Privacy: The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)Confidentiality: The privacy of information and its protection against unauthorized disclosure.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Informed Consent: Voluntary authorization, by a patient or research subject, with full comprehension of the risks involved, for diagnostic or investigative procedures, and for medical and surgical treatment.Genetic Privacy: The protection of genetic information about an individual, family, or population group, from unauthorized disclosure.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Health Insurance Portability and Accountability Act: Public Law 104-91 enacted in 1996, was designed to improve the efficiency and effectiveness of the healthcare system, protect health insurance coverage for workers and their families, and to protect individual personal health information.Consent Forms: Documents describing a medical treatment or research project, including proposed procedures, risks, and alternatives, that are to be signed by an individual, or the individual's proxy, to indicate his/her understanding of the document and a willingness to undergo the treatment or to participate in the research.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Electronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.Bone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.Sarcoma, Ewing: A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. The tumor occurs usually before the age of 20, about twice as frequently in males as in females.Femoral NeoplasmsChondrosarcoma: A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed)Neoplasms, Bone Tissue: Neoplasms composed of bony tissue, whether normal or of a soft tissue which has become ossified. The concept does not refer to neoplasms located in bones.Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.Bone Remodeling: The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.Lipomatosis: A disorder characterized by the accumulation of encapsulated or unencapsulated tumor-like fatty tissue resembling LIPOMA.Hemangiopericytoma: A tumor composed of spindle cells with a rich vascular network, which apparently arises from pericytes, cells of smooth muscle origin that lie around small vessels. Benign and malignant hemangiopericytomas exist, and the rarity of these lesions has led to considerable confusion in distinguishing between benign and malignant variants. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1364)Hamartoma: A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.Glomus Tumor: A blue-red, extremely painful vascular neoplasm involving a glomeriform arteriovenous anastomosis (glomus body), which may be found anywhere in the skin, most often in the distal portion of the fingers and toes, especially beneath the nail. It is composed of specialized pericytes (sometimes termed glomus cells), usually in single encapsulated nodular masses which may be several millimeters in diameter (From Stedman, 27th ed). CHEMODECTOMA, a tumor of NEURAL CREST origin, is also sometimes called a glomus tumor.Lipoma: A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.Hemangioendothelioma: A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866)Lymphangioma: A benign tumor resulting from a congenital malformation of the lymphatic system. Lymphangioendothelioma is a type of lymphangioma in which endothelial cells are the dominant component.Hemangioendothelioma, Epithelioid: A tumor of medium-to-large veins, composed of plump-to-spindled endothelial cells that bulge into vascular spaces in a tombstone-like fashion. These tumors are thought to have "borderline" aggression, where one-third develop local recurrences, but only rarely metastasize. It is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to Kimura's disease (see ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA). (Segen, Dictionary of Modern Medicine, 1992)Radiology: A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease.Lipomatosis, Multiple Symmetrical: A condition characterized by the growth of unencapsulated masses of ADIPOSE TISSUE symmetrically deposited around the neck, shoulders, or other sites around the body.Rectal Neoplasms: Tumors or cancer of the RECTUM.Neoadjuvant Therapy: Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Combined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Antineoplastic Combined Chemotherapy Protocols: The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.Radiotherapy, Adjuvant: Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Chemotherapy, Adjuvant: Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.Sulfonamides: A group of compounds that contain the structure SO2NH2.Mandibular Neoplasms: Tumors or cancer of the MANDIBLE.Fibroma: A benign tumor of fibrous or fully developed connective tissue.Fibroma, Ossifying: A benign central bone tumor, usually of the jaws (especially the mandible), composed of fibrous connective tissue within which bone is formed.Jaw Cysts: Saccular lesions lined with epithelium and contained within pathologically formed cavities in the jaw; also nonepithelial cysts (pseudocysts) as they apply to the jaw, e.g., traumatic or solitary cyst, static bone cavity, and aneurysmal bone cyst. True jaw cysts are classified as odontogenic or nonodontogenic.Mandibular DiseasesRadiography, Panoramic: Extraoral body-section radiography depicting an entire maxilla, or both maxilla and mandible, on a single film.Mandible: The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.Nose: A part of the upper respiratory tract. It contains the organ of SMELL. The term includes the external nose, the nasal cavity, and the PARANASAL SINUSES.Odontogenic Tumors: Neoplasms produced from tooth-forming tissues.Ameloblastoma: An immature epithelial tumor of the JAW originating from the epithelial rests of Malassez or from other epithelial remnants of the ENAMEL from the developmental period. It is a slowly growing tumor, usually benign, but displays a marked propensity for invasive growth.Foreign Bodies: Inanimate objects that become enclosed in the body.Methotrexate: An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.Bone Diseases: Diseases of BONES.Doxorubicin: Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.Neurofibrosarcoma: A malignant tumor that arises from small cutaneous nerves, is locally aggressive, and has a potential for metastasis. Characteristic histopathologic features include proliferating atypical spindle cells with slender wavy and pointed nuclei, hypocellular areas, and areas featuring organized whorls of fibroblastic proliferation. The most common primary sites are the extremities, retroperitoneum, and trunk. These tumors tend to present in childhood, often in association with NEUROFIBROMATOSIS 1. (From DeVita et al., Cancer: Principles & Practice of Oncology, 5th ed, p1662; Mayo Clin Proc 1990 Feb;65(2):164-72)Asparaginase: A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC 3.5.1.1.Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.Liposarcoma: A malignant tumor derived from primitive or embryonal lipoblastic cells. It may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid (LIPOSARCOMA, MYXOID), round-celled, or pleomorphic, usually in association with a rich network of capillaries. Recurrences are common and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces. (From Dorland, 27th ed; Stedman, 25th ed)BostonFibromatosis, Aggressive: A childhood counterpart of abdominal or extra-abdominal desmoid tumors, characterized by firm subcutaneous nodules that grow rapidly in any part of the body but do not metastasize. The adult form of abdominal fibromatosis is FIBROMATOSIS, ABDOMINAL. (Stedman, 25th ed)

Inhibitory effects of transforming growth factor-beta1 pretreatment on experimental pulmonary metastasis of MCS-1 Chinese hamster mesenchymal chondrosarcoma cells. (1/35)

Recent studies have suggested that transforming growth factor(TGF)-beta1 acts as a multifunctional regulator of cell growth, and also modifies tumor progression and metastasis. In the present study, we investigated the effects of TGF-beta1 on the proliferation and experimental pulmonary metastasis of MCS-1. MCS-1 are undifferentiated type cloned tumor cells established from a mesenchymal chondrosarcoma which spontaneously occurred in the soft tissue of a female Chinese hamster. MCS-1 cells were pretreated with TGF-beta1 (0, 0.05, 0.5, 2, 10 ng/ml) for 72 hours in a medium containing 1% fetal bovine serum, then tested for in vitro growth by the MTT method, in vivo growth by subcutaneous inoculation into athymic nude mice (1 x 10(6) cells/mouse) and experimental pulmonary metastasis by injection into the lateral tail vein of athymic nude mice (5 x 10(4) cells/mouse). TGF-beta1 significantly inhibited in vitro growth of MCS-1, depending on its concentrations, and also experimental metastasis with maximal inhibition at 0.5 or 2 ng/ml treatment compared to untreated controls. TGF-beta1, however, was ineffective for in vivo subcutaneous growth of MCS-1. These results indicated that TGF-beta1 might be an inhibitor of metastasis of mesenchymal chondrosarcomas including other types of non-epitherial cartilage or bone formation tumors.  (+info)

Cell differentiation and matrix gene expression in mesenchymal chondrosarcomas. (2/35)

Mesenchymal chondrosarcomas are small-cell malignancies named as chondrosarcomas due to the focal appearance of cartilage islands. In this study, the use of in situ detection techniques on a large series of mesenchymal chondrosarcoma specimens allowed the identification of tumor-cell differentiation pathways in these neoplasms. We were able to trace all steps of chondrogenesis within mesenchymal chondrosarcoma by using characteristic marker genes of chondrocytic development. Starting from undifferentiated cells, which were negative for vimentin and any other mesenchymal marker, a substantial portion of the cellular (undifferentiated) tumor areas showed a chondroprogenitor phenotype with an onset of expression of vimentin and collagen type IIA. Cells in the chondroid areas showed the full expression panel of mature chondrocytes including type X collagen indicating focal hypertrophic differentiation of the neoplastic chondrocytes. Finally, evidence was found for transdifferentiation of the neoplastic chondrocytes to osteoblast-like cells in areas of neoplastic bone formation. These results establish mesenchymal chondrosarcoma as the very neoplasm of differentiating premesenchymal chondroprogenitor cells. The potential of neoplastic bone formation in mesenchymal chondrosarcoma introduces a new concept of neoplastic (chondrocytic) osteogenesis in musculoskeletal malignant neoplasms, which qualifies the old dogma that neoplastic bone/osteoid formation automatically implies the diagnosis of osteosarcoma.  (+info)

Prostaglandin D synthase (beta-trace) in meningeal hemangiopericytoma. (3/35)

The level of prostaglandin D synthase (PGDS), a major protein constituent of cerebrospinal fluid (CSF), is altered in various brain diseases, including meningitis. However, its role in the brain remains unclear. PGDS is mainly synthesized in the arachnoid cells, the choroid plexus and oligodendrocytes in the central nervous system. Among brain tumors, meningiomas showed intense immunoreactivity to PGDS in the perinuclear region. Thus, PGDS has been considered a specific cell marker of meningioma. In this study, we examined 25 meningeal hemangiopericytomas (HPCs) and found that 16 of the tumors (64%) showed immunoreactivity for PGDS in the perinuclear region. For comparison, 15 meningiomas, 14 soft-tissue HPCs, 1 mesenchymal chondrosarcoma, 3 choroid plexus papillomas, and 7 oligodendrogliomas were also examined. Meningiomas showed positive immunoreactivity for PGDS in 13 cases (80%). Except for one case located at the sacrum, none of the other soft-tissue HPCs showed immunostaining for PGDS. Mesenchymal chondrosarcoma arises in the bones of the skull, and its histological pattern resembles that of HPC; however, it showed no immunoreactivity for PGDS. Neither choroid plexus papillomas nor oligodendrogliomas were immunopositive for PGDS. These findings suggest that meningeal HPCs may have a unique molecular phenotype that is distinct from that of the soft-tissue HPCs. The origin of meningeal HPCs may be more closely related to the arachnoid cells.  (+info)

Chondrosarcoma of bone: an oncological and functional follow-up study. (4/35)

We retrospectively analysed the course of 42 out of 45 patients suffering from different chondrosarcomas which were treated surgically. We found a prospective 5- and 10-year survival of 64% for both time intervals. Follow-up examination was possible in 21 of 45 patients. Most of them were staged as NED, one as AWD, and 8 of 45 were lost to follow-up. From 16 dead patients 12 died of the disease and 4 of unknown but not to tumor related reasons. Survival was depending significantly on the histopathological grade, and the stage according to Enneking's surgical staging system. Eleven out of forty-five patients developed metastases within a mean period of twelve months after surgery. The survival of these patients was significantly reduced. Patients with centrally located tumors exhibited a distinct but non-significant worse survival than those suffering from peripheral tumors. In 18% (8 of 45) recurrence of the tumor was evident within a mean period of 24 months (5-85). Functional evaluation was performed in 21 out of 28 alive patients. After a mean follow-up time of 72 months the mean score was 64% (23-100). Females exhibited a distinct but non-significant better result, the same was observed for peripheral locations compared to centrally located tumors. Regarding age, grade, and line of resection no tendency of any dependence was detected, but worst results were seen in those with a stage III tumor and dedifferentiated CS.  (+info)

Translocation der(13;21)(q10;q10) in skeletal and extraskeletal mesenchymal chondrosarcoma. (5/35)

Cytogenetic studies of mesenchymal chondrosarcoma are few and to date, no specific or recurrent aberrations have been found. In this investigation, the cytogenetic and molecular cytogenetic (spectral karyotypic and fluorescence in situ hybridization) findings for two mesenchymal chondrosarcomas, one arising skeletally and the other extraskeletally, are reported. An identical Robertsonian translocation involving chromosomes 13 and 21 [der(13;21)(q10;q10)] was detected in both cases, possibly representing a characteristic rearrangement for this histopathologic entity. Both cases also exhibited loss of all or a portion of chromosomes 8 and 20 and gain of all or a portion of chromosome 12. The observation of similar chromosomal abnormalities in both skeletal and extraskeletal mesenchymal chondrosarcoma supports a genetic as well as histopathologic relationship between these anatomically distinct neoplasms.  (+info)

Retroperitoneal extraskeletal mesenchymal chondrosarcoma in a dog. (6/35)

A young adult female Mastiff dog developed a large retroperitoneal mass, pleural effusion, and multiple pulmonary and pleural nodules. All masses were diagnosed as mesenchymal subtype chondrosarcomas, using histological and immunohistochemical criteria. Reports of canine extraskeletal mesenchymal chondrosarcomas (EMCs) are rare but involved animals less than 3 years of age in 60% of the cases. This is the first description of this type of tumor developing distant metastases. Evidence from this case and previous reports suggests that EMCs are associated with a poor prognosis.  (+info)

Mesenchymal chondrosarcoma originating from the femoral vein. (7/35)

Mesenchymal chondrosarcoma is a rare variant of chondrosarcomas characterized by a bimorphic pattern with areas of the undifferentiated malignant small cells and well differentiated cartilaginous islands.(1) It occurs most commonly in the bone but can also occur in the extraskeletal soft tissues, the brain, and the meninges. This type of tumor has also been described in the eyelids, parapharyngeal space, mediastinum, and the kidney.(1-5) An origin from the large vessels has not been reported in the medical literature. The authors report a case of mesenchymal chondrosarcoma originating from the femoral vein in a 28-year-old female patient, treated by the wide-margin resection.  (+info)

Cytopathology of mesenchymal chondrosarcomas: a report and comparison of four patients. (8/35)

BACKGROUND: Mesenchymal chondrosarcoma (MC) is an infrequent neoplasm, representing approximately 1% of all chondrosarcomas. Cytologic descriptions of MCs have been confined to rare case reports. In the current report, the authors describe their experience with the cytologic features of four MCs: two primary tumors and two metastatic lesions. METHODS: Four patients were diagnosed with MC at the authors' institution from 1994 to 2002. Three of four patients underwent fine-needle aspiration (FNA) biopsy as part of their diagnosis; in the fourth patient, imprint cytology was performed. Each tumor also received histologic confirmation. RESULTS: The patients studied included three females and one male. In three patients, the tumor presented initially as a soft tissue mass; whereas, in the remaining patient, the MC presented in the tibia. FNA results demonstrated small, oval-to-spindled cells with high nuclear-to-cytoplasmic ratios. Cells occurred singly and in clumps in a background of basophilic extracellular matrix. Histologic examination of each lesion demonstrated biphasic tumors, including focal areas of relatively mature cartilage formation as well as a small cell population. CONCLUSIONS: MC is a rare soft tissue tumor that occurs frequently in extraskeletal locations. FNA of these tumors can be diagnostic if the tumor is sampled appropriately and of critical features, such as the background extracellular matrix, are recognized. Given the propensity of these tumors to metastasize and the poor prognosis of patients with MC, early identification by FNA biopsy may allow earlier, more aggressive interventions.  (+info)

*Mesenchymal chondrosarcoma

... is a form of malignant chondrosarcoma. Unlike most chondrosarcomas, mesenchymal chondrosarcoma grows ... October 2000). "Mesenchymal Chondrosarcoma: A Small Cell Neoplasm with Polyphenotypic Differentiation". Int. J. Surg. Pathol. 8 ... dead link] Goldberg, JM & Grier, H (December 2004). "Mesenchymal Chondrosarcoma". ESUN. 1 (6). Müller S, Söder S, Oliveira AM, ... Chen JY, Hsu SS, Ho JT (May 2004). "Extraskeletal intracranial mesenchymal chondrosarcoma: case report and literature review". ...

*IRF2BP2 (gene)

... in mesenchymal chondrosarcoma". PLoS ONE. 7 (11): e49705. doi:10.1371/journal.pone.0049705. PMC 3504151 . PMID 23185413. This ...

*Randy Miller

Miller was diagnosed with mesenchymal chondrosarcoma, a form of bone cancer, in 2008, the same year that With Arrows, With ...

*List of MeSH codes (C04)

... chondrosarcoma MeSH C04.557.450.565.280.280 --- chondrosarcoma, mesenchymal MeSH C04.557.450.565.380 --- giant cell tumors MeSH ... chondrosarcoma MeSH C04.557.450.795.300.280 --- chondrosarcoma, mesenchymal MeSH C04.557.450.795.350 --- fibrosarcoma MeSH ...

*Small-blue-round-cell tumor

... the more common fetal and embryonal types do not Merkel cell carcinoma Mesenchymal chondrosarcoma Endometrial stromal ...

*Index of trauma & orthopaedics articles

Mesenchymal chondrosarcoma - Metaphysis - Metatarsophalangeal joint sprain - Microfracture surgery - Milch classification - ... Myxoid chondrosarcoma National hip fracture database - Neer classification - Neer impingement sign - Neer's prosthesis - ... Chondrosarcoma - Chopart's fracture-dislocation - Clarke's test - Clavicle fracture - Clay-shoveler fracture - Cleidocranial ...

*International Classification of Diseases for Oncology

Myxoid chondrosarcoma M9240/3 Mesenchymal chondrosarcoma M9241/0 Chondromyxoid fibroma M9242/3 Clear cell chondrosarcoma M9243/ ... NOS Mixed mesenchymal tumor M8990/3 Mesenchymoma, malignant Mixed mesenchymal sarcoma M8991/3 Embryonal sarcoma M9000/0 Brenner ... M9221/0 Juxtacortical chondroma Periosteal chondroma M9221/3 Juxtacortical chondrosarcoma Periosteal chondrosarcoma M9230/0 ... 3 Dedifferentiated chondrosarcoma M9250/1 giant cell tumor of bone, NOS Osteoclastoma, NOS M9250/3 Giant cell tumor of bone, ...

*Cancer epigenetics

... histogenetically heterogeneous mesenchymal tumors that for example include chondrosarcoma, Ewing's sarcoma, leiomyosarcoma, ... Expression of epigenetic modifiers such as that of the BMI1 component of the PRC1 complex is deregulated in chondrosarcoma, ... Similarly, expression of another epigenetic modifier, the LSD1 histone demethylase, is increased in chondrosarcoma, Ewing's ... is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma". Hum ...

*Chondrosarcoma

IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal ... Therapeutic molecular targets in human chondrosarcoma .Int J Exp Pathol 2010; 91:387-93 Chondrosarcoma of Bone Chondrosarcoma ... Chondrosarcoma is a cancer composed of cells derived from transformed cells that produce cartilage. Chondrosarcoma is a member ... File:Metastatic chondrosarcoma at the lower lip.jpgFile:Metastatic chondrosarcoma at the lower lip.jpg Imaging studies - ...

*Sarcoma

A sarcoma is a cancer that arises from transformed cells of mesenchymal origin. Thus, malignant tumors made of cancellous bone ... Some sarcomas, such as leiomyosarcoma, chondrosarcoma, and gastrointestinal stromal tumor (GIST), are more common in adults ... For example, osteosarcoma resembles bone, chondrosarcoma resembles cartilage, liposarcoma resembles fat, and leiomyosarcoma ... Extraskeletal chondrosarcoma (9220/3) Extraskeletal osteosarcoma (9180/3) Fibrosarcoma (8810/3) Gastrointestinal stromal tumor ...

*WHO classification of tumours of the central nervous system

3.2 Mesenchymal tumours 3.2.1 Lipoma (ICD-O 8850/0) 3.2.2 Angiolipoma (ICD-O 8861/0) 3.2.3 Hibernoma (ICD-O 8880/0) 3.2.4 ... 3.2.13 Chondrosarcoma (ICD-O 9220/3) 3.2.14 Osteoma (ICD-O 9180/0) 3.2.15 Osteosarcoma (ICD-O 9180/3) 3.2.16 Osteochondroma ( ...

*IFFO1

However, the gene has been found to be highly expressed in chondrosarcoma. Chondrosarcoma is the cancer of the cells that ... especially mesenchymal cells. The vimentin protein is also responsible for maintaining cell shape, integrity of the cytoplasm, ... Therefore, there seems to be an association between IFFO1's filamentous characteristic and chondrosarcoma. One nuclear export ...

*Chondroblast

Chondrosarcoma is a more malignant type of tumor, but most are low grade tumors and often appear in the axial skeletal region. ... Day, Timothy F.; Guo, Xizhi; Garrett-Beal, Lisa; Yang, Yingzi (2005). "Wnt/β-Catenin Signaling in Mesenchymal Progenitors ... Chondroblasts, or perichondrial cells, is the name given to mesenchymal progenitor cells in situ which, from endochondral ... Use of the term is technically inaccurate since mesenchymal progenitors can also technically differentiate into osteoblasts or ...

*Ectomesenchymal chondromyxoid tumor

... mesenchymal cells. There are some who think it is a myoepithelial tumor type. Derived from ectomesenchymal cells migrating from ... extraskeletal myxoid chondrosarcoma, focal oral mucinosis, and an ossifying fibromyxoid tumor of soft parts. Exceedingly rare, ...

*List of cancer types

... each of which develop from cells originating in mesenchymal cells outside the bone marrow. Lymphoma and leukemia: These two ... Chondrosarcoma Ewing's sarcoma Malignant fibrous histiocytoma of bone/osteosarcoma Osteosarcoma Rhabdomyosarcoma Heart cancer ...

*Chondroblastoma

Romeo et al have observed chondroblastoma neoplasms to be composed of mesenchymal cells that have completed normal ... clear cell chondrosarcomas, and enchondromas (this list is not exhaustive). Chondroblastoma has not been known to spontaneously ... These findings suggest that chondroblastoma is derived from a mesenchymal cell undergoing chondrogenesis via active growth- ... any definitive determinations regarding the origin of this neoplasm are not possible because of the plasticity of mesenchymal ...

*List of OMIM disorder codes

GDF5 Chondrosarcoma; 215300; EXT1 Chondrosarcoma, extraskeletal myxoid; 612237; TAF15 Chondrosarcoma, extraskeletal myxoid; ... RSPO4 Anterior segment mesenchymal dysgenesis; 107250; FOXE3 Anterior segment mesenchymal dysgenesis; 107250; PITX3 ... 612237; TFG Chondrosarcoma, extraskeletal myxoid; 612237; CSMF Chorea, hereditary benign; 118700; NKX2-1 Choreoacanthocytosis; ...

*Osteosarcoma

Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and ... Differential diagnosis of the osteosarcoma of the skull in particular includes, among others, chondrosarcoma and the ...

*Index of oncology articles

... chondrosarcoma - chordoma - chorioallantoic membrane - choriocarcinoma - choroid plexus tumor - CHPP - chronic granulocytic ... mesenchymal - mesenteric membrane - mesna - mesonephroma - mesothelioma - metaplasia - metaplastic carcinoma - metastasectomy ...
However, differential diagnosis may be problematic at early stages with other ossified lesions of soft tissues: benign lesions such as myositis ossificans circumscripta (MOC), ossifying lipoma, soft tissue osteoma or chondroma, and ossifying fibromyxoid tumour, as well as malignant lesions such as classical high-grade ESOS, parosteal OS, mesenchymal chondrosarcoma, and synovial sarcoma. MOC is a benign heterotopic ossification of soft tissues characteristically associated with direct trauma [15]. It is one of the most important differential diagnoses, which was initially evoked - based on radiological and/or pathological aspects - in at least 3 out of the 7 reported cases of low-grade ESOS. Furthermore, a number of cases of ESOS presumably arising from MOC have been reported [16-19]. In MOC, both mature and immature bone is seen, as well as a prominent spindle cell and chondroid component, with a specific architecture described as the "zonal phenomenon". This phenomenon refers to the presence of ...
... , long-time bassist of The Icarus Line, has died. He had been battling a rare form of cancer (mesenchymal chondrosarcoma), and finally lost the fight a few hours ago. As someone who has met him several times over the years, I am genuinely saddened by his passing. He was a "cool dude". May you […]. ...
Ewing sarcoma shows considerable histologic overlap with other round cell tumors. NKX2-2, a homeodomain transcription factor involved in neuroendocrine/glial differentiation and a downstream target of EWSR1-FLI1, has been reported as an immunohistochemical marker for Ewing sarcoma. We assessed the specificity of NKX2-2 for Ewing sarcoma compared with other round cell malignant neoplasms and other soft tissue tumors with EWSR1 translocations. We evaluated whole-tissue sections from 270 cases: 40 Ewing sarcomas (4 with atypical/large cell features), 20 CIC-DUX4 sarcomas, 5 BCOR-CCNB3 sarcomas, 9 unclassified round cell sarcomas, 10 poorly differentiated synovial sarcomas, 10 lymphoblastic lymphomas, 10 alveolar rhabdomyosarcomas, 10 embryonal rhabdomyosarcomas, 10 Merkel cell carcinomas, 10 small cell carcinomas, 20 melanomas, 5 NUT midline carcinomas, 10 Wilms tumors, 10 neuroblastomas, 10 olfactory neuroblastomas, 12 mesenchymal chondrosarcomas, 10 angiomatoid fibrous histiocytomas, 10 clear ...
55 year old male with dedifferentiated chondrosarcoma and pathological fracture. Final Diagnosis: Left proximal femur and soft tissues, en bloc excision: Dedifferentiated chondrosarcoma High grade, grade 3/3 Maximum size 14.6 cm Tumor is ba...
... , Authors: Andreas F Mavrogenis, Panayiotis J Papagelopoulos. Published in: Atlas Genet Cytogenet Oncol Haematol.
As for the genetics and causes of the cancer, it has been rather hard to find sources which can determine the cause of it, from the website…. The genetic changes specific to chondrosarcoma continue to be investigated extensively. Although studies have not yet established a specific or recurrent karyotypic feature for any of these tumors, different chondrosarcomas have demonstrated anomalies in several tumor suppressor genes, oncogenes, and transcription factors, including TP53, RAS, EXT1, EXT2, and Sox9. Available cytogenetic and comparative genomic hybridization (CGH) studies reveal changes in some chondrosarcomas, but fail to do so in others. These studies are thus far difficult to interpret.. Based on the available studies, it is likely that chondrosarcomas are generated by a coordinated, multi-step process involving primarily tumor suppressor genes. In fact, the complexity and variety of genetic changes seen in chondrosarcomas may indicate several distinct genetic pathways. Some of the ...
OBJECTIVE: To determine whether, in human fibroblasts and chondrosarcoma cells, the regulation of interleukins (IL)-6, 8, and 11 and matrix metalloproteinases (MMP)-1, 3, and 13, and their tissue inhibitor TIMP-1, depends on the transcription factor nuclear factor-kappaB (NF-kappaB). METHODS: Fibroblasts and chondrosarcoma cells were effectively infected with an adenovirus encoding human IkappaBalpha, and inhibition of NF-kappaB function was observed. The induction of MMP and IL-6, 8, and 11 by various stimuli was assessed by ELISA. RESULTS: The induction of IL-6 and IL-8 clearly depended on NF-kappaB in both fibroblasts and chondrosarcoma cells, irrespective of stimulus, but IkappaBalpha overexpression had little effect on IL-11. MMP-1, -3, and -13 were also inhibited, but TIMP-1 was unaffected. CONCLUSION: NF-kappaB appears to play an important and selective role in MMP induction in human fibroblasts and chondrosarcoma cells. This suggests there are NF-kappaB dependent mechanisms of cartilage ...
Chondrosarcomas are a primitive malignant tumor that derives from cartilage cells. It usually appears at the center of a bone segment, with no pre-existing lesions (central chondrosarcoma). It may also be secondary to a pre-existent condition suc...
Purpose: Chondrosarcomas are notoriously resistant to cytotoxic chemotherapeutic agents. We sought to identify critical signaling pathways that contribute to their survival and proliferation, and which may provide potential targets for rational therapeutic interventions. Experimental Design: Activation of receptor tyrosine kinases (RTKs) was surveyed using phospho-RTK arrays. S6 phosphorylation and NRAS mutational status were examined in chondrosarcoma primary tumor tissues. Small interfering RNA or small molecule inhibitors against RTKs or downstream signaling proteins were applied to chondrosarcoma cells and changes in biochemical signaling, cell cycle, and cell viability were determined. In vivo anti-tumor activity of BEZ235, a phosphoinositide-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor, was evaluated in a chondrosarcoma xenograft model. Results: Several RTKs were identified as critical mediators of cell growth, but the RTK dependencies varied among cell lines. In ...
Chondrosarcoma is a type of cancer that develops in cartilage cells. Cartilage is the specialized, gristly connective tissue that is present in adults and the tissue from which most bones develop. Cartilage plays an important role in the growth process. There are many different types of cartilage that are present throughout the body. Chondrosarcoma is a malignant type of bone cancer that primarily affects the cartilage cells of the femur (thighbone), arm, pelvis, and knee. Although less frequent, other areas (such as the ribs) may be affected.. Chondrosarcoma is the second most common type of primary bone cancer. A primary bone cancer is one that originates from bone, as opposed to starting in another organ and then spreading to the bone. This type of cancer rarely affects individuals under age 20 and continues to rise until age 75. The incidence between males and females is equal.. ...
Chondrosarcoma is a type of cancer that develops in cartilage cells. Cartilage is the specialized, gristly connective tissue that is present in adults and the tissue from which most bones develop. Cartilage plays an important role in the growth process. There are many different types of cartilage that are present throughout the body. Chondrosarcoma is a malignant type of bone cancer that primarily affects the cartilage cells of the femur (thighbone), arm, pelvis, and knee. Although less frequent, other areas (such as the ribs) may be affected.. Chondrosarcoma is the second most common type of primary bone cancer. A primary bone cancer is one that originates from bone, as opposed to starting in another organ and then spreading to the bone. This type of cancer rarely affects individuals under age 20 and continues to rise until age 75. The incidence between males and females is equal.. ...
Chondrosarcomas are characteristic for their slow but progressive invasion of the surrounding tissues. These malignant, cancerous tumors originate in the cartilage, the connective tissue between bones.
Clear-cell chondrosarcoma is a variant of chondrosarcoma which is characterized by a typical histomorphology and a very slow rate of growth. A case is presented in which the tumor was located in the maxilla. show less ...
... is a malignant type of bone cancer that primarily affects the cartilage cells of the femur, arm, pelvis, knee, and spine.
Chondrosarcoma treatments include chemotherapy, radiation therapy, targeted therapies, and surgery, to remove the mass and reduce the likelihood of return.
Learn more about Chondrosarcoma at Coliseum Health System DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision .....
No. of Printed Pages : 3 MCA (Revised) MCS-012 Term-End Examination tr) June, 2011 cNI 0 ,--. MCS-012 : COMPUTER ORGANISATION & ASSEMBLY LANGUAGE
AIMS: Neuroblastoma shows considerable histological overlap with other small round blue cell tumours. PHOX2B, a transcription factor that is essential for autonomic nervous system development, has been reported as an immunohistochemical marker for neuroblastoma. The aim of this study was to validate the specificity and diagnostic utility of PHOX2B for peripheral neuroblastic tumours. METHODS AND RESULTS: We evaluated 240 cases (133 in whole-tissue sections; 107 in tissue microarrays), including 76 peripheral neuroblastic tumours (median age 2 years; including four adults) and 164 other tumours: 44 Wilms tumours; 20 Ewing sarcomas; 10 each of CIC-rearranged round cell sarcomas, poorly differentiated synovial sarcomas, lymphoblastic lymphomas, alveolar rhabdomyosarcomas, embryonal rhabdomyosarcomas, mesenchymal chondrosarcomas, Merkel cell carcinomas, olfactory neuroblastomas, and melanomas; and five each of NUT midline carcinomas and desmoplastic small round cell tumours ...
Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant metastasis. Chondrosarcoma shows a predilection for metastasis to the lungs. Interleukin-8 (IL-8), a chemokine with a defining CXC amino acid motif, is known to possess tumorigenic and proangiogenic properties. Over-expression of IL-8 has been detected in many human tumors. However, the effects of IL-8 in migration and integrin expression in chondrosarcoma cells are largely unknown. In this study, we found that IL-8 increased the migration and the expression of αvβ3 integrin in human chondrosarcoma cells. Activations of phosphatidylinositol 3-kinase (PI3K), Akt, and AP-1 pathways after IL-8 treatment were demonstrated, and IL-8-induced expression of integrin and migration activity was inhibited by the specific inhibitor and mutant of PI3K, Akt, and AP-1 cascades. Taken together, our results indicated that IL-8 enhances the migration of chondrosarcoma cells by increasing αvβ3 integrin ...
Chondrosarcomas are malignant cartilage tumors that do not respond to traditional chemotherapy or radiation. The 5-year survival rate of histologic grade III chondrosarcoma is less than 30%. To achieve a greater understanding of chondrosarcoma tumorigenesis, a model for human chondrosarcoma has been established in a rat system. The model, known as the Swarm rat chondrosarcoma (SRC), resembles human chondrosarcoma and provides a system to study tumor growth and progression. Here we examined the influence of the tumor microenvironment and the impact of genome-wide hypomethylation on the behavior of SRC tumors, two factors known to contribute fundamentally to the development and progression of solid tumors. Previous studies with SRC revealed that tumor microenvironment can significantly influence chondrosarcoma malignancy, but the underlying biologic mechanisms have not been defined. To address this issue we carried out epigenetic and gene expression studies on the SRC tumors that were initiated at
Imaging studies - including radiographs ("x-rays"), computerized tomography (CT), and magnetic resonance imaging (MRI) - are often used to make a presumptive diagnosis of chondrosarcoma. However, a definitive diagnosis depends on the identification of malignant cancer cells producing cartilage in a biopsy specimen that has been examined by a pathologist. In a few cases, usually of highly anaplastic tumors, immunohistochemistry (IHC)is required.. There are no blood tests currently available to enable an oncologist to render a diagnosis of chondrosarcoma. The most characteristic imaging findings are usually obtained with CT.. Nearly all chondrosarcoma patients appear to be in good health. Often, patients are not aware of the growing tumor until there is a noticeable lump or pain. Earlier diagnosis is generally accidental, when a patient undergoes testing for another problem and physicians discover the cancer. Occasionally the first symptom will be a broken bone at the cancerous site. Any broken ...
Get information, facts, and pictures about Chondrosarcoma at Encyclopedia.com. Make research projects and school reports about Chondrosarcoma easy with credible articles from our FREE, online encyclopedia and dictionary.
We report an unusual case of a young woman with chondrosarcoma affecting the greater cornu of the hyoid bone. Only a handful of reports of primary chondrosarcoma involving the hyoid exist in the world literature. The case described presented as a swe
Although a rare entity, chondrosarcoma is the most common malignant tumor of the chest wall. Most patients present with an enlarging, painful anterior chest wall mass arising from the costochondrosternal junction. CT scan with intravenous contrast is the gold standard radiographic study for diagnosis and operative planning. Contrary to previous dictum, resection may be performed in an appropriate surgical candidate based on imaging characteristics or image-guided percutaneous biopsy results; incisional biopsy is rarely required. The keys to successful treatment are early recognition and radical excision with adequate margins, as chondrosarcoma is relatively resistant to radiotherapy and conventional cytotoxic chemotherapy. Overall survival is excellent in most surgical series from experienced centers. Complete excision with widely negative microscopic margins at the initial operation is of the utmost importance, as local recurrence portends systemic metastasis and eventual tumor-related mortality. This
Depending on the type of chondrosarcoma, it may spread slowly or very rapidly. Its presently unknown what causes this type of cancer. This is partially because it is so unusual that there are not a lot of cases to study. A higher incidence of nasal CSAs among cats living in urban areas may indicate a link to air pollution. The type affecting bones has been found to contain viruses in the cells of the tumor, suggesting a viral connection. Some bone tumors develop on the site of a previous fracture, which may mean theres a link with the bodys cells that heal a broken bone. But its believed that several factors combine with each unique cats physiology to cause the cells to become cancerous ...
A chondrosarcoma is one of several types of laryngeal tumors that can effect the larynx and trachea of a dog. This is a relatively rare and fast spreading tumor that originates in the cartilage, a connective collagenous tissue that is found throughout the body.
Gentaur molecular products has all kinds of products like :search , US Biomax \ Osteosarcoma and chondrosarcoma tissue array, with stage, grade and TNM data, 80 cases_80 cores, replacing OS801 and BC26111; ihc Anti-Actin confirmed \ OS802 for more molecular products just contact us
Pain is the usual presenting symptom; alternatively the tumour may be found incidentally on imaging. Signs are localise to the involved bone. Imaging appearances are difficult as most chondrosarcomas resemble benign chondroma. The most common features are of central lucency with expansion and thickening of the overlying cortex.. ...
These deficits are summarized in Display 10-17, the lesions are charac- terized by a bimorphic pattern that is composed of highly undifferentiated small round cells and islands of well- differentiated hyaline cartilage. Judicial procedures It is exaemn established that governing body disciplinary procedures Propranolo subject to the propranтlol of natural justice. L.
The primary purpose of this study is to determine if the administration of a higher dose would decrease the chance of tumor recurrence, compared to the risk of tumor recurrence with a lower dose. Most of the treatment will be given protons, but participants may receive a small portion of treatment with x-rays, because less radiation is given to the skin with x-rays. This study uses two slightly different doses of radiation It is not clear at this time which of the dose levels is better ...
The primary purpose of this study is to determine if the administration of a higher dose would decrease the chance of tumor recurrence, compared to the risk of tumor recurrence with a lower dose. Most of the treatment will be given protons, but participants may receive a small portion of treatment with x-rays, because less radiation is given to the skin with x-rays. This study uses two slightly different doses of radiation It is not clear at this time which of the dose levels is better ...
Axial T2 weighted MR image again demonstrates the mass with typical high signal lobular growth pattern of cartilage representing cap.
The actuarial 5- and 10-year survival rates after GKS were 80 and 53%, respectively. The actuarial 5- and 10-year local tumor control (LTC) rates after single or multiple GKS sessions were 76 and 67%, respectively. All patients with low-grade chondrosarcomas achieved good LTC. A tumor volume of less than 20 ml significantly affected the high rate of LTC (p = 0.0182). No patient had adverse radiation effects, other than one in whom facial numbness worsened despite successful tumor control. ...
Human chondrosarcomas do not respond to current chemotherapies or radiation therapy, and their size and histological appearance do not reliably predict the risk of local recurrence and metastases, making selection of surgical treatment difficult. Identifying mechanisms responsible for the proliferation and invasive behavior of these tumors would be of immense clinical value. We hypothesized that telomerase expression is one of these mechanisms. We detected telomerase expression in 7 of 16 chondrosarcomas, but cells cultured from telomerase-negative chondrosarcomas acquired strong telomerase activity and lost tumor suppressor activity after their establishment in culture. These changes were associated with accelerated indefinite cell proliferation, morphological transition, and increased invasive activity, indicating that telomerase activation and loss of cell cycle control leads to the emergence of aggressive cells from chondrosarcoma cell populations. These observations may lead to better ...
The study, "Lost miRNA surveillance of Notch, IGFR pathway - road to sarcomagenesis," was published in the January issue of Tumor Biology, the official journal of the International Society of Oncology and BioMarkers. Sarcomas are a group that makes up more than 60 different tumors that affect bone and connective tissues. Chondrosarcomas are the second most common bone malignancy and do not respond to conventional therapy. Together with H. Thomas Temple, M.D., professor and Vice Chair of Orthopedics and Director of the Tissue Bank, who in 2010 established the Musculoskeletal Oncology Signal Transduction Laboratory to investigate the molecular pathways leading to metastatic sarcomas, Galoian and her team compared and analyzed differentially expressed miRNA and their targets in chondrosarcoma versus control chondrocytes. "Under normal conditions, mesenchymal cells support and produce a matrix for connective tissues; however, the signaling events resulting in mesenchymal cell transformation to ...
Chondrosarcoma is categorized as a malignant cartilaginous tumor, which occurs rarely in the craniofacial region. We report the case of a 68-year-old man with chondrosarcoma in the subglottic area. His chief symptoms were hoarseness and mild dysphagi
Chondroid tumors are predominantly lesions of the axial skeleton but can infrequently have an extraskeletal origin. Primary intracranial chondrosarcomas constitute ,0.16% of all brain tumors, an overwhelming majority of which are skull base tumors (1, 2). They are thought to arise from undifferentiated cells from cartilaginous synchondroses (1-3, 6, 7). Much less common sites include the falx, choroid plexus, and convexity. The histogenesis at this site is uncertain but is thought to arise from the pluripotent cells of the meninges.. Primary chondrosarcomas can be classified as mesenchymal, myxoid, or classical based on their cytoarchitecture. In the series published by Korten et al (2), which included 15 case reports plus 177 cases from a review of the literature, no sex dominance was shown. Ages varied from 3 months to 76 years, with a mean age of 37 years. Considering the rarity of occurrence of intracranial chondrosarcomas, it was difficult to establish a clear demographic pattern; however, ...
Cyclooxygenase (COX)-2, the inducible isoform of prostaglandin (PG) synthase, has been implicated in tumor metastasis. Interaction of COX-2 with its specific EP receptors on the surface of cancer cells has been reported to induce cancer invasion. However, the effects of COX-2 on migration activity in human chondrosarcoma cells are mostly unknown. In this study, we examined whether COX-2 and EP interaction are involved in metastasis of human chondrosarcoma. We found that over-expression of COX-2 or exogenous PGE2 increased the migration of human chondrosarcoma cells. We also found that human chondrosarcoma tissues and chondrosarcoma cell lines had significant expression of the COX-2 which was higher than that in normal cartilage. By using pharmacological inhibitors or activators or genetic inhibition by the EP receptors, we discovered that the EP1 receptor but not other PGE receptors is involved in PGE2-mediated cell migration and α2β1 integrin expression. Furthermore, we found that human
BioAssay record AID 79237 submitted by ChEMBL: In vitro cytotoxicity in chondrosarcoma cell line (H-EMC-SS) by Alamar blue assay.
Marco wants to wait at least 8 weeks to let everything heal up and also allow us time to decide where to go from here. My initial feelings lean toward the complete knee replacement. The other concern is of the cancer spreading to the lungs. I had a c.t. scan before surgery that revealed no tumors in the lungs. However, the cancer is slow-growing so it could already be there and just not visible. I will continually have c.t. scans to check That is our update. Please continue to pray for Jenny as she is due with our second baby in less than 1 month. Also pray for Zeke as he is in the difficult transition from only child to soon to be little brother (which is only complicated with all the added stress of my medical conditions ...
(2009) Kim et al. Molecular Cancer. Background: High expression of P-glycoprotein is one of the well-known mechanisms of chemoresistance in chondrosarcomas. However, the role of antiapoptotic proteins, a common mechanism responsible for chemoresistance in other tumors, has not been well studied i...
... While testing the mcs7780 based IrDA USB dongle Ive stumbled upon memory leak in mcs_net_close(). Patch below fixes it. Signed-off-by: Hinko Kocevar ,[EMAIL PROTECTED], Signed-off-by: Samuel Ortiz ,[EMAIL PROTECTED], Signed-off-by: David S. Miller ,[EMAIL PROTECTED], --- drivers/net/irda/mcs7780.c , 2 ++ 1 files changed, 2 insertions(+), 0 deletions(-) diff --git a/drivers/net/irda/mcs7780.c b/drivers/net/irda/mcs7780.c index 0b76919..93916cf 100644 --- a/drivers/net/irda/mcs7780.c +++ b/drivers/net/irda/mcs7780.c @@ -677,6 +677,8 @@ static int mcs_net_close(struct net_device *netdev) /* Stop transmit processing */ netif_stop_queue(netdev); + kfree_skb(mcs-,rx_buff.skb); + /* kill and free the receive and transmit URBs */ usb_kill_urb(mcs-,rx_urb); usb_free_urb(mcs-,rx_urb); - To unsubscribe from this list: send the line unsubscribe git-commits-head in the body of a message to [EMAIL PROTECTED] More majordomo info at ...
Chondrosarcoma of the pelvis and upper end of the femur. An analysis of factors influencing survival time in one hundred and thirteen cases. Journal of Bone and Joint Surgery - American Volume. 1972 ...
For the past two years, there has been a growing concern over the safety of the manmade chemical known as C-8 or PFOA (perfluorooctanoic acid) which can be
A microactuator for precisely aligning an optical fiber with an optical device includes a carrier having at least one bimorphic actuator which bends or deflects in response to electrical stimuli to thereby controllably position the carrier and, in turn, an optical fiber mounted on the carrier, with an optical device, such as a laser diode. The bimorphic actuator includes first and second layers of first and second materials, respectively, which respond differently to electrical stimuli. For example, the first and second materials can have different coefficients of thermal expansion or one of the materials can be a piezoelectric material such that application of electrical stimuli to the bimorphic actuator will deflect the actuator by a precisely controllable amount. The carrier can also be mounted on an alignment support structure such that upon deflecting the bimorphic actuator is urged against a portion of the alignment support structure so as to
Answer: Chondrosarcoma. Histology: none provided. Discussion: Chondrosarcomas are malignant proliferations of cartilage which tend to occur in the axial skeleton of older people. The radiograph in this case is helpful to diagnose a malignant tumor because of its destructive and aggressive permeative pattern. Histologically the cartilage shows atypical nuclei and a permeative growth pattern around native trabeculae. This permeative growth pattern is diagnostic of malignancy in most primary bone tumors. The radiograph, however, is a most important tool leading to the diagnosis of chondrosarcoma.. Although metastatic carcinoma is the most common bone tumor in this age group, there is no evidence of epithelial cells in this case.. Enchondromas occasionally occur in the pelvis. Occasionally, the cartilage of enchondroma can show atypia. However, the destructive and aggressive radiographic pattern precludes the diagnosis of an enchondroma. Therefore, the radiograph should always be consulted when ...
Twenty-eight patients with histologically confirmed chordomas (18) or chondrosarcomas (10) underwent Gamma Knife SRS either as primary or adjuvant treatment. Their ages ranged from 17 to 72 years (median 44 years). The most common presenting symptom was diplopia (26 patients, 93%). In two patients, SRS was the sole treatment. Twenty-six patients underwent between one and five additional surgical procedures. Two underwent an initial trans-sphenoidal biopsy. The average tumor volume was 9.8 cm3. The median dose to the tumor margin was 16 Gy. ...
In this study, we investigated the anticancer effects of a new benzimidazole derivative, 1-benzyl-2-phenyl -benzimidazole (BPB), in human chondrosarcoma cells. BPB-mediated apoptosis was assessed by the MTT assay and flow cytometry analysis. The in vivo efficacy was examined in a JJ012 xenograft model. Here we found that BPB induced apoptosis in human chondrosarcoma cell lines (JJ012 and SW1353) but not in primary chondrocytes. BPB induced upregulation of Bax, Bad and Bak, downregulation of Bcl-2, Bid and Bcl-XL and dysfunction of mitochondria in chondrosarcoma. In addition, BPB also promoted cytosolic releases AIF and Endo G. Furthermore, it triggered extrinsic death receptor-dependent pathway, which was characterized by activating Fas, FADD and caspase-8. Most importantly, animal studies revealed a dramatic 40% reduction in tumor volume after 21 days of treatment. Thus, BPB may be a novel anticancer agent for the treatment of chondrosarcoma.
OncoLink, the Webs first cancer resource,provides comprehensive information on coping with cancer, cancer treatments, cancer research advances, continuing medical education, cancer prevention, and clinical trials
An adult male squirrel monkey with severe bilateral exophthalmia and conjunctivitis was euthanatized. Necropsy revealed, in a sagittal section of the head (Fig. 135), a gray-white mass involving the...
Farese, JP, Kirpensteijn, J, Kik, M, Bacon, NJ, Waltman, SS, Seguin, B, Kent, M, Liptak, J, Straw, R, Chang, MN, Jiang, Y and Withrow, SJ (2009) Biologic Behavior and Clinical Outcome of 25 Dogs with Canine Appendicular Chondrosarcoma Treated by Amputation: A Veterinary Society of Surgical Oncology Retrospective Study ...
Well, we are apparently creating a lovely, safe-haven for aphids and other small bugs, beetles, etc. in our cabbage bed. When we harvested a few of the Komatsuna asian greens the other day, there were definitely little collections of aphids scattered throughout the leaves, but it didnt seem as though much of the plant had…
NCOA4兔多克隆抗体(ab111885)可与人样本反应并经IHC实验严格验证。中国75%以上现货,所有产品均提供质保服务,可通过电话、电邮或微信获得本地专属技术支持。
article{52f6a2c0-7074-42f4-ae84-0c0dbf6711b3, abstract = {,p,Rat chondrosarcoma chondrocytes were labeled with [,sup,3,/sup,H]serine or [,sup,3,/sup,H]mannose as a precursor. Intracellular proteoglycan core protein precursor was purified from cell lysates by immunoprecipitation with polyclonal antibodies against the hyaluronic acid-binding region, followed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The core precursor was eluted from the gels and treated with alkaline borohydride in order to convert serine residues substituted with xylose or N-acetylgalactosamine to alanine (or with alkaline sulfite to convert them to cysteic acid). After acid hydrolysis, the proportions of labeled serine and alanine (or cysteic acid) were determined by high performance liquid chromatography, and the results were compared with those obtained for the completed proteoglycan molecules isolated from the same cultures. In the completed proteoglycans, about 55% of the serine residues were substituted ...
The anatomic junction of the neural and facial viscerocranium is termed the skull base (). This area is critically important because it supports the brain and allows all the neurovascular structures to either enter or exit the skull.Neoplasms may ori
The Anti-Cancer Effect of a Novel Nutrient Mixture by Inhibiting MMPs Expression, Invasion and Inducing Apoptosis in Chondrosarcoma Cell Line SW-1353
Outdoor Power Equipment and Other Small Engine Mechanics Career Overview Profile with short video, earnings, outlook, knowledge, skills, abilities, typical tasks and activities, training requirements, nature of the work, occupations and academic programs
Es un sistema de diagnóstico de alta tecnología eléctrico y óptico que fusiona tecnología informática, óptica, estudio de imágenes, principios ergonómicos y colposcopia, para que pueda tener una evaluación más precisa en el sector fronterizo donde no poda
Radiographic findings of 15 untreated chondrosarcomas of the cranial and facial bones were reviewed. These tumors have a propensity to occur in the wall of a maxillary sinus, at the junction of sphenoid and ethmoid sinuses and vomer, and at the undersurface of the sphenoid bone. Because of its slow-growing nature, chondrosarcomas tend to be large, multilobulated, and sharply demarcated when detected. Frequent bone changes are a combination of erosion and destruction, with sharp transitional zones and absent periosteal reaction. Tumor matrix calcifications, not necessarily chondroid, are almost always present. Both CT and MR may be necessary for thorough evaluation of tumor extent. ...
MULLER, Daniel Curvello de Mendonça et al. Hemipelvectomy in the treatment of chondrosarcoma of the acetabulum dog. Cienc. Rural [online]. 2010, vol.40, n.5, pp.1218-1222. ISSN 1678-4596. http://dx.doi.org/10.1590/S0103-84782010000500036.. Hemipelvectomy is the removal of part of the pelvis and is indicated for the surgical treatment of malignant tumors. This study presents the case of a canine patient with recurrent chondrosarcoma, submitted to hemipelvectomy with limb amputation. The report aims to highlight the importance of surgery in the treatment of radial bone chondrosarcoma, addressing a viable and unconventional alternative for patients suffering from tumors in the pelvis, which against the extension of the lesion may be misdiagnosed as intractable cancer. After the partial hemipelvectomy with amputation of the limb the animal satisfactory returned to ambulation without difficulty in supporting or alteration in balance.. Keywords : neoplasm; pelvis; cancer surgery; dogs. ...
Sarcoma is a peer-reviewed, Open Access journal dedicated to publishing papers covering all aspects of connective tissue oncology research. It brings together work from scientists and clinicians carrying out a broad range of research in this field, including the basic sciences, molecular biology and pathology and the clinical sciences of epidemiology, surgery, radiotherapy and chemotherapy. High-quality papers concerning the entire range of bone and soft tissue sarcomas in both adults and children, including Kaposis sarcoma, are published as well as preclinical and animal studies.
Angptl4 - Angptl4 (Myc-DDK-tagged ORF) - Rat angiopoietin-like 4 (Angptl4), (10 ug) available for purchase from OriGene - Your Gene Company.
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Primary extraskeletal osteosarcoma (ESOS) presenting in thoracic locations is very rare and associated with a poor prognosis. The current study presents a case involving a large anterior mediastinal mass, which was histologically confirmed as a primary osteosarcoma. The literature concerning primary …
Nitric Oxide And Other Small Signalling Molecules Volume 72 Advances In Microbial Physiology can be very useful guide, and Nitric Oxide And Other Small Signalling Molecules Volume 72 Advances In Microbial Physiology play an important role in your products. The problem is that once you have gotten your nifty new product, the Nitric Oxide And Other Small Signalling Molecules Volume 72 Advances In Microbial Physiology gets a brief glance, maybe a once over, but it often tends to get discarded or lost with the original packaging. ...
Background Tracheal autotransplantation is a reconstructive technique that allows for organ-sparing treatment of selected patients with advanced cricoid cartilage chondrosarcoma and T2 or T3...
We were delayed in finding these spots because some misogynistic prick of a hip doctor tried to convince her that the pain was just mental and contrived. No, I didnt punch him. I was kind of in shock when he said it and missed my opportunity. I figured if I went back to physically harm this jerk, it would no longer be a defensible crime. So we might try for this guys medical license and hit him where it really hurts. Hell in this Trump era of politics, we might be able to send that guy back to Iran. I kid, I kid. Anyways, if you can relay a request or two for us and ask God to covet the minds and souls of the new team of doctors, that would be appreciated. We just met them at your old stomping grounds at Hopkins. Boy, did that bring back memories. After our first consult/meeting, we have decided they will assume all her care with regards to this hip/spine/leg/chondrosarcoma stuff. Still, no definitive answers without more tests. So we wait for pre-authorization from insurance. If the insurance ...
Molecular Cloning, also known as Maniatis, has served as the foundation of technical expertise in labs worldwide for 30 years. No other manual has been so popular, or so influential.

Pathology of Hemangiopericytoma - Dr Sampurna Roy MDPathology of Hemangiopericytoma - Dr Sampurna Roy MD

Mesenchymal chondrosarcoma ; Phosphaturic mesenchymal tumour; Osteosarcoma; Malignant mesotheliomas ; Thymomas ; Sarcomatoid ...
more infohttp://www.histopathology-india.net/HP.htm

Metastatic mesenchymal chondrosarcomaMetastatic mesenchymal chondrosarcoma

Extraskeletal mesenchymal chondrosarcoma. Radiology 1993;186:819-26. [ Links ]. 13. Aryoshi Y, Shimahara M. Mesenchymal ... It has also been established that mesenchymal chondrosarcoma expresses Sox-9 gene, a regulator in mesenchymal cell ... Mesenchymal chondrosarcoma of the jaws. Oral Surg Oral Md Oral Pathol 1982;54:197-206. [ Links ]. ... Mesenchymal chondrosarcoma of bone and soft tissue. A review of 111 cases. Cancer 1986;57:2444-453. [ Links ]. ...
more infohttp://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1681-150X2010000200013&lng=pt&nrm=iso

Metastatic mesenchymal chondrosarcomaMetastatic mesenchymal chondrosarcoma

Extraskeletal mesenchymal chondrosarcoma. Radiology 1993;186:819-26. [ Links ]. 13. Aryoshi Y, Shimahara M. Mesenchymal ... It has also been established that mesenchymal chondrosarcoma expresses Sox-9 gene, a regulator in mesenchymal cell ... Mesenchymal chondrosarcoma of the jaws. Oral Surg Oral Md Oral Pathol 1982;54:197-206. [ Links ]. ... Mesenchymal chondrosarcoma of bone and soft tissue. A review of 111 cases. Cancer 1986;57:2444-453. [ Links ]. ...
more infohttp://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1681-150X2010000200013&lng=es&nrm=iso&tlng=es

Mesenchymal Chondrosarcoma in Children and Young Adults: A Single Institution Retrospective ReviewMesenchymal Chondrosarcoma in Children and Young Adults: A Single Institution Retrospective Review

... Michael W. Bishop,1,2 ... Mesenchymal chondrosarcoma is an aggressive, uncommon histologic entity arising in bone and soft tissues. We reviewed our ... We conducted a retrospective chart review on patients with mesenchymal chondrosarcoma over a 24-year period. Clinicopathologic ... Aggressive surgical resection of mesenchymal chondrosarcoma with chemoradiotherapy yields excellent local control and may ...
more infohttps://www.hindawi.com/journals/sarcoma/2015/608279/abs/

Mesenchymal chondrosarcoma - WikipediaMesenchymal chondrosarcoma - Wikipedia

Mesenchymal chondrosarcoma is a form of malignant chondrosarcoma. Unlike most chondrosarcomas, mesenchymal chondrosarcoma grows ... October 2000). "Mesenchymal Chondrosarcoma: A Small Cell Neoplasm with Polyphenotypic Differentiation". Int. J. Surg. Pathol. 8 ... dead link] Goldberg, JM & Grier, H (December 2004). "Mesenchymal Chondrosarcoma". ESUN. 1 (6). Müller S, Söder S, Oliveira AM, ... Chen JY, Hsu SS, Ho JT (May 2004). "Extraskeletal intracranial mesenchymal chondrosarcoma: case report and literature review". ...
more infohttps://en.wikipedia.org/wiki/Mesenchymal_chondrosarcoma

Mesenchymal chondrosarcoma of maxilla in paediatric patient | BMJ Case ReportsMesenchymal chondrosarcoma of maxilla in paediatric patient | BMJ Case Reports

Mesenchymal chondrosarcoma (MCS) is a rare subtype of CS that is more aggressive and may lead to erroneous diagnosis in a ... Chondrosarcoma (CS) is a malignant tumour of long and flat bone characterised by the formation of cartilage. ...
more infohttps://casereports.bmj.com/content/12/3/e228969

Response to: Periosteal mesenchymal chondrosarcoma of the tibia | Springer for Research & DevelopmentResponse to: Periosteal mesenchymal chondrosarcoma of the tibia | Springer for Research & Development

Khalil and colleagues for their comments [1]. We agree that the discovery of the fusion testing in mesenchymal chondrosarcoma ... Periosteal mesenchymal chondrosarcoma of the tibia. Skeletal Radiol. https://doi.org/10.1007/s00256-018-2885-9. ... It is true that molecular testing with its increasing availability now can be helpful in establishing diagnosis of mesenchymal ... chondrosarcomas, particularly those with less than optimal pathologic features or sampling. We intend to make use of testing ...
more infohttps://rd.springer.com/article/10.1007/s00256-018-2914-8

Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon...Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon...

Identification of the novel HEY1-NCOA2 fusion in the mesenchymal chondrosarcoma case UF5. A, Upper: partial schema of HEY1 and ... RT-PCR detection of the HEY1-NCOA2 fusion in additional mesenchymal chondrosarcoma cases. Upper panel: RT-PCR performed using ... Exon expression plot of NCOA2 in the mesenchymal chondrosarcoma sample UF5, showing the intragenic change in NCOA2 expression. ... Interphase FISH detection of HEY1-NCOA2 fusion in mesenchymal chondrosarcomas. A, the schema of FISH-probe design. B, ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/22034177

Chondrosarcoma, Mesenchymal - Semantic ScholarChondrosarcoma, Mesenchymal - Semantic Scholar

Mesenchymal chondrosarcomas have a predilection for flat bones; long tubular bones are rarely affected. They tend to occur in ... A rare aggressive variant of chondrosarcoma, characterized by a biphasic histologic pattern of small compact cells intermixed ... Chondrosarcoma, Mesenchymal. Known as: Chondrosarcomas, Mesenchymal, chondrosarcoma mesenchymal, Mesenchymal Chondrosarcoma ( ... Chondrosarcoma with additional mesenchymal component (dedifferentiated chondrosarcoma). I. A clinicopathologic study of 26 ...
more infohttps://www.semanticscholar.org/topic/Chondrosarcoma%2C-Mesenchymal/141503

Mesenchymal Chondrosarcoma of the Sinonasal Cavity: A Case Report and  by Kevin P. Banks, Justin Q. Ly et al."Mesenchymal Chondrosarcoma of the Sinonasal Cavity: A Case Report and " by Kevin P. Banks, Justin Q. Ly et al.

Histologically, mesenchymal chondrosarcomas are characterized by a mix of cartilage and undifferentiated stromal tissue. ... We present a case of mesenchymal chondrosarcoma presenting as chronic sinusitis, arising in the sinonasal cavity. Additionally ... Radiographically, they demonstrate features similar to the more commonly encountered conventional chondrosarcoma, with the ... Mesenchymal chondrosarcoma is a rare, highly malignant cartilaginous forming tumor that is rarely encountered in clinical ...
more infohttps://corescholar.libraries.wright.edu/surg/454/

Primary mesenchymal chondrosarcoma of the kidney with synchronous implant and infiltrating urothelial carcinoma of the ureter |...Primary mesenchymal chondrosarcoma of the kidney with synchronous implant and infiltrating urothelial carcinoma of the ureter |...

We report a case of primary mesenchymal chondrosarcoma occurring in the left kidney with an ipsilateral and distinct distal ... This is the first reported case of a primary mesenchymal chondrosarcoma of the kidney with coexisting infiltrating urothelial ... Histopathological examination and immunohistochemical studuies showed the classic features of mesenchymal chondrosarcoma in ... suggested that the development of the urothelial carcinoma in the ureter may be triggered or induced by the chondrosarcoma ...
more infohttps://diagnosticpathology.biomedcentral.com/articles/10.1186/1746-1596-7-125

Soft Tissue Sarcoma | Vanderbilt-Ingram Cancer CenterSoft Tissue Sarcoma | Vanderbilt-Ingram Cancer Center

Extraskeletal mesenchymal chondrosarcoma. Treatment of extraskeletal mesenchymal chondrosarcoma may include the following: * ... Extraskeletal mesenchymal chondrosarcoma . This type of bone and cartilage tumor often affects young adults and occurs in the ... Extraskeletal myxoid chondrosarcoma. Treatment of extraskeletal myxoid chondrosarcoma may include the following:. * Surgery to ... Extraskeletal myxoid chondrosarcoma . This type of soft tissue sarcoma may occur in children and adolescents. Over time, it ...
more infohttps://www.vicc.org/cancer-info/childhood-soft-tissue-sarcoma

January/February 2012 - Volume 17 - Issue 1 : AJSP: Reviews & ReportsJanuary/February 2012 - Volume 17 - Issue 1 : AJSP: Reviews & Reports

Mesenchymal Chondrosarcoma of the Chest Wall. Borys, Dariusz; Canter, Robert J. Borys, Dariusz; Canter, Robert J. Less ...
more infohttp://journals.lww.com/pathologycasereviews/toc/2012/01000

Chondrosarcoma: Practice Essentials, Background, PathophysiologyChondrosarcoma: Practice Essentials, Background, Pathophysiology

Chondrosarcoma is a collective term for a group of tumors that consist predominantly of cartilage and that range from low-grade ... Mesenchymal chondrosarcoma. The 5-year survival rate for mesenchymal chondrosarcoma is less than 50%, with an overall 10-year ... Fewer than 2% of all chondrosarcomas are mesenchymal chondrosarcomas. The maxilla and the mandible are the most common sites of ... encoded search term (Chondrosarcoma) and Chondrosarcoma What to Read Next on Medscape. Related Conditions and Diseases. * Fast ...
more infohttps://emedicine.medscape.com/article/1258236-overview

Bone Sarcomas | Johns Hopkins MedicineBone Sarcomas | Johns Hopkins Medicine

Mesenchymal chondrosarcoma. * Neurofibroma of bone (schwannoma). * Osteoblastoma. * Pagets disease/pagetoid osteosarcoma. * ...
more infohttps://www.hopkinsmedicine.org/health/conditions-and-diseases/sarcoma/bone-sarcomas

Diagnostic Radiology/Musculoskeletal Imaging/Tumors Advanced - Wikibooks, open books for an open worldDiagnostic Radiology/Musculoskeletal Imaging/Tumors Advanced - Wikibooks, open books for an open world

1. Cartilaginous a. Mesenchymal chondrosarcoma 2. Osseous a. High grade surface osteosarcoma 3. Fibrous and fibrohistiocytic a ...
more infohttps://en.wikibooks.org/wiki/Diagnostic_Radiology/Musculoskeletal_Imaging/Tumors_Advanced

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With...Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With...

Mesenchymal (extraskeletal) chondrosarcoma. *Leiomyosarcoma. *Liposarcoma (excluding myxoid liposarcoma). *Undifferentiated ... extraskeletal myxoid chondrosarcoma, neoplasms with perivascular epithelioid cell differentiation (PEComa), intimal sarcoma, ... atypical fibroxanthoma, mixed tumor NOS, phosphaturic mesenchymal tumor, malignant ossifying fibromyxoid tumor, malignant mixed ...
more infohttps://clinicaltrials.gov/ct2/show/record/NCT02180867?show_locs=Y

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With...Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With...

Mesenchymal (extraskeletal) chondrosarcoma. *Leiomyosarcoma. *Liposarcoma (excluding myxoid liposarcoma). *Undifferentiated ... extraskeletal myxoid chondrosarcoma, neoplasms with perivascular epithelioid cell differentiation (PEComa), intimal sarcoma, ... atypical fibroxanthoma, mixed tumor NOS, phosphaturic mesenchymal tumor, malignant ossifying fibromyxoid tumor, malignant mixed ...
more infohttps://clinicaltrials.gov/ct2/show/record/NCT02180867

Bone SarcomasBone Sarcomas

Mesenchymal Chondrosarcoma. This rare form of chondrosarcoma is a deadly high grade sarcoma consisting of primitive mesenchymal ... Clear Cell Chondrosarcoma. Clear Cell Chondrosarcoma is a destructive low-grade malignant tumor which presents in adults. Clear ... Chondrosarcoma. This is a cancer of that usually grows within a bone or on its surface. It is most typically found in middle- ... Chondrosarcoma is usually a slow-growing tumor and the most common sites are the pelvis, shoulder, and the upper part of the ...
more infohttps://www.reininsarcoma.org/what-is-sarcoma-2/bone-sarcomas/

Distinct computed tomography features of non-small-cell lung cancer in a European population with EML4-ALK translocation |...Distinct computed tomography features of non-small-cell lung cancer in a European population with EML4-ALK translocation |...

Orbito-maxillofacial mesenchymal chondrosarcoma with intracranial invasion and lung metastasis. short review ... frequent expression of epithelial-mesenchymal transition markers than other genotype. PLOS ONE. 2013;8(10):e76999. doi: 10.​ ...
more infohttps://www.springermedizin.at/distinct-computed-tomography-features-of-non-small-cell-lung-can/14930876

Publications of Nancy M MajorPublications of Nancy M Major

Mesenchymal chondrosarcoma (MC) is an infrequent neoplasm, representing approximately 1% of all chondrosarcomas. Cytologic ... Cytopathology of mesenchymal chondrosarcomas: a report and comparison of four patients.}, Journal = {Cancer, United States}, ... Chondrosarcoma, Mesenchymal • Female • Humans • Male • Middle Aged • Neoplasm Metastasis • Prognosis • pathology* • secondary ... There are potential pitfalls in discriminating gout from pseudogout and synovial chondromatosis from chondrosarcoma.CONCLUSIONS ...
more infohttp://fds.duke.edu/db?pubs-22-58-4910-0--0-1

Global Chondrosarcoma Market Report 2017 Estimated To Grow Worldwide By 2022: Global QYResearch | MedgadgetGlobal Chondrosarcoma Market Report 2017 Estimated To Grow Worldwide By 2022: Global QYResearch | Medgadget

This report studies Global Chondrosarcoma Market, especially in North America, China, Europe, Southeast Asia, Japan and India, ... Conventional Chondrosarcoma. Clear Cell Chondrosarcoma. Myxoid Chondrosarcoma. Mesenchymal Chondrosarcoma. Dedifferentiated ... 1.2.4 Mesenchymal Chondrosarcoma. 1.2.5 Dedifferentiated Chondrosarcoma. 1.2.6 Others. 1.3 Applications of Chondrosarcoma. 1.3. ... 6.3.3 Myxoid Chondrosarcoma of Chondrosarcoma Growth Driving Factor Analysis. 6.3.4 Mesenchymal Chondrosarcoma of ...
more infohttps://www.medgadget.com/2017/12/global-chondrosarcoma-market-report-2017-estimated-to-grow-worldwide-by-2022-global-qyresearch.html

Mandible | Ear, Nose & Throat JournalMandible | Ear, Nose & Throat Journal

Mesenchymal chondrosarcoma of the mandible: A rare malignant tumor September 18, 2014 , Rakesh Kumar Singh, MS; Saurabh ... Mesenchymal chondrosarcoma (MCHS) is a highly aggressive, malignant, cartilaginous tumor that represents about 1% of all ... chondrosarcomas. Only about 50 cases of MCHS of the jaw have been reported in the English-language literature; maxillary tumors ...
more infohttps://www.entjournal.com/category/head-and-neck/mandible

Bone Sarcoma Types | SARCBone Sarcoma Types | SARC

Mesenchymal Chondrosarcoma. This rare bone tumor shows a mixture of aggressive small round blue cells mixed with more typical ... This version of chondrosarcoma has a high risk of recurrence, even greater than that of grade 3 conventional chondrosarcoma ( ... Conventional Chondrosarcoma. Conventional chondrosarcoma can be a difficult tumor to treat. It often arises in older patients, ... A version of chondrosarcoma called clear-cell chondrosarcoma has an intermediate risk of metastasis, but treatment is typically ...
more infohttps://sarctrials.org/bone-sarcoma
  • Long-term results of phase II study of high dose photon/proton radiotherapy in the management of spine chordomas, chondrosarcomas, and other sarcomas. (springer.com)
  • However, it is scarcely reported that SDF-1-Gab1 pathway mediates proliferation and apoptosis in human chondrosarcoma (CS). (springer.com)
  • We report a case of primary mesenchymal chondrosarcoma occurring in the left kidney with an ipsilateral and distinct distal ureteric implant, and a coexisting infiltrating urothelial carcinoma of the ureter in a 64-year-old man. (biomedcentral.com)
  • The mesenchymal component often exhibits a haemangiopericytic pattern with multiple vascular spaces ( Figure 4 ).The tumour cells were immunohistochemically reactive for CD99 and negative for S100. (scielo.org.za)
  • As the name implies, cells biopsied from this type of chondrosarcoma appear clear with many large vacuoles. (encyclopedia.com)
  • Multitarget fluorescence in situ hybridization (FISH) suggested that the development of the urothelial carcinoma in the ureter may be triggered or induced by the chondrosarcoma component. (biomedcentral.com)