AnatomyDiseasesAnalytical, Diagnostic and Therapeutic Techniques and EquipmentDisciplines and OccupationsHumanitiesInformation ScienceGeographicals
ChondroblastomaCurettageFoot BonesBone Cysts, AneurysmalTemporal BoneBone NeoplasmsFemoral NeoplasmsTarsal BonesSkull NeoplasmsHumerusGiant Cell Tumor of BoneEncyclopedias as TopicShoulder FracturesBone CystsArthrodesisIlizarov TechniqueArchivesBiological Science DisciplinesPeriodicals as TopicPubMedGastroenterologyGermany
Chondroblastoma: A usually benign tumor composed of cells which arise from chondroblasts or their precursors and which tend to differentiate into cartilage cells. It occurs primarily in the epiphyses of adolescents. It is relatively rare and represents less than 2% of all primary bone tumors. The peak incidence is in the second decade of life; it is about twice as common in males as in females. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1846)Curettage: A scraping, usually of the interior of a cavity or tract, for removal of new growth or other abnormal tissue, or to obtain material for tissue diagnosis. It is performed with a curet (curette), a spoon-shaped instrument designed for that purpose. (From Stedman, 25th ed & Dorland, 27th ed)Foot Bones: The TARSAL BONES; METATARSAL BONES; and PHALANGES OF TOES. The tarsal bones consists of seven bones: CALCANEUS; TALUS; cuboid; navicular; internal; middle; and external cuneiform bones. The five metatarsal bones are numbered one through five, running medial to lateral. There are 14 phalanges in each foot, the great toe has two while the other toes have three each.Bone Cysts, Aneurysmal: Fibrous blood-filled cyst in the bone. Although benign it can be destructive causing deformity and fractures.Temporal Bone: Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull).Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Femoral NeoplasmsTarsal Bones: The seven bones which form the tarsus - namely, CALCANEUS; TALUS; cuboid, navicular, and the internal, middle, and external cuneiforms.Skull Neoplasms: Neoplasms of the bony part of the skull.Humerus: Bone in humans and primates extending from the SHOULDER JOINT to the ELBOW JOINT.Giant Cell Tumor of Bone: A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Shoulder Fractures: Fractures of the proximal humerus, including the head, anatomic and surgical necks, and tuberosities.Bone Cysts: Benign unilocular lytic areas in the proximal end of a long bone with well defined and narrow endosteal margins. The cysts contain fluid and the cyst walls may contain some giant cells. Bone cysts usually occur in males between the ages 3-15 years.Arthrodesis: The surgical fixation of a joint by a procedure designed to accomplish fusion of the joint surfaces by promoting the proliferation of bone cells. (Dorland, 28th ed)Ilizarov Technique: A bone fixation technique using an external fixator (FIXATORS, EXTERNAL) for lengthening limbs, correcting pseudarthroses and other deformities, and assisting the healing of otherwise hopeless traumatic or pathological fractures and infections, such as chronic osteomyelitis. The method was devised by the Russian orthopedic surgeon Gavriil Abramovich Ilizarov (1921-1992). (From Bull Hosp Jt Dis 1992 Summer;52(1):1)ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Gastroenterology: A subspecialty of internal medicine concerned with the study of the physiology and diseases of the digestive system and related structures (esophagus, liver, gallbladder, and pancreas).Germany

Chondroblastoma of the temporal bone: a clinicopathologic study of five cases. (1/41)

Chondroblastoma is a rare benign bone tumor. It commonly affects the epiphysis of long bones during the second and third decades of life. Chondroblastoma of the temporal bone is extremely rare. We reviewed five cases of chondroblastoma arising in the temporal bone. Four cases were female and one was male. The ages ranged from 41 to 60 years (mean, 53.6 years). All cases involved the temporal bone. Three involved the left side and two the right. Chief complaints were long-standing localized pain and hearing difficulty. A sharply demarcated lobulated mass was the main radiological finding. Microscopic findings were those of chondroblastoma of usual locations. Two cases showed aneurysmal bone cyst-like areas. Immunohistochemical studies for CD34, CD99, S-100 protein and cytokeratin were performed. Tumor cells were diffusely positive for S-100 protein in three cases and weakly positive for cytokeratin in one case. CD34 and CD99 were negative in all cases. In summary, chondroblastoma of the temporal bone is rare and occurs in older age group than reported cases of chondroblastoma of the usual location in the literature.  (+info)

Extendible replacements of the proximal tibia for bone tumours. (2/41)

Limb salvage is now customary in the treatment of primary bone tumours. The proximal tibia is a frequent site for these neoplasms but reconstruction, especially in children, is a formidable challenge. We reviewed 20 children with extendible replacements of the proximal tibia, all with a minimum follow-up of five years. Five died from their disease and, of the remaining 15, four had above-knee amputations for complications. Infection occurred in seven patients; in five it was related to the lengthening procedure. Aseptic loosening is inevitable in the younger children and only two have avoided a revision, amputation or other major complication; both were aged 12 years at the time of the initial surgery. Despite this, 11 children are alive with a functioning leg and a mean Musculoskeletal Tumour Society functional score of 83%. The lengthening mechanisms used in our series required extensive open operations. We are now using a simpler, minimally invasive, technique which we hope will decrease the incidence of complications. At present, the use of extendible prostheses of the proximal tibia remains an experimental procedure.  (+info)

h-Caldesmon as a specific marker for smooth muscle tumors. Comparison with other smooth muscle markers in bone tumors. (3/41)

Caldesmon is a protein widely distributed in smooth and non-smooth muscle cells and is thought to regulate cellular contraction. Its isoform, high-molecular-weight caldesmon (h-CD), was demonstrated to be specific for smooth muscle cells and smooth muscle tumors of the soft tissue and to never be expressed in myofibroblasts. We performed an immunohistochemical study to examine h-CD expression in the following bone tumors: conventional and non-conventional osteosarcoma, 13; malignant fibrous histiocytoma of bone, 5; giant cell tumors of bone, 5; chondroblastoma, 3; metastatic leiomyosarcoma, 2; and rhabdomyosarcoma, 1. Frequent immunoreactivity for muscle actin (alpha-smooth muscle actin or muscle-specific actin) was seen in 11 of 13 osteosarcomas and all other tumors, whereas h-CD was expressed intensely only in 2 leiomyosarcomas. h-CD is considered a specific and useful marker to distinguish smooth muscle tumor from bone tumors with myoid differentiation.  (+info)

Benign chondroblastoma of bone. Report of a case. (4/41)

A benign chondroblastoma of bone is reported. It was unusual because it occurred in an old lady, in a toe, and it was not painful and radiologically resembled a chondroma. The coarsely lobulated tumour showed a varied microscopic appearance, but it consisted chiefly of closely packed sheets of small, round polygonal or fusiform cells. There was some calcification present. The literature is reviewed.  (+info)

Chondroblastoma of a metacarpal bone mimicking an aneurysmal bone cyst: a case report and a review of the literature. (5/41)

Chondroblastoma of the metacarpal bone has been extremely rare and only seven cases have been reported in the English literature. Here we reported the eighth case of a chondroblastoma that developed on the first metacarpal bone of the right hand of a 21-year-old man. Radiographs showed an expansile osteolytic lesion with a multilocular appearance. In MR images, the lesion showed low intensity in T1 and high intensity in T2-weighted images with multiple fluid-fluid levels, which are findings resembling those of an aneurysmal bone cyst. From the pathological findings, however, it was recognized as a chondroblastoma with aneurysmal bone cyst-like change. Good clinical results was obtained by the subtotal resection of the metacarpal bone with a columnar-shaped iliac bone graft.  (+info)

Coexisting chondroblastoma and osteochondroma: a case report. (6/41)

The coexistence of two different types of benign cartilaginous tumours of bone in the same patient has not been reported in literature. We report a case in which a sixteen-year-old male had a benign chondroblastoma of the proximal left humerus and an osteochondroma of the distal left femur. Both originated at the same time and had a progressive increase in size with growth.  (+info)

Chondroblastoma of the temporal base with high mitotic activity. (7/41)

A 24-year-old man presented with a rare chondroblastoma of the temporal base manifesting as local pain accompanied by difficulty in opening the mouth. Gross total removal was achieved at initial surgery, but the tumor demonstrated rapid and destructive regrowth from a very small residual volume without definite histological malignant transformation. Growth activity estimated by MIB-1 staining increased spontaneously from 2.5% at the initial operation to 18.7% at recurrence. Further extensive radical tumor removal by surgeons from multiple disciplines was performed. The patient has been free of recurrence for 3 years without radiotherapy. Chondroblastoma of the temporal bone is widely accepted as a benign tumor and regrowth after gross total removal is very rare. However, some cases of chondroblastoma have potentially high mitotic activity.  (+info)

Skull base chondroblastoma: a case report. (8/41)

Chondroblastoma is a rare tumor of the skull. Temporal bone is the commonest site of involvement in the skull. We present a thirty one year old man who presented with painless swelling over the left temporal bone, which was near totally excised after preoperative embolization. Management of this unusual tumor and its complications are discussed.  (+info)

ETHMOID-SPHENO-PETRO-CLIVAL CHONDROBLASTOMA AND ASOCIATED EPIDURAL ABSCES: CASE REPORT / ETMOIDNO-SFENO-PETRO-KLIVALNI...ETHMOID-SPHENO-PETRO-CLIVAL CHONDROBLASTOMA AND ASOCIATED EPIDURAL ABSCES: CASE REPORT / ETMOIDNO-SFENO-PETRO-KLIVALNI...
cellular. + 381 64 1924274. Abstract. Chondroblastoma is a rare, usually benign, tumour and represent 1% of primary bone tumours. Skull base chondroblastomas are extremely rare, most frequently located in the squamous part of the temporal bone, as reviewed in the literature. The authors report the first case of chondroblastoma ethmoid-spheno-petro-clival associated with epidural abcces that was treated through curretage of the lesion, and drainage of the abccess and antibiotic treatment. The transmaxillar approach is performed: Lefort one and sagittal maxillar osteotomy. Result of intervention was exelent and no complications trancurred. Key words. spheno-petro-clival chondroblastoma, transfacial approach, curettage. References. ...
Chondroblastoma of the patella treated with curettage and bone grafting - International Journal of Conference ProceedingsChondroblastoma of the patella treated with curettage and bone grafting - International Journal of Conference Proceedings
Chondroblastoma is a rare tumor, representing only 1-3% of all primary bone tumors, with local pain and swelling lasting for several months as the most important symptoms. It is usually seen as a lytic lesion involving the epiphysis with a thin border of sclerosis and central punctuate calcification in half of the cases in radiographs. It usually causes expansion or enlargement in the affected site. Primary patella lesions are categorized into benign and malignant tumors and metabolic disorders. Giant cell tumor is the most likely differential diagnoses with tumors of the patella. Patella is a relative uncommon site for chondroblastoma.Most of cases of chondroblastoma in patella reported in literature are treated with patellectomy.We treated a large chondroblastic lesion in patella of an 22 year old male with curettage, burring and bone graft and the result was satisfactory after 8 months postoperation,with complete consolidation of new bone on radiographs, absence of pain and full range of knee ...
NewYork-Presbyterian Queens - ChondroblastomaNewYork-Presbyterian Queens - Chondroblastoma
Sometimes called Codmans tumor, a chondroblastoma is a rare type of benign (noncancerous) bone tumor that originates from cartilage. Cartilage is the specialized, gristly connective tissue and the tissue from which most bones develop. Cartilage plays an important role in the growth process. There are many different types of cartilage that are present throughout the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee.. Chondroblastoma is a rare type of bone tumor that can affect people of all ages. It is, however, most common in children and young adults. This type of tumor is also more common in males than females.. ...
NewYork-Presbyterian Queens - ChondroblastomaNewYork-Presbyterian Queens - Chondroblastoma
Sometimes called Codmans tumor, a chondroblastoma is a rare type of benign (noncancerous) bone tumor that originates from cartilage. Cartilage is the specialized, gristly connective tissue and the tissue from which most bones develop. Cartilage plays an important role in the growth process. There are many different types of cartilage that are present throughout the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee.. Chondroblastoma is a rare type of bone tumor that can affect people of all ages. It is, however, most common in children and young adults. This type of tumor is also more common in males than females.. ...
Chondroblastoma - Health Encyclopedia - University of Rochester Medical CenterChondroblastoma - Health Encyclopedia - University of Rochester Medical Center
A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly connective tissue from which most bones develop. It plays an important role in the growth process. There are many different types of cartilage in the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. It is also called Codmans tumor. Chondroblastoma can affect people of all ages. But, its most common in children and young adults. Its also more common in males than females. ...
a Case of a Benign Chondroblastoma of Bone with a Rare Localization]. - Semantic Scholara Case of a Benign Chondroblastoma of Bone with a Rare Localization]. - Semantic Scholar
Semantic Scholar extracted view of [a Case of a Benign Chondroblastoma of Bone with a Rare Localization]. by K CHOKANOV et al.
Diagnosis of benign chondroblastoma: Costs for treatment #275514 in Germany | BookingHealthDiagnosis of benign chondroblastoma: Costs for treatment #275514 in Germany | BookingHealth
Diagnosis of benign chondroblastoma (costs for program #275514) ✔ Charite University Hospital Berlin ✔ Department of Musculoskeletal Surgery ✔ BookingHealth.com
Diagnosis of benign chondroblastoma: Costs for treatment #219337 in Germany | BookingHealthDiagnosis of benign chondroblastoma: Costs for treatment #219337 in Germany | BookingHealth
Diagnosis of benign chondroblastoma (costs for program #219337) ✔ Academic Hospital Cologne-Holweide ✔ Department of Internal Medicine and Gastroenterology ✔ BookingHealth.com
Proximal humerus chondroblastoma with a secondary aneurysmal bone cystProximal humerus chondroblastoma with a secondary aneurysmal bone cyst
Discussion. Chondroblastomas are rare representing less than 1% of all benign bone tumours1-16 but one author did have the incidence at 5%, possibly only including paediatric bone tumours.17 They arise in the epiphyseal areas of long bones as well as in the apophyses.2-5,7,9-21 Some then extend into the metaphysis.2,3,13,21,22 They occur in the second decade -95% of cases between 5 and 25 years of age.2,6,8,9,11,12,15,21 They appear in males with a ratio of 2-3:1.1,4-11,15-18. They occur mostly in the proximal tibia,7 proximal humerus and proximal femur13,15 as well as in flat bones (34%).3 Seventy-two per cent are found in the lower extremity - 50% around the knee9,19 and 33% in the femur.4 Twenty per cent are found in the humerus9 - 90% of which are in the proximal humerus.4,7 Ten per cent are also found in the small bones of the hands and feet.19 It is the most common tumour of the patella.19 Some say the most frequent site is the proximal humerus.6,11 Some also describe the upper end of the ...
Orthopedics Center - Nebraska MedicineOrthopedics Center - Nebraska Medicine
A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly connective tissue from which most bones develop. It plays an important role in the growth process. There are many different types of cartilage in the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. It is also called Codmans tumor....more ...
Orthopedics CenterOrthopedics Center
A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly connective tissue from which most bones develop. It plays an important role in the growth process. There are many different types of cartilage in the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. It is also called Codmans tumor....more ...
Orthopedics CenterOrthopedics Center
A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly connective tissue from which most bones develop. It plays an important role in the growth process. There are many different types of cartilage in the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. It is also called Codmans tumor....more ...
An aggressive chondroblastoma of the knee treated with resection arthrodesis and limb lengthening using the Ilizarov techniqueAn aggressive chondroblastoma of the knee treated with resection arthrodesis and limb lengthening using the Ilizarov technique
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Browse by People - WestminsterResearchBrowse by People - WestminsterResearch
Behjati Sam, , Tarpey Patrick Campbell Peter, J., Presneau, Nadège, Pillay Nischalan, , Van Loo Peter Hassan A Bassim, , Wedge David C., , Cooke, S.L., Gundem, G., Davies, H., Nik-Zainal, S., Martin, S., McLaren, S., Goody, V., Robinson, B., Butler, A., Teague, J.W., Halai, D., Khatri, B., Myklebost, O., Baumhoer Daniel, , Jundt Gernot, , Hamoudi Rifat Wedge David, C., Tirabosco, R., Amary, M.F., Futreal, P.A., Stratton, M.R., Campbell Peter J., , Flanagan, A.M., Scheipl Susanne, and Goodie Victoria, (2013) Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone. Nature Genetics, 45 (12). pp. 1479-1482 ...
Induction of the Sry-related factor SOX6 contributes to bone morphogenetic protein-2-induced chondroblastic differentiation of...Induction of the Sry-related factor SOX6 contributes to bone morphogenetic protein-2-induced chondroblastic differentiation of...
TY - JOUR. T1 - Induction of the Sry-related factor SOX6 contributes to bone morphogenetic protein-2-induced chondroblastic differentiation of C3H10T1/2 cells. AU - Fernández-Lloris, R.. AU - Viñals, F.. AU - Harley, V.. AU - Ventura, Flaminia. PY - 2003/7/1. Y1 - 2003/7/1. N2 - Chondrogenesis leads to the formation of mature cartilage and generates initial skeletal elements that serve as templates for endochondral bone formation. Bone morphogenetic proteins (BMPs) are involved in several developmental and organogenetic processes and have been identified as key regulators in chondrogenesis. In the present study we sought to determine the transcriptional mechanisms contributing to the induction of chondrogenic markers by BMP-2. Time-course studies with BMP-2-stimulated C3H10T1/2 cells showed a dose-dependent appearance of Alcian-blue-positive material and up-regulated expression of type-II collagen mRNA. This last effect required new protein synthesis because addition of cycloheximide ...
Histone 3.3 Mutations in Giant Cell Tumor and Giant Cell-Rich Sarcomas of Bone.<...Histone 3.3 Mutations in Giant Cell Tumor and Giant Cell-Rich Sarcomas of Bone.<...
TY - JOUR. T1 - Histone 3.3 Mutations in Giant Cell Tumor and Giant Cell-Rich Sarcomas of Bone.. AU - Righi, Alberto. AU - Mancini, Irene. AU - Gambarotti, Marco. AU - Picci, Piero. AU - Gamberi, Gabriella. AU - Marraccini, Cristina. AU - Tos, Angelo Paolo Dei. AU - Simi, Lisa. AU - Pinzani, Pamela. AU - Franchi, Alessandro. PY - 2017/9. Y1 - 2017/9. N2 - Mutually exclusive histone 3.3 gene mutations have been recognized in chondroblastoma and giant cell tumor of bone (GCTB), which may be useful for differential diagnostic purposes in morphologically ambiguous cases. While over 90% of GCTB presents histone 3.3 variants exclusively in the H3F3A gene, chondroblastoma is mutated mainly in H3F3B. In this study we examined a series of giant cell rich primary bone tumors, aiming to evaluate the possible diagnostic role of histone 3.3 mutations in the differential diagnosis between GCTB and giant cell rich sarcomas. Sixteen cases of non-metastatic GCTB, 9 GCTB with lung metastases, and 35 giant ...
Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six...Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six...
Histone 3.3 (H3.3) hotspot mutations in bone tumors occur in the vast majority of giant cell tumors of bone (GCTBs; 96%), chondroblastomas (95%) and in a few cases of osteosarcomas. However, clinical presentation, histopathological features, and additional molecular characteristics of H3.3 mutant osteosarcomas are largely unknown. In this multicentre, retrospective study, a total of 106 conventional high-grade osteosarcomas, across all age groups were re-examined for hotspot mutations in the H3.3 coding genes H3F3A and H3F3B. H3.3 mutant osteosarcomas were re-evaluated in a multidisciplinary manner and analyzed for genome-wide DNA-methylation patterns and DNA copy number aberrations alongside H3.3 wild-type osteosarcomas and H3F3A G34W/L mutant GCTBs. Six osteosarcomas (6/106) carried H3F3A hotspot mutations. No mutations were found in H3F3B. All patients with H3F3A mutant osteosarcoma were older than 30 years with a median age of 65 years. Copy number aberrations that are commonly encountered in high
Recurrence of chondromyxoid fibroma of great toe<...Recurrence of chondromyxoid fibroma of great toe<...
TY - JOUR. T1 - Recurrence of chondromyxoid fibroma of great toe. AU - Mallya, P. Sharan. AU - Sujir, Premjit. PY - 2018/7/1. Y1 - 2018/7/1. N2 - Chondromyxoid fibroma (CMF) is a benign cartilaginous tumour which involves mainly the long bones and proximal tibia being common. CMF of foot and phalanx is very rare. Various treatment options are available for this tumour and recurrences have been reported following surgery. 24 year old male was treated with curettage and bone grafting for chondromyxoid fibroma of great toe 8 years back. 6 years later, he presented with local recurrence of tumour with extensive soft tissue involvement. He was treated with amputation of great toe. After two years follow up, patient was symptom free.. AB - Chondromyxoid fibroma (CMF) is a benign cartilaginous tumour which involves mainly the long bones and proximal tibia being common. CMF of foot and phalanx is very rare. Various treatment options are available for this tumour and recurrences have been reported ...
Case No. 2: Giant Cell Tumor - Bone Tumor Radiology DefinitionCase No. 2: Giant Cell Tumor - Bone Tumor Radiology Definition
Giant cell tumors (GCTs) are common benign bone tumors also known as osteoclastomas. They arise from metaphysis and extends into the epiphysis of the long bones. The lesions usually shows narrow zone of transition, thin cortex, no sclerosis. Differentials include chondroblastoma, aneurysmal bone cyst and enchondroma.. ...
Bone: Chondromyxoid fibromaBone: Chondromyxoid fibroma
... , Authors: Salvatore Romeo, Pancras CW Hogendoorn. Published in: Atlas Genet Cytogenet Oncol Haematol.
Expression of P-glycoprotein in high grade osteosarcomas with special emphasis on chondroblastic subtype<...Expression of P-glycoprotein in high grade osteosarcomas with special emphasis on chondroblastic subtype<...
TY - JOUR. T1 - Expression of P-glycoprotein in high grade osteosarcomas with special emphasis on chondroblastic subtype. AU - Radig, K.. AU - Hackel, C.. AU - Herting, J.. AU - Oda, Y.. AU - Mittler, U.. AU - Neumann, W.. AU - Roessner, A.. PY - 1997/3/15. Y1 - 1997/3/15. N2 - The development of chemoresistance is one of the major clinical problems in the therapy of malignant bone tumors in childhood. The expression of membrane-bound P-glycoprotein turned out to be an essential factor in the evidence of resistant tumor cells. To investigate the significance of multidrug resistance in the prognosis of highly malignant osteosarcomas, the immunohistologic expression of P-glycoprotein was investigated in the tumor tissue of 52 patients under special consideration of the histologic subtype. The data were compared with the histologic regression grade in the resection specimen and correlated with clinical data. Formalin-fixed, paraffin-embedded tissue and, additionally, fresh frozen material taken ...
Global Pigmented Villonodular Synovitis Drug Market Data Analysis 2019-2025 : Bristol-Myers Squibb Co, F. Hoffmann-La Roche Ltd...Global Pigmented Villonodular Synovitis Drug Market Data Analysis 2019-2025 : Bristol-Myers Squibb Co, F. Hoffmann-La Roche Ltd...
Pigmented Villonodular Synovitis Drug market studies the competitive landscape read of the business. The Pigmented Villonodular Synovitis Drug report conjointly includes development plans and policies at the side of producing processes. the foremost regions concerned in Pigmented Villonodular Synovitis Drug Market square measure (United States, EU, China, and Japan).. Get Sample Copy of Report Here: @ www.e-marketresearch.com/request-sample-23250.html. Producers Analysis and prime Sellers of world Pigmented Villonodular Synovitis Drug Market 2019: Bristol-Myers Squibb Co, F. Hoffmann-La Roche Ltd, Novartis AG, Plexxikon Inc. The Pigmented Villonodular Synovitis Drug report will the thorough study of the key business players to grasp their business methods, annual revenue, company profile and their contribution to the world Pigmented Villonodular Synovitis Drug market share. numerous factors of the Pigmented Villonodular Synovitis Drug business just like the offer chain state of affairs, business ...
Expression of metalloproteinases in pigmented villonodular synovitis by Jama M. Darling, Laurie H. Glimcher et al."Expression of metalloproteinases in pigmented villonodular synovitis" by Jama M. Darling, Laurie H. Glimcher et al.
Pigmented villonodular synovitis (PVNS) is an idiopathic proliferative synovial process composed of two predominant cell types: mononuclear histiocytic cells and giant cells. This lesion can be locally invasive and can result in bone cyst formation and late cartilage and bone loss. Because metalloproteinases have been implicated in the joint destruction occurring in inflammatory arthritis and in the ability of certain tumors to invade adjacent tissues, their presence in PVNS was determined. Synovial tissue samples were collected at surgical synovectomy from the knees of 10 patients with a prior histological diagnosis of PVNS. Pigmented villonodular synovitis synovium was examined for the presence of the metalloproteinases collagenase and stromelysin. Messenger RNA (mRNA) for collagenase and stromelysin was present in all patient samples, although in varying amounts. In situ hybridization studies on synovial tissue sections identified synovial lining cells as the predominant cells expressing these
Pigmented villonodular synovitis - WikipediaPigmented villonodular synovitis - Wikipedia
Pigmented villonodular synovitis (PVNS) is a joint disease characterized by inflammation and overgrowth of the joint lining. It usually affects the hip or knee. It can also occur in the shoulder, ankle, elbow, hand or foot. In PVNS the lining of the joint, called the synovium, becomes swollen and grows. This growth harms the bone next to the joint. The lining also makes extra fluid that can cause swelling and make movement painful. PVNS is idiopathic, it doesnt seem to run in families or be caused by certain jobs or activities. Surgery can help but, even with treatment, PVNS comes back about half the time. If the pain remains then radiation therapy may help. In the worst cases the joint must be replaced. In general, pigmented villonodular synovitis often manifests initially as sudden onset, unexplained joint swelling and pain; the joint swelling is disproportionate to the amount of pain the patient feels at first. Decreased motion and increased pain occur as the disorder progresses as well as ...
Plexxikon Announces Promising Preliminary PLX3397 Phase 1 Extension Data in Patients with Pigmented Villonodular Synovitis ...Plexxikon Announces Promising Preliminary PLX3397 Phase 1 Extension Data in Patients with Pigmented Villonodular Synovitis ...
Plexxikon, a member of the Daiichi Sankyo Group, announced today promising, proof-of-concept Phase 1 extension clinical data with PLX3397 in pigmented villonodular synovitis (PVNS), a type of rare, often locally aggressive, musculoskeletal neoplasm that arises from the soft tissues of joints and tendons. Interim data from this ongoing trial show that all evaluable patients treated with PLX3397 achieved either partial responses or stable disease. PLX3397 is a novel, oral small molecule that potently and selectively inhibits CSF1R, KIT and oncogenic FLT3 kinases, which play important roles in cancer. CSF1R, in particular, has been shown to be a primary driver in PVNS. These data are being released today as part of the American Society of Clinical Oncology (ASCO) 50th Annual Meeting Press Program. More detailed data will be presented at the ASCO 50th Annual Meeting, being held May 31-June 3 in Chicago.. The data come from an extension cohort of a multicenter Phase 1 clinical study in solid tumors ...
Pigmented villonodular synovitis of the hip in systemic lupus erythematosus: a case report | springermedizin.dePigmented villonodular synovitis of the hip in systemic lupus erythematosus: a case report | springermedizin.de
Pigmented villonodular synovitis (PVNS) is a rare monoarticular proliferative synovial disorder of unknown etiology mostly affecting the knee, foot
Alternative treatments for pigmented villonodular synovitis - Doctor answersAlternative treatments for pigmented villonodular synovitis - Doctor answers
HealthTap: Doctor answers on Symptoms, Diagnosis, Treatment, and More: Dr. Krauser on alternative treatments for pigmented villonodular synovitis: Start with oral antiinflammatory medications, such as aleve (naproxen) or advil. A steroid taper would be the next step, or an injection into the hip with a steroid medication could be performed.
My Misery : I Have Pigmented Villonodular Synovitis Story & ExperienceMy Misery : I Have Pigmented Villonodular Synovitis Story & Experience
My Misery : A true, personal story from the experience, I Have Pigmented Villonodular Synovitis. I am 26 years old and have been diagnosed with PVNS in my left hip for the last 5 years. I remember the symptoms started back when I was 14 years old. I had my first synovectomy in 2005 at the age of...
Pvns ? You Couldnt Make This Disease Up. : I Have Pigmented Villonodular Synovitis Story & ExperiencePvns ? You Couldn't Make This Disease Up. : I Have Pigmented Villonodular Synovitis Story & Experience
Pvns ? You Couldnt Make This Disease Up. : A true, personal story from the experience, I Have Pigmented Villonodular Synovitis. Hi Simon here, 45, diagnosed 4 weeks ago, had an arthroscopic synovectomy last Monday.. Went well, up and walking. I normally post on the facebook group pvns is pants.. I guess Im looking to find a...
AbstractAbstract
title:Radiotherapy for Pigmented Villonodular Synovitis: A Case Report. Author:Navin Nayan, Vikas K Jagtap. Keywords:Radiotherapy, PVNS (Pigmented Villonodular Synovitis), Surgery. Type:Case report. Abstract:This is a case report of a 13 year old boy who has been operated for Pigmented Villonodular Synovitis (PVNS) and treated with adjuvant post-operative radiotherapy for incomplete surgical resection. This report mainly highlights the role of radiotherapy in managing this rare benign condition with emphasis on improving local control rates with functional joint preservation and avoiding repeated surgeries.. ...
Pigmented Villonodular Synovitis PVNS Symptoms &TreatmentPigmented Villonodular Synovitis PVNS Symptoms &Treatment
Pignmented villonodular synovitis or PVNS is a benign tumor in the joint. Learn about the symptoms PVNS and treatment options for PVNS.
Chondromyxoid fibromaChondromyxoid fibroma
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What is aneurysmal bone cyst? | Nicklaus Childrens HospitalWhat is aneurysmal bone cyst? | Nicklaus Children's Hospital
When a blood-filled growth occurs in the bones of the arms, legs, skull, trunk or spine, then it might be an aneurysmal bone cyst.
Villonodular synovitisVillonodular synovitis
Build: Wed Jun 21 18:33:50 EDT 2017 (commit: 4a3b2dc). National Center for Advancing Translational Sciences (NCATS), 6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-435-0888. ...
DI-fusion Sacral aneurysmal bone cyst:CT and MR imaging : diagnosis by...DI-fusion Sacral aneurysmal bone cyst:CT and MR imaging : diagnosis by...
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
Frequent expression of fibroblast growth factor-23 (FGF23) mRNA in aneurysmal bone cysts and chondromyxoid fibromas.</strong>...Frequent expression of fibroblast growth factor-23 (FGF23) mRNA in aneurysmal bone cysts and chondromyxoid fibromas.</strong>...
TY - JOUR. T1 - Frequent expression of fibroblast growth factor-23 (FGF23) mRNA in aneurysmal bone cysts and chondromyxoid fibromas. AU - Graham, Rondell. AU - Krishnamurthy, Smita. AU - Oliveira, Andre. AU - Inwards, Carrie. AU - Folpe, Andrew L.. PY - 2012/10/1. Y1 - 2012/10/1. N2 - Osteomalacia has multiple aetiologies including the least common, tumour-induced osteomalacia (TIO). Recently, most cases of TIO have been confirmed to be due to phosphaturic mesenchymal tumour of mixed connective tissue type (PMTMCT). Most cases of TIO are the result of production of the fibroblast growth factor-23 (FGF-23) by the tumour. The authors recently showed reverse transcriptase PCR (RT-PCR) for FGF-23 to be valuable in the diagnosis of PMTMCT. However, the authors also noted FGF-23 expression in some cases of aneurysmal bone cyst (ABC) and chondromyxoid fibroma (CMF). For the present study, the authors studied FGF-23 expression by RT-PCR in 19 cases of ABC and eight cases of CMF, all with typical ...
AM 760 KFMB - Talk Radio Station - San Diego, CA - Pigmented Villonodular Synovitis Drug Capacity, Production, ReveAM 760 KFMB - Talk Radio Station - San Diego, CA - Pigmented Villonodular Synovitis Drug Capacity, Production, Reve
The global Pigmented Villonodular Synovitis Drug market is valued at USD XX million in 2017 and is expected to reach USD XX million by the end of 2025, growing at a CAGR of XX% between 2018...
Aneurysmal bone cyst involving the lunate.</strong>...Aneurysmal bone cyst involving the lunate.</strong>...
TY - JOUR. T1 - Aneurysmal bone cyst involving the lunate. AU - Mankin, K. P.. AU - Bischoff, R. J.. AU - Gelberman, R. H.. AU - Rosenberg, Andrew. PY - 1995/1/1. Y1 - 1995/1/1. N2 - Aneurysmal bone cysts are rare lesions which even more rarely involve the bones of the hand. We report a case of a cyst involving the lunate which was initially mistaken for interosseous ganglion. Due to delay in diagnosis, marked destruction of the lunate occurred, necessitating excision and scapho-capitate arthrodesis. Although rare, aneurysmal bone cysts should be included in the differential diagnosis and ruled out prior to embarking on a course of treatment.. AB - Aneurysmal bone cysts are rare lesions which even more rarely involve the bones of the hand. We report a case of a cyst involving the lunate which was initially mistaken for interosseous ganglion. Due to delay in diagnosis, marked destruction of the lunate occurred, necessitating excision and scapho-capitate arthrodesis. Although rare, aneurysmal bone ...
Cureus | Chondromyxoid Fibroma of Distal Phalanx of the Great Toe: A Rare Clinical EntityCureus | Chondromyxoid Fibroma of Distal Phalanx of the Great Toe: A Rare Clinical Entity
Chondromyxoid fibroma is a rare benign tumor of cartilaginous origin with myxoid and fibrous components. It accounts for approximately 1% of bone tumors. Metaphysis of long bones is the most common location of this tumor. However, there a few case reports of this tumor arising from epiphysis of short tubular bones of the hand and feet. An 11-year-old girl presented to our OPD with complaints of pain and a gradually progressive swelling of the right great toe. On examination, the swelling was diffuse with no signs of inflammation. X-ray examination revealed a well-defined, longitudinally oval lytic lesion in the right distal phalanx of great toe, involving the growth plate and, eroding the medial cortex. Computed tomography (CT) scan did not show any evidence of calcification, septations or involvement of soft tissue. Open biopsy and curettage was done and the specimen was sent for histopathological examination. Histopathological examination (HPE) showed a lobular pattern consisting of myxomatous
MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCTTS) - Full Text...MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCTTS) - Full Text...
In the single dose Part A of the study, patients receive 1 dose of of 10 mg/kg MCS110 administered i.v. on Day 1.. In the multiple dose Part B patients receive up to 6 doses of 10 mg/kg MCS110 administered i.v. once every 4 weeks starting at Day 1, or at Day 29 if the first dose received was placebo.. In the multiple dose Part C patients receive up to 6 doses of 3 mg/kg or 5 mg/kg or 10 mg/kg MCS110 administered i.v. once every 4 weeks starting at Day 1. ...
Aneurysmal bone cyst, X-ray - Stock Image C003/6331 - Science Photo LibraryAneurysmal bone cyst, X-ray - Stock Image C003/6331 - Science Photo Library
Aneurysmal bone cyst. X-ray showing an aneurysmal bone cyst (dark patch, upper left) on the lower fibula (calf bone) of a patients leg. This cyst is a lesion on the bone which has a thin wall containing blood filled cyst cavities. A giant cell tumour is the most common cause, although it may be due to an injury of the bone. - Stock Image C003/6331
Diagnostic Radiology/Musculoskeletal Imaging/Joint Disorders/Pigmented villonodular synovitis - Wikibooks, open books for an...Diagnostic Radiology/Musculoskeletal Imaging/Joint Disorders/Pigmented villonodular synovitis - Wikibooks, open books for an...
In the hip, bone lesions typically develop at the junction of the femoral head and neck, and acetabulum. Additionally, erosions are more commonly seen than in the knee due to the tight capsule of the hip joint.. ...
Lirias: Pigmented villonodular synovitis in the knee of a 5-year-old boyLirias: Pigmented villonodular synovitis in the knee of a 5-year-old boy
Purpose of the study Case report of a five-year-old boy presenting with a painless swelling of the left knee with decreased range of motion ...
Pigmented Villonodular Synovitis Drug Capacity, Production, Revenue (Value) by Region (2013-2018): Global Market Research -...Pigmented Villonodular Synovitis Drug Capacity, Production, Revenue (Value) by Region (2013-2018): Global Market Research -...
Jan 16, 2018. PARIS - The Latest on Airbus (all times local): 9:50 a.m. Airbus says it sold more than 1,100 planes last year, outselling rival Boeing thanks to a raft of end-of-year deals and a growing global economy and travel demand. The European planemaker reported Monday that it delivered 718 planes in 2017, fewer than Boeings 763 but a record for Airbus. Outgoing CEO Fabrice Bregier said Airbus will speed up production in the coming year, notably of its long-delayed widebody A350, and hopes to out-deliver Boeing by 2020. Bregier acknowledged "challenges" ahead but called them "manageable." Airbus is facing multiple corruption... ...
Secondary jaw aneurysmal bone cyst (JABC)--a possible misnomer? A review of literature on secondary JABCs, their pathogenesis...Secondary jaw aneurysmal bone cyst (JABC)--a possible misnomer? A review of literature on secondary JABCs, their pathogenesis...
Aneurysmal bone cysts are rare pseudocysts, commonly seen in long bones and vertebral column. Although a well described and reported lesion, many misconceptions still prevail regarding their etiopathogenesis. Many of the reported cases of jaw aneurys
problem Archives - familydoctor.orgproblem Archives - familydoctor.org
Learn about the symptoms, diagnosis and treatment of pigmented villonodular synovitis (PVNS), a condition that can cause joint pain and… ...
Kims Blank Canvas: knee updateKim's Blank Canvas: knee update
We went to the Orthopedic Surgeon today and he has a probable prognosis according to the MRI results. He is pretty certain that it is Pigmented Villonodular Synovitis (PVNS). When looking at the MRI, he found swollen tissue around her knee joint, thus producing fluid. This swollen tissue and fluid is what is hindering her walking. The Doctor is planning to get a tissue sample and draw some of the fluid out to test and be 100% certain that its PVNS ...
2020 ICD-10-CM Diagnosis Code M12.239: Villonodular synovitis (pigmented), unspecified wrist2020 ICD-10-CM Diagnosis Code M12.239: Villonodular synovitis (pigmented), unspecified wrist
Free, official coding info for 2020 ICD-10-CM M12.239 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
What is the recovery time for an aneurismal bone cyst? - Answered by top doctors on HealthTapWhat is the recovery time for an aneurismal bone cyst? - Answered by top doctors on HealthTap
Dr. Michalski responded: ABC. Aneurysmal bone cysts treated surgically heal in approximately 6 weeks--depending on the personality and location and size of the cyst. If it is fractured/displaced it may take somewhat longer.
Aneurysmal Bone Cyst In Metacarpal of a Child | Journal of Orthopaedic Case ReportsAneurysmal Bone Cyst In Metacarpal of a Child | Journal of Orthopaedic Case Reports
Introduction: Aneurysmal bone cyst is a rare, rapidly growing, and destructive benign bone tumor that rarely involves the bones of the hand. Various treatment options for aneurysmal bone cyst have been reported in the literature, but controversy exists regarding optimal treatment. Case Report: A six year old boy presented with a history of pain and local swelling over his third metacarpal of five months duration. Physical and radiographic examination of the hand was consistent with aneurysmal bone cyst. After biopsy, pathologic examination confirmed the diagnosis of aneurysmal bone cyst. En- block resection of the tumor and autologous fibular strut graft fixation with Kirschner wires was performed. The hand was immobilized in a short arm cast for three weeks; after the patient received three weeks of physiotherapy, the kirschner wires were removed six weeks postoperatively. Excellent clinical and functional results were obtained with no recurrence after two years of follow-up with en-block resection
Aneurysmal bone cyst in central ossifying fibroma: lesion in a lesion, mandible | International Journal of Current ResearchAneurysmal bone cyst in central ossifying fibroma: "lesion in a lesion", mandible | International Journal of Current Research
Aneurysmal bone cysts (ABCs), a rare distinct pathologic entity, is an intraosseous, osteolytic lesion seen as locally destructive, rapidly expansile which has been reported to affect mainly the metaphyseal region of long bones and vertebrae. Aneurysmal bone cysts secondary to ossifying fibroma remains a relatively uncommon finding in the facial bones, and it is extremely rare with only very few cases reported in the mandible. This case report reveals one such, in a 42 year old lady, who presented with a solitary swelling of the right mandible, with obliterated vestibular depth, which showed Central Ossifying Fibroma as a pre-existing lesion, transforming into Aneurysmal Bone Cyst. Such rare entities are usually misdiagnosed and this gradually results in inappropriate treatment planning and poor prognosis.. ...
Aneurysmal bone cyst variant translocations upregulate USP6 transcription by promoter swapping with the ZNF9, COL1A1, TRAP150,...Aneurysmal bone cyst variant translocations upregulate USP6 transcription by promoter swapping with the ZNF9, COL1A1, TRAP150,...
TY - JOUR. T1 - Aneurysmal bone cyst variant translocations upregulate USP6 transcription by promoter swapping with the ZNF9, COL1A1, TRAP150, and OMD genes. AU - Oliveira, Andre M.. AU - Perez-Atayde, Antonio R.. AU - Dal Cin, Paola. AU - Gebhardt, Mark C.. AU - Chen, Chang Jie. AU - Neff, James R.. AU - Demetri, George D.. AU - Rosenberg, Andrew E.. AU - Bridge, Julia A.. AU - Fletcher, Jonathan A.. PY - 2005/5/12. Y1 - 2005/5/12. N2 - Aneurysmal bone cysts (ABC) are locally aggressive bone tumors that often feature chromosome 17p13 rearrangements. One of the ABC 17p13 rearrangements - t(16;17)(q22;p13) - was recently shown to create a CDH11-USP6 fusion in which the USP6/TRE17 oncogene is overexpressed through juxtaposition with the CDH11 promoter. Herein, we characterize four different ABC translocations involving 17p13, and we show that each is associated with a novel USP6 fusion oncogene. Specifically, we demonstrate that t(1;17), t(3;17), t(9;17), and t(17;17) result in USP6 fusions with ...
Chondromyxoid fibroma of the femur: a case report with intra-cortical location.Chondromyxoid fibroma of the femur: a case report with intra-cortical location.
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Surgical treatment of active or aggressive aneurysmal bone cysts in children | AVESİSSurgical treatment of active or aggressive aneurysmal bone cysts in children | AVESİS
The aim of this study was to evaluate functional and radiological results, tumor control, and complications of the surgical treatment of aneurysmal bone cysts (ABCs) in children by extended curettage using a mechanical burr and cauterization, grafting, and internal fixation in specific locations. Sixty-four children [38 males, 26 females, median age=10 years (range, 5-18 years)] with active or aggressive ABCs of long and flat bones were subjected to a median follow-up of 66 months (range, 28-130 months) following surgical treatment. The pathological fracture rate was 72%. Surgical procedures included intralesional extended curettage (92%) or en-bloc resection (8%). Internal fixation was required in 53%. The pathological fractures healed successfully in 8-12 weeks. The median Musculoskeletal Tumor Society (MSTS) score at the last follow-up was 95% (range, 55-100%). Treatment failure (partial healing/recurrence) and complication rates following extended curettage were 7 and 5.2%, respectively. ...
antigens and extracellular matrices in the control of cell growth | High-Throughput Screen for the Chemical Inhibitorsantigens and extracellular matrices in the control of cell growth | High-Throughput Screen for the Chemical Inhibitors
17-DMAG HCl (Alvespimycin) chondroblastic (36%) and the most frequent major tumor sites had been the 17-DMAG HCl (Alvespimycin) femur (64%) tibia (21%) humerus (7%) and pelvis (7%). All individuals had been treated with high-dose methotrexate doxorubicin and cisplatin with one affected person receiving extra ifosfamide and two individuals receiving extra ifosfamide and etoposide. Extra patient characteristics is seen in Extra file 2: Desk S1. GD2 manifestation The amount of variability between three 3rd party observers was evaluated to be nonsignificant utilizing a two-factor ANOVA without alternative (p?=?0.24) as well as the intraclass relationship coefficient was found to become 0.72 suggesting a good to good Rabbit polyclonal to SHP-2.SHP-2 a SH2-containing a ubiquitously expressed tyrosine-specific protein phosphatase.It participates in signaling events downstream of receptors for growth factors, cytokines, hormones, antigens and extracellular matrices in the control of cell growth,. degree ...
Emile RiachiEmile Riachi
EpiphysisEpiphysis
H3F3B (gene)H3F3B (gene)
H3F3AH3F3A
Giant-cell tumor of boneGiant-cell tumor of bone
Aneurysmal bone cystAneurysmal bone cyst
BlastomaBlastoma
List of diseases (C)List of diseases (C)
List of MeSH codes (C04)List of MeSH codes (C04)
Index of trauma & orthopaedics articlesIndex of trauma & orthopaedics articles
International Classification of Diseases for OncologyInternational Classification of Diseases for Oncology
ChondroblastomaChondroblastoma
Osteoid osteomaOsteoid osteoma
AnatomyDiseasesAnalytical, Diagnostic and Therapeutic Techniques and EquipmentDisciplines and OccupationsHumanitiesInformation ScienceGeographicals
ChondroblastomaCurettageFoot BonesBone Cysts, AneurysmalTemporal BoneBone NeoplasmsFemoral NeoplasmsTarsal BonesSkull NeoplasmsHumerusGiant Cell Tumor of BoneEncyclopedias as TopicShoulder FracturesBone CystsArthrodesisIlizarov TechniqueArchivesBiological Science DisciplinesPeriodicals as TopicPubMedGastroenterologyGermany
Chondroblastoma - Health Encyclopedia - University of Rochester Medical CenterChondroblastoma - Health Encyclopedia - University of Rochester Medical Center
NewYork-Presbyterian Queens - ChondroblastomaNewYork-Presbyterian Queens - Chondroblastoma
Proximal humerus chondroblastoma with a secondary aneurysmal bone cystProximal humerus chondroblastoma with a secondary aneurysmal bone cyst
An aggressive chondroblastoma of the knee treated with resection arthrodesis and limb lengthening using the Ilizarov techniqueAn aggressive chondroblastoma of the knee treated with resection arthrodesis and limb lengthening using the Ilizarov technique
Diagnosis of benign chondroblastoma: Costs for treatment #219337 in Germany | BookingHealthDiagnosis of benign chondroblastoma: Costs for treatment #219337 in Germany | BookingHealth
ETHMOID-SPHENO-PETRO-CLIVAL CHONDROBLASTOMA AND ASOCIATED EPIDURAL ABSCES: CASE REPORT / ETMOIDNO-SFENO-PETRO-KLIVALNI...ETHMOID-SPHENO-PETRO-CLIVAL CHONDROBLASTOMA AND ASOCIATED EPIDURAL ABSCES: CASE REPORT / ETMOIDNO-SFENO-PETRO-KLIVALNI...
a Case of a Benign Chondroblastoma of Bone with a Rare Localization]. - Semantic Scholara Case of a Benign Chondroblastoma of Bone with a Rare Localization]. - Semantic Scholar
Chondroblastoma of the patella treated with curettage and bone grafting - International Journal of Conference ProceedingsChondroblastoma of the patella treated with curettage and bone grafting - International Journal of Conference Proceedings
Browse by People - WestminsterResearchBrowse by People - WestminsterResearch
Orthopedics Center - Nebraska MedicineOrthopedics Center - Nebraska Medicine
Chondroblastoma - WikipediaChondroblastoma - Wikipedia
Chondroblastoma Treatment & Management: Medical Therapy, Surgical Therapy, ComplicationsChondroblastoma Treatment & Management: Medical Therapy, Surgical Therapy, Complications
Chondroblastoma Pathology: Overview, Clinical Features, Radiography and MRIChondroblastoma Pathology: Overview, Clinical Features, Radiography and MRI
Chondroblastoma | Cooper University Health CareChondroblastoma | Cooper University Health Care
Chondroblastoma | Childrens Hospital of PhiladelphiaChondroblastoma | Children's Hospital of Philadelphia
Chondroblastoma of the Knee Treated with Resection and Osteochondral Allograft ReconstructionChondroblastoma of the Knee Treated with Resection and Osteochondral Allograft Reconstruction
A Massive Chondroblastoma in the Proximal Humerus Simulating Malignant Bone TumorsA Massive Chondroblastoma in the Proximal Humerus Simulating Malignant Bone Tumors
Benign chondroblastoma of the occipital bone: case reportBenign chondroblastoma of the occipital bone: case report
Surgical Dislocation of the Hip for the Treatment of a Femoral Head Chondroblastoma | International Congress for Joint...Surgical Dislocation of the Hip for the Treatment of a Femoral Head Chondroblastoma | International Congress for Joint...
Metastatic chondroblastoma with elevated creatine kinase and paraneoplastic neurologic autoimmunity. - Semantic ScholarMetastatic chondroblastoma with elevated creatine kinase and paraneoplastic neurologic autoimmunity. - Semantic Scholar
ChondroblastomaChondroblastoma
Chondroblastoma : Bone Cancer Tumors : Tumors of the boneChondroblastoma : Bone Cancer Tumors : Tumors of the bone
Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases<...Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases<...
ChondroblastomaChondroblastoma
Spot Diagnosis: ChondroblastomaSpot Diagnosis: Chondroblastoma
Reconstruction with double pedicel fibular graft and ankle arthrodesis for aggressive chondroblastoma in the distal tibia |...Reconstruction with double pedicel fibular graft and ankle arthrodesis for aggressive chondroblastoma in the distal tibia |...
conditioncondition
Non-cancerous tumours of the bone - Canadian Cancer SocietyNon-cancerous tumours of the bone - Canadian Cancer Society
Wheeless Textbook of OrthopaedicsWheeless' Textbook of Orthopaedics
Jun 1985 - Volume 67 - Issue 5 : JBJSJun 1985 - Volume 67 - Issue 5 : JBJS
Surgery: Chondroblastoma | Surgical resection. Treatment in Cologne, Germany | BookingHealthSurgery: Chondroblastoma | Surgical resection. Treatment in Cologne, Germany | BookingHealth
Chondroblastoma of Ventral Skull Base: First Report of a CaseChondroblastoma of Ventral Skull Base: First Report of a Case
October 1951 - Volume 33 - Issue 4 : JBJSOctober 1951 - Volume 33 - Issue 4 : JBJS
Chondroblastoma | Genetic and Rare Diseases Information Center (GARD) - an NCATS ProgramChondroblastoma | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program
AnatomyDiseasesAnalytical, Diagnostic and Therapeutic Techniques and EquipmentDisciplines and OccupationsHumanitiesInformation ScienceGeographicals
ChondroblastomaCurettageFoot BonesBone Cysts, AneurysmalTemporal BoneBone NeoplasmsFemoral NeoplasmsTarsal BonesSkull NeoplasmsHumerusGiant Cell Tumor of BoneEncyclopedias as TopicShoulder FracturesBone CystsArthrodesisIlizarov TechniqueArchivesBiological Science DisciplinesPeriodicals as TopicPubMedGastroenterologyGermany
Benign chondroblastomaSymptoms of chondroblastomaTumorKneeFibromaChondromaPatients presenting with chonOsteoblastomaCartilageTumorsFemurAneurysmal bone cystsConsistent with a chondroblastomaDistalLesionsCase of chondroblastomaLocation of chondroblastomaCharacteristics of chondroblastomaFemoralSymptomsLesionSecondary aneurysmal boneBone cystFibulaResectionNeoplasmSurgicalRareTemporalChondroid matrixOssification centersSkullMalesOsteosarcomaRadiologyAggressive
Benign chondroblastoma1
Symptoms of chondroblastoma2
Tumor3
Knee1
  • Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. (rochester.edu)
Fibroma1
Chondroma1
Patients presenting with chon1
  • Approximately 92% of patients presenting with chondroblastoma are younger than 30 years. (wikipedia.org)
Osteoblastoma2
Cartilage4
  • Additionally, rare prevalence of chondroblastoma in intra-membranous ossification suggests a close relationship with growth plate cartilage. (wikipedia.org)
  • In chondroblastoma, growth signaling molecules may be present due to the pre-pubertal signaling network as well as cartilage growth. (wikipedia.org)
  • The work of Aigner et al suggests that chondroblastoma should be reclassified as a bone-forming neoplasm versus a cartilaginous neoplasm due to the presence of osteoid matrix, type I collagen, and absence of true cartilage matrix (collagen II). (wikipedia.org)
  • generally, because the bones at the base of the skull develop from cartilage, they have a greater potential for developing chondroblastoma. (medscape.com)
Tumors5
  • Chondroblastoma is very uncommon, accounting for only 1-2% of all bone tumors. (wikipedia.org)
  • The etiology of chondroblastoma is uncertain, as there is no specific characteristic abnormality or chromosomal breaking point observed, despite cytogenetic abnormalities being highly specific for some tumors. (wikipedia.org)
  • Chondroblastoma was first described by Codman in 1928 as "epiphyseal chondromatous giant cell tumors of the proximal humerus" [ 1 ]. (hindawi.com)
  • A Massive Chondroblastoma in the Proximal Humerus Simulating Malignant Bone Tumors," Case Reports in Orthopedics , vol. 2013, Article ID 673576, 5 pages, 2013. (hindawi.com)
  • Chondroblastoma is a rare neoplasm of the bone constituting approximately 1% of all primary bone tumors. (clinmedjournals.org)
Femur3
Aneurysmal bone cysts2
  • [ 17 ] On these images, the chondroblastoma may mimic aneurysmal bone cysts, which are also expansile and osteolytic. (medscape.com)
  • It is uncertain why chondroblastoma occurs, but it is sometimes found in conjunction with other growths, such aneurysmal bone cysts , which are found in 20-25 percent of all patients with chondroblastoma. (chop.edu)
Consistent with a chondroblastoma1
Distal3
  • Aggressive chondroblastoma of the distal tibia is rare, and below-knee amputation had been the standard surgical procedure. (biomedcentral.com)
  • Double pedicel fibular graft and ankle arthrodesis may be an effective and economical alternative method for aggressive chondroblastoma in the distal tibia. (biomedcentral.com)
  • Aggressive chondroblastoma of the distal tibia is further rare. (biomedcentral.com)
Lesions1
  • RFA for chondroblastoma has been described in several reports, but follow-up has been shorter than for surgical treatment, and caution is recommended for cases in which the lesions are larger than 2.5 cm and when there is no subchondral bone support. (medscape.com)
Case of chondroblastoma2
  • Report of the first case of chondroblastoma involving the sinonasal cavity and ventral skull base, offering a description of the puzzling diagnostic process followed by its management. (clinmedjournals.org)
  • The authors report the first case of chondroblastoma ethmoid-spheno-petro-clival associated with epidural abcces that was treated through curretage of the lesion, and drainage of the abccess and antibiotic treatment. (md-medicaldata.com)
Location of chondroblastoma1
Characteristics of chondroblastoma1
  • We describe the main radiologic and histologic characteristics of chondroblastoma and compare them to those of frequently mistaken differential diagnoses. (clinmedjournals.org)
Femoral4
Symptoms4
Lesion1
  • On radiographic images, chondroblastoma is characterized by a well-defined osteolytic lesion involving an epiphysis or secondary ossification center (see the following image). (medscape.com)
Secondary aneurysmal bone3
Bone cyst2
Fibula1
Resection3
Neoplasm2
  • However, Edel et al found that collagen II, a marker for mature chondrocytes, was expressed in chondroblastoma, supporting the chondroid nature of the neoplasm. (wikipedia.org)
  • The results of Romeo and colleagues favor the view of Edel et al of chondroblastoma being cartilaginous in nature but recognize that any definitive determinations regarding the origin of this neoplasm are not possible because of the plasticity of mesenchymal cells when set into different microenvironments and static approaches used in literature. (wikipedia.org)
Surgical1
Rare5
Temporal4
Chondroid matrix1
  • Presence of extensive surrounding reactive edema within the marrow and soft tissues, sclerotic margin, and presence of chondroid matrix are helpful features distinguishing chondroblastoma from GCT. (thefreedictionary.com)
Ossification centers2
Skull1
Males1
Osteosarcoma1
Radiology1
Aggressive2
Chondroblastoma of the patella treated with curettage and bone grafting - International Journal of Conference Proceedings
Chondroblastoma of the patella treated with curettage and bone grafting - International Journal of Conference Proceedings (jocponline.com)
Chondroblastoma Pathology: Overview, Clinical Features, Radiography and MRI
Chondroblastoma Pathology: Overview, Clinical Features, Radiography and MRI (emedicine.medscape.com)
Chondroblastoma Treatment & Management: Medical Therapy, Surgical Therapy, Complications
Chondroblastoma Treatment & Management: Medical Therapy, Surgical Therapy, Complications (emedicine.medscape.com)
Wheeless' Textbook of Orthopaedics
Wheeless' Textbook of Orthopaedics (wheelessonline.com)
Jun 1985 - Volume 67 - Issue 5 : JBJS
Jun 1985 - Volume 67 - Issue 5 : JBJS (journals.lww.com)
Chondroblastoma | Children's Hospital of Philadelphia
Chondroblastoma | Children's Hospital of Philadelphia (chop.edu)
Benign Bone Tumors and Cysts - Musculoskeletal and Connective Tissue Disorders - Merck Manuals Professional Edition
Benign Bone Tumors and Cysts - Musculoskeletal and Connective Tissue Disorders - Merck Manuals Professional Edition (merckmanuals.com)
Https://www.medicalnewstoday.com/articles/320273.php
Https://www.medicalnewstoday.com/articles/320273.php (medicalnewstoday.com)
April 1962 - Volume 44 - Issue 3 : JBJS
April 1962 - Volume 44 - Issue 3 : JBJS (journals.lww.com)
Dr. James Wittig, MD - Hackensack, NJ - Orthopedic Oncology & Surgical Oncology | Healthgrades.com
Dr. James Wittig, MD - Hackensack, NJ - Orthopedic Oncology & Surgical Oncology | Healthgrades.com (healthgrades.com)
Giant Cell Tumor of Bone: Practice Essentials, Epidemiology, Prognosis
Giant Cell Tumor of Bone: Practice Essentials, Epidemiology, Prognosis (emedicine.medscape.com)
Differential Diagnosis: Knee pain, Inability to bear weight
Differential Diagnosis: Knee pain, Inability to bear weight (visualdx.com)
Bone Tumors Ger | Metastasis | Bone
Bone Tumors Ger | Metastasis | Bone (scribd.com)
Benign Tumors: MedlinePlus
Benign Tumors: MedlinePlus (medlineplus.gov)
Bone Diseases | MedlinePlus
Bone Diseases | MedlinePlus (medlineplus.gov)
Fibula : Wheeless' Textbook of Orthopaedics
Fibula : Wheeless' Textbook of Orthopaedics (wheelessonline.com)
Community Academic Profiles - Faculty & Researchers - Stanford Medicine
Community Academic Profiles - Faculty & Researchers - Stanford Medicine (med.stanford.edu)
Free Medical Flashcards about CPC-Musculoskeletal
Free Medical Flashcards about CPC-Musculoskeletal (studystack.com)
Chondroblastoma | Cooper University Health Care
Chondroblastoma | Cooper University Health Care (cooperhealth.org)
XXI - Musculoskeletal System Flashcards by Elijah Abuan | Brainscape
XXI - Musculoskeletal System Flashcards by Elijah Abuan | Brainscape (brainscape.com)
Associate Professor Melville Da Cruz - The University of Sydney
Associate Professor Melville Da Cruz - The University of Sydney (sydney.edu.au)
History of Pathology
History of Pathology (massgeneral.org)
Tumors and Tumorlike Lesions of Bone - Fritz Schajowicz - Häftad (9783642499562) | Bokus
Tumors and Tumorlike Lesions of Bone - Fritz Schajowicz - Häftad (9783642499562) | Bokus (bokus.com)
Last night i fell extremely hard on my knee today it hurts a 9/10 and is badly bruised and swollen.. it is even starting to...
Last night i fell extremely hard on my knee today it hurts a 9/10 and is badly bruised and swollen.. it is even starting to... (healthtap.com)
Diagnostic Pathology: Bone. Edition No. 2 - Research and Markets
Diagnostic Pathology: Bone. Edition No. 2 - Research and Markets (researchandmarkets.com)
Research - CheckOrphan
Research - CheckOrphan (checkorphan.org)