Salts and esters of CHOLIC ACID.

Acute effects of intravenous infusion of ApoA1/phosphatidylcholine discs on plasma lipoproteins in humans. (1/61)

To investigate the metabolism of nascent HDLs, apoA1/phosphatidylcholine (apoA1/PC) discs were infused IV over 4 hours into 7 healthy men. Plasma total apoA1 and phospholipid (PL) concentrations increased during the infusions. The rise in plasma apoA1 was greatest in small prebeta-migrating particles not present in the infusate. Total HDL unesterified cholesterol (UC) also increased simultaneously. After stopping the infusion, the concentrations of apoA1, PL, HDL UC, and small prebeta HDLs decreased, whereas those of HDL cholesteryl ester (CE) and large alpha-migrating apoA1 containing HDLs increased. ApoB-containing lipoproteins became enriched in CEs. Addition of apoA1/PC discs to whole blood at 37 degrees C in vitro also generated small prebeta HDLs, but did not augment the transfer of UC from erythrocytes to plasma. We conclude that the disc infusions increased the intravascular production of small prebeta HDLs in vivo, and that this was associated with an increase in the efflux and esterification of UC derived from fixed tissues. The extent to which the increase in tissue cholesterol efflux was dependent on that in prebeta HDL production could not be determined. Infusion of discs also reduced the plasma apoB and apoA2 concentrations, and increased plasma triglycerides and apoC3. Thus, nascent HDL secretion may have a significant impact on prebeta HDL production, reverse cholesterol transport and lipoprotein metabolism in humans.  (+info)

mrp, a multigene, multifunctional locus in Bacillus subtilis with roles in resistance to cholate and to Na+ and in pH homeostasis. (2/61)

A 5.9-kb region of the Bacillus subtilis chromosome is transcribed as a single transcript that is predicted to encode seven membrane-spanning proteins. Homologues of the first gene of this operon, for which the designation mrp (multiple resistance and pH adaptation) is proposed here, have been suggested to encode an Na+/H+ antiporter or a K+/H+ antiporter. In the present studies of the B. subtilis mrp operon, both polar and nonpolar mutations in mrpA were generated. Growth of these mutants was completely inhibited by concentrations of added Na+ as low as 0.3 M at pH 7.0 and 0.03 M at pH 8.3; there was no comparable inhibition by added K+. A null mutant that was constructed by full replacement of the mrp operon was even more Na+ sensitive. A double mutant with mutations in both mrpA and the multifunctional antiporter-encoding tetA(L) gene was no more sensitive than the mrpA mutants to Na+, consistent with a major role for mrpA in Na+ resistance. Expression of mrpA from an inducible promoter, upon insertion into the amyE locus, restored significant Na+ resistance in both the polar and nonpolar mrpA mutants but did not restore resistance in the null mutant. The mrpA disruption also resulted in an impairment of cytoplasmic pH regulation upon a sudden shift in external pH from 7.5 to 8.5 in the presence of Na+ and, to some extent, K+ in the range from 10 to 25 mM. By contrast, the mrpA tetA(L) double mutant, like the tetA(L) single mutant, completely lost its capacity for both Na+- and K+-dependent cytoplasmic pH regulation upon this kind of shift at cation concentrations ranging from 10 to 100 mM; thus, tetA(L) has a more pronounced involvement than mrpA in pH regulation. Measurements of Na+ efflux from the wild-type strain, the nonpolar mrpA mutant, and the complemented mutant indicated that inducible expression of mrpA increased the rate of protonophore- and cyanide-sensitive Na+ efflux over that in the wild-type in cells preloaded with 5 mM Na+. The mrpA and null mutants showed no such efflux in that concentration range. This is consistent with MrpA encoding a secondary, proton motive force-energized Na+/H+ antiporter. Studies of a polar mutant that leads to loss of mrpFG and its complementation in trans by mrpF or mrpFG support a role for MrpF as an efflux system for Na+ and cholate. Part of the Na+ efflux capacity of the whole mrp operon products is attributable to mrpF. Neither mrpF nor mrpFG expression in trans enhanced the cholate or Na+ resistance of the null mutant. Thus, one or more other mrp gene products must be present, but not at stoichiometric levels, for stability, assembly, or function of both MrpF and MrpA expressed in trans. Also, phenotypic differences among the mrp mutants suggest that functions in addition to Na+ and cholate resistance and pH homeostasis will be found among the remaining mrp genes.  (+info)

Substrates of multidrug resistance-associated proteins block the cystic fibrosis transmembrane conductance regulator chloride channel. (3/61)

1. The effects of physiological substrates of multidrug resistance-associated proteins (MRPs) on cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel currents were examined using patch clamp recording from CFTR-transfected mammalian cell lines. 2. Two MRP substrates, taurolithocholate-3-sulphate (TLCS) and beta-estradiol 17-(beta-D-glucuronide) (E217betaG) caused a voltage-dependent block of macroscopic CFTR Cl- currents when applied to the intracellular face of excised membrane patches, with mean apparent dissociation constants (KDs) of 96+/-10 and 563+/-103 microM (at 0 mV) respectively. The unconjugated bile salts taurocholate and cholate were also effective CFTR channel blockers under these conditions, with KDs of 453+/-44 and 3760+/-710 microM (at 0 mV) respectively. 3. Reducing the extracellular Cl- concentration from 154 to 20 mM decreased the KD for block intracellular TLCS to 54+/-1 microM, and also significantly reduced the voltage dependence of block, by suggesting that TLCS blocks Cl- permeation through CFTR by binding within the channel pore. 4. Intracellular TLCS reduced the apparent amplitude of CFTR single channel currents, suggesting that the duration of block is very fast compared to the gating of the channel. 5. The apparent affinity of block by TLCs is comparable to that of other well-known CFTR channel blockers, suggesting that MRP substrates may comprise a novel class of probes of the CFTR channel pore. 6. These results also suggest that the related proteins CFTR and MRP may share a structurally similar anion binding site at the cytoplasmic face of the membrane.  (+info)

Antimicrobial activities of amine- and guanidine-functionalized cholic acid derivatives. (4/61)

Compounds in a series of cholic acid derivatives, designed to mimic the activities of polymyxin B and its derivatives, act as both potent antibiotics and effective permeabilizers of the outer membranes of gram-negative bacteria. Some of these compounds rival polymyxin B in antibacterial activity against gram-negative bacteria and are also very active against gram-positive organisms. Other compounds interact synergistically with hydrophobic antibiotics to inhibit bacterial growth.  (+info)

Uptake of bromosulfophthalein via SO2-4/OH- exchange increases the K+ conductance of rat hepatocytes. (5/61)

In confluent primary cultures of rat hepatocytes, micromolar concentrations of bromosulfophthalein (BSP) lead to a sizeable hyperpolarization of membrane voltage. The effect is a saturable function of BSP concentration yielding an apparent value of 226 micromol/l and a Vmax of -10.3 mV. The BSP-induced membrane hyperpolarization is inhibited by the K+ channel blocker Ba2+, and in cable-analysis and ion-substitution experiments it becomes evident that the effect is due to a significant increase in cell membrane K+ conductance. Voltage changes were attenuated by the simultaneous administration of SO2-4, succinate, and cholate (cis-inhibition) and increased after preincubation with SO2-4 and succinate (trans-stimulation), suggesting that the effect occurs via BSP uptake through the known SO2-4/OH- exchanger. Microfluorometric measurements reveal that BSP-induced activation of K+ conductance is not mediated by changes in cell pH, cell Ca2+, or cell volume. It is concluded that K+ channel activation by BSP (as well as by DIDS and indocyanine green) may reflect a physiological mechanism linking the sinusoidal uptake of certain anions to their electrogenic canalicular secretion.  (+info)

Hyperlipidemia and atherosclerotic lesion development in LDL receptor-deficient mice fed defined semipurified diets with and without cholate. (6/61)

Past studies of atherosclerosis in mice have used chow-based diets supplemented with cholesterol, lipid, and sodium cholate to overcome species resistance to lesion formation. Similar diets have been routinely used in studies with LDL receptor-deficient (LDLR(-/-)) mice. The nonphysiological nature and potential toxicity of cholate-containing diets have led to speculation that atherogenesis in these mice may not accurately reflect the human disease process. We have designed a semipurified AIN-76A-based diet that can be fed in powdered, pelleted, or liquid form and manipulated for the precise evaluation of diet-genetic interactions in murine atherosclerosis. LDLR(-/-) mice were randomly assigned among 4 diets (n=6/diet) as follows: 1, control, 10% kcal lipid; 2, high fat (40% kcal), moderate cholesterol (0.5% by weight); 3, high fat, high cholesterol (1.25% by weight); and 4, high fat, high cholesterol, and 0.5% (wt/wt) sodium cholate. Fasting serum cholesterol was increased in all cholesterol-supplemented mice compared with controls after 6 or 12 weeks of feeding (P<0.01). The total area of oil red O-stained atherosclerotic lesions was determined from digitally scanned photographs. In contrast to the control group, all mice in cholesterol-supplemented dietary groups 2 to 4 had lesions involving 7.01% to 12.79% area of the thoracic and abdominal aorta at 12 weeks (P<0.002, for each group versus control). The distribution pattern of atherosclerotic lesions was highly reproducible and comparable. The histological features of lesions in mice fed cholate-free or cholate-containing diets were similar. This study shows that sodium cholate is not necessary for the formation of atherosclerosis in LDLR(-/-) mice and that precisely defined semipurified diets are a valuable tool for the examination of diet-gene interactions.  (+info)

Alterations in detergent solubility of heterotrimeric G proteins after chronic activation of G(i/o)-coupled receptors: changes in detergent solubility are in correlation with onset of adenylyl cyclase superactivation. (7/61)

Prolonged G(i/o) protein-coupled receptor activation has been shown to lead to receptor internalization and receptor desensitization. In addition, it is well established that although acute activation of these receptors leads to inhibition of adenylyl cyclase (AC), long-term activation results in increased AC activity (especially evident on removal of the inhibitory agonist), a phenomenon defined as AC superactivation or sensitization. Herein, we show that chronic exposure to agonists of G(i)-coupled receptors also leads to a decrease in cholate detergent solubility of G protein subunits, and that antagonist treatment after such chronic agonist exposure leads to a time-dependent reversal of the cholate insolubility. With Chinese hamster ovary and COS cells transfected with several G(i/o)-coupled receptors (i.e., mu- and kappa-opioid, and m(4)-muscarinic), we observed that although no overall change occurred in total content of G(alphai)- and beta(1)-subunits, chronic agonist treatment led to a marked reduction in the ability of 1% cholate to solubilize G(betagamma) as well as G(alphai). This solubility shift is exclusively observed with G(alphai), and was not seen with G(alphas). The disappearance and reappearance of G(alphai) and G(betagamma) subunits from and to the detergent-soluble fractions occur with similar time courses as observed for the onset and disappearance of AC superactivation. Lastly, pertussis toxin, which blocks acute and chronic agonist-induced AC inhibition and superactivation, also blocks the shift in detergent solubility. These results suggest a correlation between the solubility shift of the heterotrimeric G(i) protein and the generation of AC superactivation.  (+info)

Compaction of DNA in an anionic micelle environment followed by assembly into phosphatidylcholine liposomes. (8/61)

A difficult problem concerning the interaction of DNA with amphiphiles of opposite charge above their critical micelle concentration is the propensity for aggregation of the condensed DNA complexes. In this study, this problem was addressed by attenuating amphiphile charge density within a cholate micelle environment. The amphiphile consisted of a cationic peptide, acetyl-CWKKKPKK-amide, conjugated to dilaurylphos-phatidylethanolamine. In the presence of cholate, multiple equivalents of cationic charge were required to bring about the completion of DNA condensation. At the end point of condensation, stable, soluble DNA-micelle complexes were formed, which by dynamic light scattering exhibited apparent hydro-dynamic diameters between 30 and 60 nm. Aggregation, as measured by static light scattering at 90 degrees and by turbidity, was not observed until further additions of peptide-lipid conjugate were made beyond the end point of DNA condensation. Liposome complexes containing the non-aggregated, compacted DNA were formed by adding dioleoylphosphatidylcholine followed by removing the cholate by dialysis. The resulting complexes were distributed within a narrow density range, the DNA was quantitatively assembled into the liposomes, and liposomes without DNA were not detected. Small particles were formed with a mean hydrodynamic diameter of 77 nm. The liposomal DNA showed complete retention of its supercoiled form and no detectable sensitivity to DNase (25 U/10 microg DNA, 1.5 h, 37 degrees C). The use of an anionic, dialyzable amphiphile to attenuate charge inter-actions between DNA and cationic amphiphiles is a useful technology for the quantitative assembly of compacted DNA into conventional liposomes, with complete protection against nuclease activity.  (+info)

I'm sorry for any confusion, but "Cholates" is not a recognized medical term or abbreviation in physiology, pathology, or pharmacology. It seems like there might be a spelling mistake or a misunderstanding. If you meant to ask about "cholesterol," I would be happy to help provide information on that.

Cholesterol is a type of lipid (fat) that is essential for the normal functioning of our bodies. It plays crucial roles in maintaining cell membrane structure, producing certain hormones, and serving as a precursor for vitamin D and bile acids. However, high levels of cholesterol in the blood can increase the risk of developing cardiovascular diseases.

If you have any questions or need more information about cholesterol or any other medical topic, please feel free to ask!

Cholate---CoA+ligase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC 6.2.1). ... Cholate-CoA ligase (EC 6.2.1.7, BAL, bile acid CoA ligase, bile acid coenzyme A ligase, choloyl-CoA synthetase, choloyl ... is an enzyme with systematic name cholate:CoA ligase (AMP-forming). This enzyme catalyses the following chemical reaction (1) ... ATP + cholate + CoA ⇌ {\displaystyle \rightleftharpoons } AMP + diphosphate + choloyl-CoA (2) ATP + (25R)-3alpha,7alpha,12alpha ...
"Americas Bean-to-Bar and Chocolatier Competition Winners 2019". International Cholate Awards. 26 June 2019. Cuozzo, Steve (19 ...
Salts of cholic acid are called cholates. Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids ...
Her doctoral research considered cholic acid and methyl cholate. Scott joined the faculty at the University of Cape Town in ... Scott, Janet Lesley (1995). Inclusion compounds of cholic acid and methyl cholate (Thesis). Place of publication not identified ...
Cholate statis is more common in obstructive cholestasis compared to non-obstructive cholestasis. During the cholate statis ... Cholestasis is often marked by cholate statis, which are a set of changes that occur in the periportal hepatocytes. ...
YufF (MrpF) appears to catalyze cholate efflux, possibly by a Na+ symport mechanism. It plays a major role in Na+ extrusion and ... multifunctional locus in Bacillus subtilis with roles in resistance to cholate and to Na+ and in pH homeostasis". Journal of ... and alkali but not cholate resistance". Journal of Bacteriology. 182 (20): 5663-70. doi:10.1128/jb.182.20.5663-5670.2000. PMC ...
The spermicides benzalkonium chloride and sodium cholate are used in some contraceptive sponges. Benzalkonium chloride might ...
"Enantioseparation of palonosetron hydrochloride by micellar electrokinetic chromatography with sodium cholate as chiral ...
"The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase". J Biol Chem. 275 (21): 15605-8 ...
"Stimulation of polyprenyl 4-hydroxybenzoate transferase activity by sodium cholate and 3-[(cholamidopropyl)dimethylammonio]-1- ...
"A Study of the Photochemical Response of o-Nitrobenzyl Cholate Derivatives in P(MMA-MAA) Matrices". Journal of Polymer Science ...
2000). "The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase". J. Biol. Chem. 275 (21 ...
"The effect of octylglucoside and sodium cholate in Staphylococcus epidermidis and Pseudomonas aeruginosa adhesion to soft ...
"The effect of octylglucoside and sodium cholate in Staphylococcus epidermidis and Pseudomonas aeruginosa adhesion to soft ...
The sheets in α-MoTe2 can be separated and dispersed in water with a sodium cholate surfactant and sonication. It forms an ...
... dehydroepiandrosterone and their glucuronide and sulfate conjugates in serum using sodium cholate micelle capillary ...
... cholate solution, 0.1 grams of cholate are dissolved in 10 mL of water. Volumetric flasks are the most appropriate piece of ...
This particular protein is responsible for the transport of taurocholate and other cholate conjugates from hepatocytes (liver ...
The best of these were the perfused hepatic mass (PHM) by quantitative laparoscopic liver spleen scan (QLSS) and oral Cholate ...
... cholates MeSH D04.808.105.225.130.330.850 - sodium cholate MeSH D04.808.105.225.261 - dehydrocholic acid MeSH D04.808.105.225. ... cholates MeSH D04.808.221.430.130.330.850 - sodium cholate MeSH D04.808.221.430.265 - dehydrocholic acid MeSH D04.808.221.430. ...
... (EC 1.17.99.5, cholate 7alpha-dehydroxylase, 7alpha-dehydroxylase, bile acid 7-dehydroxylase) ...
CDCA-NBD Cholate (CA) Cholecystokinin octapeptide (CCK-8) Dehydroepiandroserone-3-sulfate (DHEAS) Deltorphin II ...
... cholate-CoA ligase EC 6.2.1.8: oxalate-CoA ligase EC 6.2.1.9: malate-CoA ligase EC 6.2.1.10: carboxylic acid-CoA ligase (GDP- ... cholate-CoA ligase EC 6.2.1.30: phenylacetate-CoA ligase EC 6.2.1.31: 2-furoate-CoA ligase EC 6.2.1.32: anthranilate-CoA ligase ...
... a medication to treat acute poisoning Cholate-CoA ligase, or bile acid CoA ligase (BAL), an enzyme IBM Basic Assembly Language ...
Cholate-CoA ligase EC 6.2.1.8: Oxalate-CoA ligase EC 6.2.1.9: Malate-CoA ligase EC 6.2.1.10: Acid-CoA ligase (GDP-forming) EC ...
Chemical treatments- anionic detergent: (Sodium dodecyl sulfate (SDS)), sodium cholate, enzymatic agent (Trypsin), non-ionic ...
... cholate + CoA This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic ...
... which is a naturally occurring substance containing a mixture of bile salts and sodium cholate, a pure bile salt. Sodium ... liter Yeast extract 5.0 g Proteose Peptone 10.0 g Sodium thiosulfate 10.0 g Sodium citrate 10.0 g Ox gall 5.0 g Sodium cholate ...
... taurocholate and cholate), steroid conjugates, thyroid hormones, anionic oligopeptides, drugs, toxins and other xenobiotics. ...
Cholate---CoA+ligase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC 6.2.1). ... Cholate-CoA ligase (EC 6.2.1.7, BAL, bile acid CoA ligase, bile acid coenzyme A ligase, choloyl-CoA synthetase, choloyl ... is an enzyme with systematic name cholate:CoA ligase (AMP-forming). This enzyme catalyses the following chemical reaction (1) ... ATP + cholate + CoA ⇌ {\displaystyle \rightleftharpoons } AMP + diphosphate + choloyl-CoA (2) ATP + (25R)-3alpha,7alpha,12alpha ...
140.0 MM SODIUM CHOLATE 0.5ML   at Fishersci.com ... 140.0 mM Sodium cholate. Please note items from this supplier ...
europium cholate. hydrogel: a novel approach towards lanthanide sensitization. S. Bhowmik, S. Banerjee and U. Maitra, Chem. ... A self-assembled, luminescent europium cholate hydrogel: a novel approach towards lanthanide sensitization† ...
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Sem categoria cholate, cholate de pascoa, família, gabi cywinski, melhor chocolate, ovo de pascoa, pascoa, tiago e gabi, tiago ... cholate Teste do Chocolate. Posted on 04/04/2022. by Tiago Moraes ...
Our 74% Cacao Tanzanian Dark chocolate bar is simply made with Organic Tanzania Cacao, Turbinado Sugar (sugar in the raw) and cocoa butterSmall | 1.7ozRegular | 2.5oz *No Gluten, No Lecithin, Dairy Free, Nut Free
We established a high-trans fat, high-carbohydrate, and high-cholesterol, high-cholate diet-induced (HFHCCC) mouse model. C57BL ... Zhang, Q., Jin, Y., Xin, X. et al. A high-trans fat, high-carbohydrate, high-cholesterol, high-cholate diet-induced ... Bile salt is 0.5% sodium cholate. The composition of each diet is presented in Supplementary Tables 1 and 2. The animals were ... A possible reason is that sodium cholate can participate in the metabolism of bile acids and promote the metabolism and ...
Products Sodium cholate hydrate CAS:361-09-1, the detailed information and prices are supplied by the China manufacturer Wuhan ...
Cholate inhibits high-fat diet-induced hyperglycemia and obesity with acyl-CoA synthetase mRNA decrease. American Journal of ... Cholate inhibits high-fat diet-induced hyperglycemia and obesity with acyl-CoA synthetase mRNA decrease. In: American Journal ... Addition of 0.5% cholate to high-safflower oil diet completely prevented high fat- induced hyperglycemia and obesity in C57BL/ ... Cholate inhibits high-fat diet-induced hyperglycemia and obesity with acyl-CoA synthetase mRNA decrease. / Ikemoto, Shinji; ...
Sodium Cholate-Based Active Delipidation for Rapid and Efficient Clearing and Immunostaining of Deep Biological Samples. ... Sodium Cholate-Based Active Delipidation for Rapid and Efficient Clearing and Immunostaining of Deep Biological Samples. Small ... Here, SCARF, a sodium cholate (SC)-based active delipidation method, is developed for better clearing and immunolabeling of ...
Ni resin can be used for the purification of His-tagged fusion proteins under native or denaturing conditions The binding capacity of NEBExpress ® Ni Spin Columns is ≥ 1 mg per column
Meanwhile, the modified pectins exhibited superior adsorption for sodium cholate than ß-cyclodextrin or pectin itself, which ... Adsorption removal properties of ß-cyclodextrin-modified pectin on cholesterol and sodium cholate. ... with a maximum adsorption ability of 44.21 mg/g for cholesterol and 21.38 mg/g for sodium cholate. Furthermore, their ...
Cholate, taurocholate and chenodeoxycholate are not substrates. (Geyer et al., 2007). It is expressed in the CNS (Sreedharan et ...
Cholates. Krueger SK, Henderson MC, Siddens LK, VanDyke JE, Benninghoff AD, P Karplus A, Furnes B, Schlenk D, Williams DE. 2009 ...
Adsorption of cholate anions on layered double hydroxides: effects of temperature, ionic strength and pH journal, November 2008 ...
Conjugated bile acid biosynthesis, cholate =, taurocholate/glycocholate. Brite. Enzymatic reactions [BR:br08201]. 2. ...
Stack the cherry-flavored marshmallows with cholate on graham crackers. Heat the stacker in the microwave for 10 seconds or ...
Sodium cholate (purified) 5 g. 25 g D045. Detergent. deoxy-BIGCHAP 500 mg D316. Detergent. n-Dodecyl-β-D-maltoside 1 g. 5 g ...
Bile acid biosynthesis, cholesterol =, cholate/chenodeoxycholate. Orthology. K00037 3alpha-hydroxysteroid 3-dehydrogenase / ...
33] Still others have found human chorionic vein constriction when exposed to the bile acid cholate. This is postulated as a ...
As for hepatic fibrosis, the top three GO terms are GO:0047747 cholate-CoA ligase activity, GO:0008508 bile acid:sodium ... GO:0047747 affects the activity of cholate-CoA ligase, which catalyzes some reactions in liver. GO:0008508 is related with bile ...
Bicelle Composed of 1,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylcholine and Sodium Cholate. Author(s): Uchida, Noriyuki; Yanagi, ...
To investigate whether tubulin interacted with Gαq in SK-N-SH membranes, these membranes were extracted with sodium cholate and ... Immunoprecipitation. Membrane preparations were extracted with 1% sodium cholate in buffer A for 1 hr at 4°C with constant ...
This method makes it taste like a butterscotch brownie on the bottom, with a cholate chip texture on top . Very Yummy !! ...
I sometimes add it to cholate cake when I make it from scratch. ...
cholate + NADP(+) <=> 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH. Comment(s). ...
To evaluate the influence of the nanoformulation, the bulk catalyst without sodium cholate was used at the same concentration ... sodium cholate (w/w) aqueous solution using a vortex for 1 min and then a vibrating metallic tip at 30% amplitude for 1 min at ... The organic phase was poured into an aqueous solution containing sodium cholate (1.5%) as surfactant, the two phases were ... presumably because it was not possible to adjust the require amount of sodium cholate. ...
  • HR2-406-07/Detergent Screen #07 (A7), 0.5 ml - 140.0 mM Sodium cholate. (fishersci.com)
  • The effects of sodium cholate on high-fat diet-induced hyperglycemia and obesity were investigated. (elsevierpure.com)
  • Sodium Cholate-Based Active Delipidation for Rapid and Efficient Clearing and Immunostaining of Deep Biological Samples. (illumina.com)
  • Adsorption removal properties of ß-cyclodextrin-modified pectin on cholesterol and sodium cholate. (bvsalud.org)
  • Meanwhile, the modified pectins exhibited superior adsorption for sodium cholate than ß- cyclodextrin or pectin itself, which was attributed to hydrophobic interactions . (bvsalud.org)
  • P101 displayed the strongest adsorption performance, with a maximum adsorption ability of 44.21 mg/g for cholesterol and 21.38 mg/g for sodium cholate . (bvsalud.org)
  • Methods: Arc discharge SWNTs suspended in surfactants (1% W/V of sodium cholate and sodium dodecyl sulfate) was fabricated into buckypaper. (cdc.gov)
  • In contrast, the sodium-dependent as well as the sodium-independent uptake of cholate and the total uptake of taurocholate were non-competitively blocked, whereas EMD 56133 decreased the uptake of the cyclosomatostatin 008 in an uncompetitive manner. (nih.gov)
  • Also suitable are aqueous surfactant solutions, such as sodium cholate in water, and some polymer solutions. (tikalon.com)
  • Cholate, taurocholate and chenodeoxycholate are not substrates. (tcdb.org)
  • The transport of EMD 56133 was non-competitively inhibited by cholate (Ki = 126 microM) and taurocholate (Ki = 44 microM), and uncompetitively inhibited by the linear peptide EMD 51921. (nih.gov)
  • After breakfast, the serum conjugates of cholate and chenodeoxycholate increased significantly but thereafter the mean values remained high with less consistent responses to lunch and dinner, some subjects showing a peak and trough response to all three meals, while others showed a plateau response throughout the day. (bmj.com)
  • A similar pattern of results was seen after intravenous CCK, suggesting either preferential jejunal absorption of chenodeoxycholate conjugates and/or preferential hepatic clearance of cholate conjugates. (bmj.com)
  • We established a high-trans fat, high-carbohydrate, and high-cholesterol, high-cholate diet-induced (HFHCCC) mouse model. (biomedcentral.com)
  • Furthermore, the addition of cholate decreased blood insulin levels and prevented high-fat diet-induced decrease of glucose uptake in epitrochlearis. (elsevierpure.com)
  • In liver, cholate addition resulted in cholesterol accumulation and completely prevented high-fat diet-induced triglyceride accumulation. (elsevierpure.com)
  • This enzyme catalyses the following chemical reaction (1) ATP + cholate + CoA ⇌ {\displaystyle \rightleftharpoons } AMP + diphosphate + choloyl-CoA (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA ⇌ {\displaystyle \rightleftharpoons } AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA This enzyme requires Mg2+ for activity. (wikipedia.org)
  • Stevens collaborated with chemists to design new detergents, such as the cholate- based amphiphiles, that create smaller micelles, allowing the protein molecules to pack more closely and form better crystals. (the-scientist.com)
  • Mixed micelles containing 1-palmitoyl-2-oleoyl- sn-glycero -3-phosphocholine (POPC) and cholate were loaded with LRO antioxidants by means of two slightly different procedures, which surprisingly resulted in significant differences in both quality and quantity of incorporated carotenoids. (rsc.org)
  • Many studies have confirmed the role of high trans fatty acids, high sugars, and high cholesterol in NASH models, but few studies have involved the simultaneous use of high-trans fat, high-carbohydrate, high-cholesterol, high-cholate (HFHCCC) models to induce NASH. (biomedcentral.com)
  • To prepare Atol de arroz con cholate, you boil some water with cinnamon sticks, then add some rice and you wait for the rice to be soft and finally add Guatemalan real chocolate bars, a pinch of salt and maybe some sugar. (antiguadailyphoto.com)
  • These data indicate that the favorable effects of cholate could be partly the result of downregulation of ACS mRNA. (elsevierpure.com)
  • However, there was no change in the unsaturation index of fatty acids in skeletal muscles and in GLUT-4 levels by cholate. (elsevierpure.com)
  • GOs were stabilized in water (GOs), while prGO and rGOs were dispersed in sodium cholate. (nih.gov)
  • Additionally, sodium cholate stabilization significantly increased GO toxicity. (nih.gov)
  • The Fraction II solution is adjusted to a final concentration of 0.3% tri-n-butyl phosphate (TNBP) and 0.2% sodium cholate. (nih.gov)
  • After the addition of solvent (TNBP) and detergent (sodium cholate), the solution is heated to 30°C and maintained at that temperature for not less than 6 hours. (nih.gov)
  • Significant inactivation of enveloped viruses is achieved at the time of treatment of solubilized Cohn Fraction II with TNBP/sodium cholate. (nih.gov)
  • Methods: Arc discharge SWNTs suspended in surfactants (1% W/V of sodium cholate and sodium dodecyl sulfate) was fabricated into buckypaper. (cdc.gov)
  • A macrocyclic and a linear trimer of a facially amphiphilic cholate building block were labeled with a fluorescent dansyl group. (bepress.com)
  • Deoxycholate is more membrane damaging than cholate and its conjugates. (nih.gov)
  • Le prix des produits peut varier en fonction de la date et de la zone sélectionnées. (flowers4honduras.com)