
TY - JOUR. T1 - Thoracic exploration for mediastinal parathyroids requires a multidisciplinary approach. AU - Mitchell, Jamie C.. AU - Milas, Mira. AU - Berber, Eren. AU - Siperstein, Allan. AU - Shin, Joyce. AU - Rice, Thomas. AU - Mihaljevic, Tomislav. AU - Mason, David. PY - 2012/12/1. Y1 - 2012/12/1. N2 - Mediastinal parathyroid disease requiring a thoracic surgical approach is a rare and challenging clinical entity. The objective of this study was to review our experience treating these patients, highlighting the importance of a multidisciplinary approach. Seven patients required a thoracic approach for mediastinal parathyroid disease between 1999 and 2010. All patients achieved biochemical cure with varying combinations of preoperative and intraoperative localizing studies interpreted by a multidisciplinary team, including radiologists, thoracic and endocrine surgeons, being required in each patient.. AB - Mediastinal parathyroid disease requiring a thoracic surgical approach is a rare and ...
Meckels scan: A Meckels scan involves the administration of 99mtechnetium pertechnetate followed by scintigraphy. The scan identifies areas of gastric mucosa and a will detect a Meckels diverticulum if it has ectopic gastric mucosa.. Approximately half of all Meckels diverticulum do not have gastric mucosa and thus do not cause bleeding and cannot be detected by a Meckels scan. Most are asymptomatic although some can cause recurrent obstruction. A Meckels diverticulum which does not have gastric mucosa may be detected on cross-sectional imaging, although only with a high degree of suspicion. A Meckels diverticulum without gastric mucosa is often an incidental finding at the time of laparotomy, laparoscopy or autopsy.. Laboratory values are significant for a low hemoglobin, which can often be below 8 and is caused by acute hemorrhage. Acute hemorrhage causes vasoconstriction which often decreases the bleeding and helps to stabilize the patient while workup can be performed.. ...
BACKGROUND: Intestinal intussusception is the most frequent cause of small bowel obstruction in children between the ages of 2 months and 5 years and often remains idiopathic in etiology, even after surgery. On microscopic examination, in intussusception normal mucosa is noted but in a few cases heterotopic tissue can be seen. Heterotopic gastric mucosa in the small intestine is extremely rare except for its occurrence in remnants of Meckels diverticulum. In view of the rarity of this condition, we report a case of ectopic gastric mucosa in the small intestine that was not associated with remnants of vitelline duct ...
Schizencephaly (from Greek skhizein, meaning to split, and enkephalos, meaning brain) is a rare birth defect characterized by abnormal clefts lined with grey matter that form the ependyma of the cerebral ventricles to the pia mater. These clefts can occur bilaterally or unilaterally. Common clinical features of this malformation include epilepsy, motor deficits, and psychomotor retardation. Schizencephaly can be distinguished from porencephaly by the fact that in schizencephaly the fluid-filled component, if present, is entirely lined by heterotopic grey matter while a porencephalic cyst is lined mostly by white matter. Individuals with clefts in both hemispheres, or bilateral clefts, are often developmentally delayed and have delayed speech and language skills and corticospinal dysfunction. Individuals with smaller, unilateral clefts (clefts in one hemisphere) may be weak or paralyzed on one side of the body and may have average or near-average intelligence. Patients with schizencephaly may ...
Meckels diverticulum is a small pouch in the wall of the intestine, near the junction of the small and large intestines. The pouch is a remnant of tissue from the prenatal development of the digestive system. It is not made of the same type of tissue as the small intestine, but instead, is made of the type of tissue found in the stomach or the pancreas.. The tissue in Meckels diverticulum can produce acid, just as the tissue of the stomach does. The intestinal lining is sensitive to being in contact with acid, and eventually an ulcer can form. The ulcer can perforate (rupture), causing waste products from the intestine to leak into the abdomen. A serious abdominal infection called peritonitis can result. The intestine can also become obstructed (blocked) by Meckels diverticulum.. ...
Meckels diverticulum - a protrusion in the form of a bag in the terminal ileum. This is inherent in the formation of the small intestine, which can be detected by careful study ...
Fifty-eight human thyroid glands obtained at autopsy from fetuses with proven retrosternal thymus were systematically studied for the presence of intrathyroidal thymic tissue. The latter was found in one thyroid lobe in each of three fetuses (5.1%). It was located in a subcapsular position in two cases (3.4%) and lying deep in thyroid tissue in one (1.7%). Our findings would support a IV-V pharyngeal pouch origin for some accessory thymic tissue and would provide an explanation of the histogenesis of intrathyroid thymomas.
Center for Family Planning and Human Reproduction, Krivoy Rog The main theories of the pathogenesis of endometriosis are described. A modern approach is presented concerning the eutopic endometrium of patients with endometriosis and endometrioid heterotopia, including changes in the expression of inducers of adhesion, invasion, angiogenesis, hormonal inducers, receptivity and inducers of immunity. Differences in healthy endometrium, endometrium of patients with endometriosis and endometrioid heterotopia have been determined. These studies contribute to increasing knowledge of the pathogenesis of endometriosis, the timely identification of possible therapeutic targets and, in addition, realize the effectiveness of methods for early diagnosis and prediction of the course of this pathology. Key words: endometriosis, ectopic endometrium, hormonal inducers, eutopic endometrium, receptivity. REFERENCES 1. Margarit L, Taylor A, Roberts MH, Hopkins L, Davies C, Brenton AG et al. 2010. MUC1 as a ...
Klippel-Feil Syndrome is characterized by congenital fusion of two or more cervical vertebrae. There may be other spinal problems such as spina bifida and scoliosis. Abnormalities of other organs, such as the kidney, heart or lungs can also be present. Features include a short neck, low hairline at the back of the head and restricted mobility of the upper spine.
From the question on page 395 Clinical and CT findings suggested a differential diagnosis between pleural metastasis and splenosis. Histopathology revealed normal splenic tissue, allowing the diagnosis of pleural splenosis.. Thoracic splenosis (TS) is a benign acquired condition involving the autotransplantation of splenic tissue into the pleural cavity. It frequently results from left upper abdominal trauma with concomitant splenic damage and left diaphragmatic tear. Splenic tissue gains access to the left pleural space and derives its blood supply from the pleura, chest wall or diaphragm. TS is usually asymptomatic and found incidentally by imaging examinations performed for other reasons. It rarely causes chest pain or haemoptysis.1-5 The average interval between trauma and TS diagnosis is ∼20 years.. Splenic implants are sessile or pedunculated reddish-blue nodules of normal splenic tissue with diameters ranging from a few millimetres to several centimetres.2 They may occur on the parietal ...
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Results Non-neoplastic acinar cells were stained diffusely, but epithelial cells of the pancreatic duct and the islets of Langerhans were not stained. In pancreatic tumours, all the seven ACCs were diffusely positive for the 2P-1-2-1 antibody. However, no positive staining was found in other pancreatic tumours including NETs, SPNs and ductal adenocarcinomas. The sensitivity and specificity of the 2P-1-2-1 antibody for ACCs were both 100%. In other organs studied, positive staining was observed only in the ectopic pancreas. ...
Meckels diverticulum is a small pouch in the wall of the lower small intestine. The pouch is a congenital (present at birth) abnormality that affects…
Question - Have intrapancreatic cyst. History of epigastric pain. Is this alarming? . Ask a Doctor about diagnosis, treatment and medication for Pancreatitis, Ask a Gastroenterologist
Accessory spleen or splenule is a common congenital anomaly in which an ectopic focus of normal splenic tissue is found separate from the main body of the spleen. They occur in approximately 10% of the population1,2. In the majority of cases these are located at or near the splenic hilum. The pancreatic tail is also a common location for these lesions occurring in approximately 16% or 61 of 364 in a large autopsy series by Halpert and Gyorkey1 and 21.8% on large CT series3. Splenules may range in size from a few millimeters to several centimeters however they are most typically less than 2cm1,3. They are usually single but may be multiple. The majority are asymptomatic incidental findings usually on CT or ultrasound of the abdomen. Rarely, they may become symptomatic because of rupture, hemorrhage, torsion or cyst formation3. The primary clinical significance of these lesions resides in their mimicry of neoplasm.. Differentiation between splenule or splenic lobulation and neoplasm may be ...
Synonyms for ectopia testis in Free Thesaurus. Antonyms for ectopia testis. 3 words related to ectopia: posture, attitude, position. What are synonyms for ectopia testis?
Hi All, I need a second opinion on my 2 months old daughters MRI reports.As I failed to understand this report, I want to know answers for thousands of questions like if there is any diagonosis, surg...
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TY - JOUR. T1 - A tumor of the pancreatic tail requiring differential diagnosis. AU - Noguchi, Yubuko. AU - ono, takamasa. AU - Kaku, Toyoma. AU - Igarashi, Hisato. AU - Ito, Tetsuhide. PY - 2008/1/1. Y1 - 2008/1/1. UR - http://www.scopus.com/inward/record.url?scp=40349101997&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=40349101997&partnerID=8YFLogxK. M3 - Article. C2 - 18303600. AN - SCOPUS:40349101997. VL - 105. JO - Japanese Journal of Gastroenterology. JF - Japanese Journal of Gastroenterology. SN - 0446-6586. IS - 1. ER - ...
Another important feature to recognize in the pediatric chest is the normal thymic tissue in the anterior mediastinum. Normal thymic tissue, as demonstrated on this image, should not be confused with a mediastinal or pulmonary mass. ...
From our preliminary observation, it appears that GE cavitations are an aspect of more complex conditions associated with severe cerebral structural derangement. The awareness of this rare developmental abnormality involving the GE region may have implications in better understanding of the complex malformations caused by defective cellular proliferation and migration, such as lissencephalies. The fact that the lesions were bilateral and symmetric with an inverted "regular" open C shape, an epithelium-like lining, regular margins, and no apparent signs of hemorrhage (including the 2 cases with T1-weighted images) suggests a malformative rather than necrotic-clastic origin. Familial recurrence in 2 cases and the presence of frontal band heterotopias in 1 case further support such a hypothesis. Although the data are not extensive enough to conclude a statistical significance, the available ADC values (cases 1 and 4), albeit showing a slight trend toward mild reduction (0.85 SD, 0.09 m2/s), ...
Most common congenital abnormality of the small bowel. Majority of patients remain asymptomatic for their entire life. Majority of symptomatic patients present before the age of 2 years. GI bleeding is a common presenting symptom in children and adults. The most useful diagnostic tool in cases wi...
Bleeding: Some MD possess stomach tissue within it. Stomach tissue makes acid causing an ulcer which can bleed or result in a hole (perforation). The amount of bleeding from MD can be pretty massive. There is frankly bloody stools without associated abdominal pain. If the blood loss is severe, there may be sleepiness or shock ...
Neuroglial cells constitute a separate class of cells in the nervous system; they have been studied intensively since their original description by Virchow in 1846. As a rule anatomists find no difficulty in recognizing them by their staining properties, their shape and configuration as well as by their characteristic location between and around neurons. Electron microscopy has in recent years added much important subcellular detail and has shown how intermingled neurons and glial cells are, being separated from each other by narrow clefts 100 to 200 Å wide (figures 1 A, B and 5, plates 1, 2 and 4). These studies have not changed the well-established grouping of mammalian glial cells into two main classes, the oligodendrocytes and the astrocytes. It is customary to state that glial cells outnumber neurons by 10 to 1 in the vertebrate nervous sytem. They are, however, smaller and according to some rough estimates they make up as much as 50% of the volume of mammalian brains. That glial cells ...
The Juan Rosai Collection of Pathology Slides, a comprehensive collection of slide seminars including histopathology slides of rare and educational pathological cases
Background: Ectopic ureter with ipsilateral renal agenesis is a rare congenital urinary tract abnormality and presenting with recurrent epididymo-orchitis is still more rare. Patient management can be challenging in such a case. The diagnosis can generally be made with computed tomography imaging and retrograde pyelogram can also be useful in indeterminate cases. We report our experience of seven cases of ectopic ureter with renal agenesis and its management. Material and Methods: In between January 2013 and April 2017, seven patients were identified with ectopic ureter with renal agenesis. All presented with recurrent epididymo-orchitis. There demographic, diagnostic, and procedural data were recorded. Investigations included renal ultrasonography (USG), micturating cystography (MCU), cystoscopy, computed tomography (CT) and retrograde uretero-pyelography (RGP). All patients underwent ectopic ureter excision. Treatment outcome was assessed in terms of quality of life, recurrence and ...
In the present paper we report the case of a patient with papillary carcinoma of the thyroid with a coexistent intrathyroidal parathyroid gland and thymic tissue. All lesions were located in the right lobe of the thyroid, with imaging examinations not being able to differentiate between them, as findings consistent with either possible diagnosis were present (6). Eventually, diagnosis was established through histologic examination of the surgically excised tissue.. To the best of our knowledge, such a case with a combination of intrathyroidal parathyroid gland and thymic tissue with coexisting papillary carcinoma of the thyroid has been reported only once before by Kim et al. (7). In their work the authors report the case of a 29-year-old female patient with a history of right lobectomy due to papillary carcinoma of the thyroid. Her follow-up ultrasonography revealed a hyperechoic nodule, which was later identified by microscopy as ectopic thymic tissue containing a parathyroid gland.. Wu et al. ...
On abdominal ultrasonography (US), an intussuscepted inner segment was detected on the edematous outer bowel, at the left upper quadrant of the abdomen (Fig. 1). Abdominal computed tomography (CT) revealed an intussusception at the proximal jejunal loops without a lead point (Fig. 2). Three air reductions and one saline reduction were attempted. However, her symptoms recurred, and repeated US still detected jejunal intussusception. On laparoscopic examination for jejunal reduction and investigation of a lead point of intussusception, no lead point was detected. She still complained of intermittent abdominal pain 1 month after the laparoscopic examination. Capsule endoscopy was not performed owing to the risk of retention. Therefore, enteroscopy using a gastroscope (GIF-Q260; Olympus, Tokyo, Japan) was performed under fluoroscopic guidance and sedation. Enteroscopy revealed a few variable-sized polypoid lesions with erosions on the proximal jejunum. The largest lesion nearly obstructed the ...
Klippel-Feil syndrome (KFS) is a genetically heterogeneous disorder characterized by variable degrees of bony fusion in the cervical vertebra. KFS patients may have spinal instability, disc degeneration, scoliosis, malformation of laryngeal cartilage with vocal impairment, cleft palate, facial dysmorphism, and limb and hand abnormalities. Sprengel anomaly and sensorineural, conductive or mixed hearing impairment are common. The clinical triad of short neck, low posterior hairline and limited neck movement is observed in less than 50% of KFS patients.. The Klippel-Feil syndrome NGS panel consists of five genes: GDF3, GDF6, MEOX1, MYO18B and RIPPLY2.. Copy number variation (CNV) analysis of the Klippel-Feil syndrome genes is also offered as a panel. Additionally, CTGT offers a comprehensive test (both NGS and CNV panels) for these genes. Panel genes are also offered as individual sequencing and deletion/duplication tests unless otherwise indicated.. ...
MalaCards based summary : Meckels Diverticulum, also known as meckel diverticulum, is related to meckels diverticulum cancer and small intestine leiomyosarcoma, and has symptoms including meckel diverticulum An important gene associated with Meckels Diverticulum is FOXA2 (Forkhead Box A2), and among its related pathways/superpathways is Cardiac Progenitor Differentiation. Affiliated tissues include small intestine, bone and colon, and related phenotypes are homeostasis/metabolism and liver/biliary system ...
... refers to a group of disorders that arise from the abnormal migration of nerve cells during embryonic development. If the migration of neuroblasts is disturbed during neurogenesis, neural circuits do not form properly in the correct parts of the brain. This is referred to as cerebral dysgenesis.
QUESTION: Meckels diverticulum is the most common form of persistent __________ duct remnant. . . . . . ANSWER: The answer is vitelline duct
Ectopic ureter (or ureteral ectopia) is a medical condition where the ureter, rather than terminating at the urinary bladder, terminates at a different site. In males this site is usually the urethra, in females this is usually the urethra or vagina. It can be associated with renal dysplasia, frequent urinary tract infections, and urinary incontinence (usually continuous drip incontinence). Ectopic ureters are found in 1 of every 2000-4000 patients, and can be difficult to diagnose, but are most often seen on CT scans. ...
The physicians of the Wichita Urology Group are members of the American Urological Association and understand the importance of providing the most accurate
Splenosis is defined as an autotransplantation of the splenic tissue after splenic rupture or splenectomy, and occurs most frequently in the peritoneal cavity. Splenosis is usually asymptomatic and is found incidentally. We report a case of combined
To the Editor.-A recent article1 on the incidence of residual splenic tissue following splenectomy for trauma described a 26% occurrence of splenosis. This is a
As we all know, for malignant tumors, contrast CT imaging often shows quick-in and quick-out property. The abdominal masses of this patient were diagnosed as malignant tumors by contrast CT imaging because at artery phase the density of mass margin increased quickly while at venous phase the density decreased quickly, which shows the characteristic of malignant tumors. Therefore, we performed the operation. Unfortunately, finally we recognized that we misdiagnosed the disease which was actually ectopic spleen tissues.. As a matter of fact, we did not realize this disease prior to operation because we never heard of it. As a result, we performed the operation, and we figured out actually the tumors of liver and colon were spleen tissues. Then we reviewed some literatures, and acquired that this condition is splenosis, which often occurs in patients who ever underwent splenectomy7,8.. Intraabdominal splenosis is a generally asymptomatic entity incidentally diagnosed after the completion of CT scan ...
Artificial NeuroGlial Networks: 10.4018/978-1-59904-849-9.ch026: More than 50 years ago connectionist systems (CSs) were created with the purpose to process information in the computers like the human brain (McCulloch &
Choose and determine which version of Ocular Mutation chords and tabs by Parasitic Extirpation you can play. Last updated on 02.03.2014
What Is Your Diagnosis?. Diagnosis. Umbilical polyp (persistence of the omphalomesenteric duct [OMD]).. Clinical Course and Treatment. Surgical removal and intraoperative examination of the base of the polyp were performed. No other abnormalities were observed. The patient was examined by the pediatric gastrointestinal unit. Soft-tissue ultrasound detected no involvement of deeper tissue layers and scintigraphy using 99mTc-pertechnetate was negative for ectopic gastric mucosa.. Comment. The OMD is the structure that connects the embryonic midgut to the yolk sac to provide nourishment for the embryo while the placenta develops during the first weeks of intrauterine life. Under normal conditions, the OMD should obliterate between the fifth and ninth week of development and should have disappeared completely by the time of birth. In 2% of the population, involution is incomplete,1 resulting in various remnants, such as Meckels diverticulum (the most common form), fistula between the ileum and the ...
OBJECTIVES: To elaborate the imaging phenotype associated with a homozygous c.743C , del frameshift mutation in DAG1 leading to complete absence of both α- and β-dystroglycan previously reported in a consanguineous Israeli-Arab family. METHODS: We analyzed prenatal and postnatal imaging data of patients from a consanguineous Israeli-Arab kindred harboring the DAG1 mutation. RESULTS: The imaging studies (fetal ultrasound, CT scan and postnatal MRI) demonstrated: flat cortex (abnormally thick with irregular pebbled cortical-white matter border on MRI), hydrocephalus, scattered small periventricular heterotopia and subependymal hemorrhages and calcifications, z-shaped brainstem, and in addition an occipital encephalocele, vermian agenesis, and an elongated and thick tectum (tectocerebellar dysraphia ...
The progression of pre-malignant developmental lesions to tumours has been proved for several tissues such as colon (Macrae et al., 2009) and pancreas (Aguirre et al., 2003). In the brain, the relation between focal brain developmental disorders and brain cancer has been the subject of several studies aiming at establishing whether a common genetic and developmental origin for these disorders exists in cases with clear evidence of progression (Aronica and Crino, 2014; Guerrini and Dobyns, 2014; Hevner, 2015). However, for the majority of brain tumours, evidence of a developmental origin of the somatic mutations driving cancer is difficult to obtain. In this study, we generated a model of progressive brain tumour development where the same genetic drivers can give rise to cancer and heterotopia, and identified the signalling pathway that, once activated, promotes tumour development at the expense of heterotopia. Our model suggests that somatic embryonic mutations activating MAPK/ERK signalling ...
Parathyroid cysts are rare (0.8-3.41% of all parathyroid lesions) and usually arise secondary to cystic degeneration of parathyroid adenomas. Intrathyroidal parathyroid cysts are extremely rare with only three cases reported till date. We present a 24-year-old female with clinical and biochemical features of primary hyperparathyroidism (PHPT; Ca2 +: 12.1 mg/dl; intact parathyroid hormone (iPTH): 1283 pg/ml) and poor radiotracer uptake with minimal residual uptake in the left thyroid lobe at 2 and 4 h on Tc99m sestamibi imaging. Neck ultrasonography (USG) revealed 0.6×1 cm parathyroid posterior left lobe of thyroid along with 22×18 mm simple thyroid cyst. USG-guided fine-needle aspiration (FNA) and needle tip iPTH estimation (FNA-iPTH) from parathyroid lesion was inconclusive (114 pg/ml), necessitating FNA of thyroid cyst, which revealed high iPTH (3480 pg/ml) from the aspirate. The patient underwent a left hemithyroidectomy. A ,50% drop in serum iPTH 20 min after left hemithyroidectomy (29.4 ...
A fatal case of Lyme carditis occurring in a Suffolk farmworker is reported. Post-mortem examination of the heart showed pericarditis, focal myocarditis and prominent endocardial and interstitial fibrosis. The additional finding of endodermal heterotopia (mesothelioma) of the atrioventricular node raises the possibility that this could also be related to Lyme infection and account for the relatively frequent occurrence of atrioventricular block in this condition. Lyme disease should always be considered in a case of atrioventricular block, particularly in a young patient from a rural area. The heart block tends to improve and therefore only temporary pacing may be required.
Acromelic frontonasal dysostosis (AFND; MIM 603671) is a rare autosomal dominant disorder with distinct craniofacial, central nervous system and limb malformations. Typical craniofacial findings include severe frontonasal malformation with median facial cleft, marked separation of the nares, significant hypertelorism, and a carp shaped mouth. Central nervous system findings include severe intellectual disability, interhemispheric lipoma, agenesis of the corpus callosum, absent olfactory bulbs, pituitary abnormalities, and periventricular nodular heterotopia. Limb malformations include tibial hypoplasia, patellar hypoplasia, and preaxial polydactyly of the feet. AFND is caused by mutations in the ZSWIM6 gene, which encodes zinc finger SWIM domain-containing protein 6. Certain ZSWIM6 mutations can cause a phenotype consisting mainly of profound intellectual disability without craniofacial and limb malformations.. Read less ...
DIAGNOSIS Multiple intracranial meningeal extramedullary hematopoiesis DISCUSSION EMH occurs as a compensatory mechanism in a variety of disorders characterized by a chronic hematopoietic deficit such as thalassemia major and intermedia, congenital spherocytosis and sickle cell anemia, and bone marrow dysfunction seen in myelofibrosis and carcinomatosis. Lymphoma and leukemia can also result in EMH. Intracranial EMH is rare. The pathway of EMH involvement of the dura is unknown, but it is postulated that the dura has hematopoietic capacity in the fetus and EMH may originate from primitive rests. In addition, the epidural space is a potential space that can harbor metastatic or heterotopic tissue deposits. Various hypotheses exist to explain the development of hemopoietic tissue to supplement marrow production. Lyall [8] proposed the possibility of direct extension from marrow into epidural space. Knoblich [4] proposed that multipotential cells in the epidural space can be transformed into marrow ...

Choristoma - WikipediaChoristoma - Wikipedia

Choristoma "Choristoma" at Dorlands Medical Dictionary Lee, Kenneth H.; Roland, Peter S. (2013). "Heterotopias, Teratoma, and ... Choristomas, forms of heterotopia, are closely related benign tumors, found in abnormal locations. It is different from ... PMC 5343649 . Goswamy, Monika; Tabasum, Syeda; Kudva, Praveen; Gupta, Shikha (2012). "Osseous choristoma of the periodontium". ... while a choristoma is normal tissue growth in an abnormal location (e.g., gastric tissue located in distal ileum in Meckel ...
more infohttps://en.wikipedia.org/wiki/Choristoma

Cartilaginous Choristoma of the Gingiva: A Rare Clinical EntityCartilaginous Choristoma of the Gingiva: A Rare Clinical Entity

The term choristoma was first introduced by Krolls et al. [2]. Some researchers refer to choristoma as a tumor-like growth ... Choristoma, a congenital anomaly, is better described as a "heterotopic" rest of cells [1]. Choristoma is a more acknowledged ... L. Chou, L. S. Hansen, and T. E. Daniels, "Choristomas of the oral cavity: a review," Oral Surgery Oral Medicine and Oral ... Cartilaginous choristoma is apparently seen as a trouble-free, firm swelling [8]. This was seen in our case also where the ...
more infohttps://www.hindawi.com/journals/crid/2014/246965/

Naso-Oropharyngeal Choristoma (Hairy Polyps) in Adults: A New Case, and Review of the Literature | Acta Otorrinolaringológica...Naso-Oropharyngeal Choristoma (Hairy Polyps) in Adults: A New Case, and Review of the Literature | Acta Otorrinolaringológica...

Inicio Acta Otorrinolaringológica Española Naso-Oropharyngeal Choristoma (Hairy Polyps) in Adults: A New Case, and Review o... ... Naso-Oropharyngeal Choristoma (Hairy Polyps) in Adults: A New Case, and Review of the Literature ...
more infohttps://www.elsevier.es/en-revista-acta-otorrinolaringologica-espanola-402-estadisticas-S2173573514001173

Neuromuscular choristoma presenting with unilateral limb hypoplasia in a 3-year-old boy<...Neuromuscular choristoma presenting with unilateral limb hypoplasia in a 3-year-old boy<...

Neuromuscular choristoma presenting with unilateral limb hypoplasia in a 3-year-old boy. Muscle and Nerve. 2016 Oct 1;54(4):797 ... Neuromuscular choristoma presenting with unilateral limb hypoplasia in a 3-year-old boy. In: Muscle and Nerve. 2016 ; Vol. 54, ... Neuromuscular choristoma presenting with unilateral limb hypoplasia in a 3-year-old boy. / OBrien, Travis G.; Spinner, Robert ... OBrien, T. G., Spinner, R. J., & Boon, A. (2016). Neuromuscular choristoma presenting with unilateral limb hypoplasia in a 3- ...
more infohttps://mayoclinic.pure.elsevier.com/en/publications/neuromuscular-choristoma-presenting-with-unilateral-limb-hypoplas

Choristoma | Radiology Reference Article | Radiopaedia.orgChoristoma | Radiology Reference Article | Radiopaedia.org

A choristoma is simply a collection of microscopically normal cells or tissues in an abnormal location. This is different to a ... A choristoma is simply a collection of microscopically normal cells or tissues in an abnormal location. This is different to a ... Choristoma. Dr Maxime St-Amant ◉ and A.Prof Frank Gaillard ◉ ◈ et al. ... Choristomas of the seventh and eighth cranial nerves. AJNR Am J Neuroradiol. 1997;18 (2): 327-9. AJNR Am J Neuroradiol ( ...
more infohttps://images.radiopaedia.org/articles/choristoma?lang=us

Ocular Pathology: What is a phakomatous choristoma?Ocular Pathology: What is a phakomatous choristoma?

What is a phakomatous choristoma? Definition: Phakomatous choristoma is considered a lens anlage tumor described in 1971 by ... Included solar-lentigo, phakomatous choristoma (phacomatous-choristoma), congenital hereditary endothelial dystrophy, Fuchs ...
more infohttp://www.images.missionforvisionusa.org/anatomy/2006/03/what-is-phakomatous-choristoma.html

Lipomatous hamartomas and choristomas in inbred laboratory mice. by D L. Adkison and J P. Sundberg"Lipomatous" hamartomas and choristomas in inbred laboratory mice." by D L. Adkison and J P. Sundberg

... hamartomas or choristomas from nearly 10,000 mice examined at necropsy over a 24-month period. Hamartomas and choristomas were ... hamartomas or choristomas from nearly 10,000 mice examined at necropsy over a 24-month period. Hamartomas and choristomas were ... Animal, Animals-Laboratory, Brain-Neoplasms: ge, pa, ve, Breeding, Choristoma: ge, pa, ve, Female, Hamartoma: ge, pa, ve, Male ... Adkison, D L. and Sundberg, J P., " Lipomatous hamartomas and choristomas in inbred laboratory mice." (1991). Faculty ...
more infohttps://mouseion.jax.org/stfb1990_1999/212/

Vol. 13 Issue 5 | Jun 2003 | pp. 415 - 499 | EJOVol. 13 Issue 5 | Jun 2003 | pp. 415 - 499 | EJO

Eyelid phakomatous choristoma. E. Menca-Gutirrez, E. Gutierrez-Daz, J.R. Ricoy, B. Sarmiento-Torres ...
more infohttp://www.eur-j-ophthalmol.com/issue/ejo-vol-13-issue-5-june-2003

Articles by Frederick A. Jakobiec : CorneaArticles by Frederick A. Jakobiec : Cornea

Diffuse Epibulbar Complex Lacrimal-Cartilaginous Choristoma: Diagnostic Clues and Management. Grob, Seanna R.; Jakobiec, ...
more infohttp://journals.lww.com/corneajrnl/pages/author.aspx?firstName=Frederick&middleName=A.&lastName=Jakobiec

Middle Ear | Ear, Nose & Throat JournalMiddle Ear | Ear, Nose & Throat Journal

Glial choristoma of the middle ear December 20, 2013 , Karen A. Shemanski, DO; Spencer E. Voth, DO; Lana B. Patitucci, DO; ... Glial choristomas are isolated masses of mature brain tissue that are found outside the spinal cord or cranial cavity. These ...
more infohttps://www.entjournal.com/category/otology/middle-ear?page=2

Tongue disease - WikipediaTongue disease - Wikipedia

... for example Leiomyomatous hamartoma Glossoptosis Choristomata - For example, osseous choristoma of the tongue, a very rare ... Fan, SQ; Ou, YM; Liang, QC (Apr 2008). "Glial choristoma of the tongue: report of a case and review of the literature". ... ISBN 0-7216-2921-0. Yaqoob, N; Ahmed, Z; Muzaffar, S (Dec 2002). "Chondroid choristoma of tongue--a rare entity". JPMA. The ... Cartilagenous (chondroid), and glial choristomas may also very rarely occur on the tongue. Lingual thyroid Cleft tongue (bifid ...
more infohttps://en.wikipedia.org/wiki/Tongue_disease

Knigge K[au] - PubMed - NCBIKnigge K[au] - PubMed - NCBI

Intrasellar neural-adenohypophyseal choristoma. A morphological and immunocytochemical study.. Rhodes RH, Dusseau JJ, Boyd AS ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Knigge+K%5Bau%5D&dispmax=50

Oropharynx, Hypopharynx, and Parapharyngeal Space: Anatomy, Histology, Benign and Malignant Neoplasia | SpringerLinkOropharynx, Hypopharynx, and Parapharyngeal Space: Anatomy, Histology, Benign and Malignant Neoplasia | SpringerLink

Cartilaginous choristoma of the tongue. Gerodontology. 2009;26:78-80.PubMedCrossRefPubMedCentralGoogle Scholar ... Norris O, Mehra P. Chondroma (cartilaginous choristoma) of the tongue: report of a case. J Oral Maxillofac Surg. 2012;70:643-6. ... Kannar V, Prabhakar K, Shalini S. Cartilaginous choristoma of tonsil: a hidden clinical entity. J Oral Maxillofac Pathol. 2013; ... Cartilaginous choristoma of the tongue with an immunohistochemical study. BMJ Case Rep. 2012;2012. pii: bcr2012006752. https:// ...
more infohttps://link.springer.com/chapter/10.1007%2F978-3-319-76106-0_4

Eighth free download, or read Eighth onlineEighth free download, or read Eighth online

Choristomas of the Seventh and Eighth Cranial Nerves. Choristomasofthe Seventh and Eighth Cranial Nerves MichelleM. Smith, Jill ... E. Thompson, David Thomas, Mauricio Castillo, David Carrier, Suresh K. Mukherji, and David Gilliam Summary: Choristomas, masses ...
more infohttp://www.sputtr.com/eighth

Detection of Ectopic Intestinal Epithelium in an Ileocaecal Lymph Node from an Adult Crossbred Aberdeen Angus Cow | OMICS...Detection of Ectopic Intestinal Epithelium in an Ileocaecal Lymph Node from an Adult Crossbred Aberdeen Angus Cow | OMICS...

Cattle; Choristoma; Intestine; Lymph node; Diagnosis. Introduction. The development of an ectopic-non neoplasic normal tissue ... Epithelial choristoma was previously diagnosed in a mesenteric LN from a goat, and in mediastinal LN from cattle [7,9]. In ... All choristomas detected in LN were diagnosed in animals, which were positive for TB [7,9]. However, there has not been ... Pathogenesis of choristomas is poorly understood. However, at least three theories have been proposed for explaining the ...
more infohttps://www.omicsonline.org/detection-of-ectopic-intestinal-epithelium-in-an-ileocaecal-lymph-node-from-an-adult-crossbred-aberdeen-angus-cow-2157-7579.1000125.php?aid=10334&view=mobile

Links - Eye Conditions - Guinea Lynx RecordsLinks - Eye Conditions - Guinea Lynx Records

Osseous Choristoma. Osseous Choristoma can appear as an unusual white spot in the eye. ... Description of Osseous Choristoma.. *Lipid Deposit? In the eye?. Stan, a male, developed a white spot in the upper part of his ... choristoma. n. A mass formed by the faulty development of tissue of a type not normally found at that site.. The American ... Osseous Choristoma *White spot in eye... calcium deposit?. Moe, a male, developed a "white fleck" in his eye. ...
more infohttp://guinealynx.info/records/viewtopic.php?t=77

Links - Eye Conditions - Guinea Lynx RecordsLinks - Eye Conditions - Guinea Lynx Records

Osseous Choristoma. Osseous Choristoma can appear as an unusual white spot in the eye. ... Description of Osseous Choristoma.. *Lipid Deposit? In the eye?. Stan, a male, developed a white spot in the upper part of his ... choristoma. n. A mass formed by the faulty development of tissue of a type not normally found at that site.. The American ... Osseous Choristoma *White spot in eye... calcium deposit?. Moe, a male, developed a "white fleck" in his eye. ...
more infohttp://www.guinealynx.info/records/viewtopic.php?t=77&p=163

Links - Eye Conditions - Guinea Lynx RecordsLinks - Eye Conditions - Guinea Lynx Records

Osseous Choristoma. Osseous Choristoma can appear as an unusual white spot in the eye. ... Description of Osseous Choristoma.. *Lipid Deposit? In the eye?. Stan, a male, developed a white spot in the upper part of his ... choristoma. n. A mass formed by the faulty development of tissue of a type not normally found at that site.. The American ... Osseous Choristoma *White spot in eye... calcium deposit?. Moe, a male, developed a "white fleck" in his eye. ...
more infohttp://guinealynx.info/records/viewtopic.php?f=22&t=77&p=373

Links - Eye Conditions - Guinea Lynx RecordsLinks - Eye Conditions - Guinea Lynx Records

Osseous Choristoma. Osseous Choristoma can appear as an unusual white spot in the eye. ... Description of Osseous Choristoma.. *Lipid Deposit? In the eye?. Stan, a male, developed a white spot in the upper part of his ... choristoma. n. A mass formed by the faulty development of tissue of a type not normally found at that site.. The American ... Osseous Choristoma *White spot in eye... calcium deposit?. Moe, a male, developed a "white fleck" in his eye. ...
more infohttp://www.guinealynx.info/records/viewtopic.php?t=77&p=160

Zhao H[au] - PubMed - NCBIZhao H[au] - PubMed - NCBI

Clinicopathological study on conjunctival osseous choristoma].. Zhao Y, Li HQ, Zhao H, Lin JY. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?access_num=Zhao+H&link_type=AUTHORSEARCH&cmd=search&term=Zhao+H%5Bau%5D&dispmax=50
  • Choristoma, a congenital anomaly, is better described as a "heterotopic" rest of cells [ 1 ]. (hindawi.com)
  • Herein we report a case of cartilaginous choristoma in a 54-year-old male who presented with a swelling on right lower gingiva. (hindawi.com)
  • In a retrospective study, 37 male and 19 female inbred laboratory mice, from 1 to 36 weeks of age, were diagnosed with "lipomatous" hamartomas or choristomas from nearly 10,000 mice examined at necropsy over a 24-month period. (jax.org)