A usually benign tumor composed of cells which arise from chondroblasts or their precursors and which tend to differentiate into cartilage cells. It occurs primarily in the epiphyses of adolescents. It is relatively rare and represents less than 2% of all primary bone tumors. The peak incidence is in the second decade of life; it is about twice as common in males as in females. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1846)
A scraping, usually of the interior of a cavity or tract, for removal of new growth or other abnormal tissue, or to obtain material for tissue diagnosis. It is performed with a curet (curette), a spoon-shaped instrument designed for that purpose. (From Stedman, 25th ed & Dorland, 27th ed)
The TARSAL BONES; METATARSAL BONES; and PHALANGES OF TOES. The tarsal bones consists of seven bones: CALCANEUS; TALUS; cuboid; navicular; internal; middle; and external cuneiform bones. The five metatarsal bones are numbered one through five, running medial to lateral. There are 14 phalanges in each foot, the great toe has two while the other toes have three each.
Fibrous blood-filled cyst in the bone. Although benign it can be destructive causing deformity and fractures.
Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull).
Tumors or cancer located in bone tissue or specific BONES.
The seven bones which form the tarsus - namely, CALCANEUS; TALUS; cuboid, navicular, and the internal, middle, and external cuneiforms.
Neoplasms of the bony part of the skull.
Bone in humans and primates extending from the SHOULDER JOINT to the ELBOW JOINT.
A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)

Chondroblastoma of the temporal bone: a clinicopathologic study of five cases. (1/41)

Chondroblastoma is a rare benign bone tumor. It commonly affects the epiphysis of long bones during the second and third decades of life. Chondroblastoma of the temporal bone is extremely rare. We reviewed five cases of chondroblastoma arising in the temporal bone. Four cases were female and one was male. The ages ranged from 41 to 60 years (mean, 53.6 years). All cases involved the temporal bone. Three involved the left side and two the right. Chief complaints were long-standing localized pain and hearing difficulty. A sharply demarcated lobulated mass was the main radiological finding. Microscopic findings were those of chondroblastoma of usual locations. Two cases showed aneurysmal bone cyst-like areas. Immunohistochemical studies for CD34, CD99, S-100 protein and cytokeratin were performed. Tumor cells were diffusely positive for S-100 protein in three cases and weakly positive for cytokeratin in one case. CD34 and CD99 were negative in all cases. In summary, chondroblastoma of the temporal bone is rare and occurs in older age group than reported cases of chondroblastoma of the usual location in the literature.  (+info)

Extendible replacements of the proximal tibia for bone tumours. (2/41)

Limb salvage is now customary in the treatment of primary bone tumours. The proximal tibia is a frequent site for these neoplasms but reconstruction, especially in children, is a formidable challenge. We reviewed 20 children with extendible replacements of the proximal tibia, all with a minimum follow-up of five years. Five died from their disease and, of the remaining 15, four had above-knee amputations for complications. Infection occurred in seven patients; in five it was related to the lengthening procedure. Aseptic loosening is inevitable in the younger children and only two have avoided a revision, amputation or other major complication; both were aged 12 years at the time of the initial surgery. Despite this, 11 children are alive with a functioning leg and a mean Musculoskeletal Tumour Society functional score of 83%. The lengthening mechanisms used in our series required extensive open operations. We are now using a simpler, minimally invasive, technique which we hope will decrease the incidence of complications. At present, the use of extendible prostheses of the proximal tibia remains an experimental procedure.  (+info)

h-Caldesmon as a specific marker for smooth muscle tumors. Comparison with other smooth muscle markers in bone tumors. (3/41)

Caldesmon is a protein widely distributed in smooth and non-smooth muscle cells and is thought to regulate cellular contraction. Its isoform, high-molecular-weight caldesmon (h-CD), was demonstrated to be specific for smooth muscle cells and smooth muscle tumors of the soft tissue and to never be expressed in myofibroblasts. We performed an immunohistochemical study to examine h-CD expression in the following bone tumors: conventional and non-conventional osteosarcoma, 13; malignant fibrous histiocytoma of bone, 5; giant cell tumors of bone, 5; chondroblastoma, 3; metastatic leiomyosarcoma, 2; and rhabdomyosarcoma, 1. Frequent immunoreactivity for muscle actin (alpha-smooth muscle actin or muscle-specific actin) was seen in 11 of 13 osteosarcomas and all other tumors, whereas h-CD was expressed intensely only in 2 leiomyosarcomas. h-CD is considered a specific and useful marker to distinguish smooth muscle tumor from bone tumors with myoid differentiation.  (+info)

Benign chondroblastoma of bone. Report of a case. (4/41)

A benign chondroblastoma of bone is reported. It was unusual because it occurred in an old lady, in a toe, and it was not painful and radiologically resembled a chondroma. The coarsely lobulated tumour showed a varied microscopic appearance, but it consisted chiefly of closely packed sheets of small, round polygonal or fusiform cells. There was some calcification present. The literature is reviewed.  (+info)

Chondroblastoma of a metacarpal bone mimicking an aneurysmal bone cyst: a case report and a review of the literature. (5/41)

Chondroblastoma of the metacarpal bone has been extremely rare and only seven cases have been reported in the English literature. Here we reported the eighth case of a chondroblastoma that developed on the first metacarpal bone of the right hand of a 21-year-old man. Radiographs showed an expansile osteolytic lesion with a multilocular appearance. In MR images, the lesion showed low intensity in T1 and high intensity in T2-weighted images with multiple fluid-fluid levels, which are findings resembling those of an aneurysmal bone cyst. From the pathological findings, however, it was recognized as a chondroblastoma with aneurysmal bone cyst-like change. Good clinical results was obtained by the subtotal resection of the metacarpal bone with a columnar-shaped iliac bone graft.  (+info)

Coexisting chondroblastoma and osteochondroma: a case report. (6/41)

The coexistence of two different types of benign cartilaginous tumours of bone in the same patient has not been reported in literature. We report a case in which a sixteen-year-old male had a benign chondroblastoma of the proximal left humerus and an osteochondroma of the distal left femur. Both originated at the same time and had a progressive increase in size with growth.  (+info)

Chondroblastoma of the temporal base with high mitotic activity. (7/41)

A 24-year-old man presented with a rare chondroblastoma of the temporal base manifesting as local pain accompanied by difficulty in opening the mouth. Gross total removal was achieved at initial surgery, but the tumor demonstrated rapid and destructive regrowth from a very small residual volume without definite histological malignant transformation. Growth activity estimated by MIB-1 staining increased spontaneously from 2.5% at the initial operation to 18.7% at recurrence. Further extensive radical tumor removal by surgeons from multiple disciplines was performed. The patient has been free of recurrence for 3 years without radiotherapy. Chondroblastoma of the temporal bone is widely accepted as a benign tumor and regrowth after gross total removal is very rare. However, some cases of chondroblastoma have potentially high mitotic activity.  (+info)

Skull base chondroblastoma: a case report. (8/41)

Chondroblastoma is a rare tumor of the skull. Temporal bone is the commonest site of involvement in the skull. We present a thirty one year old man who presented with painless swelling over the left temporal bone, which was near totally excised after preoperative embolization. Management of this unusual tumor and its complications are discussed.  (+info)

The tumor usually appears as a well-defined lump or mass that is surrounded by a fibrous capsule. The surface of the tumor may be smooth or rough, and it may be covered with cartilage or bone. Chondroblastoma tends to grow slowly over time, but it can sometimes become malignant and invade surrounding tissues.

Chondroblastoma is most commonly found in young adults, typically between the ages of 20 and 40. The exact cause of chondroblastoma is not known, but it may be linked to genetic factors or environmental exposures. Treatment usually involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to prevent recurrence.

Some of the common symptoms of Chondroblastoma include:

* Painless lump or mass in the affected limb
* Limited mobility and stiffness in the affected joint
* Swelling and redness in the affected area
* Warmth and tenderness to touch

Some of the common diagnostic tests for Chondroblastoma include:

* X-rays
* CT scans
* MRI scans
* Biopsy

It's important to note that while chondroblastoma is a benign tumor, it can recur in some cases. Therefore, regular follow-up appointments with your doctor are essential to monitor the condition and detect any signs of recurrence early on.

Surgery is often necessary to treat bone cysts, aneurysmal, and the type of surgery will depend on the size and location of the cyst. The goal of surgery is to remove the cyst and any associated damage to the bone. In some cases, the bone may need to be repaired or replaced with a prosthetic.

Bone cysts, aneurysmal are relatively rare and account for only about 1% of all bone tumors. They can occur in people of any age but are most commonly seen in children and young adults. Treatment is usually successful, but there is a risk of complications such as infection or nerve damage.

Bone cysts, aneurysmal are also known as bone aneurysmal cysts or BACs. They are different from other types of bone cysts, such as simple bone cysts or fibrous dysplasia, which have a different cause and may require different treatment.

Overall, the prognosis for bone cysts, aneurysmal is generally good if they are treated promptly and effectively. However, there is always a risk of complications, and ongoing follow-up with a healthcare provider is important to monitor for any signs of recurrence or further problems.

Some common types of bone neoplasms include:

* Osteochondromas: These are benign tumors that grow on the surface of a bone.
* Giant cell tumors: These are benign tumors that can occur in any bone of the body.
* Chondromyxoid fibromas: These are rare, benign tumors that develop in the cartilage of a bone.
* Ewing's sarcoma: This is a malignant tumor that usually occurs in the long bones of the arms and legs.
* Multiple myeloma: This is a type of cancer that affects the plasma cells in the bone marrow.

Symptoms of bone neoplasms can include pain, swelling, or deformity of the affected bone, as well as weakness or fatigue. Treatment options depend on the type and location of the tumor, as well as the severity of the symptoms. Treatment may involve surgery, radiation therapy, chemotherapy, or a combination of these.

Femoral neoplasms refer to abnormal growths or tumors that occur in the femur, which is the longest bone in the human body and runs from the hip joint to the knee joint. These tumors can be benign (non-cancerous) or malignant (cancerous), and their impact on the affected individual can range from minimal to severe.

Types of Femoral Neoplasms:

There are several types of femoral neoplasms, including:

1. Osteosarcoma: This is a type of primary bone cancer that originates in the femur. It is rare and tends to affect children and young adults.
2. Chondrosarcoma: This is another type of primary bone cancer that arises in the cartilage cells of the femur. It is more common than osteosarcoma and affects mostly older adults.
3. Ewing's Sarcoma: This is a rare type of bone cancer that can occur in any bone, including the femur. It typically affects children and young adults.
4. Giant Cell Tumor: This is a benign tumor that occurs in the bones, including the femur. While it is not cancerous, it can cause significant symptoms and may require surgical treatment.

Symptoms of Femoral Neoplasms:

The symptoms of femoral neoplasms can vary depending on the type and location of the tumor. Common symptoms include:

1. Pain: Patients with femoral neoplasms may experience pain in the affected leg, which can be worse with activity or weight-bearing.
2. Swelling: The affected limb may become swollen due to fluid accumulation or the growth of the tumor.
3. Limited mobility: Patients may experience limited mobility or stiffness in the affected joint due to pain or swelling.
4. Fracture: In some cases, femoral neoplasms can cause a fracture or weakening of the bone, which can lead to further complications.

Diagnosis and Treatment of Femoral Neoplasms:

The diagnosis of femoral neoplasms typically involves a combination of imaging studies and biopsy. Imaging studies, such as X-rays, CT scans, or MRI scans, can help identify the location and extent of the tumor. A biopsy may be performed to confirm the diagnosis and determine the type of tumor.

Treatment for femoral neoplasms depends on the type and location of the tumor, as well as the patient's age and overall health. Treatment options may include:

1. Observation: Small, benign tumors may not require immediate treatment and can be monitored with regular imaging studies to ensure that they do not grow or change over time.
2. Surgery: Many femoral neoplasms can be treated with surgery to remove the tumor and any affected bone tissue. In some cases, this may involve removing a portion of the femur or replacing it with a prosthetic implant.
3. Radiation therapy: This may be used in combination with surgery to treat more aggressive tumors or those that have spread to other areas of the body.
4. Chemotherapy: This may also be used in combination with surgery and radiation therapy to treat more aggressive tumors or those that have spread to other areas of the body.
5. Targeted therapy: This is a type of chemotherapy that targets specific molecules involved in the growth and progression of the tumor. Examples include denintuzumab mafodotin, which targets a protein called B-cell CD19, and olaratumab, which targets a protein called platelet-derived growth factor receptor alpha (PDGFR-alpha).
6. Immunotherapy: This is a type of treatment that uses the body's own immune system to fight cancer. Examples include pembrolizumab and nivolumab, which are checkpoint inhibitors that work by blocking proteins on T cells that prevent them from attacking cancer cells.

The prognosis for patients with femoral neoplasms depends on the type and location of the tumor, as well as the patient's age and overall health. In general, the prognosis is better for patients with benign tumors than those with malignant ones. However, even for patients with malignant tumors, there are many treatment options available, and the prognosis can vary depending on the specifics of the case.

It's important to note that these are general treatment options and the best course of treatment will depend on the specifics of each individual case. Patients should discuss their diagnosis and treatment options with their healthcare provider to determine the most appropriate course of action for their specific situation.

Examples of Skull Neoplasms include:

1. Meningioma: A benign tumor that arises from the meninges, the protective covering of the brain and spinal cord.
2. Acoustic neuroma: A benign tumor that grows on the nerve that connects the inner ear to the brain.
3. Pineal parenchymal tumors: Tumors that arise in the pineal gland, a small endocrine gland located in the brain.
4. Craniopharyngiomas: Benign tumors that arise near the pituitary gland, which regulates hormone production.
5. Medulloblastoma: A malignant tumor that arises in the cerebellum, a part of the brain that controls movement and coordination.
6. Germ cell tumors: Tumors that arise from immature cells that form in the embryo. These can be benign or malignant.
7. PNETs (primitive neuroectodermal tumors): Malignant tumors that arise from early forms of nerve cells.
8. Astrocytomas: Tumors that arise from the supportive tissue of the brain called astrocytes. These can be benign or malignant.
9. Oligodendrogliomas: Tumors that arise from the supportive tissue of the brain called oligodendrocytes. These can be benign or malignant.
10. Melanotic neuroectodermal tumors: Rare, malignant tumors that contain pigmented cells.

The hallmark of GCTB is its large size, with tumors often measuring several centimeters in diameter. The tumor cells are giant cells, which are larger than normal osteoblasts, and they have a distinctive "salt and pepper" appearance under the microscope due to the mixture of light and dark-staining cytoplasmic granules.

The clinical presentation of GCTB varies depending on the location and size of the tumor. Large tumors can cause symptoms such as pain, swelling, and limited mobility in the affected limb. Smaller tumors may not cause any symptoms and may be incidentally discovered on imaging studies performed for other reasons.

GCTB is a slow-growing tumor, and the exact cause of its development is unknown. Genetic mutations have been identified in some cases, but the exact mechanisms underlying GCTB remain unclear. Treatment options for GCTB include surgery, radiation therapy, and chemotherapy, depending on the size and location of the tumor and the patient's overall health.

In conclusion, giant cell tumor of bone is a rare and benign bone tumor that can occur in any bone of the body. It is characterized by its large size and distinctive histopathological features. Treatment options vary depending on the size and location of the tumor and the patient's overall health.

Damron, Timothy A. "Chondroblastoma." MedScape (2014). Web. 6 Dec. 2015 Turcotte, Robert E., et al. "Chondroblastoma." Human ... There is no indication of a racial predilection for chondroblastoma. The etiology of chondroblastoma is uncertain, as there is ... have better prognoses than patients with atypical chondroblastoma (flat bones, skull, etc.). Chondroblastoma was first ... Chondroblastoma shows a predilection towards the male sex, with a ratio of male to female patients of 2:1. The most commonly ...
Khalil, G E W (1980). "Benign chondroblastoma. A case report and review of the literature". Le Journal Médical Libanais. 31 (1 ...
Epiphyseal lesions include chondroblastoma and giant-cell tumor. Long bone Longitudinal section of head of left humerus. ...
Somatic mutations mostly in the H3F3B gene are associated with chondroblastoma, but some are associated with mutations in H3F3A ... "Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone". Nature Genetics. 45 (12): 1479- ...
Mutations in H3F3A and H3F3B are also found in chondroblastoma and giant cell tumor of bone. GRCh38: Ensembl release 89: ... December 2013). "Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone". Nature ...
An aneurysmal bone cyst can arise from a pre-existing chondroblastoma, a chondromyxoid fibroma, an osteoblastoma, a giant cell ...
... chondroblastoma is composed of cells resembling the precursor of chondrocytes. Many types of blastoma have been linked to a ...
These include, aneurysmal bone cyst, chondroblastoma, simple bone cyst, osteoid osteoma, osteoblastoma, osteosarcoma, giant- ...
... insufficiency Cholesterol ester storage disease Cholesterol esterification disorder Cholesterol pneumonia Chondroblastoma ...
... chondroblastoma MeSH C04.557.450.565.265 - chondroma MeSH C04.557.450.565.265.270 - chondromatosis MeSH C04.557.450.565.280 - ...
NOS Chondromatous giant cell tumor Codman tumor M9230/3 Chondroblastoma, malignant M9231/3 Myxoid chondrosarcoma M9240/3 ... chondroma Periosteal chondroma M9221/3 Juxtacortical chondrosarcoma Periosteal chondrosarcoma M9230/0 Chondroblastoma, ...
Chondroblastoma - Chondrocyte - Chondrogenesis - Chondromalacia patellae - Chondromyxoid fibroma - Chondrosarcoma - Chopart's ...
Chondroblastomas account for less than 2% of all bone tumors, and metaphyseal or diaphyseal chondroblastoma occurs in only 2% ... A chondroblastoma is a rare benign cartilaginous neoplasm that characteristically arises in the epiphysis of a long bone in ... Chondroblastoma-like osteosarcoma is a very rare subtype of osteoscarcoma that may be confused with chondroblastoma. [18] ... encoded search term (Chondroblastoma Imaging and Diagnosis) and Chondroblastoma Imaging and Diagnosis What to Read Next on ...
... J Am Podiatry Assoc. 1975 Feb;65(2):184-7. doi: 10.7547/87507315-65-2-184. ...
... chondroblastoma-like osteosarcoma should be considered in the differential diagnosis of chondroblastoma, especially in the ... Chondroblastoma-like Osteosarcoma Youssef Al Hmada 1 , Anas Bernieh 1 , Robert W Morris 1 , Jack Lewin 1 , Timothy Allen 1 ... Chondroblastoma-like Osteosarcoma Youssef Al Hmada et al. Arch Pathol Lab Med. 2020 Jan. ... Chondroblastoma: An Update. Chen W, DiFrancesco LM. Chen W, et al. Arch Pathol Lab Med. 2017 Jun;141(6):867-871. doi: 10.5858/ ...
Copyright © 2023 BMJ Publishing Group Ltd & Association of Clinical Pathologists. All rights reserved.. ...
Resources on Chondroblastoma and related topics in OrthopaedicsOne spaces. Page: Chondroblastoma (OrthopaedicsOne Articles) ... Chondroblastoma of bone: long-term results and functional outcome after intralesional curettage.J Bone Joint Surg Br. 2005 Jul; ... Chondroblastoma. OrthopaedicsOne Articles. In: OrthopaedicsOne - The Orthopaedic Knowledge Network. Created Mar 21, 2008 10:30 ... benign bone_lesion bone_tumor chondroblastoma musculoskeletal_tumor tumor 4255 days ago. ...
A massive chondroblastoma in the proximal humerus simulating malignant bone tumors. A massive chondroblastoma in the proximal ... Chondroblastoma is a mostly benign bone neoplasm that typically affects the second decade of life and exhibits a lytic lesion ... We report an extreme case of massive, destructive chondroblastoma of the proximal humerus in a 9-year-old girl. It was ... The present case demonstrates clinical and radiological differentiations of the massive chondroblastoma from the other lesions ...
... Academic Article * ... Pathology was typical for chondroblastoma: a rare, benign but locally invasive chondroid tumor. Genetic testing revealed a ...
OR chondroblastoma [tw]. OR chondroblastomas [tw]. OR chondroma [tw]. OR chondromas [tw]. OR chondrosarcoma [tw]. OR ...
Chondroblastoma (American Academy of Orthopaedic Surgeons) * Chondromyxoid Fibroma (American Academy of Orthopaedic Surgeons) ...
Knee effusions may be the result of trauma, overuse or systemic disease. An understanding of knee pathoanatomy is an invaluable part of making the correct diagnosis and formulating a treatment plan. Taking a thorough medical history is the key component of the evaluation. The most common traumatic causes of knee effusion are ligamentous, osseous and meniscal injuries, and overuse syndromes. Atraumatic etiologies include arthritis, infection, crystal deposition and tumor. It is essential to compare the affected knee with the unaffected knee. Systematic physical examination of the knee, using specific maneuvers, and the appropriate use of diagnostic imaging studies and arthrocentesis establish the correct diagnosis and treatment.
Chondroblastoma.. Ecklund K; Jaramillo D; Buonomo C. Radiographics; 1996 Jul; 16(4):979-82. PubMed ID: 8835989. [No Abstract] [ ...
Chondroblastoma / genetics* Actions. * Search in PubMed * Search in MeSH * Add to Search ...
Malignant Chondroblastoma,o,1404,,1,0,1,,, 2393,10439,Chondroblastoma,y,1861,,1,0,1,,, 2394,29966,Work Injury Industrial- ...
2. Expression of collagen type II, S100B, S100A2 and osteocalcin in chondroblastoma and chondromyxoid fibroma.. Park HR; Park ... 3. The role of noncartilage-specific molecules in differentiation of cartilaginous tumors: lessons from chondroblastoma and ... 8. Chondroblastomas but not chondromyxoid fibromas express cytokeratins: an unusual presentation of a chondroblastoma in the ... Electron microscopic and immunohistochemical studies on chondroblastoma].. Morimoto K; Okada S. Nihon Seikeigeka Gakkai Zasshi ...
Arthroscopic Management of Juxta-articular Proximal Humeral Chondroblastoma: The Bazooka Technique. Mohamed Gamal Morsy, Hesham ...
Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately. Chondroblastoma is a rare benign ... Chondroblastoma is normally a uncommon benign bone tumor comprising around 1% of the complete bone tumors developing in the ... Chondroblastoma could possibly be developed in virtually any ages, nevertheless, it really is prevalent in kids and youthful ... Conversation Chondroblastoma is definitely a rare benign cartilaginous bone tumor consisting of 1% of the complete bone tumors ...
Chondroblastoma with secondary aneurysmal bone cyst of the hamate: case report. J Hand Surg Am. 2012 Mar; 37: (3)538-42. View ...
Chondroblastoma, NOS (C40._, C41._). 9230/3. Chondroblastoma, malignant (C40._, C41._). 9231/3. Myxoid chondrosarcoma. ...
Chondroblastoma: 62% (Hum Pathol 2013;44:237) *Chordoma: 100% (conventional chordoma), 94% (chondroid chordoma), 100% (poorly ...
Chondroblastoma, although rare in some studies, accounted for 10% of the benign skull tumors in the Mayo series. ... Konishi E, Okubo T, Itoi M, Katsumi Y, Murata H, Yanagisawa A. Chondroblastoma of trapezium with metacarpal involvement. ...
Benign bone tumors such as osteoid osteoma, osteochondroma, chondroblastoma, and bone cysts ...
Curettage for benign bone tumours (Giant cell tumours, chondroblastoma, osteoblastomaetc). *Non-surgical management like ...
Chondroblastoma Preferred Term Term UI T008174. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1966). ... Chondroblastoma Preferred Concept UI. M0004304. Scope Note. A usually benign tumor composed of cells which arise from ... Chondroblastoma. Tree Number(s). C04.557.450.565.250. Unique ID. D002804. RDF Unique Identifier. http://id.nlm.nih.gov/mesh/ ...
Osteocartilaginous melanoma is a rare variant of malignant melanoma that needs to be differentiated from chondroblastoma and ... Pathologic evaluation of the excisional biopsy revealed diffuse epithelioid and chondroblastoma-like melanocytes with atypia ...
Malignant C2945 Chondroblastoma Chondroblastoma, NOS ,, Chondroblastoma, Not Otherwise Specified A benign, chondroid-producing ...
Mutation analysis of H3F3A and H3F3B as a diagnostic tool for giant cell tumor of bone and chondroblastoma. Am J Surg Pathol. ...
Chondroblastoma. Condition Chondroblastomas occur when chondroblasts grow out of control and cause a benign (non-cancerous) ...
Chondroblastoma Preferred Term Term UI T008174. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1966). ... Chondroblastoma Preferred Concept UI. M0004304. Scope Note. A usually benign tumor composed of cells which arise from ... Chondroblastoma. Tree Number(s). C04.557.450.565.250. Unique ID. D002804. RDF Unique Identifier. http://id.nlm.nih.gov/mesh/ ...
The common tumours are benign and include Giant cell tumour and Chondroblastoma. Secondary metastases and Osteosarcoma are the ... The most common tumours included giant cell tumour and chondroblastoma, the majority of the malignant lesions included ...
4. A chondroblastoma. giant cell tumor of bone. giant cell tumor of bone. giant cell tumor of bone ...
  • If the chondroblastoma crosses the physis, it may be mistaken for either a chondromyxoid fibroma or a giant cell tumor (which typically occurs in a slightly older patient population, generally has no mineralization, and usually has nonsclerotic borders). (medscape.com)
  • Pathology was typical for chondroblastoma: a rare, benign but locally invasive chondroid tumor. (unm.edu)
  • Chondroblastoma is normally a uncommon benign bone tumor comprising around 1% of the complete bone tumors developing in the epiphysis of lengthy bones. (columbiagypsy.net)
  • Conversation Chondroblastoma is definitely a rare benign cartilaginous bone tumor consisting of 1% of the complete bone tumors, and the common onset age group is 10~20 years. (columbiagypsy.net)
  • This includes primary bone and soft tissue sarcomas, locally active conditions such as giant cell tumor, aneurysmal bone cyst, and chondroblastoma, as well as impending and pathologic fractures from metastatic carcinoma, multiple myeloma, and lymphoma. (stanford.edu)
  • Tumor generalmente benigno que consiste en células que provienen de condroblastos o de sus precursores y que tienden a diferenciarse en células de cartílago. (bvsalud.org)
  • A case of chondroblastoma, which is a benign tumor of the bone, with distant metastases to the lung and abdominal wall is reported. (who.int)
  • Chondroblastoma-like osteosarcoma is a very rare subtype of osteoscarcoma that may be confused with chondroblastoma. (medscape.com)
  • Chondroblastoma-like osteosarcoma is an exceedingly rare variant of osteosarcoma, with 22 cases reported in the English-language literature. (nih.gov)
  • Histologically, chondroblastoma-like osteosarcoma is characterized by monotonous, minimally to moderately atypical rounded cells with ovoid nuclei resembling chondroblastoma, and abnormal osteoid deposition with destruction of the bone. (nih.gov)
  • To review the clinical, radiographic, and histopathologic features of chondroblastoma-like osteosarcoma. (nih.gov)
  • PubMed-published chondroblastoma-like osteosarcoma cases in the English-language literature. (nih.gov)
  • Although exceedingly rare, chondroblastoma-like osteosarcoma should be considered in the differential diagnosis of chondroblastoma, especially in the presence of radiologic findings suggestive of an aggressive lesion. (nih.gov)
  • The most common tumours included giant cell tumour and chondroblastoma, the majority of the malignant lesions included secondary metastasis and osteosarcoma. (jortho.org)
  • Atypical', 'aggressive' or 'malignant' chondroblastoma? (bmj.com)
  • A massive chondroblastoma in the proximal humerus simulating malignant bone tumors. (bvsalud.org)
  • Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately 1% of most bone tumors and characteristically arises in the epiphysis of an extended bone, specially the humerus, tibia, and femur. (columbiagypsy.net)
  • Confusion may arise if the chondroblastoma extends across the physis and mimics a metaphyseal lesion or if it arises in an atypical location such as the pelvis. (medscape.com)
  • Chondroblastoma of the temporal bone typically occurs in older males (30-40 yr), and patients with tumors that arise from the epiphyseal cartilage of the long bones are generally between 20 and 30 years of age. (medscape.com)
  • 3. The role of noncartilage-specific molecules in differentiation of cartilaginous tumors: lessons from chondroblastoma and chondromyxoid fibroma. (nih.gov)
  • Chondroblastoma, although rare in some studies, accounted for 10% of the benign skull tumors in the Mayo series. (medscape.com)
  • Chondroblastoma Click below for a list of tumors with coffee bean nuclei. (pathologymcq.com)
  • 1. Immunohistochemical analysis for Sox9 reveals the cartilaginous character of chondroblastoma and chondromyxoid fibroma of the bone. (nih.gov)
  • 2. Expression of collagen type II, S100B, S100A2 and osteocalcin in chondroblastoma and chondromyxoid fibroma. (nih.gov)
  • With reference to the histogenesis of chondroblastoma, chondromyxoid fibroma and mesenchymal chondrosarcoma. (nih.gov)
  • Chondroblastoma is a mostly benign bone neoplasm that typically affects the second decade of life and exhibits a lytic lesion in the epiphysis of long bones . (bvsalud.org)
  • Although a chondroblastoma has nonspecific findings, if any, at physical examination, the imaging findings of chondroblastomas are often straightforward when a nonaggressive epiphyseal lesion is identified in a child or adolescent patient. (medscape.com)
  • 8. Chondroblastomas but not chondromyxoid fibromas express cytokeratins: an unusual presentation of a chondroblastoma in the metaphyseal cortex of the tibia. (nih.gov)
  • The common tumours are benign and include Giant cell tumour and Chondroblastoma. (jortho.org)
  • Metastatic chondroblastoma. (who.int)
  • This image shows a chondroblastoma with a characteristically lucent lesion and well-defined margins. (medscape.com)
  • The present case demonstrates clinical and radiological differentiations of the massive chondroblastoma from the other lesions and histopathological understandings for this lesion. (bvsalud.org)
  • Histopathological examination from biopsy proved chondroblastoma . (bvsalud.org)
  • Afterward, total laminectomy of L4, the primary site, was performed, the patient recovered after the surgical treatment, and transferred to the division of thoracic surgical treatment for pulmonary biopsy, and by carrying out wedge resection applying Video-Assisted Thoracic Surgical treatment, biopsy results fitting with chondroblastoma identical to the primary site were acquired. (columbiagypsy.net)
  • From time to time, chondroblastoma invades the articular cavity, and even though very uncommon, it might take invasive classes such as for example metastasis (2). (columbiagypsy.net)
  • A chondroblastoma is a rare benign cartilaginous neoplasm that characteristically arises in the epiphysis of a long bone in young patients. (medscape.com)
  • Chondroblastoma is normally produced by chodroblast that's primitive cellular material of the epiphyseal cartilaginous lamina, and due to it, it really is developed often in the epiphysis of lengthy bones, and even though rare, it really is created in little tubular bone of higher and lower extremities in some instances ADAM8 (11,12). (columbiagypsy.net)
  • Angiography may be used to create a vascular road map of the chondroblastoma for surgical planning, but the angiograms usually show no vascular abnormality. (medscape.com)
  • The vertebra is an extremely rare main site of chondroblastoma, and only less than 10 instances have been reported in literatures (8-10). (columbiagypsy.net)
  • We report an extreme case of massive, destructive chondroblastoma of the proximal humerus in a 9-year-old girl . (bvsalud.org)
  • Chondroblastoma could possibly be developed in virtually any ages, nevertheless, it really is prevalent in kids and youthful adolescent between your age of 10 and twenty years, and it takes place more often in the male compared to the female (1). (columbiagypsy.net)
  • Suneja R, Grimer RJ, Belthur M, Jeys L, Carter SR, Tillman RM, Davies AM. Chondroblastoma of bone: long-term results and functional outcome after intralesional curettage.J Bone Joint Surg Br. (orthopaedicsone.com)
  • In histological exam, both main site and the metastasized site showed the typical chondroblastoma pattern. (columbiagypsy.net)
  • 11. [Electron microscopic and immunohistochemical studies on chondroblastoma]. (nih.gov)
  • The following 4 images are from the same patient with chondroblastoma . (medscape.com)
  • Chondroblastoma of bone in a pediatric population. (medscape.com)
  • [ 5 ] On examination of about 15 examples of GCTTS and PVNS, large areas of chondroid differentiation were noted that could not be distinguished from chondroblastoma of bone by either histologic or electron microscopic features. (medscape.com)
  • The researchers theorized that chondroblastoma of bone stems from an intraosseous proliferation of tendon sheath cells that have a predilection for chondroid formation. (medscape.com)
  • In the United States, chondroblastoma accounts for approximately 1% of all bone tumors. (medscape.com)
  • 2. Proximal Tibia Chondroblastoma Treated With Curettage and Bone Graft and Cement Use. (nih.gov)
  • 5. Chondroblastoma in the long bone diaphysis: a report of two cases with literature review. (nih.gov)
  • 8. Chondroblastoma of bone: long-term results and functional outcome after intralesional curettage. (nih.gov)
  • 10. Distal Tibial Chondroblastoma With Intra-articular Penetration Treated With Gelatin Foam Sponge and Bone Grafting. (nih.gov)
  • 12. Pure reconstruction with bone substitute pellets graft following curettage and high-speed burring for chondroblastoma of the proximal tibia: a case report and review of the literature. (nih.gov)
  • 14. Combined Autograft and Bone Cement for Painful Chondroblastoma: A Case Report. (nih.gov)
  • 17. Vascularized Bone Autograft for the Treatment of Chondroblastoma of the Talus at Imminent Risk of Joint Breakdown: Three Case Reports. (nih.gov)
  • Patients with benign chondroblastoma may limit activities because of pain. (medscape.com)
  • 20. [Treatment of benign chondroblastoma]. (nih.gov)
  • Although an epiphyseal or apophyseal location is classic for chondroblastoma and extension into the metaphysis may be seen, purely metaphyseal or diaphyseal chondroblastomas have been reported. (medscape.com)
  • Chondroblastoma is an osteoid-forming, but not cartilage-forming neoplasm. (medscape.com)
  • 6. Clinical and radiological long-term results after operative treatment of chondroblastoma. (nih.gov)
  • 3. [Clinical observation of expanded curettage in treatment of chondroblastoma]. (nih.gov)
  • On histologic examination, giant cell tumors have elongated cells that are clustered together, in contrast to the round or polygonal cells of chondroblastoma. (medscape.com)
  • Risk factors for chondroblastoma remain to be fully defined. (medscape.com)
  • 18. Capitate Chondroblastoma: A Case Report and Review of the Literature. (nih.gov)
  • 1. The diagnosis and treatment of tibial intercondylar chondroblastoma. (nih.gov)
  • 15. Functional and Oncological Outcome After Treatment of Chondroblastoma With Intralesional Curettage. (nih.gov)