AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyAnthropology, Education, Sociology and Social PhenomenaInformation ScienceHealth CarePublication Characteristics
ChondrosarcomaChondrosarcoma, MesenchymalChondromaBone NeoplasmsEnchondromatosisChordomaMyxosarcomaCartilageFemoral NeoplasmsSkull Base NeoplasmsExostoses, Multiple HereditaryNeoplasms, Connective and Soft TissueOsteosarcomaRibsPelvic BonesChondroitinases and Chondroitin LyasesChondromatosis, SynovialProteoglycansOsteochondromaMaxillary NeoplasmsExophthalmosFibrous Dysplasia, MonostoticS100 ProteinsFatal OutcomeMeningiomaMeningeal NeoplasmsPrivacyConfidentialityComputer SecurityInformed ConsentGenetic PrivacyInternetHealth Insurance Portability and Accountability ActBone PlatesEncyclopedias as TopicEncyclopediasDictionaries, MedicalDictionaries as TopicSarcomaBone and BonesSarcoma, EwingLipomatosisHemangiopericytomaHamartomaGlomus TumorLipomaHemangioendotheliomaLymphangiomaRectal NeoplasmsNeoadjuvant TherapyPreoperative CareCombined Modality TherapyAntineoplastic Combined Chemotherapy ProtocolsRadiotherapy, Adjuvant
Chondrosarcoma
A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed)
Chondrosarcoma, Mesenchymal
A rare aggressive variant of chondrosarcoma, characterized by a biphasic histologic pattern of small compact cells intermixed with islands of cartilaginous matrix. Mesenchymal chondrosarcomas have a predilection for flat bones; long tubular bones are rarely affected. They tend to occur in the younger age group and are highly metastatic. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1456)
Chondroma
A benign neoplasm derived from mesodermal cells that form cartilage. It may remain within the substance of a cartilage or bone (true chondroma or enchondroma) or may develop on the surface of a cartilage (ecchondroma or ecchondrosis). (Dorland, 27th ed; Stedman, 25th ed)
Bone Neoplasms
Tumors or cancer located in bone tissue or specific BONES.
Enchondromatosis
Benign growths of cartilage in the metaphyses of several bones.
Chordoma
A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed)
Myxosarcoma
A sarcoma, usually a liposarcoma or malignant fibrous histiocytoma, with an abundant component of myxoid tissue resembling primitive mesenchyme containing connective tissue mucin. (Stedman, 25th ed)
Cartilage
A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.
Femoral Neoplasms
Skull Base Neoplasms
Neoplasms of the base of the skull specifically, differentiated from neoplasms of unspecified sites or bones of the skull (SKULL NEOPLASMS).
Exostoses, Multiple Hereditary
Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.
Neoplasms, Connective and Soft Tissue
Neoplasms developing from some structure of the connective and subcutaneous tissue. The concept does not refer to neoplasms located in connective or soft tissue.
Osteosarcoma
A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
Ribs
A set of twelve curved bones which connect to the vertebral column posteriorly, and terminate anteriorly as costal cartilage. Together, they form a protective cage around the internal thoracic organs.
Pelvic Bones
Bones that constitute each half of the pelvic girdle in VERTEBRATES, formed by fusion of the ILIUM; ISCHIUM; and PUBIC BONE.
Chondroitinases and Chondroitin Lyases
Enzymes which catalyze the elimination of glucuronate residues from chondroitin A,B, and C or which catalyze the hydrolysis of sulfate groups of the 2-acetamido-2-deoxy-D-galactose 6-sulfate units of chondroitin sulfate. EC 4.2.2.-.
Chondromatosis, Synovial
Rare, benign, chronic, progressive metaplasia in which cartilage is formed in the synovial membranes of joints, tendon sheaths, or bursae. Some of the metaplastic foci can become detached producing loose bodies. When the loose bodies undergo secondary calcification, the condition is called synovial osteochondromatosis.
Proteoglycans
Glycoproteins which have a very high polysaccharide content.
Osteochondroma
A cartilage-capped benign tumor that often appears as a stalk on the surface of bone. It is probably a developmental malformation rather than a true neoplasm and is usually found in the metaphysis of the distal femur, proximal tibia, or proximal humerus. Osteochondroma is the most common of benign bone tumors.
Maxillary Neoplasms
Cancer or tumors of the MAXILLA or upper jaw.
Exophthalmos
Abnormal protrusion of both eyes; may be caused by endocrine gland malfunction, malignancy, injury, or paralysis of the extrinsic muscles of the eye.
Fibrous Dysplasia, Monostotic
FIBROUS DYSPLASIA OF BONE involving only one bone.
S100 Proteins
A family of highly acidic calcium-binding proteins found in large concentration in the brain and believed to be glial in origin. They are also found in other organs in the body. They have in common the EF-hand motif (EF HAND MOTIFS) found on a number of calcium binding proteins. The name of this family derives from the property of being soluble in a 100% saturated ammonium sulfate solution.
Fatal Outcome
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
Meningioma
A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
Meningeal Neoplasms
Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.
Privacy
The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)
Confidentiality
The privacy of information and its protection against unauthorized disclosure.
Computer Security
Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.
Informed Consent
Voluntary authorization, by a patient or research subject, with full comprehension of the risks involved, for diagnostic or investigative procedures, and for medical and surgical treatment.
Genetic Privacy
The protection of genetic information about an individual, family, or population group, from unauthorized disclosure.
Internet
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Health Insurance Portability and Accountability Act
Public Law 104-91 enacted in 1996, was designed to improve the efficiency and effectiveness of the healthcare system, protect health insurance coverage for workers and their families, and to protect individual personal health information.
Bone Plates
Implantable fracture fixation devices attached to bone fragments with screws to bridge the fracture gap and shield the fracture site from stress as bone heals. (UMDNS, 1999)
Encyclopedias as Topic
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Encyclopedias
Dictionaries, Medical
Dictionaries as Topic
Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.
Sarcoma
A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
Bone and Bones
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
Sarcoma, Ewing
A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. The tumor occurs usually before the age of 20, about twice as frequently in males as in females.
Lipomatosis
A disorder characterized by the accumulation of encapsulated or unencapsulated tumor-like fatty tissue resembling LIPOMA.
Hemangiopericytoma
A tumor composed of spindle cells with a rich vascular network, which apparently arises from pericytes, cells of smooth muscle origin that lie around small vessels. Benign and malignant hemangiopericytomas exist, and the rarity of these lesions has led to considerable confusion in distinguishing between benign and malignant variants. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1364)
Hamartoma
A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.
Glomus Tumor
A blue-red, extremely painful vascular neoplasm involving a glomeriform arteriovenous anastomosis (glomus body), which may be found anywhere in the skin, most often in the distal portion of the fingers and toes, especially beneath the nail. It is composed of specialized pericytes (sometimes termed glomus cells), usually in single encapsulated nodular masses which may be several millimeters in diameter (From Stedman, 27th ed). CHEMODECTOMA, a tumor of NEURAL CREST origin, is also sometimes called a glomus tumor.
Lipoma
A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.
Hemangioendothelioma
A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Lymphangioma
A benign tumor resulting from a congenital malformation of the lymphatic system. Lymphangioendothelioma is a type of lymphangioma in which endothelial cells are the dominant component.
Rectal Neoplasms
Tumors or cancer of the RECTUM.
Neoadjuvant Therapy
Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.
Preoperative Care
Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)
Combined Modality Therapy
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
Antineoplastic Combined Chemotherapy Protocols
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
Radiotherapy, Adjuvant
Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.

Inhibitory effects of transforming growth factor-beta1 pretreatment on experimental pulmonary metastasis of MCS-1 Chinese hamster mesenchymal chondrosarcoma cells. (1/35)

Recent studies have suggested that transforming growth factor(TGF)-beta1 acts as a multifunctional regulator of cell growth, and also modifies tumor progression and metastasis. In the present study, we investigated the effects of TGF-beta1 on the proliferation and experimental pulmonary metastasis of MCS-1. MCS-1 are undifferentiated type cloned tumor cells established from a mesenchymal chondrosarcoma which spontaneously occurred in the soft tissue of a female Chinese hamster. MCS-1 cells were pretreated with TGF-beta1 (0, 0.05, 0.5, 2, 10 ng/ml) for 72 hours in a medium containing 1% fetal bovine serum, then tested for in vitro growth by the MTT method, in vivo growth by subcutaneous inoculation into athymic nude mice (1 x 10(6) cells/mouse) and experimental pulmonary metastasis by injection into the lateral tail vein of athymic nude mice (5 x 10(4) cells/mouse). TGF-beta1 significantly inhibited in vitro growth of MCS-1, depending on its concentrations, and also experimental metastasis with maximal inhibition at 0.5 or 2 ng/ml treatment compared to untreated controls. TGF-beta1, however, was ineffective for in vivo subcutaneous growth of MCS-1. These results indicated that TGF-beta1 might be an inhibitor of metastasis of mesenchymal chondrosarcomas including other types of non-epitherial cartilage or bone formation tumors.  (+info)

Cell differentiation and matrix gene expression in mesenchymal chondrosarcomas. (2/35)

Mesenchymal chondrosarcomas are small-cell malignancies named as chondrosarcomas due to the focal appearance of cartilage islands. In this study, the use of in situ detection techniques on a large series of mesenchymal chondrosarcoma specimens allowed the identification of tumor-cell differentiation pathways in these neoplasms. We were able to trace all steps of chondrogenesis within mesenchymal chondrosarcoma by using characteristic marker genes of chondrocytic development. Starting from undifferentiated cells, which were negative for vimentin and any other mesenchymal marker, a substantial portion of the cellular (undifferentiated) tumor areas showed a chondroprogenitor phenotype with an onset of expression of vimentin and collagen type IIA. Cells in the chondroid areas showed the full expression panel of mature chondrocytes including type X collagen indicating focal hypertrophic differentiation of the neoplastic chondrocytes. Finally, evidence was found for transdifferentiation of the neoplastic chondrocytes to osteoblast-like cells in areas of neoplastic bone formation. These results establish mesenchymal chondrosarcoma as the very neoplasm of differentiating premesenchymal chondroprogenitor cells. The potential of neoplastic bone formation in mesenchymal chondrosarcoma introduces a new concept of neoplastic (chondrocytic) osteogenesis in musculoskeletal malignant neoplasms, which qualifies the old dogma that neoplastic bone/osteoid formation automatically implies the diagnosis of osteosarcoma.  (+info)

Prostaglandin D synthase (beta-trace) in meningeal hemangiopericytoma. (3/35)

The level of prostaglandin D synthase (PGDS), a major protein constituent of cerebrospinal fluid (CSF), is altered in various brain diseases, including meningitis. However, its role in the brain remains unclear. PGDS is mainly synthesized in the arachnoid cells, the choroid plexus and oligodendrocytes in the central nervous system. Among brain tumors, meningiomas showed intense immunoreactivity to PGDS in the perinuclear region. Thus, PGDS has been considered a specific cell marker of meningioma. In this study, we examined 25 meningeal hemangiopericytomas (HPCs) and found that 16 of the tumors (64%) showed immunoreactivity for PGDS in the perinuclear region. For comparison, 15 meningiomas, 14 soft-tissue HPCs, 1 mesenchymal chondrosarcoma, 3 choroid plexus papillomas, and 7 oligodendrogliomas were also examined. Meningiomas showed positive immunoreactivity for PGDS in 13 cases (80%). Except for one case located at the sacrum, none of the other soft-tissue HPCs showed immunostaining for PGDS. Mesenchymal chondrosarcoma arises in the bones of the skull, and its histological pattern resembles that of HPC; however, it showed no immunoreactivity for PGDS. Neither choroid plexus papillomas nor oligodendrogliomas were immunopositive for PGDS. These findings suggest that meningeal HPCs may have a unique molecular phenotype that is distinct from that of the soft-tissue HPCs. The origin of meningeal HPCs may be more closely related to the arachnoid cells.  (+info)

Chondrosarcoma of bone: an oncological and functional follow-up study. (4/35)

We retrospectively analysed the course of 42 out of 45 patients suffering from different chondrosarcomas which were treated surgically. We found a prospective 5- and 10-year survival of 64% for both time intervals. Follow-up examination was possible in 21 of 45 patients. Most of them were staged as NED, one as AWD, and 8 of 45 were lost to follow-up. From 16 dead patients 12 died of the disease and 4 of unknown but not to tumor related reasons. Survival was depending significantly on the histopathological grade, and the stage according to Enneking's surgical staging system. Eleven out of forty-five patients developed metastases within a mean period of twelve months after surgery. The survival of these patients was significantly reduced. Patients with centrally located tumors exhibited a distinct but non-significant worse survival than those suffering from peripheral tumors. In 18% (8 of 45) recurrence of the tumor was evident within a mean period of 24 months (5-85). Functional evaluation was performed in 21 out of 28 alive patients. After a mean follow-up time of 72 months the mean score was 64% (23-100). Females exhibited a distinct but non-significant better result, the same was observed for peripheral locations compared to centrally located tumors. Regarding age, grade, and line of resection no tendency of any dependence was detected, but worst results were seen in those with a stage III tumor and dedifferentiated CS.  (+info)

Translocation der(13;21)(q10;q10) in skeletal and extraskeletal mesenchymal chondrosarcoma. (5/35)

Cytogenetic studies of mesenchymal chondrosarcoma are few and to date, no specific or recurrent aberrations have been found. In this investigation, the cytogenetic and molecular cytogenetic (spectral karyotypic and fluorescence in situ hybridization) findings for two mesenchymal chondrosarcomas, one arising skeletally and the other extraskeletally, are reported. An identical Robertsonian translocation involving chromosomes 13 and 21 [der(13;21)(q10;q10)] was detected in both cases, possibly representing a characteristic rearrangement for this histopathologic entity. Both cases also exhibited loss of all or a portion of chromosomes 8 and 20 and gain of all or a portion of chromosome 12. The observation of similar chromosomal abnormalities in both skeletal and extraskeletal mesenchymal chondrosarcoma supports a genetic as well as histopathologic relationship between these anatomically distinct neoplasms.  (+info)

Retroperitoneal extraskeletal mesenchymal chondrosarcoma in a dog. (6/35)

A young adult female Mastiff dog developed a large retroperitoneal mass, pleural effusion, and multiple pulmonary and pleural nodules. All masses were diagnosed as mesenchymal subtype chondrosarcomas, using histological and immunohistochemical criteria. Reports of canine extraskeletal mesenchymal chondrosarcomas (EMCs) are rare but involved animals less than 3 years of age in 60% of the cases. This is the first description of this type of tumor developing distant metastases. Evidence from this case and previous reports suggests that EMCs are associated with a poor prognosis.  (+info)

Mesenchymal chondrosarcoma originating from the femoral vein. (7/35)

Mesenchymal chondrosarcoma is a rare variant of chondrosarcomas characterized by a bimorphic pattern with areas of the undifferentiated malignant small cells and well differentiated cartilaginous islands.(1) It occurs most commonly in the bone but can also occur in the extraskeletal soft tissues, the brain, and the meninges. This type of tumor has also been described in the eyelids, parapharyngeal space, mediastinum, and the kidney.(1-5) An origin from the large vessels has not been reported in the medical literature. The authors report a case of mesenchymal chondrosarcoma originating from the femoral vein in a 28-year-old female patient, treated by the wide-margin resection.  (+info)

Cytopathology of mesenchymal chondrosarcomas: a report and comparison of four patients. (8/35)

BACKGROUND: Mesenchymal chondrosarcoma (MC) is an infrequent neoplasm, representing approximately 1% of all chondrosarcomas. Cytologic descriptions of MCs have been confined to rare case reports. In the current report, the authors describe their experience with the cytologic features of four MCs: two primary tumors and two metastatic lesions. METHODS: Four patients were diagnosed with MC at the authors' institution from 1994 to 2002. Three of four patients underwent fine-needle aspiration (FNA) biopsy as part of their diagnosis; in the fourth patient, imprint cytology was performed. Each tumor also received histologic confirmation. RESULTS: The patients studied included three females and one male. In three patients, the tumor presented initially as a soft tissue mass; whereas, in the remaining patient, the MC presented in the tibia. FNA results demonstrated small, oval-to-spindled cells with high nuclear-to-cytoplasmic ratios. Cells occurred singly and in clumps in a background of basophilic extracellular matrix. Histologic examination of each lesion demonstrated biphasic tumors, including focal areas of relatively mature cartilage formation as well as a small cell population. CONCLUSIONS: MC is a rare soft tissue tumor that occurs frequently in extraskeletal locations. FNA of these tumors can be diagnostic if the tumor is sampled appropriately and of critical features, such as the background extracellular matrix, are recognized. Given the propensity of these tumors to metastasize and the poor prognosis of patients with MC, early identification by FNA biopsy may allow earlier, more aggressive interventions.  (+info)

Intracranial extraskeletal mesenchymal chondrosarcoma: Case report<...Intracranial extraskeletal mesenchymal chondrosarcoma: Case report<...
TY - JOUR. T1 - Intracranial extraskeletal mesenchymal chondrosarcoma. T2 - Case report. AU - Bingaman, Kimberly D.. AU - Alleyne, Cargill H.. AU - Olson, Jeffrey J.. PY - 2000/1. Y1 - 2000/1. N2 - OBJECTIVE AND IMPORTANCE: We present a patient with a dural-based intracranial extraskeletal mesenchymal chondrosarcoma, which was initially thought to be an atypical meningioma. This rare tumor should be considered in the differential diagnosis of young adults with an aggressive-appearing dural-based lesion. CLINICAL PRESENTATION: A 21-year-old woman reported a 3- week history of severe headaches and intermittent nausea and vomiting. Neurological examination revealed right optic nerve swelling. Magnetic resonance imaging demonstrated a large, intensely enhancing extra-axial mass, which appeared to originate from the right side of the falx cerebri with significant mass effect. A presumptive diagnosis of meningioma was made. INTERVENTION: The patient underwent preoperative embolization of the lesion ...
https://augusta.pure.elsevier.com/en/publications/intracranial-extraskeletal-mesenchymal-chondrosarcoma-case-report
Extraskeletal Mesenchymal Chondrosarcoma of Shoulder: An Extremely Rare Case | Journal of Orthopaedic Case ReportsExtraskeletal Mesenchymal Chondrosarcoma of Shoulder: An Extremely Rare Case | Journal of Orthopaedic Case Reports
We should be careful in open reduction and internal fixation of fracture and also should consider in mind the diagnosis of pseudoaneurysm during plate removal,
http://test.jocr.co.in/2016/10/10/2250-0685-560-fulltext/
Orbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis | springermedizin.atOrbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis | springermedizin.at
We report on a patient who presented with swelling to the left side of the face accompanied by exophthalmos. Imaging studies revealed a large
https://www.springermedizin.at/orbito-maxillofacial-mesenchymal-chondrosarcoma-with-intracrania/14930916?fulltextView=true
Low-grade extraskeletal osteosarcoma of the chest wall: case report and review of literature | BMC Cancer | Full TextLow-grade extraskeletal osteosarcoma of the chest wall: case report and review of literature | BMC Cancer | Full Text
However, differential diagnosis may be problematic at early stages with other ossified lesions of soft tissues: benign lesions such as myositis ossificans circumscripta (MOC), ossifying lipoma, soft tissue osteoma or chondroma, and ossifying fibromyxoid tumour, as well as malignant lesions such as classical high-grade ESOS, parosteal OS, mesenchymal chondrosarcoma, and synovial sarcoma. MOC is a benign heterotopic ossification of soft tissues characteristically associated with direct trauma [15]. It is one of the most important differential diagnoses, which was initially evoked - based on radiological and/or pathological aspects - in at least 3 out of the 7 reported cases of low-grade ESOS. Furthermore, a number of cases of ESOS presumably arising from MOC have been reported [16-19]. In MOC, both mature and immature bone is seen, as well as a prominent spindle cell and chondroid component, with a specific architecture described as the zonal phenomenon. This phenomenon refers to the presence of ...
https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-10-645
Alvin DeguzmanAlvin Deguzman
Alvin Deguzman, long-time bassist of The Icarus Line, has died. He had been battling a rare form of cancer (mesenchymal chondrosarcoma), and finally lost the fight a few hours ago. As someone who has met him several times over the years, I am genuinely saddened by his passing. He was a cool dude. May you […]. ...
http://theicarusline.co.uk/tag/alvin-deguzman/
Papers with the keyword Gastrointestinal clear cell sarcoma-like tumor | Read by QxMDPapers with the keyword Gastrointestinal clear cell sarcoma-like tumor | Read by QxMD
Ewing sarcoma shows considerable histologic overlap with other round cell tumors. NKX2-2, a homeodomain transcription factor involved in neuroendocrine/glial differentiation and a downstream target of EWSR1-FLI1, has been reported as an immunohistochemical marker for Ewing sarcoma. We assessed the specificity of NKX2-2 for Ewing sarcoma compared with other round cell malignant neoplasms and other soft tissue tumors with EWSR1 translocations. We evaluated whole-tissue sections from 270 cases: 40 Ewing sarcomas (4 with atypical/large cell features), 20 CIC-DUX4 sarcomas, 5 BCOR-CCNB3 sarcomas, 9 unclassified round cell sarcomas, 10 poorly differentiated synovial sarcomas, 10 lymphoblastic lymphomas, 10 alveolar rhabdomyosarcomas, 10 embryonal rhabdomyosarcomas, 10 Merkel cell carcinomas, 10 small cell carcinomas, 20 melanomas, 5 NUT midline carcinomas, 10 Wilms tumors, 10 neuroblastomas, 10 olfactory neuroblastomas, 12 mesenchymal chondrosarcomas, 10 angiomatoid fibrous histiocytomas, 10 clear ...
https://www.readbyqxmd.com/keyword/20384
Dedifferentiated chondrosarcoma with pathological fracture - femur | Radiology Case | Radiopaedia.orgDedifferentiated chondrosarcoma with pathological fracture - femur | Radiology Case | Radiopaedia.org
55 year old male with dedifferentiated chondrosarcoma and pathological fracture. Final Diagnosis: Left proximal femur and soft tissues, en bloc excision: Dedifferentiated chondrosarcoma High grade, grade 3/3 Maximum size 14.6 cm Tumor is ba...
https://radiopaedia.org/cases/dedifferentiated-chondrosarcoma-with-pathological-fracture-femur
Bone: Dedifferentiated chondrosarcomaBone: Dedifferentiated chondrosarcoma
Bone: Dedifferentiated chondrosarcoma, Authors: Andreas F Mavrogenis, Panayiotis J Papagelopoulos. Published in: Atlas Genet Cytogenet Oncol Haematol.
http://atlasgeneticsoncology.org/Tumors/DediffChondrosarcID5337.html
A Study Of Chondrosarcoma, Bone And Cartilage Derived Cancer - Natural Height GrowthA Study Of Chondrosarcoma, Bone And Cartilage Derived Cancer - Natural Height Growth
As for the genetics and causes of the cancer, it has been rather hard to find sources which can determine the cause of it, from the website…. The genetic changes specific to chondrosarcoma continue to be investigated extensively. Although studies have not yet established a specific or recurrent karyotypic feature for any of these tumors, different chondrosarcomas have demonstrated anomalies in several tumor suppressor genes, oncogenes, and transcription factors, including TP53, RAS, EXT1, EXT2, and Sox9. Available cytogenetic and comparative genomic hybridization (CGH) studies reveal changes in some chondrosarcomas, but fail to do so in others. These studies are thus far difficult to interpret.. Based on the available studies, it is likely that chondrosarcomas are generated by a coordinated, multi-step process involving primarily tumor suppressor genes. In fact, the complexity and variety of genetic changes seen in chondrosarcomas may indicate several distinct genetic pathways. Some of the ...
http://www.naturalheightgrowth.com/2012/10/26/a-study-of-chondrosarcoma-bone-and-cartilage-derived-cancer/
Effective adenoviral transfer of IkappaBalpha into human fibroblasts and chondrosarcoma cells reveals that the induction of...Effective adenoviral transfer of IkappaBalpha into human fibroblasts and chondrosarcoma cells reveals that the induction of...
OBJECTIVE: To determine whether, in human fibroblasts and chondrosarcoma cells, the regulation of interleukins (IL)-6, 8, and 11 and matrix metalloproteinases (MMP)-1, 3, and 13, and their tissue inhibitor TIMP-1, depends on the transcription factor nuclear factor-kappaB (NF-kappaB). METHODS: Fibroblasts and chondrosarcoma cells were effectively infected with an adenovirus encoding human IkappaBalpha, and inhibition of NF-kappaB function was observed. The induction of MMP and IL-6, 8, and 11 by various stimuli was assessed by ELISA. RESULTS: The induction of IL-6 and IL-8 clearly depended on NF-kappaB in both fibroblasts and chondrosarcoma cells, irrespective of stimulus, but IkappaBalpha overexpression had little effect on IL-11. MMP-1, -3, and -13 were also inhibited, but TIMP-1 was unaffected. CONCLUSION: NF-kappaB appears to play an important and selective role in MMP induction in human fibroblasts and chondrosarcoma cells. This suggests there are NF-kappaB dependent mechanisms of cartilage ...
http://orca.cf.ac.uk/57288/
Effective adenoviral transfer of IkappaBalpha into human fibroblasts and chondrosarcoma cells reveals that the induction of...Effective adenoviral transfer of IkappaBalpha into human fibroblasts and chondrosarcoma cells reveals that the induction of...
OBJECTIVE: To determine whether, in human fibroblasts and chondrosarcoma cells, the regulation of interleukins (IL)-6, 8, and 11 and matrix metalloproteinases (MMP)-1, 3, and 13, and their tissue inhibitor TIMP-1, depends on the transcription factor nuclear factor-kappaB (NF-kappaB). METHODS: Fibroblasts and chondrosarcoma cells were effectively infected with an adenovirus encoding human IkappaBalpha, and inhibition of NF-kappaB function was observed. The induction of MMP and IL-6, 8, and 11 by various stimuli was assessed by ELISA. RESULTS: The induction of IL-6 and IL-8 clearly depended on NF-kappaB in both fibroblasts and chondrosarcoma cells, irrespective of stimulus, but IkappaBalpha overexpression had little effect on IL-11. MMP-1, -3, and -13 were also inhibited, but TIMP-1 was unaffected. CONCLUSION: NF-kappaB appears to play an important and selective role in MMP induction in human fibroblasts and chondrosarcoma cells. This suggests there are NF-kappaB dependent mechanisms of cartilage
https://www.kennedy.ox.ac.uk/publications/224717
Low-grade chondrosarcoma: sternum | Radiology Case | Radiopaedia.orgLow-grade chondrosarcoma: sternum | Radiology Case | Radiopaedia.org
Chondrosarcomas are a primitive malignant tumor that derives from cartilage cells. It usually appears at the center of a bone segment, with no pre-existing lesions (central chondrosarcoma). It may also be secondary to a pre-existent condition suc...
https://radiopaedia.org/cases/low-grade-chondrosarcoma-sternum
Plus itPlus it
Purpose: Chondrosarcomas are notoriously resistant to cytotoxic chemotherapeutic agents. We sought to identify critical signaling pathways that contribute to their survival and proliferation, and which may provide potential targets for rational therapeutic interventions. Experimental Design: Activation of receptor tyrosine kinases (RTKs) was surveyed using phospho-RTK arrays. S6 phosphorylation and NRAS mutational status were examined in chondrosarcoma primary tumor tissues. Small interfering RNA or small molecule inhibitors against RTKs or downstream signaling proteins were applied to chondrosarcoma cells and changes in biochemical signaling, cell cycle, and cell viability were determined. In vivo anti-tumor activity of BEZ235, a phosphoinositide-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor, was evaluated in a chondrosarcoma xenograft model. Results: Several RTKs were identified as critical mediators of cell growth, but the RTK dependencies varied among cell lines. In ...
http://clincancerres.aacrjournals.org/content/early/2013/06/20/1078-0432.CCR-12-3647
chondrosarcoma in dogs skullchondrosarcoma in dogs skull
Chondrosarcoma can be of several types depending on the type of cells which are present in the tumor and how they appear microscopically. It is composed of transformed cells that produce cartilage. Radiograph of the head revealed lytic lesion with endosteal scalloping (A, arrow) and…, CT scan showed bone destruction of the skull (A) and matrix calcification (A,…, Transverse T1-weighted MRI (A) and its contrastenhanced image (C) showed a slightly low-signal…, Histopathological finding revealed proliferation of…, Histopathological finding revealed proliferation of the atypical chondrocytes (arrows) and cartilaginous component (C).…, NLM Clipboard, Search History, and several other advanced features are temporarily unavailable. Chondrosarcoma that occurs in a long bone of the leg, for example, is typically treated with the amputation of that leg. , Chondrosarcoma is a malignant tumor of the category known as sarcomas. Various types of cancer can affect the skeletal system, and an ...
http://hoangvinhland.com/hm0jiz/3ae29d-chondrosarcoma-in-dogs-skull
NewYork-Presbyterian Queens - ChondrosarcomaNewYork-Presbyterian Queens - Chondrosarcoma
Chondrosarcoma is a type of cancer that develops in cartilage cells. Cartilage is the specialized, gristly connective tissue that is present in adults and the tissue from which most bones develop. Cartilage plays an important role in the growth process. There are many different types of cartilage that are present throughout the body. Chondrosarcoma is a malignant type of bone cancer that primarily affects the cartilage cells of the femur (thighbone), arm, pelvis, and knee. Although less frequent, other areas (such as the ribs) may be affected.. Chondrosarcoma is the second most common type of primary bone cancer. A primary bone cancer is one that originates from bone, as opposed to starting in another organ and then spreading to the bone. This type of cancer rarely affects individuals under age 20 and continues to rise until age 75. The incidence between males and females is equal.. ...
http://www.nyhq.org/diw/content.asp?pageid=P07414
NewYork-Presbyterian Queens - ChondrosarcomaNewYork-Presbyterian Queens - Chondrosarcoma
Chondrosarcoma is a type of cancer that develops in cartilage cells. Cartilage is the specialized, gristly connective tissue that is present in adults and the tissue from which most bones develop. Cartilage plays an important role in the growth process. There are many different types of cartilage that are present throughout the body. Chondrosarcoma is a malignant type of bone cancer that primarily affects the cartilage cells of the femur (thighbone), arm, pelvis, and knee. Although less frequent, other areas (such as the ribs) may be affected.. Chondrosarcoma is the second most common type of primary bone cancer. A primary bone cancer is one that originates from bone, as opposed to starting in another organ and then spreading to the bone. This type of cancer rarely affects individuals under age 20 and continues to rise until age 75. The incidence between males and females is equal.. ...
http://www.nyhq.org/diw/content.asp?PageID=P00113&More=DIW
Electrophoretic and serologic characterization of 56 kDa antigen (M56) with autologous serum derived from a chondrosarcoma...Electrophoretic and serologic characterization of 56 kDa antigen (M56) with autologous serum derived from a chondrosarcoma...
TY - JOUR. T1 - Electrophoretic and serologic characterization of 56 kDa antigen (M56) with autologous serum derived from a chondrosarcoma patient. T2 - A shared antigen of immunoresponses in cancer and autoimmune diseases. AU - Fujiwara, Kazuo. AU - Udono, Heiichiro. AU - Kunisada, Toshiyuki. AU - Kawai, Akira. AU - Inoue, Hajime. AU - Takigawa, Masaharu. AU - Namba, Masayoshi. AU - Nakayama, Eiichi. PY - 1999. Y1 - 1999. N2 - We investigated whether antibodies specific to autologous cancer cells are produced in the peripheral blood of patients with chondrosarcoma. There have been few reports on the investigation of the immune responses, such as autologous antibody production, to chondrosarcoma. Here, tumor-associated antigens were separated by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis and detected by immunoenzymatic amplification. A 56 kDa molecule (M56) was detected in the serum from patients peripheral blood. M56 is ubiquitously expressed in various kinds of ...
https://okayama.pure.elsevier.com/en/publications/electrophoretic-and-serologic-characterization-of-56-kda-antigen-
Mouth Cancer (Chondrosarcoma) in Dogs | petMDMouth Cancer (Chondrosarcoma) in Dogs | petMD
Chondrosarcomas are characteristic for their slow but progressive invasion of the surrounding tissues. These malignant, cancerous tumors originate in the cartilage, the connective tissue between bones.
https://www.petmd.com/dog/conditions/cancer/c_dg_chondrosarcoma_oral?page=show
Clear-cell chondrosarcoma of the maxilla Report of a caseClear-cell chondrosarcoma of the maxilla Report of a case
Clear-cell chondrosarcoma is a variant of chondrosarcoma which is characterized by a typical histomorphology and a very slow rate of growth. A case is presented in which the tumor was located in the maxilla. show less ...
https://dspace.library.uu.nl/handle/1874/24306
Chondrosarcoma: Causes, Symptoms, Diagnosis and TreatmentChondrosarcoma: Causes, Symptoms, Diagnosis and Treatment
Learn about the rare cancer Chondrosarcoma, its symptoms, causes, diagnosis methods, and treatment options available to overcome the problem.
https://www.healthadvicer.com/chondrosarcoma-causes-symptoms-treatment.html
Chondrosarcoma | Johns Hopkins MedicineChondrosarcoma | Johns Hopkins Medicine
Chondrosarcoma is a malignant type of bone cancer that primarily affects the cartilage cells of the femur, arm, pelvis, knee, and spine.
https://www.hopkinsmedicine.org/health/conditions-and-diseases/sarcoma/chondrosarcoma
ChondrosarcomaChondrosarcoma
Chondrosarcoma is a malignant type of bone cancer that primarily affects the cartilage cells of the femur, arm, pelvis, knee, and spine.
http://healthlibrary.brighamandwomens.org/Library/Encyclopedia/85,P00113
Treatment Options for Chondrosarcoma | Stanford Health CareTreatment Options for Chondrosarcoma | Stanford Health Care
Chondrosarcoma treatments include chemotherapy, radiation therapy, targeted therapies, and surgery, to remove the mass and reduce the likelihood of return.
https://stanfordhealthcare.org/medical-conditions/cancer/chondrosarcoma/treatments.html
Polarity and Ploidy in Peripheral Chondrosarcoma Research GrantPolarity and Ploidy in Peripheral Chondrosarcoma Research Grant
Kevin B. Jones, MD of University of Utah - Huntsman Cancer Institute receives grant for Polarity and Ploidy in Peripheral Chondrosarcoma research.
https://www.curesarcoma.org/grant/polarity-and-ploidy-in-peripheral-chondrosarcoma/
Chondrosarcoma | Coliseum Health SystemChondrosarcoma | Coliseum Health System
Learn more about Chondrosarcoma at Coliseum Health System DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision .....
https://coliseumhealthsystem.com/hl/?/227283/sp
Supplementary Material for: MiR-129-5p Inhibits Proliferation and Invasion of Chondrosarcoma Cells by Regulating SOX4/Wnt/β...Supplementary Material for: MiR-129-5p Inhibits Proliferation and Invasion of Chondrosarcoma Cells by Regulating SOX4/Wnt/β...
Supplementary Material for: MiR-129-5p Inhibits Proliferation and Invasion of Chondrosarcoma Cells by Regulating SOX4/Wnt/β-Catenin Signaling Pathway
https://karger.figshare.com/articles/Supplementary_Material_for_MiR-129-5p_Inhibits_Proliferation_and_Invasion_of_Chondrosarcoma_Cells_by_Regulating_SOX4_Wnt_-Catenin_Signaling_Pathway/5048470/1
GLC cancerGLC cancer
Chondrosarcoma is a rare type of cancer that usually begins in the bones, but can sometimes occur in the soft tissue near bones. The most common locations for chondrosarcoma tumors are in the pelvis, hip and shoulder. More rarely, the base of the skull is affected. ...
https://www.growthbeans.com/glc_cancer.html
Mca June 2011 Exam Paper - 442 WordsMca June 2011 Exam Paper - 442 Words
No. of Printed Pages : 3 MCA (Revised) MCS-012 Term-End Examination tr) June, 2011 cNI 0 ,--. MCS-012 : COMPUTER ORGANISATION & ASSEMBLY LANGUAGE
http://www.studymode.com/essays/Mca-June-2011-Exam-Paper-1021111.html
Most recent papers with the keyword ewing sarcoma neuroblastoma | Read by QxMDMost recent papers with the keyword ewing sarcoma neuroblastoma | Read by QxMD
AIMS: Neuroblastoma shows considerable histological overlap with other small round blue cell tumours. PHOX2B, a transcription factor that is essential for autonomic nervous system development, has been reported as an immunohistochemical marker for neuroblastoma. The aim of this study was to validate the specificity and diagnostic utility of PHOX2B for peripheral neuroblastic tumours. METHODS AND RESULTS: We evaluated 240 cases (133 in whole-tissue sections; 107 in tissue microarrays), including 76 peripheral neuroblastic tumours (median age 2 years; including four adults) and 164 other tumours: 44 Wilms tumours; 20 Ewing sarcomas; 10 each of CIC-rearranged round cell sarcomas, poorly differentiated synovial sarcomas, lymphoblastic lymphomas, alveolar rhabdomyosarcomas, embryonal rhabdomyosarcomas, mesenchymal chondrosarcomas, Merkel cell carcinomas, olfactory neuroblastomas, and melanomas; and five each of NUT midline carcinomas and desmoplastic small round cell tumours ...
https://www.readbyqxmd.com/keyword/38244
IL-8 increases integrin expression and cell motility in human chondrosarcoma cells - Lee - 2011 - Journal of Cellular...IL-8 increases integrin expression and cell motility in human chondrosarcoma cells - Lee - 2011 - Journal of Cellular...
Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant metastasis. Chondrosarcoma shows a predilection for metastasis to the lungs. Interleukin-8 (IL-8), a chemokine with a defining CXC amino acid motif, is known to possess tumorigenic and proangiogenic properties. Over-expression of IL-8 has been detected in many human tumors. However, the effects of IL-8 in migration and integrin expression in chondrosarcoma cells are largely unknown. In this study, we found that IL-8 increased the migration and the expression of αvβ3 integrin in human chondrosarcoma cells. Activations of phosphatidylinositol 3-kinase (PI3K), Akt, and AP-1 pathways after IL-8 treatment were demonstrated, and IL-8-induced expression of integrin and migration activity was inhibited by the specific inhibitor and mutant of PI3K, Akt, and AP-1 cascades. Taken together, our results indicated that IL-8 enhances the migration of chondrosarcoma cells by increasing αvβ3 integrin ...
http://onlinelibrary.wiley.com/doi/10.1002/jcb.23179/abstract
Functional genomic analyses of the impact of global hypomethylation an by Christopher Allan HammFunctional genomic analyses of the impact of global hypomethylation an by Christopher Allan Hamm
Chondrosarcomas are malignant cartilage tumors that do not respond to traditional chemotherapy or radiation. The 5-year survival rate of histologic grade III chondrosarcoma is less than 30%. To achieve a greater understanding of chondrosarcoma tumorigenesis, a model for human chondrosarcoma has been established in a rat system. The model, known as the Swarm rat chondrosarcoma (SRC), resembles human chondrosarcoma and provides a system to study tumor growth and progression. Here we examined the influence of the tumor microenvironment and the impact of genome-wide hypomethylation on the behavior of SRC tumors, two factors known to contribute fundamentally to the development and progression of solid tumors. Previous studies with SRC revealed that tumor microenvironment can significantly influence chondrosarcoma malignancy, but the underlying biologic mechanisms have not been defined. To address this issue we carried out epigenetic and gene expression studies on the SRC tumors that were initiated at
http://ir.uiowa.edu/etd/372/
Chondrosarcoma: Its treatment by radiation, hyperthermia and bleomycin<...Chondrosarcoma: Its treatment by radiation, hyperthermia and bleomycin<...
TY - JOUR. T1 - Chondrosarcoma. T2 - Its treatment by radiation, hyperthermia and bleomycin. AU - Okuyama, S.. AU - Itoh, M.. AU - Tanaka, K.. AU - Matsuzawa, T.. PY - 1978/12/1. Y1 - 1978/12/1. N2 - A case of chondrosarcoma of the mandible of surgical failure was treated by radiation, hyperthermia, and bleomycin. The treatment resulted in selective necrosis of the tumor. This can be designated as perpetuation principle of radiothermotherapy because bleomycin may inhibit the repair processes of heat and radiation damage. This principle appears to offer selectivity of the therapeutic effects, to open a way to treatment of those radioresistant selectivity of the therapeutic effects, open a way to treatment of those radioresistant malignancies, and to enhance curability of various medium-sensitive tumors. Additionally, a course of large-dose glutathione infusion was confirmed to promptly alleviate radiation dermatitis and mucositis.. AB - A case of chondrosarcoma of the mandible of surgical failure ...
https://tohoku.pure.elsevier.com/en/publications/chondrosarcoma-its-treatment-by-radiation-hyperthermia-and-bleomy
ChondrosarcomaChondrosarcoma
Imaging studies - including radiographs (x-rays), computerized tomography (CT), and magnetic resonance imaging (MRI) - are often used to make a presumptive diagnosis of chondrosarcoma. However, a definitive diagnosis depends on the identification of malignant cancer cells producing cartilage in a biopsy specimen that has been examined by a pathologist. In a few cases, usually of highly anaplastic tumors, immunohistochemistry (IHC)is required.. There are no blood tests currently available to enable an oncologist to render a diagnosis of chondrosarcoma. The most characteristic imaging findings are usually obtained with CT.. Nearly all chondrosarcoma patients appear to be in good health. Often, patients are not aware of the growing tumor until there is a noticeable lump or pain. Earlier diagnosis is generally accidental, when a patient undergoes testing for another problem and physicians discover the cancer. Occasionally the first symptom will be a broken bone at the cancerous site. Any broken ...
http://www.fightbonetumors.com/Chondrosarcoma.html
Chondrosarcoma facts, information, pictures | Encyclopedia.com articles about ChondrosarcomaChondrosarcoma facts, information, pictures | Encyclopedia.com articles about Chondrosarcoma
Get information, facts, and pictures about Chondrosarcoma at Encyclopedia.com. Make research projects and school reports about Chondrosarcoma easy with credible articles from our FREE, online encyclopedia and dictionary.
http://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/chondrosarcoma
Chondrosarcoma of the greater cornu of the hyoid: a case report and literature review.Chondrosarcoma of the greater cornu of the hyoid: a case report and literature review.
We report an unusual case of a young woman with chondrosarcoma affecting the greater cornu of the hyoid bone. Only a handful of reports of primary chondrosarcoma involving the hyoid exist in the world literature. The case described presented as a swe
http://www.biomedsearch.com/nih/Chondrosarcoma-greater-cornu-hyoid-case/18833525.html
An extraskeletal chondrosarcoma of the maxilla. A case report<...An extraskeletal chondrosarcoma of the maxilla. A case report<...
TY - JOUR. T1 - An extraskeletal chondrosarcoma of the maxilla. A case report. AU - Nishioka, Gary. AU - Holt, G. Richard. AU - Aufdemorte, Thomas B.. AU - Triplett, Robert G.. PY - 1995/2. Y1 - 1995/2. UR - http://www.scopus.com/inward/record.url?scp=0028858834&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0028858834&partnerID=8YFLogxK. U2 - 10.1016/0278-2391(95)90401-8. DO - 10.1016/0278-2391(95)90401-8. M3 - Article. C2 - 7830187. AN - SCOPUS:0028858834. VL - 53. SP - 193. EP - 195. JO - Journal of Oral and Maxillofacial Surgery. JF - Journal of Oral and Maxillofacial Surgery. SN - 0278-2391. IS - 2. ER - ...
https://scholars.uthscsa.edu/en/publications/an-extraskeletal-chondrosarcoma-of-the-maxilla-a-case-report
Chondrosarcoma of the Thorax - Semantic ScholarChondrosarcoma of the Thorax - Semantic Scholar
Although a rare entity, chondrosarcoma is the most common malignant tumor of the chest wall. Most patients present with an enlarging, painful anterior chest wall mass arising from the costochondrosternal junction. CT scan with intravenous contrast is the gold standard radiographic study for diagnosis and operative planning. Contrary to previous dictum, resection may be performed in an appropriate surgical candidate based on imaging characteristics or image-guided percutaneous biopsy results; incisional biopsy is rarely required. The keys to successful treatment are early recognition and radical excision with adequate margins, as chondrosarcoma is relatively resistant to radiotherapy and conventional cytotoxic chemotherapy. Overall survival is excellent in most surgical series from experienced centers. Complete excision with widely negative microscopic margins at the initial operation is of the utmost importance, as local recurrence portends systemic metastasis and eventual tumor-related mortality. This
https://www.semanticscholar.org/paper/Chondrosarcoma-of-the-Thorax-Rascoe-Reznik/6b342e7d01a05869f85ab6f95be18a00a651a47a
A chondrosarcoma in the anterior mediastinum mimicking a thymoma - Forskning - Region HovedstadenA chondrosarcoma in the anterior mediastinum mimicking a thymoma - Forskning - Region Hovedstaden
A chondrosarcoma in the anterior mediastinum is a rare finding with a relatively good prognosis. We describe a case of a 75-year-old man with a 2-year history of neck discomfort and weight loss. Imaging showed a homogenous tumor with a minor compression on the anterior part of the heart. It had close relation to the ribs, no surrounding fat, and a thymoma was suspected. Biopsy prior to surgery was impossible due to the location of the tumor. Unfortunately, final pathology from the surgical specimen revealed a chondrosarcoma. ...
https://research.regionh.dk/da/publications/a-chondrosarcoma-in-the-anterior-mediastinum-mimicking-a-thymoma
Old Maid Cat Lady: Cancer in Cats: ChondrosarcomaOld Maid Cat Lady: Cancer in Cats: Chondrosarcoma
Depending on the type of chondrosarcoma, it may spread slowly or very rapidly. Its presently unknown what causes this type of cancer. This is partially because it is so unusual that there are not a lot of cases to study. A higher incidence of nasal CSAs among cats living in urban areas may indicate a link to air pollution. The type affecting bones has been found to contain viruses in the cells of the tumor, suggesting a viral connection. Some bone tumors develop on the site of a previous fracture, which may mean theres a link with the bodys cells that heal a broken bone. But its believed that several factors combine with each unique cats physiology to cause the cells to become cancerous ...
http://oldmaidcatlady.blogspot.com/2013/05/cancer-in-cats-chondrosarcoma.html
Throat Cancer (Chondrosarcoma) in Dogs | PetMDThroat Cancer (Chondrosarcoma) in Dogs | PetMD
A chondrosarcoma is one of several types of laryngeal tumors that can effect the larynx and trachea of a dog. This is a relatively rare and fast spreading tumor that originates in the cartilage, a connective collagenous tissue that is found throughout the body.
https://www.petmd.com/dog/conditions/cancer/c_dg_chondrosarcoma_larynx_trachea
Treatments for chondrosarcoma - Canadian Cancer SocietyTreatments for chondrosarcoma - Canadian Cancer Society
The following are treatment options for all stages of chondrosarcoma. The types of treatments given are based on the unique needs of the person with cancer.
https://www.cancer.ca/en/cancer-information/cancer-type/bone/treatment/chondrosarcoma/?region=qc
Gentaur Molecular :US Biomax \ Osteosarcoma and chondrosarcoma tissue array, with stage, grade and TNM data, 80 cases 80 cores,...Gentaur Molecular :US Biomax \ Osteosarcoma and chondrosarcoma tissue array, with stage, grade and TNM data, 80 cases 80 cores,...
Gentaur molecular products has all kinds of products like :search , US Biomax \ Osteosarcoma and chondrosarcoma tissue array, with stage, grade and TNM data, 80 cases_80 cores, replacing OS801 and BC26111; ihc Anti-Actin confirmed \ OS802 for more molecular products just contact us
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Chondrosarcoma - OzRadOncChondrosarcoma - OzRadOnc
Pain is the usual presenting symptom; alternatively the tumour may be found incidentally on imaging. Signs are localise to the involved bone. Imaging appearances are difficult as most chondrosarcomas resemble benign chondroma. The most common features are of central lucency with expansion and thickening of the overlying cortex.. ...
http://ozradonc.wikidot.com/pathology:chondrosarcoma
Other shared propranolol examen oralOther shared propranolol examen oral
These deficits are summarized in Display 10-17, the lesions are charac- terized by a bimorphic pattern that is composed of highly undifferentiated small round cells and islands of well- differentiated hyaline cartilage. Judicial procedures It is exaemn established that governing body disciplinary procedures Propranolo subject to the propranтlol of natural justice. L.
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Dedifferentiated chondrosarcomas of the larynx: a report of two cases and review of the literatureDedifferentiated chondrosarcomas of the larynx: a report of two cases and review of the literature
CAMMC of the larynx are rare tumors but have a better prognosis than their axial counterparts (mean, 6 mo). Initial voice-sparing surgery can be followed with more aggressive surgery if recurrences develop.
https://pubmed.ncbi.nlm.nih.gov/12160266/
Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine - Full Text View - ClinicalTrials...Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine - Full Text View - ClinicalTrials...
The primary purpose of this study is to determine if the administration of a higher dose would decrease the chance of tumor recurrence, compared to the risk of tumor recurrence with a lower dose. Most of the treatment will be given protons, but participants may receive a small portion of treatment with x-rays, because less radiation is given to the skin with x-rays. This study uses two slightly different doses of radiation It is not clear at this time which of the dose levels is better ...
https://clinicaltrials.gov/ct2/show/NCT00592748
Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine - Full Text View - ClinicalTrials...Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine - Full Text View - ClinicalTrials...
The primary purpose of this study is to determine if the administration of a higher dose would decrease the chance of tumor recurrence, compared to the risk of tumor recurrence with a lower dose. Most of the treatment will be given protons, but participants may receive a small portion of treatment with x-rays, because less radiation is given to the skin with x-rays. This study uses two slightly different doses of radiation It is not clear at this time which of the dose levels is better ...
https://clinicaltrials.gov/ct2/show/NCT00592748?cond=%22chordoma%22&rank=11
MedPix Case - chondrosarcoma, low gradeMedPix Case - chondrosarcoma, low grade
Axial T2 weighted MR image again demonstrates the mass with typical high signal lobular growth pattern of cartilage representing cap.
https://medpix.nlm.nih.gov/case?id=0eab9c23-8a6b-4e2a-8088-0005c8edab97&quiz=t
Chondrosarcoma treatment in clinics of Kleinbartloff, prices, patient reviews - DocLandmedChondrosarcoma treatment in clinics of Kleinbartloff, prices, patient reviews - DocLandmed
When I was diagnosed with ovarian cancer, the first reaction was of course panic, and then I Packed up and started to look for information on the Internet and on the forums. Im still grateful to all those people who write reviews about their appeal to different professionals - I this information helped to survive. That is why I write about how I got to Israel, and how I was able to overcome the disease.The purpose of my search information on the Internet to understand where and how to treat ovarian cancer, what are my prospects in General? The important thing is that I knew we must act quickly. Of course, I wanted to go to a top specialist because of the ability to experiment just wasnt there.I immediately realized that I wanted to be treated in Israel, as there is a percentage of cure from cancer is very high, including ovarian cancer. This treatment is cheaper than, say, the USA or Germany, for me it was also an important argument. I only had to choose the doctor. About Professor Moshe Inbar ...
https://doclandmed.com/en/germany/klyajnbartloff/oncology/chondrosarcoma
Leksell Top 25 - Since 2005Leksell Top 25 - Since 2005
The actuarial 5- and 10-year survival rates after GKS were 80 and 53%, respectively. The actuarial 5- and 10-year local tumor control (LTC) rates after single or multiple GKS sessions were 76 and 67%, respectively. All patients with low-grade chondrosarcomas achieved good LTC. A tumor volume of less than 20 ml significantly affected the high rate of LTC (p = 0.0182). No patient had adverse radiation effects, other than one in whom facial numbness worsened despite successful tumor control. ...
https://thejns.org/collection/leksell-top-25-since-2005?authf=Iizuka%2C+Hiroshi&pageSize=10&sort=datedescending
Search Results | jnsSearch Results | jns
The actuarial 5- and 10-year survival rates after GKS were 80 and 53%, respectively. The actuarial 5- and 10-year local tumor control (LTC) rates after single or multiple GKS sessions were 76 and 67%, respectively. All patients with low-grade chondrosarcomas achieved good LTC. A tumor volume of less than 20 ml significantly affected the high rate of LTC (p = 0.0182). No patient had adverse radiation effects, other than one in whom facial numbness worsened despite successful tumor control. ...
https://thejns.org/search?authf=Koike%2C+Joji&f_0=author&pageSize=10&q_0=Toshinori+Hasegawa&sort=relevance
My Results are in ~ Its Cancer - Shizzle DesignMy Results are in ~ Its Cancer - Shizzle Design
Dr. Post called with my biopsy results and told me I have a very rare form of bone cancer called chondrosarcoma. I am very blessed because it is Grade One meaning, its treatable through surgery and the percentage of recurrence is very low. Thank you Jesus! Chemo and radiation wont help my type of cancer so it…
https://www.shizzle-design.com/2015/09/my-diagnosis-from-the-biopsy-is-in/?replytocom=2885
Bone sarcomaBone sarcoma
Clear cell Clear cell chondrosarcomas are rare, slow-growing, and seldom spread. Mesenchymal Mesenchymal chondrosarcomas can ... "Mesenchymal chondrosarcoma , Radiology Reference Article , Radiopaedia.org". Radiopaedia. Müller S, Söder S, Oliveira AM, ... Most chondrosarcomas develop in the pelvis, legs or arms. Benign counterparts are known as enchondromas. Chondrosarcomas are ... "Type II collagen as specific marker for mesenchymal chondrosarcomas compared to other small cell sarcomas of the skeleton". Mod ...
https://en.wikipedia.org/wiki/Bone_sarcoma
IRF2BP2 (gene)IRF2BP2 (gene)
... in mesenchymal chondrosarcoma". PLOS ONE. 7 (11): e49705. Bibcode:2012PLoSO...749705N. doi:10.1371/journal.pone.0049705. PMC ...
https://en.wikipedia.org/wiki/IRF2BP2_(gene)
Randy Miller (musician)Randy Miller (musician)
Miller was diagnosed with mesenchymal chondrosarcoma, a form of bone cancer, in 2008, the same year that With Arrows, With ...
https://en.wikipedia.org/wiki/Randy_Miller_(musician)
Cancer epigeneticsCancer epigenetics
Expression of epigenetic modifiers such as that of the BMI1 component of the PRC1 complex is deregulated in chondrosarcoma, ... Sarcomas comprise a large number of rare, histogenetically heterogeneous mesenchymal tumors that, for example, include ... Similarly, expression of another epigenetic modifier, the LSD1 histone demethylase, is increased in chondrosarcoma, Ewing's ... Bennani-Baiti IM (December 2011). "Epigenetic and epigenomic mechanisms shape sarcoma and other mesenchymal tumor pathogenesis ...
https://en.wikipedia.org/wiki/Cancer_epigenetics
List of MeSH codes (C04)List of MeSH codes (C04)
... chondrosarcoma MeSH C04.557.450.565.280.280 - chondrosarcoma, mesenchymal MeSH C04.557.450.565.380 - giant cell tumors MeSH ... chondrosarcoma MeSH C04.557.450.795.300.280 - chondrosarcoma, mesenchymal MeSH C04.557.450.795.350 - fibrosarcoma MeSH C04.557. ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C04)
Small-blue-round-cell tumorSmall-blue-round-cell tumor
... the more common fetal and embryonal types do not Merkel cell carcinoma Mesenchymal chondrosarcoma Endometrial stromal ...
https://en.wikipedia.org/wiki/Small-blue-round-cell_tumor
International Classification of Diseases for OncologyInternational Classification of Diseases for Oncology
Myxoid chondrosarcoma M9240/3 Mesenchymal chondrosarcoma M9241/0 Chondromyxoid fibroma M9242/3 Clear cell chondrosarcoma M9243/ ... NOS Mixed mesenchymal tumor M8990/3 Mesenchymoma, malignant Mixed mesenchymal sarcoma M8991/3 Embryonal sarcoma M9000/0 Brenner ... M9221/0 Juxtacortical chondroma Periosteal chondroma M9221/3 Juxtacortical chondrosarcoma Periosteal chondrosarcoma M9230/0 ... 3 Dedifferentiated chondrosarcoma M9250/1 giant cell tumor of bone, NOS Osteoclastoma, NOS M9250/3 Giant cell tumor of bone, ...
https://en.wikipedia.org/wiki/International_Classification_of_Diseases_for_Oncology
SarcomaSarcoma
Yang J, Ren Z, Du X, Hao M, Zhou W (27 October 2014). "The role of mesenchymal stem/progenitor cells in sarcoma: update and ... Some sarcomas, such as leiomyosarcoma, chondrosarcoma, and gastrointestinal stromal tumor (GIST), are more common in adults ... A sarcoma is a malignant tumor, a type of cancer that arises from transformed cells of mesenchymal (connective tissue) origin. ... These subtypes are as follows: Osteosarcoma Chondrosarcoma Poorly differentiated round/spindle cell tumors (includes Ewing ...
https://en.wikipedia.org/wiki/Sarcoma
Index of trauma and orthopaedics articlesIndex of trauma and orthopaedics articles
Mesenchymal chondrosarcoma - Metaphysis - Metatarsophalangeal joint sprain - Microfracture surgery - Milch classification - ... Myxoid chondrosarcoma National hip fracture database - Neer classification - Neer impingement sign - Neer's prosthesis - ... Chondrosarcoma - Chopart's fracture-dislocation - Clarke's test - Clavicle fracture - Clay-shoveler fracture - Cleidocranial ...
https://en.wikipedia.org/wiki/Index_of_trauma_and_orthopaedics_articles
ChondrosarcomaChondrosarcoma
IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal ... CT scan and gross pathology of a chondrosarcoma 2012-12-18 "Chondrosarcoma : Cancerbackup". Archived from the original on 2008- ... Therapeutic molecular targets in human chondrosarcoma .Int J Exp Pathol 2010; 91:387-93 Media related to Chondrosarcoma at ... A chondrosarcoma is a member of a category of tumors of bone and soft tissue known as sarcomas. About 30% of bone sarcomas are ...
https://en.wikipedia.org/wiki/Chondrosarcoma
Extraskeletal myxoid chondrosarcomaExtraskeletal myxoid chondrosarcoma
... (EMC) is a rare low-grade malignant mesenchymal neoplasm of the soft tissues, that differs ... "Myxoid Chondrosarcoma - an overview , ScienceDirect Topics". www.sciencedirect.com. Retrieved 2019-02-04. Rubin, Brian P.; ... Molecular analysis of the fusion of EWS to an orphan nuclear receptor gene in extraskeletal myxoid chondrosarcoma. OCLC ... when they discussed the different species of extraskeletal chondrosarcoma, but EMC concept was firstly proposed in 1972 by ...
https://en.wikipedia.org/wiki/Extraskeletal_myxoid_chondrosarcoma
ChondroblastChondroblast
Chondrosarcoma is a more malignant type of tumor, but most are low grade tumors and often appear in the axial skeletal region. ... As suggested in the name, mesenchymal progenitors originate from the mesoderm. These cells, when forming from the mesoderm, ... Day, Timothy F.; Guo, Xizhi; Garrett-Beal, Lisa; Yang, Yingzi (2005). "Wnt/β-Catenin Signaling in Mesenchymal Progenitors ... Chondroblasts, or perichondrial cells, is the name given to mesenchymal progenitor cells in situ which, from endochondral ...
https://en.wikipedia.org/wiki/Chondroblast
Osteoid osteomaOsteoid osteoma
Chondrosarcoma *Mesenchymal chondrosarcoma. *Myxoid chondrosarcoma. *Osteochondroma *Osteochondromatosis. *Chondromyxoid ...
https://en.wikipedia.org/wiki/Osteoid_osteoma
WHO classification of tumours of the central nervous systemWHO classification of tumours of the central nervous system
3.2 Mesenchymal tumours 3.2.1 Lipoma (ICD-O 8850/0) 3.2.2 Angiolipoma (ICD-O 8861/0) 3.2.3 Hibernoma (ICD-O 8880/0) 3.2.4 ... 3.2.13 Chondrosarcoma (ICD-O 9220/3) 3.2.14 Osteoma (ICD-O 9180/0) 3.2.15 Osteosarcoma (ICD-O 9180/3) 3.2.16 Osteochondroma ( ...
https://en.wikipedia.org/wiki/WHO_classification_of_tumours_of_the_central_nervous_system
IFFO1IFFO1
However, the gene has been found to be highly expressed in chondrosarcoma. Chondrosarcoma is the cancer of the cells that ... especially mesenchymal cells. The vimentin protein is also responsible for maintaining cell shape, integrity of the cytoplasm, ... Therefore, there seems to be an association between IFFO1's filamentous characteristic and chondrosarcoma. One nuclear export ...
https://en.wikipedia.org/wiki/IFFO1
MetaphysisMetaphysis
The metaphysis contains a diverse population of cells including mesenchymal stem cells, which give rise to bone and fat cells, ... Metaphyseal tumors or lesions include osteosarcoma, chondrosarcoma, fibrosarcoma, osteoblastoma, enchondroma, fibrous dysplasia ...
https://en.wikipedia.org/wiki/Metaphysis
Ectomesenchymal chondromyxoid tumorEctomesenchymal chondromyxoid tumor
... mesenchymal cells. There are some who think it is a myoepithelial tumor type. Derived from ectomesenchymal cells migrating from ... extraskeletal myxoid chondrosarcoma, focal oral mucinosis, and an ossifying fibromyxoid tumor of soft parts. Exceedingly rare, ...
https://en.wikipedia.org/wiki/Ectomesenchymal_chondromyxoid_tumor
List of cancer typesList of cancer types
... each of which develop from cells originating in mesenchymal cells outside of the bone marrow. Lymphoma and leukemia: These two ... Chondrosarcoma Ewing's sarcoma Malignant fibrous histiocytoma of bone/osteosarcoma Osteosarcoma Rhabdomyosarcoma Leiomyosarcoma ...
https://en.wikipedia.org/wiki/List_of_cancer_types
ChondroblastomaChondroblastoma
Romeo et al have observed chondroblastoma neoplasms to be composed of mesenchymal cells that have completed normal ... clear cell chondrosarcomas, and enchondromas (this list is not exhaustive). Chondroblastoma has not been known to spontaneously ... These findings suggest that chondroblastoma is derived from a mesenchymal cell undergoing chondrogenesis via active growth- ... any definitive determinations regarding the origin of this neoplasm are not possible because of the plasticity of mesenchymal ...
https://en.wikipedia.org/wiki/Chondroblastoma
Kostniakomięsak, wolna encyklopediaKostniakomięsak, wolna encyklopedia
Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of Cdkn2. „J Pathol". ... Osteosarcoma, chondrosarcoma, and Ewing's sarcoma: National Cancer Data Base Report. „Clin Orthop Relat Res". 459, s. 40-7, Jun ... Review of therapeutic strategies for osteosarcoma, chondrosarcoma, and Ewing's sarcoma.. „Med Sci Monit". 17 (8), s. RA177-190 ...
https://pl.wikipedia.org/wiki/Kostniakomięsak
List of OMIM disorder codesList of OMIM disorder codes
GDF5 Chondrosarcoma; 215300; EXT1 Chondrosarcoma, extraskeletal myxoid; 612237; TAF15 Chondrosarcoma, extraskeletal myxoid; ... RSPO4 Anterior segment mesenchymal dysgenesis; 107250; FOXE3 Anterior segment mesenchymal dysgenesis; 107250; PITX3 ... 612237; TFG Chondrosarcoma, extraskeletal myxoid; 612237; CSMF Chorea, hereditary benign; 118700; NKX2-1 Choreoacanthocytosis; ...
https://en.wikipedia.org/wiki/List_of_OMIM_disorder_codes
OsteosarcomaOsteosarcoma
Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and ... Differential diagnosis of the osteosarcoma of the skull in particular includes, among others, chondrosarcoma and the ...
https://en.wikipedia.org/wiki/Osteosarcoma
Index of oncology articlesIndex of oncology articles
... chondrosarcoma - chordoma - chorioallantoic membrane - choriocarcinoma - choroid plexus tumor - CHPP - chronic granulocytic ... mesenchymal - mesenteric membrane - mesna - mesonephroma - mesothelioma - metaplasia - metaplastic carcinoma - metastasectomy ...
https://en.wikipedia.org/wiki/Index_of_oncology_articles
TBX3TBX3
Volckaert T, De Langhe SP (March 2015). "Wnt and FGF mediated epithelial-mesenchymal crosstalk during lung development". ... chondrosarcoma, fibrosarcoma, liposarcoma, rhabdomyosarcoma and synovial sarcoma) and there is compelling evidence that it ...
https://en.wikipedia.org/wiki/TBX3
RhabdomyosarcomaRhabdomyosarcoma
... (RMS), is a highly aggressive form of cancer that develops from mesenchymal cells that have failed to fully ... chondrosarcoma, or angiosarcoma". The American Journal of Surgical Pathology. 26 (9): 1175-1183. doi:10.1097/00000478-200209000 ...
https://en.wikipedia.org/wiki/Rhabdomyosarcoma
Mesenchymal Chondrosarcoma in Children and Young Adults: A Single Institution Retrospective ReviewMesenchymal Chondrosarcoma in Children and Young Adults: A Single Institution Retrospective Review
... Michael W. Bishop,1,2 ... Mesenchymal chondrosarcoma is an aggressive, uncommon histologic entity arising in bone and soft tissues. We reviewed our ... We conducted a retrospective chart review on patients with mesenchymal chondrosarcoma over a 24-year period. Clinicopathologic ... Aggressive surgical resection of mesenchymal chondrosarcoma with chemoradiotherapy yields excellent local control and may ...
https://www.hindawi.com/journals/sarcoma/2015/608279/abs/
Metastatic mesenchymal chondrosarcomaMetastatic mesenchymal chondrosarcoma
Extraskeletal mesenchymal chondrosarcoma. Radiology 1993;186:819-26. [ Links ]. 13. Aryoshi Y, Shimahara M. Mesenchymal ... It has also been established that mesenchymal chondrosarcoma expresses Sox-9 gene, a regulator in mesenchymal cell ... Mesenchymal chondrosarcoma of the jaws. Oral Surg Oral Md Oral Pathol 1982;54:197-206. [ Links ]. ... Mesenchymal chondrosarcoma of bone and soft tissue. A review of 111 cases. Cancer 1986;57:2444-453. [ Links ]. ...
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1681-150X2010000200013&lng=pt&nrm=iso
Extraskeletal mesenchymal chondrosarcoma of the thighExtraskeletal mesenchymal chondrosarcoma of the thigh
Pathologically, the main difference between extraskeletal myxoid chondrosarcoma and extraskeletal mesenchymal chondrosarcoma is ... and Dowling reported the first case of an extraskeletal mesenchymal chondrosarcoma in 1964.8,9 Extraskeletal mesenchymal ... Mesenchymal chondrosarcoma. J Bone Joint Surg Am. 1964;46:. 747. -754.. * Lightenstein L, Bernstein D. Unusual benign and ... Extraskeletal mesenchymal chondrosarcoma is a rare form of sarcoma that is not connected to bone, but typically involves the ...
https://www.hcplive.com/view/2007-06_06
Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon...Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon...
Identification of the novel HEY1-NCOA2 fusion in the mesenchymal chondrosarcoma case UF5. A, Upper: partial schema of HEY1 and ... RT-PCR detection of the HEY1-NCOA2 fusion in additional mesenchymal chondrosarcoma cases. Upper panel: RT-PCR performed using ... Exon expression plot of NCOA2 in the mesenchymal chondrosarcoma sample UF5, showing the intragenic change in NCOA2 expression. ... Interphase FISH detection of HEY1-NCOA2 fusion in mesenchymal chondrosarcomas. A, the schema of FISH-probe design. B, ...
https://www.ncbi.nlm.nih.gov/pubmed/22034177
Response to: Periosteal mesenchymal chondrosarcoma of the tibia | Springer for Research & DevelopmentResponse to: Periosteal mesenchymal chondrosarcoma of the tibia | Springer for Research & Development
Khalil and colleagues for their comments [1]. We agree that the discovery of the fusion testing in mesenchymal chondrosarcoma ... Periosteal mesenchymal chondrosarcoma of the tibia. Skeletal Radiol. https://doi.org/10.1007/s00256-018-2885-9. ... It is true that molecular testing with its increasing availability now can be helpful in establishing diagnosis of mesenchymal ... chondrosarcomas, particularly those with less than optimal pathologic features or sampling. We intend to make use of testing ...
https://rd.springer.com/article/10.1007/s00256-018-2914-8
Mesenchymal chondrosarcoma of maxilla in paediatric patient | BMJ Case ReportsMesenchymal chondrosarcoma of maxilla in paediatric patient | BMJ Case Reports
Mesenchymal chondrosarcoma (MCS) is a rare subtype of CS that is more aggressive and may lead to erroneous diagnosis in a ... Chondrosarcoma (CS) is a malignant tumour of long and flat bone characterised by the formation of cartilage. ...
https://casereports.bmj.com/content/12/3/e228969
Orbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis | springermedizin.atOrbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis | springermedizin.at
Mesenchymal chondrosarcoma of the orbit: CT and MRI Findings. Clin Radiol. 2012;67:346-51. CrossRefPubMed ... Mesenchymal chondrosarcoma of the orbit: CT and MRI Findings. Clin Radiol. 2012;67:346-51. CrossRefPubMed Yang BT, Wang YZ, ... Radiological features and pathology of extraskeletal mesenchymal chondrosarcoma. Clin Imaging. 2012;36:365-70. CrossRefPubMed ... Orbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis. Case report and review of the ...
https://www.springermedizin.at/orbito-maxillofacial-mesenchymal-chondrosarcoma-with-intracrania/14930916?fulltextView=true
Molecular Testing for Mesenchymal ChondrosarcomaMolecular Testing for Mesenchymal Chondrosarcoma
Learn in-depth information on Molecular Testing for Mesenchymal Chondrosarcoma, on why the laboratory test is performed, ... Test for Molecular Diagnosis of Mesenchymal Chondrosarcoma. What is Molecular Testing for Mesenchymal Chondrosarcoma? ( ... Molecular Testing for Mesenchymal Chondrosarcoma is a genetic test that is helpful in aiding a diagnosis of mesenchymal ... Molecular Testing for Mesenchymal Chondrosarcoma is a genetic test that is helpful in aiding a diagnosis of mesenchymal ...
https://www.dovemed.com/common-procedures/procedures-laboratory/molecular-testing-mesenchymal-chondrosarcoma/
Chondrosarcoma, Mesenchymal - Semantic ScholarChondrosarcoma, Mesenchymal - Semantic Scholar
Mesenchymal chondrosarcomas have a predilection for flat bones; long tubular bones are rarely affected. They tend to occur in ... A rare aggressive variant of chondrosarcoma, characterized by a biphasic histologic pattern of small compact cells intermixed ... Chondrosarcoma, Mesenchymal. Known as: Chondrosarcomas, Mesenchymal, chondrosarcoma mesenchymal, Mesenchymal Chondrosarcoma ( ... Chondrosarcoma with additional mesenchymal component (dedifferentiated chondrosarcoma). I. A clinicopathologic study of 26 ...
https://www.semanticscholar.org/topic/Chondrosarcoma%2C-Mesenchymal/141503
Chondrosarcoma: Practice Essentials, Background, PathophysiologyChondrosarcoma: Practice Essentials, Background, Pathophysiology
Chondrosarcoma is a collective term for a group of tumors that consist predominantly of cartilage and that range from low-grade ... Mesenchymal chondrosarcoma. The 5-year survival rate for mesenchymal chondrosarcoma is less than 50%, with an overall 10-year ... Fewer than 2% of all chondrosarcomas are mesenchymal chondrosarcomas. The maxilla and the mandible are the most common sites of ... encoded search term (Chondrosarcoma) and Chondrosarcoma What to Read Next on Medscape. Related Conditions and Diseases. * Fast ...
https://emedicine.medscape.com/article/1258236-overview
Mesenchymal chondrosarcoma - Libre PathologyMesenchymal chondrosarcoma - Libre Pathology
Chondrosarcoma.. References. *↑ Dowling EA (June 1964). "Mesenchymal chondrosarcoma". J Bone Joint Surg Am 46: 747-54. PMID ... Mesenchymal chondrosarcoma is a rare type of chondrosarcoma that is found in the soft tissue. ... Jun 2011). "[Clinicopathologic and immunohistochemical study of 23 cases of mesenchymal chondrosarcoma].". Zhonghua Bing Li Xue ... May 2010). "Reappraisal of mesenchymal chondrosarcoma: novel morphologic observations of the hyaline cartilage and endochondral ...
https://librepathology.org/wiki/Mesenchymal_chondrosarcoma
Mesenchymal Chondrosarcoma : Tumors of the boneMesenchymal Chondrosarcoma : Tumors of the bone
Radiation is used in selected cases, particularly extraskeletal mesenchymal chondrosarcomas. *Wide/Radical limb sparing surgery ... Thank-you so very much for being my surgeon for that chondrosarcoma, for saving my life! And I have learned over the months ( ... Undifferentiated mesenchymal cells similar to Ewing sarcoma. *Low grade islands of cartilage scattered throughout the ...
http://www.tumorsurgery.org/tumor-education/bone-tumors/types-of-bone-tumors/mesenchymal-chondrosarcoma.aspx
Mesenchymal chondrosarcoma of maxilla : a rare case reportMesenchymal chondrosarcoma of maxilla : a rare case report
Mesenchymal chondrosarcoma (MC) is a rare variant of chondrosarcoma (CS) that accounts for upto 3-9% of all CS and has high ... Mesenchymal chondrosarcoma of maxilla : a rare case report. DSpace Repository. Valencià Castellano ... Mesenchymal chondrosarcoma of maxilla : a rare case report. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 16 ... Mesenchymal chondrosarcoma of maxilla : a rare case report. Show simple item record ...
http://roderic.uv.es/handle/10550/60114?show=full
Trisomy 8 as the sole cytogenetic abnormality in a case of extraskeletal mesenchymal chondrosarcoma<...Trisomy 8 as the sole cytogenetic abnormality in a case of extraskeletal mesenchymal chondrosarcoma<...
Some mesenchymal chondrosarcomas have a t(11;22) translocation suggesting a relationship with the PNET/Ewing tumor family. We ... Trisomy 8 as the sole cytogenetic abnormality in a case of extraskeletal mesenchymal chondrosarcoma. / Gatter, Ken M.; Olson, ... Some mesenchymal chondrosarcomas have a t(11;22) translocation suggesting a relationship with the PNET/Ewing tumor family. We ... N2 - Mesenchymal chondrosarcoma is a rare malignant tumor that comprises about 3-10% of all sarcomas. Reports of cytogenetic ...
https://ohsu.pure.elsevier.com/en/publications/trisomy-8-as-the-sole-cytogenetic-abnormality-in-a-case-of-extras-2
Intracranial extraskeletal mesenchymal chondrosarcoma: Case report<...Intracranial extraskeletal mesenchymal chondrosarcoma: Case report<...
Intracranial extraskeletal mesenchymal chondrosarcoma: Case report. Together they form a unique fingerprint. * Mesenchymal ... Intracranial extraskeletal mesenchymal chondrosarcoma: Case report. Kimberly D. Bingaman, Cargill H. Alleyne, Jeffrey J. Olson ... CONCLUSION: Intracranial mesenchymal chondrosarcoma is a rare neoplasm that can mimic a meningioma radiographically. We present ... CONCLUSION: Intracranial mesenchymal chondrosarcoma is a rare neoplasm that can mimic a meningioma radiographically. We present ...
https://augusta.pure.elsevier.com/en/publications/intracranial-extraskeletal-mesenchymal-chondrosarcoma-case-report
Soft Tissue Sarcoma | Vanderbilt-Ingram Cancer CenterSoft Tissue Sarcoma | Vanderbilt-Ingram Cancer Center
Extraskeletal mesenchymal chondrosarcoma. Treatment of extraskeletal mesenchymal chondrosarcoma may include the following: * ... Extraskeletal mesenchymal chondrosarcoma . This type of bone and cartilage tumor often affects young adults and occurs in the ... Extraskeletal myxoid chondrosarcoma. Treatment of extraskeletal myxoid chondrosarcoma may include the following:. * Surgery to ... Extraskeletal myxoid chondrosarcoma . This type of soft tissue sarcoma may occur in children and adolescents. Over time, it ...
https://www.vicc.org/cancer-info/childhood-soft-tissue-sarcoma
January/February 2012 - Volume 17 - Issue 1 : AJSP: Reviews & ReportsJanuary/February 2012 - Volume 17 - Issue 1 : AJSP: Reviews & Reports
Mesenchymal Chondrosarcoma of the Chest Wall. Borys, Dariusz; Canter, Robert J. Borys, Dariusz; Canter, Robert J. Less ...
http://journals.lww.com/pathologycasereviews/toc/2012/01000
Primary extraskeletal mesenchymal chondrosarcoma of the vulva | Obstetrics & Gynecology Science;: 345-348, 2013. | WPRIMPrimary extraskeletal mesenchymal chondrosarcoma of the vulva | Obstetrics & Gynecology Science;: 345-348, 2013. | WPRIM
Full text: Available Index: WPRIM (Western Pacific) Main subject: Vulva / Humans / Chondrosarcoma / Chondrosarcoma, Mesenchymal ... Full text: Available Index: WPRIM (Western Pacific) Main subject: Vulva / Humans / Chondrosarcoma / Chondrosarcoma, Mesenchymal ... The final pathological reports confirmed extraskeletal mesenchymal chondrosarcoma (EMC) of the vulva revealing no microscopic ... Extraskeletal chondrosarcoma is rare, making up only 1% of reported chondrosarcoma. We experienced 3 cases of extraskeletal ...
https://search.bvsalud.org/gim/resource/en/wpr-175329
Extraskeletal Mesenchymal Chondrosarcoma of Shoulder: An Extremely Rare Case | Journal of Orthopaedic Case ReportsExtraskeletal Mesenchymal Chondrosarcoma of Shoulder: An Extremely Rare Case | Journal of Orthopaedic Case Reports
Overall, mesenchymal chondrosarcomas included less than 10% of all type of chondrosarcomas and often originates from the ... You are at:Home » Sep - Oct 2016 , Volume 6 , Issue 4 » Extraskeletal Mesenchymal Chondrosarcoma of Shoulder: An Extremely Rare ... Mesenchymal chondrosarcoma of bone and soft tissues. Cancer. 1983;52:533-541.. 4. Seo C, Jung S T, Byun J W. Extraskeletal ... Extraskeletal mesenchymal chondrosarcoma of the forearm: a case report. J Hand Surg Am. 2007;32:389-392.. 3. Bertoni F, Picci P ...
http://test.jocr.co.in/2016/10/10/2250-0685-560-fulltext/
Radiological features of extraskeletai mesenchymal chondrosarcoma | Chinese Journal of Radiology;(12): 248-251, 2012. | WPRIMRadiological features of extraskeletai mesenchymal chondrosarcoma | Chinese Journal of Radiology;(12): 248-251, 2012. | WPRIM
Radiological features of extraskeletai mesenchymal chondrosarcoma Radiological features of extraskeletai mesenchymal ... Objective To explore CT,MRI findings of extraskeletal mesenchymal chondrosarcoma (EMC).Methods Imaging information of all 8 ...
https://search.bvsalud.org/gim/resource/en/wpr-425169
Regulation of onco and tumor suppressor MiRNAs by mTORC1 inhibitor PRP-1 in human chondrosarcoma | SpringerLinkRegulation of onco and tumor suppressor MiRNAs by mTORC1 inhibitor PRP-1 in human chondrosarcoma | SpringerLink
Metastatic chondrosarcoma of mesenchymal origin is the second most common bone malignancy and does not respond either to ... Metastatic chondrosarcoma of mesenchymal origin is the second most common bone malignancy and does not respond either to ... PRP-1 inhibits mesenchymal tumors. Tumour Biol. 2011;32(4):745-51.PubMedCrossRefGoogle Scholar ... Kinome profiling of chondrosarcoma reveals Src-pathway activity and dasatinib as option for treatment. Cancer Res. 2009;69:6216 ...
https://link.springer.com/article/10.1007/s13277-013-1309-7
Coexistence of Extraskeletal Mesenchymal Chondrosarcoma and Isolated Hemihyperplasia: A Case Report | Journal of Orthopaedic...Coexistence of Extraskeletal Mesenchymal Chondrosarcoma and Isolated Hemihyperplasia: A Case Report | Journal of Orthopaedic...
However no such concomitance has been reported with chondrosarcoma. We report the first case of mesenchymal chondrosarcoma ... Immunohistochemical and morphological findings revealed malignant mesenchymal chondrosarcoma. Conclusion: IH is well known to ... results of surgery depending on location or extension to unresectable sites of majority of mesenchymal chondrosarcomas. ... But no such association has been reported with chondrosarcoma. In musculoskeletal masses of patients with hemihyperplasia, the ...
http://www.jocr.co.in/wp/2016/04/01/2250-0685-416-fulltext/
Chondrosarcoma facts, information, pictures | Encyclopedia.com articles about ChondrosarcomaChondrosarcoma facts, information, pictures | Encyclopedia.com articles about Chondrosarcoma
Make research projects and school reports about Chondrosarcoma easy with credible articles from our FREE, online encyclopedia ... clear cell chondrosarcoma, mesenchymal chondrosarcoma, and dedifferentiated chondrosarcoma. Clear cell chondrosarcoma is the ... Central chondrosarcoma and peripheral chondrosarcoma are both classic chondrosarcomas. Central chondrosarcoma occurs within a ... Mesenchymal chondrosarcoma is another rare variant. However, as opposed to clear cell chondrosarcoma, it is highly malignant ...
http://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/chondrosarcoma
Global Chondrosarcoma Market Report 2017 Estimated To Grow Worldwide By 2022: Global QYResearch | MedgadgetGlobal Chondrosarcoma Market Report 2017 Estimated To Grow Worldwide By 2022: Global QYResearch | Medgadget
This report studies Global Chondrosarcoma Market, especially in North America, China, Europe, Southeast Asia, Japan and India, ... Conventional Chondrosarcoma. Clear Cell Chondrosarcoma. Myxoid Chondrosarcoma. Mesenchymal Chondrosarcoma. Dedifferentiated ... 1.2.4 Mesenchymal Chondrosarcoma. 1.2.5 Dedifferentiated Chondrosarcoma. 1.2.6 Others. 1.3 Applications of Chondrosarcoma. 1.3. ... 6.3.3 Myxoid Chondrosarcoma of Chondrosarcoma Growth Driving Factor Analysis. 6.3.4 Mesenchymal Chondrosarcoma of ...
https://www.medgadget.com/2017/12/global-chondrosarcoma-market-report-2017-estimated-to-grow-worldwide-by-2022-global-qyresearch.html
Images & Histologies of Extraskeletal Mesenchymal Chondrosarcoma | Sarcoma Images | A Descriptive Image Database of Bone & Soft...Images & Histologies of Extraskeletal Mesenchymal Chondrosarcoma | Sarcoma Images | A Descriptive Image Database of Bone & Soft...
High-Resoultion Images of Extraskeletal Mesenchymal Chondrosarcoma from Sarcoma Images, the Internet Database of Bone and Soft ...
http://www.sarcomaimages.com/index.php?v=Extraskeletal-Mesenchymal-Chondrosarcoma
Bone Sarcomas | Johns Hopkins MedicineBone Sarcomas | Johns Hopkins Medicine
Mesenchymal chondrosarcoma. * Neurofibroma of bone (schwannoma). * Osteoblastoma. * Pagets disease/pagetoid osteosarcoma. * ...
https://www.hopkinsmedicine.org/health/conditions-and-diseases/sarcoma/bone-sarcomas
Diagnostic Radiology/Musculoskeletal Imaging/Tumors Advanced - Wikibooks, open books for an open worldDiagnostic Radiology/Musculoskeletal Imaging/Tumors Advanced - Wikibooks, open books for an open world
1. Cartilaginous a. Mesenchymal chondrosarcoma 2. Osseous a. High grade surface osteosarcoma 3. Fibrous and fibrohistiocytic a ...
https://en.wikibooks.org/wiki/Diagnostic_Radiology/Musculoskeletal_Imaging/Tumors_Advanced
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With...Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With...
Mesenchymal (extraskeletal) chondrosarcoma. *Leiomyosarcoma. *Liposarcoma (excluding myxoid liposarcoma). *Undifferentiated ... extraskeletal myxoid chondrosarcoma, neoplasms with perivascular epithelioid cell differentiation (PEComa), intimal sarcoma, ... atypical fibroxanthoma, mixed tumor NOS, phosphaturic mesenchymal tumor, malignant ossifying fibromyxoid tumor, malignant mixed ...
https://clinicaltrials.gov/ct2/show/record/NCT02180867?show_locs=Y
Mesenchymal Chondrosarcoma of the Sinonasal Cavity: A Case Report and by Kevin P. Banks, Justin Q. Ly et al."Mesenchymal Chondrosarcoma of the Sinonasal Cavity: A Case Report and " by Kevin P. Banks, Justin Q. Ly et al.
Histologically, mesenchymal chondrosarcomas are characterized by a mix of cartilage and undifferentiated stromal tissue. ... We present a case of mesenchymal chondrosarcoma presenting as chronic sinusitis, arising in the sinonasal cavity. Additionally ... Radiographically, they demonstrate features similar to the more commonly encountered conventional chondrosarcoma, with the ... Mesenchymal chondrosarcoma is a rare, highly malignant cartilaginous forming tumor that is rarely encountered in clinical ...
https://corescholar.libraries.wright.edu/surg/454/
TumorsTumorExtraskeletal mesenchymalOsteosarcomaClear cell chondrosarcomaCase of mesenchymal chondrosarcomaMetastaticClassic features of mesenchymal chondrosarcomaType of chondrosarcomaHigh grade chondrosarcomaAggressivePatients with mesenchymal chondrosarcomaIntracranialFusion in mesenchymal chondrosarcomaHistologicBenignAdditional mesenchymal componentNeoplasmCentral chondrosarcomaDiagnosis of mesenchymalSubtypesChemotherapyApoptosis in human chondrosarcomaFibrosarcomaHuman chondrosarcoma cellsSoft tissuePrognosisConclusionSubtypePeriostealMaxillaDifferentiationHighly malignant variantMyxoid ChondrosarcomaPrimary chondrosarcomasLesionsHistologicalTypes of chondrosarcomaAtypicalSecondarySpindleYoung AdultsFibrousTreat chondrosarcomaCD99VariantOccurPelvisCarcinoma
Tumors21
  • 1 Malignant cartilaginous tumors that are not connected to bone are called extraskeletal chondrosarcomas. (hcplive.com)
  • 8,9 Extraskeletal mesenchymal chondrosarcomas are extremely rare, fully malignant tumors with an obscure etiology. (hcplive.com)
  • In general, chondrosarcomas are malignant tumors that mostly arise in the bone. (dovemed.com)
  • Sox9, a master regulator of chondrogenesis, distinguishes mesenchymal chondrosarcoma from other small blue round cell tumors. (semanticscholar.org)
  • Chondrosarcoma is a collective term for a group of tumors that consist predominantly of cartilage and that range from low-grade tumors with low metastatic potential to high-grade, aggressive tumors characterized by early metastasis. (medscape.com)
  • PRP-1 inhibits mesenchymal tumors. (springer.com)
  • Due to the location of chondrosarcoma tumors, the result is often a decrease in the range of motion of limbs, especially tumors occurring on the epiphysis of bones such as those seen in clear cell chondrosarcoma. (encyclopedia.com)
  • However, researchers have discovered that chondrosarcomas are sometimes associated with underlying benign bone tumors. (encyclopedia.com)
  • Moreover, in vivo chondrosarcoma xenograft study revealed a dramatic reduction in tumor volume and the increased SIRT1 and cleaved caspase-3 expressions in tumors by resveratrol treatment. (nature.com)
  • Chondrosarcoma is one of the most common primary bone tumors ranking after myeloma and osteosarcoma, accounting for approximately 20% of bone sarcomas and may occur at any age between 10 and 80 years 1 . (nature.com)
  • Peripheral de-differentiated chondrosarcomas are among the rarest malignant mesenchymal tumors. (hindawi.com)
  • This investigation surveyed imaging of peripheral de-differentiated chondrosarcomas to facilitate better recognition of these uncommon tumors. (hindawi.com)
  • Chondrosarcoma represents a heterogeneous group of cartilage-forming tumors. (aacrjournals.org)
  • These tumors are treated by en bloc resection. (aacrjournals.org)
  • Saglik, "Secondary chondrosarcoma in cartilage bone tumors: report of 32 patients," Journal of Orthopaedic Science, vol. (thefreedictionary.com)
  • Background: Sarcomas are rare tumors (1-2% of all cancers) of mesenchymal origin that may develop in soft tissues and viscera. (ebscohost.com)
  • Analyzes the clinicoradiographic, microscopic and immunophenotypic features of 21 tumors from 13 patients with mesenchymal chondrosarcoma neoplasms. (ebscohost.com)
  • FAS-positive sarcomas were found in 13 of 23 malignant fibrous histiocytomas, 3 of 17 liposarcomas, 3 of 7 malignant peripheral nerve sheath tumors, and 1 extraskeletal mesenchymal chondrosarcoma. (aacrjournals.org)
  • The gene was originally identified because of its amplification in a human glioblastoma, and previous studies have shown it to be amplified in a significant proportion of mesenchymal tumors, such as childhood sarcomas. (aacrjournals.org)
  • Samples from 40 patients (37 sarcomas and 3 benign mesen chymal tumors) and samples of 15 normal mesenchymal tissues were examined for GLI gene amplification and expression by Southern hybridization, reverse transcription-PCR of tissue RNA, and immunohisto- chemistry, using a new polyclonal GLI antibody developed against an epitope outside of the zinc finger region. (aacrjournals.org)
  • A chondrosarcoma is a member of a category of tumors of bone and soft tissue known as sarcomas. (wikipedia.org)
Tumor33
  • The patient underwent tumor resection and a biopsy confirmed the presence of a mesenchymal chondrosarcoma. (springermedizin.at)
  • Mesenchymal chondrosarcoma is a rare malignant tumor that comprises about 3-10% of all sarcomas. (elsevier.com)
  • Some mesenchymal chondrosarcomas have a t(11;22) translocation suggesting a relationship with the PNET/Ewing tumor family. (elsevier.com)
  • Extraskeletal chondrosarcoma is a rare tumor which originates in the soft tissue compartment and is classified as myxoid and mesenchymal based on histologic criteria. (jocr.co.in)
  • Chondrosarcoma is a malignant tumor that arises from cells that produce cartilage, the rubbery tissue around joints. (encyclopedia.com)
  • Depending on the type and location of the chondrosarcoma, the tumor can either be high grade and aggressive or low grade and not as invasive. (encyclopedia.com)
  • Mesenchymal chondrosarcoma is a malignant tumor which originates from chondrogenic tissue. (jocr.co.in)
  • chondrosarcoma, hemihyperplasia, mesenchymal tumor. (jocr.co.in)
  • Mesenchymal chondrosarcoma is a rare, highly malignant cartilaginous forming tumor that is rarely encountered in clinical practice. (wright.edu)
  • Radiographically, they demonstrate features similar to the more commonly encountered conventional chondrosarcoma, with the tumor location and patient age helping to suggest the correct diagnosis. (wright.edu)
  • Chondrosarcoma is a malignant primary bone tumor. (nature.com)
  • Here, we investigated the role of SIRT1 induction by resveratrol in human chondrosarcoma cell growth and tumor progression. (nature.com)
  • Primary mesenchymal chondrosarcoma of the kidney is rare, and it shows distinct undifferentiated tumor cells and well differentiated cartilagenous components. (biomedcentral.com)
  • The imaging characteristics described for central de-differentiated chondrosarcomas are similar to the peripheral form of this tumor. (hindawi.com)
  • Dedifferentiation to leiomyosarcoma, giant cell tumor , and rarely, clear-cell chondrosarcoma or rhabdomyosarcoma has been reported. (atlasgeneticsoncology.org)
  • Chondrosarcoma is a malignant cartilage forming bone tumor, in which mutations altering isocitrate dehydrogenase-1 and -2 (IDH1 and IDH2) activity have been identified as potential driver mutations. (aacrjournals.org)
  • The far most prevalent subtype (72% of the cases) is conventional central chondrosarcoma, in which the tumor arises centrally in the medulla of the bone. (aacrjournals.org)
  • This subtype can be histologically subdivided into atypical cartilaginous tumor (ACT), grade II and grade III chondrosarcomas. (aacrjournals.org)
  • Chondrosarcoma patients with unresectable disease, due to tumor location, tumor size, or extensive metastatic disease, have a 5-year survival of only 2% as the overall efficacy of chemotherapy is limited ( 8, 9 ). (aacrjournals.org)
  • Mesenchymal chondrosarcoma (MCHS) is a highly aggressive, malignant, cartilaginous tumor that represents about 1% of all chondrosarcomas. (entjournal.com)
  • Possible signs of chondrosarcoma include pain and swelling near the tumor. (pennmedicine.org)
  • The malignant cartilage bone tumor is called chondrosarcoma. (lumc.nl)
  • Insulin increases synthesis of mucopolysaccharides in the chondrocytes whereas it elevates synthesis of proteoglycans in the tumor cells obtained from the chondrosarcoma cells. (thefreedictionary.com)
  • Chondrosarcoma is a malignant mesenchymal tumor that produces cartilaginous matrix. (thefreedictionary.com)
  • Soft tissue sarcomas, such as leiomyosarcoma , chondrosarcoma , and gastrointestinal stromal tumor (GIST) , are more common in adults than in children. (wikidoc.org)
  • Intranodal palisaded myofibroblastoma (IPM) also called as intranodal hemorrhagic spindle cell tumor with amianthoid fibers is a distinctive and rare mesenchymal neoplasm of lymph nodes. (biomedsearch.com)
  • Conventional chondrosarcoma can be a difficult tumor to treat. (sarctrials.org)
  • Grade 1 chondrosarcomas almost never metastasize and are now called "atypical cartilaginous tumor", Grade 2 chondrosarcomas have only a 10-15% risk of metastasis, and grade 3 chondrosarcomas have a two-thirds or higher risk of metastasis. (sarctrials.org)
  • It shows features of both chondrosarcoma and a less differentiated tumor, such as UPS (undifferentiated pleomorphic sarcoma), which does not show even a hint of relatedness to the chondrosarcoma. (sarctrials.org)
  • This rare bone tumor shows a mixture of aggressive small round blue cells mixed with more typical lower-grade chondrosarcoma. (sarctrials.org)
  • In addition to confirming the importance of GLI in mesenchymal differentiation, the data suggest a relationship between GLI gene expression and tumor grade. (aacrjournals.org)
  • Specimens from 40 patients were used in this study [37 samples of bone and soft tissue sarcomas of various histological types (MPNST, leiomyosarcomas, liposarcomas, osteosarcomas, chondrosarcomas, MFH, and others) and 3 samples of mesenchymal benign neoplasias] as well as 15 samples of normal mesenchymal tissues originating from those tumor excisions. (aacrjournals.org)
  • Musculoskeletal tumor specialists or orthopedic oncologists are usually chosen to treat chondrosarcoma, unless it is located in the skull, spine, or chest cavity, in which case, a neurosurgeon or thoracic surgeon experienced with sarcomas is chosen. (wikipedia.org)
Extraskeletal mesenchymal10
  • Microscopic evaluation revealed a biomorphic pattern composed of undifferentiated round or oval cells resembling embryonal mesenchyme and well-differentiated cartilaginous tissue, which is a characteristic finding of extraskeletal mesenchymal chondrosarcoma (Figure 4). (hcplive.com)
  • Lightenstein and Bernstein first described mesenchymal chondrosarcomas in 1959, and Dowling reported the first case of an extraskeletal mesenchymal chondrosarcoma in 1964. (hcplive.com)
  • Extraskeletal mesenchymal chondrosarcomas involve muscles or the central nervous system. (hcplive.com)
  • Extraskeletal mesenchymal chondrosarcoma. (semanticscholar.org)
  • OBJECTIVE AND IMPORTANCE: We present a patient with a dural-based intracranial extraskeletal mesenchymal chondrosarcoma, which was initially thought to be an atypical meningioma. (elsevier.com)
  • Pathological examination revealed an extraskeletal mesenchymal chondrosarcoma. (elsevier.com)
  • The final pathological reports confirmed extraskeletal mesenchymal chondrosarcoma (EMC) of the vulva revealing no microscopic lesions on the resection margins . (bvsalud.org)
  • Objective To explore CT,MRI findings of extraskeletal mesenchymal chondrosarcoma (EMC). (bvsalud.org)
  • Management of renal extraskeletal mesenchymal chondrosarcoma. (springer.com)
  • Extraskeletal mesenchymal chondrosarcoma is rare, and uaually arises in the head and neck region, followed by the lower extremity, the trunk and the retroperitoneum. (biomedcentral.com)
Osteosarcoma9
  • There are three main types of bone sarcoma based on tissue type - an osteosarcoma, a Ewing's sarcoma, and a chondrosarcoma. (wikipedia.org)
  • Subtypes of chondrosarcomas have different features and different outlooks, they include:[citation needed] Dedifferentiated Dedifferentiated chondrosarcomas can change in part to cells that are like those of an osteosarcoma for example which has a faster rate of growth. (wikipedia.org)
  • A dedifferentiated chondrosarcoma tumour is treated like an osteosarcoma tumour because it is a more aggressive type of chondrosarcoma. (cancer.ca)
  • Dedifferentiated chondrosarcoma may be treated with some of the same chemotherapy drugs that are used for osteosarcoma . (cancer.ca)
  • The non-cartilaginous component of dedifferentiated chondrosarcoma is generally an osteosarcoma , a fibrosarcoma, or a malignant fibrous histiocytoma. (atlasgeneticsoncology.org)
  • With patients who present with locally advanced or metastatic chondrosarcoma, chordoma, or osteosarcoma, physicians should discuss the options surrounding deep-sequencing genomic tests, which may identify mutations that may be responsive to specific therapies and thus may guide referral to clinical trials. (medscape.com)
  • Rare primary bone malignancies such as clear cell chondrosarcoma and giant cell rich osteosarcoma can also mimic GCTB but often have more destructive features, adjacent bone marrow edema, and/or a soft tissue mass component. (thefreedictionary.com)
  • For example, osteosarcoma arises from bone , chondrosarcoma arises from cartilage , and leiomyosarcoma arises from smooth muscle . (wikidoc.org)
  • Patients with the following types of bone sarcoma: Ewing sarcoma, osteosarcoma, and chondrosarcoma [de-differentiated or mesenchymal]. (clinicaltrials.gov)
Clear cell chondrosarcoma6
  • There are three variant chondrosarcomas: clear cell chondrosarcoma, mesenchymal chondrosarcoma, and dedifferentiated chondrosarcoma. (encyclopedia.com)
  • Clear cell chondrosarcoma is the most rare form of chondrosarcoma. (encyclopedia.com)
  • However, as opposed to clear cell chondrosarcoma, it is highly malignant and frequently metastasizes, commonly to the lungs, lymph nodes and other bones. (encyclopedia.com)
  • Four histological subtypes of chondrosarcoma are described as peripheral-, dedifferentiated-, mesenchymal- and clear cell chondrosarcoma. (lumc.nl)
  • Clear cell chondrosarcoma of bone: a report of 8 cases. (thefreedictionary.com)
  • A version of chondrosarcoma called clear-cell chondrosarcoma has an intermediate risk of metastasis, but treatment is typically surgery alone. (sarctrials.org)
Case of mesenchymal chondrosarcoma5
  • We report the first case of mesenchymal chondrosarcoma presenting with isolated hemihypertrophy. (jocr.co.in)
  • We report a case of mesenchymal chondrosarcoma arising from the left ankle region of a patient with isolated hemihypertrophy of right side of her body. (jocr.co.in)
  • We present a case of mesenchymal chondrosarcoma presenting as chronic sinusitis, arising in the sinonasal cavity. (wright.edu)
  • We describe a rare case of mesenchymal chondrosarcoma of the thyroid gland with uncertain primary origin. (biomedcentral.com)
  • We report another case of mesenchymal chondrosarcoma of the kidney with synchronous implant and a coexistent infiltrating urothelial carcinoma of the ureter firstly. (biomedcentral.com)
Metastatic2
  • Both primary and metastatic mesenchymal chondrosarcoma found in the thyroid gland are extremely rare. (biomedcentral.com)
  • Dedifferentiated chondrosarcoma accounts for approximately 10% of all chondrosarcomas and shows an increased growth rate and rapid metastatic spread in comparison with ordinary chondrosarcomas. (atlasgeneticsoncology.org)
Classic features of mesenchymal chondrosarcoma2
  • Histopathological examination and immunohistochemical studuies showed the classic features of mesenchymal chondrosarcoma in kidney, as well as a few infiltrating urothelial in ureter. (biomedcentral.com)
  • However, the amount of these spindled cells is small and not all the classic features of mesenchymal chondrosarcoma are seen on histology. (radiopaedia.org)
Type of chondrosarcoma4
  • Mesenchymal chondrosarcoma is a rare type of chondrosarcoma that is found in the soft tissue . (librepathology.org)
  • As the name implies, cells biopsied from this type of chondrosarcoma appear clear with many large vacuoles. (encyclopedia.com)
  • Mesenchymal chondrosarcoma is an aggressive, high-grade type of chondrosarcoma. (cancer.ca)
  • Mesenchymal Chondrosarcoma is a malignant type of chondrosarcoma, or cancer of cartilage. (cancerandcareers.org)
High grade chondrosarcoma4
  • Galoian K, Temple TH, Galoyan A. Cytostatic effect of the hypothalamic cytokine PRP-1 is mediated by mTOR and cMyc inhibition in high grade chondrosarcoma. (springer.com)
  • however, the survival of high-grade chondrosarcoma patients is still poor after surgical therapy. (nature.com)
  • Final diagnosis: high-grade chondrosarcoma . (radiopaedia.org)
  • Recent studies have shown that induction of apoptosis in high-grade chondrosarcoma, both directly and by enhancement of response to chemotherapy and radiation, is a valid therapeutic strategy. (wikipedia.org)
Aggressive7
  • Mesenchymal chondrosarcoma is an aggressive, uncommon histologic entity arising in bone and soft tissues. (hindawi.com)
  • Aggressive surgical resection of mesenchymal chondrosarcoma with chemoradiotherapy yields excellent local control and may reduce likelihood of late recurrence. (hindawi.com)
  • Mesenchymal chondrosarcoma (MCS) is a rare subtype of CS that is more aggressive and may lead to erroneous diagnosis in a limited biopsy. (bmj.com)
  • Extraskeletal chondrosarcomas (EMC) is a rare aggressive neoplasm which has been seen in the soft tissue area. (jocr.co.in)
  • In type 1, the radiographic appearance is the same as for a central chondrosarcoma, with the addition of a region with very aggressive bone destruction. (atlasgeneticsoncology.org)
  • Two other subtypes with a worse prognosis are dedifferentiated chondrosarcoma, a highly malignant variant ( 4 ), and mesenchymal chondrosarcoma, a rare aggressive subtype in which distant metastasis can be identified even after 20 years ( 5-7 ). (aacrjournals.org)
  • This more aggressive version of chondrosarcoma typically occurs in adolescence and in people over age 60. (sarctrials.org)
Patients with mesenchymal chondrosarcoma1
  • We conducted a retrospective chart review on patients with mesenchymal chondrosarcoma over a 24-year period. (hindawi.com)
Intracranial3
  • Intracranial mesenchymal chondrosarcoma. (semanticscholar.org)
  • CONCLUSION: Intracranial mesenchymal chondrosarcoma is a rare neoplasm that can mimic a meningioma radiographically. (elsevier.com)
  • From these data we give an overview of the current diagnostic procedures and therapeutic options of intracranial chondrosarcoma. (bmj.com)
Fusion in mesenchymal chondrosarcoma1
  • Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data. (nih.gov)
Histologic4
  • RT-PCR or FISH evidence of this HEY1-NCOA2 fusion was present in all additional mesenchymal chondrosarcomas tested with a definitive histologic diagnosis and adequate material for analysis (n = 9) but was absent in 15 samples of other subtypes of chondrosarcomas. (nih.gov)
  • Performing a truly representative biopsy of a chondrosarcoma is challenging because the lesion is composed of areas that carry different histologic grades. (medscape.com)
  • This soft tissue sarcoma is classified to myxoid and mesenchymal based on histologic criteria. (jocr.co.in)
  • Chondrosarcoma patients, especially those of high histologic grade with lower expression and hypermethylation of NAPRT, may benefit from inhibition of the NAD synthesis pathway. (aacrjournals.org)
Benign2
  • Benign cartilage lesions can be difficult to differentiate from slow-growing, low-grade chondrosarcomas. (medscape.com)
  • Secondary chondrosarcoma can occur in a previously benign cartilaginous lesion. (medscape.com)
Additional mesenchymal component1
  • Chondrosarcoma with additional mesenchymal component (dedifferentiated chondrosarcoma). (semanticscholar.org)
Neoplasm2
  • 2 This neoplasm differs from other forms of chondrosarcoma in that the preponderance of occurrences are in young adults, generally those between the ages of 15 and 35 years, with a slightly higher incidence in women. (hcplive.com)
  • Mesenchymal Chondrosarcoma: A Small Cell Neoplasm with Polyphenotypic Differentiation. (ebscohost.com)
Central chondrosarcoma2
  • Central chondrosarcoma and peripheral chondrosarcoma are both classic chondrosarcomas. (encyclopedia.com)
  • Central chondrosarcoma occurs within a bone, and peripheral chondrosarcoma develops on the surface of a bone. (encyclopedia.com)
Diagnosis of mesenchymal2
  • It is true that molecular testing with its increasing availability now can be helpful in establishing diagnosis of mesenchymal chondrosarcomas, particularly those with less than optimal pathologic features or sampling. (springer.com)
  • Molecular Testing for Mesenchymal Chondrosarcoma is a genetic test that is helpful in aiding a diagnosis of mesenchymal chondrosarcoma. (dovemed.com)
Subtypes1
Chemotherapy6
  • complete wide resection of mesenchymal chondrosarcoma could be enough as an initial treatment and chemotherapy reserved for patients that have unresectable masses. (jocr.co.in)
  • Mesenchymal Mesenchymal chondrosarcomas can grow quickly but unlike other types may respond to radiotherapy, and chemotherapy. (wikipedia.org)
  • Due to its poor response to both radiotherapy and chemotherapy, the management of chondrosarcoma faces a complicated challenge 2 . (nature.com)
  • Chemotherapy is not used for low-grade chondrosarcoma because it has not been shown to help improve survival. (cancer.ca)
  • What's the best chemotherapy protocol for mesenchymal chondrosarcoma stage 1b? (healthtap.com)
  • As a result, some people with grade 3 chondrosarcomas are treated with adjuvant chemotherapy. (sarctrials.org)
Apoptosis in human chondrosarcoma2
  • However, it is scarcely reported that SDF-1-Gab1 pathway mediates proliferation and apoptosis in human chondrosarcoma (CS). (springer.com)
  • Resveratrol significantly decreased cell viability and induced cell apoptosis in human chondrosarcoma cells in a dose-dependent manner. (nature.com)
Fibrosarcoma1
  • Among the less common are chondrosarcoma, fibrosarcoma , and malignant fibrous histiocytoma , all of which arise from spindle cell neoplasms. (encyclopedia.com)
Human chondrosarcoma cells2
  • There is no report about the role of SIRT1 in the human chondrosarcoma cells. (nature.com)
  • Both siRNA-SIRT1 transfection and MS-275 significantly inhibited the resveratrol-induced caspase-3 cleavage and activity in human chondrosarcoma cells. (nature.com)
Soft tissue2
  • It is characterized by the presence of a mix of low-grade chondrosarcoma and has undergone malignant degeneration, producing a fully malignant soft tissue mass that is no longer identifiable as cartilage. (encyclopedia.com)
  • Peripheral mineralization with a bimorphic pattern on CT scan and the presence of a soft-tissue mass should be considered worrisome for a peripheral de-differentiated chondrosarcoma, particularly in the setting of multiple hereditary exostoses. (hindawi.com)
Prognosis1
  • The mesenchymal subtype has a poor prognosis. (jocr.co.in)
Conclusion1
  • In conclusion, this study identified NAMPT as a potential target for treatment of chondrosarcoma. (aacrjournals.org)
Subtype2
  • It is a subtype of chondrosarcoma, a term that includes a heterogeneous group of lesions with varied clinical behaviour and morphological features that share the common feature arising from ossified cartilage or cartilaginous rests. (scielo.org.za)
  • Generally, mesenchymal subtype included less than 10% of all types of chondrosarcomas and is more common in the bone [1-3]. (jocr.co.in)
Periosteal2
  • Khalil S, Al-Rahawan MG, Al-Rahawan MM. Periosteal mesenchymal chondrosarcoma of the tibia. (springer.com)
  • 2. Juxtacortical (Periosteal) Chondrosarcoma. (bokus.com)
Maxilla3
  • Chondrosarcoma of the maxilla: a case report and review of literature. (springermedizin.at)
  • Chondrosarcoma of the maxilla: report of two cases with different behaviours. (springermedizin.at)
  • Zurück zum Zitat Gawande M, Swastika N, Chaudhary M, Patil S. Chondrosarcoma of maxilla. (springermedizin.at)
Differentiation2
  • Mesenchymal chondrosarcoma is a rare entity originally described in the literature as a biphasic tumour consisting of spindle cell mesenchyme mixed with areas of chondroid differentiation. (scielo.org.za)
  • Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells. (semanticscholar.org)
Highly malignant variant1
  • Dedifferentiated chondrosarcoma is a highly malignant variant of chondrosarcoma. (semanticscholar.org)
Myxoid Chondrosarcoma3
  • Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene ma. (genecards.org)
  • Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. (genecards.org)
  • Diseases associated with TAF15 include Chondrosarcoma, Extraskeletal Myxoid and Myxoid Chondrosarcoma . (genecards.org)
Primary chondrosarcomas2
Lesions1
  • One such tumour, the chondrosarcoma, the most malignant cartilage tumour, represents 0.15% of all cranial space occupying lesions and 6% of all skull base tumours. (bmj.com)
Histological2
  • A left thyroid lobectomy was done and the histological features suggestive of mesenchymal chondrosarcoma (MC) were established. (scielo.org.za)
  • On histological examination 51% of tumours were classified as grade I, 11% grade II, 30% mesenchymal, and 8% myxoïd. (bmj.com)
Types of chondrosarcoma1
  • Surgery is the main treatment for most types of chondrosarcoma. (cancer.ca)
Atypical1
  • There is chondroid matrix, containing atypical chondrocytes, in keeping with a chondrosarcoma. (radiopaedia.org)
Secondary1
  • A small minority of secondary chondrosarcomas occur in patients with Maffucci syndrome and Ollier disease. (wikipedia.org)
Spindle3
  • Histologically, the tumour showed a biphasic pattern made up of solid areas of round and spindle-shaped mesenchymal cells interspersed with islands of well-differentiated cartilage. (scielo.org.za)
  • original magnification, 10x) shows abrupt transition between a low grade chondrosarcoma (left) and a high grade spindle cell sarcoma (right). (atlasgeneticsoncology.org)
  • The presence of CD99 positive spindle cells suggests mesenchymal chondrosarcoma . (radiopaedia.org)
Young Adults1
  • Teens and young adults are most prone to mesenchymal chondrosarcoma. (dovemed.com)
Fibrous1
  • Other less common types of bone cancer include: Chondrosarcoma (a cancer arising in cartilage cells, usually found in adults between ages 50-75, though the less common mesenchymal-chondrosarcoma is more frequent in younger patients), Malignant Fibrous Histiocytoma of bone (MFH), Chondoma (a rare low grade malignancy occuring mostly between ages 30 -70), and other rare tumours. (cancerindex.org)
Treat chondrosarcoma2
  • Limb-sparing surgery may be used to treat chondrosarcoma in the arm, leg and pelvis. (cancer.ca)
  • External beam radiation therapy may be used to treat chondrosarcoma that can't be removed with surgery. (cancer.ca)
CD992
  • The mesenchymal component often exhibits a haemangiopericytic pattern with multiple vascular spaces ( Figure 4 ).The tumour cells were immunohistochemically reactive for CD99 and negative for S100. (scielo.org.za)
  • CD99 reactivity in mesenchymal chondrosarcoma. (semanticscholar.org)
Variant4
  • Rare variant of chondrosarcoma . (librepathology.org)
  • There are two different categories of chondrosarcomas - classic chondrosarcomas and variant chondrosarcomas. (encyclopedia.com)
  • Mesenchymal chondrosarcoma is another rare variant. (encyclopedia.com)
  • Mesenchymal chondrosarcoma (MSC) is a rare variant of chondrosarcoma. (clinorthop.org)
Occur3
  • Although there are exceptions, chondrosarcomas occur mainly in older adults forty to sixty years old and typically occur more in men than in women. (encyclopedia.com)
  • Chondrosarcoma can occur in the arms, legs, or the trunk of the body. (pennmedicine.org)
  • Chondrosarcomas most often occur in males. (thefreedictionary.com)
Pelvis3
  • Most chondrosarcomas develop in the pelvis, legs or arms. (wikipedia.org)
  • It is used to treat a chondrosarcoma in the bones of the skull or spine, as well as in the arm, leg and pelvis. (cancer.ca)
  • Chondrosarcoma is considered as a common primary bone sarcoma, which is ranked as the third primary bone malignancy One in five cases of bone sarcomas are due to chondrosarcoma , and half of all cases affect the pelvis (1). (thefreedictionary.com)
Carcinoma3
  • We report a case of primary mesenchymal chondrosarcoma occurring in the left kidney with an ipsilateral and distinct distal ureteric implant, and a coexisting infiltrating urothelial carcinoma of the ureter in a 64-year-old man. (biomedcentral.com)
  • Multitarget fluorescence in situ hybridization (FISH) suggested that the development of the urothelial carcinoma in the ureter may be triggered or induced by the chondrosarcoma component. (biomedcentral.com)
  • This is the first reported case of a primary mesenchymal chondrosarcoma of the kidney with coexisting infiltrating urothelial carcinoma of the ureter. (biomedcentral.com)
Soft Tissue Sarcoma | Vanderbilt-Ingram Cancer Center
Soft Tissue Sarcoma | Vanderbilt-Ingram Cancer Center (vicc.org)
Extraskeletal mesenchymal chondrosarcoma of the thigh
Extraskeletal mesenchymal chondrosarcoma of the thigh (hcplive.com)
Bone Sarcomas | Johns Hopkins Medicine
Bone Sarcomas | Johns Hopkins Medicine (hopkinsmedicine.org)
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With...
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With... (clinicaltrials.gov)
Response to: Periosteal mesenchymal chondrosarcoma of the tibia | Springer for Research & Development
Response to: Periosteal mesenchymal chondrosarcoma of the tibia | Springer for Research & Development (rd.springer.com)
Global Chondrosarcoma Market Report 2017 Estimated To Grow Worldwide By 2022: Global QYResearch | Medgadget
Global Chondrosarcoma Market Report 2017 Estimated To Grow Worldwide By 2022: Global QYResearch | Medgadget (medgadget.com)
Gab1 regulates SDF-1-induced progression via inhibition of apoptosis pathway induced by PI3K/AKT/Bcl-2/BAX pathway in human...
Gab1 regulates SDF-1-induced progression via inhibition of apoptosis pathway induced by PI3K/AKT/Bcl-2/BAX pathway in human... (link.springer.com)
A-Z List of Rare Diseases in Humans | Disabled World
A-Z List of Rare Diseases in Humans | Disabled World (disabled-world.com)
Tumors and Tumorlike Lesions of Bone - Fritz Schajowicz - Häftad (9783642499562) | Bokus
Tumors and Tumorlike Lesions of Bone - Fritz Schajowicz - Häftad (9783642499562) | Bokus (bokus.com)
September 2018, Week 2 - School of Medicine - Pathology | UAB
September 2018, Week 2 - School of Medicine - Pathology | UAB (uab.edu)
Treatments for chondrosarcoma - Canadian Cancer Society
Treatments for chondrosarcoma - Canadian Cancer Society (cancer.ca)
TAF15 Gene - GeneCards | RBP56 Protein | RBP56 Antibody
TAF15 Gene - GeneCards | RBP56 Protein | RBP56 Antibody (genecards.org)
Orbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis | springermedizin.at
Orbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis | springermedizin.at (springermedizin.at)
The Faces of Sarcoma - Page 7
The Faces of Sarcoma - Page 7 (sarcomahelp.org)
The Faces of Sarcoma - Page 2
The Faces of Sarcoma - Page 2 (sarcomahelp.org)
Low-Dose Involved Field Radiation after Chemotherapy in Advanced Hodgkin Disease: A Southwest Oncology Group Randomized Study |...
Low-Dose Involved Field Radiation after Chemotherapy in Advanced Hodgkin Disease: A Southwest Oncology Group Randomized Study |... (annals.org)
MSK path VII Flashcards by Amanda Beach | Brainscape
MSK path VII Flashcards by Amanda Beach | Brainscape (brainscape.com)
Publications - Mayo Clinic
Publications - Mayo Clinic (mayo.edu)
Bone Sarcoma Guidelines: Diagnosis and Classification, Grading and Staging Systems, Treatment
Bone Sarcoma Guidelines: Diagnosis and Classification, Grading and Staging Systems, Treatment (emedicine.medscape.com)
Diagnostic Pathology: Bone. Edition No. 2 - Research and Markets
Diagnostic Pathology: Bone. Edition No. 2 - Research and Markets (researchandmarkets.com)
Types of Bone Sarcoma - Abramson Cancer Center
Types of Bone Sarcoma - Abramson Cancer Center (pennmedicine.org)
Bioline International Official Site (site up-dated regularly)
Bioline International Official Site (site up-dated regularly) (bioline.org.br)
Behandelrichtlijnen kraakbeentumor
Behandelrichtlijnen kraakbeentumor (lumc.nl)
Ewing Sarcoma - Primitive Neuroectodermal Tumor | ARUP Consult
Ewing Sarcoma - Primitive Neuroectodermal Tumor | ARUP Consult (arupconsult.com)
Soft Tissue Tumors. A Multidisciplinary, Decisional Diagnostic Approach
Soft Tissue Tumors. A Multidisciplinary, Decisional Diagnostic Approach (researchandmarkets.com)
Goswami, P., Medhi, N., Sarma, P.K. and Sarmah, B.J. (2008) Case Report Middle Cranial Fossa Arachnoid Cyst in Association with...
Goswami, P., Medhi, N., Sarma, P.K. and Sarmah, B.J. (2008) Case Report Middle Cranial Fossa Arachnoid Cyst in Association with... (scirp.org)
Childhood Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Patient Information [NCI] - North Kansas City Hospital, Kansas City...
Childhood Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Patient Information [NCI] - North Kansas City Hospital, Kansas City... (nkch.org)
Prof. dr Ljiljana Tadić-Latinović | UNIBL
Prof. dr Ljiljana Tadić-Latinović | UNIBL (unibl.org)
Health Library - Adventist HealthCare
Health Library - Adventist HealthCare (adventisthealthcare.com)
Bone Sarcomas
Bone Sarcomas (reininsarcoma.org)
Meninges Hemangiopericytoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
Meninges Hemangiopericytoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials (malacards.org)