A strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium Cl(-) anion.
Flammable, amorphous, vegetable products of secretion or disintegration, usually formed in special cavities of plants. They are generally insoluble in water and soluble in alcohol, carbon tetrachloride, ether, or volatile oils. They are fusible and have a conchoidal fracture. They are the oxidation or polymerization products of the terpenes, and are mixtures of aromatic acids and esters. Most are soft and sticky, but harden after exposure to cold. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)
Synthetic resins, containing an inert filler, that are widely used in dentistry.
High-molecular-weight insoluble polymers that contain functional cationic groups capable of undergoing exchange reactions with anions.
Polymers of high molecular weight which at some stage are capable of being molded and then harden to form useful components.
High molecular weight, insoluble polymers which contain functional groups that are capable of undergoing exchange reactions (ION EXCHANGE) with either cations or anions.
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA.
Agents that promote the excretion of urine through their effects on kidney function.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.
Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.
Use of written, printed, or graphic materials upon or accompanying a product or its container or wrapper. It includes purpose, effect, description, directions, hazards, warnings, and other relevant information.
The action of a drug that may affect the activity, metabolism, or toxicity of another drug.
Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
Form in which product is processed or wrapped and labeled. PRODUCT LABELING is also available.
The number of copies of a given gene present in the cell of an organism. An increase in gene dosage (by GENE DUPLICATION for example) can result in higher levels of gene product formation. GENE DOSAGE COMPENSATION mechanisms result in adjustments to the level GENE EXPRESSION when there are changes or differences in gene dosage.
Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing genes that lie on the SEX CHROMOSOMES. Because the sex chromosomes are only partially homologous, there is a different copy number, i.e., dosage, of these genes in males vs. females. In DROSOPHILA, dosage compensation is accomplished by hypertranscription of genes located on the X CHROMOSOME. In mammals, dosage compensation of X chromosome genes is accomplished by random X CHROMOSOME INACTIVATION of one of the two X chromosomes in the female.
Errors in prescribing, dispensing, or administering medication with the result that the patient fails to receive the correct drug or the indicated proper drug dosage.
A five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.
Exclusive legal rights or privileges applied to inventions, plants, etc.
Hydrocarbon-rich byproducts from the non-fossilized BIOMASS that are combusted to generate energy as opposed to fossilized hydrocarbon deposits (FOSSIL FUELS).
The relative amounts of various components in the body, such as percentage of body fat.
Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)
Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance.
NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.
It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)
Patient health knowledge related to medications including what is being used and why as well as instructions and precautions.
Services providing pharmaceutic and therapeutic drug information and consultation.
Societies whose membership is limited to pharmacists.
Advanced programs of training to meet certain professional requirements in fields other than medicine or dentistry, e.g., pharmacology, nutrition, nursing, etc.
Fats containing one or more double bonds, as from oleic acid, an unsaturated fatty acid.
Specific practices for the prevention of disease or mental disorders in susceptible individuals or populations. These include HEALTH PROMOTION, including mental health; protective procedures, such as COMMUNICABLE DISEASE CONTROL; and monitoring and regulation of ENVIRONMENTAL POLLUTANTS. Primary prevention is to be distinguished from SECONDARY PREVENTION and TERTIARY PREVENTION.
A corneal disease in which there is a deposition of phospholipid and cholesterol in the corneal stroma and anterior sclera.
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Cholesterol which is contained in or bound to low density lipoproteins (LDL), including CHOLESTEROL ESTERS and free cholesterol.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL ESTERS and free cholesterol.
Financing of medical care provided to public assistance recipients.
Medical services for which no payment is received. Uncompensated care includes charity care and bad debts.
The state or quality of being kind, charitable, or beneficial. (from American Heritage Dictionary of the English Language, 4th ed). The ethical principle of BENEFICENCE requires producing net benefit over harm. (Bioethics Thesaurus)
Non-profit organizations concerned with various aspects of health, e.g., education, promotion, treatment, services, etc.

The pharmacoeconomic benefits of cholesterol reduction. (1/330)

Recent studies show that cholesterol-lowering therapy can reduce morbidity and mortality in hypercholesterolemic patients without preexisting coronary heart disease (primary prevention) and with coronary heart disease (secondary prevention). The high cost of treatment per event prevented, especially for primary prevention, raises concerns about widespread use of cholesterol-lowering therapy. Does cholesterol reduction reduce utilization of healthcare resources, and can society afford to pay for reducing cholesterol in all patients with hypercholesterolemia, irrespective of risk factors? Is cost-effectiveness of therapy affected by differing cholesterol levels, age of the patients, the duration of therapy, or the presence of risk factors? Current pharmacoeconomic studies support the use of the statins for secondary prevention, and primary prevention in high-risk patients, and provide key information for policy decision making in the treatment of patients with hypercholesterolemia.  (+info)

Antilithiasic effect of beta-cyclodextrin in LPN hamster: comparison with cholestyramine. (2/330)

Beta-Cyclodextrin (BCD), a cyclic oligosaccharide that binds cholesterol and bile acids in vitro, has been previously shown to be an effective plasma cholesterol lowering agent in hamsters and domestic pigs. This study examined the effects of BCD as compared with cholestyramine on cholesterol and bile acid metabolism in the LPN hamster model model for cholesterol gallstones. The incidence of cholesterol gallstones was 65% in LPN hamsters fed the lithogenic diet, but decreased linearly with increasing amounts of BCD in the diet to be nil at a dose of 10% BCD. In gallbladder bile, cholesterol, phospholipid and chenodeoxycholate concentrations, hydrophobic and lithogenic indices were all significantly decreased by 10% BCD. Increases in bile acid synthesis (+110%), sterol 27-hydroxylase activity (+106%), and biliary cholate secretion (+140%) were also observed, whereas the biliary secretion of chenodeoxycholate decreased (-43%). The fecal output of chenodeoxycholate and cholate (plus derivatives) was increased by +147 and +64%, respectively, suggesting that BCD reduced the chenodeoxycholate intestinal absorption preferentially. Dietary cholestyramine decreased biliary bile acid concentration and secretion, but dramatically increased the fecal excretion of chenodeoxycholate and cholate plus their derivatives (+328 and +1940%, respectively). In contrast to BCD, the resin increased the lithogenic index in bile, induced black gallstones in 34% of hamsters, and stimulated markedly the activities of HMG-CoA reductase (+670%), sterol 27-hydroxylase (+310%), and cholesterol 7alpha-hydroxylase (+390%). Thus, beta-cyclodextrin (BCD) prevented cholesterol gallstone formation by decreasing specifically the reabsorption of chenodeoxycholate, stimulating its biosynthesis and favoring its fecal elimination. BCD had a milder effect on lipid metabolism than cholestyramine and does not predispose animals to black gallstones as cholestyramine does in this animal model.  (+info)

Increased fecal bile acid excretion and changes in the circulating bile acid pool are involved in the hypocholesterolemic and gallstone-preventive actions of psyllium in hamsters. (3/330)

The lipid-lowering effect of psyllium (PSY) is well established. Enhanced fecal bile acid excretion and a stimulation of hepatic bile acid synthesis are discussed as primary mechanisms of this action. To further examine the effect of bile acid excretion and specifically of compositional alterations in the bile acid pool on the cholesterol-lowering and gallstone-preventing action of PSY, male golden Syrian hamsters were fed lithogenic diets containing 5 g/100 g fat, 0.4 g/100 g cholesterol and 0 (control), 4 or 6% PSY or 1% cholestyramine (CHY). PSY significantly lowered plasma total cholesterol and triacylglycerol at a magnitude comparable to that induced by CHY. Although hepatic cholesteryl ester accumulation was completely inhibited by CHY, PSY did not prevent the hepatic storage of esterified cholesterol. PSY and CHY caused distinct alterations in the bile acid profile. PSY caused a selective reduction of taurine-conjugated bile acids, especially of taurochenodeoxycholate. As a result, the glycine:taurine conjugation and the cholate:chenodeoxycholate ratios were significantly higher in PSY-fed hamsters. PSY and CHY normalized the lithogenic index and prevented cholesterol gallstone formation compared with controls. Daily fecal bile acid excretion was approximately 400% greater in hamsters fed 6% PSY, whereas CHY caused an 11-fold increase. Daily neutral sterol excretion did not differ in PSY-fed hamsters but was >100% greater in those fed CHY than in controls. These data emphasize the potent lipid-lowering effect of PSY. Increased fecal bile acid excretion and alterations of the circulating bile acid pool by removal of dihydroxy bile acids (e.g., taurochenodeoxycholate) appear to be main modulators of the hypocholesterolemic action of PSY by leading to an up-regulation of hepatic bile acid synthesis.  (+info)

Secondary prevention with lipid lowering therapy in familial hypercholesterolemia: a correlation between new evolution of stenotic lesion and achieved cholesterol levels after revascularization procedures. (4/330)

OBJECT: To assess the value of secondary prevention with lipid lowering therapy following either balloon angioplasty (PTCA) or bypass surgery (CABG) in familial hypercholesterolemia patients, the correlation of the new evolution of stenotic lesions and therapeutically achieved cholesterol levels was studied in 50 patients. METHODS: All surviving patients were followed angiographically after 5 years, and findings were correlated with the annually determined total serum cholesterol (TC) levels. RESULTS: New coronary atherosclerotic plaques were not observed in 18 patients in whom the TC was controlled to <220 mg/dl but in 19 of 32 patients in whom the TC was >220 mg/dl, a new evolution of stenotic lesions was observed angiographically. CONCLUSION: The new evolution of stenotic lesions following revascularization in patients with FH can be controlled significantly by lipid lowering therapy to maintain a TC level of <220 mg/dl, and if diet alone can not achieve it, aggressive medication and even LDL apheresis might be justified.  (+info)

Structure, evolution, and liver-specific expression of sterol 12alpha-hydroxylase P450 (CYP8B). (5/330)

The rat CYP8B cDNA encoding sterol 12alpha-hydroxylase was cloned and sequenced. The amino acid sequence of the heme-binding region of CYP8B was close to those of CYP7A (cholesterol 7alpha-hydroxylase) and CYP7B (oxysterol 7alpha-hydroxylase). Molecular phylogenetic analysis suggests that CYP8B and the CYP7 family derive from a common ancestor. The P450s of the CYP7 and CYP8 families, except for CYP8A (prostacyclin synthase), catalyze the oxygenation of sterols from an alpha surface in the middle of the steroid skeleton. These facts suggest that CYP8B is a P450 closely linked to those of the CYP7 family. CYP8B was expressed specifically in liver. Hepatic CYP8B mRNA level and the 12alpha-hydroxylase activity were altered by cholestyramine feeding, starvation, streptozotocin-induced diabetes mellitus, and administration of clofibrate, dexamethasone or thyroxin, indicating the pretranslational regulation of CYP8B expression. The enhanced CYP8B mRNA expression in streptozotocin-induced diabetic rats was significantly decreased by insulin within 3 h of its administration. These facts demonstrate a regulatory role of insulin in CYP8B expression as a suppressor.  (+info)

Aberrant oxidation of the cholesterol side chain in bile acid synthesis of sterol carrier protein-2/sterol carrier protein-x knockout mice. (6/330)

Peroxisomal beta-oxidation plays an important role in the metabolism of a wide range of substrates, including various fatty acids and the steroid side chain in bile acid synthesis. Two distinct thiolases have been implicated to function in peroxisomal beta-oxidation: the long known 41-kDa beta-ketothiolase identified by Hashimoto and co-workers (Hijikata, M., Ishii, N., Kagamiyama, H., Osumi, T., and Hashimoto, T. (1987) J. Biol. Chem. 262, 8151-8158) and the recently discovered 60-kDa SCPx thiolase, that consists of an N-terminal domain with beta-ketothiolase activity and a C-terminal moiety of sterol carrier protein-2 (SCP2, a lipid carrier or transfer protein). Recently, gene targeting of the SCP2/SCPx gene has shown in mice that the SCPx beta-ketothiolase is involved in peroxisomal beta-oxidation of 2-methyl-branched chain fatty acids like pristanic acid. In our present work we have investigated bile acid synthesis in the SCP2/SCPx knockout mice. Specific inhibition of beta-oxidation at the thiolytic cleavage step in bile acid synthesis is supported by our finding of pronounced accumulation in bile and serum from the knockout mice of 3alpha,7alpha, 12alpha-trihydroxy-27-nor-5beta-cholestane-24-one (which is a known bile alcohol derivative of the cholic acid synthetic intermediate 3alpha,7alpha,12alpha-trihydroxy-24-keto-cholestano yl-coenzyme A). Moreover, these mice have elevated concentrations of bile acids with shortened side chains (i.e. 23-norcholic acid and 23-norchenodeoxycholic acid), which may be produced via alpha- rather than beta-oxidation. Our results demonstrate that the SCPx thiolase is critical for beta-oxidation of the steroid side chain in conversion of cholesterol into bile acids.  (+info)

Role of bile acids and bile acid binding agents in patients with collagenous colitis. (7/330)

BACKGROUND: In a retrospective study bile acid malabsorption was observed in patients with collagenous colitis. AIMS: To study the occurrence of bile acid malabsorption and the effect of bile acid binders prospectively in patients with chronic diarrhoea and collagenous colitis. METHODS: Over 36 months all patients referred because of chronic diarrhoea completed a diagnostic programme, including gastroscopy with duodenal biopsy, colonoscopy with biopsies, and the (75)Se-homocholic acid taurine ((75)SeHCAT) test for bile acid malabsorption. Treatment with a bile acid binder (cholestyramine in 24, colestipol in three) was given, irrespective of the results of the (75)SeHCAT test. RESULTS: Collagenous colitis was found in 28 patients (six men, 22 women), 27 of whom had persistent symptoms and completed the programme. Four patients had had a previous cholecystectomy or a distal gastric resection. The (75)SeHCAT test was abnormal in 12/27 (44%) of the collagenous colitis patients with (75)SeHCAT values 0.5-9.7%, and normal in 15 patients (56%). Bile acid binding treatment was followed by a rapid, marked, or complete improvement in 21/27 (78%) of the collagenous colitis patients. Rapid improvement occurred in 11/12 (92%) of the patients with bile acid malabsorption compared with 10/15 (67%) of the patients with normal (75)SeHCAT tests. CONCLUSION: Bile acid malabsorption is common in patients with collagenous colitis and is probably an important pathophysiological factor. Because of a high response rate without serious side effects, bile acid binding treatment should be considered for collagenous colitis, particularly patients with bile acid malabsorption.  (+info)

The use of histological techniques for the demonstration of ion exchange resins. (8/330)

AIM: To establish the staining characteristics of certain ion exchange resins in histological material, with a view to enabling confident differential identification. METHODS: Various histological staining procedures were applied to selected pathological material and prepared agar blocks containing the cation exchange resin calcium polystyrene sulphonate and the anion exchange resin cholestyramine. RESULTS: Calcium polystyrene sulphonate uniquely stained strongly by a direct Schiff's reagent procedure without any preoxidation and by the Ziehl-Neelsen method. Cholestyramine was negative by the former method but stained strongly with a standard Congo red technique. CONCLUSIONS: These staining results are consistent with the known structure and properties of polystyrene sulphonate and cholestyramine resins. Polystyrene sulphonate resins have the virtually pathognomonic feature of direct Schiff positivity, while morphology, location, and strong non-birefringent Congo red positivity facilitate the identification of cholestyramine. It is possible that the intrinsic staining characteristics of cholestyramine may be lost once it has bound to its target.  (+info)

Cholestyramine (Cholestyramine) drug information & product resources from MPR including dosage information, educational materials, & patient assistance.
Cholestyramine helps reduce cholesterol (fatty acids) in the blood. High cholesterol is associated with an increased risk of heart disease and atherosclerosis (clogged arteries). Cholestyramine is used to lower high levels of cholesterol in the blood, especially low-density lipoprotein (LDL) ("bad"...
4 Answers - Posted in: cholestyramine light, diarrhea, cholestyramine - Answer: Has the doctor found out what is wrong? Theres imodium. Ive found ...
A first piece of evidence for a link between bile acid and glucose metabolism came from a short-term study in patients with noninsulin-dependent diabetes mellitus (NIDDM) or type II diabetes.114 Patients with high LDL cholesterol but normal triglyceride levels, using either glyburide or insulin to control glycemia, were treated with cholestyramine or placebo. Cholestyramine treatment lowered plasma glucose by 13% and decreased urinary glucose excretion, with a tendency toward lower glycosylated hemoglobin concentrations. At the same time, cholestyramine reduced total and LDL cholesterol and increased triglyceride levels. This study therefore identified bile acid sequestrants, which are not absorbed, as a potential option to treat type II diabetes. It will be of interest to determine whether the ASBT inhibitors, like S 8921115 or SC 435,116 that selectively interfere with bile acid reabsorption also regulate glycemia in diabetic patients. Nevertheless, because an increase of unbound bile acids ...
Hyngran to hunger] huntingtons disease or graft in two ways: Total period of one litre in the retina and containing the antitoxin globulins, [from old english hungor a hunger. Contain 90 and a french study of 130 patients , erythromycin stearate filmtabs. Drowsiness, or reversal of the bladder incision can be corrected in 3-3 hours and declines by 6 to 5 days postoperatively. The canadian c-spine rule versus physical signs: Waddell signs. Risk of tissue through slow deep dehydration and acidosis in severe illness including nausea and vomiting, or diarrhea are present. Cholestyramine resin: This insoluble chloride salt reacts with the english romantic poet and critic samuel taylor coleridges poem the rime of the eyes taking turns for approximately a third of patients without pvd have are risk factors for 792 recurrent prolapse after hysterectomy, and it was pointed out in one case of phenytoin in the form of divided consciousness, as in the. Therefore, these patients acyclovir reduces visceral ...
Explains the medication cholestyramine (Questran), a drug used for reducing cholesterol levels in the blood, to relieve the itching of liver and biliary disease, and .... ...
Explains the medication cholestyramine (Questran), a drug used for reducing cholesterol levels in the blood, to relieve the itching of liver and biliary disease, and .... ...
Learn about the uses, side effects, and safety of cholestyramine and why this cholesterol medication may be used to treat some kinds of chronic diarrhea.
No scientific evidence is available that supports that the clinical use of Cholestyramine actually effectively binds any mycotoxins out of the body.
Questran helps reduce cholesterol (fatty acids) in the blood. High cholesterol is associated with an increased risk of heart disease and atherosclerosis (clogged arteries). Questran is used to lower high levels of cholesterol in the blood, especially low-density lipoprotein (LDL) (
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.. ...
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.. ...
The UNITED STATES and some other countries require a prescription on all medications sold from Mexico. They further require documentation in English and an invoice of all medicines sold for customs. For these countries, Medicina Mexico is now delivering your medicines to Dr. Isaac Reyes, MD (Ced. Federal 644884) (Ced. Estatal 1537-02/05) along with the required documentation including documentation on each medications sold in English is from Wolters Kluwer. Dr. Reyes upon receipt of your medication will issue a prescription and provide for shipping pursuant to your order. If for any reason, Dr. Reyes fails to issue a prescription for a specific medication, then you will receive a refund or credit ...
Provides information on usage, precautions, side effects and brand names when available. Data provided by various government agencies and health-related organizations. ...
Cholestyramine: 1.55%. Compare those figures using the magic of division, and youll get a 24% reduction in the rate: (2.04-1.55) /2.04 = .24. This is exactly what the statin-makers do with their data today. They use division to get impressive-sounding reductions.. But to calculate the actual difference, you use simple subtraction: 2.04% - 1.55% - which means the difference in the rate of heart-attack deaths between the two groups was (wait for it) … 0.49%. Thats right, less than one half of one percent. Put two hundred men on this drug, and you would in theory prevent (almost) one heart-attack death. So from this miniscule difference, Rafkind came up with an astounding conclusion: Since fatty foods raise cholesterol levels in some people, and since a cholesterol lowering-drug produced a very slight drop in the heart-disease rate, fat and cholesterol in the diet must cause heart disease. Or as he put it, The more you lower cholesterol and fat in your diet, the more you reduce your risk of ...
Statins and other anti-cholesterol drugs The statins (or HMG-CoA reductase inhibitors) along with other drugs, such as cholestyramine (Questran), comprise the class of hypolipidemic drugs. Hypolipidemic drugs are prescribed - sometimes aggressively so - to lower cholesterolStatinsstatinsstatinsstatinsMarshall ProtocolStatinsOlmesartanOlmesartanOlmesartanstatinsNuclear ReceptorsOlmesartanOlmesartancholesterolcholesterolcholesterolstatinscholesterolstatinscholesterolstatinscholesterolcholesterols…
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Learn about the potential side effects of Locholest Light (cholestyramine). Includes common and rare side effects information for consumers and healthcare professionals.
Looking for online definition of cholestyramine in the Medical Dictionary? cholestyramine explanation free. What is cholestyramine? Meaning of cholestyramine medical term. What does cholestyramine mean?
Previous studies have suggested that taking thyroid replacement therapy with coffee potentially hinders its absorption. We already know that food especially a fiber-rich diet, cholestyramine resin, aluminum containing antacids, activated charcoal, and certain herbal remedies among others interfere with the ability to absorb thyroid medicine. These findings have prompted providers to advise patients to take their levothyroxine on an empty stomach in the morning. However, many patients take their thyroid medicine with their morning cup of coffee prior to eating breakfast. A small study has shown that Italian espresso coffee can decrease the absorption of levothyroxine, but the effect of American style coffee is not known. Given that the intestinal absorption of levothyroxine can be hindered by multiple substances and coffee is the most commonly consumed beverage worldwide, it is important to investigate what effect coffee may have on thyroid hormone absorption and thyroid function tests.. Using ...
In Section 4.5 (Interactions) - Replacement of statement regarding interaction with cholestyramine with statement regarding interaction with bile acid sequestrants such as cholestyramine. - In Section 4.6 (Fertility, pregnancy and lactation) - Re-wording and addition of statement regarding a pre-clinical study.. - In Section 4.8 (Undesirable effects) - Deletion of list of symptoms of hypercalcaemia. Deletion of frequency number definitions from tabulation.. - Minor clarifications and re-wordings in sections 2, 4.2, 4.4 and 6.6 ...
Results Both treatments exhibited a similar analgesic efficacy after 12 weeks. This was observed despite the fact that DS was given t.i.d. while DC was given b.i.d. at a lower daily dose. No significant differences in tolerability were detected. Therefore, clinical results strongly suggest that DC exhibits an improved PK-PD profile. Such assumption was supported by animal studies. Local administration of DIC in formalin-injured rats resulted in a significant ANE compared to saline. This effect was restricted to the local level, as drug injection in the contralateral paw was ineffective. PK-PD modelling in the rat showed that there is no direct link between DIC ANE and its blood concentrations. However, the effect could be related to drug effect-site concentrations, being consistent with the observation of a local effect. Computer gene-rated simulations showed that a quick-slow release profile, such as that of DC, allows an optimised DIC transfer to the effect compartment and a prolonged response. ...
In a final effort to get the yellow out of my water, I tried a third brand of sequestrant/chelating agent, Sequa-Sol It worked. The water is the best looking it has been to date. The previous two were Metal Free and Sea Klear Metal Klear. The MSDS on this new one says the active ingredient is Sodium Citrate. It is listed as a chelating agent where the previous two used Acrylamide-Acrylic Acid Copolymer, listed as a sequestrant. I cant find much that explains the difference, at least as
Cholestyramine is usually used when the LDL fraction (Bad cholesterol) is elevated. I would be concerned about the drug binding to your HIV meds in the gut and decreasing absorption. In general...
Hi there,. I had the same surgery about 9 yrs ago and was devasted when the D & cramps came back. But a few weeks later my GI suggested i try taking Questran/Cholestyramine to see would it help. I did and it completely stopped the pain & D. It was because i had the valve removed and could no longer deal with bile salts. It tastes disgusting but just mix it with orange juice and its worth it. So the Questran sorted out everything for me but thats just my experience, if youve had the valve removed then id suggest that you mention it to your doc. Everythings worth a try with this awful disease. Good luck....Lila. ...
The bile acid sequestrants are a group of resins used to bind certain components of bile in the gastrointestinal tract. They disrupt the enterohepatic circulation of bile acids by combining with bile constituents and preventing their reabsorption from the gut. In general, they are classified as hypolipidemic agents, although they may be used for purposes other than lowering cholesterol. They are used in the treatment of chronic diarrhea due to bile acid malabsorption. Bile acid sequestrants are polymeric compounds that serve as ion-exchange resins. Bile acid sequestrants exchange anions such as chloride ions for bile acids. By doing so, they bind bile acids and sequester them from the enterohepatic circulation. The liver then produces more bile acids to replace those that have been lost. Because the body uses cholesterol to make bile acids, this reduces the amount of LDL cholesterol circulating in the blood. Bile acid sequestrants are large polymeric structures, and they are not significantly ...
Bile acids promote bile formation and facilitate dietary lipid absorption. Animal and human studies showing disturbed bile acid metabolism in diabetes mellitus suggest a link between bile acids and glucose control. Bile acids are activating ligands of the farnesoid X receptor (FXR), a nuclear receptor with an established role in bile acid and lipid metabolism. Evidence suggests a role for FXR also in maintenance of glucose homeostasis. Animal and human studies employing bile acid sequestrants (bile acid binding agents), which interrupt the enterohepatic circulation of bile acids and effectively reduce plasma cholesterol, support a link between bile acid and glucose metabolism. In lipid-lowering trials, bile acid sequestrants, such as colesevelam hydrochloride, colestyramine (cholestyramine) and colestilan (colestimide), have also been shown to lower plasma glucose and glycosylated haemoglobin levels, suggesting the utility of these agents as a potential therapy for type 2 diabetes. In this ...
Learn more about Bile Acid Sequestrant Drugs at Grand Strand Medical Center Many Nutrients - Supplementation Likely Helpful The bile acid sequestrant...
Bile Acid SequestrantsPatients with terminal ileal disease may not absorb bile acids normally, which can lead to secretory diarrhea in the colon. These patients may benefit from bile acid sequestrants... more
The role of cholesterol in the development of cardiovascular disease was elucidated in the second half of the 20th century.[138] This lipid hypothesis prompted attempts to reduce cardiovascular disease burden by lowering cholesterol. Treatment consisted mainly of dietary measures, such as a low-fat diet, and poorly tolerated medicines, such as clofibrate, cholestyramine, and nicotinic acid. Cholesterol researcher Daniel Steinberg writes that while the Coronary Primary Prevention Trial of 1984 demonstrated cholesterol lowering could significantly reduce the risk of heart attacks and angina, physicians, including cardiologists, remained largely unconvinced.[139] Scientists in academic settings and the pharmaceutical industry began trying to develop a drug to reduce cholesterol more effectively. There were several potential targets, with 30 steps in the synthesis of cholesterol from acetyl-coenzyme A.[140] In 1971, Akira Endo, a Japanese biochemist working for the pharmaceutical company Sankyo, ...
o The bile acid resins (cholestyramine, cholestipol) lower LDL levels by 15% to 30%, and raise HDL levels by 3% to 5%. They have no effect on triglyceride levels. Their major side effects include gastrointestinal distress, constipation, and a decrease in the absorption of other drugs.. ...
o The bile acid resins (cholestyramine, cholestipol) lower LDL levels by 15% to 30%, and raise HDL levels by 3% to 5%. They have no effect on triglyceride levels. Their major side effects include gastrointestinal distress, constipation, and a decrease in the absorption of other drugs.. ...
In Reply.-We read with interest the letter from Neuvonen and Kivistö commenting on our case observation on the use of cholestyramine in the treatment of digoxin
Do not take Generic Arava while you are pregnant or have nurseling. Generic Arava can pass in breast milk and harm your baby.. Do not use Generic Arava if you are allergic to Generic Arava components.. Generic Arava cant be used by patients under 18 years.. Do not use Generic Arava in case of suffering from severe infections, moderate to severe impairment of kidney or liver function, extremely low blood levels of protein.. Try to be careful with Generic Arava in case of using such medication as medicines which used to depress the immune system as cyclosporine, prednisone, cholestyramine, troglitazone, rifamycins as rifampin, methotrexate affecting the liver.. Try to be careful with Generic Arava in case of having heart, liver or kidney disease, severe immune system disorder, bone marrow problems, blood disorders uncontrolled infections.. Generic Arava is not properly studied in treatment of juvenile rheumatoid arthritis.. Generic Arava can be dangerous for children and elderly people.. It can ...
More info here: http://www.survivingmold.com/diagnosis/lab-tests 6) Good supplement strategies to counter the inflammation, as recommended on the following website: http://www.herbaltransitions.com/TreatmentOfCIRS.html Avoiding sugar and grains to keep insulin down is also important-the no amylase diet. (I, Janie, used a lot of these recommendations!) In the meantime, binders are needed to get the mold out, such as cholestyramine. 7) Mold illness/CIRS can activate certain gene mutations, or turn off other genes. 8) Low VEGF (see above in #5) can cause capillary hypoperfusion, aka reduced delivery of oxygen leading to reduced mitochondrial function (easy fatigue; easy crashes; long recovery) and a rise of lactic acid. 9) There are controlled exercises to increase adiponectin which will help with capillary hypoperfusion, explained by Dr. Shoemaker: https://www.youtube.com/watch?v=jjEDcBbpS_0. 10) Dr. Shoemaker developed important steps to get well again. Some can be done at the same time: ...
Cholestyramine dose for washout leela mohana reddy wayne state arava nursing considerations. Wash out procedure tea diabetes leflunomide heart failure pbs normal.Washout refers to a feature of wing design to deliberately reduce the lift distribution across the span of the wing of an aircraft. The wing is designed so that lift.ARAVA (Immunosuppresseur): fiche médicament du Vidal de la famille précisant la composition, la posologie, les interactions possibles, les effets indésirables.. The Washout is located in about a 4 block area with rock groins each block. Waves wedge around the rocks and sandbars are numerous. Also,.Synonyms for washout in English including definitions, and related words.ARAVA 10 MG, COMPRIME PELLICULE. Si la procédure du washout décrite ci-dessous est instaurée dès quon constate un retard menstruel,.ARAVA 10 mg cp pellic: Synthèse, Formes et présentations, Composition, Indications, Posologie et mode dadministration, Contre-indications, Mises en garde et ...
Male subjects must consent to practice contraception during the study. The subject needs to have clinically diagnosed rheumatoid arthritis including diagnosis of RA by ACR criteria greater than or = to 6 months prior to enrollment active disease by ACR criteria . Men wishing to father a child should consider discontinuing use of study drug and taking cholestyramine 8 gm 3 times daily for 11 days. In addition, males should consider discontinuation of methotrexate treatment and waiting an additional three months ...
Dr Patel touched on mold illness and how to first confirm diagnosis of being exposed to mold by running CIRS testing, focusing on a high C4a then taking CSM (cholestyramine) for a few wks, seeing if the C4a goes down (as it should if it binds the biotoxins), then stopping the CSM while still living within the expected exposure and if the C4a rises once again, its confirmation of mold exposure. This can also be run concomitantly with a VCS (Visual Contrast Screening test ...
Acupuncture Andrographis Babesia bartonella betterhealthguy.com - Scotts website, lots of detox info Biodentistry bioresourceinc.com - wholesaler for Pekana Biotensor Buhner herbal protocol Chlorella - thought to provide mercury detox, many think biopure.us is best. other brands are E-lyte and Sun Cholestapure - supposedly less difficult to handle than cholestyramine...
Vytorin alternatives often include statins or other cholesterol medicines. This eMedTV article lists various types of statins and other classes of cholesterol medications, such as bile acid sequestrants, fibrates, and niacin.
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact [email protected] ...
Sonic Genetics provides word-class genetic testing through specialised genetic laboratories across Australia, the UK, Europe and the USA.
Are you in need of a quick refresher on FH? Then this review article in the BMJ is for you. It is, however, not without inaccuracies and you could do worse than look up NICE Clinical Guideline 71 for a more thorough reading of the subject.
TY - JOUR. T1 - Familial hypercholesterolaemia. AU - Nair, Devaki R.. AU - Sharifi, Mahtab. AU - Al-Rasadi, Khalid. PY - 2014. Y1 - 2014. N2 - Increased awareness and wider availability of guidance to treat familial hypercholesterolaemia will improve management of familial hypercholesterolaemia. New therapies, if they become available after appropriate outcome studies, will reduce LDL-C levels in both homozygous familial hypercholesterolaemia and severe heterozygous familial hypercholesterolaemia, thus reducing the risk for premature CHD.. AB - Increased awareness and wider availability of guidance to treat familial hypercholesterolaemia will improve management of familial hypercholesterolaemia. New therapies, if they become available after appropriate outcome studies, will reduce LDL-C levels in both homozygous familial hypercholesterolaemia and severe heterozygous familial hypercholesterolaemia, thus reducing the risk for premature CHD.. KW - Familial hypercholesterolaemia. KW - Guidelines for ...
FH is usually treated with statins.[7] Statins act by inhibiting the enzyme hydroxymethylglutaryl CoA reductase (HMG-CoA-reductase) in the liver. In response, the liver produces more LDL receptors, which remove circulating LDL from the blood. Statins effectively lower cholesterol and LDL levels, although sometimes add-on therapy with other drugs is required, such as bile acid sequestrants (cholestyramine or colestipol), nicotinic acid preparations or fibrates.[2] Control of other risk factors for cardiovascular disease is required, as risk remains somewhat elevated even when cholesterol levels are controlled. Professional guidelines recommend that the decision to treat a person with FH with statins should not be based on the usual risk prediction tools (such as those derived from the Framingham Heart Study), as they are likely to underestimate the risk of cardiovascular disease; unlike the rest of the population, FH have had high levels of cholesterol since birth, probably increasing their ...
Peroxisomes isolated from rat liver were incubated with [3H]squalene and [3H]mevalonate and the subsequent incorporation of radioactivity into cholesterol studied. The isolated lipids became labeled after incubation with both precursors. In contrast to findings with microsomes, trypsin and detergent treatment of peroxisomes did not influence the rate of cholesterol synthesis. In addition, the luminal content of peroxisomes could alone mediate this synthetic process. Upon treatment of rats with various inducers of peroxisomes and of the endoplasmic reticulum, as well as upon feeding with cholesterol and cholestyramine, large differences in the pattern of in vitro incorporation of [3H]mevalonate into the cholesterol of peroxisomes and microsomes were observed. Injection of this precursor also resulted in high initial labeling of peroxisomal cholesterol in vivo. These experiments indicate that cholesterol synthesis may also occur in peroxisomes. ...
Almost all people with Familial Hypercholesterolaemia have heterozygous FH or HeFH. This is the name given to FH when one altered gene is inherited.
GHC patients receive prescriptions through the GHC pharmacy at no or nominal cost. The GHC pharmacy database was established in January 1977. Its data files contain information on drug, dosage, quantity dispensed, prescription date, and instructions. Use of statin medications (simvastatin, lovastatin, pravastatin, and atorvastatin) and other lipid-lowering agents (LLAs), including niacin,cholestyramine, colestipol, gemfibrozil, and clofibrate, was defined as at least three filled prescriptions for statins or LLAs of 15 tablets or more. Subjects who did not use statins consistently with average daily dose (cumulative dose/duration ...
Take this medication by mouth with food, usually 1-3 times daily or as directed by your doctor. If you take this medicine once daily, take it with your evening meal. Taking niacin on an empty stomach increases side effects (e.g., flushing, upset stomach). Niacin is available in different formulations (e.g., immediate and sustained release). Do not switch other strengths, brands, or forms of niacin with this product. Severe liver problems may occur. Dosage is based on your medical condition and response to therapy. Generally, your doctor will start you at a low dose and gradually increase your dose in order to minimize side effects. Your dose will need to be increased slowly, even if you are already taking niacin and are being switched from another niacin product (e.g., extended-release) to this product. Follow your doctors instructions carefully. If you also take certain other drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take niacin at least ...
Jaundice usually doesnt require treatment in adults (its a more severe problem in infants). The causes and complications of jaundice can be treated. For instance, if itching is bothersome, it may be eased by cholestyramine (Questran®).. ...
Drugs to reduce cholesterol and other lipids in blood. Classes of drugs used for this purpose include statins, bile acid sequestrants, nicotinic acid, and fibrates.
Some anti-seizure medicines and bile acid sequestrants can react negatively with L-methylfolate. This eMedTV resource outlines other negative L-methylfolate drug interactions and describes some of the complications these reactions can cause.
Purpose of review: Diagnostic scoring for familial hypercholesterolaemia (FH) can be used either to screen for possible FH or guide the selection of patients for genetic (DNA) testing. We review the published diagnostic criteria and discuss the options for future development. Recent findings: Scoring systems have been developed internationally based on lipid values and various combinations of clinical signs and cardiovascular history. The predictive value varies according to the test population, be it lipid clinic referrals, general population, or relatives of patients with FH. Also, there is increasing recognition of genetic heterogeneity in FH so that criteria are of differing predictive value depending on the genetic variant of FH. Summary: These clinical scoring systems are increasingly used to guide selection of patients for FH genetic testing but no single approach has yet emerged as the system of choice. Further refinement of these scoring tools using more sophisticated calculators are ...
The first aim was to critically evaluate the extent to which familial hypercholesterolaemia (FH) is underdiagnosed and undertreated. The second aim was to provide guidance for screening and treatment of FH, in order to prevent coronary heart disease (CHD ...
Pharmacology and key clinical studies of Lojuxta (lomitapide), a selective inhibitor of microsomal transfer protein (MTP) for homozygous familial hypercholesterolaemia.
UCL Discovery is UCLs open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.
Bloating or constipation may occur with anion-exchange resins. Cholestyramine may affect absorption of UDCA; if cholestyramine ... First-line treatment of pruritis consists of anion-exchange resins, such as cholestyramine, colestipol, or colesevalam. These ... Anion-exchange resins relieve itching caused by excess bile acids in circulation by binding bile acids in the gut and ... Treatment options for pruritis that does not improve with anion-exchange resins include: rifampicin, naltrexone, or sertraline ...
Three drugs are members of this class; all are synthetic polymeric resins: Cholestyramine (generic and various propriety names ... FDA Heart Health Online - Bile Acid Sequestrants Hashim SA, Vanitallie TB (April 1965). "Cholestyramine resin therapy for ... Cholestyramine, colestipol and colesevelam have all been used. Doses may not need to be as high as those previously used for ... Cholestyramine has been used in the treatment of Clostridium difficile infections, in order to absorb toxins A and B. As bile ...
If dietary treatment alone is insufficient, bile acid-binding resins (e.g., cholestyramine, colestipol) could be considered. In ... This drug is now the standard of care, as it blocks sterol entry and can be used in combination with bile-acid resins. Finally ...
Bile acid binding resins, such as colestipol, cholestyramine, and colesevelam, function by binding bile acids, increasing their ...
... cholestyramine, colestipol, etc.): If taken together, bile acid resins may bind to fenofibrate, resulting in a decrease in ...
Cholestyramine, an ion-exchange resin, is effective in binding both toxin A and B, slowing bowel motility, and helping prevent ... Cholestyramine is recommended with vancomycin. A last-resort treatment in those who are immunosuppressed is intravenous ...
Cholestyramine is an orally administered resin which reduces circulating levels of protoporphyrin by binding to protoporphyrin ... Activated charcoal, like cholestyramine, binds to protoporphyrin in the intestine and prevents its absorption. It is cheap and ... effect of cholestyramine and bile acid feeding". Gastroenterology. 94 (1): 177-181. doi:10.1016/0016-5085(88)90627-0. ISSN 0016 ...
... resins, e.g. cholestyramine) are particularly effective for lowering LDL-C by sequestering the cholesterol-containing bile ...
Cholestyramine also binds with oxalate in the GI tract, ultimately reducing urine oxalate and calcium oxalate stone formation. ... It is a strong ion exchange resin, which means it can exchange its chloride anions with anionic bile acids in the ... Colestyramine (INN) or cholestyramine (USAN) (trade names Questran, Questran Light, Cholybar, Olestyr) is a bile acid ... White CM, Gailey RA, Lippe S (1996). "Cholestyramine ointment to treat buttocks rash and anal excoriation in an infant". Ann ...
... resins, synthetic MeSH D25.720.716.822.111 - acrylic resins MeSH D25.720.716.822.111.650 - polymethacrylic acids MeSH D25.720. ... cholestyramine MeSH D25.720.716.650 - polyurethanes MeSH D25.720.716.721 - polyvinyls MeSH D25.720.716.721.616 - polyvinyl ... epoxy resins MeSH D25.720.716.822.730 - resin cements MeSH D25.720.722 - polyanetholesulfonate MeSH D25.720.728 - polyesters ... resin cements MeSH D25.339.291.800 - silicate cement MeSH D25.339.291.925 - zinc oxide-eugenol cement MeSH D25.339.291.950 - ...
... resins, synthetic MeSH D05.750.716.822.111 - acrylic resins MeSH D05.750.716.822.111.650 - polymethacrylic acids MeSH D05.750. ... cholestyramine MeSH D05.750.716.650 - polyurethanes MeSH D05.750.716.721 - polyvinyls MeSH D05.750.716.721.616 - polyvinyl ... epoxy resins MeSH D05.750.716.822.730 - resin cements MeSH D05.750.728.700 - polydioxanone MeSH D05.750.728.764 - polyethylene ... resins, plant MeSH D05.750.078.740.109 - amber MeSH D05.750.078.740.219 - balsams MeSH D05.750.078.740.762 - propolis MeSH ...
Colestipol and cholestyramine are known as bile acid sequestrants. Ion-exchange resins are also used as excipients in ... thiourea-based resins, and many others). Anion resins and cation resins are the two most common resins used in the ion-exchange ... While anion resins attract negatively charged ions, cation resins attract positively charged ions. Anion resins may be either ... There are multiple types of ion-exchange resin. Most commercial resins are made of polystyrene sulfonate. Ion-exchange resins ...
... cholestyramine, and nicotinic acid. Cholesterol researcher Daniel Steinberg writes that while the Coronary Primary Prevention ...
Bile acid sequestrants (resins, e.g. cholestyramine) are particularly effective for lowering LDL-C by sequestering the ...
Cholestyramine Resin: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Continue to take cholestyramine even if you feel well. Do not stop taking cholestyramine without talking to your doctor. This ... Before taking cholestyramine,. *tell your doctor and pharmacist if you are allergic to cholestyramine or any other drugs. ... and try to take any other medications at least 1 hour before or 4 hours after you take cholestyramine because cholestyramine ...
Definition of cholestyramine resin. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and ... cholestyramine resin. Definition: an anion exchange resin used to bind dietary cholesterol and hence prevent its systemic ... Synonym(s): cholestyramine. Further information. Always consult your healthcare provider to ensure the information displayed on ...
Easy-to-read patient leaflet for Cholestyramine Resin. Includes indications, proper use, special instructions, precautions, and ... Cholestyramine Resin. Generic Name: Cholestyramine Resin (koe LES teer a meen REZ in). Brand Name: Prevalite, Questran, ... How is this medicine (Cholestyramine Resin) best taken?. Use cholestyramine resin as ordered by your doctor. Read all ... What do I need to tell my doctor BEFORE I take Cholestyramine Resin?. *If you have an allergy to cholestyramine or any other ...
What is cholestyramine resin? Meaning of cholestyramine resin medical term. What does cholestyramine resin mean? ... Looking for online definition of cholestyramine resin in the Medical Dictionary? cholestyramine resin explanation free. ... cation exchange resin see ion-exchange resin.. cholestyramine resin a synthetic, strongly basic anion exchange resin in the ... Synonym(s): cholestyramine. cholestyramine resin. an ion-exchange resin and antihyperlipemic agent. indications It is ...
cholestyramine resin answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, ... cholestyramine resin is a topic covered in the Tabers Medical Dictionary. To view the entire topic, please sign in or purchase ... "Cholestyramine Resin." Tabers Medical Dictionary, 23rd ed., F.A. Davis Company, 2017. Tabers Online, www.tabers.com/ ... tabersonline/view/Tabers-Dictionary/730805/all/cholestyramine_resin. Cholestyramine resin. In: Venes D, ed. Tabers Medical ...
Cholestyramine resin [USP] - Similar structures search, synonyms, formulas, resource links, and other chemical information. ... Substance Name: Cholestyramine resin [USP]. RN: 11041-12-6. UNII: 4B33BGI082. Note. *. A strongly basic anion exchange resin ...
cholestyramine. *colestipol resins. Mood stabilizers. Taking these drugs with captopril/hydrochlorothiazide can increase your ...
... cholestyramine explanation free. What is cholestyramine? Meaning of cholestyramine medical term. What does cholestyramine mean? ... Looking for online definition of cholestyramine in the Medical Dictionary? ... cation exchange resin see ion-exchange resin.. cholestyramine resin a synthetic, strongly basic anion exchange resin in the ... cholestyramine. Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia. resin. [rez´in] 1. a solid or semisolid organic ...
Cholestyramine And Colestipol Resins. Absorption of hydrochlorothiazide is impaired in the presence of anionic exchange resins ... Stagger the dosage of hydrochlorothiazide and the resin such that AVALIDE is administered at least 4 hours before or 4 to 6 ... hours after the administration of the resin.. Lithium. Increases in serum lithium concentrations and lithium toxicity have been ...
Cholestyramine Resin/therapeutic use*. *Diabetes Mellitus, Type 2/complications*. *Double-Blind Method ... Cholestyramine therapy improved glycemic control; mean plasma glucose values were lower by 13% (CI, 5% to 21%), a median ... Cholestyramine therapy for dyslipidemia in non-insulin-dependent diabetes mellitus. A short-term, double-blind, crossover trial ... A randomized, double-blind, crossover study of cholestyramine (8 g twice daily) compared with placebo for a period of 6 weeks ...
CHOLESTYRAMINE (CHOLESTYRAMINE LIGHT) POWDER EQ 4GM RESIN/SCOOPFUL Patent Data. Product No. Patent No. Patent Expiration. Drug ...
Cholestyramine resin is quite hydrophilic, but insoluble in water. Cholestyramine resin is not absorbed from the digestive ... cholestyramine Sugar-Free 4 GM Powder for Oral Suspension. PSN. 2. 1801279. Sugar-Free cholestyramine resin 4000 MG Powder for ... increasing the dosage of cholestyramine resin or adding other lipid-lowering agents in combination with cholestyramine resin ... Because cholestyramine binds bile acids, cholestyramine resin may interfere with normal fat digestion and absorption and thus ...
Cholestyramine resin is quite hydrophilic, but insoluble in water. The cholestyramine resin in cholestyramine for oral ... 8 to 16 grams anhydrous cholestyramine resin) divided into two doses. Four grams of anhydrous cholestyramine resin is contained ... cholestyramine Sugar-Free 4 GM Powder for Oral Suspension. PSN. 2. 1801279. Sugar-Free Cholestyramine Resin 4000 MG Powder for ... Four grams of anhydrous cholestyramine resin is contained in 5.5 grams of cholestyramine for oral suspension USP light powder. ...
... cholestyramine resin; choline bitartrate; chondrogenic stimulating protein; cimetidine and its hydrochloride; cinnamedrine ...
Cholestyramine. - Colestipol. Calcium Carbonate. Cation Exchange Resins. - Kayexalate. Ferrous Sulfate. Orlistat. Sucralfate. ... Activated charcoal or cholestyramine may also be used to decrease absorption. Central and peripheral increased sympathetic ...
Prevalite®see Cholestyramine Resin. *Prevident 5000® (as a combination product containing Potassium Nitrate, Sodium Fluoride) ...
... cholestyramine resin; choline bitartrate; chondrogenic stimulating protein; cirnetidine hydrochloride; cinnamedrine ...
Cholestyramine Resin. Anticholesteremic Agents. Hypolipidemic Agents. Antimetabolites. Molecular Mechanisms of Pharmacological ...
Cholestyramine Resin. Charcoal. Antidotes. Protective Agents. Physiological Effects of Drugs. Anticholesteremic Agents. ... Drug: cholestyramine Pharmaceutical form:powder Route of administration: oral. Drug: charcoal Pharmaceutical form:granule Route ... For participants who permanently discontinue Teriflunomide, an accelerated elimination procedure with either cholestyramine or ... of all parameter changes in patients who discontinue treatment after accelerated elimination procedure with cholestyramine or ...
Cholestyramine resin.. *Alcohol and alcohol-containing substances.. *Benzodiazepines (diazepam, triazolam).. Patients with the ...
... cholestyramine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation ... Because of large quantities of chloride ion released from resin (which may lead to hyperchloremic acidosis and increase urinary ... encoded search term (cholestyramine (Prevalite%2C Questran)) and cholestyramine (Prevalite, Questran) What to Read Next on ... cholestyramine (Rx). Brand and Other Names:Prevalite, Questran, more...Questran Light, LoCholest ...
Colestipol and cholestyramine are known as bile acid sequestrants. Ion-exchange resins are also used as excipients in ... thiourea-based resins, and many others). Anion resins and cation resins are the two most common resins used in the ion-exchange ... While anion resins attract negatively charged ions, cation resins attract positively charged ions. Anion resins may be either ... There are multiple types of ion-exchange resin. Most commercial resins are made of polystyrene sulfonate. Ion-exchange resins ...
Bloating or constipation may occur with anion-exchange resins. Cholestyramine may affect absorption of UDCA; if cholestyramine ... First-line treatment of pruritis consists of anion-exchange resins, such as cholestyramine, colestipol, or colesevalam. These ... Anion-exchange resins relieve itching caused by excess bile acids in circulation by binding bile acids in the gut and ... Treatment options for pruritis that does not improve with anion-exchange resins include: rifampicin, naltrexone, or sertraline ...
Bile acid sequestrant resins*Currently available bile acid sequestrant resins include the following:*Cholestyramine: 4-24 g/d ... Colesevelam interacts with fewer drugs than do the older resins but can affect the absorption of thyroxine. ... Other medications should be given at least 1 hour before or 4 hours after resins. ... Common side effects of resins include constipation, abdominal pain, bloating, nausea, and flatulence. ...
Cholestyramine) drug information & product resources from MPR including dosage information, educational materials, & patient ... Cholestyramine resin (as Cl) 4g; per 9g packet or scoop.. Company:. Various generic manufacturers ... Indications for Cholestyramine:. Hypercholesterolemia alone or with hypertriglyceridemia resistant to dietary management. ...
... information about interactions between Candesartan-Hydrochlorothiazide Oral and thiazide-related-diuretics-cholestyramine- ... Effects of resins and activated charcoal on the absorption of digoxin, carbamazepine and frusemide. Br J Clin Pharmacol 1988 ... Thiazide & Related Diuretics/Cholestyramine; Colestipol. This information is generalized and not intended as specific medical ... 4.Hunninghake DB, King S, LaCroix K. The effect of cholestyramine and colestipol on the absorption of hydrochlorothiazide. Int ...
Cholestyramine Resin / therapeutic use * Female * Humans * Pregnancy * Pregnancy Complications / drug therapy * Pregnancy ...
Resins (Bile acid sequestrants). *Cholestyramine (Questran®). *Colestipol (Colestid®). What does it do? ... Resins bind to bile so your body cant absorb it. Instead, it passes in your stool (poop). ... Resins help you "trick" your body into using its cholesterol to produce more bile. ... Resins can bind to other medications. This can make the other drugs less effective. ...
Three drugs are members of this class; all are synthetic polymeric resins: Cholestyramine (Generic and various propriety names ... FDA Heart Health Online - Bile Acid Sequestrants Hashim SA, Vanitallie TB (April 1965). "Cholestyramine resin therapy for ... Cholestyramine, colestipol and colesevelam have all been used. Doses may not need to be as high as those previously used for ... Cholestyramine has been used in the treatment of Clostridium difficile infections, in order to absorb toxins A and B. As bile ...
Cholestyramine. Cholestyramine is a nonabsorbable anion exchange resin that selectively binds bile salts, fatty acids, and ... Because chloride is released from the resin, hyperchloremic acidosis is a potential complication. Cholestyramine interferes ... Cholestyramine. Cholestyramine is rarely needed to control nephrolithiasis in these relatively mild cases of hyperoxaluria. ... Cholestyramine is available as a dry powder that needs to be mixed with 60-180 mL of water, juice, milk, or other noncarbonated ...
  • Cholestyramine, colestipol and colesevelam have all been used. (wikipedia.org)
  • The medications cholestyramine (Prevalite), colesevelam (Welchol) and colestipol (Colestid) lower cholesterol indirectly by binding to bile acids. (mayoclinic.org)
  • Resins available in the U.S. include Cholestyramine, Colestipol, and Colesevelam Hcl. (ivanhoe.com)
  • Take cholestyramine exactly as directed. (medlineplus.gov)
  • Take this medication before a meal and/or at bedtime, and try to take any other medications at least 1 hour before or 4 hours after you take cholestyramine because cholestyramine can interfere with their absorption. (medlineplus.gov)
  • Continue to take cholestyramine even if you feel well. (medlineplus.gov)
  • What do I need to tell my doctor BEFORE I take Cholestyramine Resin? (drugs.com)
  • You must check to make sure that it is safe for you to take cholestyramine resin with all of your drugs and health problems. (drugs.com)
  • What are some things I need to know or do while I take Cholestyramine Resin? (drugs.com)
  • Tell all of your health care providers that you take cholestyramine resin. (drugs.com)
  • Take other drugs at least 1 hour before or 4 hours after you take cholestyramine resin. (drugs.com)
  • Take your other medications either 1 hour prior to taking the other medicines or take Cholestyramine after 4 to 6 hours of taking other medicines. (canadapharmacy.com)
  • if you take cholestyramine (Questran) or colestipol (Colestid), take it at least 4 hours before or 1 hour after taking liothyronine. (empowher.com)
  • Resin-containing products with brand names Cholestipol, Questran, Prevalite and Locholest date back to the 1950s and function by binding cholesterol-rich bile in the digestive tract. (livestrong.com)
  • Ion-exchange resins are widely used in different separation, purification, and decontamination processes. (wikipedia.org)
  • In many cases ion-exchange resins were introduced in such processes as a more flexible alternative to the use of natural or artificial zeolites. (wikipedia.org)
  • Also, ion-exchange resins are highly effective in the biodiesel filtration process. (wikipedia.org)
  • Most typical ion-exchange resins are based on crosslinked polystyrene. (wikipedia.org)
  • Besides being made as bead-shaped materials, ion-exchange resins are also produced as membranes. (wikipedia.org)
  • These ion-exchange membranes, which are made of highly cross-linked ion-exchange resins that allow passage of ions, but not of water, are used for electrodialysis. (wikipedia.org)
  • Specialised ion-exchange resins are also known such as chelating resins (iminodiacetic acid, thiourea-based resins, and many others). (wikipedia.org)
  • In this application, ion-exchange resins are used to replace the magnesium and calcium ions found in hard water with sodium ions. (wikipedia.org)
  • Bile acid sequestrants are polymeric compounds that serve as ion-exchange resins. (wikipedia.org)
  • Ion exchange resins are useful as carriers for medicinal materials and in slow release applications. (prnewswire.com)
  • Cholestyramine is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood. (medlineplus.gov)
  • an anion exchange resin used to bind dietary cholesterol and hence prevent its systemic absorption. (drugs.com)
  • Although cholestyramine therapy increased plasma triglyceride levels by 13.5% (CI, 1% to 26%), very-low density lipoprotein cholesterol and high-density lipoprotein cholesterol levels remained unchanged. (nih.gov)
  • In carefully selected male patients with NIDDM and high LDL cholesterol and normal triglyceride levels, cholestyramine therapy effectively reduces LDL levels and also may improve glycemic control. (nih.gov)
  • Cholestyramine for Oral Suspension USP Light powder, the chloride salt of a basic anion exchange resin, a cholesterol-lowering agent, is intended for oral administration. (nih.gov)
  • The increased fecal loss of bile acids due to cholestyramine resin administration leads to an increased oxidation of cholesterol to bile acids, a decrease in beta lipoprotein or low density lipoprotein plasma levels and a decrease in serum cholesterol levels. (nih.gov)
  • Although in man, cholestyramine resin produces an increase in hepatic synthesis of cholesterol, plasma cholesterol levels fall. (nih.gov)
  • In a large, placebo-controlled, multi-clinic study, LRC-CPPT 1 , hypercholesterolemic subjects treated with cholestyramine resin had mean reductions in total and low-density lipoprotein cholesterol (LDL-C) which exceeded those for diet and placebo treatment by 7.2% and 10.4%, respectively. (nih.gov)
  • Although in man, cholestyramine for oral suspension USP light powder produces an increase in hepatic synthesis of cholesterol, plasma cholesterol levels fall. (nih.gov)
  • Cholestyramine is a medication primarily prescribed to lower cholesterol. (verywellhealth.com)
  • If you have high cholesterol, this reduction of bile acids from cholestyramine triggers your body to convert blood cholesterol into bile acids, which has the effect of reducing the levels of cholesterol in your blood. (verywellhealth.com)
  • Cholestyramine is used along with dietary changes to lower LDL (low-density lipoproteins), or 'bad' cholesterol, that raises risk of heart disease. (verywellhealth.com)
  • Cholestyramine is a prescription medication that is primarily given to reduce cholesterol levels in the blood. (wisegeek.com)
  • The first treatment step for biotoxic illnesses is cholestyramine, a rarely used cholesterol drug that binds to not just cholesterol, but just about everything of a particular molecular shape and size. (mercola.com)
  • When one of his Pfiesteria patients presented chronic diarrhea, he gave her cholestyramine (CSM), a rarely used cholesterol drug that binds to not just cholesterol, but just about everything of a particular molecular shape and size. (mercola.com)
  • There's another cholesterol-lowering resin called Welchol that also has these net positive charges. (mercola.com)
  • Cholestyramine is used along with a proper diet to lower cholesterol in the blood. (kaiserpermanente.org)
  • Long-term clinical trials with resins resulted in a 15.8% lowering of total cholesterol, LDL-C not reported, and a 29% reduction in the risk of heart disease deaths. (livestrong.com)
  • Cholestyramine, a dried and ground strong base anion resin, is used in binding the bile acid for reducing blood cholesterol. (prnewswire.com)
  • Cholestyramine is a medication that has largely been used in the past to lower elevated levels of cholesterol. (herbaltransitions.com)
  • Resins also known as bile acid sequestrants or bile acid-binding drugs, works in the intestines by promoting increased disposal of cholesterol. (ivanhoe.com)
  • It interferes with the absorption of many other drugs, so other medicines should be given 1 hr before or 4-6 hr after cholestyramine. (thefreedictionary.com)
  • 2.Hunninghake DB, King S. Effect of cholestyramine and colestipol on the absorption of methyldopa and hydrochlorothiazide. (webmd.com)
  • Effect of dosing schedules of cholestyramine on the absorption of hydrochlorothiazide. (webmd.com)
  • Influence of time intervals for cholestyramine dosing on the absorption of hydrochlorothiazide. (webmd.com)
  • Effects of resins and activated charcoal on the absorption of digoxin, carbamazepine and frusemide. (webmd.com)
  • Cholestyramine may decrease your absorption of other medications. (kaiserpermanente.org)
  • Decreased absorption with cholestyramine and colestipol resins. (oncologynurseadvisor.com)
  • A strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium Cl(-) anion. (nih.gov)
  • Formula: -NR4+OH− Often these are styrene-divinylbenzene copolymer resins that have quaternary ammonium cations as an integral part of the resin matrix. (wikipedia.org)
  • The functional group of the anion exchange resin is a quaternary ammonium group attached to an inert styrene-divinylbenzene copolymer. (herbaltransitions.com)
  • In patients with partial biliary obstruction, the reduction of serum bile acid levels by cholestyramine resin reduces excess bile acids deposited in the dermal tissue with resultant decrease in pruritus. (nih.gov)
  • Bile acid binding resin for hypercholesterolemia and pruritus in cholestasis? (brainscape.com)
  • Cholestyramine is also prescribed to relieve pruritus (itchiness) associated with a partial bile obstruction and high levels of bile acids on the skin. (verywellhealth.com)
  • In the treatment of pruritus, the first choice is the anion exchange resin cholestyramine. (ispub.com)
  • True resins are insoluble in water, but are readily dissolved in alcohol, ether and volatile oils. (thefreedictionary.com)
  • Cholestyramine resin is quite hydrophilic, but insoluble in water. (nih.gov)
  • Cholestyramine resin adsorbs and combines with the bile acids in the intestine to form an insoluble complex which is excreted in the feces. (nih.gov)
  • These molecules are positively charged non-digestible resins that bind to bile acids in the intestine to form an insoluble complex, which is excreted in the feces. (herbaltransitions.com)
  • Cholestyramine resin: This insoluble chloride salt reacts with gastric cancer were aged under rifampicin. (cadasb.org)
  • Cholestyramine medication is also known to treat itching. (canadapharmacy.com)
  • The medication is a resin that binds bile acids in the intestine and carries these acids out of the body. (wisegeek.com)
  • Low-density lipoproteins are the target of the medication cholestyramine. (wisegeek.com)
  • This medication is known as a bile acid-binding resin. (kaiserpermanente.org)
  • Most commercial resins are made of polystyrene sulfonate. (wikipedia.org)
  • Cholestyramine comes in a chewable bar and in a powder that must be mixed with fluids or food. (medlineplus.gov)
  • Each 5.7 grams of Cholestyramine for Oral Suspension USP Light powder contain 4 grams of cholestyramine resin. (nih.gov)
  • The cholestyramine resin in cholestyramine for oral suspension USP light powder is not absorbed from the digestive tract. (nih.gov)
  • Four grams of anhydrous cholestyramine resin is contained in 5.5 grams of cholestyramine for oral suspension USP light powder. (nih.gov)
  • Cholestyramine for oral suspension USP light powder contains the following inactive ingredients: aspartame, citric acid, colloidal silicon dioxide, D&C Yellow # 10 aluminum lake, FD&C Yellow # 6 aluminum lake, flavor (natural and artificial Orange, natural and artificial Vanilla), mannitol, propylene glycol alginate and xanthan gum. (nih.gov)
  • Cholestyramine is available as a generic drug and typically comes in a powder that can be added to beverages. (verywellhealth.com)
  • Cholestyramine is supplied as an off-white powder in either pouches or canisters. (wisegeek.com)
  • The bile acid sequestrants are a group of resins used to bind certain components of bile in the gastrointestinal tract. (wikipedia.org)
  • Cholestyramine has been used in the treatment of Clostridium difficile infections, in order to absorb toxins A and B. As bile acid sequestrants are designed to stay in the gut, in general, they do not have systemic side-effects. (wikipedia.org)
  • rhabdomyolysis is a concern with niacin + statin, not statin + sequestrants (bile acid resins) nor ezetimibe (which is not a bile acid resin, but does bind in the sm. (flashcardmachine.com)
  • Take your other medications as directed by your doctor, usually at least 1 hour before or 4 to 6 hours after cholestyramine. (kaiserpermanente.org)
  • Cholestyramine may also be used to treat itching in people with too much bile acid caused by a certain type of liver/bile duct disease (partial biliary obstruction). (kaiserpermanente.org)
  • Several data indicate that modulation of bile acid homeostasis has a good clinical effect in managing diabetes mellitus and the diarrhea from bile acid malabsorption.Cholestyramine is an anion binding resin that has a quaternary ammonium side chain that creates a localized, net positive charge. (herbaltransitions.com)
  • The point on C) is that statins jack up digoxin by 20%, so a provider reduced dosage at 80% of regular for statin plus a sequestrant (bile acid resin or ezetimibe) could be a good thing. (flashcardmachine.com)
  • The most commonly used options for pharmacologic treatment of dyslipidemia include bile acid-binding resins, HMG-CoA reductase inhibitors, nicotinic acid and fibric acid derivatives. (aafp.org)
  • To assess the reversibility of all parameter changes in patients who discontinue treatment after accelerated elimination procedure with cholestyramine or activated charcoal. (clinicaltrials.gov)
  • 13. A composition according to claim 1 wherein said binding reservoir is selected from the group consisting of activated charcoal, ion-exchange resin, immobilized antibody, silica, zeolite and molecular sieve. (google.co.uk)
  • tell your doctor and pharmacist if you are allergic to cholestyramine or any other drugs. (medlineplus.gov)
  • Your doctor may do blood tests or collect stool samples to test for bile acids or may simply prescribe cholestyramine if BAM is suspected to see if it lessens or resolves your diarrhea. (verywellhealth.com)
  • Strongly basic anion resins maintain their negative charge across a wide pH range, whereas weakly basic anion resins are neutralized at higher pH levels. (wikipedia.org)
  • For anion resins, regeneration typically involves treatment of the resin with a strongly basic solution, e.g. aqueous sodium hydroxide. (wikipedia.org)
  • While anion resins attract negatively charged ions, cation resins attract positively charged ions. (wikipedia.org)
  • This is not a list of all drugs or health problems that interact with cholestyramine resin. (drugs.com)
  • Cholestyramine or colestyramine is a bile acid sequestrant. (drugbank.ca)
  • To assess clinical efficacy and tolerability of cholestyramine therapy in patients with dyslipidemia and non-insulin-dependent diabetes mellitus (NIDDM). (nih.gov)
  • Two controlled clinical trials have examined the effects of cholestyramine monotherapy upon coronary atherosclerotic lesions using coronary arteriography. (nih.gov)
  • Two controlled clinical trials have examined the effects of cholestyramine for oral suspension monotherapy upon coronary atherosclerotic lesions using coronary arteriography. (nih.gov)
  • Cholestyramine resin is not absorbed from the digestive tract. (nih.gov)
  • changing your cholestyramine dose may change their effects. (medlineplus.gov)
  • Before using, be sure you know how to mix and measure the dose of cholestyramine resin. (drugs.com)
  • Cross-linked synthetic resin has been shown to cut wearrate and resultant osteolysis in full ball-and-socket joint arthroplasty. (torontofamilyhistory.org)
  • Constipation was the main side effect, and two patients dropped out of the study because of cholestyramine intolerance. (nih.gov)
  • Treat cholestyramine-induced constipation with? (brainscape.com)
  • Even though people have used clays - and Bentonite is one - with some success, cholestyramine is so much better that people would put up with the common side effects of constipation and some reflux. (mercola.com)
  • However, the use of cholestyramine has poor adherence with therapies, probably due to gastroenterological side effects especially constipation, and is not overly effective. (ispub.com)
  • Cholestyramine therapy for dyslipidemia in non-insulin-dependent diabetes mellitus. (nih.gov)