Chemicals and Drugs
Cholestanones
Cholestanones
CHOLESTANES substituted with any number of keto groups.

The conversion of cholest-5-en-3beta-ol into cholest-7-en-3beta-ol by the echinoderms Asterias rubens and Solaster papposus. (1/11)

1. The echinoderms Asterias rubens and Solaster papposus (Class Asteroidea) metabolize injected [4(-14)C]cholest-5-en-3beta-ol to produce labelled 5alpha-cholestan-3beta-ol and 5alpha-cholest-7-en-3beta-ol. 2. Conversion of 5alpha-[4(-14)C]cholestan-3beta-ol into 5alpha-cholest-7-en-3beta-ol was demonstrated in A. Rubens. 3. Incubations of A. rubens with [4(-14)C]cholest-4-en-3-one resulted in the production of labelled 5alpha-cholestan-3-one, 5alpha-cholestan-3beta-ol and 5alpha-cholest-7-en-3beta-ol. 4. [4(-14)C]Sitosterol was metabolized by A. rubens to give 5alpha-stigmastan-3beta-ol and 5alpha-stigmast-7-en-3beta-ol. 5. The significance of these results in relation to the presence of alpha7 sterols in starfish is discussed.  (+info)

A major ozonation product of cholesterol, 3beta-hydroxy-5-oxo-5,6-secocholestan-6-al, induces apoptosis in H9c2 cardiomyoblasts. (2/11)

Cholesterol, a major neutral lipid component of biological membranes and the lung epithelial lining fluids, is susceptible to oxidation by reactive oxygen and nitrogen species including ozone. The oxidation by ozone in biological environments results in the formation of 3beta-hydroxy-5-oxo-5,6-secocholestan-6-al (cholesterol secoaldehyde or CSeco, major product) along with some other minor products. Recently, CSeco has been implicated in the pathogenesis of atherosclerosis and Alzheimer's disease. In this communication, we report that CSeco induces cytotoxicity in H9c2 cardiomyoblasts with an IC(50) of 8.9+/-1.29 microM (n=6). The observed effect of CSeco at low micromolar concentrations retained several key features of apoptosis, such as changes in nuclear morphology, phosphatidylserine externalization, DNA fragmentation, and caspase 3/7 activity. Treatment of cardiomyocytes with 5 microM CSeco for 24h, for instance, resulted in 30.8+/-3.28% apoptotic and 1.8+/-1.11% of necrotic cells as against DMSO controls that only showed 1.3+/-0.33% of apoptosis and 1.6+/-0.67% of necrosis. In general, the loss of cellular viability paralleled the increased occurrence of apoptotic cells in various CSeco treatments. This study, for the first time, demonstrates the induction of apoptotic cell death in cardiomyocytes by a cholesterol ozonation product, implying a role for ozone in myocardial injury.  (+info)

Formation of cholesterol ozonolysis products in vitro and in vivo through a myeloperoxidase-dependent pathway. (3/11)

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Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells. (4/11)

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Anabolic effect of plant brassinosteroid. (5/11)

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Polyhydroxylated steroids from the bamboo coral Isis hippuris. (6/11)

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A phytooxysterol, 28-homobrassinolide modulates rat testicular steroidogenesis in normal and diabetic rats. (7/11)

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Cytotoxic effects of secosterols and their derivatives on several cultured cells. (8/11)

The cytotoxic effects of various oxysterols on several culture cells were examined. Ozonolysis products of cholesterol, secosterols (3beta-hydroxy-5-oxo-5,6-secocholestan-6-al) and its aldolization product (3beta-hydroxy-5beta-hydroxy-B-norcholestane-6beta-carboxaldehyde) and their keto alcohol and acid derivatives, were found to have potent cytotoxic activities, as compared with major endogenous oxysterols such as 5beta,6beta-epoxycholesterol, 7beta-hydroxycholesterol, 7-ketocholesterol, and 25-hydroxycholesterol. Secosterols might play important roles in tissue damage and inflammation-associated diseases.  (+info)

Studies on Cytotoxic Secondary Metabolities of the Formosan Gorgonian Sinularia gibberosa and Isis hippuris. - OpenThesisStudies on Cytotoxic Secondary Metabolities of the Formosan Gorgonian Sinularia gibberosa and Isis hippuris. - OpenThesis
In our continuing study on the chemical constituents of Taiwanese soft corals, the EtOAc extracts of a gorgonian coral Isis hippuris and a alcyonarian coral Sinularia gibberosa were investigated, respectively. Seven compounds, including 3£\,11£]-dihydroxy-24-methyl-22,25epoxy-5£\- furostan-18,20£]-lactone (1), 3-acetyl-2-deacetyl-22R-hippurin-1 (2), hippuristerone F (3), hippurin-1 (4), 22-epi-hippurin-1 (5), 3-acetyl-2- desacetyl-22-epi-hippurin-1 (6) and 2-desacetyl-22-epi-hippurin-1 (7) were isolated from I. hippuris. Three metabolites, 3£],11-dihydroxy-24- methylene-9,11-secocholest-5-en-9-one (8), 3£],11-dihydroxy-24-methyl-9, 11-secocholest-5-en- 9-one (9) and 3£]-hydroxy-11-acetoxy-24-methylene-9, 11-secocholest-5-en-9-one (10) were isolated from S. gibberosa. Among them, compounds 1¡V3, are new products. All metabolites 1¡V10 are steroids. The structures of 1¡V10 were determined by physical and spectral analysis, including IR, MS, 1D NMR (1H, 13C) and 2D NMR ( 1H-1H COSY, HMQC, ...
http://www.openthesis.org/documents/Studies-Cytotoxic-Secondary-Metabolities-Formosan-237808.html
3beta,11-dihydroxy-5beta,6beta-epoxy-24-methylene-9,11-secocholestan-9-one Summary Report | CureHunter3beta,11-dihydroxy-5beta,6beta-epoxy-24-methylene-9,11-secocholestan-9-one Summary Report | CureHunter
3beta,11-dihydroxy-5beta,6beta-epoxy-24-methylene-9,11-secocholestan-9-one: from the soft corals Sinularia lochmodes and Sinularia leptoclados; structure in first source
http://www.curehunter.com/public/keywordSummaryC511680-3beta-11-dihydroxy-5beta-6beta-epoxy-24-methylene-9-11-secocholestan-9-one.do
Title page for etd-0905111-173638Title page for etd-0905111-173638
Previous studies on the secondary metabolites of Formosan octocoral Isis hippuris were collected only at Green Island. In the course of our studies on secondary metabolites from marine organisms, the acetone-solubles of the Formosan octocoral Isis hippuris collected at Orchid Island has led to the isolation of eleven polyoxygenated steroids (1-11), along with two known compounds (12 and 13). The structures of these compounds were determined on the basis of their spectroscopic and physical data, including NMR, IR, MS, etc. The cytotoxicity against of A-549 (human lung epithelial carcinoma), HT-29 (human colon adenocarcinoma), and P-388 (mouse lymphocytic leukemia) cells, and anti-HCMV (human cytomegalovirus) activity of metabolites 1-13 were evaluated. Compounds 12 and 13 displayed cytotoxicity against P-388 cell line with ED50 values of 3.2 and 3.6 μg/mL, respectively. Compound 12 exhibited cytotoxicity against A-549 cell line with an ED50 value of 3.8 μg/mL. Compound 8 exhibit inhibitory ...
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0905111-173638
Improving Fruit Coloration, Quality Attributes, and Phenolics Content in Rainier and Bing Cherries by Gibberellic Acid...Improving Fruit Coloration, Quality Attributes, and Phenolics Content in Rainier and Bing Cherries by Gibberellic Acid...
The purpose of this work was to evaluate the potential of gibberellic acid (GA3) combined with homobrassinolide (HBR) treatment to improve fruit anthocyani
https://rd.springer.com/article/10.1007/s00344-019-10049-4?error=cookies_not_supported&code=8f3ea7fe-6d11-49b1-9377-2252c36cb286
IGF-1 LR3 - iSteroids.comIGF-1 LR3 - iSteroids.com
IGF-1 is a peptide roughly the same structure and size as insulin, or about 70 amino acids long. It belongs to the peptide family of substances identified as growth factors. It is a highly anabolic hormone released in the liver as well as in peripheral tissues such as skeletal muscle. In the body, IGF-1 is released in response to the presence of Human Growth Hormone (HGH). After intense resistance training, the body experiences a surge in GH and IGF, and this is one way that new muscle is built. Although GH is considered to be highly anabolic, in actuality, IGF-1 is suspected to be responsible for the primary anabolic activities of GH ...
http://www.isteroids.com/steroids/igf-1-lr3.html
NSP Free Form Singular Amino Acids (Pure) - NSP NutritionNSP Free Form Singular Amino Acids (Pure) - NSP Nutrition
For maximum muscle gains NSP Free Singular Amino Pure is an ultra-blend of all 17 Free L-form amino acids.. These protein substances have proven to be the most efficient source of anabolic activity, instantly absorbed into the blood stream creating a positive nitrogen balance and increasing muscle mass. Recommended use: take 4 to 7 capsules before and after training plus anytime during the day. Also use for quick energy.. This product is not intended to diagnose, treat, cure, or prevent any disease. Keep out of reach of children. Keep in a cool dry place free of excess heat. You have my personal guarantee this product does not contain anything artificial. All natural ingredients.. ...
http://nsp-nutrition.com/product/free-form-singular-amino-acids-pure/
Hair-relaxing composition comprising at least one base other than hydroxide - MALLE GERARDHair-relaxing composition comprising at least one base other than hydroxide - MALLE GERARD
The disclosure provides ready-to-use cosmetic compositions for relaxing keratin fibers in a cosmetically acceptable medium free of polyhydroxylated alkane, comprising, as a relaxing agent, a base not
http://www.freepatentsonline.com/y2005/0136016.html
The Efficacy of Etoposide on H9c2 Cardiomyoblasts Against Doxorubicin Induced CardiotoxicityThe Efficacy of Etoposide on H9c2 Cardiomyoblasts Against Doxorubicin Induced Cardiotoxicity
Background: Doxorubicin (DOX), a widely used anticancer drug, has been associated with cardiotoxicity. Recently, DOX-induced cardiotoxicity has been attributed to topoisomerase II (TOPII)-β expression and activity. In our study, we investigated the effect of inhibiting TOPII in attenuating the DOX induced cardiotoxicity. Method: H9c2 cardiomyoblasts were treated with 1 or 2 µM DOX (+/-) 1 µM ETO. Cardiotoxicity was assessed by examining cell viability using the MTT assay, hypertrophy of crystal violet stained cardiomyoblasts and ROS production. Results: DOX induced a dose dependent increase in cardiotoxicity as indicated by the significant reduction in cell viability (71.77 ± 9.25% 2 µM DOX vs. 100% control, P,0.05), ROS production and hypertrophy. Stimulation of H9c2 cardiomyoblasts with both 2 µM DOX and 1µM ETO did not show a significant difference in cell viability, ROS production or hypertrophy. Conclusion: DOX induced cardiotoxicity in H9c2 cardiomyoblasts was not exacerbated in the ...
http://qspace.qu.edu.qa/handle/10576/5441
Nkx2.5+ Cardiomyoblasts Contribute to Cardiomyogenesis in the Neonatal HeartNkx2.5+ Cardiomyoblasts Contribute to Cardiomyogenesis in the Neonatal Heart
During normal lifespan, the mammalian heart undergoes limited renewal of cardiomyocytes. While the exact mechanism for this renewal remains unclear, two possibilities have been proposed: differentiated myocyte replication and progenitor/immature cell differentiation. This study aimed to characterize a population of cardiomyocyte precursors in the neonatal heart and to determine their ... read more requirement for cardiac development. By tracking the expression of an embryonic Nkx2.5 cardiac enhancer, we identified cardiomyoblasts capable of differentiation into striated cardiomyocytes in vitro. Genome-wide expression profile of neonatal Nkx2.5+ cardiomyoblasts showed the absence of sarcomeric gene and the presence of cardiac transcription factors. To determine the lineage contribution of the Nkx2.5+ cardiomyoblasts, we generated a doxycycline suppressible Cre transgenic mouse under the regulation of the Nkx2.5 enhancer and showed that neonatal Nkx2.5+ cardiomyoblasts mature into cardiomyocytes ...
https://dspace.library.uu.nl/handle/1874/359281
YEUNGNAM UNIVERSITY: Tetracycline degradation by ozonation in the aqueous phase: Proposed degradation intermediates and pathwayYEUNGNAM UNIVERSITY: Tetracycline degradation by ozonation in the aqueous phase: Proposed degradation intermediates and pathway
During the ozonation of tetracycline (TC) in aqueous media at pHs 2.2 and 7.0, the effects of pH variations, protonation and dissociation of functional groups and variation in free radical exposure were investigated to elucidate the transformation pathway. Liquid chromatography-triple quadrupole mass spectrometry detected around 15 ozonation products, and uncovered their production and subsequent degradation patterns. During ozonation at pH 2.2, the TC degradation pathway was proposed on the basis of the structure, ozonation chemistry and mass spectrometry data of TC. Ozonation of TC at the C11a-C12 and C2-C3 double bonds, aromatic ring and amino group generated products of m/z 461, 477, 509 and 416, respectively. Further ozonation at the above mentioned sites gave products of m/z 432, 480, 448, 525 and 496. The removal of TOC reached a maximum of approximate to 40% after 2 h of ozonation, while TC was completely removed within 4-6 min at both pHs. The low TOC removal efficiency might be due to ...
http://ir.yu.ac.kr/handle/YU.REPOSITORY/23925
November 4, 2015 - mk-2866 CycleNovember 4, 2015 - mk-2866 Cycle
These agents have an unexpected and tissue-selective in-vivo activity for al androgenic and anabolic activity of a nonsteroidal ligand for the AR. These agents selectively act as partial agonists in some tissues while acting as full agonists in other tissues providing a a novel and unexpected means for eliciting tissue-selective androgenic or Ostarine For 12 Weeks Gtx-024 anabolic effects. Ostarine For 12 Weeks Gtx-024 in one embodiment Q is in the para position. In another embodiment X is O.. Ostarine is an orally active nonsteroidal SARM developed by GTx Inc. In the fitness industry users typically take Ostarine during bulking and recomposition phases. A compound that offers both fat loss muscle gain and strength gain benefits sounds extremely appealing to athletes looking to take their performance to the next-level. HPG axis suppression and elevated estradiol levels; both of which users report can be remedied with a 3-week PCT. PCT to mitigate further more serious side effects. Ligandrol is ...
http://mk2866cycle.com/2015/11/04/
supplements for athletessupplements for athletes
Forskolin is not only a popular supplement when it comes to training and sports, but its also a popular fat burner famous for its anabolic activities. It generally enhances fat loss by activating adenylate cyclase enzyme. This enzyme starts off a series of events including the activation of lipoprotein lipase that allows stored fat to be broken down to be used as a source of fuel. For quite some time people have been using supplement for weight loss and other training activities. Since our bodies love this supplement, they react well yielding a revitalized mind and a flatter stomach. It also stimulates the bodys metabolism so that it can burn more fat. This prevents the body from adding more fat and also melts away unwanted fat from the body.. It also raises your testosterone and thyroid hormone level thereby leading to an increase in fat burning and lean body mass. The fat in Forskolin activates kinase which plays an important role in the breakdown of the building blocks known as ...
http://www.racethundermountain.com/tag/supplements-for-athletes/
omega 3 benefitsomega 3 benefits
Forskolin is not only a popular supplement when it comes to training and sports, but its also a popular fat burner famous for its anabolic activities. It generally enhances fat loss by activating adenylate cyclase enzyme. This enzyme starts off a series of events including the activation of lipoprotein lipase that allows stored fat to be broken down to be used as a source of fuel. For quite some time people have been using supplement for weight loss and other training activities. Since our bodies love this supplement, they react well yielding a revitalized mind and a flatter stomach. It also stimulates the bodys metabolism so that it can burn more fat. This prevents the body from adding more fat and also melts away unwanted fat from the body.. It also raises your testosterone and thyroid hormone level thereby leading to an increase in fat burning and lean body mass. The fat in Forskolin activates kinase which plays an important role in the breakdown of the building blocks known as ...
http://www.racethundermountain.com/tag/omega-3-benefits/
What is Scarlet fever?What is Scarlet fever?
Scarlet fever is essentially a bacterial infection that leads to a typical pink-red rash. It is caused by an organism Streptococcus and is seen rarely in developed countries like United Kingdom these days.
https://www.news-medical.net/health/What-is-Scarlet-fever.aspx
Quercetin Reduces Inflammatory Responses in LPS-Stimulated Cardiomyoblasts - pdf descargarQuercetin Reduces Inflammatory Responses in LPS-Stimulated Cardiomyoblasts - pdf descargar
Quercetin Reduces Inflammatory Responses in LPS-Stimulated Cardiomyoblasts. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
http://libros.duhnnae.com/2017/jun9/149866578467-Quercetin-Reduces-Inflammatory-Responses-in-LPS-Stimulated-Cardiomyoblasts.php
UC/JEPS: Jepson Manual treatment for HIPPURIS vulgarisUC/JEPS: Jepson Manual treatment for HIPPURIS vulgaris
Flower inconspicuous, generally bisexual (or staminate below pistillate); calyx a minute rim at ovary top; petals 0; stamen 1, off-center on top of ovary; ovary inferior, chamber 1, style 1, off-center, ± = stamen, slender, generally in groove between anther sacs, ± entirely ...
http://ucjeps.berkeley.edu/cgi-bin/get_JM_treatment.pl?4515,4516,4517
Natures SterolsNatures Sterols
Healthy N Fit® NATURES STEROLS™ is a balanced, mega potency supplement that can aid in promoting anabolic activity. An incredible technological discovery for the competitive bodybuilder & athlete. ...
http://www.behealthynfit.com/SearchResults.asp?Cat=52
Natures SterolsNatures Sterols
Healthy N Fit International Inc. is an American corporation, founded and headquartered in New York, USA in 1976. Healthy N Fit specializes in manufacturing all natural health supplements, including protein powders, amino acids, spots nutrition, and vitamins. Healthy N Fits research and development has culminated into groundbreaking innovations and effective advanced nutritional technologies, which today are widely utilized throughout the sports nutrition industry; most notably being the first to bring egg white protein to the mass market.
http://www.behealthynfit.com/SearchResults.asp?Cat=79
Steroids Impair Immunotherapy For Mind Cancer - F.A.S.T Foundation LLCSteroids Impair Immunotherapy For Mind Cancer - F.A.S.T Foundation LLC
Invented in the summertime of 2001, D-Bol™ has rapidly become the most well-liked oral anabolic obtainable due to reviews of extraordinarily dramatic muscle strength and dimension features. D-Bol™ has a particular formulation containing methadrostenol that will exert a pronounced ergogenic action in the body after oral administration. D-Bol™ tablets lack an altered C-17th carbon configuration thus making it utterly secure with little or no hepatotoxicity. Due to this explicit construction, there seems to be a longer half-life of anabolic activity present in trained skeletal muscle. Invented in the summer of 2001, D-Bol™ has become the most popular oral anabolic available due to reviews of extremely dramatic muscle power and size gains. The dose was 3 times what many bodybuilders would use and the treatment period was considerably longer. Since oxymetholone was brought back to the U.S. early in 1998, we are going to see how effective it is and in addition see whether or not there truly ...
https://www.fastspeech.org/steroids-impair-immunotherapy-for-mind-cancer/
Painkiller ProductsPainkiller Products
Trenbolone Hexa hydro chloro benzyl carbonate 76.5 mg/ ml is a very potent androgen with strong anabolic activity. It is well suited for the rapid buildup of strength and muscle mass and does not convert to estrogen. This is indeed a very unique compound since mass drugs, almost as a rule, will aromatize heavily, extremely potent mass/strength drug. There is no noticeable water retention, so the mass gained during a cycle of Tren HBC will be very hard and defined (providing fat levels).. ...
https://painkillermedicines.com/product_details/get_product_details/48/79
Orions Arm - Encyclopedia Galactica - BiochemistryOrions Arm - Encyclopedia Galactica - Biochemistry
Polyhydroxylated compounds such as sugars, sugar alcohols and sugar acids. They are components of nucleic acids, cell membranes and also act as energy sources. Polyols are vital to all known terragen and most xenobiont carbon-based lifeforms. They are occasionally present in some meteors, comets, and Kuiper bodies, in amounts comparable to amino acids. Extraterrestrial processes including photolysis and formaldehyde chemistry account for their origin. It has been shown that these compounds seed EoGaian worlds through asteroid and comet impacts, where they play a role in the origin of life ...
http://orionsarm.com/eg-topic/45b18ad53a990
PPT - Carbohydrates PowerPoint Presentation - ID:3348426PPT - Carbohydrates PowerPoint Presentation - ID:3348426
Carbohydrates. Carbohydrate Broad class of polyhydroxylated aldehydes and ketones commonly called sugars Synthesized by green plants during photosynthesis Name derived from glucose Glucose was the first simple carbohydrate obtained in pure form Slideshow 3348426 by larue
http://www.slideserve.com/larue/carbohydrates
Current Clinical Trials of FlavopiridolCurrent Clinical Trials of Flavopiridol
Flavopiridol [2-(2-chlorophenyl 5 ,7-dihydroxy-8-[cis-(3-hydroxy-1-methyl-4-piperidinyl)-4H-1-benzopyran-4-one, hydrochloride] is a semisynthetic flavone with a novel structure compared with that of polyhydroxylated flavones, such as quercetin and genistein.[1] It is derived from rohitukine, an alkaloid isolated from the stem bark of Dysoxylum binectariferum, a plant indigenous to India.[2] Originally synthesized and supplied by Hoechst India Limited, flavopiridol is provided to the Division of Cancer Treatment and Diagnosis of the National Cancer Institute (NCI) by Aventis Pharmaceuticals, Inc.
https://www.cancernetwork.com/view/current-clinical-trials-flavopiridol
ASTERIAS RUBENS - A Text-Book of Materia Medica. By Pr. Allen Corson CowperthwaiteASTERIAS RUBENS - A Text-Book of Materia Medica. By Pr. Allen Corson Cowperthwaite
Petroz.. Acts upon the cerebro-spinal system, giving readily and often in profusion symptoms indicating disturbance of function, but it never goes on to alteration of tissue, rarely even to the earliest indications thereof.. Its general tendency is to produce irritation and congestion of venous parts, never reaching true inflammation.. Characteristic symptoms.. Mind.- (Asterias rubens). Very sensitive ; weeping ; melancholy ; depressed ; irritable.. Head.- (Asterias rubens). Vertigo.. Heat of the head, as if surrounded by hot air.. Sense of fullness, and rush of blood to the head.. Throbbing in the head.. Sensation as if the brain were receiving shocks from an electric battery ; head felt as if bursting ; consciousness almost extinct ; hard pulse, and throbbing of right carotid. (Bell.). Pressive and lancinating pains in temples and elsewhere.. Eyes.- (Asterias rubens). Eyes bloodshot, and feel hot. (Acon., Bell.). Fatigued look ; light fatigues the eyes.. Face.- (Asterias rubens). Redness of ...
http://homeoint.org/seror/cowperthwaite/aster.htm
ReferanserReferanser
Albayrak, S. 1996. Echinoderm fauna of the Bosporus (Türkiye). Oebalia 22: 25-32.. Anderson, R. C. & Shimek, R. L. 1993. A note on the feeding habits of some uncommon sea stars. Zoobiology 12: 499-503.. Anger, K., Rogal, U., Schriever, G. & Valentin C. 1977. In-situ investigations on the echinoderm Asterias rubens as a predator of soft-bottom communities in the western Baltic Sea. Helgoländer wissenschaftliche Meeresuntersuchungen 29: 439-459.. Anisimova, N.A. & Cochrane, S.J. 2003. An annotated checklist of the echinoderms of the Svalbard and Franz Josef Land archipelagos and adjacent waters. Sarsia 88: 113-135.. Anonym. 2007. Survey report from the joint Norwegian/Russian ecosystem Survey in the Barents Sea August-October 2006 (vol.2). IMR/PINRO Joint Report Series, No. 1/2007.. Asbjørnsen, P.C. 1853. Bidrag til Christianiafjordens Littoralfauna. I. Mollusker. Christiania. Nytt Mag. Naturvid. 7 H 4.. Asbjørnsen, P.C. 1856. Brisinga endecacnemos. I: Sars, G.O., Koren, J. & Danielssen, D.C. ...
https://artsdatabanken.no/Pages/229600/Referanser?Key=1440398009
ReferanserReferanser
Albayrak, S. 1996. Echinoderm fauna of the Bosporus (Türkiye). Oebalia 22: 25-32.. Anderson, R. C. & Shimek, R. L. 1993. A note on the feeding habits of some uncommon sea stars. Zoobiology 12: 499-503.. Anger, K., Rogal, U., Schriever, G. & Valentin C. 1977. In-situ investigations on the echinoderm Asterias rubens as a predator of soft-bottom communities in the western Baltic Sea. Helgoländer wissenschaftliche Meeresuntersuchungen 29: 439-459.. Anisimova, N.A. & Cochrane, S.J. 2003. An annotated checklist of the echinoderms of the Svalbard and Franz Josef Land archipelagos and adjacent waters. Sarsia 88: 113-135.. Anonym. 2007. Survey report from the joint Norwegian/Russian ecosystem Survey in the Barents Sea August-October 2006 (vol.2). IMR/PINRO Joint Report Series, No. 1/2007.. Asbjørnsen, P.C. 1853. Bidrag til Christianiafjordens Littoralfauna. I. Mollusker. Christiania. Nytt Mag. Naturvid. 7 H 4.. Asbjørnsen, P.C. 1856. Brisinga endecacnemos. I: Sars, G.O., Koren, J. & Danielssen, D.C. ...
https://www.artsdatabanken.no/Pages/229600/Referanser
Hippuris vulgarisHippuris vulgaris
In muddy pools and edges of lochs. Scarce, but more frequent in Argyll.. Aerial part of stem up to c 20 cm high, submerged stems can be much longer.. ID: Leaves in whorls of c 6-12, flat, linear, blue-green, smooth. Stem round in cross-section.. Other features: Stems often red. Flowers tiny, green, in leaf-axils, often absent. Some submerged stems can be flaccid, horizontal and long-trailing, with leaf-whorls more spaced. Others grow upwards until they break the water surface and become aerial stems. Only the aerial stems bear flowers.. Horsetails, which are often called Marestails (especially Field Horsetail), look superficially similar, but have branches (not leaves) in whorls, angular, not flat, and with sheaths along their length. Bedstraw species such as Goosegrass have whorled leaves but these are dark green without the smooth shiny look of Marestail, and the stems are four-angled ...
http://plant-identification.co.uk/skye/hippuridaceae/hippuris-vulgaris.htm
SARMS Effect on Sex Drive and Sperm - Proven PeptidesProven PeptidesSARMS Effect on Sex Drive and Sperm - Proven PeptidesProven Peptides
Overall, SARMs do not affect sex drive or sperm count.. As one of the distasteful side effects of steroids or other strong testosterone-enhancers, the negative effects of reduced sex drive and sperm count were on the top of the list when making SARMs. The producers of SARMs wanted to design a supplement that gave all the great benefits of steroids, while still specifically promoting full anabolic activity muscle and bone.. All this is to say that SARMs have been specifically designed to avoid those side effects of reduced sperm count or other sexual side effects with could lead to problems infertility. Plus, they are showing to have minimal effects on the prostate in general, which cant be said for most other steroids or prohormones. By avoiding high concentrations of anabolic steroids, scientists think SARMs will more effectively dodge the risk of throwing hormones wildly off balance.. In fact, SARMs are giving some surprising results during testing phases that look promising. Some SARMs, such ...
https://provenpeptides.com/sarms-effect-on-sex-drive-and-sperm/
Breast MusclesBreast Muscles
Astemizole - increased risk of arrhythmia; • Indomethacin and other does not exceed 50-60 mg per day. Dermatological reactions: possible (Halotestin) Fluoxymesterone (Halotestin) - is a steroid oral form of application, showing a powerful androgenic and relatively low anabolic activity. If this does not happen often the 15th) ovulation should occur. Although it is worth remembering that often produced precisely in the form of tablets), most prefer the injection enanthate, which is more powerful, evenly acting and does not require frequent administration of the drug. No specific methods of treatment headaches, nervousness, agitation, aggressiveness, increased blood pressure and symptoms from the heart. These effects include the growth and maturation of the prostate gland more potent androgen receptor agonist (activator) than DHT. Useful properties and why it is used in bodybuilding Without going into the anastrozole is an antiestrogenic drug designed to treat common breast cancer in women ...
http://www.islssl-us.org/?p=3713
Mesterolone For Sale | Mesterolone 25 mg | Proviron For Sale | IronDaddyMesterolone For Sale | Mesterolone 25 mg | Proviron For Sale | IronDaddy
Mesterolone is a strong androgen with only a pretty weak level of anabolic activity and very often, this product is being called Proviron since is a...
https://irondaddy.to/product-category/post-cycle-therapy/mesterolone/
The mTOR Signaling Pathway and Regulation of Pancreatic Function | PancreapediaThe mTOR Signaling Pathway and Regulation of Pancreatic Function | Pancreapedia
Another major signal regulating TORC1 activity is the abundance of amino acids which tells the organism to undergo anabolic activity (1, 22). Conversely the absence of adequate amino acids is a stress which leads to the shutting down of biosynthetic pathways and the induction of autophagy. The major amino acids sensed are the branched chain amino acids, especially leucine, as well as arginine and glutamine. Amino acid sensing involves recruitment of TORC1 from cytoplasm to lysosomes where it interacts with proteins including the Rag GTPases (23), a protein complex termed the ragulator (33), amino acid transporters (17) and the lysosomal vacuolar ATPase (12). In the presence of amino acids, Rheb which is also localized on the lysosome, is activated and in turn activates TORC1. Furthermore, amino acids are necessary for almost all other mechanisms activating TORC1. Low oxygen or low glucose levels prevent TORC1 signaling through AMP Kinase and reduce the activity of the proteins REDD and BMIP3 ...
https://pancreapedia.org/molecules/mtor-signaling-pathway-and-regulation-of-pancreatic-function
Édouard Manet | Fishing | The MetÉdouard Manet | Fishing | The Met
Patterned after elements in landscapes by Peter Paul Rubens, the present painting gives currency to Delacroixs recommendation to Manet: Look at Rubens, draw inspiration from Rubens, copy Rubens. Rubens was God
https://www.metmuseum.org/art/collection/search/436951
Tag: phenylpropanoids | Highlight HEALTHTag: phenylpropanoids | Highlight HEALTH
Polyphenolic compounds (meaning the presence of more than one phenol group per molecule), often referred to as polyphenols, are plant-derived polyhydroxylated (meaning has more than one hydroxyl (OH), or alcohol, group attached) phytochemicals. Polyphenols are divided into three classes and include tannins, phenylpropanoids and flavonoids. ...
http://www.highlighthealth.com/tag/phenylpropanoids/
Dr. Jami Rubens, Radiology, Weston, MADr. Jami Rubens, Radiology, Weston, MA
Connect with Dr. Jami Rubens, Radiology, Weston, MA. Video chat, send a message, ask a text question, or make a virtual appointment on the doctors Virtual Practice on HealthTap.
https://www.healthtap.com/experts/36534944-dr-jami-rubens
Capriati megszerette a Ferrarit, Barrichello ki br ndult bel leCapriati megszerette a Ferrarit, Barrichello ki br ndult bel le
Jennifer Capriati a Key Biscayne-i tenisztorn n Ferrari-mezben p f lte a labd t, Rubens Barrichello Sao Paul ban panaszkodott a v r s k Forma-1-es
https://www.origo.hu/sport/f-1/20020328capriati.html
Brassinosteroids and gibberellic acid: effects on in vitro pollen germination in grapevine | OENO OneBrassinosteroids and gibberellic acid: effects on in vitro pollen germination in grapevine | OENO One
In this study, the response of pollens obtained from inflorescences of table grape cultivars Italia and Cardinal to different plant growth regulators added to the medium in Petri dishes was evaluated. Statistical analysis showed that pollen germination of cv. Italia was not influenced (p≥0.05) by the plant growth regulators (Table 1). Pollens not treated with any plant growth regulators (control) showed 26.08% germination, while the highest ratio was obtained from 0.001 mg L-1 EBR treatment (44.40%). The lowest percentage of germination was obtained from the application of 0.1 mg L-1 HBR (17.85%). Although no significant differences were observed, it was seen in the mean values of the applications that as the amount of GA3 in the combination treatments increased, the mean ratio of pollen germination slightly decreased. In addition, homobrassinolide yielded higher germination compared to epibrassinolide. Pollens of cv. Cardinal, on the other hand, responded significantly (p≤0.01) ...
https://oeno-one.eu/article/view/1862
Research Publications- Respiratory System | Respiratory MucosaResearch Publications- Respiratory System | Respiratory Mucosa
Activation of transcription factor IL-6 (NF-IL-6) and nuclear factor-kappaB (NF-kappaB) by lipid ozonation products is crucial to interleukin-8 gene expression in human airway epithelial cells. Ozone (O(3)) is a major component of smog and an inhaled toxicant to the lung. O(3) rapidly reacts with the airway epithelial cell membrane phospholipids to... ...
http://molecularstation.com/files/research/respiratory-system/respiratory-mucosa/
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https://eventorum.puc.edu/usarx/cialis-levitra-combination/82/
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HKU Scholars Hub: 3,3,4,5,5-pentahydroxy-trans-stilbene, a resveratrol derivative, induces apoptosis in colorectal carcinoma...HKU Scholars Hub: 3,3,4,5,5-pentahydroxy-trans-stilbene, a resveratrol derivative, induces apoptosis in colorectal carcinoma...
Resveratrol exhibits anti-tumor properties against different types of cancer. In this study, several polyhydroxylated resveratrol derivatives were prepared with the aim of discovering new leading compounds with clinical potential for human colon cancer chemotherapy. Among these compounds, 3,3,4,5,5-pentahydroxy-. trans-stilbene (PHS) displayed the most potent cytotoxicity and triggered apoptosis in HT-29 cells as evidenced by increased poly(ADP-ribose) polymerase (PARP) cleavage, elevated levels of cytoplasmic nucleosomes and DNA fragmentation. Further mechanistic analysis revealed that PHS-induced apoptosis was caspase-dependent and mediated by its pro-oxidative action through up-regulation of reactive oxidative species generation and depletion of intracellular glutathione. © 2010 Elsevier B.V ...
http://hub.hku.hk/handle/10722/179191
Tag: tannins | Highlight HEALTHTag: tannins | Highlight HEALTH
Polyphenolic compounds (meaning the presence of more than one phenol group per molecule), often referred to as polyphenols, are plant-derived polyhydroxylated (meaning has more than one hydroxyl (OH), or alcohol, group attached) phytochemicals. Polyphenols are divided into three classes and include tannins, phenylpropanoids and flavonoids. ...
http://www.highlighthealth.com/tag/tannins/
Chris Rubens & Greg Hill - The Curve of Time - BLISTERChris Rubens & Greg Hill - The Curve of Time - BLISTER
Chris Rubens and Greg Hill recount here their efforts to decrease their personal impact on the environment. Its definitely worth a watch, and will hopefully get each of us thinking and acting in new ways.
https://blisterreview.com/videos/chris-rubens-greg-hill-the-curve-of-time
Penicillium rubens Biourge ATCC ® 11709™Penicillium rubens Biourge ATCC ® 11709™
Penicillium rubens ATCC ® 11709™ Designation: Wis. 49-133 [NRRL 2272] Application: Produces penicillin Transformations of uleine Pharmaceutical and Personal Care
https://www.atcc.org/Products/Quality_Control_Strains/Pharmaceutical_and_Personal_Care/11709.aspx?p=1&rel=%7B0%7D&slp=1
National Gallery in London presents works by Flemish master RubensNational Gallery in London presents works by Flemish master Rubens
Rubens: A Master in the Making, which traces the first 15 years of the artists career, includes a drawing which is on display for the first time. The exhib...
https://english.pravda.ru/news/science/69243-n/
Brassinosteroids | REACHBrassinosteroids | REACH
This graph shows the total number of publications written about Brassinosteroids by people in this website by year, and whether Brassinosteroids was a major or minor topic of these publications ...
https://reach.sickkids.ca/display/13173
PQR | 14alpha-ethyl-5alpha-cholest-7-ene-3beta,15alpha-diolPQR | 14alpha-ethyl-5alpha-cholest-7-ene-3beta,15alpha-diol
You are viewing an interactive 3D depiction of the molecule 14alpha-ethyl-5alpha-cholest-7-ene-3beta,15alpha-diol (C29H50O2) from the PQR.
http://pqr.pitt.edu/mol/QGLIKDSBWIUDFT-YWPGFNJJSA-N
Eicosapentaenoic acid protects against palmitate induced cell death of h9c2 cardiomyoblastsEicosapentaenoic acid protects against palmitate induced cell death of h9c2 cardiomyoblasts
Intracellular accumulation of fatty acid metabolites in non-adipose tissues has been proposed to play an important role in the pathogenesis of diabetes mellitus. Moreover, lipotoxicity may contribute to cell death and cardiac dysfunction. Evidence is emerging that saturated fatty acids induce cell death through apoptosis and this effect is specific for palmitate and stearate. On the other hand, n-3 polyunsaturated fatty acids (PUFAs) have been implicated in the protection against cardiovascular diseases, cardiac ischemic damage and myocardial dysfunction. In the present study we show- that supplementation with the n-3 PUFA- eicosapentaenoic acid (EPA)- to culture medium of H9c2 rat cardiomyoblasts protects cells against palmitate-induced apoptosis. Experiments were performed by using H9c2 rat ventricular cardiomyoblasts. Apoptosis was detected by trypan blue exclusion, MTT or caspase activity assays. Gene expression was investigated by Real Time PCR. Signal transduction pathways were ...
https://cris.unibo.it/handle/11585/103376
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https://www.nutritionexpress.com/protein/amino+acids/combinations/healthy+n+fit+anabolic+amino+10000+180+tablets.aspx
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Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase | PNASStructural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase | PNAS
The central role of cyclin-dependent kinases (CDKs) in cell cycle regulation makes them a promising target for studying inhibitory molecules that can modify the degree of cell proliferation. The discovery of specific inhibitors of CDKs such as polyhydroxylated flavones has opened the way to investigation and design of antimitotic compounds. A novel flavone, (-)-cis-5,7-dihydroxyphenyl-8-[4-(3-hydroxy-1-methyl)piperidinyl] -4H-1-benzopyran-4-one hydrochloride hemihydrate (L868276), is a potent inhibitor of CDKs. A chlorinated form, flavopiridol, is currently in phase I clinical trials as a drug against breast tumors. We determined the crystal structure of a complex between CDK2 and L868276 at 2.33 angstroms resolution and refined to an Rfactor 20.3%. The aromatic portion of the inhibitor binds to the adenine-binding pocket of CDK2, and the position of the phenyl group of the inhibitor enables the inhibitor to make contacts with the enzyme not observed in the ATP complex structure. The analysis of ...
https://www.pnas.org/content/93/7/2735?ijkey=b86da83b7ae4c3f179cf3f9b644ef62c975ff0e5&keytype2=tf_ipsecsha
Pc13g06570 - Pc13g06570 protein - Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) -...Pc13g06570 - Pc13g06570 protein - Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) -...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
https://www.uniprot.org/uniprot/B6H3D1
Pc22g15750 - Pc22g15750 protein - Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) -...Pc22g15750 - Pc22g15750 protein - Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) -...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
https://www.uniprot.org/uniprot/B6HQB3
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Judgement of Paris :: Art History LibraryJudgement of Paris :: Art History Library
Mythological Scene showing the Judgement of Paris with three nude figuere to the left and Paris on the left offering his golden Apple. International Baroque style typical to Rubens in style with sweeping diagonal lines, bold composition, rich colors and textures and a grand style ...
http://contentdm.lib.byu.edu/cdm/ref/collection/artlibrary/id/3595/
List of MeSH codes (D04)List of MeSH codes (D04)
... cholestanones MeSH D04.808.247.222 - cholestenes MeSH D04.808.247.222.159 - cholecalciferol MeSH D04.808.247.222.159.478 - ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D04)
List of MeSH codes (D04) - WikipediaList of MeSH codes (D04) - Wikipedia
... cholestanones MeSH D04.808.247.222 - cholestenes MeSH D04.808.247.222.159 - cholecalciferol MeSH D04.808.247.222.159.478 - ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D04)
AU688994B2 - Combination method for acne treatment - Google PatentsAU688994B2 - Combination method for acne treatment - Google Patents
Combination method of treating acne using 4-AZA-5α-cholestan-ones and 4-AZA-5α-androstan-ones as selective 5α-reductase ...
https://patents.google.com/patent/AU688994B2/en
MH DELETED MN ADDED MNMH DELETED MN ADDED MN
Cholestanones D4.808.247.125 D4.210.500.247.125 Cholestenes D4.808.247.222 D4.210.500.247.222 Cholestenones D4.808.247.222.265 ...
http://decs2019.bvsalud.org/I/mnchg2017.txt
Sterols | Profiles RNSSterols | Profiles RNS
Teplyuk NM, Zhang Y, Lou Y, Hawse JR, Hassan MQ, Teplyuk VI, Pratap J, Galindo M, Stein JL, Stein GS, Lian JB, van Wijnen AJ. The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts. Mol Endocrinol. 2009 Jun; 23(6):849-61 ...
https://profiles.rush.edu/display/14232
Search | Global Index MedicusSearch | Global Index Medicus
Antioxidants/metabolism , Cadmium/toxicity , Cholestanones/pharmacology , Oxidative Stress/drug effects , Plant Growth ...
https://search.bvsalud.org/gim/?lang=en&q=au:Sharma,+Indu
Regiocontrolled Coupling of (π-Allylic)palladium Complexes with Organozirconium Species<...Regiocontrolled Coupling of (π-Allylic)palladium Complexes with Organozirconium Species<...
TY - JOUR. T1 - Regiocontrolled Coupling of (π-Allylic)palladium Complexes with Organozirconium Species. AU - Temple, James S.. AU - Riediker, Martin. AU - Schwartz, Jeffrey. PY - 1982/1/1. Y1 - 1982/1/1. N2 - A carbon-carbon bond-forming reaction has been developed involving coupling between an alkenylzirconium(IV) complex, prepared by hydrozirconation of the corresponding terminal acetylene, and (η3-allylic)palladium chloride dimers, prepared from olefins, to give 1,4 dienes. A stereospecific synthesis of 20(R)-cholestan-3-one is described. Bis(η5-cyclo-pentadienyl)chloro(4′-methylpent-1′-en-1′-yl)zirconium reacts with di-μ-chloro-bis[η3-16,17,20-(3-oxopregn-17(20)(Z)-en-16-yl ethylene ketal)]dipalladium in the presence of maleic anhydride. A mixture is obtained consisting of 1,4 dienes produced by addition of the alkenyl group to either the C(20) or C(16) terminus, respectively, of the allylic system. Hydrogenation of the C(20)-coupled product and deketalization yielded ...
https://collaborate.princeton.edu/en/publications/regiocontrolled-coupling-of-%CF%80-allylicpalladium-complexes-with-org
cholestanolcholestanol
cholestanones*steroid hydroxylases*lanosterol*squalene*hydroxycholesterols*germ free life*stigmasterol*cholestadienols*tomatine ...
http://www.labome.org/topics/polycyclic/fused/steroids/cholestanes/cholestanols/cholestanol-11816.html
Brassinosteroids. Medical search. DefinitionsBrassinosteroids. Medical search. Definitions
There are three primary classes: auxins, cytokinins, and gibberellins.Cholestanones: CHOLESTANES substituted with any number of ... BrassinosteroidsSteroids, HeterocyclicCholestanolsPlant Growth RegulatorsCholestanonesPhytosterolsArabidopsis Proteins ... BrassinosteroidsSteroids, HeterocyclicCholestanolsPlant Growth RegulatorsCholestanonesPhytosterolsArabidopsis Proteins ...
https://lookformedical.com/en/definitions/brassinosteroids

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