Chorionic Gonadotropin, beta Subunit, Human
Chorionic Gonadotropin
Choriocarcinoma
Disulfides
Glycoprotein Hormones, alpha Subunit
Peptide Fragments
Gonadotropins
Luteinizing Hormone
Receptors, LH
Gonadotropins, Equine
Receptors, Gonadotropin
Follicle Stimulating Hormone
Gonadotropins, Pituitary
The effectiveness of non-surgical management of early interstitial pregnancy: a report of ten cases and review of the literature. (1/497)
OBJECTIVE: To assess the effectiveness of non-surgical management of interstitial pregnancy. DESIGN: A prospective interventional study. SUBJECTS: Eleven women with the ultrasound diagnosis of interstitial ectopic pregnancy. METHODS: Women with suspected early pregnancy complications were examined by transvaginal ultrasound. Those with the diagnosis of interstitial pregnancy were offered non-surgical treatment with methotrexate, which was administered systemically or by local injection. Follow-up with regular measurements of beta-human chorionic gonadotropin and ultrasound scans continued until the pregnancy had resolved completely. RESULTS: Ten women were managed non-surgically, and one woman opted for surgery. Five women received systemic and five local methotrexate. Local therapy was successful in all five cases (100%), whereas four out of five (80%) women receiving systemic methotrexate were cured. Significant side-effects were noted in two women following systemic therapy. In comparison, there were no side-effects in the group of women who received local therapy. There were no significant differences between the two treatment groups in the length of time taken for the pregnancy to resolve. CONCLUSIONS: Non-surgical treatment of interstitial pregnancy with methotrexate appears to be safe and effective. Local administration appears to be more successful and better tolerated by patients and may be used as the first-line therapy. (+info)Combined treatment modality for intracranial germinomas: results of a multicentre SFOP experience. Societe Francaise d'Oncologie Pediatrique. (2/497)
Conventional therapy for intracranial germinomas is craniospinal irradiation. In 1990, the Societe Francaise d'Oncologie Pediatrique initiated a study combining chemotherapy (alternating courses of etoposide-carboplatin and etoposide-ifosfamide for a recommended total of four courses) with 40 Gy local irradiation for patients with localized germinomas. Metastatic patients were allocated to receive low-dose craniospinal radiotherapy. Fifty-seven patients were enrolled between 1990 and 1996. Forty-seven had biopsy-proven germinoma. Biopsy was not performed in ten patients (four had diagnostic tumour markers and in six the neurosurgeon felt biopsy was contraindicated). Fifty-one patients had localized disease, and six leptomeningeal dissemination. Seven patients had bifocal tumour. All but one patient received at least four courses of chemotherapy. Toxicity was mainly haematological. Patients with diabetus insipidus (n = 25) commonly developed electrolyte disturbances during chemotherapy. No patient developed tumour progression during chemotherapy. Fifty patients received local radiotherapy with a median dose of 40 Gy to the initial tumour volume. Six metastatic patients, and one patient with localized disease who stopped chemotherapy due to severe toxicity, received craniospinal radiotherapy. The median follow-up for the group was 42 months. Four patients relapsed 9, 10, 38 and 57 months after diagnosis. Three achieved second complete remission following salvage treatment with chemotherapy alone or chemo-radiotherapy. The estimated 3-year survival probability is 98% (CI: 86.6-99.7%) and the estimated 3-year event-free survival is 96.4% (CI: 86.2-99.1%). This study shows that excellent survival rates can be achieved by combining chemotherapy and local radiotherapy in patients with non-metastatic intracranial germinomas. (+info)Hyperreactio luteinalis associated with chronic renal failure. (3/497)
Hyperreactio luteinalis is a rare benign condition characterized by bilateral ovarian enlargement associated with pregnancies where high concentrations of maternal serum human chorionic gonadotrophins are present. This condition may mimic the ovarian hyperstimulation syndrome. We report a case of a 34 year old woman with a history of chronic renal failure on haemodialysis who presented at 10 weeks' gestational age with hyperreactio luteinalis which was treated conservatively. Because of chronic renal failure, the presentation and course of the disease was different from that which has been previously reported. (+info)Characterization of human placental explants: morphological, biochemical and physiological studies using first and third trimester placenta. (4/497)
The primary objective of this study was to characterize an in-vitro model of the human placenta using morphological, biochemical and physiological parameters. Placental villi were obtained from normal first trimester and term pregnancies. The villi were incubated with Dulbecco's modified Eagle's medium: Ham's F12 nutrient mixture in a shaking water bath at 37 degrees C for up to 310 min. The viability was determined by the production of beta human chorionic gonadotrophin (HCG) and lactic dehydrogenase (LDH) and the incorporation of [3H]thymidine, [3H]L-leucine and L-[U14C]arginine, while ultrastructure was assessed by transmission electron microscopy. In the first and third trimester group, the release into the medium of the intracellular enzyme LDH remained unaltered throughout the experiment. By contrast, beta-HCG concentrations increased linearly and concentrations were higher in the first trimester than term villi (354.5 +/- 37.8 versus 107 +/- 8.1 IU/g villi protein; P < 0.001). Electron microscopy confirmed preservation of tissue viability for up to 4 h of incubation. The incorporation of thymidine (12.2 +/- 2.9 versus 5.2 +/- 0.5 nmol/g villi protein; P < 0.05), leucine (9.4 +/- 2.1 versus 1.9 +/- 0.4 nmol/g villi protein; P < 0.02) and arginine (17 +/- 4.4 versus 4.2 +/- 0.5 nmol/g villi protein; P < 0.05) were markedly higher in early than in term placenta. Furthermore, placental uptake of L-leucine by the first (9.4 +/- 2.1 versus 17 + 4.4 mol/g villi protein; P < 0.001) and third trimester placental villi (1.9 +/- 0.4 versus 4.2 + 0.5 mol/g villi protein; P < 0.001) was less than that of L-arginine. This study describes a simple technique using placental explants to determine relative rates of uptake of substrate amino acids throughout gestation. (+info)Cross-reaction with luteinizing hormone beta-core is responsible for the age-dependent increase of immunoreactive beta-core fragment of human chorionic gonadotropin in women with nonmalignant conditions. (5/497)
BACKGROUND: The beta-core fragment of human chorionic gonadotropin (hCGbetacf), also termed "beta-core" and urinary gonadotropin peptide (UGP), has been reported to be present in the urine of healthy women and to increase in concentration after menopause. This could reflect cross-reaction with the equivalent metabolite of luteinizing hormone (LH), the beta-LH-core. METHODS: We measured immunoreactive LH, hCG, free alpha-subunit, and free beta-subunit hCG (hCGbeta), as well as beta-core, using the S504 RIA and Triton UGP enzyme immunoassay in 274 urine samples from women with nonmalignant gynecological conditions. The molar cross-reaction of each assay with purified beta-LH-core was determined. RESULTS: Cross-reaction with beta-LH-core was 100% in the LH and the S504 beta-core assay, 5% in the Triton UGP assay, and <0.1% in the hCG, free alpha-subunit, and free hCGbeta assays. Median urine concentrations of all analytes showed an age-dependent increase. LH and free alpha-subunit concentrations were approximately 10(3) pmol/mol creatinine; hCG and S504 beta-core were approximately 10(2) pmol/mol creatinine; free hCGbeta and Triton UGP beta-core were in the tens of pmol/mol creatinine. The S504 beta-core concentrations were 10% of those of LH. S504 beta-core was strongly correlated with LH, but not with hCG or with free hCGbeta (LH, r2 = 0.45; hCG, r2 = 0.26; free hCGbeta, r2 = 0.03). The concentrations of beta-core detected by the Triton UGP assay, which has a 5% cross-reaction with beta-LH-core, were 2% of LH and 5% of the S504 beta-core concentrations. Triton UGP values correlated strongly with LH concentrations, but less well with S504 beta-core, intact hCG, and free hCGbeta (LH, r2 = 0.44; S504 beta-core, r2 = 0.33; hCG, r2 = 0.32; free hCGbeta, r2 = 0.19). CONCLUSIONS: Immunoreactive beta-core in women free of malignancies reflects cross-reaction with concentrations of the metabolite of LH, beta-LH-core, within the health-related reference interval. (+info)Perinatal outcome in pregnancies with a positive serum screening for Down's syndrome due to elevated levels of free beta-human chorionic gonadotropin. (6/497)
OBJECTIVE: To evaluate the potential clinical use of maternal serum free beta-human chorionic gonadotropin (beta-hCG) and uterine artery Doppler investigation to screen for placenta-related adverse outcome in pregnancies at positive risk for Down's syndrome at 15-18 weeks. DESIGN: A cohort of 329 consecutive pregnant women with a singleton viable pregnancy and a positive risk for Down's syndrome was retrospectively investigated. This group was obtained from an unselected population of 3952 women attending the same hospital over a 2-year period. Using the results of this first analysis, we selected a group of 26 women with unexplained high levels of free beta-hCG and followed them prospectively with monthly ultrasound and uterine artery Doppler examinations. RESULTS: In the retrospective cohort, risk ratios stratified for maternal serum beta-hCG multiple of the median (MoM) values indicated that the highest incidence of adverse pregnancy outcome was in those women with values of > or = 5.0. In the prospective study, pregnancy outcome was complicated by uteroplacental disorders in eight cases. Analysis of the Doppler investigation indicated that, in women with a very high level of hCG, an abnormally high uterine artery pulsatility index (PI) had lower sensitivity and negative predictive value than early diastolic notch, whereas the specificity and positive predictive value were higher for a high uterine artery PI. CONCLUSIONS: These findings suggest an association between a high level of maternal serum beta-hCG at 15-18 weeks, the presence of an early diastolic notch in the uterine artery flow velocity waveform and adverse pregnancy outcome due to abnormal development of the uteroplacental circulation. Young women with an unexplained high beta-hCG level would benefit, apart from detailed sonography of the fetus and/or karyotyping, from uterine Doppler investigation and counselling about the follow-up and management of placenta-related pregnancy disorders. (+info)Arteriovenous malformation of mesosalpinx associated with a 'vanishing' ectopic pregnancy: diagnosis with three-dimensional color power angiography. (7/497)
We describe two cases of pelvic arteriovenous malformation diagnosed with the aid of three-dimensional color power angiography. In both cases, beta-human chorionic gonadotropin (beta-hCG) increased to significant levels (8413 and 1560 mIU/ml, respectively); however, neither an intrauterine nor an adnexal gestational sac could be found. In each case, we observed an adnexal mass with several tortuous areas exhibiting abundant turbulent flow. The diagnosis of arteriovenous malformation was made and further assessment by three-dimensional color power angiography and magnetic resonance imaging (MRI) was carried out. The complex vascular anatomy of arteriovenous malformation, including its feeding vessels and drainage, was clearly depicted by three-dimensional color power angiography and correlated well with magnetic resonance angiography. Levels of beta-hCG decreased in subsequent tests, and eventually became negative 2-3 months later without and intervention. We believe that an involutional ectopic pregnancy induced the rapid growth of the arteriovenous malformations within the mesosalpinx. Three-dimensional color power angiography can be performed quickly and easily, using existing ultrasound equipment. It improves our understanding of complicated vasculature, and thus is a useful adjunct to two-dimensional and color Doppler ultrasound in the diagnosis of arteriovenous malformation. (+info)Cervical pregnancy--a conservative stepwise approach. (8/497)
A case of cervical pregnancy resistant to intramuscular methotrexate therapy is presented, which was successfully treated by intra-arterial methotrexate followed by selective prophylactic hypogastric artery embolization to avoid aggravating the vaginal bleeding. It is suggested that, in cervical pregnancies in which fertility preservation is desired, a stepwise conservative approach should be applied before resorting to surgical intervention. (+info)The symptoms of choriocarcinoma can vary depending on the location and size of the tumor, but they may include:
* Abnormal vaginal bleeding
* Pelvic pain
* Abdominal pain
* Weakness and fatigue
* Shortness of breath
* Nausea and vomiting
If choriocarcinoma is suspected, a variety of tests may be performed to confirm the diagnosis. These may include:
* Ultrasound: This imaging test uses high-frequency sound waves to create pictures of the uterus and ovaries. It can help doctors identify any abnormal growths or tumors in the area.
* Hysteroscopy: This procedure involves inserting a thin, lighted tube through the cervix to visualize the inside of the uterus. Doctors may use hysteroscopy to collect samples of tissue for testing.
* Laparoscopy: This procedure involves making small incisions in the abdomen and using a thin, lighted tube to visualize the inside of the pelvis. Doctors may use laparoscopy to collect samples of tissue for testing or to remove any tumors that are found.
* Biopsy: In this test, doctors take a small sample of tissue from the uterus and examine it under a microscope for cancer cells.
If choriocarcinoma is confirmed, treatment may involve a combination of surgery, chemotherapy, and radiation therapy. The specific treatment plan will depend on the stage and location of the cancer, as well as the patient's overall health.
Prognosis for choriocarcinoma varies depending on the stage of the cancer when it is diagnosed. In general, the prognosis is good if the cancer is caught early and treated promptly. However, if the cancer has spread to other parts of the body (metastasized), the prognosis may be poorer.
It's important for women who have had a molar pregnancy or choriocarcinoma to follow up with their healthcare provider regularly to ensure that any remaining tissue is removed and to monitor for any signs of recurrence.
Chorionic gonadotropin beta
Glycoprotein hormones, alpha polypeptide
CGB2 (gene)
Gestational trophoblastic disease
Luteinizing hormone beta polypeptide
CGB1
FSHB
CGB5
Immunocontraception
CGB7
Follicle-stimulating hormone
Luteinizing hormone
Human chorionic gonadotropin
Pregnancy test
Ray Iles
Thyroid-stimulating hormone
List of MeSH codes (D06)
List of MeSH codes (D23)
Giant-cell carcinoma of the lung
List of MeSH codes (D12.644)
Gonadotropin
Fertile eunuch syndrome
Sp4 transcription factor
Nuggehalli Raghuveer Moudgal
Amyloid-beta precursor protein
Index of biochemistry articles
References - US SPR | CDC
New technologies permit safe abortion at less than six weeks' gestation and provide timely detection of ectopic gestation -...
Pregnyl®
(chorionic gonadotropin) for injection
Publication Detail
Biomarkers Search
Pregnancy Test - hCG Research at NIH - Office of NIH History and Stetten Museum
Luteinizing Hormone Deficiency: Practice Essentials, Background, Causes
Childhood Central Nervous System Germ Cell Tumors Treatment (PDQ®) (Health professionals) | OncoLink
MeSH Browser
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | National Institutes of Health (NIH)
NHANES 2001-2002:
Standard Biochemistry Profile Data Documentation, Codebook, and Frequencies
NICHD Contributions to Society | NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development
bHCG
- Early...
Placenta-associated adverse pregnancy outcomes in women experiencing mild or severe hyperemesis gravidarum - a systematic...
Reversible immunocontraception in male monkeys immunized with eppin - PubMed
MH DELETED MN ADDED MN
DeCS
MeSH Browser
WikiGenes - Kestrone - (8S,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9...
hCG + β
Pesquisa | Prevenção e Controle de Câncer
Glioma; Glial Cell Tumors
Oman Medical Journal-Archive
Pharos : Target Details - CGB3
NDF-RT Code NDF-RT Name
Human papillomavirus vaccine overdose Human papillomavirus microbiology
DailyMed - CHORIONIC GONADOTROPIN kit
Browsing BIO Faculty Scholarship by Author "Ward, Darrell N."
MESH TREE NUMBER CHANGES - 2003 MeSH
Unique beta subunit2
- The unique beta subunit determines LH immunologic and biologic activity. (medscape.com)
- Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. (nih.gov)
Hormones5
- The beta subunits of these hormones differ in amino acid sequence. (nih.gov)
- The alpha subunit of LH is biologically identical to 3 other hormones: FSH, thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). (medscape.com)
- The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). (nih.gov)
- The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. (nih.gov)
- The alpha sub-unit is essentially identical to the alpha sub- units of the human pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as to the alpha sub-unit of human thyroid-stimulating hormone (TSH), while the beta sub- units of these hormones differ. (colinfwatson.com)
Inhibin2
- Western blot analysis was used to examine the size heterogeneity of equine inhibin a- and [S-subunits. (wichita.edu)
- Inhibin , activin i hormon I ne utiču na genetičku aktivnost za proizvodnju beta podjedinice LH. (wikipedia.org)
Thyroid-stimula1
- The alpha subunit is essentially identical to the alpha subunits of the human pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as to the alpha subunit of human thyroid-stimulating hormone (TSH). (nih.gov)
Pituitary3
- The action of human chorionic gonadotropin (hCG) is virtually identical to that of pituitary LH, although hCG appears to have a small degree of FSH activity as well. (nih.gov)
- Luteinizing hormone (LH) is a peptide produced by the anterior pituitary, along with follicle-stimulating hormone (FSH), in response to gonadotropin-releasing hormone (GnRH) from the hypothalamus. (medscape.com)
- LH deficiency can also occur due to stress-related hypogonadotropic hypogonadism, LH subunit mutations, congenital pituitary hormone deficiency (CPHD), pituitary tumors, inflammation, vascular accidents, and pregnancy-related hemorrhagic shock (Sheehan syndrome). (medscape.com)
Polypeptide2
10,0002
- Each multiple-dose vial is only for use in one patient and contains 10,000 USP units of chorionic gonadotropin with dibasic sodium phosphate (4.4 mg) and monobasic sodium phosphate (5 mg). (nih.gov)
- Chorionic Gonadotropin for Injection, USP is available in multiple dose vials containing 10,000 USP units with accompanying Bacteriostatic Water for Injection for reconstitution. (nih.gov)
Glycoprotein hormone1
- This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). (nih.gov)
LUTEINIZING HORMONE5
- The best test they had in 1970 was an immunoassay that could measure hCG but could not distinguish between hCG and luteinizing hormone (LH), another of the human gonadotropins that shares its biological characteristics. (nih.gov)
- LH and hCG act via the luteinizing hormone chorionic gonadotropin receptor (LHCGR). (medscape.com)
- Its structure is similar to the beta subunit of LUTEINIZING HORMONE , except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. (nih.gov)
- Abstract We report here results of clinical trials on a birth control vaccine, consisting of a heterospecies human papillomavirus vaccine overdose of the beta subunit of human chorionic gonadotropin hCG associated noncovalently with the alpha subunit of ovine luteinizing hormone and conjugated to tetanus and diphtheria toxoids as carriers, that induces antibodies of high avidity K a approximately 10 10 M-1 against hCG. (malaimare.ro)
- This preparation of Human Luteinizing Hormone, Beta Subunit ( β -hLH) is isolated from highly purified, intact hLH and is provided as a powder, lyophilized from ammonium bicarbonate. (scrippslabs.com)
Injection2
- PREGNYL ® (chorionic gonadotropin) for injection is a sterile, dried powder for intramuscular injection after reconstitution. (nih.gov)
- Gonal-f ® (follitropin alfa for injection) is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the α- and β-subunits. (rxlist.com)
Antibodies1
- When injected as a vaccine to a non-pregnant woman, this Beta HCG sub unit combined with tetanus toxoid develops antibodies against tetanus and HCG so that if a woman's egg becomes fertilized, her own natural HCG will be destroyed rendering her permanently infertile, the bishops explain. (wordpress.com)
Identical1
- Equine chorionic gonadotropin (eCG) and lutropin (eLH) are composed of a- and P-subunits with an identical amino acid sequence but show different biological activities. (wichita.edu)
Biological7
- This study indicates that short peptide segments, in addition to full-length AFP, and domain and subdomain fragments of AFP, could be employed as functional agents to help unravel the complexity of biological roles ascribed to human AFP. (atlasgeneticsoncology.org)
- Description: A sandwich quantitative ELISA assay kit for detection of Mouse Platelet Derived Growth Factor Subunit B (PDGFB) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. (scalegen.com)
- Description: A competitive ELISA for quantitative measurement of Rat Platelet-derived growth factor subunit B(PDGFB) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. (scalegen.com)
- Description: A competitive ELISA for quantitative measurement of Human Claudin 18(CLDN18) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. (resourcerecovery.be)
- Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Claudin 18 (CLDN18) in tissue homogenates, cell lysates and other biological fluids. (resourcerecovery.be)
- Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Claudin 18 (CLDN18) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (resourcerecovery.be)
- The in vivo biological activity of follitropin alfa has been calibrated against the first International Standard for Recombinant Human Follicle Stimulation Hormone established in 1995 by the Expert Committee on Biological Standards of the World Health Organization . (rxlist.com)
CONTRAINDICATIONS2
- Use hCG in conjunction with gonadotropin therapy only if the physician is experienced with infertility problems and is familiar with the criteria for patient selection, contraindications, warnings, precautions, and adverse reactions described in the package insert for gonadotropins. (nih.gov)
- HCG should be used in conjunction with human menopausal gonadotropins only by physicians experienced with infertility problems who are familiar with the criteria for patient selection, contraindications, warnings, precautions and adverse reactions described in the package insert for menotropins. (nih.gov)
Ovine2
- Theα subunit of ovine lutropin can be nicked with the endoproteinase Arg-C to give a single cleavage of the Arg46-Ser47 peptide bond. (wichita.edu)
- Ovine (o) and equine (e) LH alpha-subunits were reduced and reoxidized using conditions known to be effective for bovine and human alpha-subunits. (wichita.edu)
Serum2
- When no chorionic membrane with villi was seen in the curettings, postoperative serum levels of beta-human chorionic gonadotropin confirmed complete evacuation or diagnosed ectopic pregnancy. (nih.gov)
- The B·R·A·H·M·S hCG+β KRYPTOR test is an automated immunofluorescent assay for the quantitative determination of the concentration of hCG+β (human chorionic gonadotropin hormone and its free beta subunit) in human serum. (brahms.de)
Ovarian1
- Induction of ovulation and pregnancy in the anovulatory, infertile woman in whom the cause of anovulation is secondary and not due to primary ovarian failure, and who has been appropriately treated with human gonadotropins. (nih.gov)
Receptor1
- Ova beta podjedinica sadrži sekvencu aminokiselina koja pokazuje velike homologije sa beta podjedinicama horionski gonadotropin čovjeka i oba stimuliraju isti receptor. (wikipedia.org)
Urine1
- Chorionic gonadotropin is obtained from the human pregnancy urine. (nih.gov)
Amino acids3
- The alpha subunit is composed of 92 amino acids and is encoded on the long arm of chromosome 6. (medscape.com)
- The beta subunit is 121 amino acids and is encoded on the long arm of chromosome 19. (medscape.com)
- The α- and β-subunits have 92 and 111 amino acids , respectively, and their primary and tertiary structure are indistinguishable from those of human follicle stimulating hormone. (rxlist.com)
Protein4
- 15. Partial amino acid sequence of human plasma retinol-binding protein. (nih.gov)
- We included original, published, observational studies examining the association of first trimester pregnancy associated plasma protein-A (PAPP-A) and/or free β-human chorionic gonadotropin (free β-hCG) levels with GDM diagnosis. (nih.gov)
- jedna alfa i jedan beta podjedinica grade puni, funkcijski protein. (wikipedia.org)
- Description: Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. (resourcerecovery.be)
Superoxide dismutase1
- 16. The primary structure of human liver manganese superoxide dismutase. (nih.gov)
Diagnosis1
- Early termination combined with vaginal ultrasonography and follow-up with beta-human chorionic gonadotropin measurements allows diagnosis of early, unsuspected ectopic pregnancy. (nih.gov)
Pregnant1
- Nausea and vomiting in pregnancy (NVP) affects 50-80% of pregnant women and is correlated to the level of human chorionic gonadotropin (hCG). (biomedcentral.com)
Alpha and beta2
- LH is a glycoprotein dimer composed of 2 glycosylated noncovalently-linked subunits designated alpha and beta. (medscape.com)
- hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. (nih.gov)
Recombinant1
- Based on available data derived from physico-chemical tests and bioassays, follitropin alfa and follitropin beta, another recombinant follicle stimulating hormone product, are indistinguishable. (rxlist.com)
Tetanus1
- The bishops' statement notes that in the Philippines, Nicaragua, and Mexico, the tetanus vaccine was "laced with Beta human chorionic gonadotropin (b-HCG) sub unit … to vaccinate women against future pregnancy. (wordpress.com)
Pregnancy2
- Scientists did know that the human body secretes hCG only during pregnancy or during certain kinds of cancers. (nih.gov)
- NICHD investigators identified the beta subunit of human chorionic gonadotropin (hCG) as the earliest marker of pregnancy, leading to the development and subsequent commercialization of the first home pregnancy test. (nih.gov)
Vaccine3
- This study presents evidence of the feasibility of a vaccine human papillomavirus vaccine overdose control of human fertility. (malaimare.ro)
- Dar daca Dom-nul asa a binevoit ca noi sa suferim aceste vre-muri, apoi tre-buie sa ne supunem si sa human papillomavirus vaccine overdose cu bucurie toate cele ce vin asupra noas-tra, ca din mana lui Dum-nezeu, si nu a vra-j-ma-su-lui. (malaimare.ro)
- Daca mama va lasa copilul sa fie vac-ci-nat, este human papillomavirus vaccine overdose si cum l-ar da la moarte. (malaimare.ro)
Tertiary structure1
- 11. Primary and tertiary structure of the principal human adenylate kinase. (nih.gov)
NICHD3
- Both young doctors arrived in Bethesda in 1970 and in the years they spent with the Reproductive Research Branch-first at the National Cancer Institute (NCI) and then at the National Institute for Child Health and Human Development (NICHD)-they found an active community for the study of reproductive endocrinology. (nih.gov)
- The mission of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is to lead research and training to understand human development, improve reproductive health, enhance the lives of children and adolescents, and optimize abilities for all. (nih.gov)
- Research conducted and funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) has helped save lives, improve wellbeing, and reduce societal costs associated with illness and disability. (nih.gov)
Preparation1
- Chorionic gonadotropin is a purified preparation composed of an alpha and a beta subunit. (nih.gov)
Research1
- NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
Similar1
- Su estructura es similar a la de la unidad beta de la LUTROPINA, excepto en los 30 aminoácidos adicionales del extremo carboxi con los residuos de carbohidratos asociados. (bvsalud.org)
Product1
- The major product of oLH alpha refolding was alpha-subunit monomer. (wichita.edu)
Child Health and Human Development1
- May 1963 - The Surgeon General appoints members of the National Advisory Child Health and Human Development (NACHHD) Council. (nih.gov)
Study1
- Human Chorionic Gonadotropin (hCG) was a fascinating hormone to study in 1970, partly because not much was known about its behavior or makeup. (nih.gov)
Development2
Cells1
- Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors. (uchicago.edu)