DiseasesChemicals and DrugsPsychiatry and Psychology
ChoreaHuntington DiseaseRheumatic FeverChorea GravidarumAnti-Dyskinesia AgentsAutoimmune Diseases of the Nervous SystemHyperglycemic Hyperosmolar Nonketotic Coma
Chorea
Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
Huntington Disease
A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Rheumatic Fever
A febrile disease occurring as a delayed sequela of infections with STREPTOCOCCUS PYOGENES. It is characterized by multiple focal inflammatory lesions of the connective tissue structures, such as the heart, blood vessels, and joints (POLYARTHRITIS) and brain, and by the presence of ASCHOFF BODIES in the myocardium and skin.
Chorea Gravidarum
A rare movement disorder developed during PREGNANCY, characterized by involuntary jerky motion (CHOREA) and inability to maintain stable position of body parts (ATHETOSIS). RHEUMATIC FEVER and collagen vascular disorders are frequently associated with this disease. Chorea may vary from mild to severe and occurs in approximately 1 per 2,000 to 3,000 pregnancies. (From Md Med J 1997 Sep;46(8):436-9)
Anti-Dyskinesia Agents
Drugs used in the treatment of movement disorders. Most of these act centrally on dopaminergic or cholinergic systems. Among the most important clinically are those used for the treatment of Parkinson disease (ANTIPARKINSON AGENTS) and those for the tardive dyskinesias.
Autoimmune Diseases of the Nervous System
Disorders caused by cellular or humoral immune responses primarily directed towards nervous system autoantigens. The immune response may be directed towards specific tissue components (e.g., myelin) and may be limited to the central nervous system (e.g., MULTIPLE SCLEROSIS) or the peripheral nervous system (e.g., GUILLAIN-BARRE SYNDROME).
Hyperglycemic Hyperosmolar Nonketotic Coma
A serious complication of TYPE 2 DIABETES MELLITUS. It is characterized by extreme HYPERGLYCEMIA; DEHYDRATION; serum hyperosmolarity; and depressed consciousness leading to COMA in the absence of KETOSIS and ACIDOSIS.

Familial essential ("benign") chorea. (1/216)

A family is described with essential non-progressive chorea occurring in an autosomal dominant inheritance pattern over four generations. A few families with an apparently similar disorder have been reported previously. This condition is characterized by early childhood onset of chorea which is not progressive and is compatible with a long life. It is not associated with dementia, seizures, rigidity, or ataxia. It is a socially embarrassing condition and may, sometimes, be associated with behavioural problems and learning difficulties. For genetic counselling, it is important to distinguish this disorder from Huntington's disease and other hereditary disorders associated with chorea.  (+info)

Rheumatic chorea in northern Australia: a clinical and epidemiological study. (2/216)

To describe the epidemiology and clinical features of Sydenham's chorea in the Aboriginal population of northern Australia a review was conducted of 158 episodes in 108 people: 106 were Aborigines, 79 were female, and the mean age was 10.9 years at first episode. Chorea occurred in 28% of cases of acute rheumatic fever, carditis occurred in 25% of episodes of chorea, and arthritis in 8%. Patients with carditis or arthritis tended to have raised acute phase reactants and streptococcal serology. Two episodes lasted at least 30 months. Mean time to first recurrence of chorea was 2.1 years compared with 1.2 years to second recurrence. Established rheumatic heart disease developed in 58% of cases and was more likely in those presenting with acute carditis, although most people who developed rheumatic heart disease did not have evidence of acute carditis with chorea. Differences in the patterns of chorea and other manifestations of acute rheumatic fever in different populations may hold clues to its pathogenesis. Long term adherence to secondary prophylaxis is crucial following all episodes of acute rheumatic fever, including chorea, to prevent recurrence.  (+info)

Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics. (3/216)

Anticonvulsants cause dyskinesias more commonly than has been appreciated. Diphenylhydantoin (DPH), carbamazepine, primidone, and phenobarbitone may cause asterixis. DPH, but not other anticonvulsants, may cause orofacial dyskinesias, limb chorea, and dystonia in intoxicated patients. These dyskinesias are similar to those caused by neuroleptic drugs and may be related to dopamine antagonistic properties possessed by DPH.  (+info)

Paroxysmal kinesigenic choreoathetosis associated with frontotemporal arachnoid cyst--case report. (4/216)

A 17-year-old male presented with paroxysmal kinesigenic choreoathetosis (PKC) associated with frontotemporal arachnoid cyst. Xenon-133 single photon emission computed tomography detected a slight but equivocal decrease in regional cerebral blood flow in the vicinity of basal ganglia associated with the PKC episodes. PKC continued after surgical removal of the cyst but was well controlled by oral administration of carbamazepine. Whether the pathogenesis of symptomatic PKC was associated with the cortical lesion could not be determined in the present case.  (+info)

Intracortical inhibition of the motor cortex is normal in chorea. (5/216)

Intracortical inhibition of the motor cortex was investigated using a paired pulse magnetic stimulation method in 14 patients with chorea caused by various aetiologies (six patients with Huntington's disease, one with chorea acanthocytosis, a patient with systemic lupus erythematosus with a vascular lesion in the caudate, three with senile chorea and three with chorea of unknown aetiology). The time course and amount of inhibition was the same in the patients as in normal subjects, suggesting that the inhibitory mechanisms of the motor cortex studied with this method are intact in chorea. This is in striking contrast with the abnormal inhibition seen in patients with Parkinson's disease or focal hand dystonia, or those with a lesion in the putamen or globus pallidus. It is concluded that the pathophysiological mechanisms responsible for chorea are different from those producing other involuntary movements.  (+info)

Movement disorders caused by brain tumours. (6/216)

Movement disorders are uncommon presenting features of brain tumours. Early recognition of such lesions is important to arrest further deficit. We treated seven patients with movement disorders secondary to brain tumours over a period of seven years. Only two of these were intrinsic thalamic tumours (astrocytomas) while the rest were extrinsic tumours. The intrinsic tumours were accompanied by hemichorea. Among the extrinsic tumours, there was one pituitary macroadenoma with hemiballismus and four meningiomas with parkinsonism. Symptoms were unilateral in all patients except one with anterior third falcine meningioma who had bilateral rest tremors. There was relief in movement disorders observed after surgery. Imaging by computed tomography or magnetic resonance imaging is mandatory in the evaluation of movement disorders, especially if the presentation is atypical, unilateral and/or accompanied by long tract signs.  (+info)

From off-period dystonia to peak-dose chorea. The clinical spectrum of varying subthalamic nucleus activity. (7/216)

The effect of chronic bilateral high-frequency stimulation of the subthalamic nucleus (STN) on levodopa-induced dyskinaesias was investigated in eight patients with fluctuating Parkinson's disease complicated by functionally disabling off-period dystonia. All of the patients also had severe diphasic and peak-dose chorea, so that it was possible to study the effect of high-frequency stimulation on the different types of levodopa-induced dyskinaesias. Off-period fixed dystonia was reduced by 90% and off-period pain by 66%. After acute levodopa challenge, high-frequency stimulation of the STN reduced diphasic mobile dystonia by 50% and peak-dose choreic dyskinaesias by 30%. The effect of bilateral high-frequency stimulation of the STN on the Unified Parkinson's Disease Rating Scale motor score had the same magnitude as the preoperative effect of levodopa. This allowed the levodopa dose to be reduced by 47%. The combination of reduced medication and continuous high-frequency stimulation of the STN reduced the duration of on-period diphasic and peak-dose dyskinaesias by 52% and the intensity by 68%. Acute high-frequency stimulation of the STN mimics an acute levodopa challenge, concerning both parkinsonism and dyskinaesias, and suppresses off-period dystonia. Increasing the voltage can induce repetitive dystonic dyskinaesias, mimicking diphasic levodopa-induced dyskinaesias. A further increase in voltage leads to a shift from a diphasic-pattern dystonia to a peak-dose pattern choreodystonia. Chronic high-frequency stimulation of the STN also mimics the benefit of levodopa on parkinsonism and improves all kinds of levodopa-induced dyskinaesias to varying degrees. Off-period dystonia, associated with neuronal hyperactivity in the STN is directly affected by stimulation and disappears immediately. The effect of chronic high-frequency stimulation of the STN on diphasic and peak-dose dyskinaesias is more complex and is related directly to the functional inhibition of the STN and indirectly to the replacement of the pulsatile dopaminergic stimulation by continuous functional inhibition of the STN. Chronic high-frequency stimulation of the STN allows a very gradual increase in stimulation parameters with increasing beneficial effect on parkinsonism while reducing the threshold for the elicitation of stimulation-induced dyskinaesias. In parallel with improvement of parkinsonism, the levodopa dose can be gradually decreased. As diphasic dystonic dyskinaesias are improved to a greater degree than peak-dose dyskinaesias, both direct and indirect mechanisms may be involved. Peak-dose choreatic dyskinaesias, associated with little evidence of parkinsonism and thus with low neuronal activity in the STN, are improved, mostly indirectly. Fixed off-period dystonia, mobile diphasic dystonia and peak-dose choreodystonia seem to represent a continuous clinical spectrum reflecting a continuous spectrum of underlying activity patterns of STN neurons.  (+info)

Paroxysmal kinesigenic choreoathetosis locus maps to chromosome 16p11.2-q12.1. (8/216)

Paroxysmal kinesigenic choreoathetosis (PKC), the most frequently described type of paroxysmal dyskinesia, is characterized by recurrent, brief attacks of involuntary movements induced by sudden voluntary movements. Some patients with PKC have a history of infantile afebrile convulsions with a favorable outcome. To localize the PKC locus, we performed genomewide linkage analysis on eight Japanese families with autosomal dominant PKC. Two-point linkage analysis provided a maximum LOD score of 10.27 (recombination fraction [theta] =.00; penetrance [p] =.7) at marker D16S3081, and a maximum multipoint LOD score for a subset of markers was calculated to be 11.51 (p = 0.8) at D16S3080. Haplotype analysis defined the disease locus within a region of approximately 12.4 cM between D16S3093 and D16S416. P1-derived artificial chromosome clones containing loci D16S3093 and D16S416 were mapped, by use of FISH, to 16p11.2 and 16q12.1, respectively. Thus, in the eight families studied, the chromosomal localization of the PKC critical region (PKCR) is 16p11.2-q12.1. The PKCR overlaps with a region responsible for "infantile convulsions and paroxysmal choreoathetosis" (MIM 602066), a recently recognized clinical entity with benign infantile convulsions and nonkinesigenic paroxysmal dyskinesias.  (+info)

Sydenhams Chorea - SafeSpot
Sydenhams chorea is a disease affecting the brain. Chorea refers to a type of abnormal movements. Sydenhams chorea happens after a childhood infection because of a problem with the bodys immune response to a common infection. Sydenhams chorea can develop up to six months after a child has had an infection. Not all children have a clear history of having had an infection by a bacteria called Streptococcus. Most people who might develop Sydenhams chorea do so before they reach eighteen years of age. It is more common in girls than boys. Sydenhams chorea is part of a wider group of inflammatory responses called rheumatic fever, that may involve other parts of the body including the skin, joints and heart.. ...
http://safespot.org.uk/safespotopedia/sydenhams-chorea/
Paroxysmal non-kinesigenic dyskinesia is caused by mutations of the MR-1 mitochondrial targeting sequence. | MRC Mitochondrial...
Paroxysmal non-kinesigenic dyskinesia (PNKD) is an autosomal-dominant movement disorder characterized by attacks of dystonia, chorea and athetosis. Myofibrillogenesis regulator-1 (MR-1), the gene responsible for PNKD, is transcribed into three alternatively spliced forms: long (MR-1L), medium (MR-1M) and small (MR-1S). Two mutations, A7V and A9V, were previously discovered in the N-terminal region common to MR-1L and MR-1S. We now found a third mutation, A33P, in a new PNKD patient in the same region. Contrary to previous reports, we show here that the mutation-free MR-1M is localized in the Golgi apparatus, ER and plasma membrane, whereas both MR-1L and MR-1S isoforms are mitochondrial proteins, imported into the organelle thanks to a 39 amino acid-long, N-terminal mitochondrial targeting sequence (MTS). The MTS, which contains all three PNKD mutations, is then cleaved off the mature proteins before their insertion in the inner mitochondrial membrane. Therefore, mature MR-1S and MR-1L of PNKD ...
http://www.mrc-mbu.cam.ac.uk/publications/1246/paroxysmal-non-kinesigenic-dyskinesia-caused-mutations-mr-1-mitochondrial
Sydenham chorea - Coordinated HealthSydenham chorea - Coordinated Health
Sydenham chorea is a major sign of acute rheumatic fever. The person may currently or recently have had the disease. Sydenham chorea may be the only sign of rheumatic fever in some patients.. Sydenham chorea occurs most often in girls before puberty, but may be seen in boys.. ...
https://coordinatedhealth.com/condition/sydenham-chorea/
Chorea - WikipediaChorea - Wikipedia
The most common acquired causes of chorea are cerebrovascular disease and, in the developing world, HIV infection-usually through its association with cryptococcal disease.[2] Sydenhams chorea occurs as a complication of streptococcal infection. Twenty percent (20%) of children and adolescents with rheumatic fever develop Sydenhams chorea as a complication. It is increasingly rare, which may be partially due to penicillin, improved social conditions, and/or a natural reduction in the bacteria ( Streptococcus ) it has stemmed from. Psychological symptoms may precede or accompany this acquired chorea and may be relapsing and remitting. The broader spectrum of paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection can cause chorea and are collectively referred to as PANDAS.[2] Chorea gravidarum refers to choreic symptoms that occur during pregnancy. If left untreated, the disease resolves in 30% of patients before delivery but, in the other 70%, it persists. The ...
https://en.wikipedia.org/wiki/Chorea
Juvenile hereditary chorea: study of a family with recessive patternJuvenile hereditary chorea: study of a family with recessive pattern
FORTI, Francisco and LIMONGI, João Carlos Papaterra. Juvenile hereditary chorea: study of a family with recessive pattern. Arq. Neuro-Psiquiatr. [online]. 1994, vol.52, n.3, pp.402-405. ISSN 0004-282X. https://doi.org/10.1590/S0004-282X1994000300019.. Report of a family in which the parents are consanguineous and healthy and 4 of their 8 children began with involuntary choreic movements at ages 10 to 14. In all cases the clinical manifestations remained stable troughout the 5-year period of observation. There have been no clinical deterioration and intellectual functions were found to be intact. All patients were submitted to neurologic examination, neuropsychological testing, CT-scan, cerebrospinal fluid analysis, eletroencephalogram , serum copper and ceruloplasmin among other blood tests. These cases were diagnosed as having juvenile hereditary chorea from the typical clinical manifestations and after exclusion of other known causes of chorea. Relevant clinical aspects and possible ...
http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0004-282X1994000300019&lng=en&nrm=iso&tlng=en
DMOZ - Health: Conditions and Diseases: Neurological Disorders: Sydenhams Chorea
Sydenhams Chorea is a disorder that primarily affects children. It is associated with Rheumatic Fever, which is caused by a streptococcus group A bacteria. The disease causes emotional instability, purposeless movements, and muscular weakness. It is also know as St. Vitus Dance.
http://dmoztools.net/Health/Conditions_and_Diseases/Neurological_Disorders/Sydenham%27s_Chorea/
Best 25+ Sydenhams chorea ideas on Pinterest | Headache on left side, Swallowing disorders and Picks diseaseBest 25+ Sydenhams chorea ideas on Pinterest | Headache on left side, Swallowing disorders and Picks disease
Find and save ideas about Sydenhams chorea on Pinterest. | See more ideas about Headache on left side, Swallowing disorders and Picks disease.
https://za.pinterest.com/explore/sydenham
Chorea in Non-Ketotic Hyperglycemia | Medical Research Archives
Chorea is an involuntary, irregular, poorly patterned movement that is associated with a wide variety of illnesses. In this case, we describe a 71-year-old female who presented with choreiform movements after a change to her diabetes medication regimen. The patient was found to have non-ketotic hyperglycemia and was admitted to the hospital for insulin and rehydration. Once the patients blood glucose was controlled, her choreiform movements resolved. MRI showed no abnormal findings. In previous case reports, MRI showed hyperintense lesions in the putamen. Although the pathophysiology behind this finding is unclear, several mechanisms have been hypothesized including dopamine hypersensitivity and GABA depletion. We present this case in order to demonstrate the need to consider non-ketotic hyperglycemia in a patient with new onset choreiform movements without typical MRI findings ...
http://www.journals.ke-i.org/index.php/mra/article/view/59
Paroxysmal non-kinesigenic dyskinesia characterised by dystonia in a crossbred dog | Veterinary Record Case Reports
If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patients written consent to publication and send them to the editorial office before submitting your response [Patient consent forms] ...
http://vetrecordcasereports.bmj.com/content/5/4/e000429.responses
Paroxysmal non-kinesigenic dyskinesia characterised by dystonia in a crossbred dog | Veterinary Record Case Reports
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http://vetrecordcasereports.bmj.com/content/5/4/e000429.alerts
Chorea as a clinical feature of the basophilic inclusion body disease subtype of fused-in-sarcoma-associated frontotemporal...Chorea as a clinical feature of the basophilic inclusion body disease subtype of fused-in-sarcoma-associated frontotemporal...
Choreoathetoid involuntary movements are rarely reported in patients with frontotemporal lobar degeneration (FTLD), suggesting their exclusion as a supportive feature in clinical diagnostic criteria for FTLD. Here, we identified three cases of the behavioral variant of frontotemporal dementia (bvFTD) that display chorea with fused in sarcoma (FUS)-positive inclusions (FTLD-FUS) and the basophilic inclusion body disease (BIBD) subtype. We determined the behavioral and cognitive features in this group that were distinct from other FTLD-FUS cases. We also reviewed the clinical records of 72 FTLD cases, and clarified additional clinical features that are predictive of the BIBD pathology. Symptom onset in the three patients with chorea was at 44.0 years of age (±12.0 years), and occurred in the absence of a family history of dementia. The cases were consistent with a clinical form of FTD known as bvFTD, as well as reduced neurological muscle tone in addition to chorea. The three patients showed no or mild
https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-016-0304-9
Prevalence of anti-basal ganglia antibodies in adult obsessive-compulsive disorder: cross-sectional study. - Department of...
BACKGROUND: Symptoms of obsessive-compulsive disorder (OCD) have been described in neuropsychiatric syndromes associated with streptococcal infections. It is proposed that antibodies raised against streptococcal proteins cross-react with neuronal proteins (antigens) in the brain, particularly in the basal ganglia, which is a brain region implicated in OCD pathogenesis. AIMS: To test the hypothesis that post-streptococcal autoimmunity, directed against neuronal antigens, may contribute to the pathogenesis of OCD in adults. METHOD: Ninety-six participants with OCD were tested for the presence of anti-streptolysin-O titres (ASOT) and the presence of anti-basal ganglia antibodies (ABGA) in a cross-sectional study. The ABGA were tested for with western blots using three recombinant antigens; aldolase C, enolase and pyruvate kinase. The findings were compared with those in a control group of individuals with depression (n = 33) and schizophrenia (n = 17). RESULTS: Positivity for ABGA was observed in 19/96 (19
https://www.psych.ox.ac.uk/publications/355963
Anti-Basal Ganglia Antibody Screening - Private Blood Tests in IrelandAnti-Basal Ganglia Antibody Screening - Private Blood Tests in Ireland
This Private Blood Test for Anti-Basal Ganglia Antibody Screening is available across Ireland through our Nurse home visit service.
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Neurology Podcast Search | American Academy of Neurology®Neurology Podcast Search | American Academy of Neurology®
1) Sydenham chorea and 2) Topic of the month: Historical interviews. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Waugh interviews Dr. Fabienne Brilot-Turville about her paper on antibody binding to neuronal surface in Sydenham chorea. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about fragile X-associated tremor ataxia syndrome. In the next part of the podcast Dr. Farrah Mateen completes our historical interviews for the month by interviewing Dr. Read More 1) Sydenham chorea and 2) Topic of the month: Historical interviews. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Waugh interviews Dr. Fabienne Brilot-Turville about her paper on antibody binding to ...
https://www.aan.com/rss/Search/home/EpisodeDetail?item=2229&segment=1456
HUNTINGTONS CHOREA - Butanoblog | HUNTINGTONS CHOREAHUNTINGTONS CHOREA - Butanoblog | HUNTINGTONS CHOREA
HUNTINGTONS CHOREA is a hereditary disease characterised by choreiform movement and progressive dementia caused by degeneration of
https://butanoblog.com/huntingtons-chorea/
Find Information On How To Live With Huntingtons Chorea | AUSTEDO® (deutetrabenazine) tablets
People with HD chorea may have difficulty with everyday activities. Discover how to assemble your HD chorea care team & learn how to make your home HD chorea friendly.
https://www.austedo.com/huntingtons-chorea/living-with-hd-chorea
Non-ketonic hyperglycemia presenting with acute hemichorea and ballismNon-ketonic hyperglycemia presenting with acute hemichorea and ballism
Non-ketotic hyperglycemia is a complication of poorly controlled diabetes mellitus. Rarely, it can present like an acute neurological syndrome with unilateral choreiform and ballistic movements. Such a presentation usually raises the suspicion of a cerebrovascular event and prompts more workup. Moreover, the neuroimaging in this condition also suggests a variety of potential possibilities. Identification of this rare presentation of non-ketotic hyperglycemia helps with the appropriate management and avoid unnecessary investigations. In this case report, we report the case of an elderly woman who presented with hemichorea-ballism due to non-ketotic hyperglycemia and discuss the literature on this presentation. We also highlighted the differential diagnosis based on neuroimaging ...
https://mospace.umsystem.edu/xmlui/handle/10355/80916
A definition of chorea - HealthyLifeInfo.com Wellness and Health InformationA definition of chorea - HealthyLifeInfo.com Wellness and Health Information
Source: Adapted from the National Institutes of Health. What does the term chorea mean? The term chorea refers to a nervous system disorder characterized by involuntary spasms of the limbs or facial muscles. a hereditary form is called huntingtons chorea. To find out more about this term, please search the news section of this website for related articles and information.. ...
http://www.healthylifeinfo.com/2015/lifehealth/1361/
What are the common causes of chorea | ChoreaWhat are the common causes of chorea | Chorea
Chorea is associated with a number of causes, some temporary and some chronic. Here are some common causes of chorea you should know of.
http://www.onlymyhealth.com/common-causes-chorea-1313051738
A common PRRT2 mutation in familial paroxysmal kinesigenic dyskinesia in Hong Kong: a case series of 16 patients | HKMJA common PRRT2 mutation in familial paroxysmal kinesigenic dyskinesia in Hong Kong: a case series of 16 patients | HKMJ
Patient 1 was a 47-year-old woman who presented with paroxysmal abnormal movement since childhood. She was first seen in 2004. The attack was characterised by dystonic painful posture with upward or downward deviation of the eyes, head turning, shoulder abduction and extensions, lower limb dystonia, impaired speech, and occasionally stepping movements, with preserved consciousness. The attacks lasted for 1 to 2 minutes with a frequency of up to 8 times a day. Each attack was precipitated by stress or being startled, for example, being approached by a car unexpectedly when crossing the road, frightened by a cockroach, a sudden phone call, or an abrupt movement. Occasionally, the attack could occur during sleep. There was no incontinence. The patient had normal intelligence. Physical examination, biochemical tests, computed tomography of the brain, and electroencephalography were normal. The attacks were controlled with carbamazepine and frequency of attacks reduced to fewer than 3 times a day and ...
http://www.hkmj.org/abstracts/v22n6/619.htm
Canine Episodic Movement Disorders | Paroxysmal Dyskinesia | D for DogCanine Episodic Movement Disorders | Paroxysmal Dyskinesia | D for Dog
Paroxysmal dyskinesia is a movement disorder where abnormal movements are seen in dogs during attacks. Often misdiagnosed as canine epilepsy.
https://www.dfordog.co.uk/blog/canine-episodic-movement-disorders.html
Historical walking tour of Marrickville Pumping Station and Sydenham Drainage Pit Tickets, Multiple Dates | EventbriteHistorical walking tour of Marrickville Pumping Station and Sydenham Drainage Pit Tickets, Multiple Dates | Eventbrite
Eventbrite - Marrickville Library and History presents Historical walking tour of Marrickville Pumping Station and Sydenham Drainage Pit - Friday, 18 November 2016 at Sydenham Drainage Pit, Sydenham, NSW. Find event and ticket information.
https://www.eventbrite.com.au/e/historical-walking-tour-of-marrickville-pumping-station-and-sydenham-drainage-pit-tickets-27802453888
Phenotypic insights into ADCY5-associated disease. | Foundation Dystonia ResearchPhenotypic insights into ADCY5-associated disease. | Foundation Dystonia Research
BACKGROUND: Adenylyl cyclase 5 (ADCY5) mutations is associated with heterogenous syndromes: familial dyskinesia and facial myokymia; paroxysmal chorea and dystonia; autosomal-dominant chorea and dystonia; and benign hereditary chorea. We provide detailed clinical data on 7 patients from six new kindreds with mutations in the ADCY5 gene, in order to expand and define the phenotypic spectrum of ADCY5 mutations.
http://foundationdystoniaresearch.org/news/phenotypic-insights-adcy5-associated-disease
Auspex Announces Positive Topline Results From Registration Trial of SD-809 for Chorea Associated With Huntingtons Disease...Auspex Announces Positive Topline Results From Registration Trial of SD-809 for Chorea Associated With Huntingtons Disease...
Based on the data reported today, Auspex expects to file a New Drug Application (NDA) for SD-809 for the treatment of chorea associated with Huntingtons disease by mid-2015.. Auspex also expects to report Phase 1 data for SD-560, a deuterated form of pirfenidone, by mid-2015.. Conference Call Today. Auspex will host a conference call and live audio webcast with slides today at 4:30 PM ET, 1:30 PM PT. To participate in the conference call, please dial 1-844-834-1429 (domestic) or 1-484-653-6711 (international) and refer to conference ID 54690193. A live webcast and slides can be accessed under Events & Presentations in the Investor Relations section of the companys website at www.auspexpharma.com. The archived webcast will be available on the companys website beginning approximately two hours after the event.. About the First-HD Trial. First-HD is a randomized, double-blind, placebo-controlled, parallel-group trial of SD-809 in 90 patients with chorea associated with Huntingtons disease. ...
http://globenewswire.com/news-release/2014/12/16/691862/10112630/en/Auspex-Announces-Positive-Topline-Results-From-Registration-Trial-of-SD-809-for-Chorea-Associated-With-Huntington-s-Disease.html
Sudden onset of chorea - RightDiagnosis.comSudden onset of chorea - RightDiagnosis.com
List of 16 disease causes of Sudden onset of chorea, patient stories, diagnostic guides. Diagnostic checklist, medical tests, doctor questions, and related signs or symptoms for Sudden onset of chorea.
http://www.rightdiagnosis.com/sym/sudden_onset_of_chorea.htm
1 litre of sweat per hour and Choreiform movements and Rapid, synchronous muscle jerking - Symptom Checker - check medical...1 litre of sweat per hour and Choreiform movements and Rapid, synchronous muscle jerking - Symptom Checker - check medical...
List of 61 causes for 1 litre of sweat per hour and Choreiform movements and Rapid, synchronous muscle jerking, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
http://wrongdiagnosis.com/cosymptoms/1-litre-of-sweat-per-hour/choreiform-movements/rapid-synchronous-muscle-jerking.htm
Definition for Huntingtons choreaDefinition for Huntingtons chorea
Huntingtons chorea definition: A hereditary condition of the basal ganglia leading to modern loss in motor coordination.; genetic condition; develops in adulthood and ends in alzhiemers disease
https://www.azdictionary.com/definition/Huntington%27s%20chorea
Huntingtons chorea diagnosis: Costs for treatment #249589 in Germany | BookingHealthHuntingtons chorea diagnosis: Costs for treatment #249589 in Germany | BookingHealth
Huntingtons chorea diagnosis (costs for program #249589) ✔ University Hospital Halle (Saale) ✔ Department of Neurology ✔ BookingHealth.com
https://bookinghealth.com/university-hospital-halle-saale/diagnostic-programs/249589-huntingtons-chorea-diagnosis.html
Huntingtons chorea diagnosis: Costs for treatment #183811 in Germany | BookingHealthHuntingtons chorea diagnosis: Costs for treatment #183811 in Germany | BookingHealth
Huntingtons chorea diagnosis (costs for program #183811) ✔ University Hospital Marburg UKGM ✔ Department of Neuropathology ✔ BookingHealth.com
https://bookinghealth.com/ukgm-marburg/diagnostic-programs/183811-huntingtons-chorea-diagnosis.html
Sydenham Afternoon Weather - AccuWeather Forecast for Eastern Cape South AfricaSydenham Afternoon Weather - AccuWeather Forecast for Eastern Cape South Africa
Get the Sydenham afternoon weather forecast for today, tomorrow and 15 days including the afternoon high temperature, RealFeel and chance of precipitation for Sydenham, South Africa from AccuWeather.com
https://www.accuweather.com/en/za/sydenham/297545/afternoon-weather-forecast/297545?day=6
Student Accommodation in Sydenham - Sydenham Student Housing - RightmoveStudent Accommodation in Sydenham - Sydenham Student Housing - Rightmove
Find a wide range of Student Accommodation in Sydenham. Search for Student Flats, Shared Houses, Halls of Residence and Private Halls close to campus.
http://www.rightmove.co.uk/student-accommodation/Sydenham/3-bed-houses.html
Veränderungen im Proteom von Maus und Mensch durch Huntingtons ChoreaVeränderungen im Proteom von Maus und Mensch durch Huntingtons Chorea
Die Erkrankung Huntington s Chorea ist eine autosomal dominant vererbte Erkrankung, die gewöhnlich im mittleren Lebensabschnitt beginnt und unausweichlich zum Tode führt. In unserem Bestreben, Proteine zu identifizieren, welche an Prozessen Upstream oder Downstream des krankheitsverursachenden Proteins Huntingtin beteiligt sind, wurde das Proteom eines sehr gut etablierten Mausmodells mit Hilfe der Großgel 2D-Elektrophorese untersucht. Es konnte zum ersten Mal auf Proteinebene nachweisen werden, dass die Expression von zwei Serinproteasehemmern, alpha1-Antitrypsin und Contraspin und darüber hinaus eines Chaperons, alphaB-Kristallin, im Verlauf der Erkrankung abnimmt. Reduzierte Expression von alpha1-Antitrypsin und Contraspin konnte in Gehirn, Leber, Herz und Testes nahe dem Endstadium der Erkrankung nachgewiesen werden. Hier ist es wichtig festzustellen, dass die Expressionsabnahme von alpha1-Antitrypsin im Gehirn der Abnahme in der Leber im Herzen und in den Testes vorangeht. Eine ...
https://edoc.hu-berlin.de/handle/18452/15477
danielpvankammen - PLOS Currents Huntington Diseasedanielpvankammen - PLOS Currents Huntington Disease
It is generally believed that treatments are available to manage chorea in Huntingtons disease (HD). However, lack of evidence prevents the establishment of treatment guidelines. The HD chorea research literature fails to address the indications for drug treatment, drug selection, drug dosing and side effect profiles, management of inadequate response to a single drug, and preferred drug when behavioral symptoms comorbid to chorea are present. Because there is lack of an evidence base to inform clinical decision-making, we surveyed an international group of experts to address these points. Survey results showed that patient stigma, physical injury, gait instability, work interference, and disturbed sleep were indications for a drug treatment trial. However, the experts did not agree on first choice of chorea drug, with the majority of experts in Europe favoring an antipsychotic drug (APD), and a near equal split in first choice between an APD and tetrabenazine (TBZ) among experts from North ...
http://currents.plos.org/hd/author/danielpvankammen/
Rheumatic feverRheumatic fever
Condition resulting from an inadequately treated or untreated infection with Group A streptococcus bacteria. It is a delayed immune response in which the body produces antibodies directed against itself (autoimmune). This can cause serious damage to heart valves and lead to symptoms such as swelling and pain in several joints, heart inflammation (carditis), skin nodules, rapid, jerky movements (Sydenhams chorea), and skin rash ...
https://labtestsonline.org/glossary/rheumatic
Treatment | PANDAS NetworkTreatment | PANDAS Network
It has been recommended by physicians that the PANDAS child remain on prophylactic antibiotics in accordance to the RF (Rheumatic Fever) guidelines established by the American Academy of Pediatrics Journal. The RF guideline by the AAP is for 5 years after last attack or until age 21 (whichever is longer). According to the World Health Organization, the duration of prophylaxis for ARF is 5 years after last attack until 18 years old (whichever is longer).. Children who have had Sydenhams Chorea, Rheumatic Fever or PANDAS have a risk of developing a more severe reaction upon reinfection with strep. Prophylaxis prevents reinfection.. Long term prophylactic antibiotic use for PANDAS has been shown in the study Antibiotic Prophylaxis with Azithromycin or Penicillin for Childhood-Onset Neuropsychiatric Disorders to …play a role in the management of children in the PANDAS subgroup, as well as provide support for the assertion that GAS plays an etiologic role in some children with tics and/or ...
https://pandasnetwork.org/treatment/
Plus it
Charles MacKenzie Hendry (Charlie) was a colourful, loveable character who suffered ill health after childhood Sydenhams chorea left him with rheumatic heart disease. He graduated from Edinburgh University in July 1969. After two house jobs at Stracathro Hospital, he joined the practice at 129 Strathmartine Road, Dundee, as general practice trainee. After an obstetrics … ...
http://www.bmj.com/content/334/7584/101.3
Showing results for tags Sydenhams Chorea. - ACN Latitudes ForumsShowing results for tags Sydenhams Chorea. - ACN Latitudes Forums
Here is a very recent article on Sydenhams Chorea. From research, I am learning that children can have relaspes from this until the appropriate treatment is given. Most of the references at the end of this article can be found online for additional reading. My son will be going into the hospital next week and having a central tunneled line. He will also be starting plasma exchange treatments soon afterwards. Our insurance did approve the treatment. I did not realize the damage that strep could do until I started reading articles. My son would never test positive for strep when he was young. After he started taking antibiotics this year, he started testing positive for strep on a rapid strep test. He had the titer test back in December that checked for past strep infections and the levels were high. This finally got my doctors attention because I reminded him that my son would never test positive on rapid strep test. So my question to him was When did my son have these strep infections? I wish ...
https://latitudes.org/forums/tags/Sydenhams%20Chorea/?_nodeSelectName=blog_entry_node&_noJs=1
Huntingtons disease: Genetic heterogeneity in black African patientsHuntingtons disease: Genetic heterogeneity in black African patients
George Huntingtons description of Huntingtons disease (HD) in 1872 (at the age of 22 years) remains the basic pillar of diagnosis: A hereditary chorea, tendency to insanity and suicide and its manifesting itself as a grave disease in adulthood.1 HD is a progressive autosomal dominant disorder, characterised by involuntary choreiform movements, psychiatric manifestations with cognitive decline and, rarely, a bradykinetic rigidity. A G8 HD probe developed in Boston for preclinical and prenatal screening of HD using molecular genetics was first acquired in South Africa in the late 1980s.2 The disease has been shown to be due to an increased number of trinucleotide repeats in the IT 15 gene on chromosome 4p 16.3. Measurement of the CAG trinucleotide expansion has been found to be a highly sensitive and specific marker for the diagnosis of HD (sensitivity 98.8%; 95% confidence interval (CI) 97.7 - 99.4%; specificity 100%, 95% CI 95.2 - 100%).3 In view of the excellent sensitivity and specificity, ...
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742008000300020&lng=pt&nrm=iso&tlng=en
J13 Prescription usage for treatment of irritability, perseverative behaviors, and chorea in huntingtons disease | Journal of...J13 Prescription usage for treatment of irritability, perseverative behaviors, and chorea in huntingtons disease | Journal of...
Results For irritability, SSRI was first choice of 58%, an antipsychotic was first choice for 22%, a mood stabilizing anticonvulsant 14%, and benzodiazepine 2%. For perseverative behaviors, SSRI was first choice of 75%, an antipsychotic choice of 4%, a mood stabilizing anticonvulsant choice of 6%, and clomipramine 2%. The remaining 13% chose to qualify the response to include 2 first choices. For chorea, an antipsychotic was first choice for 56%, tetrabenazine 15%, amantadine 6%, and benzodiazepines 4%. The remaining 13% chose to qualify the response to include 2 first choices. Drug choice for use as adjunctive therapy was widely variable. ...
http://jnnp.bmj.com/content/81/Suppl_1/A43.2
Chorea and Cimetidine | Annals of Internal Medicine | American College of PhysiciansChorea and Cimetidine | Annals of Internal Medicine | American College of Physicians
To the editor: Increasingly frequent reports have attributed neurologic complications other than encephalopathy to cimetidine toxicity. I wish to report a case of chorea apparently caused by cimetidine.. A 72-year-old woman was admitted to the Neurological Institute of New York after several weeks of abnormal movements. The history showed chronic obstructive pulmonic disease treated with theophylline, 800 mg daily, and terbutaline, 15 mg daily in divided doses. Haloperidol had been prescribed for an affective disorder, but symptoms had resolved and therapy had been terminated 18 months earlier. Barium swallow had shown a duodenal ulcer 11 months previously; therapy included cimetidine, ...
https://annals.org/aim/article-abstract/695295/chorea-cimetidine
Safety and Efficacy of Bone Marrow Derived MNCs for Treatment of Cells for the Treatment of Hunting Tons Chorea. - Full Text...Safety and Efficacy of Bone Marrow Derived MNCs for Treatment of Cells for the Treatment of Hunting Tons Chorea. - Full Text...
This study is Single arm, Single Centre trial to check the Safety and Efficacy of Bone Marrow Derived Autologous mononuclear cell {MNC} (100 Million per dose).trial to be conducted for 36 months in patients with diabetes Mellitus in India,Primary outcome measure are Improvement in cognitive and Psychiatric Symptoms and Improvement in Jerky,random, and Uncontrollable Movements called Chorea ...
https://clinicaltrials.gov/ct2/show/NCT01834053?term=Chorea&rank=7
Chorea and Heart failure and Muscle pain and Vision distortion - Symptom Checker - check medical symptoms at RightDiagnosisChorea and Heart failure and Muscle pain and Vision distortion - Symptom Checker - check medical symptoms at RightDiagnosis
List of causes of Chorea and Heart failure and Muscle pain and Vision distortion, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
https://symptoms.rightdiagnosis.com/cosymptoms/chorea/heart-failure/muscle-pain/vision-distortion.htm
Antibodies to AChR, synapse-organizing proteins, titin, and other muscle proteins in Morvans fibrillary chorea<...
TY - JOUR. T1 - Antibodies to AChR, synapse-organizing proteins, titin, and other muscle proteins in Morvans fibrillary chorea. AU - Agius, Mark A.. AU - Zhu, Shan. AU - Lee, Eun Kyu. AU - Aarli, Johan A.. AU - Kirvan, Christine. AU - Fairclough, Robert H. AU - Maselli, Ricardo A. PY - 1998. Y1 - 1998. UR - http://www.scopus.com/inward/record.url?scp=0031879434&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0031879434&partnerID=8YFLogxK. U2 - 10.1111/j.1749-6632.1998.tb10973.x. DO - 10.1111/j.1749-6632.1998.tb10973.x. M3 - Article. C2 - 9668285. AN - SCOPUS:0031879434. VL - 841. SP - 522. EP - 524. JO - Annals of the New York Academy of Sciences. JF - Annals of the New York Academy of Sciences. SN - 0077-8923. ER - ...
https://ucdavis.pure.elsevier.com/en/publications/antibodies-to-achr-synapse-organizing-proteins-titin-and-other-mu
A Care Partners Guide for HD Chorea | AUSTEDO® (deutetrabenazine) tablets
Learn about steps you can take to make looking after yourself a daily priority. The first step when caring for someone with HD chorea is caring for yourself. Find additional resources where you can connect with fellow caregivers online.
https://www.austedo.com/huntingtons-chorea/care-partner-support
Most recent papers with the keyword paroxysmal movement disorders | Read by QxMDMost recent papers with the keyword paroxysmal movement disorders | Read by QxMD
BACKGROUND: Paroxysmal kinesigenic dyskinesia (PKD) is a rare movement disorder characterized by recurrent dystonic or choreoathetoid attacks triggered by sudden voluntary movements. Under the condition of psychological burden, some patients attacks may get worsened with longer duration and higher frequency. This study aimed to assess nonmotor symptoms and quality of life of patients with PKD in a large population. METHODS: We performed a cross-sectional survey in 165 primary PKD patients from August 2008 to October 2016 in Rui Jin Hospital, using Symptom Check List-90-Revised (SCL-90-R), World Health Organization Quality of Life-100 (WHOQoL-100), Self-Rating Depression Scale, and Self-Rating Anxiety Scale ...
https://www.readbyqxmd.com/keyword/104479
Intravenous Immunoglobulins as Effective Treatment in Sydenham's Chorea - Full Text View - ClinicalTrials.govIntravenous Immunoglobulins as Effective Treatment in Sydenham's Chorea - Full Text View - ClinicalTrials.gov
Children are at risk of developing an involuntary movement disorder after streptococcal throat infections. Not all children are affected and the severity is individually variable. Affected children have alteration in their behaviour and mood and can become quite compromised in their activities of daily living. The condition is believed to be related to the body having an over efficient immune response to the infection and some of the antibodies made in response to the infection also attack centres in the brain controlling movement and mood. Treating these children with immunoglobulins, which mop up the antibodies may reverse or improve affected children. This study hopes to clarify this ...
https://clinicaltrials.gov/ct2/show/NCT00615797?cond=%22Choreatic+Disorders%22+OR+%22McLeod+neuroacanthocytosis+syndrome%22+OR+%22Neuroacanthocytosis%22+OR+%22Chorea+Acanthocytosis+Syndromes%22&rank=5
Pnkd (untagged) - Mouse paroxysmal nonkinesiogenic dyskinesia (Pnkd), nuclear gene encoding mitochondrial protein, transcript...
Pnkd (untagged) - Mouse paroxysmal nonkinesiogenic dyskinesia (Pnkd), nuclear gene encoding mitochondrial protein, transcript variant 2, (10ug), 10 µg.
https://www.acris-antibodies.com/cdna/mouse-cdna/pnkd-untagged-mouse-paroxysmal-nonkinesiogenic-dyskinesia-pnkd-nuclear-gene-encoding-mitochondrial-protein-transcript-variant-2-10ug-mc210084.htm
Chronic progressive chorea | definition of chronic progressive chorea by Medical dictionaryChronic progressive chorea | definition of chronic progressive chorea by Medical dictionary
Looking for online definition of chronic progressive chorea in the Medical Dictionary? chronic progressive chorea explanation free. What is chronic progressive chorea? Meaning of chronic progressive chorea medical term. What does chronic progressive chorea mean?
http://medical-dictionary.thefreedictionary.com/chronic+progressive+chorea
Paroxysmal dystonic choreoathetosis linked to chromosome 2q: Clinical analysis and proposed pathophysiology | NeurologyParoxysmal dystonic choreoathetosis linked to chromosome 2q: Clinical analysis and proposed pathophysiology | Neurology
We describe clinical features of a large Polish-American kindred in which autosomal-dominant, paroxysmal dystonic choreoathetosis (PDC) was linked to a locus on chromosome 2q. Episodes of generalized dystonia and choreoathetosis involving the face and all extremities began in early childhood, lasted for 30 minutes to several hours, and occurred up to several times each week. There was no interruption of consciousness and EEGs were normal during the episodes. Paroxysmal dyskinesia occurred at rest both spontaneously and following caffeine or alcohol consumption. Neurologic examinations were normal between attacks. The cause of PDC is unknown. We deduced a model of PDC pathophysiology from analyzing neurophysiologic effects of alcohol and caffeine (which provoke attacks of PDC), the variably beneficial effects of levodopa-carbidopa, and the occurrence of dystonia and paroxysmal dyskinesia in biopterin synthesis disorders. We propose that nigrostriatal neurons in PDC patients have either marginally ...
https://n.neurology.org/content/49/1/177?ijkey=4e06f9ee04eea9d0fc776a8a5760c39749fbc116&keytype2=tf_ipsecsha
Familial dystonic choreoathetosis with myokymia; a sleep responsive disorder. | Journal of Neurology, Neurosurgery & PsychiatryFamilial dystonic choreoathetosis with myokymia; a sleep responsive disorder. | Journal of Neurology, Neurosurgery & Psychiatry
A family is presented with paroxysmal dystonic choreoathetosis transmitted as a dominant trait over five generations. The family is unusual in the marked responsiveness of the episodes to short periods of sleep in several members, in the very variable age of onset, and in the association with prominent myokymia in some cases. These overlap features suggest a link between paroxysmal dystonic choreoathetosis and familial paroxysmal ataxia with myokymia.. ...
http://jnnp.bmj.com/content/54/12/1090
Upper Sydenham | definition of Upper Sydenham by Medical dictionaryUpper Sydenham | definition of Upper Sydenham by Medical dictionary
Looking for online definition of Upper Sydenham in the Medical Dictionary? Upper Sydenham explanation free. What is Upper Sydenham? Meaning of Upper Sydenham medical term. What does Upper Sydenham mean?
https://medical-dictionary.thefreedictionary.com/Upper+Sydenham
Incidence of anti-brain antibodies in children with obsessive-compulsive disorder | The British Journal of PsychiatryIncidence of anti-brain antibodies in children with obsessive-compulsive disorder | The British Journal of Psychiatry
We report here that 42% of patients with obsessive-compulsive disorder (a consecutive cohort of children and adolescents attending a specialist clinic) had circulating anti-basal antibodies. This is a highly significant finding, as these antibodies are uncommonly found in the control groups studied. In contrast, patients with the neurological disorder most robustly established as a post-streptococcal autoimmune disorder - Sydenhams chorea - almost always test positive for these antibodies using the same assays (Church et al, 2002). These findings demonstrate that a subgroup of people with obsessive-compulsive disorder have antibody findings similar to those seen in Sydenhams chorea, suggesting that autoimmunity many have a role in the genesis and/or maintenance of the former disorder. Only a few other studies have looked for anti-neuronal antibodies in obsessive-compulsive disorder. An indirect immunofluorescence method has been used in one small study of idiopathic disease, and did ...
http://bjp.rcpsych.org/content/187/4/314
Familial dyskinesia with facial myokymia (ADCY5 gene) - Breda Genetics srlFamilial dyskinesia with facial myokymia (ADCY5 gene) - Breda Genetics srl
Recommended panel testing at Breda Genetics for this condition (EXOME PANEL):. Familial dyskinesia/chorea panel (ADYC5, NKX2-1, PRRT2, PNKD, SLC2A1). References:. ADCY5-Related Dyskinesia. Shaw C, Hisama F, Friedman J, Bird TD. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018. 2014 Dec 18 [updated 2015 Dec 17]. PMID: 25521004. ADCY5-related dyskinesia: Broader spectrum and genotype-phenotype correlations. Chen DH, Méneret A, Friedman JR, Korvatska O, Gad A, Bonkowski ES, Stessman HA, Doummar D, Mignot C, Anheim M, Bernes S, Davis MY, Damon-Perrière N, Degos B, Grabli D, Gras D, Hisama FM, Mackenzie KM, Swanson PD, Tranchant C, Vidailhet M, Winesett S, Trouillard O, Amendola LM, Dorschner MO, Weiss M, Eichler EE, Torkamani A, Roze E, Bird TD, Raskind WH. Neurology. 2015 Dec 8;85(23):2026-35. PMID: 26537056. ADCY5 mutations are another cause of benign hereditary chorea. ...
https://bredagenetics.com/familial-dyskinesia-with-facial-myokymia-adcy5-gene/
Convulsions, Familial Infantile, with Paroxysmal Choreoathetosis disease: Malacards - Research Articles, Drugs, Genes, Clinical...Convulsions, Familial Infantile, with Paroxysmal Choreoathetosis disease: Malacards - Research Articles, Drugs, Genes, Clinical...
NIH Rare Diseases : 50 the following summary is from orphanet, a european reference portal for information on rare diseases and orphan drugs.orpha number: 31709disease definitioninfantile convulsions and paroxysmal choreoathetosis (icca) syndrome is a neurological condition characterized by the occurrence of seizures during the first year of life (benign familial infantile epilepsy ; see this term) and choreoathetotic dyskinetic attacks during childhood or adolescence.epidemiologythis disorder is rare but the exact prevalence is unknown.clinical descriptionbenign familial infantile epilepsy begins at 3 to 12 months of age with a family history of the same type of seizures. seizures are afebrile, partial or sometimes generalized, and normally disappear after the first year of life. during childhood or adolescence, affected individuals present with paroxysmal kinesigenic dyskinesia with frequent and recurrent episodic choreathetotic or dystonic movements that last less than 1 minute. the attacks ...
http://www.malacards.org/card/convulsions_familial_infantile_with_paroxysmal_choreoathetosis?search=glaucoma
New Drug Is Effective in Treating HD ChoreaNew Drug Is Effective in Treating HD Chorea
A phase 3 clinical trial of tetrabenazine showed the drug to be effective in the treatment of chorea associated with Huntingtons disease (HD). The results of the study presented at the 129th annual meeting of the American Neurological Association validated the treatment success that has been seen in Europe, Australia, and Canada. In a randomized, double-blind, placebo-controlled study of 84 patients with HD, patients received either tetrabenazine or a placebo for 12 weeks. The objective was to change baseline scores on the Unified Huntingtons Disease Rating Scale, which is used to assess clinical elements. After 12 weeks, the chorea score for the tetrabenazine group had decreased by 5 points, whereas the scores for the placebo group had decreased by only 1.5 points. Tetrabenazine also was proven to be superior to placebo on the Clinical Global Impression Scale, which assesses severity of illness and change in clinical condition. The drugs manufacturer, Prestwick Pharmaceuticals Inc, plans to ...
http://www.pharmacytimes.com/publications/issue/2004/2004-12/2004-12-4828
Homeopathy Treatment For Chorea | RC HomeopathyHomeopathy Treatment For Chorea | RC Homeopathy
Homeopathy Serves As A Good Supportive Treatment And Helps Manage The Symptoms Of Chorea. As The Symptoms Of Chorea Vary Depending Upon The Underlying Condition.
https://www.rchomeopathy.com.au/treatment-of-chorea-in-homeopathy/
Hemichorea--a late sequel of an extradural haematoma. | Postgraduate Medical JournalHemichorea--a late sequel of an extradural haematoma. | Postgraduate Medical Journal
Hemichorea developed several weeks after evacuation of a traumatic extradural haematoma. The abnormal movements were confined to arm and leg on the side opposite the surgery. No other causes of chorea were found. The connection between the extradural haematoma and the late onset hemichorea is not well understood; mechanical pressure on basal ganglia structures, vascular disturbances of the anterior choroidal artery as well as biochemical alterations are all possible mechanisms.. ...
http://pmj.bmj.com/content/59/693/462
christne, Author at
From the very beginning its important to understand that all three disorders involve abnormal involuntary non-stereotypical movement. The difference consists in the muscles affected, speed and style.. Chorea involves rapid, non-stereotypical,jerky, involuntary, repetitive, dance-like movements. The moves involve the distal muscle group more than the proximal.. Unlike chorea, athetosis is a slow non-stereotypical, repetitive, involuntary, writing movement that usually affects the upper limbs.. Ballismus is also a rapid non-stereotypical, involuntary, repetitive and relatively more violent move that affects the proximal muscle group more than the distal.. Many times athetosis and chorea occur together and that is called choreoathetosis.. The involuntary movements might merge into semipurposeful or purposeful acts that could mask them.. Chorea is a progressive neurological disorder that is caused most often by Huntingtons disease. Rheumatic fever can also cause what is called the Sydenhams ...
http://lets-jam.com/author/christne/
Most recent papers with the keyword Drug induced paroxysmal movement disorders | Read by QxMDMost recent papers with the keyword Drug induced paroxysmal movement disorders | Read by QxMD
The literature on paediatric acute-onset movement disorders is scattered. In a prospective cohort of 52 children (21 male; age range 2mo-15y), the commonest were chorea, dystonia, tremor, myoclonus, and Parkinsonism in descending order of frequency. In this series of mainly previously well children with cryptogenic acute movement disorders, three groups were recognised: (1) Psychogenic disorders (n = 12), typically ,10 years of age, more likely to be female and to have tremor and myoclonus (2) Inflammatory or autoimmune disorders (n = 22), including N-methyl-d-aspartate receptor encephalitis, opsoclonus-myoclonus, Sydenham chorea, systemic lupus erythematosus, acute necrotizing encephalopathy (which may be autosomal dominant), and other encephalitides and (3) Non-inflammatory disorders (n = 18), including drug-induced movement disorder, post-pump chorea, metabolic, e ...
https://www.readbyqxmd.com/keyword/104480
Choreoathetosis - TheWetLab
Choreoathetosis is a condition where the brain does not produce enough cerebrospinal fluid (CSF) to keep the body healthy. The condition occurs when there are problems with the production or absorption of CSF by one or both sides of the brain. This may occur due to various diseases such as:. A blockage in a blood vessel leading from the heart, which prevents it from pumping enough blood through your head and neck area.. A blockage in a vein supplying the brain, causing it to become starved for oxygen.. An infection of the lining of the brain (encephalitis).. The most common cause of choreoathetosis is cerebral palsy (CP), but other conditions can lead to its development. The condition affects approximately 1 in every 100 children under five years old.. It is estimated that up to 30% of children with CP will develop choreoathetosis.. Symptoms of choreoathetosis include:. Difficulty breathing (paroxysm) or difficulty swallowing (peristalsis).. Headache.. Other symptoms may include: dizziness, ...
http://wetlab.org/choreoathetosis-2/
Anti-basal ganglia antibodies are absent in patients with primary blepharospasm | NeurologyAnti-basal ganglia antibodies are absent in patients with primary blepharospasm | Neurology
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.. Google Safari Microsoft Edge Firefox. Click here to login. ...
https://n.neurology.org/content/58/1/150.1.full
Multimedia Archives - The Western Journal of Emergency Medicine
Paul J. Myers, DO, et al. Sydenham Chorea (SC) is an acute rheumatic fever complication. SC is the most common acquired childhood chorea, usually affecting children five to fifteen years of age.1 It occurs following an untreated group A streptococcal infection and a latent period of one to six months.1,2 Despite rheumatic fever diminishing, 18% to 36% of acute rheumatic fever patients develop SC.3 Full recovery often takes several months; some patients suffer permanent neurologic sequelae.1. An 11-year old male presented to the Emergency Department with two days of uncontrolled body twitching. The movements affected his right arm and leg, with occasional lip twitches; he experienced intermittent confusion and hyperactivity. The patient denied recent illness, but recalled a fever with headache and vomiting several months prior. Besides the above findings, his physical examination was normal.. ...
https://westjem.com/tag/multimedia
Evaluation of the epidemiological findings of acute rheumatic fever between 1981 and 2012 - - ScopeMed.org - Deposit for...Evaluation of the epidemiological findings of acute rheumatic fever between 1981 and 2012 - - ScopeMed.org - Deposit for...
Between 1981-1990, 1991-2000, 2001-2012; 573, 1677, 1688 patients had been followed up, respectively. In these three periods of follow up time carditis was observed in (51, 62 and 71% of patients), arthritis in (67, 68, 56% of patients), Sydenhams chorea in (13, 13 and 13% of patients) and erythema marginatum in (2, 0.1, 1% of patients), respectively. Between 1981-1990, 1991-2000 and 2001-2012 the incidence of ARF was detected 1.1/100.000, 2.6/100.000 and 2.3/100.000, respectively ...
http://www.scopemed.org/?mno=1002251
The not choreic neurological complications of rheumatic disease (authors transl)]. - Semantic ScholarThe not choreic neurological complications of rheumatic disease (authors transl)]. - Semantic Scholar
The authors discuss the importance of neurological complications of rheumatic disease, which differ from those of Sydenhams chorea: encephalitis; acute cerebral circulatory insufficiency of cardiovascular basis; thrombosis and cerebral haemorrhage; cerebral emboli; and vasculitis. The case of a 13 year old boy who presented with an acute cerebral episode during an active phase of rheumatic fever is described. The E.E.G. showed a right hemisphere disturbance with a slight involvement of the controlateral hemisphere. The cardiac evidence was indicative of a rheumatic carditis. The clinical progress and EEG were rapidly favourable. The possible pathogenetic hypotheses of this case are taken into consideration, and the authors suggest that one must suspect a rheumatic etiology when an acute cerebral syndrome is established in a child or a young adult with current or previous rheumatic fever.
https://www.semanticscholar.org/paper/The-not-choreic-neurological-complications-of-rhe-Terzano-Manzoni/b7ca9775c92cccb73654e95d1b153170d7e21f73
Gross hematuria - Medical DictionaryGross hematuria - Medical Dictionary
Group A strep A well-known strain (a type) of streptococcus (strep) bacteria that can cause strep throat and common skin problems such as impetigo as well as rheumatic fever. Autoimmune reactions to strep have also recently been associated with a number of disorders, including guttate psoriasis (cradle cap), Sydenhams chorea (a movement disorder related to rheumatic fever), obsessive-compulsive […]. ...
https://definithing.com/define-medical/gross-hematuria/
The OCD Strep-Connection - OCD Resource CenterThe OCD Strep-Connection - OCD Resource Center
Western Suffolk Psychological Services, Inc., Huntington, New York. Over the last ten years, there has appeared a mounting body of evidence that suggests there is a small subgroup of individuals whose childhood onset Obsessive-Compulsive Disorders may have been triggered by streptococcal throat infections. This association of an infectious cause with a neurobiological disorder may also be true for tic disorders, such as Tourettes Disorder, Trichotillomania (compulsive hair pulling), and possibly Attention Deficit Hyperactivity Disorder.. These conclusions were drawn from research conducted by Drs. Susan Swedo, Judith Rappaport, and their associates at The National Institute of Mental Health. During the late 1980s, they observed that children with Sydenhams Chorea, the neurobiological manifestation that follows bouts of Rheumatic Fever, had an unusually high percentage of OCD symptoms, including both obsessions and compulsions. Rheumatic Fever is caused by Group A Beta hemolytic streptococcal ...
http://www.ocdhope.com/2014/03/the-ocd-strep-connection/
Non-ketotic hyperglycaemia hemichorea-hemiballismus and acute ischaemic stroke -- Carrion and Carrion 2013 -- BMJ Case ReportsNon-ketotic hyperglycaemia hemichorea-hemiballismus and acute ischaemic stroke -- Carrion and Carrion 2013 -- BMJ Case Reports
Here we describe a patient with a rare movement disorder, hemichorea-hemiballismus, which is described as a complication of non-ketotic hyperglycaemia. This complication may be seen in individuals with poorly controlled long-standing diabetes mellitus. Proper diagnosis is established with CT and MRI of the brain, which typically show classic findings in the basal ganglia. Treatment focuses on improvement of glycaemic control and usually results in rapid resolution of the movement disorder. Nevertheless, recurrent episodes of hemichorea-hemiballismus, and even more ominous complications such as ischaemic stroke may occur. ...
http://casereports.bmj.com/content/2013/bcr-2012-008359.abstract
Chorea or Basal Ganglia Dysfunction ~ Caring for ColeChorea or Basal Ganglia Dysfunction ~ Caring for Cole
My grandpa who just passed away suffered from St. Vitis Dance as a child. I believe it is the same as chorea or a form of it. I have never understood it much. It went away and reoccurred just about 2 years ago. That just one of many of the factors in his end. In the end he couldnt swallow at all. I never understood the disease much. I am glad to see you have a medical knowledge of it. Hang in there Leanne. It is possible for him to maintain the tremors and there are things that can be done. My grandpa overcame it as a child when very little was known about it at all and lived a long healthy life until the end when it reoccured. I hope all the rest of your family is doing well.. ReplyDelete ...
http://caringforcole.blogspot.com/2008/09/chorea-or-basal-ganglia-dysfunction.html
FDA Advisory Committee Votes Unanimously to Recommend Approval of Tetrabenazine for Chorea Associated With Huntingt... ( ...FDA Advisory Committee Votes Unanimously to Recommend Approval of Tetrabenazine for Chorea Associated With Huntingt... ( ...
Health,... WASHINGTON Dec. 6 /- An advisory committee to the U.... The advisory committees support of tetrabenazine represents animpor...While the FDA is not required to follow the advice of its advisorycom...HD is a devastating neurodegenerative disease that causes progressive...,FDA,Advisory,Committee,Votes,Unanimously,to,Recommend,Approval,of,Tetrabenazine,for,Chorea,Associated,With,Huntington,Disease,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
http://www.bio-medicine.org/medicine-news-1/FDA-Advisory-Committee-Votes-Unanimously-to-Recommend-Approval-of-Tetrabenazine-for-Chorea-Associated-With-Huntington-Disease-7800-1/
Page Numbers and Dates - AMA Manual of StylePage Numbers and Dates - AMA Manual of Style
Do not omit digits from inclusive page numbers. The year, followed by a semicolon; the volume number and the issue number (in parentheses), followed by a colon; the initial page number, a hyphen, and the final page number, followed by a period, are set without spaces. 1. Rainier S, Thomas D, Tokarz D, et al. Myofibrillogenesis regulator 1 gene mutations cause paroxysmal dystonic choreoathetosis. Arch Neurol. 2004;61(7):1025-1029. 2. Hyduk A, Croft JB, Ayala C, Zheng K, Zheng Z-J, Mensah GA. Pulmonary hypertension surveillance United States, 1980 2002. MMWR Surveill Summ. 2005;54(5):1-28. |
http://www.amamanualofstyle.com/view/10.1093/jama/9780195176339.001.0001/med-9780195176339-div2-44?rskey=tpOCa8&result=10&q=
Top Chinese Massage Therapists in Sydenham VIC | NaturalTherapyPages.com.auTop Chinese Massage Therapists in Sydenham VIC | NaturalTherapyPages.com.au
Need Chinese Massage Therapists near your area? Check out NaturalTherapyPages.com.aus list of the best Traditional Chinese Massage in Sydenham VIC.
https://www.naturaltherapypages.com.au/massage/vic/sydenham/chinese_massage
Sydenham Place, Tenby Street North, Jewellery Quarter Birmingham.Sydenham Place, Tenby Street North, Jewellery Quarter Birmingham.
Sydenham Place is 14,508 sq. ft. of development which consists of 6 apartments in the stunning Grade II Listed Building & 3 new build Town Houses built in Jewellery Quarter.
https://jameslaurenceuk.com/sydenham-place-tenby-street-north-birmingham/
Acute rheumatic fever with chorea | Archives of Disease in ChildhoodAcute rheumatic fever with chorea | Archives of Disease in Childhood
A 9-year-old girl was admitted for the recent onset of jerky, uncoordinated choreiform uncontrollable body movements that disappeared while sleeping, clumsiness (see supplementary video 1), slurred speech and episodes of uncontrollable crying.She had a history of mild sore throat 4 weeks before, followed after about 10 days by a non-pruritic, painless, erythematosus macular rash at legs gluteus … ...
http://adc.bmj.com/content/98/3/203.short?rss=1
spinocerebellar ataxia - The Neurology Loungespinocerebellar ataxia - The Neurology Lounge
Neurologists are familiar with tetrabenazine, the best treatment for chorea. And Star Trek fans are familiar with the heavy hydrogen atom, deuterium. Put the two together and, voila, you get deutetrabenazine (SD809). The heavy hydrogen of deuterium makes deutetrabenazine a more stable drug. This should make it last longer in the body, and also cause less side effects. Considering that the adverse effects of tetrabenazine include depression and parkinsonism, this is not an insignificant advantage (pardon the double negative…I couldnt help it).. How well does deutetrabenazine translate to clinical practice? Sufficiently well enough it seems, going by the trial published in JAMA Neurology titled Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease. The authors compared the drug to placebo and showed that deutetrabenazine effectively improved chorea at 12 weeks. It is not surprising that the trial compared deutetrabenazine to placebo rather than the existing alternative; ...
https://theneurologylounge.com/tag/spinocerebellar-ataxia/
Little Salmon Lake Trail | Ontario Trails CouncilLittle Salmon Lake Trail | Ontario Trails Council
Trails wind through rugged terrain to Moulton Gorge, the Arkon Lake Bog, the Black Lake homestead and the Crab Lake mines. From Otter Lake, hikers and canoeists head into the interior for glimpses of osprey and kingfisher, deer and black bear, coyote and fox, and abundant beaver. Wilderness skills courses are offered in summer and winter.. Go north on Sydenham Road (Frontenac County Road 9) for approximately 20 km. At the end of the road you will see a Provincial Park sign (Blue and white), telling you to turn left on County Road 5.. As you enter the village of Sydenham, watch for another Park sign on your right (1.9 km). From then on follow the signs. You will go though Sydenham crossing a small bridge over the Millhaven creek and passing a grocery and a beer store on your right as you leave the village. After driving 13 Km on curvy County Road 19, you will see a larger Park sign indicating a right turn and a drive of 2.4 km. This is the Salmon Lake road (just after the Outfitter), it ends at ...
https://www.ontariotrails.on.ca/trails/view/frontenac-provincial-park---little-salmon-lake-trail
Evidence for the existence of homolateral and contralateral projections from the substantia nigra to the subthalamic nucleus in...
TY - GEN. T1 - Evidence for the existence of homolateral and contralateral projections from the substantia nigra to the subthalamic nucleus in the rat. AU - Lakke, E.A.J.F.. AU - Heida, Tjitske. AU - Usunoff, K.G.. AU - Marani, Enrico. PY - 2005/5/14. Y1 - 2005/5/14. N2 - Hemichorea/ballism is a rare neurological disorder but the crucial involvement of the subthalamic nucleus (STN) in its pathophysiology is appreciated since decades. The idiopathic Parkinsons disease is a common neurodegenerative disorder but the key role of the STN in the pathophysiological origin of the parkinsonian state became only recently evident. The STN was believed to exert an inhibitory, probably - GABA-mediated, effect on its projection nuclei, and this belief is one of the major reasons to overlook the involvement of the STN in the parkinsonian pathophysiology. It is now firmly established that the STN projection neurons are glutamatergic, excitatory, and heavily innervate by widely branching axons of the substantia ...
https://research.utwente.nl/en/publications/evidence-for-the-existence-of-homolateral-and-contralateral-proje
Parkinsonism/dystonia syndrome secondary to multiple sclerosis with antibasal Ganglia antibodies<...
TY - JOUR. T1 - Parkinsonism/dystonia syndrome secondary to multiple sclerosis with antibasal Ganglia antibodies. AU - Delgado, Silvia. AU - Baez, Sheila. AU - Singer, Carlos. AU - Sengun, Cenk. AU - Sheremata, William A.. AU - Papapetropoulos, Spiridon. PY - 2009/1/30. Y1 - 2009/1/30. UR - http://www.scopus.com/inward/record.url?scp=61649127335&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=61649127335&partnerID=8YFLogxK. U2 - 10.1002/mds.22331. DO - 10.1002/mds.22331. M3 - Article. C2 - 18951536. AN - SCOPUS:61649127335. VL - 24. SP - 309. EP - 311. JO - Movement Disorders. JF - Movement Disorders. SN - 0885-3185. IS - 2. ER - ...
https://miami.pure.elsevier.com/en/publications/parkinsonismdystonia-syndrome-secondary-to-multiple-sclerosis-wit
Tetrabenazine by Sterimax - Uses, Side Effects, Interactions - Canada.com
Tetrabenazine by Sterimax: Tetrabenazine belongs to the class of medications called monoamine depleting agents. It is used to reduce uncontrolled movement that is seen in Huntingtons chorea, tardive dyskinesia, hemiballismus, senile chorea, tic and Tourettes syndrome. This medication works in the brain, interfering with the storage of some of the chemicals that are linked to movement disorders, such as serotonin and dopamine.
https://bodyandhealth.canada.com/drug/getdrug/tetrabenazine-by-sterimax
Lirias: Can the Dyskinesia Impairment Scale be used by inexperienced raters? A reliability studyLirias: Can the Dyskinesia Impairment Scale be used by inexperienced raters? A reliability study
BACKGROUND: The Dyskinesia Impairment Scale (DIS) is a new scale for measuring dystonia and choreoathetosis in dyskinetic Cerebral Palsy (CP). Previously, reliability of this scale has only been assessed for raters highly experienced in discriminating between dystonia and choreoathetosis. AIMS: The aims of this study are to examine the reliability of the DIS used by inexperienced raters, new to discriminating between dystonia and choreoathetosis and to determine the effect of clinical expertise on reliability. METHODS: Twenty-five patients (17 males; 8 females; age range 5-22 years; mean age = 13 years 6 months; SD = 5 years 4 months) with dyskinetic CP were filmed with the DIS standard video protocol. Two junior physiotherapists (PTs) and three senior PTs, all of whom were new to discriminating between dystonia and choreoathetosis, were trained in scoring the DIS. Afterward, they independently scored all patients from the video recordings using the DIS. Reliability was assessed by (1) ...
https://lirias.kuleuven.be/handle/123456789/373807
Effects of Cannabidiol in Huntingtons DiseaseEffects of Cannabidiol in Huntingtons Disease
EFFECTS OF CANNABIDIOL IN HUNTINGTONS DISEASE Neurology 36 (Suppl 1) April 1986 p. 342 Reuven Sandyk, Paul Consroe, Lawrence Z. Stern, and Stuart R. Snider, Tucson, AZ. Cannabidiol (CBD) is a major nonpsychoactive cannabinoid of marijuana. Based on reports indicating possible efficacy of CBD in dystonic movements (Neurology 1984; 34 [Suppl 1]: 147 and 1985; 35 [Suppl 1]: 201), we tried CBD in three patients with Huntingtons disease (HD). The patients;, aged 30 to 56, had HD of 7 to 12 years duration. Their condition has been slowly progressive and unresponsive to prior therapy with neuroleptics. Orally administered CBD was initiated at 300 mg/d and increased 1 week later to 600 mg/d for the next 3 weeks. Mild improvement ( 5 to 15%) in the choreic movements was documented using the tongueprotrusion test (Neurology [Minneap} 1972; 22: 929-33) and a chorea severity evaluation scale (Br J Clin Pharmacol 1981; 11: 129-51) after the first week. Further improvement (20 to 40%) was noticed after the ...
http://www.druglibrary.org/schaffer/hemp/medical/hunting1.htm
Dystonia/Chorea worse at night - BrainTalk CommunitiesDystonia/Chorea worse at night - BrainTalk Communities
Dystonia is a neurological disorder that causes the muscles to contract and spasm involuntarily. There are approximately 13 forms of dystonia, and dozens of diseases and conditions include dystonia as a major symptom. Dystonia may affect a single body area or be generalized throughout multiple muscle groups. Dystonia is a chronic disorder, but the vast majority of dystonias do not impact cognition, intelligence, or shorten a persons life span.
https://www.braintalkcommunities.org/forum/neurological-disorders-and-injury/dystonia/6781-dystonia-chorea-worse-at-night?view=media
Teva Receives Complete Response Letter for NDA for SD-809 for the Treatment of Chorea Associated with Huntington Disease |...Teva Receives Complete Response Letter for NDA for SD-809 for the Treatment of Chorea Associated with Huntington Disease |...
Teva Pharmaceutical Industries Ltd. (NYSE and TASE:TEVA) today announced that it has received a Complete Response Letter (CRL) from the U.S. Food and
https://www.businesswire.com/news/home/20160531005496/en/Teva-Receives-Complete-Response-Letter-NDA-SD-809
Dystonia/Chorea worse at nightDystonia/Chorea worse at night
Hi- I am old to this forum (spent a lot of time here in 1999 on for my son with ADHD/Autism) but new to dystonia. I believe my dystonia is due to dysautonomia so it is paroxysmal making it much harder for me to figure out triggers. Currently my only treatment is propranolol which also controls my tachycardia from the dystautonomia and when it is really back percocet because it is the only thing that calms my body and controls the pain. When the dystonia is bad it aggravate my fibromyalgia,
http://braintalkcommunities.org/showthread.php/101068-Dystonia-Chorea-worse-at-night?s=22b24c9b1fd2d6bf57db6b335455f6f8&p=52168
4.9.3 Drugs used in essential tremor, chorea, tics, and related disorders
Bladder wall botulinum toxin injection for use in adults with urinary incontinence due to detrusor overactivity is approved for use in Devon, when used in accordance with the relevant NICE clinical guideline (see Commissioning Policy for more details ...
https://northeast.devonformularyguidance.nhs.uk/formulary/chapters/4.-central-nervous-system/4-9-drugs-used-in-parkinsonism-and-related-disorders/4-9-3-drugs-used-in-essential-tremor-chorea-tics
Benign Familial and Non-Familial Infantile Seizures | Epilepsy FoundationBenign Familial and Non-Familial Infantile Seizures | Epilepsy Foundation
Although diurnal focal seizures occur during benign familial and non-familial infantile seizures, they typically dont progress to generalized convulsions. Read more at the Epilepsy Foundation today.
https://www.epilepsy.com/living-epilepsy/epilepsy-and/professional-health-care-providers/about-epilepsy-seizures/idiopathic-epileptic-seizures-and-syndromes-infancy/benign-familial-and-non-familial-infantile-seizures-watanabe
Genes | Free Full-Text | Mitochondrial PCK2 Missense Variant in Shetland Sheepdogs with Paroxysmal Exercise-Induced Dyskinesia ...Genes | Free Full-Text | Mitochondrial PCK2 Missense Variant in Shetland Sheepdogs with Paroxysmal Exercise-Induced Dyskinesia ...
Four female Shetland Sheepdogs with hypertonic paroxysmal dyskinesia, mainly triggered by exercise and stress, were investigated in a retrospective multi-center investigation aiming to characterize the clinical phenotype and its underlying molecular etiology. Three dogs were closely related and their pedigree suggested autosomal dominant inheritance. Laboratory diagnostic findings included mild lactic acidosis and lactaturia, mild intermittent serum creatine kinase (CK) elevation and hypoglycemia. Electrophysiological tests and magnetic resonance imaging of the brain were unremarkable. A muscle/nerve biopsy revealed a mild type II fiber predominant muscle atrophy. While treatment with phenobarbital, diazepam or levetiracetam did not alter the clinical course, treatment with a gluten-free, home-made fresh meat diet in three dogs or a tryptophan-rich, gluten-free, seafood-based diet, stress-reduction, and acetazolamide or zonisamide in the fourth dog correlated with a partial reduction in, or even a
https://www.mdpi.com/2073-4425/11/7/774
Meeting lengths staying short as planners cut costs - ICCA Resource ICCAMeeting lengths staying short as planners cut costs - ICCA Resource ICCA
ICCA, the International Congress and Convention Association is the global meetings industry network. ICCA can assist meeting organisers in finding the main specialists in handling, transporting, and accommodating international events. ICCA offers a variety of benefits for suppliers, such as networking, education, and promotion, as well as business opportunities through databases containing valuable information on congress organisers and details on international meetings. - ICCA - ICCA
http://dev.iccaworld.org/nlps/story.cfm?nlpage=479
The NH2 Terminus of RCK1 Domain Regulates Ca2+-dependent BKCa Channel Gating | JGPThe NH2 Terminus of RCK1 Domain Regulates Ca2+-dependent BKCa Channel Gating | JGP
BKCa channels, encoded by the Slo1 gene (Atkinson et al., 1991; Adelman et al., 1992; Butler et al., 1993; Tseng-Crank et al., 1994), are dually activated by voltage and cytosolic Ca2+, allowing outward K+ current to repolarize the membrane and prevent further entry of Ca2+ ions into the cell through voltage-dependent Ca2+ channels (Marty, 1981; Pallotta et al., 1981; Hudspeth and Lewis, 1988b; Robitaille et al., 1993; Cui et al., 1997; Yazejian et al., 1997). They play key regulatory roles in diverse physiological functions involving cellular [Ca2+]i, such as neurotransmitter release (Robitaille et al., 1993; Yazejian et al., 1997), cochlear hair-cell tuning (Hudspeth and Lewis, 1988a,b; Fettiplace and Fuchs, 1999; Duncan and Fuchs, 2003), arterial smooth muscle tone regulation (Nelson et al., 1995; Brenner et al., 2000), and immunity (Ahluwalia et al., 2004). Recently, it was found that a mutation in the BKCa α-subunit is linked to generalized epilepsy and paroxysmal dyskinesia by altering ...
http://jgp.rupress.org/content/126/3/227
Sydenham Veterinary Services | Care GuidesSydenham Veterinary Services | Care Guides
When a dogs teeth are not properly cleaned or cared for on a regular basis, plaque and tarter can build up on the tooth surface and underneath the gumline. This material can irritate the gums, causing inflammation known as gingivitis. If left untreated, gingivitis can lead to the development of periodontitis, which is the infection and inflammation of structures that support the teeth. Periodontal disease tends to include both gingivitis and periodontitis.. Read More ...
http://sydvets.vetstreet.com/care_guide.html?p=38&type=Canine
Huntingtons DiseaseHuntingtons Disease
Huntingtons Disease, sometimes known as Huntingtons Chorea due to the characteristic involuntary movement of head and limbs, is a progressive neurological disease. It was made famous in several ways. Woody Guthrie, the legendary folk singer, died of HD. HD has dominant inheritance, and is ultimately fatal. HD sufferers experience uncontrolled movements as the neurons involved with various body functions die. Typically, physical decay happens first, followed by mental decay and ultimately a vegetative state. HD was among the first human disease that was located by positional cloning on the human genome using modern marker technology (see references below). It was sequenced in 1993, confirming that the malady involved a trinucleotide repeat. Despite all the research on this tragic disease, there is no cure and very few medications to alleviate symptoms. ...
http://www.stat.wisc.edu/~yandell/ewing/hd.html
Knowledge Module - ICCAKnowledge Module - ICCA
ICCA, the International Congress and Convention Association is the global meetings industry network. ICCA can assist meeting organisers in finding the main specialists in handling, transporting, and accommodating international events. ICCA offers a variety of benefits for suppliers, such as networking, education, and promotion, as well as business opportunities through databases containing valuable information on congress organisers and details on international meetings. - ICCA - ICCA
https://dev.iccaworld.org/knowledge/
Huntingtons Disease: A Caregivers Guide - Caregiver.comHuntingtons Disease: A Caregivers Guide - Caregiver.com
Those afflicted with what is sometimes also called Huntingtons chorea eventually cant walk or communicate the way they once did.
https://caregiver.com/articles/huntingtons-caregiver-guide/
George HuntingtonGeorge Huntington
On Chorea. Huntington, George. On Chorea. "Dr. George Huntington and the Disease Bearing His Name". web.archive.org. 2006-07-18 ... During this period, he was able to better observe the cases of hereditary chorea, which he had seen for the first time with his ... On February 15, 1872 George Huntington gave his classic presentation on chorea to the Meigs and Mason Academy of Medicine in ... Wikisource has original text related to this article: On Chorea Wikiquote has quotations related to William Osler, including ...
https://en.wikipedia.org/wiki/George_Huntington
NeuroacanthocytosisNeuroacanthocytosis
Chorea acanthocytosis is characterised by dystonia, chorea and progressive cognitive, behavioural changes and seizures. ... Chorea acanthocytosis is an autosomal recessive disorder caused by mutations in the VPS13A, also called CHAC, on chromosome ... "Chorea In Children." EMedicine - Medical Reference (2008). 23 September 2008. 8 February 2010. Rampoldi L, Danek A, Monaco AP ( ... There are about 500-1,000 cases of chorea acanthocytosis worldwide and it is not specific to any particular ethnic group. ...
https://en.wikipedia.org/wiki/Neuroacanthocytosis
List of hematologic conditionsList of hematologic conditions
"Chorea-acanthocytosis". Genetic Home Reference. U.S. National Library of Medicine, National Institutes of Health. May 2008. ...
https://en.wikipedia.org/wiki/List_of_hematologic_conditions
The Dancing Mania, an epidemic of the Middle AgesThe Dancing Mania, an epidemic of the Middle Ages
For example, Thomas Sydenham explored chorea in the 17th century, in which his description of symptoms of what he named chorea ... Sydenham's chorea was often incorrectly referred to as St. Vitus' dance. The research that had previously been done was limited ... "Sydenham Chorea , National Institute of Neurological Disorders and Stroke". www.ninds.nih.gov. Retrieved 2022-07-25. "Die ... Brabazon, A. B. (1880). "Chorea Sancti Viti, Or St. Vitus's Dance: Its Treatment With The Bath Mineral Waters". The British ...
https://en.wikipedia.org/wiki/The_Dancing_Mania,_an_epidemic_of_the_Middle_Ages
Tardive dyskinesiaTardive dyskinesia
Huntington's chorea). Deutetrabenazine, an isotopic isomer of tetrabenazine, was approved by the FDA for tardive dyskinesia in ...
https://en.wikipedia.org/wiki/Tardive_dyskinesia
TicTic
Dystonias, paroxysmal dyskinesias, chorea, other genetic conditions, and secondary causes of tics should be ruled out in the ... Tics must be distinguished from movements of disorders such as chorea, dystonia and myoclonus; the compulsions of obsessive- ... Sydenham's chorea; idiopathic dystonia; and genetic conditions such as Huntington's disease, neuroacanthocytosis, pantothenate ...
https://en.wikipedia.org/wiki/Tic
TourettismTourettism
Chorea (disease) Myoclonus Dystonia Torsion dystonia Idiopathic dystonia Chromosomal abnormalities Citrullinemia Down syndrome ... Sydenham's chorea; idiopathic dystonia; and genetic conditions such as Huntington's disease, neuroacanthocytosis, pantothenate ... Schizophrenia Tuberous sclerosis Wilson's disease XYY syndrome Encephalitis Mycoplasma pneumoniae Sydenham's chorea Pervasive ...
https://en.wikipedia.org/wiki/Tourettism
1872 in science1872 in science
Lanska, D. J. (2000). "George Huntington (1850-1916) and hereditary chorea". Journal of the History of the Neurosciences. 9 (1 ... ISBN 978-1-84724-008-8. Huntington, G. (1872-04-13). "On Chorea". Medical and Surgical Reporter of Philadelphia. 26 (15): 317- ... Vale, Thiago Cardoso; Cardoso, Francisco (2015). "Chorea: A journey through history". Tremor and Other Hyperkinetic Movements. ...
https://en.wikipedia.org/wiki/1872_in_science
Substance-induced psychosisSubstance-induced psychosis
Azar S, Ramjiani A, Van Gerpen JA (April 2005). "Ciprofloxacin-induced chorea". Mov. Disord. 20 (4): 513-4, author reply 514. ... myoclonus and chorea like), visual hallucination in two elderly patients]. Nippon Ronen Igakkai Zasshi (in Japanese). 36 (3): ... Myoclonus and Chorea Like), Visual Hallucination in Two Elderly Patients" [Levofloxacin-induced neurological adverse effects ...
https://en.wikipedia.org/wiki/Substance-induced_psychosis
Bed restBed rest
"Sydenham Chorea Information Page , National Institute of Neurological Disorders and Stroke". ninds.nih.gov. Retrieved 30 ... Bed rest may be sufficient treatment for mild cases of Sydenham chorea. In those with deep vein thrombosis early movement ...
https://en.wikipedia.org/wiki/Bed_rest
List of OMIM disorder codesList of OMIM disorder codes
CSMF Chorea, hereditary benign; 118700; NKX2-1 Choreoacanthocytosis; 200150; VPS13A Choreoathetosis, hypothyroidism, and ...
https://en.wikipedia.org/wiki/List_of_OMIM_disorder_codes
Thordar QuelprudThordar Quelprud
Ørbeck, Alf L; Quelprud, Thordar (1954). Setesdalsrykka (Chorea progressiva hereditaria). Oslo: Jacob Dybwad. (Articles with ...
https://en.wikipedia.org/wiki/Thordar_Quelprud
AthetosisAthetosis
Chorea is another condition which results from damage to the basal ganglia. Similar to athetosis, it results from mutations ... Considering the etiology of both disorders are fairly similar, it comes as no surprise that chorea and athetosis can and ... Chorea Dyskinesia Dystonia Pupillary athetosis Walker, Kenneth H (1990). "Ch. 70 Involuntary Movements". Clinical Methods: The ... Bhidayasiri, R; Truong, DD (September 2004). "Chorea and related disorders". Postgraduate Medical Journal. 80 (947): 527-34. ...
https://en.wikipedia.org/wiki/Athetosis
Depth AffectDepth Affect
In 2010 the group made the EP Chorea. Songs from the EP can be downloaded free from SoundCloud. In 2010 and 2011 the group ... ". "Critique de l'EP Chorea". Richard, Philippe. "Depth Affect : 'Draft Battle' disponible". Archived from the original on ...
https://en.wikipedia.org/wiki/Depth_Affect
Violet CriesViolet Cries
... the video appears to deal with the concept of Chorea as in the film the cast imitate the effects of Chorea. The band then ... Later on they released the third and final single off the album, "Chorea", was released for Record Store Day. A short film was ... "Esben and the Witch - Chorea". Matadorrecs. Retrieved 19 May 2013. "East Coast USA March 2011". Esben and the Witch Facebook. ... "Chorea" - 4:25 "Warpath" - 4:28 "Battlecry/Mimicry" - 1:20 "Eumenides" - 6:12 "Swans" - 4:36 Bonus disc "Lucia, at the ...
https://en.wikipedia.org/wiki/Violet_Cries
Dancing maniaDancing mania
Vitus' Dance was diagnosed, in the 17th century, as Sydenham chorea. Dancing mania has also been known as epidemic chorea: 125 ... A disease of the nervous system, chorea is characterized by symptoms resembling those of dancing mania,: 134 which has also ... Giménez-Roldán S, Aubert G (June 2007). "Hysterical chorea: Report of an outbreak and movie documentation by Arthur Van ... ISBN 978-1-4191-5424-9. "NINDS Sydenham Chorea Information Page". NINDS. USA: NIH. Retrieved 4 September 2010. Schullian, DM ( ...
https://en.wikipedia.org/wiki/Dancing_mania
Bradshaw LectureBradshaw Lecture
"The Bradshaw Lecture ON CHOREA". The Lancet. 196 (5074): 1081-1086. 1920. doi:10.1016/S0140-6736(01)19959-9. "Bradshaw Lecture ... Chorea 1918 William Aldren Turner, Neuroses and psychoses of war 1917 Ernest Septimus Reynolds, Causes of Disease 1916 Hector ...
https://en.wikipedia.org/wiki/Bradshaw_Lecture
Henry HeadHenry Head
Brain, 1905, 28, 116-338.) A case of Huntington's chorea. (Brain, 1905, 28, 98.) A case of Huntington's chorea. (Brain, 1905, ...
https://en.wikipedia.org/wiki/Henry_Head
NirvanolNirvanol
It is useful in the treatment of chorea. Metabolism of nirvanol is stereoselective, with the (S)- enantiomer undergoing roughly ... Ashby HT (February 1930). "Treatment of Chorea by Nirvanol". Archives of Disease in Childhood. 5 (25): 42-3. doi:10.1136/adc. ...
https://en.wikipedia.org/wiki/Nirvanol
List of deprecated terms for diseasesList of deprecated terms for diseases
"NINDS Sydenham Chorea Information Page". February 14, 2007. Archived from the original on July 22, 2010. Retrieved May 8, 2012 ...
https://en.wikipedia.org/wiki/List_of_deprecated_terms_for_diseases
Grandiose delusionsGrandiose delusions
McHugh, P.R; Folstein, M.F (1975). "Psychiatric syndromes in Huntington's chorea". Psychiatric Aspectes of Neurological Disease ...
https://en.wikipedia.org/wiki/Grandiose_delusions
Thomas SydenhamThomas Sydenham
Among other things Sydenham is credited with the first diagnosis of scarlatina and with the modern definition, of chorea (in ... Kushner HI, Cortes D.: Sydenham's chorea. In: Koehler PJ, Bruyn GW, Pearce JMS, eds. Neurological Eponyms. Oxford - New York, ... Pearce, J.M.S. (1995). "Thomas Sydenham and Richard Bright on chorea". J. Neurol. Neurosurg. Psychiatry. 58 (3): 319. doi: ... Sydenham's chorea, also known as St Vitus' Dance. To him is attributed the prescient dictum, "A man is as old as his arteries ...
https://en.wikipedia.org/wiki/Thomas_Sydenham
Hormone replacement therapyHormone replacement therapy
Suchowersky O, Muthipeedika J (December 2005). "A case of late-onset chorea". Nat Clin Pract Neurol. 1 (2): 113-6. doi:10.1038/ ... Severe depression Unusual bleeding Loss of appetite Skin rash Lassitude Fever Dark-colored urine Light colored stool Chorea The ...
https://en.wikipedia.org/wiki/Hormone_replacement_therapy
Oswaldo Frota-PessoaOswaldo Frota-Pessoa
Risks of manifestation of Huntington chorea. J. Génét. Humaine, vol. 26, pp. 33-35. Mosalve, M.V., Erdmann, B., Otto, P.A. and ...
https://en.wikipedia.org/wiki/Oswaldo_Frota-Pessoa
Glossary of psychiatryGlossary of psychiatry
Chorea refers to erratic involuntary movements. The term comes from the Greek word "choreia" or "dance" since usually large ...
https://en.wikipedia.org/wiki/Glossary_of_psychiatry
Dancing plague of 1518Dancing plague of 1518
Diverse choreas (St. Vitus' dance, St. John's dance, and tarantism) were labeled in the Middle Ages referring to the ... Sydenham's chorea Tanganyika laughter epidemic Viegas, Jennifer (1 August 2008). "'Dancing Plague' and Other Odd Afflictions ... This psychogenic illness could have created a chorea (from the Greek khoreia meaning "to dance"), a situation comprising random ... Cardoso, Francisco; Seppi, Klaus; Mair, Katherina J; Wenning, Gregor K; Poewe, Werner (July 2006). "Seminar on choreas". The ...
https://en.wikipedia.org/wiki/Dancing_plague_of_1518
PANDASPANDAS
The cause is thought to be akin to that of Sydenham's chorea (SC), which is known to result from childhood group A ... The symptoms should not be better explained by another disorder, such as Syndenham chorea or Tourette syndrome. The authors ... Bonthius D, Karacay B (2003). "Sydenham's chorea: not gone and not forgotten". Semin Pediatr Neurol. 10 (1): 11-9. doi:10.1016/ ...
https://en.wikipedia.org/wiki/PANDAS
Basal ganglia diseaseBasal ganglia disease
"Sydenham Chorea Information Page" Archived 2010-07-22 at the Wayback Machine Saint Vitus Dance, Rheumatic Encephalitis from the ... Sydenham's chorea is a disorder characterized by rapid, uncoordinated jerking movements primarily affecting the face, hands and ... Archived April 18, 2008, at the Wayback Machine Swedo SE, Leonard HL, Shapiro MB (1993). "Sydenham's Chorea:Physical and ... Janavs JL, Aminoff MJ (October 1998). "Dystonia and chorea in acquired systemic disorders". J. Neurol. Neurosurg. Psychiatry. ...
https://en.wikipedia.org/wiki/Basal_ganglia_disease
DystoniaDystonia
Janavs, J. L; Aminoff, M. J (1998). "Dystonia and chorea in acquired systemic disorders". Journal of Neurology, Neurosurgery & ... Medicine portal Extrapyramidal symptoms Hypertonia Sydenham's chorea Ulegyria (brain condition with dystonia symptoms) " ...
https://en.wikipedia.org/wiki/Dystonia
Claud MuirheadClaud Muirhead
"On chorea in its relation to rheumatism". University of Edinburgh Research Archive. hdl:1842/31809. Retrieved 6 August 2020.{{ ...
https://en.wikipedia.org/wiki/Claud_Muirhead
Chorea-acanthocytosis: MedlinePlus GeneticsChorea-acanthocytosis: MedlinePlus Genetics
Chorea-acanthocytosis is primarily a neurological disorder that affects movement in many parts of the body. Explore symptoms, ... Chorea-acanthocytosis is primarily a neurological disorder that affects movement in many parts of the body. Chorea refers to ... In addition to chorea, another common feature of chorea-acanthocytosis is involuntary tensing of various muscles (dystonia), ... Nearly half of all people with chorea-acanthocytosis have seizures.. Individuals with chorea-acanthocytosis may develop ...
https://medlineplus.gov/genetics/condition/chorea-acanthocytosis/
Sydenham chorea: MedlinePlus Medical EncyclopediaSydenham chorea: MedlinePlus Medical Encyclopedia
Sydenham chorea is a movement disorder that occurs after infection with specific bacteria called group A streptococcus. ... Vitus dance; Chorea minor; Rheumatic chorea; Rheumatic fever - Sydenham chorea; Strep throat - Sydenham chorea; Streptococcal ... Sydenham chorea is a major sign of acute RF. The person may currently or recently have had the disease. Sydenham chorea may be ... Sydenham chorea usually clears up in a few months. In rare cases, an unusual form of Sydenham chorea may begin later in life. ...
https://medlineplus.gov/ency/article/001358.htm
Tardive Dyskinesia Drug Safe, Effective for Huntingtons ChoreaTardive Dyskinesia Drug Safe, Effective for Huntington's Chorea
Valbenazine is effective in improving symptoms of chorea for patients with Huntingtons disease, without any increase in ... "We know that not all chorea warrants treatment, but when chorea is problematic, it should be addressed," lead investigator Erin ... "Based on our work and others, we feel that there is an unmet medical need for the symptomatic treatment of chorea in HD," Furr ... FDA Okays Once-Daily Tardive Dyskinesia, Huntington Chorea Drug * Can Speech Analysis Identify Premanifest and Early-Stage ...
http://www.medscape.com/viewarticle/972355
Chorea in Behçets syndromeChorea in Behçet's syndrome
Chorea in Behçets syndrome J Neurol. 1982;227(2):89-92. doi: 10.1007/BF00313774. ...
https://pubmed.ncbi.nlm.nih.gov/6180143/?dopt=Abstract
Chorea and Tick-Borne Encephalitis, Poland - Volume 19, Number 9-September 2013 - Emerging Infectious Diseases journal - CDC
Nonhereditary causes of chorea, such as infectious chorea in the course of acute manifestations of bacterial or aseptic ... Hagiwara K, Tominaga K, Okada Y, Kido M, Yamasaki R, Shida N, Post-streptococcal chorea in an adult with bilateral striatal ... West Nile virus (WNV) infection presenting as acute chorea. Travel Med Infect Dis. 2012;10:52-3. DOIPubMedGoogle Scholar ... Chorea arises deep in the basal ganglia; high-definition MRI demonstrates caudate atrophy (7). In patients with TBE, MRI may ...
https://wwwnc.cdc.gov/eid/article/19/9/13-0804
Chorea Homeopathic Treatment | Chorea Homeopathic Treatment Guide
Understanding homeoapthy treatment for Chroea and the indicated homeopathic remedies for Chorea. Dr. Manish Bhatia. ... A Case of Chorea Managed with Classical Homeopathy A Case of Chorea Major Chorea Following an MMR Vaccination (Measles, Mumps, ... Chorea can occur with other movement disorders in certain neurological syndromes.. Causes of chorea are multifold and include ... Conventional treatment for Chorea There is no effective treatment is available for chorea in conventional medicine. There are ...
https://hpathy.com/cause-symptoms-treatment/chorea/
Sydenham chorea Information | Mount Sinai - New YorkSydenham chorea Information | Mount Sinai - New York
... recovery and follow-up care for Sydenham chorea. ... Learn about Sydenham chorea, find a doctor, complications, ... Sydenham chorea. St. Vitus dance; Chorea minor; Rheumatic chorea; Rheumatic fever - Sydenham chorea; Strep throat - Sydenham ... Sydenham chorea is a major sign of acute RF. The person may currently or recently have had the disease. Sydenham chorea may be ... Sydenham chorea usually clears up in a few months. In rare cases, an unusual form of Sydenham chorea may begin later in life. ...
https://www.mountsinai.org/health-library/diseases-conditions/sydenham-chorea
An exploration of the genetics of the mutant Huntingtin (mHtt) gene in a cohort of patients with chorea from different tribes...An exploration of the genetics of the mutant Huntingtin (mHtt) gene in a cohort of patients with chorea from different tribes...
An exploration of the genetics of the mutant Huntingtin (mHtt) gene in a cohort of patients with chorea from different tribes ... An exploration of the genetics of the mutant Huntingtin (mHtt) gene in a cohort of patients with chorea from different tribes ... An exploration of the genetics of the mutant Huntingtin (mHtt) gene in a cohort of patients with chorea from different tribes ... An exploration of the genetics of the mutant Huntingtin (mHtt) gene in a cohort of patients with chorea from different tribes ...
https://www.medrxiv.org/node/539862.external-links.html
Neurocrine Biosciences Announces Positive Phase 3 Data for KINECT-HD Study Evaluating Valbenazine for Chorea Associated with...Neurocrine Biosciences Announces Positive Phase 3 Data for KINECT-HD Study Evaluating Valbenazine for Chorea Associated with...
Total Maximal Chorea (TMC) Score Placebo-Adjusted Mean Reduction in TMC Score of 3.2 Units in Valbenazine-Treated Patients ... Neurocrine Biosciences Announces Positive Phase 3 Data for KINECT-HD Study Evaluating Valbenazine for Chorea Associated with ... Huntingtons Disease Highly Statistically Significant Reduction in Chorea Movements (p , 0.0001) as Measured by the Unified ... Neurocrine Biosciences Announces Positive Phase 3 Data for KINECT-HD Study Evaluating Valbenazine for Chorea Associated with ...
https://hdsa.org/news/neurocrine-biosciences-announces-positive-phase-3-data-for-kinect-hd-study-evaluating-valbenazine-for-chorea-associated-with-huntington-disease/
Regional distribution of choline acetyltransferase in the human brain: changes in Huntingtons chorea. | Journal of Neurology,...Regional distribution of choline acetyltransferase in the human brain: changes in Huntington's chorea. | Journal of Neurology,...
Regional distribution of choline acetyltransferase in the human brain: changes in Huntingtons chorea. ... Regional distribution of choline acetyltransferase in the human brain: changes in Huntingtons chorea. ... Regional distribution of choline acetyltransferase in the human brain: changes in Huntingtons chorea. ...
https://jnnp.bmj.com/content/38/7/669.share
Investigation of neuropsychiatric aspects of Sydenhams Chorea: case series review - Enlighten: ThesesInvestigation of neuropsychiatric aspects of Sydenham's Chorea: case series review - Enlighten: Theses
Hypthesis: There is an association with the severity of chorea symptoms in Sydenhams chorea and psychiatric diagnosis. Primary ... The psychiatric diagnoses were not correlated with whether the child had chorea at the time of the study or not. Conclusions: ... During and after the chorea developed all children developed new or more severe psychiatric symptoms and there was an overall ... Punukollu, Mallika (2017) Investigation of neuropsychiatric aspects of Sydenhams Chorea: case series review. MSc(R) thesis, ...
https://theses.gla.ac.uk/9071/
Teva Announces FDA Acceptance of Resubmitted New Drug Application for SD-809 for Treatment of Chorea Associated with Huntington...
Teva Announces FDA Acceptance of Resubmitted New Drug Application for SD-809 for Treatment of Chorea Associated with Huntington ... SD-809 is being developed for the treatment of chorea associated with Huntington disease, a neurodegenerative movement disorder ... HD is the most common genetic cause of abnormal involuntary writhing movements called chorea. ... for the treatment of chorea associated with Huntington disease (HD). The FDA has assigned a Prescription Drug User Fee Act ( ...
https://www.tevapharm.com/news-and-media/latest-news/teva-announces-fda-acceptance-of-resubmitted-new-drug-application-for-sd-809-for-treatment-of-chorea-asso/
Teva Announces FDA Acceptance of Resubmitted New Drug Application for SD-809 for Treatment of Chorea Associated with Huntington...
Teva Announces FDA Acceptance of Resubmitted New Drug Application for SD-809 for Treatment of Chorea Associated with Huntington ... SD-809 is being developed for the treatment of chorea associated with Huntington disease, a neurodegenerative movement disorder ... HD is the most common genetic cause of abnormal involuntary writhing movements called chorea. ... for the treatment of chorea associated with Huntington disease (HD). The FDA has assigned a Prescription Drug User Fee Act ( ...
https://www.tevausa.com/news-and-media/press-releases/teva-announces-fda-acceptance-of-resubmitted-new-drug-application-for-sd-809-for-treatment-of-chorea-asso/
Non-Clinical Physician Jobs, Careers, and Opportunities: First Drug for Huntington's Disease Chorea Approved by the FDA
Xenazine (tetrabenazine) is the first agent approved by the FDA for chorea in Huntingtons Disease (HD). A highly selective and ...
https://www.nonclinicaljobs.com/2008/08/first-drug-for-huntingtons-disease.html
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis | Acta Neuropathologica Communications | Full TextTherapeutic targeting of Lyn kinase to treat chorea-acanthocytosis | Acta Neuropathologica Communications | Full Text
Chorea-Acanthocytosis (ChAc) is a devastating, little understood, and currently untreatable neurodegenerative disease caused by ... Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis. Access & Citations. * 2267 Article Accesses. ...
https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-021-01181-y/metrics
Neurocrine Closer To Ingrezza Label Expansion With Huntingtons Chorea Phase III Win :: ScripNeurocrine Closer To Ingrezza Label Expansion With Huntington's Chorea Phase III Win :: Scrip
Neurocrine Closer To Ingrezza Label Expansion With Huntingtons Chorea Phase III Win. * 08 Dec 2021. ... Subject: Neurocrine Closer To Ingrezza Label Expansion With Huntingtons Chorea Phase III Win ...
https://scrip.pharmaintelligence.informa.com/SC145551/Neurocrine-Closer-To-Ingrezza-Label-Expansion-With-Huntingtons-Chorea-Phase-III-Win
Showing results for tags PANS. - ACN Latitudes ForumsShowing results for tags 'PANS'. - ACN Latitudes Forums
Sydenhams chorea along with PANDAS eacampbell67 posted a topic in PANS / PANDAS (Lyme included) ... wondered if anyone has a kid with Sydenhams chorea (SC) diagnosis?? my dd got her SC diagnosis confirmed by Dr. L last week. ...
https://latitudes.org/forums/tags/PANS/
Huntingtons Chorea - IResearchNetHuntington's Chorea - IResearchNet
This disorder was traditionally known as Huntingtons chorea (after the Greek word for dance) because of the involuntary ... Drugs antagonistic to dopamine D2 receptors reduce the chorea of early HD, and some experimental treatments may help to ...
https://psychology.iresearchnet.com/developmental-psychology/health-psychology-development/huntingtons-chorea/
Yn Chorea Twoaie - WikipediaYn Chorea Twoaie - Wikipedia
She çheer syn Aishey ee yn Chorea Twoaie. Tee çhemmit liorish y Chorea Yiass dan jiass, liorish y Çheen dan twoaie as ... Chorea Twoaie, yn · Chorea Yiass, yn · Çhorshey, yn1 · Chyrgistaan, yn · Earack, yn · Eeraan, yn · Egypt, yn3 · h-Ellanyn ... Feddynit ass "https://gv.wikipedia.org/w/index.php?title=Yn_Chorea_Twoaie&oldid=299288" ...
https://gv.wikipedia.org/wiki/Yn_Chorea_Twoaie
A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD) - Full...A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD) - Full...
Chorea. Dyskinesias. Movement Disorders. Heredodegenerative Disorders, Nervous System. Neurodegenerative Diseases. Genetic ... chorea, dystonia, gait, and postural stability. Each item is scored on a scale of 0-4, where 0 is normal, and 4 is the ...
https://clinicaltrials.gov/ct2/show/NCT05107128?term=SAGE-718&draw=2&rank=4
IMSEAR at SEARO: Chorea mollis with carditis.
Chorea mollis with carditis. Journal of the Indian Medical Association. 1977 May; 68(10): 210-2. ...
https://imsear.searo.who.int/handle/123456789/96081?locale=es
Chorea and Tick-Borne Encephalitis, Poland - Volume 19, Number 9-September 2013 - Emerging Infectious Diseases journal - CDC
Nonhereditary causes of chorea, such as infectious chorea in the course of acute manifestations of bacterial or aseptic ... Hagiwara K, Tominaga K, Okada Y, Kido M, Yamasaki R, Shida N, Post-streptococcal chorea in an adult with bilateral striatal ... West Nile virus (WNV) infection presenting as acute chorea. Travel Med Infect Dis. 2012;10:52-3. DOIPubMedGoogle Scholar ... Chorea arises deep in the basal ganglia; high-definition MRI demonstrates caudate atrophy (7). In patients with TBE, MRI may ...
https://wwwnc-origin.cdc.gov/eid/article/19/9/13-0804
Neuropsychological profile of an adult with Chorea-Acanthocytosis: a case studyNeuropsychological profile of an adult with Chorea-Acanthocytosis: a case study
FRISON, Thirzá Baptista et al. Neuropsychological profile of an adult with Chorea-Acanthocytosis: a case study. Cuad. ... Palavras-chave : Chorea-acanthocytosis; Neuroacanthocytosis; cognition; neuropsychological assessment; Theory of Mind; case ...
http://pepsic.bvsalud.org/scielo.php?script=sci_abstract&pid=S0718-41232012000200007&lng=pt&nrm=iso&tlng=en
Chorea | MedLink NeurologyChorea | MedLink Neurology
Chorea describes a syndrome characterized by brief, abrupt involuntary movements resulting from a continuous flow of random ... Secondary chorea.. Immune-mediated chorea. Sydenham chorea (SD) is an autoimmune disease manifested after streptococcal ... This is possible in drug-induced chorea, metabolic or endocrine choreas, and to some extent even in immunologic choreas such as ... Sydenham chorea and variants (chorea gravidarum and contraceptive-induced chorea). • Systemic lupus erythematosus ...
https://www.medlink.com/articles/chorea
About the festival | CHOREA
CHOREA GALA takes place every year at the beginning of summer in a magical outdoors. riverbank venue located in Bratislava at ... CHOREA GALA is highly acclaimed by expert critics and enjoys great interest from the. artistic circles as well as the general ... CHOREA GALA is a unique grandiose showcase of world-class modern ballet held in the. very heart of Europe. ... As a one-of-a-kind festival, CHOREA GALA displays top performers from world renowned. ballet groups in luxurious environment of ...
https://chorea.sk/en/about-the-festival/
Chorea Huntington - Haunting MemoryChorea Huntington - Haunting Memory
... Download links. Chorea Huntington - Haunting Memory. MP3 version 1644 downloads at 34 mb/s ... Chorea Huntington - Haunting Memory listening: where to download for free?. You can currently download the Chorea Huntington - ... Artist: Chorea Huntington. Albums title: Haunting Memory. Label: Terror Tubbies ‎- TTR 22 Type: Cassette, Album, Stereo ... Chorea Huntington - Haunting Memory. FLAC version 1730 downloads at 35 mb/s. ...
https://music.flactopmusic.com/299625-chorea-huntington-haunting-memory.html
Emergency Response Safety and Health Database: Glossary | NIOSH | CDCEmergency Response Safety and Health Database: Glossary | NIOSH | CDC
See also chorea.. Chronic. Marked by long duration, by frequent recurrence over a long time, and often by slow progression to ... Chorea. Any of various nervous disorders of infectious or organic origin marked by spasmodic movements of the limbs and facial ...
https://www.cdc.gov/niosh/ershdb/glossary.html
DIFFERENTIAL DIAGNOSIS OF CHOREA - ABIBLODIFFERENTIAL DIAGNOSIS OF CHOREA - ABIBLO
Differential diagnosis of chorea are : -oral contraceptive. -SLE. -rheumatic fever. -chorea gravidarum -hyperthyroidism - ...
https://www.abiblo.com/abiblo-differential-diagnosis/differential-diagnosis-of-chorea
Tardive Dyskinesia: Overview, Pathophysiology, EtiologyTardive Dyskinesia: Overview, Pathophysiology, Etiology
Some cases of chorea can be classified as akathisia and stereotypy, whereas other cases of chorea can be classified as ... Chorea may persist after the episode has ended. One fifth of patients with Sydenham chorea experience a recurrence, typically ... Sydenham chorea is characterized by the rapid onset of chorea, muscular weakness, hypotonia, dysarthria, obsessions, ... Unlike TD, Huntington disease appears with chorea in the face and the proximal extremities. The term chorea implies a dancelike ...
https://emedicine.medscape.com/article/1151826-overview
Huntington's ChoreaDystoniaSydenhamHereditary choreaSymptomsMovementsTreating Huntington's diseaseRheumaticGravidarumSydenham's ChoreaDyskinesiaTreatment of chorea associatedCarditisParkinsonismHuntingtonSyndromesChoreatic DisordersDevelopment of choreaChoreoathetosisSymptomaticGeneticDisordersMovementNeurologicalGaitHomeopathicDopamineTetrabenazineBallismValbenazineFrightClinicalSevereBehavioralMutationsExtremitiesGreekSeizuresAdultsDiseasesBasalPsychiatric
Huntington's Chorea3
  • Regional distribution of choline acetyltransferase in the human brain: changes in Huntington's chorea. (bmj.com)
  • This disorder was traditionally known as Huntington's chorea (after the Greek word for dance) because of the involuntary movements associated with HD. (iresearchnet.com)
  • A broad range of chronic neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's chorea, stroke (multi-infarct) dementia, amyotrophic lateral sclerosis and AIDS dementia are now believed to be caused, at least in part, by the excitotoxic action of GLU/ASP (1-3, 7-10). (antiaging-nutrition.com)
Dystonia4
  • In addition to chorea, another common feature of chorea-acanthocytosis is involuntary tensing of various muscles (dystonia), such as those in the limbs, face, mouth, tongue, and throat. (medlineplus.gov)
  • Three other forms of hyperkinetic disorders, namely tics, dystonia, and myoclonus have to be differentiated from chorea. (hpathy.com)
  • The motor section of the UHDRS assesses motor features of HD with standardized ratings of oculomotor function, dysarthria, chorea, dystonia, gait, and postural stability. (clinicaltrials.gov)
  • The aim of the treatment is symptomatic and addresses the hyperkinetic disorders (chorea, dystonia, myoclonus, tics, etc.) and the behavioral and cognitive disturbances (depression, anxiety, psychosis, etc.) associated with the disease. (cdc.gov)
Sydenham9
  • Sydenham chorea is a movement disorder that occurs after infection with specific bacteria called group A streptococcus. (medlineplus.gov)
  • Sydenham chorea is caused by an infection with bacteria called group A streptococcus. (medlineplus.gov)
  • Sydenham chorea is a major sign of acute RF. (medlineplus.gov)
  • Sydenham chorea may be the only sign of RF in some people. (medlineplus.gov)
  • Sydenham chorea occurs most often in girls before puberty, but may be seen in boys. (medlineplus.gov)
  • Sydenham chorea usually clears up in a few months. (medlineplus.gov)
  • In rare cases, an unusual form of Sydenham chorea may begin later in life. (medlineplus.gov)
  • Husby described antineuronal antibodies using an immunofluorescent technique in 46% of patients with Sydenham chorea (n = 30) compared with 14% of patients with rheumatic fever (without chorea) (n = 50) and only 1.8-4% of control subjects (n = 203). (medscape.com)
  • The absence of supporting evidence of preceding streptococcal infection should make the diagnosis doubtful, except in Sydenham chorea or low-grade carditis when rheumatic fever is first discovered after a long latent period from the antecedent infection. (cdc.gov)
Hereditary chorea1
  • ADCY5 gene mutation is the second most common cause of benign hereditary chorea. (medlink.com)
Symptoms8
  • The signs and symptoms of chorea-acanthocytosis usually begin in early to mid-adulthood. (medlineplus.gov)
  • The selection of homeopathic medicine of chorea is based upon the theory of individualization and symptoms similarity by using holistic approach. (hpathy.com)
  • Hypthesis: There is an association with the severity of chorea symptoms in Sydenham's chorea and psychiatric diagnosis. (gla.ac.uk)
  • During and after the chorea developed all children developed new or more severe psychiatric symptoms and there was an overall increase in range of psychiatric symptoms experienced. (gla.ac.uk)
  • Conclusions: The study suggests that the majority of children who develop psychiatric problems in the context of a diagnosis of Sydenham's chorea are likely to have pre-morbid vulnerability to psychiatric symptoms. (gla.ac.uk)
  • Cognitive and behavioral symptoms are the first manifestations of Huntington disease, the most common cause of genetic chorea. (medlink.com)
  • Use this guide when you discuss your chorea symptoms with your doctor - whether it's in person or through telemedicine - to help determine if AUSTEDO is right for you. (austedo.com)
  • Dementia and difficulty controlling movements (chorea) are its symptoms. (webmd.com)
Movements14
  • Chorea refers to the involuntary jerking movements made by people with this disorder. (medlineplus.gov)
  • About 90% of these patients experience chorea, which includes involuntary, nonrhythmic movements that appear to flow from one muscle to another. (medscape.com)
  • Intensive propulsion, involuntary muscle movements (limbs and face), muscle weakness of left upper and lower limbs, and "walk dance" in 38-year-old man with tick-borne encephalitis and chorea, Poland. (cdc.gov)
  • When chorea is severe, the movements may cause motion of the arms or legs that results in throwing whatever is in the hand or falling to the ground. (hpathy.com)
  • Homeopathic medicine of chorea indicated when movements characterized by great violence and affecting the parts of body corrosive. (hpathy.com)
  • Chorea complicated with hysteria, movements confined to lower extremities. (hpathy.com)
  • SD-809 is being developed for the treatment of chorea associated with Huntington disease, a neurodegenerative movement disorder that impacts cognition, behavior, and movements. (tevapharm.com)
  • HD is the most common genetic cause of abnormal involuntary writhing movements called chorea. (tevapharm.com)
  • Chorea, derived from the Latin choreus meaning "dance," describes a syndrome characterized by irregular, hyperkinetic, involuntary movements resulting from a continuous flow of random muscle contractions. (medlink.com)
  • Chorea is considered a movement disorder that is characterized by involuntary, irregular, yerky muscular movements. (cannakeys.com)
  • Many people with Huntington disease develop involuntary jerking or twitching movements known as chorea. (medlineplus.gov)
  • She was seen in the clinic on day 12, by which time the chorea had subsided, but she still exhibited some infrequent buccal-oral movements. (ochsnerjournal.org)
  • Nitoman contains Tetrabenazine, a monoamine-depleting agent that may be recommended to treat the involuntary muscle movements (chorea) of Huntington's disease. (northwestpharmacy.com)
  • Chorea (sudden involuntary, uncoordinated jerky movements, e.g. (fpnotebook.com)
Treating Huntington's disease1
  • A drug currently approved for tardive dyskinesia (TD) is also effective at treating Huntington's disease (HD)-associated chorea, a movement disorder that affects most patients with HD, new phase 3 trial results show. (medscape.com)
Rheumatic1
  • A number of different typically chronic conditions can contribute to the development of chorea such as Huntington's disease (a neurological disorder), Sydenham's chorea (associated with a history of rheumatic fever), chorea-acanthocytosis (a genetic disorder), or pharmaceutical drug induced chorea (e.g. levodopa), for example. (cannakeys.com)
Gravidarum1
  • When making the diagnosis of chorea gravidarum (CG), it is important to keep in mind the diagnositc considerations and to maintain a high index of suspicion and vigilance. (medscape.com)
Sydenham's Chorea2
  • Primary Objective: To identify, using a validated, structured diagnostic interview, the prevalence of psychiatric diagnoses before, during, and after the presence of chorea in a regional, clinic-based case series of children and adolescents with a history of Sydenham's chorea. (gla.ac.uk)
  • The pathology of Sydenham's chorea. (medscape.com)
Dyskinesia2
  • Individualize dosage based on symptom control (i.e., reduction of chorea or dyskinesia) and tolerability. (drugs.com)
  • Unlike TD tardive dyskinesia, Huntington disease appears with chorea (derived from the Greek word meaning to dance) in the face and the proximal extremities. (medscape.com)
Treatment of chorea associated2
  • While tetrabenazine and deutetrabenazine have been found to be effective in the treatment of chorea associated with HD, both of these drugs have some limitations, including the need for multiple daily dosing," said Jankovic, who was not involved with the research. (medscape.com)
  • Teva Pharmaceutical Industries Ltd. (NYSE and TASE:TEVA) today announced that the U.S. Food and Drug Administration (FDA) has accepted the resubmission of the New Drug Application (NDA) for SD-809 (deutetrabenazine) for the treatment of chorea associated with Huntington disease (HD). (tevapharm.com)
Carditis2
  • IMSEAR at SEARO: Chorea mollis with carditis. (who.int)
  • Chorea mollis with carditis. (who.int)
Parkinsonism1
  • Neuropathological findings in chorea-acanthocytosis: new insights into mechanisms underlying parkinsonism and seizures. (medlineplus.gov)
Huntington4
  • The 2 conditions are easily distinguishable because juvenile Huntington disease is characterized by rigid-akinetic syndrome, cognitive decline, and occasional seizure disorder, but almost never chorea. (medlink.com)
  • Chorea Huntington - Haunting Memory listening: where to download for free? (flactopmusic.com)
  • You can currently download the Chorea Huntington - Haunting Memory album for free in mp3, flac formats at music.flactopmusic.com. (flactopmusic.com)
  • It is also possible to buy "Chorea Huntington - Haunting Memory" on Amazon, Discogs as listen or rent it on Spotify, Apple Music. (flactopmusic.com)
Syndromes1
  • Chorea can occur with other movement disorders in certain neurological syndromes . (hpathy.com)
Choreatic Disorders1
  • Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS . (bvsalud.org)
Development of chorea1
  • Enhanced activity of the direct pathway, or disruption of the inhibitory function of the indirect pathway, leads to the development of chorea. (medlink.com)
Choreoathetosis1
  • Choreoathetosis is the term to describe chorea with a writhing quality. (medlink.com)
Symptomatic2
  • Based on our work and others', we feel that there is an unmet medical need for the symptomatic treatment of chorea in HD," Furr-Stimming said. (medscape.com)
  • Antidopaminergic drugs are the mainstay to achieve symptomatic control of chorea, regardless of the underlying etiology. (medlink.com)
Genetic2
  • Causes of chorea are multifold and include genetic and acquired forms, such as immune-mediated, infectious, toxic, metabolic and vascular causes. (hpathy.com)
  • There is a growing list of genetic causes of chorea as well as seizure disorders in children. (medlink.com)
Disorders1
  • 8 When the inhibitory mechanism of the basal ganglia is reduced, movement disorders such as chorea arise. (ochsnerjournal.org)
Movement3
  • Chorea-acanthocytosis is primarily a neurological disorder that affects movement in many parts of the body. (medlineplus.gov)
  • Chorea is an irregular, rapid, uncontrolled, involuntary, excessive movement of the body parts that seems to move randomly from one part of the body to another. (hpathy.com)
  • 8 The possibility remains that the movement associated with chorea originates somewhere else in the motor system that has yet to be elucidated. (ochsnerjournal.org)
Neurological1
  • Loss of cells (atrophy) in certain brain regions is the major cause of the neurological problems seen in people with chorea-acanthocytosis. (medlineplus.gov)
Gait1
  • The term chorea implies a dancelike distinctive gait. (medscape.com)
Homeopathic2
  • Are you looking for a homeopathic cure for chorea? (hpathy.com)
  • This article discusses the homeopathy treatment of chorea along with the best homeopathic medicine for chorea treatment. (hpathy.com)
Dopamine1
  • Drugs antagonistic to dopamine D2 receptors reduce the chorea of early HD, and some experimental treatments may help to decrease the aggregation of the huntingtin protein. (iresearchnet.com)
Tetrabenazine3
  • Tetrabenazine and deutetrabenazine , both vesicular monoamine transporter 2 (VMAT2) inhibitors, are approved by the US Food and Drug Administration (FDA) for the treatment of HD-related chorea. (medscape.com)
  • But this is not surprising, as in our discussions with FDA before the approval of tetrabenazine, we had to make a case that improvement in chorea does translate into improvement in QoL in patients with HD," Jankovic said. (medscape.com)
  • Xenazine (tetrabenazine) is the first agent approved by the FDA for chorea in Huntington's Disease (HD). (nonclinicaljobs.com)
Ballism1
  • Severe chorea may appear as uncontrollable flailing of the extremities (ie, ballism), which interferes with function. (medscape.com)
Valbenazine2
  • Valbenazine is in the same class as two other drugs already approved for HD-related chorea. (medscape.com)
  • In the KINECT-HD trial, which included almost 130 patients, those who received valbenazine showed significantly greater chorea symptom-improvement scores than those who received matching placebo. (medscape.com)
Fright1
Clinical2
  • He further demonstrated a potential correlation between antibody reactivity and the clinical status, with antibody disappearance on chorea remission. (medscape.com)
  • balance this risk with clinical need for treatment of chorea. (drugs.com)
Severe1
  • Chorea with extremely severe convulsive action. (hpathy.com)
Behavioral1
  • Behavioral changes are a common feature of chorea-acanthocytosis and may be the first sign of this condition. (medlineplus.gov)
Mutations1
  • Mutations in the VPS13A gene cause chorea-acanthocytosis. (medlineplus.gov)
Extremities1
  • After she increased her dose of gabapentin, she developed chorea of the upper extremities, neck, and head. (ochsnerjournal.org)
Greek1
  • The word "chorea" comes from the Greek word for dance. (hpathy.com)
Seizures2
  • Nearly half of all people with chorea-acanthocytosis have seizures. (medlineplus.gov)
  • Within this group, epilepsy is refractory in up to 40 % of patients, who have shown para el control de síntomas refractarios en a decrease in the frequency of seizures with the concomitant use of cannabidiol and conventional antiepileptics, with mild síndromes convulsivos side effects such as diarrhea and drowsiness. (bvsalud.org)
Adults1
  • Vascular disease of the brain is the most common cause of nongenetic chorea in adults. (medlink.com)
Diseases1
  • Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES . (bvsalud.org)
Basal2
  • Conclusions Chorea is thought to appear when the basal ganglia are deregulated. (ochsnerjournal.org)
  • Chorea is thought to arise from deregulations of the basal ganglia. (ochsnerjournal.org)
Psychiatric2
  • After neurologic and psychiatric consultations, chorea in the course of TBE was diagnosed. (cdc.gov)
  • At the time of the study all but two children were screened as having current psychiatric diagnoses with KSADS-PL. The psychiatric diagnoses were not correlated with whether the child had chorea at the time of the study or not. (gla.ac.uk)
VPS13A gene: MedlinePlus Genetics
VPS13A gene: MedlinePlus Genetics (medlineplus.gov)
Showing results for tags 'PANS'. - ACN Latitudes Forums
Showing results for tags 'PANS'. - ACN Latitudes Forums (latitudes.org)
A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD) - Full...
A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD) - Full... (clinicaltrials.gov)
Tardive Dyskinesia Drug Safe, Effective for Huntington's Chorea
Tardive Dyskinesia Drug Safe, Effective for Huntington's Chorea (medscape.com)
FDA Okays Once-Daily Tardive Dyskinesia, Huntington Chorea Drug
FDA Okays Once-Daily Tardive Dyskinesia, Huntington Chorea Drug (medscape.com)
Acute Rheumatic Fever: Information For Clinicians | CDC
Acute Rheumatic Fever: Information For Clinicians | CDC (cdc.gov)
Rochester Epidemiology Project Data Exploration Portal
Rochester Epidemiology Project Data Exploration Portal (cdc.gov)
Movement Disorders | MedlinePlus
Movement Disorders | MedlinePlus (medlineplus.gov)
Movement - unpredictable or jerky: MedlinePlus Medical Encyclopedia
Movement - unpredictable or jerky: MedlinePlus Medical Encyclopedia (medlineplus.gov)
Acute Rheumatic Fever Workup: Approach Considerations, Histologic Findings, Chest Radiography
Acute Rheumatic Fever Workup: Approach Considerations, Histologic Findings, Chest Radiography (medscape.com)
Huntington disease: MedlinePlus Genetics
Huntington disease: MedlinePlus Genetics (medlineplus.gov)
Streptococcal Infections | Strep Throat | MedlinePlus
Streptococcal Infections | Strep Throat | MedlinePlus (medlineplus.gov)
Severe Hypoglycemia Begets Dementia, and Vice Versa
Severe Hypoglycemia Begets Dementia, and Vice Versa (medscape.com)
Health Topics: C: MedlinePlus
Health Topics: C: MedlinePlus (medlineplus.gov)
Acute Rheumatic Fever: Practice Essentials, Pathophysiology, Etiology
Acute Rheumatic Fever: Practice Essentials, Pathophysiology, Etiology (medscape.com)
Huntington Disease: Background, Pathophysiology, Etiology
Huntington Disease: Background, Pathophysiology, Etiology (medscape.com)
Tardive Dyskinesia: Overview, Pathophysiology, Etiology
Tardive Dyskinesia: Overview, Pathophysiology, Etiology (emedicine.medscape.com)
DHEA: MedlinePlus Supplements
DHEA: MedlinePlus Supplements (medlineplus.gov)
Huntington's Disease | HD | MedlinePlus
Huntington's Disease | HD | MedlinePlus (medlineplus.gov)
Systemic Lupus Erythematosus (SLE) Clinical Presentation: History, Physical Examination
Systemic Lupus Erythematosus (SLE) Clinical Presentation: History, Physical Examination (emedicine.medscape.com)
Chorea | National Institute of Neurological Disorders and Stroke
Chorea | National Institute of Neurological Disorders and Stroke (ninds.nih.gov)
Hemifacial Spasm Differential Diagnoses
Hemifacial Spasm Differential Diagnoses (medscape.com)
(emedicine.medscape.com)
Spur Cell Anemia: Practice Essentials, Pathophysiology, Etiology
Spur Cell Anemia: Practice Essentials, Pathophysiology, Etiology (emedicine.medscape.com)
Chorea in Children: Overview, Causes of Chorea, Pathophysiology and General Principles in Treatment of Chorea
Chorea in Children: Overview, Causes of Chorea, Pathophysiology and General Principles in Treatment of Chorea (emedicine.medscape.com)
Spur Cell Anemia Clinical Presentation: History, Physical Examination
Spur Cell Anemia Clinical Presentation: History, Physical Examination (emedicine.medscape.com)
FDA Clears Deutetrabenazine (Austedo) for Huntington's Chorea
FDA Clears Deutetrabenazine (Austedo) for Huntington's Chorea (medscape.com)
Promising Results for Huntington's Disease Chorea Drug
Promising Results for Huntington's Disease Chorea Drug (medscape.com)
Long-term Safety of Deutetrabenazine for Chorea Confirmed
Long-term Safety of Deutetrabenazine for Chorea Confirmed (medscape.com)