Chorion: The outermost extra-embryonic membrane surrounding the developing embryo. In REPTILES and BIRDS, it adheres to the shell and allows exchange of gases between the egg and its environment. In MAMMALS, the chorion evolves into the fetal contribution of the PLACENTA.Egg Proteins: Proteins which are found in eggs (OVA) from any species.Extraembryonic Membranes: The thin layers of tissue that surround the developing embryo. There are four extra-embryonic membranes commonly found in VERTEBRATES, such as REPTILES; BIRDS; and MAMMALS. They are the YOLK SAC, the ALLANTOIS, the AMNION, and the CHORION. These membranes provide protection and means to transport nutrients and wastes.Amnion: The innermost membranous sac that surrounds and protects the developing embryo which is bathed in the AMNIOTIC FLUID. Amnion cells are secretory EPITHELIAL CELLS and contribute to the amniotic fluid.Bombyx: A genus of silkworm MOTHS in the family Bombycidae of the order LEPIDOPTERA. The family contains a single species, Bombyx mori from the Greek for silkworm + mulberry tree (on which it feeds). A native of Asia, it is sometimes reared in this country. It has long been raised for its SILK and after centuries of domestication it probably does not exist in nature. It is used extensively in experimental GENETICS. (From Borror et al., An Introduction to the Study of Insects, 4th ed, p519)Allantois: An extra-embryonic membranous sac derived from the YOLK SAC of REPTILES; BIRDS; and MAMMALS. It lies between two other extra-embryonic membranes, the AMNION and the CHORION. The allantois serves to store urinary wastes and mediate exchange of gas and nutrients for the developing embryo.Labor, Obstetric: The repetitive uterine contraction during childbirth which is associated with the progressive dilation of the uterine cervix (CERVIX UTERI). Successful labor results in the expulsion of the FETUS and PLACENTA. Obstetric labor can be spontaneous or induced (LABOR, INDUCED).Vitelline Membrane: The plasma membrane of the egg.Placenta: A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).Egg Shell: A hard or leathery calciferous exterior covering of an egg.Oryzias: The only genus in the family Oryziinae, order BELONIFORMES. Oryzias are egg-layers; other fish of the same order are livebearers. Oryzias are used extensively in testing carcinogens.Oogenesis: The process of germ cell development in the female from the primordial germ cells through OOGONIA to the mature haploid ova (OVUM).Ovum: A mature haploid female germ cell extruded from the OVARY at OVULATION.Trophoblasts: Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA).Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Decidua: The hormone-responsive glandular layer of ENDOMETRIUM that sloughs off at each menstrual flow (decidua menstrualis) or at the termination of pregnancy. During pregnancy, the thickest part of the decidua forms the maternal portion of the PLACENTA, thus named decidua placentalis. The thin portion of the decidua covering the rest of the embryo is the decidua capsularis.Gene Amplification: A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the production of an RNA transcript of the entire repeating sequence of ribosomal RNA followed by the reverse transcription of the molecule to produce an additional copy of the original DNA sequence. Laboratory techniques have been introduced for inducing disproportional replication by unequal crossing over, uptake of DNA from lysed cells, or generation of extrachromosomal sequences from rolling circle replication.Aedes: A genus of mosquitoes (CULICIDAE) frequently found in tropical and subtropical regions. YELLOW FEVER and DENGUE are two of the diseases that can be transmitted by species of this genus.Insect Proteins: Proteins found in any species of insect.Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.Pharmacies: Facilities for the preparation and dispensing of drugs.Pharmacy: The practice of compounding and dispensing medicinal preparations.Education, Pharmacy: Formal instruction, learning, or training in the preparation, dispensing, and proper utilization of drugs in the field of medicine.Schools, Pharmacy: Educational institutions for individuals specializing in the field of pharmacy.Adrenergic alpha-Agonists: Drugs that selectively bind to and activate alpha adrenergic receptors.Community Pharmacy Services: Total pharmaceutical services provided to the public through community pharmacies.Warts: Benign epidermal proliferations or tumors; some are viral in origin.Medicine, Ayurvedic: The traditional Hindu system of medicine which is based on customs, beliefs, and practices of the Hindu culture. Ayurveda means "the science of Life": veda - science, ayur - life.Fingers: Four or five slender jointed digits in humans and primates, attached to each HAND.Malaysia: A parliamentary democracy with a constitutional monarch in southeast Asia, consisting of 11 states (West Malaysia) on the Malay Peninsula and two states (East Malaysia) on the island of BORNEO. It is also called the Federation of Malaysia. Its capital is Kuala Lumpur. Before 1963 it was the Union of Malaya. It reorganized in 1948 as the Federation of Malaya, becoming independent from British Malaya in 1957 and becoming Malaysia in 1963 as a federation of Malaya, Sabah, Sarawak, and Singapore (which seceded in 1965). The form Malay- probably derives from the Tamil malay, mountain, with reference to its geography. (From Webster's New Geographical Dictionary, 1988, p715 & Room, Brewer's Dictionary of Names, 1992, p329)Condylomata Acuminata: Sexually transmitted form of anogenital warty growth caused by the human papillomaviruses.Blogging: Using an INTERNET based personal journal which may consist of reflections, comments, and often hyperlinks.Neanderthals: Common name for an extinct species of the Homo genus. Fossils have been found in Europe and Asia. Genetic evidence suggests that limited interbreeding with modern HUMANS (Homo sapiens) took place.Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)Urinary Tract Infections: Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.Bronchitis, Chronic: A subcategory of CHRONIC OBSTRUCTIVE PULMONARY DISEASE. The disease is characterized by hypersecretion of mucus accompanied by a chronic (more than 3 months in 2 consecutive years) productive cough. Infectious agents are a major cause of chronic bronchitis.Bronchitis: Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.Dihydropteroate Synthase: An enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. EC 2.5.1.15.Sulfadimethoxine: A sulfanilamide that is used as an anti-infective agent.Unconscious (Psychology): Those forces and content of the mind which are not ordinarily available to conscious awareness or to immediate recall.Fossil Fuels: Any combustible hydrocarbon deposit formed from the remains of prehistoric organisms. Examples are petroleum, coal, and natural gas.Factor Analysis, Statistical: A set of statistical methods for analyzing the correlations among several variables in order to estimate the number of fundamental dimensions that underlie the observed data and to describe and measure those dimensions. It is used frequently in the development of scoring systems for rating scales and questionnaires.Earth (Planet): Planet that is the third in order from the sun. It is one of the four inner or terrestrial planets of the SOLAR SYSTEM.Evolution, Planetary: Creation and development of bodies within solar systems, includes study of early planetary geology.Vocabulary: The sum or the stock of words used by a language, a group, or an individual. (From Webster, 3d ed)Unconsciousness: Loss of the ability to maintain awareness of self and environment combined with markedly reduced responsiveness to environmental stimuli. (From Adams et al., Principles of Neurology, 6th ed, pp344-5)

Mrj encodes a DnaJ-related co-chaperone that is essential for murine placental development. (1/662)

We have identified a novel gene in a gene trap screen that encodes a protein related to the DnaJ co-chaperone in E. coli. The gene, named Mrj (mammalian relative of DnaJ) was expressed throughout development in both the embryo and placenta. Within the placenta, expression was particularly high in trophoblast giant cells but moderate levels were also observed in trophoblast cells of the chorion at embryonic day 8.5, and later in the labyrinth which arises from the attachment of the chorion to the allantois (a process called chorioallantoic fusion). Insertion of the ROSAbetageo gene trap vector into the Mrj gene created a null allele. Homozygous Mrj mutants died at mid-gestation due to a failure of chorioallantoic fusion at embryonic day 8.5, which precluded formation of the mature placenta. At embryonic day 8.5, the chorion in mutants was morphologically normal and expressed the cell adhesion molecule beta4 integrin that is known to be required for chorioallantoic fusion. However, expression of the chorionic trophoblast-specific transcription factor genes Err2 and Gcm1 was significantly reduced. The mutants showed no abnormal phenotypes in other trophoblast cell types or in the embryo proper. This study indicates a previously unsuspected role for chaperone proteins in placental development and represents the first genetic analysis of DnaJ-related protein function in higher eukaryotes. Based on a survey of EST databases representing different mouse tissues and embryonic stages, there are 40 or more DnaJ-related genes in mammals. In addition to Mrj, at least two of these genes are also expressed in the developing mouse placenta. The specificity of the developmental defect in Mrj mutants suggests that each of these genes may have unique tissue and cellular activities.  (+info)

Canine preprorelaxin: nucleic acid sequence and localization within the canine placenta. (2/662)

Employing uteroplacental tissue at Day 35 of gestation, we determined the nucleic acid sequence of canine preprorelaxin using reverse transcription- and rapid amplification of cDNA ends-polymerase chain reaction. Canine preprorelaxin cDNA consisted of 534 base pairs encoding a protein of 177 amino acids with a signal peptide of 25 amino acids (aa), a B domain of 35 aa, a C domain of 93 aa, and an A domain of 24 aa. The putative receptor binding region in the N'-terminal part of the canine relaxin B domain GRDYVR contained two substitutions from the classical motif (E-->D and L-->Y). Canine preprorelaxin shared highest homology with porcine and equine preprorelaxin. Northern analysis revealed a 1-kilobase transcript present in total RNA of canine uteroplacental tissue but not of kidney tissue. Uteroplacental tissue from two bitches each at Days 30 and 35 of gestation were studied by in situ hybridization to localize relaxin mRNA. Immunohistochemistry for relaxin, cytokeratin, vimentin, and von Willebrand factor was performed on uteroplacental tissue at Day 30 of gestation. The basal cell layer at the core of the chorionic villi was devoid of relaxin mRNA and immunoreactive relaxin or vimentin but was immunopositive for cytokeratin and identified as cytotrophoblast cells. The cell layer surrounding the chorionic villi displayed specific hybridization signals for relaxin mRNA and immunoreactivity for relaxin and cytokeratin but not for vimentin, and was identified as syncytiotrophoblast. Those areas of the chorioallantoic tissue with most intense relaxin immunoreactivity were highly vascularized as demonstrated by immunoreactive von Willebrand factor expressed on vascular endothelium. The uterine glands and nonplacental uterine areas of the canine zonary girdle placenta were devoid of relaxin mRNA and relaxin. We conclude that the syncytiotrophoblast is the source of relaxin in the canine placenta.  (+info)

Formation of mature egg envelope subunit proteins from their precursors (choriogenins) in the fish, Oryzias latipes: loss of partial C-terminal sequences of the choriogenins. (3/662)

The inner layer of egg envelope of the medaka, Oryzias latipes, comprises two major groups of glycoprotein subunits, ZI-1,2 and ZI-3. Their precursor proteins, choriogenin H (Chg H) and choriogenin L (Chg L), respectively, are synthesized in spawning female liver. In the present study, the primary structures of the precursors and the corresponding mature subunits were compared by peptide mapping and amino acid sequencing to find what difference in their molecular structures is relevant to the assembly of the soluble precursors into the insoluble inner layer. The primary structures of the solubilized subunits were mostly identical to those of the respective precursors, but they lacked C-terminal partial sequences that their precursors possessed, namely, ZI-1,2 subunit was shorter than Chg H by 34 amino acid residues and ZI-3 was shorter than Chg L by 27 residues. In addition, a consensus amino acid sequence, Arg-Lys-X-Arg, was found at the putative cleavage sites in the C-terminal region of the precursors. It is conjectured that the truncation of the precursor proteins is prerequisite for formation of mature chorion subunit proteins and their assembly into chorion.  (+info)

CD9 is expressed in extravillous trophoblasts in association with integrin alpha3 and integrin alpha5. (4/662)

The CD9 molecule is a 24-27 kDa cell surface glycoprotein, which may be related to Schwann cell migration and adhesion. In this study, we examined the expression of CD9 in human extravillous trophoblasts, which invade into the endometrium during implantation and placentation. CD9 was detected immunohistochemically on the extravillous trophoblasts in the cell columns of first trimester placentae, but not on villous trophoblasts. In the second and third trimester, CD9 was highly expressed on the extravillous trophoblasts in the basal plate of placentae, and in the chorion laeve in the fetal membrane of term placentae. The molecular mass of CD9 in the chorion laeve was shown to be 27 kDa by Western blotting. The mRNA of CD9 was also detected in the chorion laeve by reverse transcription-polymerase chain reaction (RT-PCR). Proteins were purified from chorion laeve by affinity chromatography with anti-integrin alpha3 and alpha5 monoclonal antibodies and Western blotting, revealed that CD9 was associated with both integrins. These findings indicate that CD9 is a differentiation-related molecule present in the extravillous trophoblasts. Since it is associated with integrin alpha5 which has been proposed to regulate trophoblast invasion, CD9 may be implicated in trophoblast invasion at the feto-maternal interface.  (+info)

Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. (5/662)

Members of the BMP family of signaling molecules display a high conservation of structure and function, and multiple BMPs are often coexpressed in a variety of tissues during development. Moreover, distinct BMP ligands are capable of activating common pathways. Here we describe the coexpression of two members of the 60A subfamily of BMPs, Bmp5 and Bmp7, at a number of different sites in the embryo from gastrulation onwards. Previous studies demonstrate that loss of either Bmp5 or Bmp7 has negligible effects on development, suggesting these molecules functionally compensate for each other at early stages of embryonic development. Here we show this is indeed the case. Thus we find that Bmp5;Bmp7 double mutants die at 10.5 dpc and display striking defects primarily affecting the tissues where these factors are coexpressed. The present analysis also uncovers novel roles for BMP signaling during the development of the allantois, heart, branchial arches, somites and forebrain. Bmp5 and Bmp7 do not appear to be involved in establishing pattern in these tissues, but are instead necessary for the proliferation and maintenance of specific cell populations. These findings are discussed with respect to potential mechanisms underlying cooperative signaling by multiple members of the TGF-beta superfamily.  (+info)

A monoclonal antibody against chorion proteins of the sea bass Dicentrarchus labrax (Linnaeus, 1758): studies of chorion precursors and applicability in immunoassays. (6/662)

The monoclonal antibody DLE7 was obtained against 44- to 50-kDa polypeptides solubilized from the vitelline envelope of the Mediterranean sea bass Dicentrarchus labrax. In Western blot analysis of chorion lysates it recognized cross-reactive bands at 44 kDa, 48 kDa, and 110 kDa. Previous affinity blotting with concanavalin-A showed that most of solubilized bands were glycosylated. Enzymatic deglycosylation of chorion proteins followed by Western blot analysis with DLE7 showed that the 48-kDa and 110-kDa antigens were differentially affected by endoglycosidase-F treatment. When DLE7 was employed in immunofluorescence analysis, isolated chorions and ovarian cryosections stained intensely. Positivity was also observed in liver cryosections of spawning females but not in liver of males and nonspawning females. To study the origin and delivery of chorion proteins, DLE7 was used in Western blot analysis of liver homogenates and blood serum of spawning females. Cross-reacting bands were detected in liver (90 kDa) and serum (180 kDa, 50 kDa). DLE7 was also used for the first time to set up an indirect ELISA assay to detect egg antigens in the blood of egg-producing females, raising the possibility of using DLE7 as a female-specific marker of spawning for sea bass.  (+info)

Tissue plasminogen activator and its receptor in the human amnion, chorion, and decidua at preterm and term. (7/662)

The plasminogen activator system consists of two proteins: tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), which act upon their specific receptors to generate plasmin from plasminogen located on the cell surface. Plasmin then acts directly and indirectly to degrade the components of the extracellular matrix (ECM). This process is likely to be important in the normal turnover of the ECM of fetal membranes and in its premature weakening in preterm premature rupture of the fetal membranes. Quantitative Northern analysis and in situ hybridization have shown that the decidua expresses mRNA for tPA. However, the immunolocalized tPA protein was most strongly associated with the amnion and chorion, as was its receptor annexin II, suggesting that the amnion and chorion are the targets for decidual tPA. At term, decidual tPA expression was unaffected by labor, and the tPA receptor was elevated both before and after labor. At preterm, the converse was found: decidual tPA expression was significantly (p < 0. 05) up-regulated by labor, but the tPA receptor was not. The results suggest that the generation of plasmin at term would be controlled by an increased concentration of the tPA receptor in the amnion and chorion, whereas at preterm a pathological increase in plasmin would be generated by an overexpression of tPA, initiated by labor.  (+info)

Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. (8/662)

A large body of experimental evidence supports the participation of two groups of extracellular proteases, matrix metalloproteinases (MMPs), and plasminogen activators/plasmin, in tissue remodeling in physiological and pathological invasion. In the late mouse placenta, several tissue remodeling and cell invasion processes take place. Spongiotrophoblast migration into maternal decidua, as well as decidual extracellular matrix remodeling require the coordinated action of extracellular proteolytic enzymes. Via Northern and in situ hybridization, we have analyzed the spatio-temporal expression patterns of members of the MMP family (stromelysin-3, gelatinases A and B), as well as their inhibitors TIMP-1, -2 and -3 in late murine placenta (days 10.5 to 18.5 of gestation). Gelatinase activity in placental extracts was assessed by substrate zymography. Gelatinase A and stromelysin-3 were found to be prominently expressed in decidual tissue; shortly after midpregnancy, the decidual expression patterns of gelatinase A and stromelysin-3 became overlapping with each other, as well as with the expression domain of TIMP-2. On the other hand, gelatinase B transcripts were expressed only by trophoblast giant cells at day 10.5, and were downregulated at later stages. TIMP-1 and TIMP-3 transcripts were detected in decidual periphery at day 10.5, while later the expression was restricted to the endometrial stroma and spongiotrophoblasts, respectively. The areas of stromelysin-3 expression were the same (giant trophoblasts) or adjacent (decidua) to those where urokinase (uPA) transcripts were detected, suggesting a possible cooperation between these proteinases in placental remodeling. We generated mice doubly deficient for stromelysin-3 and uPA, and report here that these mice are viable and fertile. Furthermore, these animals do not manifest obvious placental abnormalities, thereby suggesting the existence of compensatory/redundant mechanisms involving other proteolytic enzymes. Our findings document the participation of MMPs and their inhibitors in the process of late murine placenta maturation, and warrant the characterization of other members of the MMP family, like membrane type-MMPs, in this process.  (+info)

Chorion, the brand licensing company that owns the rights to Noddy, has strengthened its marketing team ahead of a major push into the US.. The company, which also owns the rights to the works of Agatha Christie, has moved Lori Heiss, the head of marketing in the US, to the same role in Europe and has appointed Monika Salazar to replace her. Salazar, who will have the title of vice president for marketing US, joins from Viz Media in San Francisco, where she was director of brand marketing. She has also held a variety of marketing roles across the entertainment and fast food sectors.. It has also appointed Pamela Ferris as vice president for licensing. She joins from New York-based GT Brands, where she was head of licensing and consumer products.. The changes to the marketing team follow Chorions acquisition of New York based Silver Lining Productions, which will specialise in developing and producing TV content using Chorions stable of brands. Both Ferris and Salazar will be based in the New ...
Get information, facts, and pictures about Chorion at Encyclopedia.com. Make research projects and school reports about Chorion easy with credible articles from our FREE, online encyclopedia and dictionary.
Amyloid fibril formation propensity is inherent into the hexapeptide tandemly repeating sequence of the central domain of silkmoth chorion proteins of the A-family Journal Article ...
The potential of the developing zebrafish model for toxicology and drug discovery is limited by inefficient approaches to manipulating and chemically exposing zebrafish embryos-namely, manual placement of embryos into 96- or 384-well plates and exposure of embryos while still in the chorion, a barrier of poorly characterized permeability enclosing the developing embryo. We report the automated dechorionation of 1600 embryos at once at 4 h postfertilization (hpf) and placement of the dechorionated embryos into 96-well plates for exposure by 6 hpf. The process removed ≥95% of the embryos from their chorions with 2% embryo mortality by 24 hpf, and 2% of the embryos malformed at 120 hpf. The robotic embryo placement allocated 6-hpf embryos to 94.7% ± 4.2% of the wells in multiple 96-well trials. The rate of embryo mortality was 2.8% (43 of 1536) from robotic handling, the rate of missed wells was 1.2% (18 of 1536), and the frequency of multipicks was ,0.1%. Embryo malformations observed at 24 hpf ...
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Enzyme in Fishes:. The chorion contains an enzyme known as chorionase. The chorion also resists digestion by trypsin and pepsin, it possesses pseudo-keratin. The hardening of chorion is due to the enzyme in the perivitelline fluid. Ca++ affects the enzyme rather than chorion itself. Hardening resulted from oxidation of SH to SS groups by means of aldehydes produced by polysaccharide with a glycol groups. Hatching enzyme works best under alkaline condition, pH 7.2-9.6 and temperature of 14-20 °C. Acetyl cholinesterase, the enzyme associated with nervous stimulation of the muscles, has been detected on 10th day after fertilization in Salmo gairdneri eggs. In the eye stage increase in activity is almost coinciding with the development of excitable tissue. Ornithine transcarbamylase and arginase of the five O-U cycle enzymes were reported in the egg of Salmo which were capable of excreting nitrogen.. Metabolism of Nitrogenous Wastes in Fishes:. Metabolism and nitrogenous wastes in the eggs and ...
Fetal Model Soft, Placenta, Cord, Chorion and Amniotic Sac is a popular tool for childbirth educators and midwives.. The Fetal Model represents an average-sized full-term baby. Made of soft, yet durable cloth, the body flexes to show all presentations and positions.. The Fetal Model:. ...
4.30pm: Chorion, the media group that owns the rights to the Noddy and Mr Men characters, has added the creations of a number of American childrens writers to its business. By Chris Tryhorn.
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Taking a sample for cytogenetic chorion and fetal karyotyping. Can be performed transcervically or transabdominally.Being an invasive technique, it is
Egg: This egg sometimes appears pink and furry (Plate A), and close examination indicates it has a fine carpet of hairs on the chorion, but other eggs have a clear, glassy chorion (Plate A1). As the embryo develops, the black pigmented expansions on the dorsal finfold thread can be seen through the chorion (B). The egg takes up to 12 days to hatch (24°C). Unfortunately in captive conditions the egg often fails to hatch. Larva: At hatching the impressive larva has well developed eyes and a functional mouth (C). Myomeres are very fine and difficult to count in the larva, but appear to be about 90. Note the additional finger at the tip of each elongate pelvic fin ray, which has been seen in several specimens. C: NH (9 days PC). This egg was uncommon, which is not surprising as regalecids are open ocean fishes, and rarely seen (Heemstra 1986). Nevertheless my plankton samples have yielded, on average, 2 eggs per year. Ten larvae hatched from these eggs, have been barcoded, and match the barcode of ...
Gene target information for Cp38 - Chorion protein 38 (fruit fly). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
Neon Chorion Hotels in Chania in Greece. Discover the best Neon Chorion Chania hotels and get the Best Rates Guaranteed for Neon Chorion Accommodation in Hotels, Rooms to Let and Apartments at Greece.com.
Placenta, Cord, Amnion, Chorion Model - $89 A great teaching tool, this model of the placenta, cord, amnion, and chorion is perfect for childbirth education courses. Visit Cascade HealthCare Products secure Website to view our complete selection of educational materials for childbirth educators and professionals or to place an order.
TY - JOUR. T1 - Discovery and Characterization of Human Amniochorionic Membrane Microfractures. AU - Richardson, Lauren. AU - Vargas, Gracie. AU - Brown, Tyra. AU - Ochoa, Lorenzo. AU - Sheller-Miller, Samantha. AU - Saade, George. AU - Taylor, Robert N.. AU - Menon, Ramkumar. PY - 2017/12/1. Y1 - 2017/12/1. N2 - This study obtained visual evidence of novel cellular and extracellular matrix-level structural alterations in term and preterm human fetal amniochorionic membranes. Amniochorions were collected from term cesarean (not in labor) or vaginal (labor) deliveries, preterm premature rupture of membranes, and spontaneous preterm birth. To determine the effect of oxidative stress on membranes at term or preterm labor, term not in labor samples in an organ explant culture in vitro were exposed to cigarette smoke extract. Tissues were imaged using multiphoton autofluorescence and second harmonic generation microscopy. Images were analyzed using ImageJ and IMARIS software. Three-dimensional ...
Maternal immunoglobulin-G (IgG) is known to be transported across the placental syncytiotrophoblast during the period when the human fetus is incapable of manufacturing these defensive molecules. In this study we investigated the possible role of the amniochorion, that surrounds the amniotic cavity in which the fetus lies, in the transfer of immunoglobulin. Endogenous IgG was localised in the amniochorion by confocal immunofluorescence microscopy and by ultrastructural labelling of ultrathin frozen tissue sections using the protein A-gold technique. Immunoreactivity was identified in the extracellular matrix tissues and necrotic amniotic epithelial cells. Healthy amniotic epithelial cells and cytotrophoblast cells of the chorion laeve were devoid of endogenous IgG. These results suggest a possible nonspecific paracellular transport pathway between cytotrophoblast cells, which may conceivably contribute to the acquisition of passive immunity by the fetus, and offer a rational explanation for the ...
The Fetal Model, Placenta, Cord, Chorion and Amniotic Sac is a popular tool for childbirth educators. Paired with a Vinyl Pelvic Model or Cloth Pelvic Model it is ideal for demonstrating labour and birth. See below for more details. ...
Ive seen several offhand remarks that embryo chorions can be cleared using halocarbon oil. Is this true and, if so, what is a protocol for doing so? Thanks Scott Rifkin ...
Im afraid I have bad news. Chorion can categorically confirm that it does not hold the rights in this series, nor has it been able to identify who exactly does have the rights in this series. The Chorion legal team have invested a huge amount of time into investigating this matter and have been very thorough. We have identified that it was originally produced by the Portman Group under license from Family Film AG and Copyright Promotions (who, in turn, jointly acquired the rights from Darrell Waters Limited). We understand that Family Film AG became part of the Portman Group which is, we understand, now part of the Zenith Group. However, it is impossible for Chorion to identify whether the rights in this series were passed on from Family Film AG to the Portman Group, or from the Portman Group to Zenith. Please remember that this series was produced 30 years ago and that the initial production company no longer exists ...
Rats were observed by using a modified hot plate test before and at different times after formalin injection. Consequently, it calls for mapping the lectin presence in tumours. This supports the usefulness of the PO and TO concepts in describing AH professions and may provide new clues for policy aiming to enhance job satisfaction, retention and career development. A 43-year-old man, with no family history of either condition, was identified as having isolated hypogonadotropic hypogonadism with syndactyly of the feet.. THP-1 cells became adherent to a substrate by incubation with the culture supernatant of IV-infected chorion cells, but not with that of amnion cells. Scientific research originating from Brazil appears to be rising in several medical fields. The injury to the vena cava was treated using a continuous stitch without the necessity of conversion to open surgery. Possible application of these strains as food and feed supplements is under investigation. This study investigated the ...
Stages in the Life of a Butterfly Egg Butterfly eggs consist of a hard-ridged outer layer of shell, called the chorion. This is lined with a thin coating of wax, which prevents the egg from drying out before the larva has had time to fully develop. Each egg contains a number of tiny funnel-shaped openings at one end, called micropyles; the purpose of these holes is to allow sperm to enter and fertilize the egg. Butterfly and moth eggs vary greatly in size between species, but they are all either spherical or ovate. Butterfly eggs have a hard outer shell. This protects the larva inside. The shell is called the chorion. Inside, the egg is lined with wax. This keeps the egg from drying out. Not all eggs are the same shape or size. Larva Larvae, or caterpillars, are multi-legged eating machines. They consume plantleaves and spend practically all of their time in search of food. As they mature their skin is shed several times Larvae have three body parts-head, thorax and abdomen. Even though the ...
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Choroid (?), a. [gr. ; chorion + form.] Anatomy|Anat. resembling the chorion; as, the choroid plexuses of the ventricles of the br...
J:31267 Spindle A, Sturm KS, Flannery M, Meneses JJ, Wu K, Pedersen RA, Defective chorioallantoic fusion in mid-gestation lethality of parthenogenone
Supportive Structures Certain structures develop to support, maintain, new life throughout pregnancy - Embryonic or fetal membrane (chorion and amnion) - Placenta - Umbilical cord
Embryology research. Researcher manipulating zebrafish (Danio rerio) embryos under a microscope. The outer layer of the embryo, the chorion, has been removed to allow the injection of fluorescent labels. The labels will be used to track cells through the development of the embryo. - Stock Image C019/7651
Egg: This egg has only been seen once, on 5th July 2009. Due to its size and reticulated shell pattern, it was instantly recognised as being new to this collection. The chorion had a fine hexagonal mesh, with a small vertical projection at each corner (Plate A1). On hatching, the oil globules had coelesced into 1, positioned adjacent to the anus of the larva. Incubation was about 40 hours. Larva: The 3-day larva has lightly pigmented, a partly developed mouth, and abundant yellow pigment in the finfolds (C). The distinguishing feature is the gut which terminates laterally, and not ventrally (C, arrowed). C: 3 days.. The identification is tentative but based on description of macrourid eggs given by Merrett (2006). Efforts to barcode this larva failed; more accurate identification must await further collections. ...
Based in Dublin, Ireland, Brown Bag Films is an animation studio that has been producing award-winning series and short movies since 1994. A couple of years ago, family entertainment company Chorion approached Brown Bag Films to discuss developing an animated series based on Ian Falconer s Olivia books. These beloved children s stories follow the adventures of a mischievous but lovable pig. When they were asked to work on the project, Brown Bag realized they had several challenges. First, they had to convince the books author that they could translate his characters to the small screen. They also had to find a way to produce the series in 3D.
Mr Tickle can never suppress an irresistible urge to tickle everyone within his reach, which, because of his extraordinarily long arms covers a very, very wide range. Hes a mischievous character but kind at heart and hes always willing to use those long arms of his to help people. He is part of the original Mr Men and Little Miss series of books created by Roger Hargreaves in 1971.. In 2011, Sanrio (the creators of Hello Kitty) acquired the licensing rights to the Mr Men and Little Miss characters from Chorion; Costumes With Character produce her exclusively for the license holders Sanrio. Mr Tickle is an oval, orange, inanimate, antron fleece covered character with long wiggly arms, a blue hat and a huge friendly smile.. Please Note: This specific costume is not for sale or hire. It is subject to copyright and is here for your inspiration only. ...
A grade 3 placenta is marked by the 39th week of pregnancy up to the due date, significant shadowing on the ultrasound and complete indentations of the chorionic plate known as cotyledons, according...
TY - JOUR. T1 - Angiogenic activity of multiple myeloma endothelial cells in vivo in the chick embryo chorioallantoic membrane assay is associated to a down-regulation in the expression of endogenous endostatin. AU - Mangieri, Domenica. AU - Nico, Beatrice. AU - Benagiano, Vincenzo. AU - De Giorgis, Michela. AU - Vacca, Angelo. AU - Ribatti, Domenico. PY - 2008/6. Y1 - 2008/6. N2 - We have attempted a fine characterization of the angiogenic response induced by multiple myeloma endothelial cells (MMEC) by using the chick embryo chorioallantoic membrane (CAM) assay and by reverse transcriptase-polymerase chain reaction (RT-PCR). Results showed that in the CAM assay MMEC induced an angiogenic response comparable to that of a well-known angiogenic cytokine, namely fibroblast growth factor-2 (FGF-2), while RT-PCR demonstrated that the expression of endostatin mRNA detected in MM treated CAM was significantly lower respect to control CAM. These data suggest that angiogenic switch in MM may involve ...
The chorioallantoic membrane - also called the chorioallantois or abbreviated to CAM - is a vascular membrane found in eggs of some amniotes, such as birds and reptiles. It is formed by the fusion of the mesodermal layers of two developmental structures: the allantois and the chorion.[1] In mammals, this structure forms the placenta. Three different layers compose the chorioallantoic membrane; these are called the chorionic epithelium, the mesenchyme and the allantoic epithelium. Blood capillaries and sinuses are found between epithelial cells of the chorionic layer, allowing close contact (within 0.2 μm) with air found in pores of the shell membrane of the egg.[2] As a result, the chorioallantoic membrane allows exchange of gases, such as oxygen, to developing embryos.[1] During embryonic development of birds, the chorioallantoic membrane also plays an essential role in bone formation by transporting calcium into the embryo from the eggshell.[1] Chorioallantoic membranes from developing ...
The majority of ovarian cancer patients present with advanced disease and despite aggressive treatment, prognosis remains poor. Significant improvement in ovarian cancer survival will require the development of more effective molecularly targeted therapeutics. Commonly, mouse models are used for the in vivo assessment of potential new therapeutic targets in ovarian cancer. However, animal models are costly and time consuming. Other models, such as the chick embryo chorioallantoic membrane (CAM) assay, are therefore an attractive alternative. CAM assays have been widely used to study angiogenesis and tumor invasion of colorectal, prostate and brain cancers. However, there have been limited studies that have used CAM assays to assess ovarian cancer invasion and metastasis. We have therefore developed a CAM assay protocol to monitor the metastatic properties of ovarian cancer cells (OVCAR-3, SKOV-3 and OV-90) and to study the effect of potential therapeutic molecules in vivo. The results from the CAM assay
Acetylcholinesterase Inhibitors Promote Angiogenesis in Chick Chorioallantoic Membrane and Inhibit Apoptosis of Endothelial Cells. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Angiogenic potential of the cerebrospinal fluid (CSF) of patients with high-grade gliomas measured with the chick embryo chorioallantoic membrane assay (CAM) ...
Shark (Sinica cetorhinus maximum) cartilage was extracted in 1 mol/L Gu-HCl guanidine. Two purified active proteins with apparent molecular weights of 15.2x103 Da and 8.0×103 Da (designated as Sp15 and Sp8, respectively) were obtained through ultrafiltration and Superdex 75 chromatography. The activities of the samples were studied in terms of their potential inhibition of vascular endothelial cell growth in vitro, of angiogenesis both in rabbit cornea and chick embryo chorioallantoic membrane (CAM) assay models in vivo, and of growth of transplanted S180 sarcoma in mice in vivo. The results showed that Sp15 expressed a typical lysozymatic activity up to 223,000 U/mg and its N-terminus was highly homologous to lysozymes of various mammalian origins. Sp15 exhibited a strong anti-angiogenic activity only in vitro, whereas Sp8 shared this effect both in vitro and in vivo. Both Sp15 and Sp8 provided an effective anti-tumor activity in mice bearing transplanted S180 sarcoma. These results suggest that Sp15
The aims of this work are to study the antitumor effect of the adeno-associated virus on the xenografted tumors of chick embryo chorioallantoic membrane and predict potential genes and biological pathways which are associated with renal cell carcinoma. The adeno-associated virus NT4-TAT-6 × His-VHLbeta was constructed and identified. Then, chick embryos with xenografted tumor were divided into three groups and respectively inoculated with rAAV/NT4-TAT-6 × His-VHLbeta (group A), empty virus (group B), and phosphate-buffered saline (group C, the control subject). Antitumor effect in each group was investigated by means of immunofluorescence observation. Genes interacted with von Hippel-Lindau were screened by Search Tool for the Retrieval of Interacting Genes/Proteins database, while pathway analysis were performed based on Kyoto Encyclopedia of Genes and Genomes. The growth of xenografted tumors inoculated with recombinant adeno-associated virus was slower than the control subjects. The tumor ...
A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion.
A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion.
The authors studied the specific tumor antigen in Crockers sarcoma of mice and M-1 sarcoma of rats as well as in heterotransplants of these tumors on the chorioallantoic membrane of the developing...
A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Therapeutic regulation of tissue vascularization has appeared as an attractive approach to treat a number of human diseases. In vivo neovascularization assays that reflect physiological and pathological formation of neovessels are important in this effort. In this report we present an assay where the effects of activators and inhibitors of angiogenesis can be quantitatively and qualitatively measured. A provisional matrix composed of collagen I and fibrin was formed in a plastic cylinder and implanted onto the chick chorioallantoic membrane. A nylon mesh separated the implanted matrix from the underlying tissue to distinguish new from pre-existing vessels. Vascularization of the matrix in response to fibroblast growth factor-2 or platelet-derived growth factor-BB was scored in a double-blinded manner, or vessel density was measured using a semi-automated image analysis procedure. Thalidomide, fumagillin, U0126 and TGFβ inhibited neovessel growth while hydrocortisone exerted a negative and ...
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Free, official info about 2015 ICD-9-CM diagnosis code 762.8. Includes coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion info.
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The extra-placental gestational membranes secrete cytokines in response to bacteria and other infectious agents, with potentially adverse consequences for pregnancy. The present study used lipopolysaccharide (LPS) as a prototype endotoxin to investigate the pattern of stimulated cytokine release from the amniotic and choriodecidual sides of full-thickness human gestational membranes in a two-compartment tissue culture system. Gestational membranes were collected from healthy non-laboring caesarean deliveries at term. Full-thickness membranes from each placenta were cut into pieces, mounted on Transwell frames, and placed in culture wells to create a two-compartment culture with the gestational membranes serving as the barrier between compartments. The LPS (100 ng/ml) was added to the amniotic, choriodecidual or both chambers of the culture, and cytokines were assayed in the medium of the amniotic and choriodecidual chambers after 8 h of LPS exposure. Cytokine concentrations were analyzed by two-way
This stock medical exhibit features normal fetal membrane anatomy during pregnancy. It reveals a sagittal cut-away view of a full term pregnant abdomen with fetus shown in-utero. A blue colored membranous capsule is shown surrounding the fetus. Additionally, a detailed section through the membrane identifies and labels the amnion, chorion, uterus and decidua.
This stock medical exhibit features normal fetal membrane anatomy during pregnancy. It reveals a sagittal cut-away view of a full term pregnant abdomen with fetus shown in-utero. A blue colored membranous capsule is shown surrounding the fetus. Additionally, a detailed section through the membrane identifies and labels the amnion, chorion, uterus and decidua.
The mechanisms responsible for the onset of labor in women are not completely understood. Growing evidence suggests that bacterial products such as endotoxin could stimulate monocytes or macrophages to produce inflammatory cytokines such as IL-1, TNF, IL-6 and IL-8, which in turn stimulate prostaglandin biosynthesis by amnion, chorion and decidua and result in the onset of labor. Amniotic fluid IL-6 could be a sensitive indicator for prospective diagnosis of acute histologic chorioamnionitis, so amniotic fluid IL-6 is considered as an important cytokine. IL-13 and TIMP-3, recently described, have been known to relate to IL-6. IL-13, a novel T-helper cell lymphokin, has been shown to upregulate IL-6 production in keratinocytes, endothelial cells and mesothelial cells, whereas it downregulates IL-6 production in human monocytes. Tissue inhibitor of metalloproteinase-3(TIMP-3), new type distinct from TIMP-1 and TIMP-2, is known to be stimulated by IL-6. In this study , we examined C3H pregnant mice ...
A human embryo of the fourth week. I, the chorion; 3, part of the amnion; 4, umbilical vesicle with its long pedicle passing into the abdomen; 7, the heart; 8, the liver; 9, the visceral arch destined to form the lower jaw, beneath which are two other visceral arches separated by the branchial clefts; 10, rudiment of the upper extremity, 11, that of the lower extremity; 12, the umbilical cord; 15, the eye; 16, the ear; 17, cerebral hemispheres; 18, optic lobes, corpora quadrigemina.. ...
Anatomical structure in a pouch. Gestational sac: membranes enveloping the foetus or embryo. Composed by the fusion of chorion and amnion.
Eggs definition: initial phase in the bee life pattern, often laid because of the queen, could be the cylindrical egg 1/16in (1.6 mm) long; its enclosed with a flexible layer or chorion. It resembles…
This ectoparasitoid was attached to the chorion showing an incipient holdfast organelle (HFO) that goes through the perivitelline space as an anchorage to the embryo. This parasitoid divides using palintomic sporogenic divisions beneath the initial envelope of the trophont.. Body_trophont_length: 86 µm. ...
Detailed information on immature stages of Mutillidae is being acquired. However, Clausen (1940) noted that very little information was available regarding the form or habits of immature stages of this family. The egg of Mutilla sp (Williams 1919b) has been described as elongated and curved, with the chorion minutely granulated. It is placed transversely upon the dorsum of a Tiphia larva, between the 1st and 2nd thoracic segments. The point of larval feeding is ventral. Ferton stated that the egg of Stenomutilla argentata var. saundersivora Fer. is attached to the inner wall of the host cocoon. The early larval instars by 1940 had not been described for any species. The mature larva of M. glossinae has 11 pairs of spiracles, located on the 2nd and 3rd thoracic and the first 9 abdominal segments. The mandibles are 4-dentate, while those of M. lunata and M. attenuata are believed to be tridentate. The mature larvae of all species spin a cocoon within the cell, cocoon, or puparium of the host, ...
geth-sem-a-ne (Gethsemanei (for other spellings and accents see Thayer, under the word); probably from the Aramaic gath shemanim, "oil press"): Mentioned (Mt 26:36; Mk 14:32) as a place (chorion), margin "enclosed piece of ground," to which Jesus and the disciples retired after the last supper; in Jn 18:1 it is described as a "garden" (kepos), while Lk (22:40) simply says "place" (topos). From Jn 18:1 it is evident that it was across the Kidron, and from Lk 22:39, that it was on the Mount of Olives. Very possibly (Lk 21:37; 22:39) it was a spot where Jesus habitually lodged when visiting Jerusalem. The owner--whom conjecture suggests as Mary the mother of Mark--must have given Jesus and His disciples special right of entry to the spot. Tradition, dating from the 4th century, has fixed on a place some 50 yds. East of the bridge across the Kidron as the site. In this walled-in enclosure once of greater extent, now primly laid out with garden beds, by the owners--the Franciscans--are eight old ...
Mr Men owner Chorion has approached the private equity owner of Hit Entertainment about acquiring its Thomas the Tank Engine assets, according to the UKs Daily Telegraph newspaper.. The paper said other groups thought to be interested in buying the assets from Apax Partners included Viacom and Disney.. ...
Visit Cyprus. Best things to do in Ayia Napa, Larnaca, Limassol, Pissouri, Peyia, Paphos, Nicosia, Akrotiri, Neo Chorion, and Latchi are: Tombs of the Kings, Kato Paphos Archaeological Park, Nissi Beach, and Coral Bay. Travel Apr 27 - May 21.tagPlanMetaDescriptionTagHandler.CreatedByAUserFrom • Inspirock
Visit Cyprus. Best things to do in Neo Chorion are: Latchi Beach, Chrysorrogiatissa Monastery, Blue Lagoon, and Vouni Panayia Winery. See culture. Travel Sep 04 - Sep 11.tagPlanMetaDescriptionTagHandler.CreatedByAUserFrom • Inspirock
The overall objectives of this thesis were to develop a short-term culture system and to examine the effects of vitrification and short-term culture on the viability of fresh and vitrified bovine ovarian tissue and the follicles within. The first objective was to compare the health and development of preantral follicles in bovine ovarian tissue, as well as the neovascularization of these tissues, subjected to avian chorioallantoic membrane (CAM) culture with the traditional in vitro culture system. We hypothesized that the chorioallantoic membrane (CAM) of the chicken embryo is a more suitable culture system than traditional in vitro culture. Bovine ovaries were retrieved from a local abattoir and cortical pieces (1-2mm3) were randomly assigned to one of the following groups; control (fixed immediately), CAM or in in vitro culture. Ovarian tissue fragments from both groups were removed on D1, D3 and D5 of culture, fixed, sectioned (5μm) and stained with H&E. The numbers of healthy and ...
Introduction: The membrane-bound metalloproteinase aminopeptidase N (APN) is involved in several different cellular processes associated with the malignant phenotype. Furthermore APN has also been reported to have a functional role in tumor angiogenesis and there appear to be a strong correlation between the expression of APN and the invasive capacity of a numerous tumor cell types. The melphalan-derived prodrug melphalan-flufenamide (previously designated J1) can be activated by APN suggesting possible anti-angiogenic properties.. Experimental: A series of experiments were performed to evaluate the effects of melphalan-flufenamide on angiogenesis; cytotoxicity on bovine endothelial cells, the TCS Cellworks AngioKit model with human endothelial cells co-cultured with fibroblasts, the chicken embryo chorioallantoic membrane assay, and finally in vivo in mice using the Cultrex DIVAA angio-reactor assay.. Results: Melphalan-flufenamide displayed high cytotoxic activity against endothelial cells, ...
When a suspension of living adult chick leucocytes is placed in contact with the chorioallantoic membrane (CAM) of a developing chick embryo, a variable number of white focal lesions appear a few days later. The number of foci is positively correlated with the number of cells in the inoculum. The phenomenon is known to be an expression of an immunological reaction of the grafted cells against the host. F. M. Burnet and his colleagues have suggested that each focus results from the immunological activity of one and only one cell. If this presumption were confirmed the CAM system would gain in usefulness, in particular for the isolation of clones of immunologically competent cells. In the present work this single-hit hypothesis has been subjected to a specific test of its biometrical consequences. On the single-hit model the response should be proportional to the dose. Equivalently, on the logarithmic scale of measurement adopted in these experiments, the fitted dose-response line should show a ...
537 The expression of matrix metalloproteinases (MMPs) plays crucial roles in cancer progression and metastasis. This study is to clarify whether MMP associates with radiation-accelerated pulmonary metastasis of Lewis lung carcinoma (LLC-LM) in C57BL/6 mouse model. By using in vitro matrigel-coated Boyden chamber invasion assay, non-cytotoxic dose of radiation (7.5 Gy) significantly enhanced LLC-LM cell invasiveness. Irradiated LLC-LM cells showed the increased intravasation capability in the chicken chorioallantoic membrane assay. To test MMP family protein gene expression in irradiated LLC-LM cells, MMP-9 gene expression was significantly enhanced in both transcriptional and translational levels, so was the enzyme activity in the culture supernatant. The use of anti-sense MMP-9 oligonucleotides significantly inhibited the in vitro radiation-enhanced invasiveness. With 1 x 106 MMP-9 RNAi stably transfected LLC-LM cells injected subcutaneously in the right thighs of C57BL/6 mice and irradiated ...
Make note that in this term fetus, the chorion frondosum and the decidua basalis provide the fetal and maternal components of the placenta respectively. The chorion frondosum produces millions of villi that carry fetal capillaries so that the blood within them can come into close contact with maternal blood flowing through the intervillous spaces. Maternal and fetal blood do not mix in the placenta. The maternal blood flow into the placenta is through the decidua to bathe the chorionic villi and permit exchange of gasses, nutrients and metabolites between the maternal and fetal circulations. At birth, the placenta detaches from the wall of the uterus and follows the fetus. It is frequently referred to as the "afterbirth". ...
A swept source based Fourier domain optical Doppler tomography (FDODT) system was developed. The technique is based on a phase-resolved method where phase information was retrieved from the reconstructed complex fringe signals. The aliasing effects and artifacts caused by lateral scanning and sample movement were removed with a signal processing technique. The standard deviation of the phase shift of the system was reduced from 49 to 1.8 degrees with the signal processing method employed. Structural, Doppler and Doppler variance images of fluid flow through glass channels were quantified, and blood flow through vessels of chick chorioallantoic membrane (CAM) was demonstrated in vivo.. ©2005 Optical Society of America. Full Article , PDF Article ...
The Orthopedics PERL Channel contains hundreds of items, including full-color medical illustrations, medical animations and patient education articles. The Orthopedics Channel covers topics relevant to skeletal and muscular anatomy, orthopedic injury and repair, and general sports medicine. Health Animation channels are produced by Nucleus Medical Media, Inc.
Pregnancy hcg levels while breastfeeding - Reasons of high hCG levels other than pregnancy? See below. In addition to normal pregnancy, HCG is elevated in ectopic pregnancy, molar pregnancy, retained products of conception, around menopause, and tumors of chorionic tissue. See this site for more information. Http://www. Webmd. Com/baby/human-chorionic-gonadotropin-hcg.
The long‐term survival and successful integration of implants for tissue replacement and regeneration highly depends upon the fast ingrowth of blood vessels from the surrounding tissues
The hypothesis of an intrinsic defect of germ plasma put forward by Streeter to explain the abnormalities observed in amniotic bands sequence (ABS) was not supported by Torpin, who suggested that the bands derived from early amnion rupture, with formation of mesodermal strings and naked chorion, which then constricted or adhered to fetal parts. Recently, several authors have recorded and discussed possible mechanisms for non-band related malformations in patients with otherwise typical limb constrictions and amputations. The mouse mutant disorganisation (Ds) is a semidominant with 72% of heterozygotes manifesting abnormalities, which include cranioschisis, limb duplications and deficiencies, gastro/thoracoschisis, and papillae protruding from other parts of the body. We report similar abnormalities including papillae in five fetuses and one newborn with ABS and, based on these observations and published reports, we suggest that a human homologue for Ds may be the cause of at least some ...
In the present study, a detailed temporal and spatial placental expression map was generated for all murine PRL/PL family members from E7.5 to E18.5 of gestation in three genetic strains. This detailed analysis uncovered several new markers for some trophoblast cell types that will be useful for future analysis of placental structure in mutant mice with placental phenotypes. Moreover, several important conclusions about regulation of the locus are apparent. First, no two family members have the same expression pattern even when complete temporal and spatial data are examined. Second, most genes are expressed in multiple trophoblast cell subtypes though none were detected in the chorion, where trophoblast stem cells reside, or in syncytiotrophoblast of the labyrinth layer. Third, bioinformatic comparisons of upstream regulatory regions identified predicted transcription factor binding site modules that are shared by genes expressed in the same trophoblast subtype. Fourth, further diversification ...
In these animals the developing embryo shows small allantois. It will never come in contact with chorion. Their yolk sac was large. It comes in contact with chorin. This part will gain blood vessels. This part will come in contact with endometrium of uterus. This is only a contact, but not fusion. Through this contact the embryo will absorb nourishment from mother. This is called chorio vitelline placenta or Yolk sac placenta ...
Intaramniotic infection or chorioamnionitis stands for acute infection of chorion and amnion, most frequently caused by ascedent polymicrob bacterial infection. Presence of symptoms such as fever, abdominal pain, abnormal vaginal bleeding, presence of maternal and fetal tachycardia, and maternal laboratory blood tests showing increased inflammatory parameters all together indicate to this condition. Definite affirmation of this dyagnosis is determinated by amniotic fluid and cervical smear microorganism cultivation, and patohystologic changes in fetal membrain and placenta. Due to a wide spectrum of appearing symptoms and a variety of clinical signs and symptoms that are not always immidiately recognised as intraamniac infection, and despite the antibiotic treatment, choriamnionitis often ends in premature birth. The child is more affected by the complications of this condition than the mother. The extent and severity of complications is increasing as the gestation week is smaller and the lower ...
With the exception of birds, most non-mammalian vertebrates depend on the production of a relatively large number of eggs with only a small proportion surviving. Mammals have evolved a system wherein relatively few eggs are produced, but the survival rate is relatively high. This is accomplished by a combination (in all except the prototheres) of prenatal care and, in most, post-natal care.. In the generalized early development in eutherian mammals, the early cleavages produce the blastocyst, a hollow ball of cells. A cluster of cells intrude into the cavity of the blastocyst: the inner cell mass. This eventually will produce the embryo and some extraembryonic membranes. The outer layer of the blastocyst is the trophoblast. The trophoblast eventually develops into the chorion of the placenta and associated structures.. The placenta forms the connection between mother and child, allowing for nutrition, gases, and excretionary materials to move by diffusion between embryonic and maternal ...
variation. Drosophila. Egg chamber. Eggshell (chorion). ?. ?. Y*. The experimental system. Cellular responses. EGFR/ErbB Signaling Network. Invertebrates. Vertebrates. ErbB3. EGFR. ErbB2. EGFR. signal diversification • inhibitors ?. signal diversification: • heterodimerization. Slideshow 5135164 by fadhila
In medical terminology En Caul Baby Birth is a rare term. It connotes a situation where the baby finds itself in an amniotic sac and this is right after birth. This sac is full of fluid inside the womb where the baby grows and develops. It is also known as membranes as the sac is embedded with a couple of them known as the chorion and amnion. The sac is filled with a plain fluid liquid where the baby moves and floats. This sac tends to break on its own after birth and as per the mother it is known as water breaking. It has to be stated that in this form of birth the baby is born inside the intact membranes.. In certain cases the baby is born with a caul attached to their head or face. Babies who are born in this manner are stated to be the ones born with a shirt. It is harmless and the piece of membrane is being removed by the doctor in an easy manner. Sometimes this form of birth is considered to be frightening for a mother but just consider it as a harmless form of birth.. This form of birth ...
Nasonia presents a number of technical challenges that make the work of Li et al. notable. Nasonia female lay eggs in the pupae of other insects. In the laboratory Sarchophaga bullata is a common host whose pupae are commercially available and can be stored in cool temperatures for prolonged periods. When needed the pupae are presented to gravid females in a way the results in Nasonia eggs only being laid at one end of the pupae. To access the freshly laid eggs the pupal cuticle at the end containing the eggs is removed, exposing a cluster of eggs.. The eggs have a very thin, transparent chorion and while small, the eggs are readily injected using technologies and procedures available for the injection of other insect embryos.. The injected eggs are then placed back into a pupa and allowed to develop and emerge. Li et al (2017) have successfully solved these various technical challenges and have successfully created mutations using Cas9.. ...
Electroporation affects the transfer of fluorescein through inner membranes, but not the chorion. Embryos were incubated with 10 μg/ml fluorescein for 40 minut
Timothy as Clive Trevelyan in the Miss Marple Mystery titled The Sittaford Mystery. Picture above © Copyright Jeremy Clulow.. In January 2006, Timothy was busy filming his role as Clive Trevelyan in the Miss Marple Mystery titled The Sittaford Mystery, which was Episode 8. This is a television movie. In this project Timothys character of Clive Trevelyan is the owner of a mansion on the moors, which is a guest house where Miss Marple goes to stay. Clive Trevelyan is also an eminent politician tipped to be the next Prime Minister. This Miss Marple Mystery was co-produced by Granada and Agatha Christie Ltd (A Chorion Company) and WGBH in Boston USA and aired on ITV1 in the UK in the Spring of 2006 and will air in the States on July 23rd 2006 on PBS.. In 2007 Timothy narrated a couple of animated films by a young Russian producer/director about Beethoven and Vivaldi both of these films are aimed at Children. Timothy also narrated a Audio Book called Christine Falls by author Benjamin Black which ...
Synonyms for amnions in Free Thesaurus. Antonyms for amnions. 2 synonyms for amnion: amnios, amniotic sac. What are synonyms for amnions?
This months topic covers pregnancy. today we look at how the body changes as baby grows in mums tum. frequent trips to the loo as the uterus presses on the bladder as baby grows inside. a glowing complection yet at first skin may be blotchy as the hormones kick in . Stretch marks and there is no cream that can make …Continue reading →. ...
TY - JOUR. T1 - Retinoic acid-induced glandular metaplasia in mouse skin is linked to the dermal expression of retinoic acid receptor β mRNA. AU - Viallet, Jean P.. AU - Ruberte, Esther. AU - du Manoir, Stanislas. AU - Krust, Andrée. AU - Zelent, Arthur. AU - Dhouailly, Danielle. PY - 1991/4. Y1 - 1991/4. N2 - The distribution of transcripts of nuclear (RARα, RARβ, and RARγ) and cytosolic (CRABP) retinoic acid receptors was analyzed in 13.5-day mouse embryo upper-lip skin, cultured in vitro for 48 hr with or without added retinoic acid. The results show a significant up-regulation of the transcription of the RARβ gene concomitant with the initiation of an alteration of hair vibrissae follicle development, leading, after transfer for 8 days to the chick embryo chorioallantoic membrane, to an exocrine-type gland morphogenesis.. AB - The distribution of transcripts of nuclear (RARα, RARβ, and RARγ) and cytosolic (CRABP) retinoic acid receptors was analyzed in 13.5-day mouse embryo ...
Definition of chorioallantoic placenta. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
TY - JOUR. T1 - Hydrogen sulphide induces angiogenesis. AU - Pyriochou, Anastasia. AU - Marazioti, Antonia. AU - Szabo, Csaba. AU - Papapetropoulos, Andreas. PY - 2009. Y1 - 2009. N2 - Hydrogen sulphide (H2S) is emerging as an important signalling molecule in the cardiovascular and neuronal systems. Although H2S is known to relax vascular smooth muscle leading to a reduction in blood pressure, the role of this gaseous mediator in other aspects of the biology of vascular cells remains largely unexplored. In order to study the effects of H2S on neovascularisation, we have utilised an aqueous formulation of H2S. Incubation of endothelial cells (EC) with H2S enhanced their angiogenic potential as it promoted cell growth, migration and capillary morphogenesis on matrigel. In line with the in vitro observations, treatment of chicken chorioallantoic membranes (CAM) with H2S increased vascular length. Morever, exposure of EC to H2S resulted in increased phosphorylation of kinases linked to angiogenic ...
Scientists at Childrens Hospital Oakland Research Institute (CHORI) led by Vladimir Serikov, MD, PhD, and Frans Kuypers, PhD, report in the current Epub issue of Stem Cells Translational Medicine that placental stem cells with important therapeutic properties can be harvested in large quantities from the fetal side of human term placentas (called the chorion). The chorion is a part of the afterbirth and is normally discarded after delivery, but it contains stem cells of fetal origin that appear to be pluripotent -- i.e., they can differentiate into different types of human cells, such as lung, liver, or brain cells. Since these functional placental stem cells can be isolated from either fresh or frozen term human placentas, this implies that if each individuals placenta is stored at birth instead of thrown away, these cells can be harvested in the future if therapeutic need arises. This potential represents a major breakthrough in the stem cell field.
Reptiles generally reproduce sexually, though some are capable of asexual reproduction. All reproductive activity occurs through the cloaca, the single exit/entrance at the base of the tail where waste is also eliminated. Most reptiles have copulatory organs, which are usually retracted or inverted and stored inside the body. In turtles and crocodilians, the male has a single median penis, while squamates, including snakes and lizards, possess a pair of hemipenes, only one of which is typically used in each session. Tuatara, however, lack copulatory organs, and so the male and female simply press their cloacas together as the male discharges sperm.[106]. Most reptiles lay amniotic eggs covered with leathery or calcareous shells. An amnion, chorion, and allantois are present during embryonic life. The eggshell (1) protects the crocodile embryo (11) and keeps it from drying out, but it is flexible to allow gas exchange. The chorion (6) aids in gas exchange between the inside and outside of the ...
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We found that Turners syndrome in Denmark was diagnosed prenatally at a rate that was much higher than the observed postnatal rate. The result was highly significant for both amniocentesis and chorion villus sampling, and when cases referred after ultrasonography were excluded. The rate of spontaneous abortion in the first trimester is estimated to be 99%, but this high rate of abortion can only partially explain our findings.2 12 The fact that 91% of all fetuses with the syndrome detected by amniocentesis (and 40% of those detected by chorion villus sampling) survived until term when the pregnancy was not terminated suggests that other factors may play a role and that most fetuses with Turners syndrome detected by amniocentesis are viable.. Hook and Warburton presented data from the New York State Chromosome Registry, where, for every 100000 female fetuses tested by amniocentesis, about 85 (95% confidence interval 54 to 127) cases of Turners syndrome were detected. We found 176 (134 to 215) ...
Question - Pregnant. Ultra sound scan showed monochorionic twins. Meaning? . Ask a Doctor about Gestational sac, Ask an OBGYN, Gynecologic Oncology
Explaination: Explanation: Placenta and chorion compose the fetal-maternal junction. The former is a trophoblast derivative and the latter is a derivative of both trophoblast and extraembryonic mesoderm. The other extraembryonic tissues such as the amnion, the yolk sac and the allantois are derived from the inner cell mass. Among them, the yolk sac and the allantois are endodermal derivatives whereas the amnion is an ectodermal derivative ...
The placenta is an ephemeral (temporary) organ present only in female marsupial and placental mammals during gestation (pregnancy). The placenta is composed of two parts, one of which, the chorion, is genetically and biologically part of the fetus, the other part of the mother. It is implanted in the wall of the uterus, where it receives nutrients from the mothers blood and passes out waste. This interface forms a barrier, the placental barrier, which filters out many substances which could harm the fetus. However, many other substances are not filtered out, including alcohol. Most viruses also easily cross this barrier. The placenta is connected to the fetus via the umbilical cord which is composed of blood vessels and connective tissue. When the fetus is delivered, the placenta is delivered afterwards (and for this reason is often called the afterbirth). After delivery of the placenta the umbilical cord is usually clamped and severed or may be left attached to fall off naturally which is ...
Read story Abnormalities of Fetal Membranes and Amniotic Fluid by cgbeamd with 2,934 reads.ABNORMALITIES OF FETAL MEMBRANES AND AMNIOTIC FLUID Abnormalities o...
Following successful premieres on Cartoon Network in the U.S. and Five in the U.K, Chorions new animated series The Mr. Men Show is set to make its French debut on France 5 on ... Continue Reading → ...
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A new review looks at the potential of fetal membranes, which make up the amniotic sac surrounding the fetus during pregnancy, for regenerative medicine.
Angiogenesis is closely related to the growth, invasion and metastasis of tumors, also considered as the key target of anticancer therapy. Scutellaria barbata D. Don (S. barbata), a traditional Chinese medicine, is being used to treat various diseases, including cancer. However, the antitumor molecular mechanism of S. barbata was still unclear. This study aimed to investigate the inhibitory effects of the total flavones in S. barbata (TF-SB) on angiogenesis. Human umbilical vein endothelial cells (HUVECs) were treated with various concentrations of TF-SB. Cell viability was examined using the MTT assay. The scratch assay was used to detect the migration of HUVECs after treatment with TF-SB. The ability of HUVECs to form network structures in vitro was demonstrated using the tube formation assay. The chick embryo chorioallantoic membrane assay was performed to detect the in vivo anti-angiogenic effect. The expression of VEGF was measured by the enzyme-linked immunosorbent. Results showed that TF-SB
Figure 6: |i|Viola tricolor|/i| Induces Apoptosis in Cancer Cells and Exhibits Antiangiogenic Activity on Chicken Chorioallantoic Membrane
Here, we address the morphological changes of eyed eggs of Atlantic salmon, Salmo salar L. infected with Saprolegnia from a commercial hatchery and after experimental infection. Eyed eggs infected with Saprolegnia spp. from 10 Atlantic salmon females were obtained. Egg pathology was investigated by light and scanning electron microscopy. Eggs from six of ten females were infected with S. parasitica, and two females had infections with S. diclina clade IIIA; two Saprolegnia isolates remained unidentified. Light microscopy showed S. diclina infection resulted in the chorion in some areas being completely destroyed, whereas eggs infected with S. parasitica had an apparently intact chorion with hyphae growing within or beneath the chorion. The same contrasting pathology was found in experimentally infected eggs. Scanning electron microscopy revealed that S. parasitica grew on the egg surface and hyphae were found penetrating the chorion of the egg, and re-emerging on the surface away from the ...
Rigorous and systematic pre-clinical studies are necessary and essential to establish the efficacy and safety of Oriental herbs and formulas in order to transform traditional herbal practices into evidence-based medicine. Here we evaluated the anti-cancer activities of the ethanol extract of Ka-mi-kae-kyuk-tang (KMKKT), a formula of ten Oriental herbs, with a battery of in vitro and in vivo mechanism-based biomarkers involving angiogenesis, apoptosis and metastasis. The results show that KMKKT suppressed the vascular endothelial responses by inhibiting basic fibroblast growth factor (bFGF)-induced ERK1/2 phosphorylation, cell migration as well as tube formation in the human umbilical vein endothelial cell model, and decreased the hypoxia-induced HIF1α and vascular epithelial growth factor (VEGF) expression in the mouse Lewis lung carcinoma (LLC) cells in vitro, and inhibited the bFGF-induced angiogenesis in chick chorioallantoic membrane model, and in the Matrigel plugs in mice. Intraperitoneal ...
In chick chorioallantoic membrane (CAM) assays, injection of cilengitide into CAM vasculature prevented the growth of implanted U87MG glioma and DAOY medulloblastoma tumor fragments compared to the inactive peptide EMD135981. The inhibition of tumor growth was attributed to the anti-angiogenic activity of cilengitide as membrane vascularity surrounding the tumor graft was greatly decreased by cilengitide treatment as compared to the inactive control peptide [130]. In animal models, cilengitide, as a single agent effectively inhibited the growth and proliferation of orthotopically implanted malignant glioma and medulloblastoma cell lines in nude mice. Daily treatment of established xenografts with 100-200 µg cilengitide significantly delayed tumor growth and prolonged survival compared to controls. The delayed tumor growth was accompanied by increases in CD31 and tumor doubling times, elevated apoptotic index and decreases in proliferative index and tumor vessel number and density [130]. ...
A monoclonal antibody GB25 which was raised against placental syncytiotrophoblast reacted specifically with villous trophoblasts. It recognized syncytiotrophoblast, villous cytotrophoblasts of the first-trimester placentae, and a majority of the cytotrophoblasts in the chorion laeve, but not the residual cells of cytotrophoblastic shell in the basal plates and the cells in the cytotrophoblastic columns. This antibody will be useful for isolating and differentiating villous from extravillous cytotrophoblasts in the first-trimester placentae.
Multifetal gestations are classified on the basis of zygosity and chorionicity.1Dizygotic twins arise from independent fertilization of separate ova. Typically, two placentas form with distinct chorionic and amniotic membranes separating each fetus. Monozygotic twins develop from a single fertilized ovum that subsequently divides at or before the blastocyst stage of embryogenesis. The factors promoting fission of the conceptus are poorly understood. The timing of embryonic division determines whether the monozygotic twins will be separated by amnion and chorion (dichorionic, diamniotic), amnion only (monochorionic, diamniotic), or not separated (monoamniotic, monochorionic). Dizygotic twins account for about two thirds of spontaneous twin births and are almost always dichorionic, diamniotic. Monochorionic twins share a single placenta with a shared circulation. This developmental phenomenon carries a significant mortality risk and may lead to complications such as twin-twin transfusion syndrome ...
The risk of perinatal morbidity and mortality in twins is 3-7 times higher than in singletons. In comparison to dichorionic twins, monochorionic twins are at increased risk for perinatal mortality and serious morbidity. In both type of twins growth discordance can occur. Discordant growth of dichorionic twins could be due to differences in placental mass or differences in placental parenchymal lesions, whereas birth weight discordancy in monochorionic twins is caused by placental vascular anastomoses. In this review the different types of complications (acardiac twins, acute and chronic twin-twin transfusion syndrome) due to different combinations of vascular anastomoses are discussed in relation to a computer model developed to gain more insight into the development of the twin-twin transfusion syndrome. The angioarchitecture of 395 monochorionic twin placentas was studied. Mortality was highest in the absence of an arterio-arterial anastomosis (42%) and lowest in the presence of an ...
Glaucium flavum (G. flavum) is a plant from the Papaveraceae family native to Algeria where it is used in local traditional medicine to treat warts. G. flavum root crude alkaloid extract inhibited breast cancer cell proliferation and induced G2/M phase cycle arrest and apoptosis without affecting normal cells, which is a highly awaited feature of potential anti-cancer agents. G. flavum significantly reduced growth and vascularization of human glioma tumors on chicken chorioallantoic membrane (CAM) in vivo. The chromatographic profile of the dichloromethane extract of G. flavum root showed the presence of different constituents including the isoquinoline alkaloid protopine, as the major compound. We report for the first time that G. flavum extract may represent a new promising agent for cancer chemotherapy.
Following widespread application of assisted reproductive technology modalities and the increased age of motherhood, the incidence of twin gestations has increased markedly. Twins are either monozygotic or dizygotic. Dizygotic (i.e. fraternal) twins result from the fertilization of two different eggs and are per definition dichorionic (DC). Chorionicity of monozygotic twins ... read more (i.e. identical twins) depends on timing of splitting of the fertilized egg. If splitting occurs within three days after fertilization, the monozygotic twin will be DC. Splitting after the third day results in monochorionic (MC) twinning. Twins have an increased risk of perinatal mortality and neonatal morbidity compared to singletons. MC twin pregnancies, which occur in about 1 of 400 pregnancies, carry a higher risk of perinatal complications compared to DC twins. This is mainly attributed to the unique architecture of the MC placenta. The aim of this thesis was to study perinatal mortality and (long-term) ...
... eggs are protected by a hard-ridged outer layer of shell, called the chorion. This is lined with a thin coating of ...
chorion / amnion *Amniotic band syndrome. *Chorioamnionitis. *Chorionic hematoma. *Monoamniotic twins. *Premature rupture of ...
chorion / amnion *Amniotic band syndrome. *Chorioamnionitis. *Chorionic hematoma. *Monoamniotic twins. *Premature rupture of ...
The chorion (6) aids in gas exchange between the inside and outside of the egg. It allows carbon dioxide to exit the egg and ... An amnion, chorion, and allantois are present during embryonic life. The eggshell (1) protects the crocodile embryo (11) and ... 1. eggshell, 2. yolk sac, 3. yolk (nutrients), 4. vessels, 5. amnion, 6. chorion, 7. air space, 8. allantois, 9. albumin (egg ...
While in extreme conditions, such as low oxygen level or salinity above 150‰, female brine shrimp produce eggs with a chorion ...
... they form the ectoderm of the chorion and play an important part in the development of the placenta. On the deep surface of the ...
Primary polycythemias are due to factors intrinsic to red cell precursors. Polycythemia vera (PCV), polycythemia rubra vera (PRV), or erythremia, occurs when excess red blood cells are produced as a result of an abnormality of the bone marrow.[3] Often, excess white blood cells and platelets are also produced. PCV is classified as a myeloproliferative disease. Symptoms include headaches and vertigo, and signs on physical examination include an abnormally enlarged spleen and/or liver. In some cases, affected individuals may have associated conditions including high blood pressure or formation of blood clots. Transformation to acute leukemia is rare. Phlebotomy is the mainstay of treatment. A hallmark of polycythemia is an elevated hematocrit, with Hct , 55% seen in 83% of cases.[4] A somatic (non-hereditary) mutation (V617F) in the JAK2 gene is found in 95% of cases, though also present in other myeloproliferative disorders.[5] Primary familial polycythemia, also known as primary familial and ...
Chorion. *Dural sac, a structure of spinal cord. *Egg sac, the reproductive structure of a spider ...
... such as the placenta in mammals and the chorion in birds. ...
Hos morkakedyr er chorion en viktig faktor i dannelsen av morkaken. Hos mange parasitter, særlig rundormer, har eggene en ... Hos virveldyr kalles den ytre hinnen chorion. Hos mange dyr med ytre befruktning gjennomgår egget en forandring etter ...
During childbirth, the detachment of the placental chorion can cause excessive bleeding.[42] ... in which the chorion erodes the uterine epithelium and has direct contact with maternal blood. The other placental phenotypes ...
chorion / amnion *Amniotic band syndrome. *Chorioamnionitis. *Chorionic hematoma. *Monoamniotic twins. *Premature rupture of ...
Multiples may become monochorionic, sharing the same chorion, with resultant risk of twin-to-twin transfusion syndrome. ...
chorion / amnion *Amniotic band syndrome. *Chorioamnionitis. *Chorionic hematoma. *Monoamniotic twins. *Premature rupture of ...
Multiples may be monochorionic, sharing the same chorion, with resultant risk of twin-to-twin transfusion syndrome. ...
Normally, twins have two separate (di- being a numerical prefix for two) chorions and amniotic sacs, termed Dichorionic- ...
It can be induced to assist thoracoscopic surgery.[7] It can be caused by a pulmonary barotrauma resulting when a person moves to or from a higher pressure environment, such as when a SCUBA diver,[8][9] a free-diver[10] or an airplane passenger[11] ascends or descends. In rare cases, pneumomediastinum may also arise as a result of blunt chest trauma (e.g. car accidents, fights, over pressure of breathing apparatus), while still evolving in the same fashion as the spontaneous form.[12] Pneumomediastinum is most commonly seen in otherwise healthy young male patients and may not be prefaced by a relevant medical history of similar ailments.[13] ...
Drosophila melanogaster, a fruit fly, is a model organism in biology on which much research into embryology has been done.[2] Before fertilization, the female gamete produces an abundance of mRNA - transcribed from the genes that encode bicoid protein and nanos protein.[3][4] These mRNA molecules are stored to be used later in what will become the developing embryo. The male and female Drosophila gametes exhibit anisogamy (differences in morphology and sub-cellular biochemistry). The female gamete is larger than the male gamete because it harbors more cytoplasm and, within the cytoplasm, the female gamete contains an abundance of the mRNA previously mentioned.[5][6] At fertilization, the male and female gametes fuse (plasmogamy) and then the nucleus of the male gamete fuses with the nucleus of the female gamete (karyogamy). Note that before the gametes' nuclei fuse, they are known as pronuclei.[7] A series of nuclear divisions will occur without cytokinesis (division of the cell) in the zygote ...
chorion / amnion *Amniotic band syndrome. *Chorioamnionitis. *Chorionic hematoma. *Monoamniotic twins. *Premature rupture of ...
chorion / amnion *Amniotic band syndrome. *Chorioamnionitis. *Chorionic hematoma. *Monoamniotic twins. *Premature rupture of ...
Diagram of a fish egg: A. vitelline membrane B. chorion C. yolk D. oil globule E. perivitelline space F. embryo ...
... with a crescent-like chorion.[47] ...
The ova develop into eggs that have a covering called the chorion, which forms before internal fertilization. Insects have very ...
... where the maternal blood does not come in direct contact with the fetal chorion like it does in the hemochorial placenta of ...
Prevention includes the use of breast milk and probiotics.[2] A 2012 policy by the American Academy of Pediatrics recommended feeding preterm infants human milk, finding "significant short- and long-term beneficial effects," including reducing the rate of NEC by a factor of two or more.[10] Small amounts of oral feeds of human milk starting as soon as possible, while the infant is being primarily fed intravenously, primes the immature gut to mature and become ready to receive greater intake by mouth.[11] Human milk from a milk bank or donor can be used if mother's milk is unavailable. The gut mucosal cells do not get enough nourishment from arterial blood supply to stay healthy, especially in very premature infants, where the blood supply is limited due to immature development of the capillaries, so nutrients from the lumen of the gut are needed. A Cochrane review in 2014 found that supplementation of probiotics enterally "prevents severe NEC as well as all-cause mortality in preterm ...
The paralysis can be partial or complete; the damage to each nerve can range from bruising to tearing. The most commonly involved root is C5 (aka Erb's point: the union of C5 & C6 roots)[6] as this is mechanically the furthest point from the force of traction, therefore, the first/most affected.[7] Erb-Duchenne palsy presents as a lower motor neuron syndrome associated with sensibility disturbance and vegetative phenomena.[8] The most commonly involved nerves are the suprascapular nerve, musculocutaneous nerve, and the axillary nerve.[9][10] The signs of Erb's palsy include loss of sensation in the arm and paralysis and atrophy of the deltoid, biceps, and brachialis muscles.[6] "The position of the limb, under such conditions, is characteristic: the arm hangs by the side and is rotated medially; the forearm is extended and pronated. The arm cannot be raised from the side; all power of flexion of the elbow is lost, as is also supination of the forearm".[7] The resulting biceps damage is the main ...
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The Fetal Medicine Foundation is a Registered Charity that aims to improve the health of pregnant women and their babies through research and training in fetal medicine.
They are integral to increasing the surface area of the uterus, forming the chorion (which in turn produces the placenta) and ...
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Chorion protein 3 Gene controlling chorion proteins.Spontaneous; smaller Chorion gene cluster consisting largely of early genes ... Chorion protein 1・2 Gene controlling chorion proteins.Spontaneous; multigene family comprising one large gene cluster that ...
The Effect of the Chorion on Size-Dependent Acute Toxicity and Underlying Mechanisms of Amine-Modified Silver Nanoparticles in ...
Characterization of group B streptococcal invasion of human chorion and amnion epithelial cells In vitro. Infect Immun. 1998 ...
The AP stress view of the ankle is a highly specialized view used to assess the integrity of the syndesmosis and deltoid ligament. It can be performed one of two ways, with gravity or via manual external rotation. Indications In intermediate a...
Placenta Chorion , Amnion and Proamnion , The Yolk Sack, Allantois and Umbilical Cord , Placenta Gastrointestinal Tract ... Chorion , Amnion and Proamnion , The Yolk Sack, Allantois and Umbilical Cord , Placenta , The Foetus , Growth and External ...
Here we report new ECM like biomaterials, pFZC, obtained from the fertilized Zebrafish chorion (FZC). ...
Sinds het bestaan van de ultrasonografie en meer ingrijpende technieken zoals de vlokkentest ("chorion villus sampling") en de ... The introduction of ultrasonography and more invasive procedures, such as chorion villus sampling and amniocentesis, allow to ...
The human placenta is comprised of the inner amniotic membrane and the outer chorion.14 At an ultrastructural level, amniotic ... Zelen et al8 compared a cultured tissue (Apligraf, Organogenesis Inc, Canton, MA), to a dehydrated human amnion/chorion (EpiFix ... A prospective, randomised comparative study of weekly versus biweekly application of dehydrated human amnion/chorion membrane ... a significantly higher rate of closure as well as a shortened time to closure using the dehydrated human amnion/chorion. Lavery ...
... in cultured human fetal membrane chorion cells. ...
The superiority of fish-skin xenografts over dehydrated human amnion/chorion allografts has been established in a randomised ... The superiority of fish-skin xenografts over dehydrated human amnion/chorion allografts (dHACM) for the treatment of acute ...
The chorions job is to establish a connection between the life-sustaining womb and the embryo, tapping into blood vessels in ... At this stage, the embryo casts a membrane around itself called the chorion, which is the inner layer of the developing ... Once this critical link is made, the placenta will begin to form around the chorion and embryo, the intermediary zone between ... We now understand that the "Chorion" in Human Chorionic Gonadotropin is related to the formation of the placenta. hCG is now ...
Chorion. Chorion (Uniprot/TrEMBL) Colon Cecum. Colon. Connective Tissue Layers of Skin. Connective Tissue. Coronary Artery. ... Chorion. Epithelial Cells. Embryonic Fibroblasts. Middle First Trimester. Late First Trimester. Second Trimester. Left Atrium. ...
... with multilayer devitalized dehydrated human amnion/chorion membrane (dHACM) in wound-relevant models to determine the effect ...
A horseshoe adrenal gland is a very rare anomaly. It is also sometimes referred to as a butterfly, fused or midline adrenal gland. It is a solitary adrenal gland that is present in the midline of the fused portion either passing between the aort...
Chorions were removed by gently swirling the embryos in several changes of aquarium water, which also served to remove the ... denuded of their chorions, in SU5402, a widely used inhibitor of Fgf receptor (Fgfr) activation. Predictions based upon ...
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Results of the ultrasound and morphological examination of the villous chorion of women with physiological pregnancy (34 cases ...
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About 7 to 9 follicles in each ovariole are loaded progressively with vitellus and secrete a chorion. However, enriched T-cells ...
... that myxoma of the chorion is usually caused by endometritis which has existed prior to conception. A congested conjunctiva, a ...
... yolk sac and chorion). Just prior to hatching, the chick pokes its beak through the membranes (pips) into the air cell and ...
  • Methods: Ten healthy adult patients presenting with 21 Miller Class I gingival recession (GR) defects (isolated or adjacent multiple) were surgically treated with a modified coronally advanced flap and chorion membrane for root coverage. (elsevier.com)
  • The chorion membrane covered by a modified coronally advanced flap is a new approach that has shown promising results in terms of root coverage, increased width of keratinized tissue, and thickness of the gingival biotype. (elsevier.com)
  • moreover, the spacing of ribosomes on chorion mRNA (30-37 codons per ribosome) is similar to that encountered in other eukaryotic systems. (rupress.org)
  • Silkmoth follicles, arranged in a precise developmental sequence within the ovariole, yield pure and uniform populations of follicular epithelial cells highly differentiated for synthesis of the proteinaceous eggshell (chorion). (rupress.org)
  • For 2 days the cells are devoted almost exclusively to production of distinctive chorion proteins of low molecular weight and of unusual amino acid composition. (rupress.org)
  • Electron microscopic studies on the development of the chorion of the viviparous teleost Dermogenys pusillus (Hemirhamphidae). (pianolarge.ml)