Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
A febrile disease occurring as a delayed sequela of infections with STREPTOCOCCUS PYOGENES. It is characterized by multiple focal inflammatory lesions of the connective tissue structures, such as the heart, blood vessels, and joints (POLYARTHRITIS) and brain, and by the presence of ASCHOFF BODIES in the myocardium and skin.
A rare movement disorder developed during PREGNANCY, characterized by involuntary jerky motion (CHOREA) and inability to maintain stable position of body parts (ATHETOSIS). RHEUMATIC FEVER and collagen vascular disorders are frequently associated with this disease. Chorea may vary from mild to severe and occurs in approximately 1 per 2,000 to 3,000 pregnancies. (From Md Med J 1997 Sep;46(8):436-9)
Drugs used in the treatment of movement disorders. Most of these act centrally on dopaminergic or cholinergic systems. Among the most important clinically are those used for the treatment of Parkinson disease (ANTIPARKINSON AGENTS) and those for the tardive dyskinesias.
Disorders caused by cellular or humoral immune responses primarily directed towards nervous system autoantigens. The immune response may be directed towards specific tissue components (e.g., myelin) and may be limited to the central nervous system (e.g., MULTIPLE SCLEROSIS) or the peripheral nervous system (e.g., GUILLAIN-BARRE SYNDROME).
A serious complication of TYPE 2 DIABETES MELLITUS. It is characterized by extreme HYPERGLYCEMIA; DEHYDRATION; serum hyperosmolarity; and depressed consciousness leading to COMA in the absence of KETOSIS and ACIDOSIS.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Intractable VOMITING that develops in early PREGNANCY and persists. This can lead to DEHYDRATION and WEIGHT LOSS.
Infections with bacteria of the genus STREPTOCOCCUS.

Familial essential ("benign") chorea. (1/216)

A family is described with essential non-progressive chorea occurring in an autosomal dominant inheritance pattern over four generations. A few families with an apparently similar disorder have been reported previously. This condition is characterized by early childhood onset of chorea which is not progressive and is compatible with a long life. It is not associated with dementia, seizures, rigidity, or ataxia. It is a socially embarrassing condition and may, sometimes, be associated with behavioural problems and learning difficulties. For genetic counselling, it is important to distinguish this disorder from Huntington's disease and other hereditary disorders associated with chorea.  (+info)

Rheumatic chorea in northern Australia: a clinical and epidemiological study. (2/216)

To describe the epidemiology and clinical features of Sydenham's chorea in the Aboriginal population of northern Australia a review was conducted of 158 episodes in 108 people: 106 were Aborigines, 79 were female, and the mean age was 10.9 years at first episode. Chorea occurred in 28% of cases of acute rheumatic fever, carditis occurred in 25% of episodes of chorea, and arthritis in 8%. Patients with carditis or arthritis tended to have raised acute phase reactants and streptococcal serology. Two episodes lasted at least 30 months. Mean time to first recurrence of chorea was 2.1 years compared with 1.2 years to second recurrence. Established rheumatic heart disease developed in 58% of cases and was more likely in those presenting with acute carditis, although most people who developed rheumatic heart disease did not have evidence of acute carditis with chorea. Differences in the patterns of chorea and other manifestations of acute rheumatic fever in different populations may hold clues to its pathogenesis. Long term adherence to secondary prophylaxis is crucial following all episodes of acute rheumatic fever, including chorea, to prevent recurrence.  (+info)

Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics. (3/216)

Anticonvulsants cause dyskinesias more commonly than has been appreciated. Diphenylhydantoin (DPH), carbamazepine, primidone, and phenobarbitone may cause asterixis. DPH, but not other anticonvulsants, may cause orofacial dyskinesias, limb chorea, and dystonia in intoxicated patients. These dyskinesias are similar to those caused by neuroleptic drugs and may be related to dopamine antagonistic properties possessed by DPH.  (+info)

Paroxysmal kinesigenic choreoathetosis associated with frontotemporal arachnoid cyst--case report. (4/216)

A 17-year-old male presented with paroxysmal kinesigenic choreoathetosis (PKC) associated with frontotemporal arachnoid cyst. Xenon-133 single photon emission computed tomography detected a slight but equivocal decrease in regional cerebral blood flow in the vicinity of basal ganglia associated with the PKC episodes. PKC continued after surgical removal of the cyst but was well controlled by oral administration of carbamazepine. Whether the pathogenesis of symptomatic PKC was associated with the cortical lesion could not be determined in the present case.  (+info)

Intracortical inhibition of the motor cortex is normal in chorea. (5/216)

Intracortical inhibition of the motor cortex was investigated using a paired pulse magnetic stimulation method in 14 patients with chorea caused by various aetiologies (six patients with Huntington's disease, one with chorea acanthocytosis, a patient with systemic lupus erythematosus with a vascular lesion in the caudate, three with senile chorea and three with chorea of unknown aetiology). The time course and amount of inhibition was the same in the patients as in normal subjects, suggesting that the inhibitory mechanisms of the motor cortex studied with this method are intact in chorea. This is in striking contrast with the abnormal inhibition seen in patients with Parkinson's disease or focal hand dystonia, or those with a lesion in the putamen or globus pallidus. It is concluded that the pathophysiological mechanisms responsible for chorea are different from those producing other involuntary movements.  (+info)

Movement disorders caused by brain tumours. (6/216)

Movement disorders are uncommon presenting features of brain tumours. Early recognition of such lesions is important to arrest further deficit. We treated seven patients with movement disorders secondary to brain tumours over a period of seven years. Only two of these were intrinsic thalamic tumours (astrocytomas) while the rest were extrinsic tumours. The intrinsic tumours were accompanied by hemichorea. Among the extrinsic tumours, there was one pituitary macroadenoma with hemiballismus and four meningiomas with parkinsonism. Symptoms were unilateral in all patients except one with anterior third falcine meningioma who had bilateral rest tremors. There was relief in movement disorders observed after surgery. Imaging by computed tomography or magnetic resonance imaging is mandatory in the evaluation of movement disorders, especially if the presentation is atypical, unilateral and/or accompanied by long tract signs.  (+info)

From off-period dystonia to peak-dose chorea. The clinical spectrum of varying subthalamic nucleus activity. (7/216)

The effect of chronic bilateral high-frequency stimulation of the subthalamic nucleus (STN) on levodopa-induced dyskinaesias was investigated in eight patients with fluctuating Parkinson's disease complicated by functionally disabling off-period dystonia. All of the patients also had severe diphasic and peak-dose chorea, so that it was possible to study the effect of high-frequency stimulation on the different types of levodopa-induced dyskinaesias. Off-period fixed dystonia was reduced by 90% and off-period pain by 66%. After acute levodopa challenge, high-frequency stimulation of the STN reduced diphasic mobile dystonia by 50% and peak-dose choreic dyskinaesias by 30%. The effect of bilateral high-frequency stimulation of the STN on the Unified Parkinson's Disease Rating Scale motor score had the same magnitude as the preoperative effect of levodopa. This allowed the levodopa dose to be reduced by 47%. The combination of reduced medication and continuous high-frequency stimulation of the STN reduced the duration of on-period diphasic and peak-dose dyskinaesias by 52% and the intensity by 68%. Acute high-frequency stimulation of the STN mimics an acute levodopa challenge, concerning both parkinsonism and dyskinaesias, and suppresses off-period dystonia. Increasing the voltage can induce repetitive dystonic dyskinaesias, mimicking diphasic levodopa-induced dyskinaesias. A further increase in voltage leads to a shift from a diphasic-pattern dystonia to a peak-dose pattern choreodystonia. Chronic high-frequency stimulation of the STN also mimics the benefit of levodopa on parkinsonism and improves all kinds of levodopa-induced dyskinaesias to varying degrees. Off-period dystonia, associated with neuronal hyperactivity in the STN is directly affected by stimulation and disappears immediately. The effect of chronic high-frequency stimulation of the STN on diphasic and peak-dose dyskinaesias is more complex and is related directly to the functional inhibition of the STN and indirectly to the replacement of the pulsatile dopaminergic stimulation by continuous functional inhibition of the STN. Chronic high-frequency stimulation of the STN allows a very gradual increase in stimulation parameters with increasing beneficial effect on parkinsonism while reducing the threshold for the elicitation of stimulation-induced dyskinaesias. In parallel with improvement of parkinsonism, the levodopa dose can be gradually decreased. As diphasic dystonic dyskinaesias are improved to a greater degree than peak-dose dyskinaesias, both direct and indirect mechanisms may be involved. Peak-dose choreatic dyskinaesias, associated with little evidence of parkinsonism and thus with low neuronal activity in the STN, are improved, mostly indirectly. Fixed off-period dystonia, mobile diphasic dystonia and peak-dose choreodystonia seem to represent a continuous clinical spectrum reflecting a continuous spectrum of underlying activity patterns of STN neurons.  (+info)

Paroxysmal kinesigenic choreoathetosis locus maps to chromosome 16p11.2-q12.1. (8/216)

Paroxysmal kinesigenic choreoathetosis (PKC), the most frequently described type of paroxysmal dyskinesia, is characterized by recurrent, brief attacks of involuntary movements induced by sudden voluntary movements. Some patients with PKC have a history of infantile afebrile convulsions with a favorable outcome. To localize the PKC locus, we performed genomewide linkage analysis on eight Japanese families with autosomal dominant PKC. Two-point linkage analysis provided a maximum LOD score of 10.27 (recombination fraction [theta] =.00; penetrance [p] =.7) at marker D16S3081, and a maximum multipoint LOD score for a subset of markers was calculated to be 11.51 (p = 0.8) at D16S3080. Haplotype analysis defined the disease locus within a region of approximately 12.4 cM between D16S3093 and D16S416. P1-derived artificial chromosome clones containing loci D16S3093 and D16S416 were mapped, by use of FISH, to 16p11.2 and 16q12.1, respectively. Thus, in the eight families studied, the chromosomal localization of the PKC critical region (PKCR) is 16p11.2-q12.1. The PKCR overlaps with a region responsible for "infantile convulsions and paroxysmal choreoathetosis" (MIM 602066), a recently recognized clinical entity with benign infantile convulsions and nonkinesigenic paroxysmal dyskinesias.  (+info)

Chorea is a medical term that describes an involuntary movement disorder characterized by brief, irregular, and abrupt jerky movements. These movements often occur randomly and can affect any part of the body. Chorea can also cause difficulty with coordination and balance, and can sometimes be accompanied by muscle weakness or rigidity.

The term "chorea" comes from the Greek word "χορεία" (khoréia), which means "dance," reflecting the graceful, dance-like movements that are characteristic of this condition. Chorea can occur as a symptom of various underlying medical conditions, including neurological disorders such as Huntington's disease, Sydenham's chorea, and cerebral palsy, as well as metabolic disorders, infections, and certain medications.

Treatment for chorea depends on the underlying cause of the condition and may include medications to help control the involuntary movements, physical therapy to improve coordination and balance, and lifestyle modifications to reduce the risk of injury from falls or other accidents. In some cases, surgery may be recommended as a last resort for severe or refractory chorea.

Huntington Disease (HD) is a genetic neurodegenerative disorder that affects both cognitive and motor functions. It is characterized by the progressive loss of neurons in various areas of the brain, particularly in the striatum and cortex. The disease is caused by an autosomal dominant mutation in the HTT gene, which codes for the huntingtin protein. The most common mutation is a CAG repeat expansion in this gene, leading to the production of an abnormal form of the huntingtin protein that is toxic to nerve cells.

The symptoms of HD typically appear between the ages of 30 and 50, but they can start earlier or later in life. The early signs of HD may include subtle changes in mood, cognition, and coordination. As the disease progresses, individuals with HD experience uncontrolled movements (chorea), emotional disturbances, cognitive decline, and difficulties with communication and swallowing. Eventually, they become dependent on others for their daily needs and lose their ability to walk, talk, and care for themselves.

There is currently no cure for HD, but medications and therapies can help manage the symptoms of the disease and improve quality of life. Genetic testing is available to confirm the diagnosis and provide information about the risk of passing the disease on to future generations.

Rheumatic fever is a systemic inflammatory disease that may occur following an untreated Group A streptococcal infection, such as strep throat. It primarily affects children between the ages of 5 and 15, but it can occur at any age. The condition is characterized by inflammation in various parts of the body, including the heart (carditis), joints (arthritis), skin (erythema marginatum, subcutaneous nodules), and brain (Sydenham's chorea).

The onset of rheumatic fever usually occurs 2-4 weeks after a streptococcal infection. The exact cause of the immune system's overreaction leading to rheumatic fever is not fully understood, but it involves molecular mimicry between streptococcal antigens and host tissues.

The Jones Criteria are used to diagnose rheumatic fever, which include:

1. Evidence of a preceding streptococcal infection (e.g., positive throat culture or rapid strep test, elevated or rising anti-streptolysin O titer)
2. Carditis (heart inflammation), including new murmurs or changes in existing murmurs, electrocardiogram abnormalities, or evidence of heart failure
3. Polyarthritis (inflammation of multiple joints) – typically large joints like the knees and ankles, migratory, and may be associated with warmth, swelling, and pain
4. Erythema marginatum (a skin rash characterized by pink or red, irregularly shaped macules or rings that blanch in the center and spread outward)
5. Subcutaneous nodules (firm, round, mobile lumps under the skin, usually over bony prominences)
6. Sydenham's chorea (involuntary, rapid, irregular movements, often affecting the face, hands, and feet)

Treatment of rheumatic fever typically involves antibiotics to eliminate any residual streptococcal infection, anti-inflammatory medications like corticosteroids or nonsteroidal anti-inflammatory drugs (NSAIDs) to manage symptoms and prevent long-term heart complications, and secondary prophylaxis with regular antibiotic administration to prevent recurrent streptococcal infections.

Chorea gravidarum is a rare condition characterized by involuntary, irregular, and abrupt movements known as chorea, which typically affect the face, arms, and legs. This condition usually occurs during pregnancy or after childbirth. The exact cause of chorea gravidarum is not well understood, but it is believed to be related to hormonal changes and fluctuations during pregnancy.

Chorea gravidarum can range from mild to severe in its presentation. In some cases, the movements may be barely noticeable, while in others, they can interfere with daily activities and quality of life. The condition may also cause emotional lability, which refers to rapid and unpredictable shifts in mood or behavior.

Chorea gravidarum is typically treated with medications that help to reduce the severity of the movements and improve symptoms. These medications may include anticholinergics, dopamine-blocking agents, or benzodiazepines. In some cases, supportive therapies such as physical therapy or occupational therapy may also be recommended to help manage symptoms and improve function.

It is important to note that chorea gravidarum can pose risks to both the mother and the developing fetus. Women who experience this condition should be closely monitored by their healthcare provider throughout pregnancy and postpartum period to ensure the best possible outcomes for both.

Anti-dyskinetic agents are a class of medications that are used to treat or manage dyskinesias, which are involuntary movements or abnormal muscle contractions. These medications work by blocking or reducing the activity of dopamine, a neurotransmitter in the brain that is involved in movement control.

Dyskinetic symptoms can occur as a side effect of long-term use of levodopa therapy in patients with Parkinson's disease. Anti-dyskinetic agents such as amantadine, anticholinergics, and dopamine agonists may be used to manage these symptoms.

Amantadine works by increasing the release of dopamine and blocking its reuptake, which can help reduce dyskinesias. Anticholinergic medications such as trihexyphenidyl and benztropine work by blocking the action of acetylcholine, another neurotransmitter that can contribute to dyskinesias. Dopamine agonists such as pramipexole and ropinirole mimic the effects of dopamine in the brain and can help reduce dyskinesias by reducing the dose of levodopa required for symptom control.

It is important to note that anti-dyskinetic agents may have side effects, and their use should be carefully monitored by a healthcare provider.

Autoimmune diseases of the nervous system are a group of conditions that occur when the body's immune system mistakenly attacks healthy tissue in the brain, spinal cord, or nerves. These diseases can cause inflammation, damage to nerve cells, and interference with the transmission of nerve impulses, leading to various neurological symptoms.

Examples of autoimmune diseases that affect the nervous system include:

1. Multiple sclerosis (MS): A chronic disease characterized by damage to the protective covering of nerve fibers in the brain and spinal cord, causing a variety of neurological symptoms such as muscle weakness, vision problems, and difficulty with coordination and balance.
2. Myasthenia gravis: A condition that causes muscle weakness and fatigue, particularly affecting the eyes, face, and neck muscles. It occurs when the immune system attacks the receptors that transmit signals between nerves and muscles.
3. Guillain-Barré syndrome: A rare disorder in which the body's immune system attacks the nerves, causing muscle weakness, tingling, and numbness that can spread throughout the body. In severe cases, it can lead to paralysis and respiratory failure.
4. Neuromyelitis optica (NMO): A rare autoimmune disease that affects the optic nerve and spinal cord, causing vision loss, muscle weakness, and other neurological symptoms.
5. Autoimmune encephalitis: A group of conditions characterized by inflammation of the brain, caused by an overactive immune response. Symptoms can include seizures, memory loss, confusion, and behavioral changes.
6. Chronic inflammatory demyelinating polyneuropathy (CIDP): A rare disorder that causes progressive weakness and numbness in the legs and arms due to damage to the nerves' protective covering.

Treatment for autoimmune diseases of the nervous system typically involves medications to suppress the immune system and reduce inflammation, as well as physical therapy and other supportive measures to manage symptoms and maintain function.

Hyperglycemic Hyperosmolar Nonketotic Coma (HHNC) is a serious complication of diabetes, specifically type 2, that occurs when blood glucose levels rise to extremely high levels, typically above 600 mg/dL. This condition is often accompanied by severe dehydration due to excessive urination and an inability to consume adequate fluids.

The term "hyperosmolar" refers to the high concentration of glucose in the blood, which increases the osmolality (or osmotic pressure) of the blood. This can lead to water moving out of cells and into the bloodstream to try to balance out the concentration, causing severe dehydration.

The term "nonketotic" means that there is no significant production of ketone bodies, which are produced when the body breaks down fat for energy in the absence of sufficient insulin. This differentiates HHNC from diabetic ketoacidosis (DKA), another serious complication of diabetes.

The "coma" part of the term refers to the fact that HHNC can cause altered mental status, ranging from confusion and disorientation to coma, due to the effects of dehydration and high blood glucose levels on the brain.

HHNC is a medical emergency that requires immediate treatment in a hospital setting. Treatment typically involves administering fluids to rehydrate the body, insulin to lower blood glucose levels, and addressing any other underlying conditions or complications. If left untreated, HHNC can be life-threatening.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

Hyperemesis Gravidarum is a severe form of nausea and vomiting in pregnancy that is more extreme than the typical morning sickness. It's characterized by persistent vomiting, dehydration, weight loss, and electrolyte imbalance. If left untreated, it can lead to serious complications for both the mother and the baby. The exact cause is not known, but it may be related to high levels of hormones or other substances in the pregnant woman's body. Treatment often involves hospitalization for rehydration, medication to control vomiting, and nutritional support.

Streptococcal infections are a type of infection caused by group A Streptococcus bacteria (Streptococcus pyogenes). These bacteria can cause a variety of illnesses, ranging from mild skin infections to serious and potentially life-threatening conditions such as sepsis, pneumonia, and necrotizing fasciitis (flesh-eating disease).

Some common types of streptococcal infections include:

* Streptococcal pharyngitis (strep throat) - an infection of the throat and tonsils that can cause sore throat, fever, and swollen lymph nodes.
* Impetigo - a highly contagious skin infection that causes sores or blisters on the skin.
* Cellulitis - a bacterial infection of the deeper layers of the skin and underlying tissue that can cause redness, swelling, pain, and warmth in the affected area.
* Scarlet fever - a streptococcal infection that causes a bright red rash on the body, high fever, and sore throat.
* Necrotizing fasciitis - a rare but serious bacterial infection that can cause tissue death and destruction of the muscles and fascia (the tissue that covers the muscles).

Treatment for streptococcal infections typically involves antibiotics to kill the bacteria causing the infection. It is important to seek medical attention if you suspect a streptococcal infection, as prompt treatment can help prevent serious complications.

When chorea is serious, slight movements will become thrashing motions; this form of severe chorea is referred to as ballism, ... The term hemichorea refers to chorea of one side of the body, such as chorea of one arm but not both (analogous to ... Historically, choreas like Huntington disease and Sydenham's chorea were called Saint Vitus' dance, related to a series of ... There is no standard course of treatment for chorea. Treatment depends on the type of chorea and the associated disease. ...
... is a species of fly in the family Lonchaeidae. It is found in the Palearctic. The larva develops in cow dung. ... Images representing Lonchaea chorea at BOLD v t e (Articles with short description, Short description is different from ... On the Life-history of Lonchaca chorea, Fabricius". Transactions of the Entomological Society of London. 61: 314-322. Retrieved ...
This disease is also characterized by the presence of a few different movement disorders including chorea, dystonia etc. Chorea ... Chorea-acanthocytosis (ChAc, also called choreoacanthocytosis) is a rare hereditary disease caused by a mutation in a gene that ... Chorea-acanthocytosis is a very complex autosomal recessive adult-onset neurodegenerative disorder. It often shows itself as a ... Patients with chorea-acanthocytosis should undergo a cardiac evaluation every five years to look for cardiomyopathy.[citation ...
... is a rare type of chorea which presents with involuntary abnormal movement, characterized by abrupt, brief, ... It has been suggested that use of oral contraceptives is an infrequent cause of chorea. A patient developed this chorea with no ... Chorea Zegart, K. N.; Schwarz, R. H. (1968). "Chorea gravidarum". Obstetrics and Gynecology. 32 (1): 24-7. PMID 5742087. ... Chorea Gravidarum at eMedicine Axley, John (1972). "Rheumatic chorea controlled with haloperidol". The Journal of Pediatrics. ...
... is a Palearctic species of cranefly in the family Limoniidae. It is found in a wide range of habitats and ... Fauna Europaea "Dicranomyia (Dicranomyia) chorea (Meigen, 1818) , Fauna Europaea". Stubbs, A. and Kramer, J, 2016 A Key to the ...
... is primarily seen in children. As with rheumatic fever, Sydenham's chorea is seen more often in less affluent ... Sydenham's chorea, also known as rheumatic chorea, is a disorder characterized by rapid, uncoordinated jerking movements ... but Sydenham's chorea is one of the exclusion criteria. PANDAS can present with chorea but more typically there are tics or ... "Fever therapy in chorea and in rheumatic carditis with and without chorea". The Journal of Laboratory and Clinical Medicine. 21 ...
Chorea or Choreia may also refer to: Choreia, an ancient Greek dance Chorea minor Chorea gravidarum, a chorea that occurs as a ... Look up chorea or choreá in Wiktionary, the free dictionary. Chorea is an abnormal involuntary movement disorder. ... a combination of chorea and athetosis All pages with titles containing Chorea Cholera, an infection of the small intestine by ... This disambiguation page lists articles associated with the title Chorea. If an internal link led you here, you may wish to ...
... (BHC), also known as benign familial chorea, is a rare autosomal dominant neurogenetic syndrome. It ... Chorea Huntington's disease Peall, Kathryn; Kurian, Manju (June 14, 2015). "Benign Hereditary Chorea: An Update". Tremor Other ... Benign Hereditary Chorea is an autosomal dominant disorder. It is believed to be caused by a single-nucleotide substitution in ... Benign Hereditary Chorea is characterized by early onset of an abnormal gait, speech articulation difficulties, anxiety, and ...
On Chorea. Huntington, George. On Chorea. "Dr. George Huntington and the Disease Bearing His Name". 2006-07-18. Archived from ... During this period, he was able to better observe the cases of hereditary chorea, which he had seen for the first time with his ... On February 15, 1872, George Huntington gave his classic presentation on chorea to the Meigs and Mason Academy of Medicine in ... Wikisource has original text related to this article: On Chorea Wikiquote has quotations related to William Osler, including ...
Chorea acanthocytosis is characterised by dystonia, chorea and progressive cognitive, behavioural changes and seizures. ... Chorea acanthocytosis is an autosomal recessive disorder caused by mutations in the VPS13A, also called CHAC, on chromosome ... "Chorea In Children." EMedicine - Medical Reference (2008). 23 September 2008. 8 February 2010. Rampoldi L, Danek A, Monaco AP ( ... There are about 500-1,000 cases of chorea acanthocytosis worldwide and it is not specific to any particular ethnic group. ...
"Chorea-acanthocytosis". Genetic Home Reference. U.S. National Library of Medicine, National Institutes of Health. May 2008. ...
For example, Thomas Sydenham explored chorea in the 17th century, in which his description of symptoms of what he named chorea ... Sydenham's chorea was often incorrectly referred to as St. Vitus' dance. The research that had previously been done was limited ... "Sydenham Chorea , National Institute of Neurological Disorders and Stroke". Retrieved 2022-07-25. "Die ... Brabazon, A. B. (1880). "Chorea Sancti Viti, Or St. Vitus's Dance: Its Treatment With The Bath Mineral Waters". The British ...
Huntington's chorea). Deutetrabenazine, an isotopic isomer of tetrabenazine, was approved by the FDA for tardive dyskinesia in ...
Dystonias, paroxysmal dyskinesias, chorea, other genetic conditions, and secondary causes of tics should be ruled out in the ... Tics must be distinguished from movements of disorders such as chorea, dystonia and myoclonus; the compulsions of obsessive- ... Sydenham's chorea; idiopathic dystonia; and genetic conditions such as Huntington's disease, neuroacanthocytosis, pantothenate ...
Chorea (disease) Myoclonus Dystonia Torsion dystonia Idiopathic dystonia Chromosomal abnormalities Citrullinemia Down syndrome ... Sydenham's chorea; idiopathic dystonia; and genetic conditions such as Huntington's disease, neuroacanthocytosis, pantothenate ... Schizophrenia Tuberous sclerosis Wilson's disease XYY syndrome Encephalitis Mycoplasma pneumoniae Sydenham's chorea Pervasive ...
Lanska, D. J. (2000). "George Huntington (1850-1916) and hereditary chorea". Journal of the History of the Neurosciences. 9 (1 ... ISBN 978-1-84724-008-8. Huntington, G. (1872-04-13). "On Chorea". Medical and Surgical Reporter of Philadelphia. 26 (15): 317- ... Vale, Thiago Cardoso; Cardoso, Francisco (2015). "Chorea: A journey through history". Tremor and Other Hyperkinetic Movements. ...
Azar S, Ramjiani A, Van Gerpen JA (April 2005). "Ciprofloxacin-induced chorea". Mov. Disord. 20 (4): 513-4, author reply 514. ... myoclonus and chorea like), visual hallucination in two elderly patients]. Nippon Ronen Igakkai Zasshi (in Japanese). 36 (3): ... Myoclonus and Chorea Like), Visual Hallucination in Two Elderly Patients" [Levofloxacin-induced neurological adverse effects ...
"Sydenham Chorea Information Page , National Institute of Neurological Disorders and Stroke". Retrieved 30 ... Bed rest may be sufficient treatment for mild cases of Sydenham chorea. In those with deep vein thrombosis early movement ...
CSMF Chorea, hereditary benign; 118700; NKX2-1 Choreoacanthocytosis; 200150; VPS13A Choreoathetosis, hypothyroidism, and ...
Ørbeck, Alf L; Quelprud, Thordar (1954). Setesdalsrykka (Chorea progressiva hereditaria). Oslo: Jacob Dybwad. (Articles with ...
Chorea is another condition which results from damage to the basal ganglia. Similar to athetosis, it results from mutations ... Considering the etiology of both disorders are fairly similar, it comes as no surprise that chorea and athetosis can and ... Chorea Dyskinesia Dystonia Pupillary athetosis Walker, Kenneth H (1990). "Ch. 70 Involuntary Movements". Clinical Methods: The ... Bhidayasiri, R; Truong, DD (September 2004). "Chorea and related disorders". Postgraduate Medical Journal. 80 (947): 527-34. ...
In 2010 the group made the EP Chorea. Songs from the EP can be downloaded free from SoundCloud. In 2010 and 2011 the group ... ". "Critique de l'EP Chorea". Richard, Philippe. "Depth Affect : 'Draft Battle' disponible". Archived from the original on ...
... the video appears to deal with the concept of Chorea as in the film the cast imitate the effects of Chorea. The band then ... Later on they released the third and final single off the album, "Chorea", was released for Record Store Day. A short film was ... "Esben and the Witch - Chorea". Matadorrecs. Retrieved 19 May 2013. "East Coast USA March 2011". Esben and the Witch Facebook. ... "Chorea" - 4:25 "Warpath" - 4:28 "Battlecry/Mimicry" - 1:20 "Eumenides" - 6:12 "Swans" - 4:36 Bonus disc "Lucia, at the ...
Vitus' Dance was diagnosed, in the 17th century, as Sydenham chorea. Dancing mania has also been known as epidemic chorea: 125 ... A disease of the nervous system, chorea is characterized by symptoms resembling those of dancing mania,: 134 which has also ... Giménez-Roldán S, Aubert G (June 2007). "Hysterical chorea: Report of an outbreak and movie documentation by Arthur Van ... ISBN 978-1-4191-5424-9. "NINDS Sydenham Chorea Information Page". NINDS. US: NIH. Retrieved 4 September 2010. Schullian, DM ( ...
"The Bradshaw Lecture ON CHOREA". The Lancet. 196 (5074): 1081-1086. 1920. doi:10.1016/S0140-6736(01)19959-9. "Bradshaw Lecture ... Chorea 1918 William Aldren Turner, Neuroses and psychoses of war 1917 Ernest Septimus Reynolds, Causes of Disease 1916 Hector ...
Brain, 1905, 28, 116-338.) A case of Huntington's chorea. (Brain, 1905, 28, 98.) A case of Huntington's chorea. (Brain, 1905, ...
It is useful in the treatment of chorea. Metabolism of nirvanol is stereoselective, with the (S)- enantiomer undergoing roughly ... Ashby HT (February 1930). "Treatment of Chorea by Nirvanol". Archives of Disease in Childhood. 5 (25): 42-3. doi:10.1136/adc. ...
"NINDS Sydenham Chorea Information Page". February 14, 2007. Archived from the original on July 22, 2010. Retrieved May 8, 2012 ...
McHugh, P.R; Folstein, M.F (1975). "Psychiatric syndromes in Huntington's chorea". Psychiatric Aspectes of Neurological Disease ...
Among other things Sydenham is credited with the first diagnosis of scarlatina and with the modern definition, of chorea (in ... Kushner HI, Cortes D.: Sydenham's chorea. In: Koehler PJ, Bruyn GW, Pearce JMS, eds. Neurological Eponyms. Oxford - New York, ... Pearce, J.M.S. (1995). "Thomas Sydenham and Richard Bright on chorea". J. Neurol. Neurosurg. Psychiatry. 58 (3): 319. doi: ... Sydenham's chorea, also known as St Vitus' Dance. To him is attributed the prescient dictum, "A man is as old as his arteries ...
When chorea is serious, slight movements will become thrashing motions; this form of severe chorea is referred to as ballism, ... The term hemichorea refers to chorea of one side of the body, such as chorea of one arm but not both (analogous to ... Historically, choreas like Huntington disease and Sydenhams chorea were called Saint Vitus dance, related to a series of ... There is no standard course of treatment for chorea. Treatment depends on the type of chorea and the associated disease. ...
Chorea-acanthocytosis is primarily a neurological disorder that affects movement in many parts of the body. Explore symptoms, ... Chorea-acanthocytosis is primarily a neurological disorder that affects movement in many parts of the body. Chorea refers to ... In addition to chorea, another common feature of chorea-acanthocytosis is involuntary tensing of various muscles (dystonia), ... Nearly half of all people with chorea-acanthocytosis have seizures.. Individuals with chorea-acanthocytosis may develop ...
Sydenham chorea is a movement disorder that occurs after infection with specific bacteria called group A streptococcus. ... Sydenham chorea is a movement disorder that occurs after infection with specific bacteria called group A streptococcus. ... Vitus dance; Chorea minor; Rheumatic chorea; Rheumatic fever - Sydenham chorea; Strep throat - Sydenham chorea; Streptococcal ... Sydenham chorea is a major sign of acute RF. The person may currently or recently have had the disease. Sydenham chorea may be ...
This is not an etiologically or pathologically distinct morbid entity but a generic term for chorea of any cause starting ... is the term given to chorea occurring during pregnancy. ... Chorea gravidarum (CG) is the term given to chorea occurring ... Of afflicted women, 60% previously had chorea and a family history of transient chorea is not unusual. When occurring with ... encoded search term (Chorea Gravidarum) and Chorea Gravidarum What to Read Next on Medscape ...
Nonhereditary causes of chorea, such as infectious chorea in the course of acute manifestations of bacterial or aseptic ... Hagiwara K, Tominaga K, Okada Y, Kido M, Yamasaki R, Shida N, Post-streptococcal chorea in an adult with bilateral striatal ... West Nile virus (WNV) infection presenting as acute chorea. Travel Med Infect Dis. 2012;10:52-3. DOIPubMedGoogle Scholar ... Chorea arises deep in the basal ganglia; high-definition MRI demonstrates caudate atrophy (7). In patients with TBE, MRI may ...
Chorea involves irregular, sometimes jerky or writhing movements of the face and limbs that cannot be controlled. ... Chorea is not in itself a disease; rather, it is a symptom of another neurological issue. Chorea has many underlying causes, ... Chorea involves irregular, sometimes jerky or writhing movements of the face and limbs that cannot be controlled. ... Because the causes of chorea are so varied, treatments can vary widely, but may include medication, physical therapy or surgery ...
Neurocrine Biosciences Presents Phase 3 Data for KINECT-HD Study Evaluating Valbenazine for Chorea Associated with Huntington ... Valbenazine Met the Primary Endpoint of Significant (p,0.0001) Improvement in Chorea Severity versus Placebo as Measured by the ... About Chorea Associated with Huntington Disease. Huntington disease (HD) is a hereditary progressive, ultimately fatal ... The KINECT-HD study met its primary endpoint of change in chorea severity using the TMC score of the UHDRS® from screening ...
Growth hormone and prolactin response to bromocriptine in patients with Huntingtons chorea. ... Growth hormone and prolactin response to bromocriptine in patients with Huntingtons chorea. ...
You searched for: Author Khunger, Arjun ✖ Remove constraint Author: Khunger, Arjun Subject Chorea ✖ Remove constraint Subject: ...
Unilateral chorea linked to cavernous haemangioma involving the putamen improved by surgery ... Unilateral chorea linked to cavernous haemangioma involving the putamen improved by surgery ...
... Author: Peikert, Kevin; ... Targeting Lyn Kinase in Chorea-Acanthocytosis: A Translational Treatment Approach in a Rare Disease. DSpace Repository. Login ...
The most of our practitioners have had experience with the use of macrotys, in the treatment of chorea. When this condition ...
Chorea can commence at any age. In children, postpump chorea and infectious, inflammatory, and striatal lesions may account for ... encoded search term (Chorea in Adults) and Chorea in Adults What to Read Next on Medscape ... The most well-studied choreatic syndrome is Huntington chorea; therefore, the pathophysiology of HD as it applies to chorea is ... Although no data are available regarding the incidence of chorea, the incidences of several disorders in which chorea is the ...
Premilife can treat you with natural homeopathic treatment for chorea minor sydenham chorea. ...
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Chorea, Athetosis, and Hemiballismus - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals ... Chorea in patients > 60 should not be assumed to be senile chorea but should be thoroughly evaluated to identify the cause (eg ... Chorea gravidarum occurs during pregnancy, often in patients who have had rheumatic fever. Chorea usually begins during the 1st ... Sydenham chorea and chorea due to infarcts of the caudate nucleus often lessen over time without treatment. ...
GENERALIZED HYPOTONIA and CHOREA related symptoms, diseases, and genetic alterations. Get the complete information with our ... Generalized hypotonia, and Chorea. .site-footer{margin-bottom:80px}. If you liked this article maybe you will also find ...
Austedo Inspires HD Chorea Patients to Grab Hold of Every ...
FRISON, Thirzá Baptista et al. Neuropsychological profile of an adult with Chorea-Acanthocytosis: a case study. Cuad. ... Palabras clave : Chorea-acanthocytosis; Neuroacanthocytosis; cognition; neuropsychological assessment; Theory of Mind; case ...
Choreas Sacras Veterum Christianorum Sigilatim Erffurti & Arnstadiae institutas Epistola Gratulatoria ad Dn. Joh. Gotofredum ...
Snapshot: What is Chorea? January 12, 2024 Chorea is a neurological disorder characterized by involuntary, unusual, and abrupt ... The word "chorea" is originated from the Greek word "choreia," which means "dance", accurately depicting the jerky, dance-like ...
Huntingtons Chorea (1980 Film). Subject. Medical sciences. Distribution. Film (16mm). Presents the medical, social and genetic ... aspects of Huntingtons chorea as exemplified in three families. Brief discussion on the patho-physiological changes in the ...
Chorea, also called Sydenhams chorea or St. Vitus dance, is the major central nervous system manifestation. Chorea is a ... Chorea often appears after the other manifestations of acute rheumatic fever. It also can appear as the only manifestation of ... acute rheumatic fever can be considered in cases of chorea and indolent, chronic carditis despite the lack of group A ...
As a result of sharing a single placenta, the blood supplies of monochorionic twin fetuses can become connected, so that they share blood circulation: although each fetus uses its own portion of the placenta, the connecting blood vessels within the placenta allow blood to pass from one twin to the other. It is thought that most monochorionic placentae have these "shared connections" that cross the placenta, with the net flow volumes being equal between them. This state is sometimes referred to as "flow balance". When the placenta has deep vein-artery connection, this can cause blood flow to become unbalanced.[4] Depending on the number, type and direction of the interconnecting blood vessels (anastomoses), blood can be transferred disproportionately from one twin (the "donor") to the other (the "recipient"), due to a state of "flow imbalance" imparted by new blood vessel growth across the placental "equator", the line that divides each babys proportion of the shared placenta. This state of ...
Chorea Polonica / Diomedes Cato -- Susanna videns / Adam Jarzebski -- Magnificat / Jacek Rozycki.. Call Number. *LZR 66291. ...
Te gustaría hacer una donación deducible de impuestos y ser parte de una investigación de vanguardia y de una atención médica que transforma la medicina?. ...
Chorea. *Dystonia. *Myoclonus. *Sleep disorders, including REM sleep behavior disorder. *Restless legs syndrome ...
Lumbar Puncture Alleviates Chorea in a Patient with Huntingtons Disease and Normal Pressure Hydrocephalus. Peyman Shirani , ...
Chorea-acanthocytosis is closely related to diseases with Parkinsonism, dementia, and ataxia ... Shortly after the gene mutated in chorea-acanthocytosis (ChAc) was discovered in 2001, Antonio Velayos-Baeza from the Monaco ...
  • Sydenham chorea is a movement disorder that occurs after infection with specific bacteria called group A streptococcus. (
  • Sydenham chorea is caused by an infection with bacteria called group A streptococcus. (
  • Sydenham chorea is a major sign of acute RF. (
  • Sydenham chorea may be the only sign of RF in some people. (
  • Sydenham chorea occurs most often in girls before puberty, but may be seen in boys. (
  • Sydenham chorea usually clears up in a few months. (
  • In rare cases, an unusual form of Sydenham chorea may begin later in life. (
  • Sydenham chorea and chorea due to infarcts of the caudate nucleus often lessen over time without treatment. (
  • The absence of supporting evidence of preceding streptococcal infection should make the diagnosis doubtful, except in Sydenham chorea or low-grade carditis when rheumatic fever is first discovered after a long latent period from the antecedent infection. (
  • These 'dance-like' movements of chorea often occur with athetosis, which adds twisting and writhing movements. (
  • Any discussion of chorea must also address the related terms athetosis, choreoathetosis, and ballism (also known as ballismus). (
  • Choreoathetosis is essentially an intermediate form (ie, a bit more rapid than the usual athetosis, slower than the usual chorea, or a mingling of chorea and athetosis within the same patient at different times or in different limbs). (
  • Given that the only difference between chorea, choreoathetosis, and athetosis is the speed of movement, some neurologists argue that the term athetosis is unnecessary and even confusing. (
  • Athetosis (slow chorea) is nonrhythmic, slow, writhing, sinuous movements predominantly in distal muscles, often alternating with postures of the proximal limbs. (
  • many experts believe that when they occur together (as choreoathetosis), athetosis is a dystonia superimposed on chorea. (
  • Chorea and athetosis result from impaired inhibition of thalamocortical neurons by the basal ganglia. (
  • This includes dystonia, athetosis, and chorea. (
  • Chorea refers to the involuntary jerking movements made by people with this disorder. (
  • The condition was formerly called Huntington's chorea but was renamed because of the important non-choreic features including cognitive decline and behavioural change. (
  • In addition to chorea, another common feature of chorea-acanthocytosis is involuntary tensing of various muscles (dystonia), such as those in the limbs, face, mouth, tongue, and throat. (
  • Absent subthalamic nucleus inhibition enhances motor activity through the motor thalamus, resulting in abnormal involuntary movements such as dystonia, chorea, and tics. (
  • Sydenham's chorea occurs as a complication of streptococcal infection. (
  • Twenty percent (20%) of children and adolescents with rheumatic fever develop Sydenham's chorea as a complication. (
  • Historically, choreas like Huntington disease and Sydenham's chorea were called Saint Vitus' dance, related to a series of social phenomena of the same name. (
  • Chorea, also called Sydenham's chorea or St. Vitus dance, is the major central nervous system manifestation. (
  • Chorea gravidarum refers to choreic symptoms that occur during pregnancy. (
  • Chorea gravidarum (CG) is the term given to chorea occurring during pregnancy. (
  • Rheumatic fever is no longer a major cause of chorea gravidarum (CG) and the pathophysiology of CG in current times is unclear. (
  • Movement disorders rarely occur during reproductive years, therefore, clinicians are not very familiar with chorea gravidarum (CG). (
  • Chorea gravidarum occurs during pregnancy, often in patients who have had rheumatic fever. (
  • In 2004, Miranda et al reported of a case of chorea associated with the use of the oral contraceptives, in which anti-basal ganglia antibodies were detected, suggesting a possible immunological basis to the pathogenesis of this disorder. (
  • We describe a case of chorea in the course of TBE in a man in Poland. (
  • Treatment depends on the type of chorea and the associated disease. (
  • Those with a more severe type of chorea, choreiform, make movements that can be wild and violent, that are large in magnitude (ballism). (
  • SAN DIEGO , April 1 , 2022 /PRNewswire/ -- Neurocrine Biosciences, Inc. , (Nasdaq: NBIX) today announced results from the Phase 3 KINECT-HD study, which demonstrated once-daily administration of valbenazine was associated with significant improvement in chorea associated with Huntington disease (HD) compared with placebo. (
  • Presentation of these positive data of valbenazine for chorea in Huntington disease represent a major step forward in our commitment to offering the community a potential new treatment option," said Eiry W. Roberts, M.D., Chief Medical Officer at Neurocrine Biosciences. (
  • In a busy movement disorder center, levodopa-induced chorea is the most common movement disorder, followed by Huntington disease (HD). (
  • They argue a simpler nomenclature would delineate fast, intermediate, and slow chorea. (
  • The ad hoc Committee on Classification of the World Federation of Neurology has defined chorea as "a state of excessive, spontaneous movements, irregularly timed, non-repetitive, randomly distributed and abrupt in character. (
  • Unlike ataxia, which affects the quality of voluntary movements, or Parkinsonism, which is a hindrance of voluntary movements, the movements of chorea and ballism occur on their own, without conscious effort. (
  • this form of severe chorea is referred to as ballism, or ballismus. (
  • Ballism or ballismus is considered a very severe form of chorea in which the movements have a violent, flinging quality. (
  • Currently, ballism should be viewed as a severe form of chorea. (
  • Other genetic causes of chorea are rare. (
  • Chorea has many underlying causes, including but not limited to head trauma, infection, genetic conditions or inflammation. (
  • Presents the medical, social and genetic aspects of Huntington's chorea as exemplified in three families. (
  • Chorea involves irregular, sometimes jerky or writhing movements of the face and limbs that cannot be controlled. (
  • Chorea often appears after the other manifestations of acute rheumatic fever. (
  • Chorea-acanthocytosis is primarily a neurological disorder that affects movement in many parts of the body. (
  • Chorea is a neurological disorder characterized by involuntary, unusual, and abrupt movements of the body that appear to be out of control and without purpose. (
  • Chorea is a neurological disorder characterized by abrupt, purposeless, non-rhythmic, involuntary movements that is often associated with muscle weakness and emotional lability. (
  • A tumor or an infarct in the striatum (caudate or putamen) can cause acute unilateral chorea (hemichorea) on the opposite side of the body. (
  • Hemiballismus may be considered a severe form of chorea. (
  • Psychological symptoms may precede or accompany this acquired chorea and may be relapsing and remitting. (
  • The signs and symptoms of chorea-acanthocytosis usually begin in early to mid-adulthood. (
  • Also common are attempts by patients to mask the chorea by voluntarily augmenting the choreiform movements with semipurposeful movements. (
  • Chorea can affect many body parts and cause issues with movement, speech and swallowing;Choreiform movements slow down during sleep. (
  • Chorea involves both proximal and distal muscles. (
  • citation needed] Huntington's disease is a neurodegenerative disease and most common inherited cause of chorea. (
  • One medication (Oral), Tetrabenazine (Xenazine), is FDA approved to treat Chorea associated with Huntington's disease but has not been specifically studied in people who have chorea due to cerebral palsy. (
  • What is the difference between chorea and Huntington's disease? (
  • eg, risperidone , olanzapine ), and dopamine -depleting drugs (eg, deutetrabenazine , reserpine [no longer available in US], tetrabenazine ) can be used to treat chorea. (
  • A drug called tetrabenazine can help to ease chorea, for example. (
  • therefore, the pathophysiology of HD as it applies to chorea is the focus of the discussion that follows. (
  • Growth hormone and prolactin response to bromocriptine in patients with Huntington's chorea. (
  • Patients with chorea exhibit motor impersistence (ie, they cannot maintain a sustained posture). (
  • Decreased Na + /K + ATPase Expression and Depolarized Cell Membrane in Neurons Differentiated from Chorea-Acanthocytosis Patients. (
  • is the most common degenerative disorder causing chorea. (
  • The term hemichorea refers to chorea of one side of the body, such as chorea of one arm but not both (analogous to hemiballismus). (
  • Chorea (or choreia, occasionally) is an abnormal involuntary movement disorder, one of a group of neurological disorders called dyskinesias. (
  • The broader spectrum of paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection can cause chorea and are collectively referred to as PANDAS. (
  • Intensive propulsion, involuntary muscle movements (limbs and face), muscle weakness of left upper and lower limbs, and "walk dance" in 38-year-old man with tick-borne encephalitis and chorea, Poland. (
  • 60 should not be assumed to be senile chorea but should be thoroughly evaluated to identify the cause (eg, toxic, metabolic, autoimmune, paraneoplastic, drug-induced). (
  • Chorea is characterized by brief, semi-directed, irregular movements that are not repetitive or rhythmic, but appear to flow from one muscle to the next. (
  • Chorea - Identified by movements made that are not with purpose, that are quick, abrupt, without a pattern and not predictable. (
  • Loss of cells (atrophy) in certain brain regions is the major cause of the neurological problems seen in people with chorea-acanthocytosis. (
  • Fluid-attenuated inversion recovery magnetic resonance imaging of the brain of a 38-year-old man with tick-borne encephalitis and chorea. (
  • Neuropathological findings in chorea-acanthocytosis: new insights into mechanisms underlying parkinsonism and seizures. (
  • This is not an etiologically or pathologically distinct entity but rather a generic term for chorea of any cause starting during pregnancy. (
  • In 1950, Beresford and Graham postulated that, "It may be that pregnancy lowers the resistance of a patient who is inherently susceptible to chorea. (
  • Chorea is an involuntary abnormal movement, characterized by abrupt, brief, nonrhythmic, nonrepetitive movement of any limb, often associated with nonpatterned facial grimaces. (
  • Clinicians should seek and treat the cause of chorea whenever possible. (
  • If chorea does not subside after several weeks of metabolic control, clinicians should check for another cause such as stroke. (
  • Thus, chorea is said to be a hyperkinetic movement disorder. (
  • [ 11 , 12 ] Oral contraceptives may activate the same high estrogen state mechanism of CG leading to chorea and further supporting the role of estrogen in CG. (
  • Another pathologic hypothesis is related to hormonal mediation, particularly estrogen, given there is an increase in chorea cases among young women on oral contraceptives. (
  • Behavioral changes are a common feature of chorea-acanthocytosis and may be the first sign of this condition. (