Chorismic Acid
The aroC gene of Aspergillus nidulans codes for a monofunctional, allosterically regulated chorismate mutase. (1/70)
The cDNA and the chromosomal locus of the aroC gene of Aspergillus nidulans were cloned and is the first representative of a filamentous fungal gene encoding chorismate mutase (EC 5.4.99.5), the enzyme at the first branch point of aromatic amino acid biosynthesis. The aroC gene complements the Saccharomyces cerevisiae aro7Delta as well as the A. nidulans aroC mutation. The gene consists of three exons interrupted by two short intron sequences. The expressed mRNA is 0.96 kilobases in length and aroC expression is not regulated on the transcriptional level under amino acid starvation conditions. aroC encodes a monofunctional polypeptide of 268 amino acids. Purification of this 30-kDa enzyme allowed determination of its kinetic parameters (k(cat) = 82 s(-1), n(H) = 1. 56, [S](0.5) = 2.3 mM), varying pH dependence of catalytic activity in different regulatory states, and an acidic pI value of 4.7. Tryptophan acts as heterotropic activator and tyrosine as negative acting, heterotropic feedback-inhibitor with a K(i) of 2.8 microM. Immunological data, homology modeling, as well as electron microscopy studies, indicate that this chorismate mutase has a dimeric structure like the S. cerevisiae enzyme. Site-directed mutagenesis of a crucial residue in loop220s (Asp(233)) revealed differences concerning the intramolecular signal transduction for allosteric regulation of enzymatic activity. (+info)Characterization of hydroxylaminobenzene mutase from pNBZ139 cloned from Pseudomonas pseudoalcaligenes JS45. A highly associated SDS-stable enzyme catalyzing an intramolecular transfer of hydroxy groups. (2/70)
Hydroxylaminobenzene mutase is the enzyme that converts intermediates formed during initial steps in the degradation of nitrobenzene to a novel ring-fission lower pathway in Pseudomonas pseudoalcaligenes JS45. The mutase catalyzes a rearrangement of hydroxylaminobenzene to 2-aminophenol. The mechanism of the reactions and the properties of the enzymes are unknown. In crude extracts, the hydroxylaminobenzene mutase was stable at SDS concentrations as high as 2%. A procedure including Hitrap-SP, Hitrap-Q and Cu(II)-chelating chromatography was used to partially purify the enzyme from an Escherichia coli clone. The partially purified enzyme was eluted in the void volume of a Superose-12 gel-filtration column even in the presence of 0.05% SDS in 25 mM Tris/HCl buffer, which indicated that it was highly associated. When the enzymatic conversion of hydroxylaminobenzene to 2-aminophenol was carried out in 18O-labeled water, the product did not contain 18O, as determined by GC-MS. The results indicate that the reaction proceeded by intramolecular transfer of the hydroxy group from the nitrogen to the C-2 position of the ring. The mechanism is clearly different from the intermolecular transfer of the hydroxy group in the non-enzymatic Bamberger rearrangement of hydroxylaminobenzene to 4-aminophenol and in the enzymatic hydroxymutation of chorismate to isochorismate. (+info)Archaeal shikimate kinase, a new member of the GHMP-kinase family. (3/70)
Shikimate kinase (EC 2.7.1.71) is a committed enzyme in the seven-step biosynthesis of chorismate, a major precursor of aromatic amino acids and many other aromatic compounds. Genes for all enzymes of the chorismate pathway except shikimate kinase are found in archaeal genomes by sequence homology to their bacterial counterparts. In this study, a conserved archaeal gene (gi1500322 in Methanococcus jannaschii) was identified as the best candidate for the missing shikimate kinase gene by the analysis of chromosomal clustering of chorismate biosynthetic genes. The encoded hypothetical protein, with no sequence similarity to bacterial and eukaryotic shikimate kinases, is distantly related to homoserine kinases (EC 2.7.1.39) of the GHMP-kinase superfamily. The latter functionality in M. jannaschii is assigned to another gene (gi591748), in agreement with sequence similarity and chromosomal clustering analysis. Both archaeal proteins, overexpressed in Escherichia coli and purified to homogeneity, displayed activity of the predicted type, with steady-state kinetic parameters similar to those of the corresponding bacterial kinases: K(m,shikimate) = 414 +/- 33 microM, K(m,ATP) = 48 +/- 4 microM, and k(cat) = 57 +/- 2 s(-1) for the predicted shikimate kinase and K(m,homoserine) = 188 +/- 37 microM, K(m,ATP) = 101 +/- 7 microM, and k(cat) = 28 +/- 1 s(-1) for the homoserine kinase. No overlapping activity could be detected between shikimate kinase and homoserine kinase, both revealing a >1,000-fold preference for their own specific substrates. The case of archaeal shikimate kinase illustrates the efficacy of techniques based on reconstruction of metabolism from genomic data and analysis of gene clustering on chromosomes in finding missing genes. (+info)Essential PchG-dependent reduction in pyochelin biosynthesis of Pseudomonas aeruginosa. (4/70)
The biosynthetic genes pchDCBA and pchEF, which are known to be required for the formation of the siderophore pyochelin and its precursors salicylate and dihydroaeruginoate (Dha), are clustered with the pchR regulatory gene on the chromosome of Pseudomonas aeruginosa. The 4.6-kb region located downstream of the pchEF genes was found to contain three additional, contiguous genes, pchG, pchH, and pchI, probably forming a pchEFGHI operon. The deduced amino acid sequences of PchH and PchI are similar to those of ATP binding cassette transport proteins with an export function. PchG is a homolog of the Yersinia pestis and Y. enterocolitica proteins YbtU and Irp3, which are involved in the biosynthesis of yersiniabactin. A null mutation in pchG abolished pyochelin formation, whereas mutations in pchH and pchI did not affect the amounts of salicylate, Dha, and pyochelin produced. The pyochelin biosynthetic genes were expressed from a vector promoter, uncoupling them from Fur-mediated repression by iron and PchR-dependent induction by pyochelin. In a P. aeruginosa mutant lacking the entire pyochelin biosynthetic gene cluster, the expressed pchDCBA and pchEFG genes were sufficient for salicylate, Dha, and pyochelin production. Pyochelin formation was also obtained in the heterologous host Escherichia coli expressing pchDCBA and pchEFG together with the E. coli entD gene, which provides a phosphopantetheinyl transferase necessary for PchE and PchF activation. The PchG protein was purified and used in combination with PchD and phosphopantetheinylated PchE and PchF in vitro to produce pyochelin from salicylate, L-cysteine, ATP, NADPH, and S-adenosylmethionine. Based on this assay, a reductase function was attributed to PchG. In summary, this study completes the identification of the biosynthetic genes required for pyochelin formation from chorismate in P. aeruginosa. (+info)The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan. (5/70)
The crystal structure of anthranilate synthase (AS) from Serratia marcescens, a mesophilic bacterium, has been solved in the presence of its substrates, chorismate and glutamine, and one product, glutamate, at 1.95 A, and with its bound feedback inhibitor, tryptophan, at 2.4 A. In comparison with the AS structure from the hyperthermophile Sulfolobus solfataricus, the S. marcescens structure shows similar subunit structures but a markedly different oligomeric organization. One crystal form of the S. marcescens enzyme displays a bound pyruvate as well as a putative anthranilate (the nitrogen group is ambiguous) in the TrpE subunit. It also confirms the presence of a covalently bound glutamyl thioester intermediate in the TrpG subunit. The tryptophan-bound form reveals that the inhibitor binds at a site distinct from that of the substrate, chorismate. Bound tryptophan appears to prevent chorismate binding by a demonstrable conformational effect, and the structure reveals how occupancy of only one of the two feedback inhibition sites can immobilize the catalytic activity of both TrpE subunits. The presence of effectors in the structure provides a view of the locations of some of the amino acid residues in the active sites. Our findings are discussed in terms of the previously described AS structure of S. solfataricus, mutational data obtained from enteric bacteria, and the enzyme's mechanism of action. (+info)Microbial origin of plant-type 2-keto-3-deoxy-D-arabino-heptulosonate 7-phosphate synthases, exemplified by the chorismate- and tryptophan-regulated enzyme from Xanthomonas campestris. (6/70)
Enzymes performing the initial reaction of aromatic amino acid biosynthesis, 2-keto-3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthases, exist as two distinct homology classes. The three classic Escherichia coli paralogs are AroA(I) proteins, but many members of the Bacteria possess the AroA(II) class of enzyme, sometimes in combination with AroA(I) proteins. AroA(II) DAHP synthases until now have been shown to be specifically dedicated to secondary metabolism (e.g., formation of ansamycin antibiotics or phenazine pigment). In contrast, here we show that the Xanthomonas campestris AroA(II) protein functions as the sole DAHP synthase supporting aromatic amino acid biosynthesis. X. campestris AroA(II) was cloned in E. coli by functional complementation, and genes corresponding to two possible translation starts were expressed. We developed a 1-day partial purification method (>99%) for the unstable protein. The recombinant AroA(II) protein was found to be subject to an allosteric pattern of sequential feedback inhibition in which chorismate is the prime allosteric effector. L-Tryptophan was found to be a minor feedback inhibitor. An N-terminal region of 111 amino acids may be located in the periplasm since a probable inner membrane-spanning region is predicted. Unlike chloroplast-localized AroA(II) of higher plants, X. campestris AroA(II) was not hysteretically activated by dithiols. Compared to plant AroA(II) proteins, differences in divalent metal activation were also observed. Phylogenetic tree analysis shows that AroA(II) originated within the Bacteria domain, and it seems probable that higher-plant plastids acquired AroA(II) from a gram-negative bacterium via endosymbiosis. The X. campestris AroA(II) protein is suggested to exemplify a case of analog displacement whereby an ancestral aroA(I) species was discarded, with the aroA(II) replacement providing an alternative pattern of allosteric control. Three subgroups of AroA(II) proteins can be recognized: a large, central group containing the plant enzymes and that from X. campestris, one defined by a three-residue deletion near the conserved KPRS motif, and one possessing a larger deletion further downstream. (+info)The emerging periplasm-localized subclass of AroQ chorismate mutases, exemplified by those from Salmonella typhimurium and Pseudomonas aeruginosa. (7/70)
BACKGROUND: Chorismate mutases of the AroQ homology class are widespread in the Bacteria and the Archaea. Many of these exist as domains that are fused with other aromatic-pathway catalytic domains. Among the monofunctional AroQ proteins, that from Erwinia herbicola was previously shown to have a cleavable signal peptide and located in the periplasmic compartment. Whether or not this might be unique to E. herbicola was unknown. RESULTS: The gene coding for the AroQ protein was cloned from Salmonella typhimurium, and the AroQ protein purified from both S. typhimurium and Pseudomonas aeruginosa was shown to have a periplasmic location. The periplasmic chorismate mutases (denoted *AroQ) are shown to be a distinct subclass of AroQ, being about twice the size of cytoplasmic AroQ proteins. The increased size is due to a carboxy-terminal extension of unknown function. In addition, a so-far novel aromatic aminotransferase was shown to be present in the periplasm of P. aeruginosa. CONCLUSIONS: Our analysis has detected a number of additional *aroQ genes. The joint presence of *AroQ, cyclohexadienyl dehydratase and aromatic aminotransferase in the periplasmic compartment of P. aeruginosa comprises a complete chorismate-to-phenylalanine pathway and accounts for the "hidden overflow pathway" to phenylalanine described previously. (+info)Clustering of isochorismate synthase genes menF and entC and channeling of isochorismate in Escherichia coli. (8/70)
There are two isochorismate synthase genes entC and menF in Escherichia coli. They encode enzymes (isochorismate synthase, EC 5.4.99.6) which reversibly synthesize isochorismic acid from chorismic acid. The genes share a 24.2% identity but are differently regulated. Activity of the MenF isochorismate synthase is significantly increased under anaerobic conditions whereas the activity of the EntC isochorismate synthase is greatly stimulated during growth in an iron deficient medium. Isochorismic acid synthesized by EntC is mainly channeled into enterobactin synthesis whereas isochorismic acid synthesized by MenF is mainly channeled into menaquinone synthesis. When menF or entC were separately placed onto overexpression plasmids and the plasmids introduced into a menF(-)/entC(-) double mutant in two separate experiments, the isochorismate formed was fed into both, the menaquinone and the enterobactin pathway. Moreover, in spite of a high isochorismate synthase activity menaquinone and enterobactin formation were not fully restored, indicating that isochorismate was lost by diffusion. Thus, under these conditions channeling was not observed. We conclude that in E. coli the chromosomal position of both menF and entC in their respective clusters is a prerequisite for channeling of isochorismate in both pathways. (+info)
Chorismic acid
The name chorismic acid derives from a classical Greek word χωρίζω meaning "to separate", because the compound plays a role as ... Chorismic acid, more commonly known as its anionic form chorismate, is an important biochemical intermediate in plants and ... 3-Dihydroxybenzoic acid (DHB) used for enterobactin biosynthesis The plant hormone salicylic acid Many alkaloids and other ... ISBN 0-19-864226-1. Gibson, F. (1999). "The elusive branch-point compound of aromatic amino acid biosynthesis". Trends in ...
Vitamin K2
Many bacteria synthesize menaquinones from chorismic acid. They use it as a part of the electron transport chain, playing a ... in conversion of peptide-bound glutamic acid (Glu) to γ-carboxy glutamic acid (Gla) in these proteins). Carboxylation of these ... Oxygen, heme, and menaquinones are needed for many species of lactic acid bacteria to conduct respiration. Vitamin K Vitamin K1 ...
Pseudomonas aeruginosa
The enzymes encoded by these operons convert chorismic acid to PCA. The products of three key genes, phzH, phzM, and phzS then ... The biofilm matrix of P. aeruginosa is composed of nucleic acids, amino acids, carbohydrates, and various ions. It mechanically ... However, salicylic acid can inhibit pyocyanin production. One in ten hospital-acquired infections is from Pseudomonas. Cystic ... Usually a sterile gauze soaked with acetic acid is placed on the wound after irrigation with normal saline. Dressing would be ...
Frank William Ernest Gibson
Structure of chorismic acid, a new intermediate in aromatic biosynthesis. Nature 198, 388-389 Gibson, F. (1995) Chorismic Acid ... his wife Margaret and his research group discovered chorismic acid. Gibson described the naming of chorismic acid" 'My father- ... He and his research group were responsible for the discovery of chorismic acid. He later worked at The Australian National ... They continued to explore the biochemistry of chorismic acid and of its many metabolites including ubiquinone, central to the ...
Anthranilic acid
... was first obtained by base-induced degradation of indigo. Anthranilic acid is biosynthesized from chorismic ... tolfenamic acid, flufenamic acid, and meclofenamic acid are derived from fenamic acid or anthranilic acid and are called " ... Fenamic acid is a derivative of anthranilic acid,: 235 which in turn is a nitrogen isostere of salicylic acid, which is the ... Anthranilic acid is an aromatic acid with the formula C6H4(NH2)(CO2H) and has a sweetish taste. The molecule consists of a ...
Chorismate synthase
"The enzymic synthesis of chorismic and prephenic acids from 3-enolpyruvylshikimic acid 5-phosphate". J. Biol. Chem. 242 (1): 82 ... It is a protein of about 360 to 400 amino-acid residues. The shikimate pathway synthesises aromatic amino acids as well as ... fungi and plants for the biosynthesis of aromatic amino acids. It catalyzes the 1,4-trans elimination of the phosphate group ...
EPSP synthase
"The enzymic synthesis of chorismic and prephenic acids from 3-enolpyruvylshikimic acid 5-phosphate". The Journal of Biological ... Basic and amino acids in the active site are involved in deprotonation of the hydroxyl group of PEP and in the proton-exchange ... Eventually this results in organism death from lack of aromatic amino acids the organism requires to survive. A version of the ... Maeda H, Dudareva N (2012). "The shikimate pathway and aromatic amino Acid biosynthesis in plants". Annual Review of Plant ...
Aureothin
Regarding the biosynthesis of aureothin, the biosynthetic pathway would be begun with chorismic acid. P-nitrobenzoate is ...
Vibriobactin
DHB is synthesized from chorismic acid by a series of enzymes: VibA, VibB, and VibC. DHB is linked to NSPD by VibE, VibB and ... The components of vibriobactin are three 2,3-dihydroxybenzoic acid (DHB), two threonine (Thr), and one norspermidine (NSPD). ...
Phenazine
... biosynthesis branches off the shikimic acid pathway at a point subsequent to chorismic acid. Two molecules of this ... Sulfuric acid dissolves it, forming a deep-red solution. Classically phenazine are prepared by the reaction of nitrobenzene and ... When heated with concentrated hydrochloric acid the amino group is replaced by the hydroxyl group and the phenolic eurhodols ... It dissolves in concentrated sulfuric acid with a yellowish-green fluorescence. The rhodamines, which are closely related to ...
Prephenate dehydratase
... enzymes converting chorismic acid into prephenic acid and their relationships to prephenate dehydratase and prephenate ... CERUTTI P, GUROFF G (1965). "Enzymatic Formation of Phenylpyruvic Acid in Pseudomonas Sp. (Atcc 11299A) and ITS Regulation". J ...
Noscapine
Chorismic acid is a precursor to the amino acid tyrosine, the source of nitrogen in benzylisoquinoline alkaloids. Tyrosine can ... The biosynthesis of noscapine in P. somniferum begins with chorismic acid, which is synthesized via the shikimate pathway from ... and opic acid (6-formyl-2,3-dimethoxybenzoic acid). When noscapine is reduced with zinc/HCl, the bond C1−C3′ saturates and the ... In aqueous solution of sulfuric acid and heating it dissociates into cotarnine (4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3] ...
Rosavin
Shikimic acid is then converted to chorismic acid through various enzymes derived from the shikimic-chorismic acid pathway. ... which is produced from the shikimic-chorismic acid pathway. Shikimic acid is made from the precursor compounds erythrose-4- ... Chorismate mutase then converts chorismic acid to prephenate via a Claisen rearrangement (1,3-sigmatropic rearrangement). ... In the first step of rosavin synthesis, PAL converts phenylalanine to cinnamic acid. From cinnamic acid, cinnamyl-CoA ester is ...
Glucobrassicin
... chorismic acid. Tryptophan is converted to indole-3-acetaldoxime (IAOx) by cytochrome p450 enzymes (the redundant CYP92B3 and ... The biosynthesis of glucobrassicin begins with tryptophan produced through several steps from the shikimic acid pathway ...
Rubicordifolin
Shikimate is converted into chorismic acid, which is further converted into 2-succinylbenzoic acid through a TPP-dependent ... After 2-succinylbenzoic acid has been produced, a cyclization, a prenylation, a methylation, and an oxidation occur which ... Mechanistically, it is proposed that the phenylboronic acid promotes a cyclization that is followed by a Diels-Alder reaction ...
Pyocyanin
In this reaction the enzyme PhzE catalyzes the loss of the hydroxyl group from C4 of Chorismic Acid as well as the transfer of ... Biosynthesis can be impaired by disrupting the aro pathway which is needed for the synthesis of chorismic acid from shikimate. ... 6-carboxylic acid (THPCA). In the final step of phenazine-1-carboxylic acid synthesis the enzyme PhzG catalyzes the oxidation ... Mitochondrial electron carriers ubiquinone and nicotinic acid are also susceptible to pyocyanin. The cell cycle can be ...
Enterobactin
Chorismic acid, an aromatic amino acid precursor, is converted to 2,3-dihydroxybenzoic acid (DHB) by a series of enzymes, EntA ... These initial studies established the structure and its relationship to 2,3-dihydroxybenzoic acid. Dertz EA, Xu J, Stintzi A, ... O'Brien IG, Cox GB, Gibson F (March 1970). "Biologically active compounds containing 2,3-dihydroxybenzoic acid and serine ...
Tacrolimus
The starter unit, DHCHC from the chorismic acid is formed by fkbO enzyme and loaded onto CoA-ligase domain (CoL). Then, it ... After the last step (module 10) of PKS 1, one molecule of L-pipecolic acid formed from L-lysine and catalyzed through fkbL ... The process of L-pipecolic acid synthesis is NRPS enforced by fkbP enzyme. After synthesizing the entire subunits, the molecule ... The fundamental units for biosynthesis are following: one molecule of 4,5-dihydroxycyclohex-1-enecarboxylic acid (DHCHC) as a ...
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
From these six genes, EntA, EntB, and EntC are responsible for the synthesis of DHB from chorismic acid and the gene EntA ... Young IG, Gibson F (May 1969). "Regulation of the enzymes involved in the biosynthesis of 2,3-dihydroxybenzoic acid in ... 3-dihydroxybenzoic acid (2,3-DHB or simply DHB). In times of iron deficiency, iron uptake is controlled by three genes: ent, ... 3-dihydroxybenzoic acid dehydrogenase from Escherichia coli". Acta Crystallographica D. 62 (Pt 7): 734-40. doi:10.1107/ ...
C10H10O6
The molecular formula C10H10O6 (molar mass: 226.18 g/mol, exact mass: 226.0477 u) may refer to: Chorismic acid Prephenic acid ...
Cyclohexanecarboxylic acid
... acid chlorogenic acid chorismic acid dicyclomine quinic acid shikimic acid tranexamic acid Quinic acid Shikimic acid Chorismic ... Cyclohexanecarboxylic acid exhibits the reactions typical of carboxylic acids, including its conversion to the acid chloride ... Cyclohexanecarboxylic acid is the organic compound with the formula C6H11CO2H. It is the carboxylic acid of cyclohexane. It is ... Cyclohexanecarboxylic acid is a precursor to the nylon-6 precursor caprolactam via its reaction with nitrosylsulfuric acid. It ...
3-Dehydroquinic acid
... undergoes five further enzymatic steps in the remainder of the shikimate pathway to chorismic acid, a ... 3-Dehydroquinic acid (DHQ) is the first carbocyclic intermediate of the shikimate pathway. It is created from 3- ... 3-Dehydroquinate goes through beta oxidation, similar to fatty acids. Then, this compound (6-oxo-3-dehydro-quinate) is ... Morrow, Gary W. (2016). "The Shikimate Pathway: Biosynthesis of Phenolic Products from Shikimic Acid". Oxford University Press ...
List of MeSH codes (D02)
... aurintricarboxylic acid MeSH D02.241.223.268.220 - chlorogenic acid MeSH D02.241.223.268.250 - chorismic acid MeSH D02.241. ... quinic acid MeSH D02.241.511.852 - shikimic acid MeSH D02.241.511.902 - sugar acids MeSH D02.241.511.902.107 - ascorbic acid ... edetic acid MeSH D02.241.081.038.455 - egtazic acid MeSH D02.241.081.038.581 - iodoacetic acid MeSH D02.241.081.038.581.400 - ... hexuronic acids MeSH D02.241.081.844.915.400.500 - iduronic acid MeSH D02.241.081.901.177 - aconitic acid MeSH D02.241.081.901. ...
DeCS
Chorismic Acid - Preferred Concept UI. M0004344. Scope note. A cyclohexadiene carboxylic acid derived from SHIKIMIC ACID and a ... A cyclohexadiene carboxylic acid derived from SHIKIMIC ACID and a precursor for the biosynthesis of UBIQUINONE and the AROMATIC ... 91; was see under CYCLOHEXANECARBOXYLIC ACIDS 1975-90. History Note:. 91(75); was see under CYCLOHEXANECARBOXYLIC ACIDS 1975-90 ... 1,5-Cyclohexadiene-1-carboxylic acid, 3-((1-carboxyethenyl)oxy)-4-hydroxy-, (3R-trans)- ...
Novel enzymology in futalosine-dependent menaquinone biosynthesis - PubMed
MeSH Browser
Chorismic Acid Preferred Term Term UI T008229. Date01/01/1999. LexicalTag NON. ThesaurusID ... Carboxylic Acids [D02.241] * Acids, Carbocyclic [D02.241.223] * Cyclohexanecarboxylic Acids [D02.241.223.268] * Abscisic Acid [ ... Chorismic Acid Preferred Concept UI. M0004344. Registry Number. GI1BLY82Y1. Related Numbers. 617-12-9. Scope Note. A ... Chorismic Acid. Tree Number(s). D02.241.223.268.250. D02.455.426.392.368.367.379.374. Unique ID. D002827. RDF Unique Identifier ...
MeSH Browser
Chorismic Acid Preferred Term Term UI T008229. Date01/01/1999. LexicalTag NON. ThesaurusID ... Carboxylic Acids [D02.241] * Acids, Carbocyclic [D02.241.223] * Cyclohexanecarboxylic Acids [D02.241.223.268] * Abscisic Acid [ ... Chorismic Acid Preferred Concept UI. M0004344. Registry Number. GI1BLY82Y1. Related Numbers. 617-12-9. Scope Note. A ... Chorismic Acid. Tree Number(s). D02.241.223.268.250. D02.455.426.392.368.367.379.374. Unique ID. D002827. RDF Unique Identifier ...
Prefix: iso
... iso-chorismic acid,noun,E0217967,chorismic acid,noun,E0557106,yes iso-,iso-chorismic,adj,E0451400,chorismic,adj,E0566715,yes ... isochorismic acid,noun,E0217967,chorismic acid,noun,E0557106,yes iso,isochorismic,adj,E0451400,chorismic,adj,E0566715,yes iso, ... isouric acid,noun,E0596373,uric acid,noun,E0063625,yes iso,isoursodeoxycholic acid,noun,E0503400,ursodeoxycholic acid,noun, ... iso-caproic acid,noun,E0566377,caproic acid,noun,E0205927,yes iso-,iso-center,noun,E0335293,center,noun,E0015833,yes iso-,iso- ...
Structure of the D-alanylgriseoluteic acid biosynthetic protein EhpF, an atypical member of the ANL superfamily of adenylating...
... that functions in the biosynthetic pathway leading to the broad-spectrum antimicrobial compound D-alanylgriseoluteic acid (AGA ... native to certain strains of Pantoea agglomerans encodes the proteins that are required for the conversion of chorismic acid to ... Structure of the D-alanylgriseoluteic acid biosynthetic protein EhpF, an atypical member of the ANL superfamily of adenylating ... Structure of the D-alanylgriseoluteic acid biosynthetic protein EhpF, an atypical member of the ANL superfamily of adenylating ...
DeCS
An isomerase that catalyzes the conversion of chorismic acid to prephenic acid. EC 5.4.99.5. ... An isomerase that catalyzes the conversion of chorismic acid to prephenic acid. EC 5.4.99.5.. ... Cyclohexanecarboxylic Acids (1969-1974). Isomerases (1969-1974). Vinyl Compounds (1972-1974). Public MeSH Note:. 91; was see ...
MESH TREE NUMBER CHANGES - 2007 MeSH. September 14, 2006
D6.472.759.367.125 Chorismic Acid D2.455.426.392.368.367.379.374 Chromaffin Granules A6.224.207 A6.224.161.500 Chromium Alloys ... Guanylic Acid D3.438.759.646.454.525 5,8,11,14-Eicosatetraynoic Acid D10.251.355.255.49 D10.251.355.255.205 5-alpha- ... D2.455.426.559.847.638.555.220 Amino Acid Metabolism, Inborn Errors C16.320.565.66 C18.452.648.66 Amino Acid Transport ... D3.132.577.500 Nucleic Acid Denaturation E5.393.640 G5.720 Nucleoside Q D3.438.759.590.454.500 Nutrition G2.513 (Replaced for ...
Prefix: iso
... iso-chorismic acid,noun,E0217967,chorismic acid,noun,E0557106,yes iso-,iso-chorismic,adj,E0451400,chorismic,adj,E0566715,yes ... isochorismic acid,noun,E0217967,chorismic acid,noun,E0557106,yes iso,isochorismic,adj,E0451400,chorismic,adj,E0566715,yes iso, ... isouric acid,noun,E0596373,uric acid,noun,E0063625,yes iso,isoursodeoxycholic acid,noun,E0503400,ursodeoxycholic acid,noun, ... iso-caproic acid,noun,E0566377,caproic acid,noun,E0205927,yes iso-,iso-center,noun,E0335293,center,noun,E0015833,yes iso-,iso- ...
NDF-RT Code NDF-RT Name
Human N0000168121 Chorismate Mutase N0000166668 Chorismic Acid N0000007918 Chromans N0000007919 Chromates N0000169072 Chromatin ... Neutral N0000006806 Amino Acids N0000011372 Amino Acids, Acidic N0000011248 Amino Acids, Aromatic N0000011332 Amino Acids, ... Acyclic N0000008269 Acids, Aldehydic N0000007628 Acids, Carbocyclic N0000007629 Acids, Heterocyclic N0000007630 Acids, ... Amino Acid Isomerases N0000167825 Amino Acid Oxidoreductases N0000169801 Amino Acid Transport System A N0000169803 Amino Acid ...
TERM
Chorismic Acid Choristoma Choroid Choroid Diseases Choroid Hemorrhage Choroid Neoplasms Choroid Plexus Choroid Plexus Neoplasms ... Amino Acids Amino Acids, Acidic Amino Acids, Aromatic Amino Acids, Basic Amino Acids, Branched-Chain Amino Acids, Cyclic Amino ... Acid Ceramidase Acid Etching, Dental Acid Phosphatase Acid Rain Acid Sensing Ion Channel Blockers Acid Sensing Ion Channels ... Acids Acids, Acyclic Acids, Aldehydic Acids, Carbocyclic Acids, Heterocyclic Acids, Noncarboxylic Acidulated Phosphate Fluoride ...
c33c
... underestimates chernobyl hidrotic lipoatrophy acis margaritifer maturating ack2 ack1 acin acii orbiniidae nivaquine acid acic ... dimethylnona hypacusia palmoxirate greatly mss11 simkaniaceae brent brenn frontal interest pichia antimutagenic chorismic ... methylbenzylamine hymenolepis countries mauritian sherpa trout bicarbonate grimes toadfish melanoplinae prolymphocyte acids ...
Conversion of chorismic acid2
- A cluster of approximately 16 genes, including ehpF, located on a 200 kbp plasmid native to certain strains of Pantoea agglomerans encodes the proteins that are required for the conversion of chorismic acid to AGA. (nih.gov)
- An isomerase that catalyzes the conversion of chorismic acid to prephenic acid. (bvsalud.org)