Chondrocalcinosis: Presence of calcium salts, especially calcium pyrophosphate, in the cartilaginous structures of one or more joints. When accompanied by attacks of goutlike symptoms, it is called pseudogout. (Dorland, 27th ed)Phosphate Transport Proteins: Membrane proteins that are involved in the active transport of phosphate.Azores: A group of nine islands and several islets belonging to Portugal in the north Atlantic Ocean off the coast of Portugal. The islands are named after the acores, the Portuguese for goshawks, living there in abundance. (Webster's New Geographical Dictionary, 1988, p102 & Room, Brewer's Dictionary of Names, 1992, p42)Calcium Pyrophosphate: An inorganic pyrophosphate which affects calcium metabolism in mammals. Abnormalities in its metabolism occur in some human diseases, notably HYPOPHOSPHATASIA and pseudogout (CHONDROCALCINOSIS).Parenteral Nutrition, Home: The at-home administering of nutrients for assimilation and utilization by a patient who cannot maintain adequate nutrition by enteral feeding alone. Nutrients are administered via a route other than the alimentary canal (e.g., intravenously, subcutaneously).Hyperostosis, Diffuse Idiopathic Skeletal: A disease of elderly men characterized by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions.Diphosphates: Inorganic salts of phosphoric acid that contain two phosphate groups.Knee Joint: A synovial hinge connection formed between the bones of the FEMUR; TIBIA; and PATELLA.Metacarpophalangeal Joint: The articulation between a metacarpal bone and a phalanx.Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.Wrist Joint: The joint that is formed by the distal end of the RADIUS, the articular disc of the distal radioulnar joint, and the proximal row of CARPAL BONES; (SCAPHOID BONE; LUNATE BONE; triquetral bone).Arthrography: Roentgenography of a joint, usually after injection of either positive or negative contrast medium.Gout: Hereditary metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi.Hyperparathyroidism: A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.Parathyroidectomy: Excision of one or more of the parathyroid glands.Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Dictionaries, ChemicalRheumatic Diseases: Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.Rheumatology: A subspecialty of internal medicine concerned with the study of inflammatory or degenerative processes and metabolic derangement of connective tissue structures which pertain to a variety of musculoskeletal disorders, such as arthritis.Incidental Findings: Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA.Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Menisci, Tibial: The interarticular fibrocartilages of the superior surface of the tibia.Arthroscopy: Endoscopic examination, therapy and surgery of the joint.Knee Injuries: Injuries to the knee or the knee joint.Rotator Cuff: The musculotendinous sheath formed by the supraspinatus, infraspinatus, subscapularis, and teres minor muscles. These help stabilize the head of the HUMERUS in the glenoid fossa and allow for rotation of the SHOULDER JOINT about its longitudinal axis.Tears: The fluid secreted by the lacrimal glands. This fluid moistens the CONJUNCTIVA and CORNEA.Anterior Cruciate Ligament: A strong ligament of the knee that originates from the posteromedial portion of the lateral condyle of the femur, passes anteriorly and inferiorly between the condyles, and attaches to the depression in front of the intercondylar eminence of the tibia.Fractures, Cartilage: Breaks in CARTILAGE.Diagnosis-Related Groups: A system for classifying patient care by relating common characteristics such as diagnosis, treatment, and age to an expected consumption of hospital resources and length of stay. Its purpose is to provide a framework for specifying case mix and to reduce hospital costs and reimbursements and it forms the cornerstone of the prospective payment system.International Classification of Diseases: A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (From ICD-10, p1). The Clinical Modifications, produced by the UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S.Dry Eye Syndromes: Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.Elbow: Region of the body immediately surrounding and including the ELBOW JOINT.Elbow Joint: A hinge joint connecting the FOREARM to the ARM.Clinical Coding: Process of substituting a symbol or code for a term such as a diagnosis or procedure. (from Slee's Health Care Terms, 3d ed.)Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.Synovitis: Inflammation of a synovial membrane. It is usually painful, particularly on motion, and is characterized by a fluctuating swelling due to effusion within a synovial sac. (Dorland, 27th ed)Tenosynovitis: Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.ArthritisEncyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Organizations, Nonprofit: Organizations which are not operated for a profit and may be supported by endowments or private contributions.Musculoskeletal System: The MUSCLES, bones (BONE AND BONES), and CARTILAGE of the body.Musculoskeletal Physiological Phenomena: Processes and properties of the MUSCULOSKELETAL SYSTEM.MedlinePlus: NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.Arthritis, Gouty: Arthritis, especially of the great toe, as a result of gout. Acute gouty arthritis often is precipitated by trauma, infection, surgery, etc. The initial attacks are usually monoarticular but later attacks are often polyarticular.Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.Gout Suppressants: Agents that increase uric acid excretion by the kidney (URICOSURIC AGENTS), decrease uric acid production (antihyperuricemics), or alleviate the pain and inflammation of acute attacks of gout.Hyperuricemia: Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.Urate Oxidase: An enzyme that catalyzes the conversion of urate and unidentified products. It is a copper protein. The initial products decompose to form allantoin. EC 1.7.3.3.

Pseudogout attack associated with chronic thyroiditis and Sjogren's syndrome. (1/143)

A 66-year-old woman, diagnosed with chronic thyroiditis at age 63, presented with anorexia and fatigue. Therapy for the chronic thyroiditis consisted of levothyroxine sodium (100 microg/day). Her symptoms were attributed to the insufficient supply of levothyroxine sodium. Following a dosage increase to 150 microg/day, she suffered from an acute attack of pseudogout. Clinical features were complicated by Sjogren's syndrome, which appeared after treatment onset. Pseudogout was effectively treated by colchicine after administration of diclofenac sodium failed to alleviate the symptoms. Pseudogout is a recognized complication of thyroid replacement therapy, but association with Sjogren's syndrome has not been previously reported.  (+info)

Chondrocalcinosis after parathyroidectomy. (2/143)

In this retrospective study of 57 patients with primary hyperparathyroidism who underwent parathyroidectomy, the overall incidence of chondrocalcinosis was 40%. Neither joint symptoms nor chondrocalcinosis regressed after the operation. In several patients the condition appeared to deteriorate both clinically and radiologically after the operation, while in a few both the chondrocalcinosis and the associated symptoms first appeared some time after the operation.  (+info)

Transduction mechanisms of porcine chondrocyte inorganic pyrophosphate elaboration. (3/143)

OBJECTIVE: To investigate cellular signaling mechanisms that influence chondrocyte production of inorganic pyrophosphate (PPi), which promotes calcium pyrophosphate dihydrate (CPPD) crystal deposition. METHODS: Articular chondrocyte and cartilage cultures were stimulated with protein kinase C (PKC) activator and adenyl cyclase activator. Generation of extracellular PPi was measured. RESULTS: Adenyl cyclase activation resulted in diminished pyrophosphate generation. PKC activation stimulated pyrophosphate elaboration. CONCLUSION: Two signaling pathways, cAMP and PKC, modulate generation of extracellular pyrophosphate by cartilage and chondrocytes. They are novel targets for potentially diminishing extracellular pyrophosphate elaboration that leads to CPPD crystal deposition.  (+info)

Elevated parathyroid hormone 44-68 and osteoarticular changes in patients with genetic hemochromatosis. (4/143)

OBJECTIVE: To determine whether the osteoarticular changes associated with genetic hemochromatosis could be explained by metabolic parathyroid hormone (PTH) disorders. METHODS: The study involved 210 patients with liver iron overload syndromes. Osteoarticular changes were numerically scored as the number of damaged joints. PTH 1-84 and 44-68 were assayed. RESULTS: An increase in serum PTH 44-68 levels was found in one-third of untreated patients who had no calcium or PTH 1-84 abnormalities. Serum PTH 44-68 levels correlated positively with serum ferritin levels. In multivariate analyses, the number of affected joints correlated positively with age, serum PTH 44-68 levels, and serum ferritin levels. CONCLUSION: Liver iron overload syndromes, especially genetic hemochromatosis, are associated with elevated circulating levels of PTH fragments containing the 44-68 region, which appears to play a role in osteoarticular changes. This increase seems to be a consequence of iron overload.  (+info)

Phosphocitrate blocks nitric oxide-induced calcification of cartilage and chondrocyte-derived apoptotic bodies. (5/143)

OBJECTIVE: To examine whether phosphocitrate (PC) will block nitric oxide-induced calcification of cartilage or chondrocyte-derived apoptotic bodies. DESIGN: Articular cartilage vesicles (ACV) or apoptotic bodies (AB) were isolated from untreated or 1mM sodium nitroprusside (SNP) treated porcine cartilage slices. Mineralization of ACV, AB, control untreated and SNP-treated cartilage were done in the presence or absence of PC (1mM)+/-ATP (1mM). RESULTS: PC [1mM] blocked both the ATP-dependent and -independent mineralization in ACV and AB, untreated and SNP treated cartilage. Moreover, PC had no effect on NTPPPH activity in either ACV or AB fraction in the presence or absence of ATP suggesting that PC did not block the mineralization through the inhibition of NTPPPH activity. CONCLUSIONS: PC inhibits nitric oxide-induced calcification of cartilage and cartilage-derived apoptotic bodies.  (+info)

Most calcium pyrophosphate crystals appear as non-birefringent. (6/143)

OBJECTIVE: To determine the proportion of calcium pyrophosphate dihydrate (CPPD) crystals that appear as non-birefringent when observed under the polarised light microscope. METHODS: Two observers examined independently 10 synovial fluid samples obtained during an episode of arthritis attributable to CPPD crystals. Ten synovial fluid samples from patients with acute gout were used as a reference. The examination was performed after placing a fluid sample in a Niebauer haemocytometric chamber; a crystal count was done first under ordinary light, then in the area corresponding to a 0.1 ml, under polarised light RESULTS: The percentages of birefringence appreciated for CPPD were 18% (confidence intervals (CI) 12, 24) for observer 1, and 17% (CI 10, 24) for observer 2 (difference NS). The percentages of birefringence for monosodium urate were 127% (CI 103, 151) for observer 1 and 107% (CI 100, 114) for observer 2 (difference NS). Percentages above 100% indicate that crystals missed under ordinary light became apparent under polarised light. CONCLUSION: Only about one fifth of all CPPD crystals identified by bright field microscopy show birefringence when the same synovial fluid sample is observed under polarised light. If a search for CPPD crystals is conducted under polarised light, the majority of the crystals will be missed. Ordinary light allows a better rate of CPPD crystal detection but observation under polarised light of crystals showing birefringence is required for definitive CPPD crystal identification.  (+info)

Exclusion of the gene for human cartilage intermediate layer protein in currently mapped calcium pyrophosphate dihydrate deposition syndromes. (7/143)

OBJECTIVE: To map the gene for human cartilage intermediate layer protein (CILP) in order to assess its involvement in some familial forms of calcium pyrophosphate dihydrate (CPPD) deposition disease. METHODS: A radiation hybrid panel was analyzed for chromosomal assignment of the CILP gene within a 1-cM limit of resolution. The location of the gene for CILP was confirmed to reside at the observed radiation hybrid locus by fluorescence in situ hybridization. RESULTS: The human CILP gene resides at chromosome 15q21. CONCLUSION: This map location definitively excludes mutations in the CILP gene as the cause of certain familial forms of CPPD deposition disease that have been genetically mapped to chromosomes 8q and 5p.  (+info)

Seasonal variation in the onset of acute microcrystalline arthritis. (8/143)

OBJECTIVE: To determine whether acute attacks of uric acid and calcium pyrophosphate microcrystalline arthritis show a seasonal variation and, if so, to verify whether the distribution of single episodes shows a rhythmic circannual pattern. METHOD: All suspected cases of microcrystalline acute arthritis observed at the General Hospital of Ferrara during an 8 yr period (January 1990-December 1997) were considered. Diagnosis was made on the basis of history, physical examination and analysis of synovial fluid by means of polarized light microscopy. Month and day of each event were categorized both into four 3-month periods (by seasons) and 12 monthly intervals. Two different statistical methods have been utilized: chi(2) test for goodness of fit and partial Fourier series. RESULTS: During the period considered, 210 episodes of acute gout were observed [196 in males (93.3%) and 14 in females (6.7%)] in 179 different subjects, and 179 episodes of acute pseudogout [58 in males (32.4%) and 121 in females (67.6%)] in 165 different subjects. Gout attacks showed a higher frequency peak in spring [76 cases (36. 2%), P<0.001]. Analysis of distribution of events by gender confirmed the clear spring pattern in males (36.2%), whereas the paucity of cases in females did not allow any valid statistical analysis. Pseudogout attacks showed a higher frequency peak in autumn [52 cases (29.1%)], without reaching a statistically significant level either for the total sample or for subgroups divided by gender. Analysis of the seasonal distribution of gout or pseudogout events was significantly different (chi(2) 15.7, P=0.001). Chronobiological evaluation by means of Fourier analysis showed a circannual pattern for gout attacks, both for the total sample (P=0.006) and the male subgroup (P=0.003), characterized by a peak in April and a trough in October. Again, as for pseudogout events, no seasonal variation was found, either for the total sample or subgroups by gender. CONCLUSIONS: The present study gives further confirmation that acute gout attacks exhibit a circannual distribution in their occurrence, being more frequent in April, whereas pseudogout attacks do not. Moreover, the seasonal distribution of gout and pseudogout acute events is significantly different.  (+info)

Calcium pyrophosphate dihydrate crystals are associated with a range of clinical syndromes, which have been given various names, based upon which clinical symptoms or radiographic findings are most prominent.[11] A task force of the European League Against Rheumatism (EULAR) made recommendations on preferred terminology.[5] Accordingly, calcium pyrophosphate deposition (CPPD) is an umbrella term for the various clinical subsets, whose naming reflects an emphasis on particular features. For example, pseudogout refers to the acute symptoms of joint inflammation or synovitis: red, tender, and swollen joints that may resemble gouty arthritis (a similar condition in which monosodium urate crystals are deposited within the joints). Chondrocalcinosis,[2][3] on the other hand, refers to the radiographic evidence of calcification in hyaline and/or fibrocartilage. "Osteoarthritis (OA) with CPPD" reflects a situation where osteoarthritis features are the most apparent. Pyrophosphate arthropathy refers to ...
Synonyms: Pseudogout, chondrocalcinosis, pyrophosphate arthropathy.. ICD-9 Codes: Pseudogout, 712.2; CPPD crystal deposition disease, 712.2; chondrocalcinosis, 712.3.. Definition: CPPD crystal deposition disease includes arthritic syndromes associated with CPPD crystal deposition disease in articular tissues. The following definitions are used here:. -Chondrocalcinosis: Calcification of articular cartilage (identified by x-ray).. -Chronic CPPD crystal deposition disease: Structural bone and cartilage abnormalities associated with intraarticular deposition of CPPD crystals.. -Pseudogout: Clinical syndrome of acute synovitis caused by intraarticular CPPD crystal deposition, the most common form of CPPD crystal deposition disease.. Etiology: The cause of CPPD crystal deposition disease is unknown. Formation of CPPD crystals in cartilage may be related to matrix changes or result from elevated levels of calcium or inorganic pyrophosphate. Some cases appear to be hereditary, whereas others are ...
In all cases, in the first group, in which both US and radiographs were positive for the presence of calcifications, a large number of either intra- or extracellular CPPD crystals were found. In one case where MSU crystals were found, no specific US signs were found. The patient presented moderate articular swelling and important functional limitation due to pain. The US picture showed effusion and mild synovitis of the wrist joint.. Pattern II was the most common (found in at least one site in all patients). The third pattern was found in one patient with a large effusion in the subacromial bursae, where several mobile hyperechoic deposits were seen. A large number of CPPD crystals was found in the synovial fluid analysis, so we believe that the third pattern is seen when crystal aggregates are formed.. To our knowledge, only a few studies on the use of US in CPPD disease have been carried out, mostly in the knee joint. In these studies, average sensitivity and specificity in detecting ...
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Pseudogout is a type of arthritis that, as the name implies, can cause symptoms similar to gout, but which are a reaction to a different type of crystal deposit. This type of arthritis may be one of the most misunderstood forms, and is often mistaken for gout and other conditions, including RA. Proper diagnosis is important because untreated pseudogout may lead to a severe form of joint degeneration and ongoing inflammation, resulting in chronic disability.. Pseudogout develops when deposits of calcium pyrophosphate crystals accumulate in a joint. Initially, crystals deposit in the cartilage and can cause damage. They also can cause a reaction with inflammation that leads to joint pain and swelling. This can cause more chronic arthritis that mimics osteoarthritis or RA. Knees are most often involved, but wrists, shoulders, ankles, elbows, and hands can be affected. Ultimately, a patient with pseudogout could be incapacitated for days or weeks.. ...
The crowned dens syndrome (CDS), also known as periodontoid calcium pyrophosphate dehydrate crystal deposition disease, is typified clinically by severe cervical pain, neck stiffness and atlantoaxial synovial calcification which could be misdiagnosed
Mohammad Sami Walid 1, Joshua C. Yelverton 2, Mohammed Ajjan 3, Arthur A. Grigorian 3. Medical Center of Central Georgia 1, Mercer University 2, Georgia Neurosurgical Institute 3, USA. Abstract. Objective & Importance: Crystal-induced arthritis (gout and pseudogout) usually affects peripheral joints whereas spine involvement with severe myelopathy is extremely rare. PubMed search yielded 42 results for gout myelopathy and 35 results for pseudogout myelopathy .. Clinical Presentation: We are reporting the case of a 62 years old female Caucasian who presented with severe thoracic myelopathy. MRI of the spine with contrast showed a 1.0´1.7 cm epidural soft tissue nodule with peripheral enhancement posterior to the thoracic cord at T9-10.. Intervention: Decompression and excision of the lesion was performed. Pathology revealed rhomboid-shaped, positively birefringent crystals. Uric acid was normal. The diagnosis of pseudogout was established.. Conclusion: Spinal crystal arthropathy should be ...
In need of more information about this disease if anyone has it. I am waiting for my informational appt with my doctor but am looking for info in the meantime. Questions are: what is prognosis? How does disease usually progress? DOES it usually spread to other joints, or is it impossible to know for sure if it wiil? Is it the same as pseudogout and CPPD or just associated with them..how does it differ? Is it a rheumatological disease or metabolic? Ive heard it described as both and Im not sure what the difference is. Thanks to anyone that can help me while I wait to see my doctor!. Reply Follow This Thread Stop Following This Thread Flag this Discussion ...
n. the appearance of calcific material in joint cartilage, most commonly an incidental finding on X-ray of the knees in elderly patients and usually causing no symptoms. It is also seen less commonly in several disorders, including Wilsons disease, pseudogout, hyperparathyroidism, hypothyroidism, and haemochromatosis. ...
Diagnosis Code M11.129 information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
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New research findings reveal that Raman spectroscopy (RS) used at point of service could reduce the need for inpatient admission in patients with gout and pseudogout.
All clinicians know about the complexity in diagnosing rheumatoid arthritis (RA), especially early in the disease. Because RA lacks pathognomonic features - that is, there are no clinical, biological, or radiological characteristics specific to RA diagnosis - doubt about the diagnosis may persist for some patients1,2. Examples are patients with "nude" polyarthritis [i.e., without positivity for serum rheumatoid factor (RF), anti-citrullinated peptide antibodies, typical erosion, or all 3], or even elderly people with erosive RF-positive polyarthritis associated with psoriasis or calcium crystal deposition disease features seen on joint radiography. When RA is neither obvious nor completely excluded, the clinician strikes a balance between possible or probable RA, depending on the level of confidence. In this context, in clinical research, RA classification criteria may be of some help because they ensure, at the group level, the diagnosis of RA with minimal error. However, in clinical practice, ...
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The distal tibio-fibular joint ( DTFJ) be an integral part of the ankle and its injury makes all the gravity, forecast and complexity of ankle fracture treatment. Its classically described and known by radiological point of view, but in static incidence and from anatomical studies. To our knowledge the dynamic dimension and its modelling is missing. Our study will use high spatial-resolution MRI acquisition to obtain the best possible definition of DTFJ but especially it will be associated with MRI acquisition in movement, using typical fast sequences TrueFISP and FLASH which will allow a precise modelling of joint physiological movements and biomechanics on healthy subjects by a not invasive method. This analysis will be made on a simple movement of flexion and extension, the other possible movements of the ankle being blocked what corresponds to the clinical situation of an osteosynthesis ankle immobilized in post-operative by a dynamic rehabilitation shoe Axmed ® It will be associated ...
Klasszikus Bartter-szindr ma: Csecsem illetve fiatal gyermekkorban kezd d polydipsia, polyuria, nycturia, generaliz lt izomgyenges g, izomg rcs k s n veked si retard ci jellemzi. Pseudo-Bartter-szindr ma: Diuretikum abusus eset n kialakul , a klasszikus Bartter-szindr m hoz megt veszt sig hasonl t t netegy ttes. Gitelman-szindr ma: Enyh bb klinikai t netek, leggyakrabban gyermek s fiatal feln tt korban jelentkezik hypokaliaemia t neteivel. Az izomgyenges gen k v l hypomagnesaemi s izomg rcs k s chondrocalcinosis miatti iz leti f jdalmak l pnek fel. Jellemz je m g: hypocalcaemia, alkalosis, tetania. Antenatalis Bartter-szindr ma (hyperprostaglandin-E szindr ma): Renalis, tubularis, hypokalaemi s alkalosis s k vetkezm nyes sziszt m s k rosod sok jellemzik. T pusos t nete a magzati polyuria miatt kialakul hydramnion. Gyakran fordul el korasz l s ...
Learn more about Calcium Pyrophosphate Dihydrate Deposition Disease at Medical City Dallas DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Calcium deposition is often seen at the triangular fibrocartilage of the wrist. Subchondral sclerosis, joint space narrowing, subchondral cyst formations which may be quite large, and intraarticular bodies from subchondral osseous collapse and fragmentation are all findings which can be seen in patients with CPPD disease. These radiographic abnormalities are most common at the radiocarpal articulation and at the 2nd and 3rd metacarpophalangeal joints. Additionally, there may a shift in the normal alignment of the scaphoid and lunate and narrowing at the midcarpal compartment. Differential Diagnosis:. CPPD disease causes destruction of cartilage which can lead to radiographic findings similar to osteoarthritis. Sites of involvement are useful for differentiating the two since the radiocarpal compartment of the wrist is not a common location for osteoarthritis. Lack of an erosive process at the MCP joint differentiates CPPD crystal deposition disease from rheumatoid arthritis. Greater propensity ...
Milwaukee shoulder syndrome (apatite-associated destructive arthritis) is a rheumatological condition similar to calcium pyrophosphate dihydrate deposition disease (CPPD). It is associated with periarticular or intraarticular deposition of hydroxyapatite crystals. Crystal deposition in the joint causes the release of collagenases, serine proteases, elastases, and interleukin-1. This precipitates acute and rapid decline in joint function and degradation of joint anatomy. Subsequently disruption of the rotator cuff ensues. Along with symptomatology, the disease typically presents with positive radiologic findings, often showing marked erosion of the humeral head, cartilage, capsule, and bursae. Though rare, it is most often seen in females beginning in their 50s or 60s. Diagnosis is made with arthrocentesis and Alizarin Red staining along with clinical symptoms. Signs and symptoms may include the following: Limited active range of motion, usually unrestricted passive range of movement (early) ...
Support group for people who have Angiomyolipoma and experience Calcium Pyrophosphate Dihydrate Deposition Disease, created by eHealthMe (http://www.eHealthMe.com). To join the group, do any of these: create a post to introduce yourself, ask a question, or simply follow the group.. submitted on 6 months 1 week ago by eHealthMe.com ...
Osteoarthritis is a common feature, most often affecting the knees, shoulders, hips, and hands. Single or multiple joints may be affected. Hypertrophy of cartilage initially produces radiographic widening of the joint space. The newly synthesized cartilage is abnormally susceptible to fissuring, ulceration, and destruction. Ligamental laxity of joints further contributes to the development of osteoarthritis. Cartilage degrades, the joint space narrows, and subchondral sclerosis and osteophytes develop. Joint examination reveals crepitus and laxity. Joint fluid is noninflammatory. Calcium pyrophosphate dihydrate crystals are found in the cartilage in some cases of acromegaly arthropathy and, when shed into the joint, can elicit attacks of pseudogout. Chondrocalcinosis may be observed on radiographs. Back pain is extremely common, perhaps as a result of spine hypermobility. Spine radiographs show normal or widened intervertebral disk spaces, hypertrophic anterior osteophytes, and ligamental ...
Methods A web-based exercise and subsequent patient-based exercise were carried out. A panel of 30 OMERACT members, participated at the web-based exercise by evaluating twice a set of US images for the presence/absence of CPPD. Afterwards, 19 members of the panel met in Siena, Italy, for the patient-based exercise. During the exercise, all sonographers examined twice eight patients for the presence/absence of CPPD at the same joints. Intraoberserver and interobserver kappa values were calculated for both exercises. ...
Mg is a divalent cation mostly located intracellularly. It plays an important role in enzymatic processes. In healthy individuals homeostasis of Mg is regulated effectively, as sufficient mechanisms in the gastrointestinal tract and the kidney exist. However, if these mechanisms are affected in underlying disease, Mg depletion can cause a wide range of symptoms such as neuromuscular manifestations (muscular cramps, vertigo, tetany), cardiac and vascular manifestations (arrhythmias, hypertension), metabolic sequels and psychiatric manifestations (depression, fatigue) [11, 12].. As seen in this case, severe Mg depletion resulted in CPPD deposition with clinical manifestations of chronic inflammatory arthritis [13-16] and was responsible for muscular weakness, fatigue and the depressive episode.. Chondrocalcinosis, is defined as the deposition of calcium pyrophosphate dihydrate in hyaline or fibrous cartilage [14]. In radiography delicate linear calcification of the cartilage can be seen. The ...
Precipitation of crystals of calcium pyrophosphate dihydrate (CPP) in connective tissues may be asymptomatic or may be associated with several clinical syndromes. These disorders, including acute inflammatory, chronic inflammatory, and degenerative a
Iron was readily demonstrated in chondrocytes in 3 of 4 hemochromatosis articular cartilages studied. Either apatite, calcium pyrophosphate dihydrate crystals, or both were found in all cartilages including those of 3 patients who had no radiographic or light microscopic evidence of calcification. These crystals, which may be secondary to degenerative changes or may play a role in cartilage degeneration, were not seen in any consistent morphologic relationship with the iron deposits. In fact, apatite was found in one cartilage in which no iron was identified in the sections studied. If iron, as demonstrated in the chondrocytes, is contributing to the calcium crystal deposition, it would most likely do so indirectly, for example by altering chondrocyte enzymes or connective tissue components.
Psuedogout, also referred to as calcium pyrophosphate deposition disease, or CPDD, is a form of arthritis caused by crystal deposits in joints. The American College of Rheumatology states there is no...
Rheumatoid Arthritis is an auto-immune disease in which our immune system mistakenly attacks healthy joint tissue. It causes swelling, pain and eventually joint deformities. The inflammation can spread to the surrounding tissues and damage cartilage and bones. About 21 million people are affected by this disease globally each year.. Gout & Calcium Pyrophosphate Deposition Disease (CPPD) are caused by excess uric acid and calcium salt respectively, forming crystals in joints and causing inflammation, redness and swelling. Causes are unclear, but the risk increases with age and the disease is often misdiagnosed as arthritis. ...
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Many crystals have been associated with arthropathies or periarticular syndromes: only monosodium urate monohydrate (gout), calcium pyrophosphate dehydrate (pseudogout, chondrocalcinosis), and basic calcium phosphates (mainly hydroxyapatite) are common.Crystals implicated in joint disease are stable, hard particles that exert biological effects via surface-active (activation of humoral and cell-derived mediators, interaction with cell membranes) and mechanical properties. In general, smaller particle size, marked surface irregularity, and high negative surface charge correlate with inflammatory potential....
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If the skin over the joint is hot and red, and the pain comes in repeated attacks, the cause is likely to be either gout or pseudogout.. Both of these are types of arthritis. Gout usually affects the joint of the big toe first before affecting other joints. Its important to correctly diagnose gout, as treatment will prevent future attacks of joint pain and disability.. Pseudogout is similar to gout, but usually affects the knee joint first.. See your GP if you think you have gout or pseudogout.. ...
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Background. There are few data on anakinra use after failure of conventional medications for crystal-induced peripheral arthritis and/or crowned dens syndrome among complex hospitalized patients. Methods. We retrospectively analyzed the outcome of six patients affected with subacute crystal-induced arthritis who had received anakinra in second or third line therapy, including three patients with crowned dens syndrome and three others with gouty arthritis. Patients comorbidities, reasons for anakinra use and associated drugs, and outcomes were recorded. Results. All patients presented with elevated inflammatory syndrome, systemic symptoms with poly/oligoarthritis. Except for absolute contraindications, all patients were previously treated with full or decreased dose of NSAID, colchicine, and/or glucocorticoids, with unsatisfactory response. All three gouty patients exhibited complete responses in all acute involvements under anakinra within 3 to 5 days, including one of them who needed the
The deposit of uric crystals is one of the complications that you can have when suffering from gout. These tophi get formed in the joints of your hands and feet. This gout complication usually causes deformities, damage the tissue that surrounds the area of the gout. As a result you might suffer from destruction of your joint, constant pain and more worse, compression of your nerves. This is just one of the many gout effects. It takes about ten years for a gout patient to develop a chronic gout stage. At this stage, the gout has already cause serious damage to your joints. Of course, we are talking about the joints that have been affected by the gout. Furthermore, at this stage, some damage to your kidneys may have also been cause by the gout. More than half of the gout patients that have reached this stage also suffer from tophi, which are crystals of uric acid. Studies show that a number of three gout patient out of four suffer from tophi by the time they have reached the twentieth year of ...
Heritage, Hippocrates has been basically one among the very first customer to try to define or explain precisely what instigated gout. Its recognized that back within the 400 B.C. Hippocrates reasoned that gout had been connected for the four humors in your body. They belief that in case every one of the four humors were absolutely suppose for being balanced healthy to create good wellness and also in case it had become unbalanced after that that delivered disease for the body system. The 4 Humours have been nothing yet the blood, phlegm, the yellow bile and the african american bile. He thought that main motive of Gout was the excessive of one of these four humors. He believed that if you experience the surplus of this and in case put towards the joint elements this may cause undesired soreness and also bloating or irritation ...
If the skin over the joint is hot and red, and the pain comes in repeated attacks, the cause is likely to be either gout or pseudogout.. Both conditions are types of arthritis. Gout usually affects the joint of the big toe first, before affecting other joints. Its important to correctly diagnose gout, as treatment will prevent future attacks of joint pain and disability.. Pseudogout is a similar condition to gout, but usually affects the knee joint first.. See your GP if you think you have either condition.. ...
hi doctor. Ive been getting a lot of pain in my feet and my girlfriend thinks it is gout. what should I do to treat it? also, I know that there are dietary changes to be made, but I eat healthy foo...
Like you, I become interested in medical astrology from time to time on an as needs basis. Unless you are a full-time astrologer, the strict rules of decumbiture provide examples only occasionally. I tend to rely on times provided by friends of mine having a medical crisis. This isnt a very systematic way of studying decumbiture, but over the past few months several of my close friends have experienced illnesses resulting in need for bed rest, ER visits, etc. So I will try to get a few more permissions to post decumbiture charts from these folks for discussion here ...
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Fluid accumulated in the knee of a patient causes pain in the joints. Joint aspiration is a procedure that is conducted to remove this fluid from the knee of the patient. It is usually conducted in patients suffering from arthritis.
... is a procedure to remove fluid from the space around a joint using a needle and syringe. It may be done to relieve swelling and/or to obtain fluid for analysis to diagnose a joint disorder and/or problem.
Care guide for Joint Aspiration. Includes: possible causes, signs and symptoms, standard treatment options and means of care and support.
AA (Inflammatory) AmyloidosisDiabetic NephropathyFamilial Renal AmyloidosisIgA NephropathyImmunoglobulin-Related AmyloidosisLight Chain-Associated Renal DisordersMultiple MyelomaNephrotic Syndrome
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WHAT: Haemochromatosis: Haemochromatosis: a disorder of iron metabolism characterized by excess deposition of iron in the tissues, especially the liver. It is characterized by pigmentation of the skin, hepatic cirrhosis, decreased carbohydrate tolerance, cardiomyopathy and endocrinopathy (especially hypogonadism). Mainly seen in men over the age of 40 years. It has an associated arthropathy distinguished by involvement of the metacarpophalangeal joints (particularly the second and third), wrists, knees, shoulders, and hips. There is often an associated chondrocalcinosis. WHY: Haemochromatosis is an autosomal recessive disease that produces an arthritis similar to osteoarthritis or pseudogout. HOW: Haemochromatosis is diagnosed by the typical physical and radiographic findings supported by elevated serum iron concentrations and high transferrin saturations. Serum ferritin is also markedly elevated. Confirmation of the diagnosis can be done by demonstrating hepatic iron deposition on liver biopsy. ...
Chronic CPP crystal inflammatory arthritis: Chronic inflammatory oligoarthritis or polyarthritis associated with CPPD. Patients have occasional systemic upset with elevation of CRP and ESR and superimposed flares with characteristics of crystal inflammation (see above). Differential considerations include rheumatoid arthritis and other chronic inflammatory joint diseases in older adults. Imaging findings are similar to those of osteoarthritis, but the dirstribution within the joint is different, with CPPD affecting non-weight-bearing surfaces of joints. It is also usually bilateral and symmetric. Synovial inflammation and joint effusions can also be seen. Osteophytes and osteochondral bodies are commonly present. Subchondral cysts are more prominent than in osteoarthritis, and may form before cartilage loss is radiographically evident. Risk factors for calcium pyrophosphate arthropathy are aging, osteoarthritis, previous joint trauma, metabolic diseases (e.g., the four Hs: hemochromatosis, ...
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Connective Tissue Gene Tests Abnormal mineralization disorders NextGen sequencing panel consists of fifteen genes associated with abnormal mineralization. The panel includes hypophosphatasia, chondrocalcinosis, CASR-related disorders, and autosomal dominant, autosomal recessive and X-linked forms of rickets.. The Abnormal mineralization disorders NGS panel consists of fifteen genes: ALPL, ANKH, CASR, CLCN5, CYP27B1, DMP1, ENPP1, FAH, FGF23, OCRL, PHEX, SLC34A1, SLC34A3, SLC9A3R1 and VDR.. Copy number variation (CNV) analysis of the Abnormal mineralization disorder genes is also offered as a panel. Additionally, CTGT offers a comprehensive test (both NGS and CNV panels) for these genes. Panel genes are also offered as individual sequencing and deletion/duplication tests unless otherwise indicated.. ...
Familial hypocalciuric hypercalcemia (HHC) is a heritable disorder of mineral homeostasis that is transmitted as an autosomal dominant trait with a high degree of penetrance. HHC is characterized biochemically by lifelong elevation of serum calcium concentrations and is associated with inappropriately low urinary calcium excretion and a normal or mildly elevated circulating parathyroid hormone (PTH; {168450}) level. Hypermagnesemia is typically present. Individuals with HHC are usually asymptomatic and the disorder is considered benign. However, chondrocalcinosis and pancreatitis occur in some adults (summary by {17:Hannan et al., 2010 ...
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Gout is a disease in which there is a buildup of uric acid, formed into crystals, which get deposited in the cartilage of joints or tendons, and even surrounding tissue.?? This causes these areas of the body to become inflamed and swollen, as with other forms of arthritis.?? While gout can really occur in any joint of the body, it usually attacks the big toe first, followed by the ankle, heel, knee, wrist, elbows, and even the spine.?? It may seem even a bit laughable to think of an inflammation of the big toe as something that needs to be taken seriously, but in reality gout is a very painful disease.?? It is usually accompanied by a burning sensation, swelling, stiffness, and a warmness of the affected area.?? Typically the patient also has a low-grade fever that lasts longer than it should.?? Many who suffer from gout even in its most minor form find that any contact of the affected area, such as with an article of clothing, can be excruciating ...
A few months ago I rather suddenly developed an acute painful swelling at the base of my left big toe. "I think Im having an attack of gout, but why me?" I wondered. Of course this had to happen on a weekend, when the Family Practice Clinic Id usually go to was closed, as was my Podiatrists office.. I wondered if I could have septic arthritis, an infected joint, but had no obvious reason for this much more frightening diagnosis. I remembered there was also an entity called pseudogout, where the crystals were calcium pyrophosphate, not uric acid.. So I went to the Urgent Care Center our local hospital established a few blocks away from my house. A Family Practice physician examined me and said, "I think you have gout, but youll need to go to the hospitals Emergency Department (ED) so they can get some fluid from your joint and decide if its really gout. We dont do that test here." She was also concerned about the rather slim possibility of septic arthritis.. At the ED I was triaged as ...
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Light-chain deposition disease (LCDD) is the deposition of monoclonal light chains in multiple organs. It is a rare disease characterized by deposition of nonamyloid immunoglobulin light chains, and they do not stain with Congo red and do not exhibit a fibrillar structure when examined ultrastructurally.
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Adenosine-5-diphosphoribose sodium salt dihydrate;68414-18-6;Adenosine-5-diphosphoribose sodium salt dihydrate;TS84182.Tetrahedron
Joint aspiration refers to removing fluid from the space around a joint using a needle and syringe. This is usually performed under a local anesthetic to either relieve swelling or to obtain fluid for analysis to diagnose a joint disorder and/or problem.. Joint aspiration is usually performed on the knee. However, fluid can also be removed from other joints, such as the hip, ankle, shoulder, elbow, or wrist.. Other related procedures that may be used to help diagnose joint problems include X-ray, bone scan, magnetic resonance imaging (MRI), computed tomography (CT scan), arthroscopy, and arthrography. Please see these procedures for additional information.. ...
WebMD Symptom Checker helps you find the most common medical conditions indicated by the symptoms Joint instability, Joint pain, Lump or bulge and Swelling and including Osteoarthritis, ACL knee injury and Pseudogout.
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C~0H~gN5Os.2H20, Mr=325.32, monoclinic,P2~, a = 12.029 (2), b=4.904 (2), c=13.215 (2) A, fl= 107.68 (2) ° , F= 743 (1) A 3, Z= 2,D m = 1-45, D x = 1.45 Mg m -3, Cu Ka, 2 = 1.54184 A,fl= 1.01mm -1, F(000)=348, T=293K. The final R value for 1277 observed reflections 110 ,_ 3tr(Io)l is 0.031. The dipeptide exists as a zwitterion. The arginyl side-chain conformation is similar to that found in arginyl-glutamic acid [Pandit, Seshadri & Viswamitra (1983). Acta Cryst. C39, 1669-16721. The guanidyl group forms a pair of hydrogen bonds with oxygen atoms of the backbone carboxyl group. The crystal structure is also stabilized by -bonding interactions involving both water molecules.. ...
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Diabetes mellitus is a common metabolic disease; prevalent word wide can be associated with variety of musculoskeletal manifestations. They may be classified as articular, nonarticular and bony conditions. Among articular conditions, osteoarthritis is frequent and early in diabetes, in which also chondrocalcinosis and gout occur. Diabetic cheiroarthropathy, neuropathic arthritis, diabetic amyotrophy, diabetic muscle infarction are considered to be non-articular conditions. Among bone conditions, osteopenia and osteoporosis may occur early in type 1 diabetes. This article reviews clinical, diagnostic and therapeutic aspects of these conditions.. ...
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TY - JOUR. T1 - Long-Term Outcome of Renal Transplantation in Light-Chain Deposition Disease. AU - Leung, Nelson. AU - Lager, Donna J.. AU - Gertz, Morie. AU - Wilson, Kirk. AU - Kanakiriya, Sharan. AU - Fervenza, Fernando Custodio. PY - 2004/1. Y1 - 2004/1. N2 - Background: Light-chain deposition disease (LCDD) is a monoclonal gammopathy characterized by nonamyloid deposition of light chain in various organs. A small number of kidney transplantations have been performed on LCDD patients in whom end-stage renal disease (ESRD) developed. Methods: The authors retrospectively reviewed the clinical and histologic findings and outcome of 7 patients with LCDD who underwent kidney transplantation at our institution. Results: Renal insufficiency, hypertension, and proteinuria were present in all 7 patients. Proteinuria level was greater than 3.5 g/24 h in 3 patients. Three patients had microscopic hematuria. Monoclonal protein was detected in the serum in 3 patients, urine in 5, and was undetectable in ...
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LIPA Chondrocalcinosis 2; 118600; ANKH Chondrodysplasia punctata, rhizomelic, type 2; 222765; GNPAT Chondrodysplasia punctata, ...
"ATP-induced chondrocalcinosis". Arthritis Rheum. 35 (12): 1520-5. doi:10.1002/art.1780351216. PMID 1472129. Heptad Repeat 2 in ...
1996). "Localisation of a gene for chondrocalcinosis to chromosome 5p". Hum. Mol. Genet. 4 (7): 1225-8. doi:10.1093/hmg/4.7. ... 2002). "Mutations in ANKH cause chondrocalcinosis". Am. J. Hum. Genet. 71 (4): 933-40. doi:10.1086/343054. PMC 378546 . PMID ... 2000). "Physical map and characterization of transcripts in the candidate interval for familial chondrocalcinosis at chromosome ...
Pain, swelling, or stiffness in one or more joints is commonly present in psoriatic arthritis.[4] Psoriatic arthritis is inflammatory, and affected joints are generally red or warm to the touch.[4] Asymmetrical oligoarthritis, defined as inflammation affecting one to four joints during the first six months of disease, is present in 70% of cases. However, in 15% of cases, the arthritis is symmetrical. The joints of the hand that is involved in psoriasis are the proximal interphalangeal (PIP), the distal interphalangeal (DIP), the metacarpophalangeal (MCP), and the wrist. Involvement of the distal interphalangeal joints (DIP) is a characteristic feature and is present in 15% of cases. In addition to affecting the joints of the hands and wrists, psoriatic arthritis may affect the fingers, nails, and skin. Sausage-like swelling in the fingers or toes, known as dactylitis, may occur.[4] Psoriasis can also cause changes to the nails, such as pitting or separation from the nail bed,[4] onycholysis, ...
712.1) Chondrocalcinosis due to dicalcium phosphate crystals. *(712.2) Chondrocalcinosis due to pyrophosphate crystals ...
Haemochromatosis arthropathy includes degenerative osteoarthritis and chondrocalcinosis. The distribution of the arthropathy is ...
Chondrocalcinosis (pseudogout). References[edit]. *^ Edwards, N. Lawrence (2008). Primer on the Rheumatic Diseases: Chapter 12 ...
At ultrasound, chondrocalcinosis may be depicted as echogenic foci with no acoustic shadow within the hyaline cartilage. As ... Radiology has a large role to play in finding chondrocalcinosis, with radiographs, CT scans, MRIs, US, and nuclear medicine all ... Free chapter on acromioclavicular chondrocalcinosis is available at ShoulderUS.com Hosler, Greg. "calcinosis_cutis_2_060122". ... Chondrocalcinosis, on the other hand, refers to the radiographic evidence of calcification in hyaline and/or fibrocartilage. " ...
"A gain of function mutation in TNFRSF11B encoding osteoprotegerin causes osteoarthritis with chondrocalcinosis". Annals of the ...
Overactivity of the enzyme is associated with chondrocalcinosis, while deficiency correlates to pathological calcification. ...
Free chapter on acromioclavicular chondrocalcinosis is available at ShoulderUS.com *^ Hosler, Greg. "calcinosis_cutis_2_060122" ... Medical imaging, consisting of x-ray, CT, MRI, or ultrasound may detect chondrocalcinosis within the affected joint, indicating ... X-ray, CT, or other imaging usually shows accumulation of calcium within the joint cartilage, known as chondrocalcinosis. There ... Chondrocalcinosis,[2][3] on the other hand, refers to the radiographic evidence of calcification in hyaline and/or ...
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... chondrocalcinosis MeSH C05.550.114.423 --- gout MeSH C05.550.114.423.410 --- arthritis, gouty MeSH C05.550.114.606 --- ...
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X-rays will also show bone features of renal osteodystrophy (subperiostic bone resorption, chondrocalcinosis at the knees and ...
In some cases, arthritis from injury can cause chondrocalcinosis. Other causes of chondrocalcinosis include: Hypercalcaemia, ... Chondrocalcinosis is calcification in hyaline and/or fibrocartilage. It can be seen on radiography. A common cause of ... At ultrasound, chondrocalcinosis may be depicted as echogenic foci with no acoustic shadow within the hyaline cartilage. As ... "Chondrocalcinosis". Radiopedia. Retrieved 2017-08-11. CS1 maint: Explicit use of et al. (link) de Filippi JP, Diderich PP, ...
Encouraging the use of proper ergonomics not only includes matching the physical ability of the worker with the correct job, but it deals with designing equipment that is correct for the task.[23] Limiting heavy lifting, training, and reporting early signs of injury are examples that can prevent MSD.[24] Employers can provide support for employees in order to prevent MSD in the workplace by involving the employees in planning, assessing, and developing standards of procedures that will support proper ergonomics and prevent injury.[24] One focus of ergonomic principles is maintaining neutral postures, which are postures in which muscles are at their normal length and able to generate the most force, while reducing stress and possible injury to muscles, tendons, nerves, and bones- therefore, in the workplace or in everyday life, it is ideal for muscles and joints to maintain neutral positions.[25] Additionally, to prevent hand, wrist, and finger injuries, understanding when to use pinch grips ...
Metabolic disease (gout, chondrocalcinosis). *Capsulitis, synovitis. *Ankylosis (fibrous or bony). *Fracture. *Absent, large, ...
In pseudogout/chondrocalcinosis/calcium pyrophosphate deposition disease, the crystal is calcium pyrophosphate. Diabetic ...
chondrocalcinosis. Until now, the diagnosis of calcium pyrophosphate dihydrate (CPPD) crystal deposition disease has been based ... Knee chondrocalcinosis. An ultrasonographic study of the hyaline cartilage. J Clin Imag2002;26:194-6. ... Coari G, Iagnocco A, Zoppini A. Chondrocalcinosis: sonographic study of the knee. Clin Rheumatol1995;14:511-14. ... Kellner H, Zoller W, Herzer P. Ultrasound findings in chondrocalcinosis. Z Rheumatol1990;49:147-50. ...
Free chapter on acromioclavicular chondrocalcinosis is available at ShoulderUS.com *^ Hosler, Greg. "calcinosis_cutis_2_060122" ... Medical imaging, consisting of x-ray, CT, MRI, or ultrasound may detect chondrocalcinosis within the affected joint, indicating ... X-ray, CT, or other imaging usually shows accumulation of calcium within the joint cartilage, known as chondrocalcinosis. There ... Chondrocalcinosis,[2][3] on the other hand, refers to the radiographic evidence of calcification in hyaline and/or ...
Chondrocalcinosis: Generally an incidental radiographic finding, chondrocalcinosis is usually seen in asymptomatic individuals ... Chondrocalcinosis: Calcification of articular cartilage (identified by x-ray).. -Chronic CPPD crystal deposition disease: ... Synonyms: Pseudogout, chondrocalcinosis, pyrophosphate arthropathy.. ICD-9 Codes: Pseudogout, 712.2; CPPD crystal deposition ... Pseudogout: The presence of an acute synovitis in one or a few joints, with radiographic chondrocalcinosis and/or synovial CPPD ...
In some cases, arthritis from injury can cause chondrocalcinosis. Other causes of chondrocalcinosis include: Hypercalcaemia, ... Chondrocalcinosis is calcification in hyaline and/or fibrocartilage. It can be seen on radiography. A common cause of ... At ultrasound, chondrocalcinosis may be depicted as echogenic foci with no acoustic shadow within the hyaline cartilage. As ... "Chondrocalcinosis". Radiopedia. Retrieved 2017-08-11. CS1 maint: Explicit use of et al. (link) de Filippi JP, Diderich PP, ...
Articular chondrocalcinosis definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation ... articular chondrocalcinosis in Medicine Expand. articular chondrocalcinosis n. A disease characterized by deposits of calcium ...
Preliminary Diagnosis: Chondrocalcinosis. I. What imaging technique is first-line for this diagnosis?. *. Plain radiographs ... V. Describe the advantages and disadvantages of the alternative techniques for diagnosis of chondrocalcinosis. * CT scan ... Describe the advantages and disadvantages of this technique for diagnosis of chondrocalcinosis.. Advantages. *. May be ... V. Describe the advantages and disadvantages of the alternative techniques for diagnosis of chondrocalcinosis.. CT scan without ...
Chondrocalcinosis: Presence of calcium salts, especially calcium pyrophosphate, in the cartilaginous structures of one or more ... Chondrocalcinosis (Pseudogout). Subscribe to New Research on Chondrocalcinosis Presence of calcium salts, especially calcium ... 05/01/2014 - "[Chondrocalcinosis due to calcium pyrophosphate deposition (CPPD). ". 01/01/2014 - "Chondrocalcinosis (CC) most ... "Efficacy of anakinra in articular chondrocalcinosis".". 05/01/2012 - "Efficacy of anakinra in articular chondrocalcinosis: ...
Chondrocalcinosis secondary to hypomagnesemia in Gitelmans syndrome.. Hang-Korng Ea, Anne Blanchard, Maxime Dougados, ... Chondrocalcinosis secondary to hypomagnesemia in Gitelmans syndrome.. Hang-Korng Ea, Anne Blanchard, Maxime Dougados, ... Chondrocalcinosis secondary to hypomagnesemia in Gitelmans syndrome. Message Subject (Your Name) has forwarded a page to you ... Chondrocalcinosis secondary to hypomagnesemia in Gitelmans syndrome.. Hang-Korng Ea, Anne Blanchard, Maxime Dougados and ...
Proceedings: A study of the incidence of articular chondrocalcinosis in Pagets disease of bone. ... Proceedings: A study of the incidence of articular chondrocalcinosis in Pagets disease of bone. ... Proceedings: A study of the incidence of articular chondrocalcinosis in Pagets disease of bone. ...
Radiographic knee chondrocalcinosis was present if there was definite linear cartilage calcification. Serum magnesium ... Subjects with lower levels of serum magnesium, even within the normal range, had higher prevalence of knee chondrocalcinosis in ... The prevalence of knee chondrocalcinosis was 1.4% in the Xiangya Hospital Health Management Center Study (n = 12,631). Compared ... We examined the relation of serum magnesium levels to prevalence of knee chondrocalcinosis using generalized estimating ...
In need of more information about this disease if anyone has it. I am waiting for my informational appt with my doctor but am looking for info in the meantime. Questions are: what is prognosis? How does disease usually progress? DOES it usually spread to other joints, or is it impossible to know for sure if it wiil? Is it the same as pseudogout and CPPD or just associated with them..how does it differ? Is it a rheumatological disease or metabolic? Ive heard it described as both and Im not sure what the difference is. Thanks to anyone that can help me while I wait to see my doctor!. Reply Follow This Thread Stop Following This Thread Flag this Discussion ...
In chondrocalcinosis, also called CPPD, calcium crystals build up in joint cartilage, causing symptoms that resemble ... Chondrocalcinosis, more formally known as calcium pyrophosphate dihydrate deposition disease (CPPD), is a condition in which ...
Chondrocalcinosis is a rheumatologic condition that is characterized by accumulation of calcium pyrophosphate dihydrate ... Chondrocalcinosis Prognosis. As aforesaid, Chondrocalcinosis is often left untreated if there is no pain. In case a patient is ... Picture 1 - Chondrocalcinosis Chondrocalcinosis is mostly seen in aged patients as an increased accumulation of CPPD crystals ... Chondrocalcinosis Treatment. Chondrocalcinosis is not treated if it does not causeany pain. This is because any medications ...
Investigation of the role of ENPP1 and TNAP genes in chondrocalcinosis A rare case of chondrocalcinosis in the left sterno- ... Comparison of three imaging techniques in diagnosis of chondrocalcinosis of the knees in calcium pyrophosphate deposition ...
Familial chondrocalcinosis of left hand. ICD-10-CM M11.142 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0): *553 ... Familial chondrocalcinosis, left hand. 2016 2017 2018 2019 2020 Billable/Specific Code *M11.142 is a billable/specific ICD-10- ...
The workmens comp dr concluded it was a condition call chondrocalcinosis and signed me off workmenscomp. Any ideas? ... I fell got pinched nerve a work, the dr concluded it was chondrocalcinosis. Any ideas?. ...
There are two forms of chondrocalcinosis: primary chondrocalcinosis and secondary chondrocalcinosis.. Primary chondrocalcinosis ... It is called secondary chondrocalcinosis when it is the consequence of a pre-existing disease. This form of chondrocalcinosis ... In case of primary chondrocalcinosis, chondrocalcinosis mainly affects the elderly, its frequency increasing with age. It ... The frequency of chondrocalcinosis increases with age: it never appears before the age of 30, and usually after the age of ...
Chondrocalcinosis / pyrophosphate crystal arthritis forms calcifications in articular cartilage, meniscus and intervertebral ... Blood tests for chondrocalcinosis. *In case of acute attacks of chondrocalcinosis, CRP and the Sedimentation rate increase at ... The incidence of chondrocalcinosis increases with age and is rare before 40 years of age. Among people over 85 years, ... Chondrocalcinosis of the knee with calcification in meniscus (a) and meniscus injury (b). Bolog NV, Andreisek G - Insights ...
... me about it and it sounds like it is something called either calcium oxalate associated arthritis or calcium chondrocalcinosis ...
Chondrocalcinosis. Chondrocalcinosis is calcification of the menisci, synovium, and/or articular cartilage due to the ... Effect of chondrocalcinosis on the MR imaging of knee menisci. AJR Am J Roentgenol. 2001 Oct. 177(4):905-9. [Medline]. ... The presence of chondrocalcinosis can result in a false-positive diagnosis of a meniscal tear. View Media Gallery ... Chondrocalcinosis mimicking a meniscal tear on MR imaging. AJR Am J Roentgenol. 1998 Jan. 170(1):69-70. [Medline]. ...
Chondrocalcinosis of the knee refers to the presence of calcium crystals inside the knee joint. In general both knees are ... Chondrocalcinosis of the knee refers to the presence of calcium crystals inside the knee joint. In general both knees are ... This document, titled Chondrocalcinosis of the knee - Definition, is available under the Creative Commons license. Any copy, ...
... and 20 knees with degenerative arthritis and chondrocalcinosis, as proven histologically. The survival rates were not ... The presence of chondrocalcinosis in a knee which otherwise fulfils the criteria for unicompartmental knee arthroplasty has ... Chondrocalcinosis and medial unicompartmental knee arthroplasty Woods DA., Wallace DA., Woods CG., McLardy-Smith P., Carr AJ., ... The presence of chondrocalcinosis in a knee which otherwise fulfils the criteria for unicompartmental knee arthroplasty has ...
This mnemonic has been commonly used to recall the differential diagnosis of chondrocalcinosis, the most common cause of which ... Chondrocalcinosis Mnemonic - WHIP A DOG. Posted by radiologypics ⋅ March 27, 2013. ⋅ Leave a comment ... This mnemonic has been commonly used to recall the differential diagnosis of chondrocalcinosis, the most common cause of which ...
Medigest has all you need to know about Chondrocalcinosis - Symptoms and Signs, Causes, Treatments and definition ... Chondrocalcinosis Below you will find more information about Chondrocalcinosis from Medigest. If you believe that you are ... Discuss Chondrocalcinosis in our forums Discuss Chondrocalcinosis with other members of Medigest in our forums. ... Chondrocalcinosis can cause crystal-induced synovitis due to the shedding of crystals in the space once occupied by a CPPD ...
Short Description: Familial chondrocalcinosis, unspecified elbow Long Description: Familial chondrocalcinosis, unspecified ...
  • If you believe that you are suffering from any of the symptoms of Chondrocalcinosis it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. (medigest.uk)
  • There are medical conditions that carry similar symptoms associated with Chondrocalcinosis and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. (medigest.uk)
  • In addition, people with chondrocalcinosis 2 are more likely to have symptoms that develop earlier in adulthood than the age-related form. (cdc.gov)
  • Some people with chondrocalcinosis 2 may not have any symptoms of the disease other than showing calcium deposits in and around joints on X-rays . (cdc.gov)
  • Chondrocalcinosis of the knee refers to the presence of calcium crystals inside the knee joint. (ccm.net)
  • The main objective of treating chondrocalcinosis is by preventing the spread of crystals in the joints. (medigest.uk)
  • Crystals tend to develop in the joints and is diagnosed after having joint fluids observed under a microscope, and the ones found in the cartilage is called chondrocalcinosis. (medigest.uk)
  • X-rays will also show bone features of renal osteodystrophy (subperiostic bone resorption, chondrocalcinosis at the knees and pubic symphysis, osteopenia and bone fractures) but may be difficult to differentiate from other conditions. (wikipedia.org)
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Chondrocalcinosis due to apatite crystal deposition. (cdc.gov)
  • Patients of Hemochromatosis are also vulnerable to the development of Chondrocalcinosis, due to high levels of iron in their tissues. (hxbenefit.com)
  • The age, sex and BMI-adjusted ORs of chondrocalcinosis were 0.67 (95% CI 0.34-1.30) in the second and 0.45 (95% CI 0.21-0.94) in the third tertile of serum magnesium when compared with the lowest tertile ( P for trend = 0.030). (biomedcentral.com)
  • However, these findings were often based on subjects with extremely low serum magnesium, and it remains unclear whether more modest variations of magnesium levels observed in the general population are associated with the prevalence of chondrocalcinosis. (biomedcentral.com)
  • The most common areas where chondrocalcinosis develops are the wrists, elbows, hips and knees. (medigest.uk)
  • Chondrocalcinosis 2 is caused by changes in the ANKH gene . (cdc.gov)
  • Radiology has a large role to play in finding chondrocalcinosis, with radiographs, CT scans, MRIs, US, and nuclear medicine all having a part. (wikipedia.org)
  • If, however, an acute attack of Chondrocalcinosis is occurring already, higher doses of NSAIDs are recommended. (hxbenefit.com)
  • Individuals affected by Gitelman's syndrome often complain of severe muscle cramps or weakness, numbness, thirst, waking up at night to urinate, salt cravings, abnormal sensations, chondrocalcinosis, or weakness expressed as extreme fatigue or irritability. (wikipedia.org)
  • Some people with chondrocalcinosis 2 may experience pain in the back if calcium deposits develop around the bones of the spine. (cdc.gov)
  • Chondrocalcinosis 2 is diagnosed based on imaging such as X-rays . (cdc.gov)
  • Dear Doctor: I was recently diagnosed with chondrocalcinosis, which is quite painful. (uexpress.com)