Chondroblastoma: A usually benign tumor composed of cells which arise from chondroblasts or their precursors and which tend to differentiate into cartilage cells. It occurs primarily in the epiphyses of adolescents. It is relatively rare and represents less than 2% of all primary bone tumors. The peak incidence is in the second decade of life; it is about twice as common in males as in females. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1846)Curettage: A scraping, usually of the interior of a cavity or tract, for removal of new growth or other abnormal tissue, or to obtain material for tissue diagnosis. It is performed with a curet (curette), a spoon-shaped instrument designed for that purpose. (From Stedman, 25th ed & Dorland, 27th ed)Foot Bones: The TARSAL BONES; METATARSAL BONES; and PHALANGES OF TOES. The tarsal bones consists of seven bones: CALCANEUS; TALUS; cuboid; navicular; internal; middle; and external cuneiform bones. The five metatarsal bones are numbered one through five, running medial to lateral. There are 14 phalanges in each foot, the great toe has two while the other toes have three each.Bone Cysts, Aneurysmal: Fibrous blood-filled cyst in the bone. Although benign it can be destructive causing deformity and fractures.Temporal Bone: Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull).Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Femoral NeoplasmsTarsal Bones: The seven bones which form the tarsus - namely, CALCANEUS; TALUS; cuboid, navicular, and the internal, middle, and external cuneiforms.Skull Neoplasms: Neoplasms of the bony part of the skull.Humerus: Bone in humans and primates extending from the SHOULDER JOINT to the ELBOW JOINT.Giant Cell Tumor of Bone: A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Shoulder Fractures: Fractures of the proximal humerus, including the head, anatomic and surgical necks, and tuberosities.Bone Cysts: Benign unilocular lytic areas in the proximal end of a long bone with well defined and narrow endosteal margins. The cysts contain fluid and the cyst walls may contain some giant cells. Bone cysts usually occur in males between the ages 3-15 years.Arthrodesis: The surgical fixation of a joint by a procedure designed to accomplish fusion of the joint surfaces by promoting the proliferation of bone cells. (Dorland, 28th ed)Ilizarov Technique: A bone fixation technique using an external fixator (FIXATORS, EXTERNAL) for lengthening limbs, correcting pseudarthroses and other deformities, and assisting the healing of otherwise hopeless traumatic or pathological fractures and infections, such as chronic osteomyelitis. The method was devised by the Russian orthopedic surgeon Gavriil Abramovich Ilizarov (1921-1992). (From Bull Hosp Jt Dis 1992 Summer;52(1):1)ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.BerlinGermanyPatella: The flat, triangular bone situated at the anterior part of the KNEE.Connective Tissue Diseases: A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.Osteochondroma: A cartilage-capped benign tumor that often appears as a stalk on the surface of bone. It is probably a developmental malformation rather than a true neoplasm and is usually found in the metaphysis of the distal femur, proximal tibia, or proximal humerus. Osteochondroma is the most common of benign bone tumors.Ehlers-Danlos Syndrome: A heterogeneous group of autosomally inherited COLLAGEN DISEASES caused by defects in the synthesis or structure of FIBRILLAR COLLAGEN. There are numerous subtypes: classical, hypermobility, vascular, and others. Common clinical features include hyperextensible skin and joints, skin fragility and reduced wound healing capability.Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.Osteolysis: Dissolution of bone that particularly involves the removal or loss of calcium.Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.Radiology: A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease.Physician Assistants: Health professionals who practice medicine as members of a team with their supervising physicians. They deliver a broad range of medical and surgical services to diverse populations in rural and urban settings. Duties may include physical exams, diagnosis and treatment of disease, interpretation of tests, assist in surgery, and prescribe medications. (from http://www.aapa.orglabout-pas accessed 2114/2011)Bone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.Vasculitis, Central Nervous System: Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61)Identity Crisis: Chaotic concept of self wherein one's role in life appears to be an insoluble dilemma often expressed by isolation, withdrawal, rebellion and extremism.Knee Joint: A synovial hinge connection formed between the bones of the FEMUR; TIBIA; and PATELLA.Mobile Applications: Computer programs or software installed on mobile electronic devices which support a wide range of functions and uses which include television, telephone, video, music, word processing, and Internet service.Biometric Identification: A method of differentiating individuals based on the analysis of qualitative or quantitative biological traits or patterns. This process which has applications in forensics and identity theft prevention includes DNA profiles or DNA fingerprints, hand fingerprints, automated facial recognition, iris scan, hand geometry, retinal scan, vascular patterns, automated voice pattern recognition, and ultrasound of fingers.Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)Knee: A region of the lower extremity immediately surrounding and including the KNEE JOINT.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Cellular Phone: Analog or digital communications device in which the user has a wireless connection from a telephone to a nearby transmitter. It is termed cellular because the service area is divided into multiple "cells." As the user moves from one cell area to another, the call is transferred to the local transmitter.Computers, Handheld: A type of MICROCOMPUTER, sometimes called a personal digital assistant, that is very small and portable and fitting in a hand. They are convenient to use in clinical and other field situations for quick data management. They usually require docking with MICROCOMPUTERS for updates.History, 17th Century: Time period from 1601 through 1700 of the common era.History, 18th Century: Time period from 1701 through 1800 of the common era.History, 19th Century: Time period from 1801 through 1900 of the common era.United States Virgin Islands: A group of islands in the Lesser Antilles in the West Indies, the three main islands being St. Croix, St. Thomas, and St. John. The capital is Charlotte Amalie. Before 1917 the U.S. Virgin Islands were held by the Danish and called the Danish West Indies but the name was changed when the United States acquired them by purchase.Medical Oncology: A subspecialty of internal medicine concerned with the study of neoplasms.General Surgery: A specialty in which manual or operative procedures are used in the treatment of disease, injuries, or deformities.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.

Chondroblastoma of the temporal bone: a clinicopathologic study of five cases. (1/41)

Chondroblastoma is a rare benign bone tumor. It commonly affects the epiphysis of long bones during the second and third decades of life. Chondroblastoma of the temporal bone is extremely rare. We reviewed five cases of chondroblastoma arising in the temporal bone. Four cases were female and one was male. The ages ranged from 41 to 60 years (mean, 53.6 years). All cases involved the temporal bone. Three involved the left side and two the right. Chief complaints were long-standing localized pain and hearing difficulty. A sharply demarcated lobulated mass was the main radiological finding. Microscopic findings were those of chondroblastoma of usual locations. Two cases showed aneurysmal bone cyst-like areas. Immunohistochemical studies for CD34, CD99, S-100 protein and cytokeratin were performed. Tumor cells were diffusely positive for S-100 protein in three cases and weakly positive for cytokeratin in one case. CD34 and CD99 were negative in all cases. In summary, chondroblastoma of the temporal bone is rare and occurs in older age group than reported cases of chondroblastoma of the usual location in the literature.  (+info)

Extendible replacements of the proximal tibia for bone tumours. (2/41)

Limb salvage is now customary in the treatment of primary bone tumours. The proximal tibia is a frequent site for these neoplasms but reconstruction, especially in children, is a formidable challenge. We reviewed 20 children with extendible replacements of the proximal tibia, all with a minimum follow-up of five years. Five died from their disease and, of the remaining 15, four had above-knee amputations for complications. Infection occurred in seven patients; in five it was related to the lengthening procedure. Aseptic loosening is inevitable in the younger children and only two have avoided a revision, amputation or other major complication; both were aged 12 years at the time of the initial surgery. Despite this, 11 children are alive with a functioning leg and a mean Musculoskeletal Tumour Society functional score of 83%. The lengthening mechanisms used in our series required extensive open operations. We are now using a simpler, minimally invasive, technique which we hope will decrease the incidence of complications. At present, the use of extendible prostheses of the proximal tibia remains an experimental procedure.  (+info)

h-Caldesmon as a specific marker for smooth muscle tumors. Comparison with other smooth muscle markers in bone tumors. (3/41)

Caldesmon is a protein widely distributed in smooth and non-smooth muscle cells and is thought to regulate cellular contraction. Its isoform, high-molecular-weight caldesmon (h-CD), was demonstrated to be specific for smooth muscle cells and smooth muscle tumors of the soft tissue and to never be expressed in myofibroblasts. We performed an immunohistochemical study to examine h-CD expression in the following bone tumors: conventional and non-conventional osteosarcoma, 13; malignant fibrous histiocytoma of bone, 5; giant cell tumors of bone, 5; chondroblastoma, 3; metastatic leiomyosarcoma, 2; and rhabdomyosarcoma, 1. Frequent immunoreactivity for muscle actin (alpha-smooth muscle actin or muscle-specific actin) was seen in 11 of 13 osteosarcomas and all other tumors, whereas h-CD was expressed intensely only in 2 leiomyosarcomas. h-CD is considered a specific and useful marker to distinguish smooth muscle tumor from bone tumors with myoid differentiation.  (+info)

Benign chondroblastoma of bone. Report of a case. (4/41)

A benign chondroblastoma of bone is reported. It was unusual because it occurred in an old lady, in a toe, and it was not painful and radiologically resembled a chondroma. The coarsely lobulated tumour showed a varied microscopic appearance, but it consisted chiefly of closely packed sheets of small, round polygonal or fusiform cells. There was some calcification present. The literature is reviewed.  (+info)

Chondroblastoma of a metacarpal bone mimicking an aneurysmal bone cyst: a case report and a review of the literature. (5/41)

Chondroblastoma of the metacarpal bone has been extremely rare and only seven cases have been reported in the English literature. Here we reported the eighth case of a chondroblastoma that developed on the first metacarpal bone of the right hand of a 21-year-old man. Radiographs showed an expansile osteolytic lesion with a multilocular appearance. In MR images, the lesion showed low intensity in T1 and high intensity in T2-weighted images with multiple fluid-fluid levels, which are findings resembling those of an aneurysmal bone cyst. From the pathological findings, however, it was recognized as a chondroblastoma with aneurysmal bone cyst-like change. Good clinical results was obtained by the subtotal resection of the metacarpal bone with a columnar-shaped iliac bone graft.  (+info)

Coexisting chondroblastoma and osteochondroma: a case report. (6/41)

The coexistence of two different types of benign cartilaginous tumours of bone in the same patient has not been reported in literature. We report a case in which a sixteen-year-old male had a benign chondroblastoma of the proximal left humerus and an osteochondroma of the distal left femur. Both originated at the same time and had a progressive increase in size with growth.  (+info)

Chondroblastoma of the temporal base with high mitotic activity. (7/41)

A 24-year-old man presented with a rare chondroblastoma of the temporal base manifesting as local pain accompanied by difficulty in opening the mouth. Gross total removal was achieved at initial surgery, but the tumor demonstrated rapid and destructive regrowth from a very small residual volume without definite histological malignant transformation. Growth activity estimated by MIB-1 staining increased spontaneously from 2.5% at the initial operation to 18.7% at recurrence. Further extensive radical tumor removal by surgeons from multiple disciplines was performed. The patient has been free of recurrence for 3 years without radiotherapy. Chondroblastoma of the temporal bone is widely accepted as a benign tumor and regrowth after gross total removal is very rare. However, some cases of chondroblastoma have potentially high mitotic activity.  (+info)

Skull base chondroblastoma: a case report. (8/41)

Chondroblastoma is a rare tumor of the skull. Temporal bone is the commonest site of involvement in the skull. We present a thirty one year old man who presented with painless swelling over the left temporal bone, which was near totally excised after preoperative embolization. Management of this unusual tumor and its complications are discussed.  (+info)

*Chondroblastoma

"Chondroblastoma." Human Pathology 24.9 (1993): 944-949. Web. 6 Dec. 2015. Chondroblastoma- Medscape Chondroblastoma- James C. ... "Chondroblastoma of Bone." Human Pathology 20.10 (1989): 965-976. Web. 5 Dec. 2015. Damron, Timothy A. "Chondroblastoma." ... There is no indication of a racial predilection for chondroblastoma. The etiology of chondroblastoma is uncertain, as there is ... or biological activity of the chondroblastoma, respectively. Chondroid differentiation is a common feature of chondroblastoma. ...

*Emile Riachi

Khalil (1980). "Benign chondroblastoma. A case report and review of the literature". Le Journal medical libanais. the Lebanese ...

*Epiphysis

Epiphyseal lesions include chondroblastoma and giant-cell tumor. Long bone Longitudinal section of head of left humerus. ...

*H3F3B (gene)

Somatic mutations in the H3F3B gene are associated with chondroblastoma. A rare de novo germline mutation of the H3F3B gene ( ... "Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone". Nature Genetics. 45 (12): 1479- ...

*H3F3A

Mutations in H3F3A and H3F3B are also found in chondroblastoma and giant cell tumor of bone. GRCh38: Ensembl release 89: ... Dec 2013). "Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone". Nat Genet. 45 (12 ...

*Giant-cell tumor of bone

These include, aneurysmal bone cyst, chondroblastoma, simple bone cyst, osteoid osteoma, osteoblastoma, osteosarcoma, giant- ...

*Aneurysmal bone cyst

An aneurysmal bone cyst can arise from a pre-existing chondroblastoma, a chondromyxoid fibroma, an osteoblastoma, a giant cell ...

*Blastoma

... chondroblastoma is composed of cells resembling the precursor of chondrocytes. Many types of blastoma have been linked to a ...

*List of diseases (C)

... insufficiency Cholesterol ester storage disease Cholesterol esterification disorder Cholesterol pneumonia Chondroblastoma ...

*List of MeSH codes (C04)

... chondroblastoma MeSH C04.557.450.565.265 --- chondroma MeSH C04.557.450.565.265.270 --- chondromatosis MeSH C04.557.450.565.280 ...

*Index of trauma & orthopaedics articles

Chondroblastoma - Chondrocyte - Chondrogenesis - Chondromalacia patellae - Chondromyxoid fibroma - Chondrosarcoma - Chopart's ...

*International Classification of Diseases for Oncology

NOS Chondromatous giant cell tumor Codman tumor M9230/3 Chondroblastoma, malignant M9231/3 Myxoid chondrosarcoma M9240/3 ... chondroma Periosteal chondroma M9221/3 Juxtacortical chondrosarcoma Periosteal chondrosarcoma M9230/0 Chondroblastoma, ...
cellular. + 381 64 1924274. Abstract. Chondroblastoma is a rare, usually benign, tumour and represent 1% of primary bone tumours. Skull base chondroblastomas are extremely rare, most frequently located in the squamous part of the temporal bone, as reviewed in the literature. The authors report the first case of chondroblastoma ethmoid-spheno-petro-clival associated with epidural abcces that was treated through curretage of the lesion, and drainage of the abccess and antibiotic treatment. The transmaxillar approach is performed: Lefort one and sagittal maxillar osteotomy. Result of intervention was exelent and no complications trancurred. Key words. spheno-petro-clival chondroblastoma, transfacial approach, curettage. References. ...
Chondroblastoma is a rare tumor, representing only 1-3% of all primary bone tumors, with local pain and swelling lasting for several months as the most important symptoms. It is usually seen as a lytic lesion involving the epiphysis with a thin border of sclerosis and central punctuate calcification in half of the cases in radiographs. It usually causes expansion or enlargement in the affected site. Primary patella lesions are categorized into benign and malignant tumors and metabolic disorders. Giant cell tumor is the most likely differential diagnoses with tumors of the patella. Patella is a relative uncommon site for chondroblastoma.Most of cases of chondroblastoma in patella reported in literature are treated with patellectomy.We treated a large chondroblastic lesion in patella of an 22 year old male with curettage, burring and bone graft and the result was satisfactory after 8 months postoperation,with complete consolidation of new bone on radiographs, absence of pain and full range of knee ...
Sometimes called Codmans tumor, a chondroblastoma is a rare type of benign (noncancerous) bone tumor that originates from cartilage. Cartilage is the specialized, gristly connective tissue and the tissue from which most bones develop. Cartilage plays an important role in the growth process. There are many different types of cartilage that are present throughout the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee.. Chondroblastoma is a rare type of bone tumor that can affect people of all ages. It is, however, most common in children and young adults. This type of tumor is also more common in males than females.. ...
Sometimes called Codmans tumor, a chondroblastoma is a rare type of benign (noncancerous) bone tumor that originates from cartilage. Cartilage is the specialized, gristly connective tissue and the tissue from which most bones develop. Cartilage plays an important role in the growth process. There are many different types of cartilage that are present throughout the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee.. Chondroblastoma is a rare type of bone tumor that can affect people of all ages. It is, however, most common in children and young adults. This type of tumor is also more common in males than females.. ...
A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly connective tissue from which most bones develop. It plays an important role in the growth process. There are many different types of cartilage in the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. It is also called Codmans tumor. Chondroblastoma can affect people of all ages. But, its most common in children and young adults. Its also more common in males than females. ...
Diagnosis of benign chondroblastoma (costs for program #275514) ✔ Charite University Hospital Berlin ✔ Department of Musculoskeletal Surgery ✔ BookingHealth.com
Diagnosis of benign chondroblastoma (costs for program #219337) ✔ Academic Hospital Cologne-Holweide ✔ Department of Internal Medicine and Gastroenterology ✔ BookingHealth.com
Discussion. Chondroblastomas are rare representing less than 1% of all benign bone tumours1-16 but one author did have the incidence at 5%, possibly only including paediatric bone tumours.17 They arise in the epiphyseal areas of long bones as well as in the apophyses.2-5,7,9-21 Some then extend into the metaphysis.2,3,13,21,22 They occur in the second decade -95% of cases between 5 and 25 years of age.2,6,8,9,11,12,15,21 They appear in males with a ratio of 2-3:1.1,4-11,15-18. They occur mostly in the proximal tibia,7 proximal humerus and proximal femur13,15 as well as in flat bones (34%).3 Seventy-two per cent are found in the lower extremity - 50% around the knee9,19 and 33% in the femur.4 Twenty per cent are found in the humerus9 - 90% of which are in the proximal humerus.4,7 Ten per cent are also found in the small bones of the hands and feet.19 It is the most common tumour of the patella.19 Some say the most frequent site is the proximal humerus.6,11 Some also describe the upper end of the ...
A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly connective tissue from which most bones develop. It plays an important role in the growth process. There are many different types of cartilage in the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. It is also called Codmans tumor....more ...
A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly connective tissue from which most bones develop. It plays an important role in the growth process. There are many different types of cartilage in the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. It is also called Codmans tumor....more ...
A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly connective tissue from which most bones develop. It plays an important role in the growth process. There are many different types of cartilage in the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. It is also called Codmans tumor....more ...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Behjati Sam, , Tarpey Patrick Campbell Peter, J., Presneau, Nadège, Pillay Nischalan, , Van Loo Peter Hassan A Bassim, , Wedge David C., , Cooke, S.L., Gundem, G., Davies, H., Nik-Zainal, S., Martin, S., McLaren, S., Goody, V., Robinson, B., Butler, A., Teague, J.W., Halai, D., Khatri, B., Myklebost, O., Baumhoer Daniel, , Jundt Gernot, , Hamoudi Rifat Wedge David, C., Tirabosco, R., Amary, M.F., Futreal, P.A., Stratton, M.R., Campbell Peter J., , Flanagan, A.M., Scheipl Susanne, and Goodie Victoria, (2013) Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone. Nature Genetics, 45 (12). pp. 1479-1482 ...
TY - JOUR. T1 - Histone 3.3 Mutations in Giant Cell Tumor and Giant Cell-Rich Sarcomas of Bone.. AU - Righi, Alberto. AU - Mancini, Irene. AU - Gambarotti, Marco. AU - Picci, Piero. AU - Gamberi, Gabriella. AU - Marraccini, Cristina. AU - Tos, Angelo Paolo Dei. AU - Simi, Lisa. AU - Pinzani, Pamela. AU - Franchi, Alessandro. PY - 2017/9. Y1 - 2017/9. N2 - Mutually exclusive histone 3.3 gene mutations have been recognized in chondroblastoma and giant cell tumor of bone (GCTB), which may be useful for differential diagnostic purposes in morphologically ambiguous cases. While over 90% of GCTB presents histone 3.3 variants exclusively in the H3F3A gene, chondroblastoma is mutated mainly in H3F3B. In this study we examined a series of giant cell rich primary bone tumors, aiming to evaluate the possible diagnostic role of histone 3.3 mutations in the differential diagnosis between GCTB and giant cell rich sarcomas. Sixteen cases of non-metastatic GCTB, 9 GCTB with lung metastases, and 35 giant ...
Giant cell tumors (GCTs) are common benign bone tumors also known as osteoclastomas. They arise from metaphysis and extends into the epiphysis of the long bones. The lesions usually shows narrow zone of transition, thin cortex, no sclerosis. Differentials include chondroblastoma, aneurysmal bone cyst and enchondroma.. ...
... , Authors: Salvatore Romeo, Pancras CW Hogendoorn. Published in: Atlas Genet Cytogenet Oncol Haematol.
Pigmented Villonodular Synovitis Drug market studies the competitive landscape read of the business. The Pigmented Villonodular Synovitis Drug report conjointly includes development plans and policies at the side of producing processes. the foremost regions concerned in Pigmented Villonodular Synovitis Drug Market square measure (United States, EU, China, and Japan).. Get Sample Copy of Report Here: @ www.e-marketresearch.com/request-sample-23250.html. Producers Analysis and prime Sellers of world Pigmented Villonodular Synovitis Drug Market 2019: Bristol-Myers Squibb Co, F. Hoffmann-La Roche Ltd, Novartis AG, Plexxikon Inc. The Pigmented Villonodular Synovitis Drug report will the thorough study of the key business players to grasp their business methods, annual revenue, company profile and their contribution to the world Pigmented Villonodular Synovitis Drug market share. numerous factors of the Pigmented Villonodular Synovitis Drug business just like the offer chain state of affairs, business ...
Pigmented villonodular synovitis (PVNS) is an idiopathic proliferative synovial process composed of two predominant cell types: mononuclear histiocytic cells and giant cells. This lesion can be locally invasive and can result in bone cyst formation and late cartilage and bone loss. Because metalloproteinases have been implicated in the joint destruction occurring in inflammatory arthritis and in the ability of certain tumors to invade adjacent tissues, their presence in PVNS was determined. Synovial tissue samples were collected at surgical synovectomy from the knees of 10 patients with a prior histological diagnosis of PVNS. Pigmented villonodular synovitis synovium was examined for the presence of the metalloproteinases collagenase and stromelysin. Messenger RNA (mRNA) for collagenase and stromelysin was present in all patient samples, although in varying amounts. In situ hybridization studies on synovial tissue sections identified synovial lining cells as the predominant cells expressing these
Pigmented villonodular synovitis (PVNS) is a joint disease characterized by inflammation and overgrowth of the joint lining. It usually affects the hip or knee. It can also occur in the shoulder, ankle, elbow, hand or foot. In PVNS the lining of the joint, called the synovium, becomes swollen and grows. This growth harms the bone next to the joint. The lining also makes extra fluid that can cause swelling and make movement painful. PVNS is idiopathic, it doesnt seem to run in families or be caused by certain jobs or activities. Surgery can help but, even with treatment, PVNS comes back about half the time. If the pain remains then radiation therapy may help. In the worst cases the joint must be replaced. In general, pigmented villonodular synovitis often manifests initially as sudden onset, unexplained joint swelling and pain; the joint swelling is disproportionate to the amount of pain the patient feels at first. Decreased motion and increased pain occur as the disorder progresses as well as ...
Plexxikon, a member of the Daiichi Sankyo Group, announced today promising, proof-of-concept Phase 1 extension clinical data with PLX3397 in pigmented villonodular synovitis (PVNS), a type of rare, often locally aggressive, musculoskeletal neoplasm that arises from the soft tissues of joints and tendons. Interim data from this ongoing trial show that all evaluable patients treated with PLX3397 achieved either partial responses or stable disease. PLX3397 is a novel, oral small molecule that potently and selectively inhibits CSF1R, KIT and oncogenic FLT3 kinases, which play important roles in cancer. CSF1R, in particular, has been shown to be a primary driver in PVNS. These data are being released today as part of the American Society of Clinical Oncology (ASCO) 50th Annual Meeting Press Program. More detailed data will be presented at the ASCO 50th Annual Meeting, being held May 31-June 3 in Chicago.. The data come from an extension cohort of a multicenter Phase 1 clinical study in solid tumors ...
HealthTap: Doctor answers on Symptoms, Diagnosis, Treatment, and More: Dr. Krauser on alternative treatments for pigmented villonodular synovitis: Start with oral antiinflammatory medications, such as aleve (naproxen) or advil. A steroid taper would be the next step, or an injection into the hip with a steroid medication could be performed.
My Misery : A true, personal story from the experience, I Have Pigmented Villonodular Synovitis. I am 26 years old and have been diagnosed with PVNS in my left hip for the last 5 years. I remember the symptoms started back when I was 14 years old. I had my first synovectomy in 2005 at the age of...
Pvns ? You Couldnt Make This Disease Up. : A true, personal story from the experience, I Have Pigmented Villonodular Synovitis. Hi Simon here, 45, diagnosed 4 weeks ago, had an arthroscopic synovectomy last Monday.. Went well, up and walking. I normally post on the facebook group pvns is pants.. I guess Im looking to find a...
title:Radiotherapy for Pigmented Villonodular Synovitis: A Case Report. Author:Navin Nayan, Vikas K Jagtap. Keywords:Radiotherapy, PVNS (Pigmented Villonodular Synovitis), Surgery. Type:Case report. Abstract:This is a case report of a 13 year old boy who has been operated for Pigmented Villonodular Synovitis (PVNS) and treated with adjuvant post-operative radiotherapy for incomplete surgical resection. This report mainly highlights the role of radiotherapy in managing this rare benign condition with emphasis on improving local control rates with functional joint preservation and avoiding repeated surgeries.. ...
Pignmented villonodular synovitis or PVNS is a benign tumor in the joint. Learn about the symptoms PVNS and treatment options for PVNS.
Logical Images, Inc. d/b/a VisualDx (hereinafter "VisualDx", "we", "us", or "our") has created this Acceptable Use Policy, Medical Disclaimer, & Copyright Notice (this "Notice") to inform you (hereinafter "you", "your", or "yourself") as a purchaser of a license for and/or user of the software hosted by VisualDx known as VisualDx (the "Software") of certain important terms and conditions set forth in the VisualDx End User License Agreement that governs your license for and/or use of the Software (the "EULA"). This Notice is subject to all of the terms and conditions set forth in the EULA and does not replace or limit it in anyway. You should read the EULA in detail prior to purchasing a license for or using the Software to make sure you understand and agree to its terms and conditions. Nothing in this Notice will (a) expand your rights or VisualDx′s obligations under the EULA or (b) modify or otherwise affect any terms and conditions of the EULA or the rights of the parties under the EULA. In ...
When a blood-filled growth occurs in the bones of the arms, legs, skull, trunk or spine, then it might be an aneurysmal bone cyst.
Build: Wed Jun 21 18:33:50 EDT 2017 (commit: 4a3b2dc). National Center for Advancing Translational Sciences (NCATS), 6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-435-0888. ...
TY - JOUR. T1 - Frequent expression of fibroblast growth factor-23 (FGF23) mRNA in aneurysmal bone cysts and chondromyxoid fibromas. AU - Graham, Rondell. AU - Krishnamurthy, Smita. AU - Oliveira, Andre. AU - Inwards, Carrie. AU - Folpe, Andrew L.. PY - 2012/10/1. Y1 - 2012/10/1. N2 - Osteomalacia has multiple aetiologies including the least common, tumour-induced osteomalacia (TIO). Recently, most cases of TIO have been confirmed to be due to phosphaturic mesenchymal tumour of mixed connective tissue type (PMTMCT). Most cases of TIO are the result of production of the fibroblast growth factor-23 (FGF-23) by the tumour. The authors recently showed reverse transcriptase PCR (RT-PCR) for FGF-23 to be valuable in the diagnosis of PMTMCT. However, the authors also noted FGF-23 expression in some cases of aneurysmal bone cyst (ABC) and chondromyxoid fibroma (CMF). For the present study, the authors studied FGF-23 expression by RT-PCR in 19 cases of ABC and eight cases of CMF, all with typical ...
The global Pigmented Villonodular Synovitis Drug market is valued at USD XX million in 2017 and is expected to reach USD XX million by the end of 2025, growing at a CAGR of XX% between 2018...
TY - JOUR. T1 - Aneurysmal bone cyst involving the lunate. AU - Mankin, K. P.. AU - Bischoff, R. J.. AU - Gelberman, R. H.. AU - Rosenberg, Andrew. PY - 1995/1/1. Y1 - 1995/1/1. N2 - Aneurysmal bone cysts are rare lesions which even more rarely involve the bones of the hand. We report a case of a cyst involving the lunate which was initially mistaken for interosseous ganglion. Due to delay in diagnosis, marked destruction of the lunate occurred, necessitating excision and scapho-capitate arthrodesis. Although rare, aneurysmal bone cysts should be included in the differential diagnosis and ruled out prior to embarking on a course of treatment.. AB - Aneurysmal bone cysts are rare lesions which even more rarely involve the bones of the hand. We report a case of a cyst involving the lunate which was initially mistaken for interosseous ganglion. Due to delay in diagnosis, marked destruction of the lunate occurred, necessitating excision and scapho-capitate arthrodesis. Although rare, aneurysmal bone ...
Chondromyxoid fibroma is a rare benign tumor of cartilaginous origin with myxoid and fibrous components. It accounts for approximately 1% of bone tumors. Metaphysis of long bones is the most common location of this tumor. However, there a few case reports of this tumor arising from epiphysis of short tubular bones of the hand and feet. An 11-year-old girl presented to our OPD with complaints of pain and a gradually progressive swelling of the right great toe. On examination, the swelling was diffuse with no signs of inflammation. X-ray examination revealed a well-defined, longitudinally oval lytic lesion in the right distal phalanx of great toe, involving the growth plate and, eroding the medial cortex. Computed tomography (CT) scan did not show any evidence of calcification, septations or involvement of soft tissue. Open biopsy and curettage was done and the specimen was sent for histopathological examination. Histopathological examination (HPE) showed a lobular pattern consisting of myxomatous
In the single dose Part A of the study, patients receive 1 dose of of 10 mg/kg MCS110 administered i.v. on Day 1.. In the multiple dose Part B patients receive up to 6 doses of 10 mg/kg MCS110 administered i.v. once every 4 weeks starting at Day 1, or at Day 29 if the first dose received was placebo.. In the multiple dose Part C patients receive up to 6 doses of 3 mg/kg or 5 mg/kg or 10 mg/kg MCS110 administered i.v. once every 4 weeks starting at Day 1. ...
Aneurysmal bone cyst. X-ray showing an aneurysmal bone cyst (dark patch, upper left) on the lower fibula (calf bone) of a patients leg. This cyst is a lesion on the bone which has a thin wall containing blood filled cyst cavities. A giant cell tumour is the most common cause, although it may be due to an injury of the bone. - Stock Image C003/6331
In the hip, bone lesions typically develop at the junction of the femoral head and neck, and acetabulum. Additionally, erosions are more commonly seen than in the knee due to the tight capsule of the hip joint.. ...
Purpose of the study Case report of a five-year-old boy presenting with a painless swelling of the left knee with decreased range of motion ...
Jan 16, 2018. PARIS - The Latest on Airbus (all times local): 9:50 a.m. Airbus says it sold more than 1,100 planes last year, outselling rival Boeing thanks to a raft of end-of-year deals and a growing global economy and travel demand. The European planemaker reported Monday that it delivered 718 planes in 2017, fewer than Boeings 763 but a record for Airbus. Outgoing CEO Fabrice Bregier said Airbus will speed up production in the coming year, notably of its long-delayed widebody A350, and hopes to out-deliver Boeing by 2020. Bregier acknowledged "challenges" ahead but called them "manageable." Airbus is facing multiple corruption... ...
Aneurysmal bone cysts are rare pseudocysts, commonly seen in long bones and vertebral column. Although a well described and reported lesion, many misconceptions still prevail regarding their etiopathogenesis. Many of the reported cases of jaw aneurys
Learn about the symptoms, diagnosis and treatment of pigmented villonodular synovitis (PVNS), a condition that can cause joint pain and… ...
We went to the Orthopedic Surgeon today and he has a probable prognosis according to the MRI results. He is pretty certain that it is Pigmented Villonodular Synovitis (PVNS). When looking at the MRI, he found swollen tissue around her knee joint, thus producing fluid. This swollen tissue and fluid is what is hindering her walking. The Doctor is planning to get a tissue sample and draw some of the fluid out to test and be 100% certain that its PVNS ...
Free, official coding info for 2020 ICD-10-CM M12.239 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
Dr. Michalski responded: ABC. Aneurysmal bone cysts treated surgically heal in approximately 6 weeks--depending on the personality and location and size of the cyst. If it is fractured/displaced it may take somewhat longer.
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
17-DMAG HCl (Alvespimycin) chondroblastic (36%) and the most frequent major tumor sites had been the 17-DMAG HCl (Alvespimycin) femur (64%) tibia (21%) humerus (7%) and pelvis (7%). All individuals had been treated with high-dose methotrexate doxorubicin and cisplatin with one affected person receiving extra ifosfamide and two individuals receiving extra ifosfamide and etoposide. Extra patient characteristics is seen in Extra file 2: Desk S1. GD2 manifestation The amount of variability between three 3rd party observers was evaluated to be nonsignificant utilizing a two-factor ANOVA without alternative (p?=?0.24) as well as the intraclass relationship coefficient was found to become 0.72 suggesting a good to good Rabbit polyclonal to SHP-2.SHP-2 a SH2-containing a ubiquitously expressed tyrosine-specific protein phosphatase.It participates in signaling events downstream of receptors for growth factors, cytokines, hormones, antigens and extracellular matrices in the control of cell growth,. degree ...
Jan 20, 2018. TRAVERSE CITY, Mich. - Friends and fans are bidding farewell to a speedy border collie that became an internet sensation for keeping a northern Michigan airports runways free of critters. A memorial service for Piper is scheduled for 3 p.m. Saturday at City Opera House in Traverse City. The 9-year-old dog was euthanized Jan. 3 after battling prostate cancer. He became the official wildlife-control canine at Cherry Capital Airport in winter of 2015 - the nemesis of geese, ducks and even snowy owls. Images of Piper on the job, wearing his airport vest, ear muffs and goggles, made their way... ...
Looking for online definition of chondroid in the Medical Dictionary? chondroid explanation free. What is chondroid? Meaning of chondroid medical term. What does chondroid mean?
In this review, we highlight the complexities of the natural history, biology, and clinical management of three intermediate connective tissue tumors: desmoid tumor (DT) or aggressive fibromatosis, tenosynovial giant cell tumor (TGCT) or diffuse-type pigmented villonodular synovitis (dtPVNS), and giant cell tumor of bone (GCTB). Intermediate histologies include tumors of both soft tissue and bone origin and are locally aggressive and rarely metastatic. Some common aspects to these tumors are that they can be locally infiltrative and/or impinge on critical organs, which leads to disfigurement, pain, loss of function and mobility, neurovascular compromise, and occasionally life-threatening consequences, such as mesenteric, bowel, ureteral, and/or bladder obstruction ...
In this review, we highlight the complexities of the natural history, biology, and clinical management of three intermediate connective tissue tumors: desmoid tumor (DT) or aggressive fibromatosis, tenosynovial giant cell tumor (TGCT) or diffuse-type pigmented villonodular synovitis (dtPVNS), and giant cell tumor of bone (GCTB). Intermediate histologies include tumors of both soft tissue and bone origin and are locally aggressive and rarely metastatic. Some common aspects to these tumors are that they can be locally infiltrative and/or impinge on critical organs, which leads to disfigurement, pain, loss of function and mobility, neurovascular compromise, and occasionally life-threatening consequences, such as mesenteric, bowel, ureteral, and/or bladder obstruction ...
USP6 rearrangement is the most common genetic abnormality in primary aneurysmal bone cyst, and SS18 rearrangement has not been previously described in any type of tumor where synovial sarcoma was excluded from the differential diagnosis. We report a case of solid aneurysmal bone cyst in which fluorescence in situ hybridization (FISH) analysis indicated rearrangements of both USP6 and SS18, but histologic features were consistent with aneurysmal bone cyst throughout the lesion. Reverse-transcription polymerase chain reaction (RT-PCR) for the SS18-SSX1 and SS18-SSX2 translocations, identity testing, and SS18 FISH were performed on cytogenetic monolayer cultures and formalin-fixed paraffin-embedded (FFPE) tissue. Genomic microarray, FISH, and immunohistochemistry were performed on follow-up studies of the FFPE specimen. The karyotype was 45,X,add(X)(p11.2),add(4)(q13),add(8)(p21),-13,add(17)(p11.2),add(18)(q11.2) in all 20 cells analyzed from monolayer cultures. The karyotype showed no ...
INTERPRETATION. The pantomograph (Fig. 2) shows a well demarcated ovoid radiolucent lesion in the left body and ascending ramus of the mandible features consistent with a benign neoplasm. The unerupted third molar was displaced mesially. Anincisionalbiopsy was carried out and a histological diagnosis of chondromyxoid fibroma was made. When the tumour was removed, an easily discernible dissection plane was found and the surgeon did not have the clinical impression of malignancy. The whole area was thoroughly curetted. Histological examination of the excised specimen confirmed the initial biopsy. There were no signs of recurrence at follow-up until three years later, when the patient presented with a swelling in the same area as previously. There was no lymphadenopathy. Radiographs showed a radiolucent lesion in the same area, but with less demarcation than the initial lesion (Fig. 3). A hemimandibulectomy was performed and a vitallium splint inserted. At this stage a diagnosis of a mesenchymal ...
Chronic monoarthritis demand an investigation of inflammatory diseases, such as rheumatoid arthritis (RA), infectious diseases like tuberculosis; and other diseases that cause synovitis and joint effusion, such as pigmented villonodular synovitis (PVNS), synovial hemangioma, synovial osteochondromatosis and arborescence lipoma. We report the case of a young patient with chronic right shoulder monoarthritis, whos magnetic resonance imaging (MRI) showed synovitis. Arthroscopy was performed and the biopsy revealed PVNS. Case report: J C M, 15 years-old, female, Caucasian, student. She was sent to a Rheumatologist along with a diagnosis of juvenile idiopathic arthritis (JIA). The patient presented, for one year, a mild pain of insidious onset in her right shoulder, with relief of the symptoms in two days under nonsteroidal anti-inflammatory therapy (NSAIDs). During this year, the patient presented five or six episodes of pain with the same characteristics. No other signs and symptoms were related. ...
Looking for online definition of chondroid bone in the Medical Dictionary? chondroid bone explanation free. What is chondroid bone? Meaning of chondroid bone medical term. What does chondroid bone mean?
There are still some debates regarding the best treatment of Giant Cell Tumor (GCT) of the sacrum. Since GCT of this location is rare, therapeutic strategies are mainly based on the treatment of GCT in other anatomic locations. The objective of this study was to evaluate the oncologic and clinical results of surgical management of sacral GCT with and without local adjuvant therapy. Medical records of 19 patients diagnosed with GCT of the sacrum, were retrospectively reviewed. Sixteen patients were treated by intralesional curettage and three patients with marginal resection. Musculoskeletal tumor society (MSTS) score was used for the evaluation of functional outcome. Prolonged pain was the most common complication after treatment. Mean Pre and post-operative pain based on visual analogue scale (VAS) was 6.1 ± 1.99 and 3.05 ± 1.64, respectively. Postoperative neurologic deficit appeared in six patients. In addition, infection occurred in five patients. One case of spinopelvic instability was also
Summary: A 38-year-old woman presented with a mass on her left hand that had been gradually increasing in size over a 3-year period. Hand radiography was ob...
Dilation and Curettage D&C Definition - Dilation and curettage (D&C) is a surgical procedure to remove tissue from the uterus. A D&C can be performed to...
Learn more about Dilation and Curettage at Sky Ridge Medical Center DefinitionReasons for ProcedurePossible ComplicationsWhat to ExpectCall Your Doctorrevision ...
Ectomesenchymal chondromyxoid tumor (ECT) is a benign intraoral tumor with presumed origin from undifferentiated (ecto)mesenchymal cells. There are some who think it is a myoepithelial tumor type. Derived from ectomesenchymal cells migrating from neural crest (there is immunophenotypic support for this theory). Equivalent to soft tissue myoepithelioma. There is morphologic and immunohisthochemical support for this theory, with some authors advocating interchangeable terms. Patients present with a painless, slow-growing mass usually within the tongue (most commonly the anterior dorsal tongue). There is an intact surface epithelium. Surgical excision is the treatment of choice, with recurrences only when there is incomplete excision. Submucosal circumscribed but not encapsulated nodular mass, often with entrapped muscle bundles at the edge. It may have a gelatinous appearance. Most tumors are small, up to 2 cm (given the confines of the tongue, a larger mass would cause significant clinical ...
Conclusion: This case involved an extraosseous, intradural, four-level subaxial cervical chordoma that demonstrated significant extraspinal extension into the anterior soft tissues of the neck. PMID: 29142772 [PubMed]...
Aneurysmal bone cyst (ABC) has a recurrence rate of between 12% and 71% without en bloc resection or amputation. There is no percutaneous ABC treatment drug regimen demonstrating consistent evidence of bone healing with recurrence of < 12%. Doxycyline has properties that may make it appropriate for percutaneous treatment.. ...
curettage definition: removing muscle or growths from a body hole, including the womb, by scraping with a curette. Also called curettement.; removing undesirable tissue from a body hole utilizing a curette.;…
Looking for curettage? Find out information about curettage. Scraping of the inside of a body cavity or the hollow of an organ with a curet Explanation of curettage
I also posted this on the Students thread coz I am just really sooooo lost and am freaking out right now.:banghead: Hello everyone, I am writing a care plan on hemothorax. My textbooks doesnt
Dilation and curettage (D and C) is a female surgical procedure. It can be used for diagnosis, treatment, or following a miscarriage.

Chondroblastoma -  Health Encyclopedia - University of Rochester Medical CenterChondroblastoma - Health Encyclopedia - University of Rochester Medical Center

Chondroblastoma. What is chondroblastoma? A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage ... How is chondroblastoma treated? The goal for treatment of chondroblastoma is to remove the tumor and prevent damage to the end ... Key points about chondroblastoma Chondroblastoma is a rare type of noncancerous bone tumor that starts from cartilage. It most ... What causes chondroblastoma? The exact cause of chondroblastoma is not known. The tumors are believed to start from immature ...
more infohttps://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=85&ContentID=P00112

NewYork-Presbyterian Queens - ChondroblastomaNewYork-Presbyterian Queens - Chondroblastoma

Chondroblastoma. What is chondroblastoma?. Sometimes called Codmans tumor, a chondroblastoma is a rare type of benign ( ... Treatment for chondroblastoma. Specific treatment for chondroblastoma will be determined by your doctor based on:. *Your age, ... What causes chondroblastoma?. The exact cause of chondroblastoma is not known. The tumors are believed to originate from ... What are the symptoms of chondroblastoma?. Symptoms of chondroblastoma may vary depending on the location of the tumor. The ...
more infohttp://www.nyhq.org/diw/content.asp?pageid=P07413

NewYork-Presbyterian Queens - ChondroblastomaNewYork-Presbyterian Queens - Chondroblastoma

Chondroblastoma. What is chondroblastoma?. Sometimes called Codmans tumor, a chondroblastoma is a rare type of benign ( ... Treatment for chondroblastoma. Specific treatment for chondroblastoma will be determined by your doctor based on:. *Your age, ... What causes chondroblastoma?. The exact cause of chondroblastoma is not known. The tumors are believed to originate from ... What are the symptoms of chondroblastoma?. Symptoms of chondroblastoma may vary depending on the location of the tumor. The ...
more infohttp://www.nyhq.org/diw/Content.asp?PageID=DIW000112&More=OTH&language=Chinese

Diagnosis of benign chondroblastoma: Costs for treatment #275514 in Germany | BookingHealthDiagnosis of benign chondroblastoma: Costs for treatment #275514 in Germany | BookingHealth

Diagnosis of benign chondroblastoma (costs for program #275514) ✔ Charite University Hospital Berlin ✔ Department of ... Charite University Hospital Berlin › Diagnosis of benign chondroblastoma: Costs for treatment #275514 in Germany - ... Diagnosis of benign chondroblastoma,price:{val:0,type:val},extra_service_clinic:[],extra_service:[],translation_ ...
more infohttps://bookinghealth.com/university-hospital-charite-berlin/diagnostic-programs/275514-diagnosis-of-benign-chondroblastoma.html

a Case of a Benign Chondroblastoma of Bone with a Rare Localization]. - Semantic Scholara Case of a Benign Chondroblastoma of Bone with a Rare Localization]. - Semantic Scholar

... a Case of a Benign Chondroblastoma of Bone with a Rare Localization]. by K CHOKANOV et al. ... a Case of a Benign Chondroblastoma of Bone with a Rare Localization].. *. K CHOKANOV. , R D Raichev ... article{CHOKANOV1963aCO, title={[a Case of a Benign Chondroblastoma of Bone with a Rare Localization].}, author={K CHOKANOV and ...
more infohttps://www.semanticscholar.org/paper/a-Case-of-a-Benign-Chondroblastoma-of-Bone-with-a-CHOKANOV-Raichev/faa2ac36efadb6fce850ac9b06713fe64b12c890

Chondroblastoma of the patella treated with curettage and bone grafting - International Journal of Conference ProceedingsChondroblastoma of the patella treated with curettage and bone grafting - International Journal of Conference Proceedings

Chondroblastoma of the patella treated with curettage and bone grafting. jocpadmin April 21, 2014 Chondroblastoma of the ... Patella is a relative uncommon site for chondroblastoma.Most of cases of chondroblastoma in patella reported in literature are ... Chondroblastoma is a rare tumor, representing only 1-3% of all primary bone tumors, with local pain and swelling lasting for ... Chondroblastoma of the patella treated with curettage and bone grafting. I J Orthopaedic Conference Proceedings April 2014;1(2 ...
more infohttp://jocponline.com/chondroblastoma-of-the-patella-treated-with-curettage-and-bone-grafting/

ETHMOID-SPHENO-PETRO-CLIVAL CHONDROBLASTOMA AND ASOCIATED EPIDURAL ABSCES: CASE REPORT / 
ETMOIDNO-SFENO-PETRO-KLIVALNI...ETHMOID-SPHENO-PETRO-CLIVAL CHONDROBLASTOMA AND ASOCIATED EPIDURAL ABSCES: CASE REPORT / ETMOIDNO-SFENO-PETRO-KLIVALNI...

Chondroblastoma-like chondroma of soft tissue: report of the first case in the base of skull. Raparia K, Lin JW, Donovan D, ... Chondroblastoma of the apex portion of petrousal bone. Dran G, Niesar E, Vandenbos F, Noel G, Paquis P, Lonjon M. Childs Nerv ... Chondroblastoma of the skull base. Chrerkaev VA, Korshunov AG, Gasparian TG, Kadasheva AB, Semenova LA, Shishkina LV. Zh Vopr ... Chondroblastoma of the temporal bone: a case series, review, and suggested management strategy. Reid LB, Wong DS, Lyons B. ...
more infohttp://md-medicaldata.com/godina_2016_broj_2_title_09.html

Chondroblastoma | Cooper University Health CareChondroblastoma | Cooper University Health Care

... oncology center offers expert diagnosis and treatment for patients with a rare benign bone tumor called chondroblastoma. ... Symptoms of Chondroblastoma. Symptoms of chondroblastoma may vary depending on where the tumor is located. However, pain in the ... Chondroblastoma, sometimes called Codmans tumor, is a rare type of benign (non-cancerous) bone tumor that is comprised of ... Some of the more common symptoms of chondroblastoma include:. *Pain in the knee, hip, and/or shoulder joint, especially pain ...
more infohttps://www.cooperhealth.org/services/chondroblastoma

Chondroblastoma Pathology: Overview, Clinical Features, Radiography and MRIChondroblastoma Pathology: Overview, Clinical Features, Radiography and MRI

The official designation of a primary bone tumor as a chondroblastoma depends on the histologic finding of foci of chondroid ... Chondroblastoma is a rare benign bone tumor of chondroblast origin that almost always occurs in a primary or secondary site of ... encoded search term (Chondroblastoma Pathology) and Chondroblastoma Pathology What to Read Next on Medscape. Related Conditions ... Chondroblastoma is a rare benign bone tumor of chondroblast origin [1] that almost always occurs in a primary or secondary site ...
more infohttps://emedicine.medscape.com/article/1998441-overview

Chondroblastoma Treatment & Management: Medical Therapy, Surgical Therapy, ComplicationsChondroblastoma Treatment & Management: Medical Therapy, Surgical Therapy, Complications

A chondroblastoma is a rare, usually benign, tumor of bone that accounts for approximately 1% of all bone tumors. In 1931, ... encoded search term (Chondroblastoma) and Chondroblastoma What to Read Next on Medscape. Related Conditions and Diseases. * ... Chondroblastoma Treatment & Management. Updated: Dec 03, 2018 * Author: Timothy A Damron, MD; Chief Editor: Omohodion (Odion) ... RFA for chondroblastoma has been described in several reports, but follow-up has been shorter than for surgical treatment, and ...
more infohttps://emedicine.medscape.com/article/1254949-treatment

Chondroblastoma - WikipediaChondroblastoma - Wikipedia

"Chondroblastoma." Human Pathology 24.9 (1993): 944-949. Web. 6 Dec. 2015. Chondroblastoma- Medscape Chondroblastoma- James C. ... "Chondroblastoma of Bone." Human Pathology 20.10 (1989): 965-976. Web. 5 Dec. 2015. Damron, Timothy A. "Chondroblastoma." ... There is no indication of a racial predilection for chondroblastoma. The etiology of chondroblastoma is uncertain, as there is ... or biological activity of the chondroblastoma, respectively. Chondroid differentiation is a common feature of chondroblastoma. ...
more infohttps://en.wikipedia.org/wiki/Chondroblastoma

Benign chondroblastoma of the occipital bone: case reportBenign chondroblastoma of the occipital bone: case report

Keywords : benign chondroblastoma; occipital bone; cartilaginous tumor; skull. · abstract in Portuguese · text in Portuguese · ... Chondroblastoma arising from the occipital bone is extremely rare. We report the case of a 16 year old girl with a benign ... Benign chondroblastoma is a rare bone tumor of immature cartilage cell derivation. This lesion classically occur at the ends of ... Benign chondroblastoma of the occipital bone: case report. Arq. Neuro-Psiquiatr. [online]. 1995, vol.53, n.4, pp.834-836. ISSN ...
more infohttp://www.scielo.br/scielo.php?script=sci_abstract&pid=S0004-282X1995000500023&lng=en&nrm=iso&tlng=en

Chondroblastoma of the Knee Treated with Resection and Osteochondral Allograft ReconstructionChondroblastoma of the Knee Treated with Resection and Osteochondral Allograft Reconstruction

A. J. Ramappa, F. Y. I. Lee, P. Tang, J. R. Carlson, M. C. Gebhardt, and H. J. Mankin, "Chondroblastoma of bone," The Journal ... S. H. Sohn, S. A. Koh, D. G. Kim et al., "A case of spine origin chondroblastoma metastasis to lung," Cancer Research and ... F. Sailhan, F. Chotel, and R. Parot, "Chondroblastoma of bone in a pediatric population," Journal of Bone and Joint Surgery- ... Chondroblastoma of the Knee Treated with Resection and Osteochondral Allograft Reconstruction. Judd Fitzgerald,1 Cory Broehm,2 ...
more infohttps://www.hindawi.com/journals/crior/2014/543959/

A Massive Chondroblastoma in the Proximal Humerus Simulating Malignant Bone TumorsA Massive Chondroblastoma in the Proximal Humerus Simulating Malignant Bone Tumors

... Ichiro Tonogai,1 Mitsuhiko Takahashi,1 ... Ichiro Tonogai, Mitsuhiko Takahashi, Hiroaki Manabe, et al., "A Massive Chondroblastoma in the Proximal Humerus Simulating ...
more infohttps://www.hindawi.com/journals/crior/2013/673576/cta/

Proximal humerus chondroblastoma with a secondary aneurysmal bone cystProximal humerus chondroblastoma with a secondary aneurysmal bone cyst

Chondroblastoma. In: Human Pathology 1993;24(9):944-49. [ Links ]. 4. Fines BP, Stacy GS. Chondroblastoma imaging. In: Medscape ... Benign chondroblastoma. In: JBJS (Br) 1966;48-B:92-104. [ Links ]. 3. Turcotte RE, Kurt A, Sim FH, Unni KK, McLeod RA. ... Chondroblastoma. In: Journal of Orhtopaedic Surgery 2008; 16(1):84-87. [ Links ]. 14. Suneja R, Grimer RJ, Belthur M, Jeys L, ... Benign chondroblastoma. In: JBJS (Br) 1956;38-A:817-26. [ Links ]. 17. Isler MH, Turcotte RE. Bone tumours in children. In: ...
more infohttp://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1681-150X2012000200010&lng=pt&nrm=iso&tlng=pt

An aggressive chondroblastoma of the knee treated with resection arthrodesis and limb lengthening using the Ilizarov techniqueAn aggressive chondroblastoma of the knee treated with resection arthrodesis and limb lengthening using the Ilizarov technique

Chondroblastoma of bone. J Bone Joint Surg [Am] 2000;82:1140-5. doi: 10.1302/0301-620X.82B8.10791. [PubMed] [Cross Ref] ... Pulmonary metastases from chondroblastoma of the tibia. Report of a case. J Bone Joint Surg [Br] 1973;55(4):848-53. [PubMed] ... Benign chondroblastoma of bone. Report of a case. J Bone Joint Surg [Br] 1975;57(1):78-81. [PubMed] ... Chondroblastoma of the pelvis suggestive of malignancy. J Bone Joint Surg [Am] 1975;57(4):549-51. [PubMed] ...
more infohttp://pubmedcentralcanada.ca/pmcc/articles/PMC2921358/

ChondroblastomaChondroblastoma

... most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the ... A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly ... Chondroblastoma. What is chondroblastoma? A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage ... How is chondroblastoma treated? The goal for treatment of chondroblastoma is to remove the tumor and prevent damage to the end ...
more infohttp://healthlibrary.olmmed.org/Library/DiseasesConditions/Adult/Bone/85,P00112

Surgical Dislocation of the Hip for the Treatment of a Femoral Head Chondroblastoma | International Congress for Joint...Surgical Dislocation of the Hip for the Treatment of a Femoral Head Chondroblastoma | International Congress for Joint...

Chondroblastoma; p 247-64.. *Strong DP, Grimer RJ, Carter SR, Tillman RM, Abudu A. Chondroblastoma of the femoral head: ... Chondroblastoma is a rare tumor that represents 1% to 2% of all primary bone tumors. [1-7] Prior to being defined as a distinct ... Chondroblastoma: a clinical and radiological study of 104 cases. Skeletal Radiol. 1985;14(1):1-9.Crim JR, Gold RH, Mirra JM, ... Surgical Dislocation of the Hip for the Treatment of a Femoral Head Chondroblastoma. A 17-year-old, high-level female athlete ...
more infohttps://icjr.net/articles/surgical-dislocation-of-the-hip-for-the-treatment-of-a-femoral-head-chondroblastoma

Spot Diagnosis: ChondroblastomaSpot Diagnosis: Chondroblastoma

This appearance is consistent with a chondroblastoma. The... ... Chondroblastoma. This 24-years old man had pain in the left ... ABC transformation in a chondroblastoma is not uncommon and the presence of fluid-fluid levels should not prevent us from ... This appearance is consistent with a chondroblastoma. The MRI (Figs. 2, 3) showed a lesion with fluid-fluid levels. Such levels ... You can also see the other examples of a chondroblastoma in the tibial epiphysis and femoral head. ...
more infohttps://bhavin.typepad.com/radiology/2006/06/chondroblastoma_1.html

Chondroblastoma : Bone Cancer Tumors : Tumors of the boneChondroblastoma : Bone Cancer Tumors : Tumors of the bone

Treatment of a Chondroblastoma of Proximal Humerus with Intralesional Curettage Resection, Cryosurgery and Bone Grafting ... Secondary aneurysmal bone cyst frequently correlated with chondroblastoma. *Chondroblastomas have been reported to transform ... there is always a risk of growth plate failure from the chondroblastoma since it usually grows adjacent to the growth plate and ...
more infohttp://www.tumorsurgery.org/tumor-education/bone-tumors/types-of-bone-tumors/chondroblastoma.aspx

Metastatic chondroblastoma with elevated creatine kinase and paraneoplastic neurologic autoimmunity. - Semantic ScholarMetastatic chondroblastoma with elevated creatine kinase and paraneoplastic neurologic autoimmunity. - Semantic Scholar

The association of metastatic chondroblastoma, elevated CK, and an evolving profile of paraneoplastic autoantibodies reveals a ... Locally recurrent chondroblastoma was excised 1 year later. Serum CK was elevated, CRMP-5-IgG was positive, PCA-2 was lower, ... A 17-year-old girl presented with chondroblastoma of the fibula and pulmonary metastases. Serum creatine kinase (CK) was ... Chondroblastoma and chondromyxoid fibroma.. *Camila B R De Mattos, Chanika Angsanuntsukh, Alexandre Arkader, John P Dormans ...
more infohttps://www.semanticscholar.org/paper/Metastatic-chondroblastoma-with-elevated-creatine-Joshi-Anderson/4f3ee1f386ecf7e5d209a0639592b91c666e0347

Surgery: Chondroblastoma | Surgical resection. Treatment in Cologne, Germany | BookingHealthSurgery: Chondroblastoma | Surgical resection. Treatment in Cologne, Germany | BookingHealth

Chondroblastoma , Surgical resection. Treatment in Cologne, Germany ✈ Find the best medical programs at BookingHealth - ✔ ... Surgical resection of benign chondroblastoma #211009. The Department of General, Abdominal and Tumor Surgery deals with the ... Surgical resection of benign chondroblastoma #219183. With a team of 15 physicians having different surgical specialties, the ...
more infohttps://bookinghealth.com/programs/treatment/surgery/benign-chondroblastoma-surgical-resection/germany/cologne

Chondroblastoma of Ventral Skull Base: First Report of a CaseChondroblastoma of Ventral Skull Base: First Report of a Case

We describe the main radiologic and histologic characteristics of chondroblastoma and compare them to those of frequently ... Report of the first case of chondroblastoma involving the sinonasal cavity and ventral skull base, offering a description of ... Chondroblastoma, Endoscopy, Skull base, Bone tumor Introduction. Chondroblastoma is a rare neoplasm of the bone constituting ... Chondroblastoma of Ventral Skull Base: First Report of a Case Ahmad Elkhatib1, Paul Wakely Jr2, Luciano M Prevedello3, Ralph ...
more infohttps://www.clinmedjournals.org/articles/jor/journal-of-otolaryngology-and-rhinology-jor-4-039.php?jid=%0A%09jor

Chondroblastoma             | Genetic and Rare Diseases Information Center (GARD) - an NCATS ProgramChondroblastoma | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program

... information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Chondroblastoma ...
more infohttps://phgkb.cdc.gov/PHGKB/phgHome.action?action=forward&dbsource=cluster&id=26641

Reconstruction with double pedicel fibular graft and ankle arthrodesis for aggressive chondroblastoma in the distal tibia |...Reconstruction with double pedicel fibular graft and ankle arthrodesis for aggressive chondroblastoma in the distal tibia |...

Aggressive chondroblastoma of the distal tibia is rare, and below-knee amputation had been the standard surgical procedure. We ... fibular graft and ankle arthrodesis may be an effective and economical alternative method for aggressive chondroblastoma in the ... Aggressive chondroblastoma of the distal tibia is further rare. For patients with aggressive chondroblastoma, treatments ... At times, chondroblastoma may be aggressive in character. Primary malignant form as well as malignant alteration in the form of ...
more infohttps://wjso.biomedcentral.com/articles/10.1186/s12957-016-0839-z
  • On radiographic images, chondroblastoma is characterized by a well-defined osteolytic lesion involving an epiphysis or secondary ossification center (see the following image). (medscape.com)
  • The authors report the first case of chondroblastoma ethmoid-spheno-petro-clival associated with epidural abcces that was treated through curretage of the lesion, and drainage of the abccess and antibiotic treatment. (md-medicaldata.com)
  • RFA for chondroblastoma has been described in several reports, but follow-up has been shorter than for surgical treatment, and caution is recommended for cases in which the lesions are larger than 2.5 cm and when there is no subchondral bone support. (medscape.com)
  • However, Edel et al found that collagen II, a marker for mature chondrocytes, was expressed in chondroblastoma, supporting the chondroid nature of the neoplasm. (wikipedia.org)
  • The results of Romeo and colleagues favor the view of Edel et al of chondroblastoma being cartilaginous in nature but recognize that any definitive determinations regarding the origin of this neoplasm are not possible because of the plasticity of mesenchymal cells when set into different microenvironments and static approaches used in literature. (wikipedia.org)
  • There are two opposing views on the nature of chondroblastoma, one favoring an osseous origin and the other favoring a cartilaginous origin. (wikipedia.org)
  • The clinical presentation of a chondroblastoma often includes insidious onset of pain, local tenderness, decreased range of motion, and swelling. (icjr.net)
  • We treat more patients with chondroblastoma than any other center in South Jersey. (cooperhealth.org)
  • In search of a targeted therapy for patients with disseminated chondroblastoma or those in need of medical management, Yang et al reported positive effects of targeted inhibition of mTOR (mammalian target of rapamycin) and HIF (hypoxia-inducible factor) pathways in benchtop work with chondroblastoma. (medscape.com)
  • Chondroblastoma shows a predilection towards the male sex, with a ratio of male to female patients of 2:1. (wikipedia.org)
  • Approximately 92% of patients presenting with chondroblastoma are younger than 30 years. (wikipedia.org)
  • We have access to many advanced diagnostic tests that can accurately detect chondroblastoma. (cooperhealth.org)