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ChlorpropamideFlushingDemeclocyclineSuppositoriesChlorothiazideDiabetes InsipidusErythemaTolbutamideBlood GlucoseSulfonylurea CompoundsElectronic MailDiabetes Mellitus, Type 1Food Dispensers, AutomaticDiabetes MellitusDiabetes Mellitus, Type 2Postal ServiceInternetInsulinHypoglycemic AgentsGlucoseHypoglycemiaUltraviolet RaysDNA RepairCentrifugation, IsopycnicCricetinaeDNA DamageCHO CellsUnconsciousnessTabletsCandyPatient Acceptance of Health CareAgropyronNesidioblastosisPathology, ClinicalPancreatic DiseasesHyperinsulinismPancreatectomyPoison Control CentersPoisoningInformation CentersGas PoisoningNational Health Planning Information Center (U.S.)Poisons
Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)Flushing: A transient reddening of the face that may be due to fever, certain drugs, exertion, stress, or a disease process.Demeclocycline: A TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.Suppositories: Medicated dosage forms that are designed to be inserted into the rectal, vaginal, or urethral orifice of the body for absorption. Generally, the active ingredients are packaged in dosage forms containing fatty bases such as cocoa butter, hydrogenated oil, or glycerogelatin that are solid at room temperature but melt or dissolve at body temperature.Chlorothiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)Diabetes Insipidus: A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of causes.Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)Blood Glucose: Glucose in blood.Sulfonylurea CompoundsElectronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.Food Dispensers, Automatic: Mechanical food dispensing machines.Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.Postal Service: The functions and activities carried out by the U.S. Postal Service, foreign postal services, and private postal services such as Federal Express.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).Hypoglycemic Agents: Substances which lower blood glucose levels.Glucose: A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.Ultraviolet Rays: That portion of the electromagnetic spectrum immediately below the visible range and extending into the x-ray frequencies. The longer wavelengths (near-UV or biotic or vital rays) are necessary for the endogenous synthesis of vitamin D and are also called antirachitic rays; the shorter, ionizing wavelengths (far-UV or abiotic or extravital rays) are viricidal, bactericidal, mutagenic, and carcinogenic and are used as disinfectants.DNA Repair: The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.Centrifugation, Isopycnic: A technique used to separate particles according to their densities in a continuous density gradient. The sample is usually mixed with a solution of known gradient materials and subjected to centrifugation. Each particle sediments to the position at which the gradient density is equal to its own. The range of the density gradient is usually greater than that of the sample particles. It is used in purifying biological materials such as proteins, nucleic acids, organelles, and cell types.Cricetinae: A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.DNA Damage: Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.CHO Cells: CELL LINE derived from the ovary of the Chinese hamster, Cricetulus griseus (CRICETULUS). The species is a favorite for cytogenetic studies because of its small chromosome number. The cell line has provided model systems for the study of genetic alterations in cultured mammalian cells.Unconsciousness: Loss of the ability to maintain awareness of self and environment combined with markedly reduced responsiveness to environmental stimuli. (From Adams et al., Principles of Neurology, 6th ed, pp344-5)Tablets: Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)Candy: Sweet food products combining cane or beet sugars with other carbohydrates and chocolate, milk, eggs, and various flavorings. In the United States, candy refers to both sugar- and cocoa-based confections and is differentiated from sweetened baked goods; elsewhere the terms sugar confectionary, chocolate confectionary, and flour confectionary (meaning goods such as cakes and pastries) are used.Patient Acceptance of Health Care: The seeking and acceptance by patients of health service.Agropyron: A plant genus of the family POACEAE. The common name of wheatgrass is also used for other plants in the family.Nesidioblastosis: An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the PANCREAS and CONGENITAL HYPERINSULINISM. It is due to focal hyperplasia of pancreatic ISLET CELLS budding off from the ductal structures and forming new islets of Langerhans. Mutations in the islet cells involve the potassium channel gene KCNJ11 or the ATP-binding cassette transporter gene ABCC8, both on CHROMOSOME 11.Pathology, Clinical: A subspecialty of pathology applied to the solution of clinical problems, especially the use of laboratory methods in clinical diagnosis. (Dorland, 28th ed.)Pancreatic Diseases: Pathological processes of the PANCREAS.Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.Pancreatectomy: Surgical removal of the pancreas. (Dorland, 28th ed)Poison Control Centers: Facilities which provide information concerning poisons and treatment of poisoning in emergencies.Poisoning: A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.Information Centers: Facilities for collecting and organizing information. They may be specialized by subject field, type of source material, persons served, location, or type of services.Gas PoisoningNational Health Planning Information Center (U.S.): A center in the HEALTH RESOURCES ADMINISTRATION Division of Planning Methods and Technology which provides access to current information on health planning and resources development.Poisons: Substances which, when ingested, inhaled, or absorbed, or when applied to, injected into, or developed within the body in relatively small amounts may, by their chemical action, cause damage to structure or disturbance of function. (From Dorland, 27th ed)

X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli. (1/73)

Type 1 pili-adhesive fibers expressed in most members of the Enterobacteriaceae family-mediate binding to mannose receptors on host cells through the FimH adhesin. Pilus biogenesis proceeds by way of the chaperone/usher pathway. The x-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli at 2.5 angstrom resolution reveals the basis for carbohydrate recognition and for pilus assembly. The carboxyl-terminal pilin domain of FimH has an immunoglobulin-like fold, except that the seventh strand is missing, leaving part of the hydrophobic core exposed. A donor strand complementation mechanism in which the chaperone donates a strand to complete the pilin domain explains the basis for both chaperone function and pilus biogenesis.  (+info)

A systematic review of drug induced ocular reactions in diabetes. (2/73)

AIMS: To conduct a systematic review of drug induced adverse ocular effects in diabetes to determine if this approach identified any previously unrecognised adverse drug effects; to make a preliminary assessment of the feasibility of this approach in identifying adverse drug reactions; and to assess the current accessibility of this information to prescribing physicians. METHODS: Literature search of online biomedical databases. The search strategy linked eye disorders with adverse drug reactions and diabetes. Source journals were classified as medical, pharmaceutical, diabetes related, or ophthalmological. It was determined whether the reactions identified were recorded in drug datasheets and the British National Formulary. RESULTS: 63 references fulfilled the selection criteria, of which 45 were considered to be relevant to the study. The majority of these were case reports but cross sectional surveys, case-control and cohort studies, and review articles were also identified. 61% of the reactions were not recorded in the British National Formulary and 41% were not recorded in the datasheets. 55% appeared in specialist ophthalmology journals. CONCLUSIONS: This is a feasible approach to the identification of adverse drug reactions. Adverse reactions not listed in the most commonly used reference sources were found. The majority were published in specialist ophthalmology journals which might not be seen by prescribing physicians.  (+info)

Chlorpropamide upregulates antidiuretic hormone receptors and unmasks constitutive receptor signaling. (3/73)

The mechanism by which chlorpropamide (CP) treatment promotes antidiuresis is unknown. CP competitively inhibited antidiuretic hormone (ADH) binding and adenylyl cyclase (AC) stimulation (inhibition constants K(i) and K'(i) of 2.8 mM and 250 microM, respectively) in the LLC-PK(1) cell line. CP (333 microM) increased the apparent K(a) of ADH for AC activation (0.31 vs. 0.08 nM) without affecting a maximal response, suggesting competitive antagonism. Because CP lowers "basal" AC activity and the AC activation-ADH receptor occupancy relationship (A-O plots), it is an ADH inverse agonist. Twenty-four-hour CP exposure (100 microM) upregulated the ADH receptors without affecting affinity. This lowered K(a) and increased basal AC activity and maximal response (1. 86 vs. 1.35 and 14.9 vs. 10.6 fmol cAMP. min(-1). 10(3) cells(-1), n = 6, P<0.05). NaCl, which potentiates ADH stimulation, also increased basal AC activity. This, together with the CP-ADH inverse agonism and increased basal AC activity at higher receptor density, unmasks constitutive receptor signaling. The CP-ADH inverse agonism explains receptor upregulation and predicts the need for residual ADH with functional isoreceptors for CP-mediated antidiuresis. This could be why CP ameliorates partial central diabetes insipidus but not nephrogenic diabetes insipidus.  (+info)

Inhibition of CFU-E/BFU-E by 3'-azido-3'-deoxythymidine, chlorpropamide, and protoporphirin IX zinc (II): a comparison between direct exposure of progenitor cells and long-term exposure of bone marrow cultures. (4/73)

Erythropoiesis occurs in two stages: proliferation amplifies cell number, and differentiation stimulates the acquisition of the functional properties of red blood cells. The erythroid colony-forming unit (CFU-E) amplifies the differentiation process in response to erythropoietic stress in vitro, whereas the burst-forming unit (BFU-E), which is not particularly sensitive to erythropoietin stimulation, gives rise to the CFU-E and, when stimulated, produces morphologically-identifiable erythroid colonies. The aim of this work was to evaluate the toxic effects of the antiviral agent, 3'-azido-3'-deoxythymidine (AZT), the antidiabetic drug, chlorpropamide (CLP), and the heme-analogous compound, protophorphirin IX zinc (II) (ZnPP), on the proliferation of erythroblastic progenitors by using human umbilical-cord blood cells and murine progenitors from long-term bone marrow cultures. All these agents may interfere with the hemopoietic process, causing myelotoxicity as an adverse effect via different mechanisms. Our results showed selective toxicity of the three drugs on the erythroid progenitors (IC(50): AZT 0.35 +/- 0.13 microM, ZnPP 23.34 +/- 1.16 microM, CLP 1.07 +/- 0.27 mM), with respect to the myeloid progenitors (IC(50): AZT 0.8 microM, ZnPP 103.9 +/- 3.9 microM and CLP > 2800 microM). The IC(50) values were well correlated with peak plasma levels reached in vivo by the drugs. There was a marked similarity between the drug sensitivities of the human and murine progenitors but differences in toxicity exerted by the drugs on the basis of the time of exposure. Drug treatment of long-term cultures, followed by the clonogenic assay of progenitors collected from them in the absence of the drugs, generally resulted in a lower hematotoxicity.  (+info)

Investigation of hypoglycemic properties of rectal suppositories with chlorpropamide. (5/73)

Rectal suppositories with chlorpropamide and suppositories with chlorpropamide in the dispersion system with urea were prepared. Witepsol H15 and H19 and a polyoxyethyleneglycol mixture were used as bases. Rabbits were tested for blood-glucose level. The animals have been administered with prepared suppositories and commercial tablets. It was found that the suppositories prepared on the basis Witepsol H 15 with the dispersed chlorpropamide caused a much higher decrease of blood-glucose level than commercial tablets.  (+info)

Crystal doping aided by rapid expansion of supercritical solutions. (6/73)

The purpose of this study was to test the utility of rapid expansion of supercritical solution (RESS) based cocrystallizations in inducing polymorph conversion and crystal disruption of chlorpropamide (CPD). CPD crystals were recrystallized by the RESS process utilizing supercritical carbon dioxide as the solvent. The supercritical region investigated for solute extraction ranged from 45 to 100 degrees C and 2000 to 8000 psi. While pure solute recrystallization formed stage I of these studies, stage II involved recrystallization of CPD in the presence of urea (model impurity). The composition, morphology, and crystallinity of the particles thus produced were characterized utilizing techniques such as microscopy, thermal analysis, x-ray powder diffractometry, and high-performance liquid chromatography. Also, comparative evaluation between RESS and evaporative crystallization from liquid solvents was performed. RESS recrystallizations of commercially available CPD (form A) resulted in polymorph conversion to metastable forms C and V, depending on the temperature and pressure of the recrystallizing solvent. Cocrystallization studies revealed the formation of eutectic mixtures and solid solutions of CPD + urea. Formation of the solid solutions resulted in the crystal disruption of CPD and subsequent amorphous conversion at urea levels higher than 40% wt/wt. Consistent with these results were the reductions in melting point (up to 9 degrees C) and in the DeltaH(f) values of CPD (up to 50%). Scanning electron microscopy revealed a particle size reduction of up to an order of magnitude upon RESS processing. Unlike RESS, recrystallizations from liquid organic solvents lacked the ability to affect polymorphic conversions. Also, the incorporation of urea into the lattice of CPD was found to be inadequate. In providing the ability to control both the particle and crystal morphologies of active pharmaceutical ingredients, RESS proved potentially advantageous to crystal engineering. Rapid crystallization kinetics were found vital in making RESS-based doping superior to conventional solvent-based cocrystallizations.  (+info)

Effect of sulfonylureas on triglyceride metabolism in the rat liver: possible role of the lysosomes in hepatic lipolysis. (7/73)

It has been suggested previously that chlorpropamide and other hypoglycemic sulfonylureas interfere with hepatic triglyceride breakdown. Since ketogenesis from endogenous hepatic lipid stores is a measure of hepatic triglyceride hydrolysis, ketogenesis derived from endogenous lipids as well as ketogenesis derived from exogenously added isotopic oleate was determined in isolated hepatocytes from fasted rats in an attempt to identify the nature of the direct effects of sulfonylureas on hepatic lipid metabolism. Ketogenesis from endogenous lipids was inhibited by 1 mM chlorpropamide, while ketone production from exogenous oleate did not change. The effect of chlorpropamide on hepatic triglyceride metabolism was further studied in the isolated perfused liver of normal rats in the presence of a continuous [3H]oleate infusion and in isolated liver cells incubated in the presence of [3H]oleate. In liver perfusion experiments, 1 mM chlorpropamide enhanced the incorporation of tritium into triglycerides (but not other lipid classes) and increased both liver triglyceride content and triglyceride secretion. Using isolated cells similar effects could be demonstrated at 0.5 mM chlorpropamide. Chlorpropamide, tolbutamide, and carbutamide, all of which inhibited endogenous ketogenesis in isolated liver cells, also inhibited lysosomal triglyceride lipase activity in rat liver homogenates. The drugs were not inhibitory towards alkaline lipase activity. Demethylglycodiazin (2-benzolsulfonamid--5-(beta-hydroxyethoxy)-pyrimidin), which did not inhibit endogenous ketogenesis in isolated liver cells, did not affect lysosomal lipase activity. The lysosomotropic drug chloroquine was markedly antiketogenic when tested in liver cells. The reduction in endogenous ketogenesis, the enhanced accumulation of liver triglycerides, and the stimulation of hepatic triglyceride output by chlorpropamide are ascribed to an interference of the drug with hepatic triglyceride breakdown. The present results also suggest that the lysosomes play a significant role in hepatic lipolysis.  (+info)

A drug-specific leuco-agglutinin in a fatal case of agranulocytosis due to chlorpromazine. (8/73)

A fatal case of agranulocytosis due to chlorpromazine is reported. Mechanisms other than immunological are generally believed to be responsible for chlorpromazine-induced agranulocytosis. However, the demonstration of a drug-specific leuco-agglutinin in the serum of this patient suggests that an immunological mechanism was responsible for the agranulocytosis.  (+info)

Chromatographic studies of chlorpropamide interactions with normal and glycated human serum albumin based on affinity...Chromatographic studies of chlorpropamide interactions with normal and glycated human serum albumin based on affinity...
TY - JOUR. T1 - Chromatographic studies of chlorpropamide interactions with normal and glycated human serum albumin based on affinity microcolumns. AU - Tao, Pingyang. AU - Li, Zhao. AU - Matsuda, Ryan. AU - Hage, David S.. PY - 2018/10/15. Y1 - 2018/10/15. N2 - Sulfonylurea drugs have significant binding to proteins in blood, with most of this binding believed to occur with human serum albumin (HSA). High performance affinity chromatography and affinity microcolumns containing immobilized HSA were used to investigate binding by the sulfonylurea drug chlorpropamide to normal HSA and glycated HSA, which is a modified form of HSA that has an increased serum concentration in diabetes. Experiments employing frontal analysis indicated that the binding by chlorpropamide gave a good fit to a two-site model for both normal HSA and glycated HSA samples that were representative of controlled or advanced diabetes. These interactions involved a set of moderate-to-high affinity sites and a set of lower ...
Chlorpropamide - DrugBankChlorpropamide - DrugBank
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. Chlorpropamide is not recommended for the
Ferring pharmaceuticals inc evokes constant talking of many viewers, in fact basically as a result of chlorpropamideFerring pharmaceuticals inc evokes constant talking of many viewers, in fact basically as a result of chlorpropamide
pfizer inc. plans to move its production facilities to China in two calendar years, which will actually allow testing for more effective chlorpropamide packaging lines allocation. You gonna need to look out songs for antihistamines that contain decongestants like stanozolol or chlorpropamide. Heres a retarded case report of somebody taking 6g of controlled drug who developed and increased interest in basic sexual intercourse and vestibula
Chlorpropamide inhibition of excision repair and postreplication repair of ultraviolet damage in Chinese hamster ovary cellsChlorpropamide inhibition of excision repair and postreplication repair of ultraviolet damage in Chinese hamster ovary cells
Chlorpropamide, an oral hypoglycemic agent, was tested for effects on excision repair and postreplication repair of ultraviolet (UV) damage of DNA in CHO-K1 cells. The technique used to measure excision repair involved isopycnic centrifugation of density- and isotopically-labeled DNA. Alkaline sucro …
Chlorpropamide (discontinued in the UK)Chlorpropamide (discontinued in the UK)
Chlorpropamide is a type of medicine called a sulphonylurea. It is used to help control blood sugar levels in people with type 2 diabetes.
ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes<...ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes<...
TY - JOUR. T1 - ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes. AU - Suzuki, Yoshihiko. AU - Taniyama, Matsuo. AU - Muramatsu, Tara. AU - Higuchi, Susumu. AU - Ohta, Shigeo. AU - Atsumi, Yoshihito. AU - Matsuoka, Kempei. PY - 2004/8/1. Y1 - 2004/8/1. N2 - In the history of diabetes, chlorpropamide alcohol flushing test (CPAF) was a big topic in the 1970s to 1980s. Alcohol tolerance after chlorpropamide has prognostic significance, with the intolerant group (CPAF-positive group) being less prone to develop vascular complication than the tolerant group (CPAF-negative group). A mechanism of CPAF has been regarded as the inhibition of aldehyde dehydrogenase 2 (ALDH2) by an N1-alkyl-substituted derivative of chlorpropamide, and the expression of these mutations of ALDH2 and alcohol dehydrogenase 2 (ADH2) could determine the alcohol tolerance among the Japanese population. Therefore, we hypothesized that expression of different ALDH2 and ADH2 polymorphisms may ...
Pharmacophore An International Research Journal: AbstractPharmacophore An International Research Journal: Abstract
A study of 40 chlorpropamide derivatives, QSAR (Quantitative Structure Activity Relationship) and molecular docking approaches were applied to explore the structural requisites of chlorpropamide derivatives for CYTOCHROME P450 2C9 inhibitory activity. A set of forty chlorpropamide, was modeled, within the hypermolecule strategy; the predicted activity was LD50 and prediction was done on similarity clusters with the leaders chosen as the best docked ligands on the CYTOCHROME P450 2C9.. [PDF] , ...
Chlorpropamide-alcohol flushing, malar thermal circulation ind...Chlorpropamide-alcohol flushing, malar thermal circulation ind...
Chlorpropamide-alcohol flushing, malar thermal circulation index, and baseline malar temperature.: Chlorpropamide-alcohol flushing (CPAF) has been advanced and
United Kingdom prospective diabetes study (UKPDS) 13: relative efficacy of randomly allocated diet, sulphonylurea, insulin, or...United Kingdom prospective diabetes study (UKPDS) 13: relative efficacy of randomly allocated diet, sulphonylurea, insulin, or...
The drugs that were studied had similar effects on fasting plasma glucose concentrations. Chlorpropamide was slightly more effective than glibenclamide, partly because it induced fewer hypoglycaemic reactions. The incidence of hypoglycaemic reactions depended on the drug used and the severity of the diabetes. Most reactions were minor with less than 2% of patients having serious hypoglycaemic reactions that required third party intervention each year. Patients taking glibenclamide reported a higher incidence of minor hypoglycaemic attacks than those taking chlorpropamide but similar rates for major episodes.. Ultralente insulin was accepted by 73% of asymptomatic patients compared with about 90% of those offered tablets. This suggests that a once daily insulin injection usually caused little inconvenience, and no specific instructions were given about the timing or amount of meals or exercise. The moderate weight gain in patients treated by insulin was similar to that in those treated with ...
Chlorpropamide | Daviss Drug Guide for Rehabilitation Professionals | F.A. Davis PT Collection | McGraw-Hill MedicalChlorpropamide | Davis's Drug Guide for Rehabilitation Professionals | F.A. Davis PT Collection | McGraw-Hill Medical
Monitor signs of fluid-electrolyte imbalance due to syndrome of inappropriate antidiuretic hormone (SIADH). SIADH causes increased water retention that leads to relatively low sodium concentration (hyponatremia). Symptoms include confusion, lethargy, weakness, myoclonus, and depressed reflexes. Severe or sudden onset may also cause seizures, ataxia, nystagmus, tremor, dysarthria, dysphagia, and coma. Notify physician if these signs occur. ...
Stillwater Medical | Chlorpropamide tabletsStillwater Medical | Chlorpropamide tablets
Visit your doctor or health care professional for regular checks on your progress.. A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.. Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.. Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.. Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.. Do not skip meals. Ask your doctor or health care professional ...
Chlorpropamide tabletsChlorpropamide tablets
Visit your doctor or health care professional for regular checks on your progress.. A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.. Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.. Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.. Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.. Do not skip meals. Ask your doctor or health care professional ...
Chlorpropamide tabletsChlorpropamide tablets
Visit your doctor or health care professional for regular checks on your progress.. A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.. Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.. Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.. Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.. Do not skip meals. Ask your doctor or health care professional ...
CHNOLA | Chlorpropamide tabletsCHNOLA | Chlorpropamide tablets
Visit your doctor or health care professional for regular checks on your progress.. A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.. Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.. Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.. Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.. Do not skip meals. Ask your doctor or health care professional ...
Chlorpropamide tablets | UCLA Health Library, Los Angeles, CAChlorpropamide tablets | UCLA Health Library, Los Angeles, CA
Visit your doctor or health care professional for regular checks on your progress.. A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.. Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.. Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.. Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.. Do not skip meals. Ask your doctor or health care professional ...
Chlorpropamide tabletsChlorpropamide tablets
Visit your doctor or health care professional for regular checks on your progress.. A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.. Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.. Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.. Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.. Do not skip meals. Ask your doctor or health care professional ...
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RESOURCES: Hormone Health Network: "Nondiabetic Hypoglycemia." Mayo Facility: "Hypoglycemia." Allina Health And Wellness: "Non-diabetic Hypoglycemia." Endotext: "Non-Diabetic Hypoglycemia." UW Health: "Nutrition Monitoring of Low Blood Glucose without Diabetic Issues (Postprandial Syndrome as well as Responsive Hypoglycemia)." Memorial Sloan Kettering Cancer Center: "How to Give an Emergency Situation Glucagon Shot to Treat Reduced Blood Glucose." American Diabetes Association: "Hypoglycemia (Low Blood Sugar)." Joslin Diabetes Facility: "Driving with Diabetes," "How To Treat A Low Blood Glucose," "Is Low Blood Sugar (Hypoglycemia) Dangerous?" "Oral Diabetes Medications Summary Graph," "Prandin Oral Hypoglycemic Agent." Journal of the American Medical Organization: "Factitious Hypoglycemia Because Of Chlorpropamide: Record of an Instance, with Professional Similarity to an Islet Cell Growth of the Pancreatic." AMN Healthcare: "Breakthroughs in Diabetes, Component II: Oral Medicines." ...
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It is well known that there is a progressive deterioration in beta-cell function over time in type 2 diabetes (DM2), as indicated by the UKPDS (United Kingdom Prospective Diabetes Study), regardless of therapy allocation, albeit conventional (mainly diet), insulin, chlorpropamide, glibenclamide or metformin treatment. Moreover, the pancreatic islet function was found to be about 50% of normal at the time of diagnosis, independent of the degree of insulin resistance, with the reduction in function probably commencing 10-12 years prior to diagnosis and aggravated by increasing fasting plasma glucose levels.. Optimal metabolic control, especially early intensive glycemic control, plays a role in the prevention of progressive beta cell dysfunction and possibly destruction of the betacells with worsening of diabetes. Many reports have shown that induction of normoglycemia in DM2 results in both improved beta cell function and insulin resistance.The major therapeutic drawback using native GLP-1 is its ...
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if you have been using insulin or taking chlorpropamide (Diabinese).. Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs. Talk to your doctor about the risks and benefits of treating your diabetes with glyburide.. FDA pregnancy category C. It is not known whether glyburide will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether glyburide passes into breast milk or if it could harm a nursing baby.. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have low blood sugar while taking glyburide.. Important safety information:. You should not use this medication if you are allergic to glyburide, ...
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if you have been using insulin or taking chlorpropamide (Diabinese).. Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs. Talk to your doctor about the risks and benefits of treating your diabetes with glyburide.. FDA pregnancy category C. It is not known whether glyburide will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether glyburide passes into breast milk or if it could harm a nursing baby.. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have low blood sugar while taking glyburide.. Important safety information:. You should not use this medication if you are allergic to glyburide, ...
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if you have been using insulin or taking chlorpropamide (Diabinese).. Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs. Talk to your doctor about the risks and benefits of treating your diabetes with glyburide.. FDA pregnancy category C. It is not known whether glyburide will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether glyburide passes into breast milk or if it could harm a nursing baby.. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have low blood sugar while taking glyburide.. Important safety information:. You should not use this medication if you are allergic to glyburide, ...
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if you have been using insulin or taking chlorpropamide (Diabinese).. Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs. Talk to your doctor about the risks and benefits of treating your diabetes with glyburide.. FDA pregnancy category C. It is not known whether glyburide will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether glyburide passes into breast milk or if it could harm a nursing baby.. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have low blood sugar while taking glyburide.. Important safety information:. You should not use this medication if you are allergic to glyburide, ...
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Mark Sherry - Outburst Radioshow 383 on AH.FM 19-09-2014Mark Sherry - Outburst Radioshow 383 on AH.FM 19-09-2014
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Allan Dean Sherry - Endowed Professorships and Chairs - The University of Texas at DallasAllan Dean Sherry - Endowed Professorships and Chairs - The University of Texas at Dallas
Dean Sherrys career at UT Dallas began nearly 40 years ago and has since grown as much as the campus itself. Sherry researches ways of refining diagnostic tools that may one day lead to better, more insightful diagnoses of medical conditions ranging from cancer to heart disease.. Sherry also is the director of the Advanced Imaging Research Center housed at UT Southwestern Medical Center, where he has a dual appointment as a professor of radiology.. He and his colleagues are developing tracer molecules that can be used with magnetic resonance imaging to measure changes in metabolic pathways present in certain diseases. They are also developing molecules that report on some key biological indicators of tumors using MRI. "We anticipate new applications for imaging," Sherry said, "and with the research capabilities available here and at UT Southwestern, it will be much easier to translate research into clinical use. We are interested in visualizing metabolism in the human body in real time as it ...
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Patients with Type I, i.e., insulin-deficient diabetes, Type II or non-insulin-deficient diabetes, and impaired glucose tolerance or so-called chemical diabetes are variably predisposed to develop macroangiopathy, i.e., atherosclerosis, microangiopathy or basement membrane thickening, and neuropathy. Once these morphologic changes appear, they in all probability will remain irreversible even when precise regulation is attained. Hence prevention is the only realistic goal.. ...
Cohort analysis of HbA1cCohort analysis of HbA1c
The Lancet has published the results of an observational retrospective cohort study that aimed to assess the relationship between HbA1c and all-cause mortality. The study is accompanied by a comment article that discusses the findings further.. The study collected data from the UK General Practice Research Database for 27,965 individuals aged 50 years and older with a diagnosis of type 2 diabetes. The data were analysed for HbA1c and all-cause mortality. A secondary analysis looked at "large-vessel disease" which was defined as any record of myocardial infarction, stroke, coronary revascularisation, carotid or peripheral arterial revascularisation or angina.. The analysis found an association between low and high mean HbA1c and increased risk of all-cause mortality and cardiac events. The lowest risks were associated with an HbA1c of 7.5% which provides some support to the current treatment targets recommended by the National Institute for Health and Clinical Excellence (NICE) for patients on ...
Farewell to SherryFarewell to Sherry
... It is with great sadness that one of our dearest EPR has past away on the 10th December 2013. Sherry was one of the original EPR Co...
Farewell to SherryFarewell to Sherry
... It is with great sadness that one of our dearest EPR has past away on the 10th December 2013. Sherry was one of the original EPR Co...
Sherry KidneysSherry Kidneys
Most tapas bars in Spain serve Sherry kidneys, though at home it can be served with rice or pasta as a main meal. You can add sliced mushrooms to increase the number of portions.
Sherry Snider | CaringBridgeSherry Snider | CaringBridge
Visit Sherry Sniders CaringBridge website where youll find the latest updates and a place to share messages of love, hope & compassion.
Sherry Kincaid (kincaid91trk) on PinterestSherry Kincaid (kincaid91trk) on Pinterest
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Hi Wray, A couple of questions. I am currently taking 100mgs of Prometrium. I have tried cream before and my blood tests revealed that I was not
IP] Re: insulin-pumpers-digest V4 #868IP] Re: insulin-pumpers-digest V4 #868
Sherry take it from a 40 year diabetic two things you will never see: 1. A diabetic that will never cheated on his/her diet 2. A diabetic that never behaved himself and kept extremely good and complete records for two weeks prior to a visit to the endo. Having said all that, I just got a Hba1c of 6.2 for my last visit. BW ---------------------------------------------------------- for HELP or to subscribe/unsubscribe, contact: [email protected] send a DONATION http://www.Insulin-Pumpers.org/donate.shtml ...
WDBJ 7 news at 5 for 04/18/97WDBJ 7 news at 5 for 04/18/97
SHERRY WAGSTAFF/LA LECHE LEAGUE: ITS EASIEST FOR THE MOTHER, I DONT HAVE ANYTHING TO DO BUT PICK UP MY BABY AND PUT HIM TO THE BREAST, IN THE MIDDLE OF THE NIGHT, WE DONT TURN ON A LIGHT, I JUST GO AS SOON AS I HEAR HIM SNARKLE I PICK HIM UP AND PUT HIM TO THE BREAST AND FIVE MINUTES HES BACK DOWN. TO ME THATS VERY EASY. )) ...
Ron Zacapa Centenario 23 Rum ReviewRon Zacapa Centenario 23 Rum Review
Ron Zacapa Centenario 23 is a solera blended rum aged between 6 and 23 years in American oak and Sherry barrels. It has quite a high sugar and additive content.
Downie, S. A.<...Downie, S. A.<...
Fingerprint Dive into the research topics where Sherry A. Downie is active. These topic labels come from the works of this person. Together they form a unique fingerprint. ...
ChlorpropamideChlorpropamide
All material found on the BC Drug and Poison Information Centre (DPIC) website is provided for informational purposes only. It is not meant to replace the expert advice of a healthcare professional such as a physician, pharmacist, nurse or qualified poison specialist. Use of this site is governed and restricted by specific terms of use. Please review the full terms and conditions below prior to using the DPIC website. In the event of a poisoning emergency, call your local poison control centre immediately. Portions of this web site are intended for healthcare professionals. Interpretation and application of information may require more detailed explanation than contained herein, particularly regarding any clinical information that is found in or linked to this site. Patients are advised to consult their health care provider regarding diagnosis and treatment, and for assistance in interpreting these materials and applying them in individual cases. ...
Hyperinsulinaemic hypoglycaemia due to chlorpropamide-induced nesidioblastosis. | Journal of Clinical PathologyHyperinsulinaemic hypoglycaemia due to chlorpropamide-induced nesidioblastosis. | Journal of Clinical Pathology
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First Generation SulfonylureaFirst Generation Sulfonylurea
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Kinetics-effect relations of insulin-releasing drugs in patients with type 2 diabetes - Lund UniversityKinetics-effect relations of insulin-releasing drugs in patients with type 2 diabetes - Lund University
Sulfonylureas and glinides have similar mechanisms of action but differ in receptor affinity and binding sites and in absorption and elimination rates. This promotes differences in potency, rate of onset, and duration of action. While prominent in single-dose studies, these differences have less importance during long-term sulfonylurea treatment: at ordinary dosages, rapid- and short-acting (glipizide) and slow- and long-acting (glyburide) sulfonylureas maintained continuously effective plasma levels and similar 24-h glucose control. Moreover, there was no difference in patient outcome between the first-generation sulfonylurea chlorpropamide and the second-generation glyburide in the U.K. Prospective Diabetes Study. However, the risk of long-lasting and hence dangerous hypoglycemia is higher with these two long-acting sulfonylureas. Conversely, this risk should be low with the short-acting glinides, but seemingly at the expense of less effective glucose control. The most important ...
Diabetes - Prevention And Cure part 3 - Yum Yum Healthy EatingDiabetes - Prevention And Cure part 3 - Yum Yum Healthy Eating
The Treatment And Cure. For type 1 diabetes:. Daily injections of insulin are necessary. One to four daily injections are required to control blood glucose levels. Long acting and rapid acting insulin preparations are available; a combination of the two kinds is often prescribed. A strict diet and schedule of meals are necessary to control blood glucose levels. Your doctor may recommend a diet low in fat, salt, and cholestrol, and May advice you to see a nutritionist for dietary planning. Because both exercise and insulin lower glucose levels. Exercise and insulin injections must be timed so that they do not combine to cause a dangerous drop in blood sugar (hypoglycemia). Strict adherence to the timetable of injections, meals, and exercise is necessary for proper management of the disease.. For type 2 diabetes:. A low diet in fat and other calories, in addition to regular exercise, is necessary to control weight. Oral hypoglycemic drugs, such as tolbutamide, chlorpropamide, tolazamide, ...
Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years | The BMJRelation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years | The BMJ
These results confirm that reduced fetal growth is associated with increased risk of non-insulin dependent diabetes and suggest a specific association with thinness at birth. Although the relation between size at birth and risk of diabetes is clearly non-linear, there is no evidence of the U shaped relation between diabetes and birth weight reported in Pima Americans, in whom non-insulin dependent diabetes is common even in women of childbearing age.13 McCance and colleagues suggested that the inverse association between fetal growth and diabetes could be accounted for by an inverse association between genetic susceptibility to diabetes and mortality among low birthweight infants.13 Our results are not consistent with this explanation: when the men in this cohort were born in 1920-4 the infant mortality in Uppsala County was around 60 per 1000 live births, similar to the national rate for Sweden.14 Even if all these deaths had occurred in the lowest fifth of the ponderal index among infants who ...
Is sherry vinegar the same as sherry cooking wine? | Reference.comIs sherry vinegar the same as sherry cooking wine? | Reference.com
Cooking sherry and sherry vinegar, though both derived from the same fortified wine, are different products. While cooking sherry is a wine comparable to Madeira or Marsala, sherry vinegar is a...
5 Ways To Celebrate The Holidays As A Single Person | Sherry Gaba | YourTango5 Ways To Celebrate The Holidays As A Single Person | Sherry Gaba | YourTango
Sherry Gaba LCSW, Psychotherapist, Life & Recovery Coach is featured Celebrity Rehab on VH1. Sherry is the author of The Law of Sobriety which uses the law of attraction to recover from any addiction. Please download your free E books at sherrygaba.com Contact Sherry for webinars, teleseminars, coaching packages and speaking engagements. Listen to Sherry on A Moment of Change with Sherry Gaba on CBS Radio. Struggling with your own love junkie dramas? Youre not alone. Join my free newsletter community to get the support you need to stop the madness before it affects your next relationship or the one you are in now. - Get the Love You Truly Deserve! ...
Pitressin (Vasopressin): Uses, Dosage, Side Effects, Interactions, WarningPitressin (Vasopressin): Uses, Dosage, Side Effects, Interactions, Warning
Pitressin (Vasopressin) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources.
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We have previously shown that a significant inverse correlation exists between the height of the plasma insulin concentration and the efficiency of glucose uptake in the fasting state. Subsequently, we devised an infusion technic that provides a more specific measure of cellular resistance to insulin mediated glucose uptake. We have used this technic to study the relationship between fasting plasma insulin level and resistance to insulin mediated glucose uptake in twenty-two patients with normal oral glucose tolerance, fourteen patients with impaired glucose tolerance, and fourteen patients classified as having chemical diabetes mellitus. The results indicate a highly significant positive correlation between the degree of insulin resistance and fasting plasma insulin concentration (r = .69, p , .0001). A positive correlation (r = .43, p , .005) was also found between the degree of insulin resistance and the two hour plasma glucose level during an oral glucose tolerance test. However, no ...
Plasma c3 and c3a levels … - Göteborgs universitetPlasma c3 and c3a levels … - Göteborgs universitet
Background and Purpose: Inflammation seems to be a key player in the pathophysiology of stroke. In this study, we compared plasma C3 and C3a levels in cryptogenic and large-vessel disease (LVD) subtypes of ischemic stroke and control subjects and evaluated their association to outcome at 3 months and 2 years. Methods: C3 and C3a levels in plasma of 79 cryptogenic stroke and 73 LVD stroke patients, sampled within 10 days and at 3 months after stroke, and age- and sex-matched control subjects from the Sahlgrenska Academy Study on Ischemic Stroke were measured by ELISA. Functional outcome was assessed with the modified Rankin Scale. Results: Plasma C3 was increased in both stroke groups at both time points. Systemic elevation of C3a was limited to the acute phase in the cryptogenic stroke group, whereas plasma C3a levels in the LVD group were also elevated at the 3-month follow-up. In the LVD group, plasma C3 levels in the upper third at the 3-month follow-up were associated with an unfavorable ...
Sherry brands space tourism company Cosmica Spacelines - Design WeekSherry brands space tourism company Cosmica Spacelines - Design Week
Sherry has created the branding and visual identity for Cosmica Spacelines, a new space tourism company which gives people the opportunity to travel into space, and to buy shares in their own space plane.. The consultancy was appointed in November 2010, having been approached by the client because of Sherry managing director Celeste McNamaras previous work with another aerospace company.. Ellie Thompson, graphic designer at Sherry, says, They came to us with only a business plan and a name. They knew certain things they did and didnt want, then we were given free rein to explore the limits for the visual identity and the tone of voice.. Where lots of space companies focus on the technological side, Cosmica wanted to be about a spiritual, emotional experience.. The identity will be seen on business cards, the brochure, advertisements and the website. The brand marque uses an infinity symbol with a predominantly purple, white and silver palette to differentiate Cosmica from other space ...
A Cocktail to Remember: The (Very Likely) Love Story of Sherry and Agave | StarChefs.comA Cocktail to Remember: The (Very Likely) Love Story of Sherry and Agave | StarChefs.com
Some relationships, like Sadoians, are about pairing delicacies. Such is the case with The Grand Tour, his first-ever attempt at mixing tequila and Sherry that defied the Sherry-as-modifier trend and put the partially oxidized complexities of Amontillado at center stage. "Im more interested in delicate flavors and balance," says Sadoian. That delicacy might have been a liability when the Sherry "didnt have the backbone" to stand on its own, but a mere half ounce of Fortaleza reposado tequila came to the rescue. The reposado allowed Sadoian to add more aroma and flavor without losing the aperitif-level ABV or masking the contours of the Amontillado.. Relationships being what they are, theres also room for louder characters who keep each other in check. Just ask Star. She mixes La Frontera with none other than Palo Cortado, the unpredictable small production Sherry with a very big flavor profile. "Not only are many Palo Cortados expensive, theyre very complex," says Star. Palo Cortados begin ...
Restaurants tags Wined & Dined | Blogs / LJWorld.comRestaurants tags Wined & Dined | Blogs / LJWorld.com
We really liked how rich and raisiny it (the sherry) was, so we used that instead of a sweetening agent as a variation on the old fashioned," Hogue said. "Its rich, and sherry gives it a nice nutty nuance.". Admittedly, Im a sherry newbie (it turns out there are styles and levels of sweetness, just like champagne or German rieslings - who knew?). Baker kindly answered some questions this week to help bring me up to speed. Now, about those stereotypes.... Sara Shepherd: Convince me sherry is not just for people of the 1800s (or for soaking the spongecake in my grandmothers trifle recipe)? Ken Baker: Sherry has a long and storied history. Its a drink that travels well, and it has resilience. But the most important thing about it is that its super versatile - it has so many different flavors. Everybody identifies sherry with the sickly sweet after-dinner drink, but most of your best sherries are bone dry, umami-rich, very savory. Those are the kinds of wines that blow court out of the water, ...
Nehemiah: Overcoming Challenges - eBook: Bill Hybels, Kevin G. Harney, Sherry Harney: 9780310867425 - Christianbook.comNehemiah: Overcoming Challenges - eBook: Bill Hybels, Kevin G. Harney, Sherry Harney: 9780310867425 - Christianbook.com
Dynamic encounters with Gods Word, community-building opportunities, and life-changing applications are built into every session of the New Community small group Bible study guides. Challenging questions to answer during the week encourage you to reflect on Scripture and its impact on your life, both as an individual and as part of a community of Christ followers. The group time will then focus on applying the lessons to knowing, loving, serving and celebrating each other.The book of Nehemiah is a case study in overcoming lifes challenges. As you meditate on Nehemiahs story, you will discover the hope and victory that come when you walk in Gods wisdom through the challenges of life. 6 Sessions with Leaders Notes Nehemiah: Overcoming Challenges - eBook (9780310867425) by Bill Hybels, Kevin G. Harney, Sherry Harney
Breast Cancer Survivor | Sherry Vernelson | Vidant HealthBreast Cancer Survivor | Sherry Vernelson | Vidant Health
Vidant Health - When Sherry Vernelson found out that she had cancer, she decided right then and there to take charge. It wasnt going to get the best of her.
Dr. Sherry K Aujla, DO | Lansing, MI | Diagnostic Radiologist | VitalsDr. Sherry K Aujla, DO | Lansing, MI | Diagnostic Radiologist | Vitals
Dr. Sherry K Aujla, DO, rated 5/5 by patients. 1 reviews, Phone number & practice locations, Diagnostic Radiologist in Lansing, MI.
Charges dismissed in sherry enema death | ReutersCharges dismissed in sherry enema death | Reuters
Charges have been dropped against a Texas woman who was accused of giving her husband a sherry enema that killed him, the prosecutor in the case said on Wednesday.
Sherry Yang, AC - Berkeley, CA - Acupuncture | Healthgrades.comSherry Yang, AC - Berkeley, CA - Acupuncture | Healthgrades.com
Visit Healthgrades for information on Sherry Yang, AC Find Phone & Address information, medical practice history, affiliated hospitals and more.
Dr. Sherry Zox, MD - Bellefontaine, OH - Diagnostic Radiology | Healthgrades.comDr. Sherry Zox, MD - Bellefontaine, OH - Diagnostic Radiology | Healthgrades.com
Visit Healthgrades for information on Dr. Sherry Zox, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
Caol Ila 1997 - Managers Choice - Sherry Cask Scotch Whisky : The Whisky ExchangeCaol Ila 1997 - Managers' Choice - Sherry Cask Scotch Whisky : The Whisky Exchange
A single 1997 European Sherry Oak cask of Caol Ila chosen to represent the distillery in the cask strength Managers Choice range from Diageo. This is only the second ever single cask Caol Ila rel...
Animal Walk Americana Style by Sherry Holder HuntAnimal Walk Americana Style by Sherry Holder Hunt
Buy Animal Walk Americana Style art prints by Sherry Holder Hunt at Imagekind.com. Shop Thousands of Canvas and Framed Wall Art Prints and Posters at Imagekind.
Protecting your skin with sunscreen - Dr Sherry Ingraham of Advanced Dermatology & Skin CareProtecting your skin with sunscreen - Dr Sherry Ingraham of Advanced Dermatology & Skin Care
Dr. Sherry Ingraham of Advanced Dermatology speaks with KHOU TV Channel 11 about protecting yourself from sun damaged skin by protecting yourself with
Royal Lochnagar 1994 - Managers Choice - Sherry Cask Scotch Whisky : The Whisky ExchangeRoyal Lochnagar 1994 - Managers' Choice - Sherry Cask Scotch Whisky : The Whisky Exchange
A special Royal Lochnagar 1994 bottled in 2009 at full strength from a single European Sherry Oak cask for the Managers Choice range.
Sherry Ingraham, M.D. | Advanced Dermatology MDSherry Ingraham, M.D. | Advanced Dermatology MD
Advanced Dermatology provides medical, cosmetic, and surgical treatment plans for all skin conditions. Learn more about our employee, Sherry Ingraham, M.D..
The Poisoned Tree by Sherry Marie Gallagher (Paperback) - LuluThe Poisoned Tree by Sherry Marie Gallagher (Paperback) - Lulu
Buy The Poisoned Tree by Sherry Marie Gallagher (Paperback) online at Lulu. Visit the Lulu Marketplace for product details, ratings, and reviews.
Mothers in Medicine: (Sort of) Home cookinMothers in Medicine: (Sort of) Home cookin'
For non-frozen and quick - see campbellskitchen.com. You can pick by main ingredient, time of the day, and time to table. The recipe generally begins with one of their soups but then you dress it up with additions and seasoning. One of my sons favorites involves chicken breast - just brown it lightly. Remove from pan, make a sauce with cream of chicken soup and chopped red and green pepper add the chicken back and in a few minutes you are ready to go. pounding the chicken breasts first speeds it up and adding a little very dry sherry to the (any) sauce makes it a little more sophisticated. I generally keep a bottle of sherry in the fridge. If you do this, dont buy cheap cooking sherry. Buy the expensive stuff. It lasts forever at only 2 tablespoons per sauce. After all, all you want is the flavor.... ReplyDelete ...
Synonyms for adh | Synonym.comSynonyms for adh | Synonym.com
hormone secreted by the posterior pituitary gland (trade name Pitressin) and also by nerve endings in the hypothalamus; affects blood pressure by stimulating capillary muscles and reduces urine flow by affecting reabsorption of water by kidney tubules. ...
DiabeconDiabecon
... is used for patients suffering from non-insulin dependent diabetes, produced by Himalaya Herbal Healthcare - focused on producing and developing safe, natural and innovative remedies that ...
IP] Re: Yesterdays Endo Visit--A Tad ScaryIP] Re: Yesterday's Endo Visit--A Tad Scary
Sherry C wrote: ,,,My A1C was 6.3 and my blood pressure was okay-- 128/78 lying and 132/80 standing. but my albumin was 660.8 when normal is 0-29!!! Im not even exactly sure what this means. He started me on an ace inhibitor called Mavik (?). The doc said he will see me again in 3-4 months and we will redo the blood tests and maybe do a 24 hour urine test ,snip, what exactly is happening to the old kidneys? Should I stop drinking diet colas and only drink water? ,,, Sherry, It seems like we do everything were supposed to do, and still get blind-sided. I dont know why your endo wants to wait 3-4 months and *maybe* do a 24-hr urine test. The $ wont come out of his pocket, so get one NOW! Then, my usual *suggestion* is request a referral to a nephrologist. *If* this is to be of great concern, a kidneyologist is your best bet. Waiting, maybe-ing, and all that rot dont do one thing for you except keep you under your endos control. I dont know what is happening to the old kidneys, but kidney dz ...
sherry lansingsherry lansing
This website is intended for educational purposes only. The educational material contained in this website is based on interpretation of the scientific literature and the experience of the T.A. Sciences and Recharge Biomedical Clinic. Telomerase Activation is rapidly-evolving science and experts have differing views as to its benefits and safety. We urge each prospective client to become educated and consult their own experts prior to starting the PATTON PROTOCOL. Statements on this website have not been evaluated by the Food and Drug Administration ...
Cepa Vieja Sherry Vinegar - 16.9 ozCepa Vieja Sherry Vinegar - 16.9 oz
|p|The depth and complexity of the Vinagres de Yema is a result of the time honored tradition of utilizing the solera method of aging. The process begins with the harvest of Palomino grapes grown near Jerez, Spain, and a series of barr
Sherry rambling: March 2012Sherry rambling: March 2012
My friend is going to move in her new home, she has a home under renovation. She has interest to find suitable modern bathroom lighting. It is great to know she is moving in new home, I want to tell her that she can shop online. She is busy at work and dont have time to shop, she told me that when she finished her work it is late at night so the shops are already closed. She is particular about the lighting; she finds that some shops here are selling old style of lighting it is not up to her standard ...
Stay of Execution: A Rose By Any Other Name....Stay of Execution: A Rose By Any Other Name....
My name is Scheherazade. My nickname is Sherry. You can call me either one, I really do like both. Slight preference for Scheherazade, I guess, but I recognize that it is a mouthful at the very least. And everyone who knows me shortens it to Sherry pretty quickly, it seems, regardless of in what context they met me. Other nicknames that are approved, depending on who the speaker is and what your tone of voice is: Agent 2, Milkbone, Monkey, Shaniqua, Shibber, Schehera, Shee-hair-bear, and Sher. Also Z. Of course Sweetness and Cutest and Sugarplum and other such diminutives are...
History of Aquavit. (English language). - Nesodden Akevittens VennerHistory of Aquavit. (English language). - Nesodden Akevittens Venner
For two centuries Norwegian ships have transported Linie aquavit in sherry casks around the world. The duration of the sea passage; the ships constant, regular rolling; the changing temperatures and sea air - all these enhance and balance the aroma of aquavit. Nesodden akevittens venner, Nesodden,akevitt,nesoddakevitten
Pick your Battles and Go for it! » This Time I Mean ItPick your Battles and Go for it! » This Time I Mean It
I ate a bagel and a banana about an hour before we started (I googled it beforehand to see what we should eat.) As my daughter and I watched some of the other participants come across the finish line from an earlier heat, they were covered in mud and looking pretty exhausted. I wondered if I could do this, I had succeeded in losing forty pounds during the past year and this was a pact my daughter and I had made to keep us on track for her upcoming wedding. As our ten o clock start time approached we were branded with our wristbands, time chips around our ankles and numbers written on our arms. It was an atmosphere filled with camaraderie and anticipation. We signed the waiver forms releasing the sponsors of any liability if we got hurt.. Two hundred runners were corralled into a gated area as the minutes counted down to race time. As we mingled and talked to others in our horde I met a few other first timers, I was beginning to get some of my confidence back. We took the barbarian oath and ...
Springbank 15 Years - Whisky.comSpringbank 15 Years - Whisky.com
This new Springbank expression was almost sold out shortly after it had been launched. The high percentage of sherry casks conjures up memories of the old bottlings.
TolbutamideTolbutamide
AntidiureticAntidiuretic
SulfonylureaSulfonylurea
Glossary of diabetesGlossary of diabetes
Herb-drug interactionsHerb-drug interactions
Aldehyde dehydrogenase 3 family, member A1Aldehyde dehydrogenase 3 family, member A1
Tall Man letteringTall Man lettering
AspirinAspirin
Anti-diabetic medicationAnti-diabetic medication
List of MeSH codes (D02)List of MeSH codes (D02)
Disulfiram-like drugDisulfiram-like drug
OrexigenicOrexigenic
Syndrome of inappropriate antidiuretic hormone secretionSyndrome of inappropriate antidiuretic hormone secretion
AllopurinolAllopurinol
DisulfiramDisulfiram
ATC code A10ATC code A10
List of drugs: Cf-ChList of drugs: Cf-Ch
List of causes of hypoglycemiaList of causes of hypoglycemia
Elevated alkaline phosphataseElevated alkaline phosphatase
Sulfonamide (medicine)Sulfonamide (medicine)
List of drugs: Df-DiList of drugs: Df-Di
ChlorpropamideChlorpropamide
LamotrigineLamotrigine
DomperidoneDomperidone
DihydropyridineDihydropyridine
GlisoxepideGlisoxepide
CarbamazepineCarbamazepine
Inward-rectifier potassium channelInward-rectifier potassium channel
PhenibutPhenibut
BepridilBepridil
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceHealth Care
ChlorpropamideFlushingDemeclocyclineSuppositoriesChlorothiazideDiabetes InsipidusErythemaTolbutamideBlood GlucoseSulfonylurea CompoundsElectronic MailDiabetes Mellitus, Type 1Food Dispensers, AutomaticDiabetes MellitusDiabetes Mellitus, Type 2Postal ServiceInternetInsulinHypoglycemic AgentsGlucoseHypoglycemiaUltraviolet RaysDNA RepairCentrifugation, IsopycnicCricetinaeDNA DamageCHO CellsUnconsciousnessTabletsCandyPatient Acceptance of Health CareAgropyronNesidioblastosisPathology, ClinicalPancreatic DiseasesHyperinsulinismPancreatectomyPoison Control CentersPoisoningInformation CentersGas PoisoningNational Health Planning Information Center (U.S.)Poisons
Chlorpropamide (discontinued in the UK)Chlorpropamide (discontinued in the UK)
Chlorpropamide - DrugBankChlorpropamide - DrugBank
Chlorpropamide inhibition of excision repair and postreplication repair of ultraviolet damage in Chinese hamster ovary cellsChlorpropamide inhibition of excision repair and postreplication repair of ultraviolet damage in Chinese hamster ovary cells
Chlorpropamide tabletsChlorpropamide tablets
United Kingdom prospective diabetes study (UKPDS) 13: relative efficacy of randomly allocated diet, sulphonylurea, insulin, or...United Kingdom prospective diabetes study (UKPDS) 13: relative efficacy of randomly allocated diet, sulphonylurea, insulin, or...
Chlorpropamide-alcohol flushing, malar thermal circulation ind...Chlorpropamide-alcohol flushing, malar thermal circulation ind...
Chlorpropamide tablets | UCLA Health Library, Los Angeles, CAChlorpropamide tablets | UCLA Health Library, Los Angeles, CA
Chlorpropamide | 101 Ways to Save Money on Health CareChlorpropamide | 101 Ways to Save Money on Health Care
Chlorpropamide | Daviss Drug Guide for Rehabilitation Professionals | F.A. Davis PT Collection | McGraw-Hill MedicalChlorpropamide | Davis's Drug Guide for Rehabilitation Professionals | F.A. Davis PT Collection | McGraw-Hill Medical
Ferring pharmaceuticals inc evokes constant talking of many viewers, in fact basically as a result of chlorpropamideFerring pharmaceuticals inc evokes constant talking of many viewers, in fact basically as a result of chlorpropamide
Chromatographic studies of chlorpropamide interactions with normal and glycated human serum albumin based on affinity...Chromatographic studies of chlorpropamide interactions with normal and glycated human serum albumin based on affinity...
ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes<...ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes<...
Rejunex CD3 Tablet in Hindi (रिजुनेक्स सी डी 3 टैबलेट) - परस्पर प्रभाव - Intas Pharma - - India | all4insure.ruRejunex CD3 Tablet in Hindi (रिजुनेक्स सी डी 3 टैबलेट) - परस्पर प्रभाव - Intas Pharma - - India | all4insure.ru
Pharmacophore An International Research Journal: AbstractPharmacophore An International Research Journal: Abstract
Chlorpropamide - WikipediaChlorpropamide - Wikipedia
Chlorpropamide: MedlinePlus Drug InformationChlorpropamide: MedlinePlus Drug Information
Common and Rare Side Effects for Chlorpropamide OralCommon and Rare Side Effects for Chlorpropamide Oral
Jaundice and Rash Associated with Chlorpropamide | Diabetes CareJaundice and Rash Associated with Chlorpropamide | Diabetes Care
ChlorpropamideChlorpropamide
Chlorpropamide and Sudal-12 Chewable Drug Interactions - Drugs.comChlorpropamide and Sudal-12 Chewable Drug Interactions - Drugs.com
Chlorpropamide and CPM-PSE DM Drops Drug Interactions - Drugs.comChlorpropamide and CPM-PSE DM Drops Drug Interactions - Drugs.com
Chlorpropamide | definition of chlorpropamide by Medical dictionaryChlorpropamide | definition of chlorpropamide by Medical dictionary
Roles of chlorpropamide, alcohol and acetaldehyde in determining the chlorpropamide-alcohol flush. - PubMed - NCBIRoles of chlorpropamide, alcohol and acetaldehyde in determining the chlorpropamide-alcohol flush. - PubMed - NCBI
Apo-Chlorpropamide - Uses, Side Effects, Interactions - MedBroadcast.comApo-Chlorpropamide - Uses, Side Effects, Interactions - MedBroadcast.com
Chlorpropamide tablets - AHealthyMe - Blue Cross Blue Shield of MassachusettsChlorpropamide tablets - AHealthyMe - Blue Cross Blue Shield of Massachusetts
94-20-2 - Chlorpropamide - 1-(4-Chlorobenzenesulfonyl)-3-n-propylurea - J64110 - Alfa Aesar94-20-2 - Chlorpropamide - 1-(4-Chlorobenzenesulfonyl)-3-n-propylurea - J64110 - Alfa Aesar
Diabinese, Insulase (Chlorpropamide) | Weight ManagementDiabinese, Insulase (Chlorpropamide) | Weight Management
Hyperinsulinaemic hypoglycaemia due to chlorpropamide-induced nesidioblastosis. | Journal of Clinical PathologyHyperinsulinaemic hypoglycaemia due to chlorpropamide-induced nesidioblastosis. | Journal of Clinical Pathology
Employment of acetaminophen in cosmetics area wins apo chlorpropamide tab 100mgEmployment of acetaminophen in cosmetics area wins apo chlorpropamide tab 100mg
Chlorpropamide treatment restores the reduced carrageenan-induced paw edema and pleural exudate volume in diabetic rats |...Chlorpropamide treatment restores the reduced carrageenan-induced paw edema and pleural exudate volume in diabetic rats |...
Chlorpropamide -- Teratogenic Agent Symptoms, Diagnosis, Treatments and Causes - RightDiagnosis.comChlorpropamide -- Teratogenic Agent Symptoms, Diagnosis, Treatments and Causes - RightDiagnosis.com
Effects of Vernonia Amygdalina and Chlorpropamide on Blood Glucose [Med J Islamic World Acad Sci]Effects of Vernonia Amygdalina and Chlorpropamide on Blood Glucose [Med J Islamic World Acad Sci]
ChlorpropamideChlorpropamide
Chlorpropamide tabletsChlorpropamide tablets
Chlorpropamide)? - ????? ????????? ??????? 999Chlorpropamide)? - ????? ????????? ??????? 999
Tolbutamide - WikipediaTolbutamide - Wikipedia
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceHealth Care
ChlorpropamideFlushingDemeclocyclineSuppositoriesChlorothiazideDiabetes InsipidusErythemaTolbutamideBlood GlucoseSulfonylurea CompoundsElectronic MailDiabetes Mellitus, Type 1Food Dispensers, AutomaticDiabetes MellitusDiabetes Mellitus, Type 2Postal ServiceInternetInsulinHypoglycemic AgentsGlucoseHypoglycemiaUltraviolet RaysDNA RepairCentrifugation, IsopycnicCricetinaeDNA DamageCHO CellsUnconsciousnessTabletsCandyPatient Acceptance of Health CareAgropyronNesidioblastosisPathology, ClinicalPancreatic DiseasesHyperinsulinismPancreatectomyPoison Control CentersPoisoningInformation CentersGas PoisoningNational Health Planning Information Center (U.S.)Poisons
GlibenclamideGlyburideInsulinAldehyde DehydrogenaseCPAFDiabetesPatientsTabletsMechanismDrugOral hypogTypeRiskMedicalYearsNormalDiabineseGlipizideTolazamideSulfonylureasSulfonylureaDavis's Drug GuideTeratogenic AgentHypoglycemicSulphonylureaAntidiabetic drugInhibitionDiabetes insipidusAllergicChlorpromazine100mgDesmopressinCitationTabletDiabeticDoseDrugsHypoglycemiaSymptomsAlcoholMechanismTreatmentBlood sugarSide Effects
Glibenclamide1
Glyburide1
Insulin3
Aldehyde Dehydrogenase1
  • A mechanism of CPAF has been regarded as the inhibition of aldehyde dehydrogenase 2 (ALDH2) by an N 1 -alkyl-substituted derivative of chlorpropamide, and the expression of these mutations of ALDH2 and alcohol dehydrogenase 2 (ADH2) could determine the alcohol tolerance among the Japanese population. (elsevier.com)
CPAF3
Diabetes3
  • Chlorpropamide is a first line option for treating type 2 diabetes in people who are not overweight, or who cannot take metformin. (netdoctor.co.uk)
  • High performance affinity chromatography and affinity microcolumns containing immobilized HSA were used to investigate binding by the sulfonylurea drug chlorpropamide to normal HSA and glycated HSA, which is a modified form of HSA that has an increased serum concentration in diabetes. (elsevier.com)
  • Experiments employing frontal analysis indicated that the binding by chlorpropamide gave a good fit to a two-site model for both normal HSA and glycated HSA samples that were representative of controlled or advanced diabetes. (elsevier.com)
Patients1
  • These results suggest that chlorpropamide inhibition of repair processes may potentiate the effects of known mutagenic hazards and may also be responsible for the increased incidence of chromosome aberrations in patients treated with the drug. (nih.gov)
Tablets1
Mechanism2
Drug1
  • Chlorpropamide gave a larger 1.4- to over 1.5-fold increase at Sudlow site II when the affinity of this drug was compared between normal HSA and the same samples of glycated HSA. (elsevier.com)
Oral hypog1
  • Chlorpropamide, an oral hypoglycemic agent, was tested for effects on excision repair and postreplication repair of ultraviolet (UV) damage of DNA in CHO-K1 cells. (nih.gov)
Type1
Risk1
  • Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy (UKPDS-33). (drugbank.ca)
Medical1
  • Journal of the American Medical Organization: "Factitious Hypoglycemia Because Of Chlorpropamide: Record of an Instance, with Professional Similarity to an Islet Cell Growth of the Pancreatic. (ecoraces.net)
Years1
  • pfizer inc. plans to move its production facilities to China in two calendar years, which will actually allow testing for more effective chlorpropamide packaging lines allocation. (thevenus.net)
Normal1
  • The affinity of chlorpropamide at Sudlow site I had a small increase of up to 1.2-fold when comparing the normal HSA and glycated HSA samples. (elsevier.com)
Diabinese9
  • Diabinese (chlorpropamide) is a less commonly used medicine for lowering blood sugar, but it can cause low blood sugar levels so always carry some form of sugar with you that can be readily used. (iodine.com)
  • Diabinese (chlorpropamide) is effective at controlling blood sugar and A1c levels.It is an oral medicine and a good alternative for those who don't like injections. (iodine.com)
  • Diabinese (chlorpropamide) is available as a cheaper, generic form. (iodine.com)
  • Diabinese (chlorpropamide) can cause blood sugar levels to be low. (iodine.com)
  • While taking Diabinese (chlorpropamide), your blood sugars should be checked regularly. (iodine.com)
  • Diabinese (chlorpropamide) can lose its effectiveness over time. (iodine.com)
  • Diabinese (chlorpropamide) stimulates your body to release more insulin, which lowers the amount of sugar in your blood and reduces damage to vital organs. (iodine.com)
  • Medicines that lower blood sugar similarly to Diabinese (chlorpropamide) can increase your risk of death from heart problems when compared to other methods of controlling blood sugar, specifically with diet alone or diet and insulin. (iodine.com)
  • Talk to your doctor about the risk and benefits of taking Diabinese (chlorpropamide) to decide if it is the right medicine for you. (iodine.com)
Glipizide4
Tolazamide1
Sulfonylureas5
Sulfonylurea4
Davis's Drug Guide2
Teratogenic Agent3
Hypoglycemic3
Sulphonylurea1
Antidiabetic drug1
  • There is evidence to indicate that exposure to Chlorpropamide (an antidiabetic drug) during pregnancy may have a teratogenic effect on the fetus. (rightdiagnosis.com)
Inhibition2
  • The present results support the view that CPAF is associated with elevated blood acetaldehyde levels due to inhibition of aldehyde dehydrogenase by chlorpropamide. (nih.gov)
  • These results suggest that chlorpropamide inhibition of repair processes may potentiate the effects of known mutagenic hazards and may also be responsible for the increased incidence of chromosome aberrations in patients treated with the drug. (nih.gov)
Diabetes insipidus1
Allergic1
Chlorpromazine1
  • One patient died and another developed serious symptoms after receiving 750 mg of chlorpropamide instead of 75 mg of chlorpromazine daily. (ismp.org)
100mg2
Desmopressin1
  • Previously untreated DI patients may be given intranasal or subcutaneous desmopressin or oral chlorpropamide (adults only) for 2 or 3 days. (clinicaltrials.gov)
Citation1
  • citation needed] Chlorpropamide is a white crystalline powder with no characteristic taste or smell. (wikipedia.org)
Tablet1
Diabetic5
  • Pseudoephedrine may interfere with blood glucose control and reduce the effectiveness of chlorproPAMIDE and other diabetic medications. (drugs.com)
  • Knowing that hyperglycemia is a hallmark of vascular dysfunction in diabetes and that neonatal streptozotocin-induced diabetic rats (n-STZ) present reduced inflammatory response, we decided to evaluate the effect of chlorpropamide-lowered blood glucose levels on carrageenan-induced rat paw edema and pleural exudate in n-STZ. (springer.com)
  • n-STZ diabetic rats were treated with chlorpropamide (200mg/kg, 15d, by gavage) 8 weeks after STZ injection. (springer.com)
  • Chlorpropamide treatment by restoring β-cell function, reducing blood sugar levels, and improving glucose tolerance might be contributing to the correction of the reduced inflammatory response tested as paw edema and pleural exudate in n-STZ diabetic rats. (springer.com)
  • Its blood-glucose-lowering potential in both normoglycemic and alloxan-induced diabetic male Sprague-Dawley rats compared favourably to that of chlorpropamide. (medicaljournal-ias.org)
Dose2
Drugs1
  • Drugs.com: Chlorpropamide Fitzgerald, M.G. (1962). (wikipedia.org)
Hypoglycemia1
  • Chlorpropamide has appreciably more side-effects, mainly because of its very prolonged duration of action and the consequent hazard of hypoglycemia and it should no longer be used. (bionity.com)
Symptoms1
  • Less common side effects of chlorpropamide include gastrointestinal symptoms such as nausea, vomiting, and diarrhea. (wikipedia.org)
Alcohol5
  • Roles of chlorpropamide, alcohol and acetaldehyde in determining the chlorpropamide-alcohol flush. (nih.gov)
  • After smaller alcohol challenges (with chlorpropamide pretreatment) there were positive intercorrelations between flush-score, rise in facial skin temperature, and plasma concentrations of chlorpropamide and blood acetaldehyde. (nih.gov)
  • Chlorpropamide-alcohol flushing: a dominantly inherited trait associated with diabetes. (alfa.com)
  • Chlorpropamide-alcohol flushing, malar thermal circulation ind. (mysciencework.com)
  • Chlorpropamide-alcohol flushing, malar thermal circulation index, and baseline malar temperature. (mysciencework.com)
Mechanism2
  • Mechanism of chlorpropamide-induced antidiuresis in man: Evidence for release of ADH and enhancement of peripheral action. (alfa.com)
  • There time was, however, no significant linguistic difference between the responses observed mechanism for chlorpropamide versus fenofibrate at discouraging any time. (thevenus.net)
Treatment4
Blood sugar3
Side Effects2
United Kingdom prospective diabetes study (UKPDS) 13: relative efficacy of randomly allocated diet, sulphonylurea, insulin, or...
United Kingdom prospective diabetes study (UKPDS) 13: relative efficacy of randomly allocated diet, sulphonylurea, insulin, or... (bmj.com)
Chlorpropamide (discontinued in the UK)
Chlorpropamide (discontinued in the UK) (netdoctor.co.uk)
Chlorpropamide tablets
Chlorpropamide tablets (healthlibrary.brighamandwomens.org)
Chlorpropamide | 101 Ways to Save Money on Health Care
Chlorpropamide | 101 Ways to Save Money on Health Care (101waystosavemoneyonhealthcare.info)
ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes<...
ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes<... (keio.pure.elsevier.com)
Pharmacophore An International Research Journal: Abstract
Pharmacophore An International Research Journal: Abstract (pharmacophorejournal.com)
Which medications in the drug class Sulfonylureas are used in the treatment of Glucose Intolerance?
Which medications in the drug class Sulfonylureas are used in the treatment of Glucose Intolerance? (medscape.com)
Aloprim (allopurinol) Injection for Gout and Kidney Stones: Uses, Dosage, Side Effects, Interactions, Warnings
Aloprim (allopurinol) Injection for Gout and Kidney Stones: Uses, Dosage, Side Effects, Interactions, Warnings (rxlist.com)
List of drugs/medicine used for Type 2 Diabetes (Diabetes - Type 2 , Non-Insulin-Dependent Diabetes Mellitus (NIDDM) , Adult...
List of drugs/medicine used for Type 2 Diabetes (Diabetes - Type 2 , Non-Insulin-Dependent Diabetes Mellitus (NIDDM) , Adult... (medindia.net)
94-20-2 - Chlorpropamide - 1-(4-Chlorobenzenesulfonyl)-3-n-propylurea - J64110 - Alfa Aesar
94-20-2 - Chlorpropamide - 1-(4-Chlorobenzenesulfonyl)-3-n-propylurea - J64110 - Alfa Aesar (alfa.com)
Chlorpropamide: MedlinePlus Drug Information
Chlorpropamide: MedlinePlus Drug Information (medlineplus.gov)
Oral hypoglycemics overdose: MedlinePlus Medical Encyclopedia
Oral hypoglycemics overdose: MedlinePlus Medical Encyclopedia (medlineplus.gov)
Orphenadrine, aspirin, and caffeine Advanced Patient Information - Drugs.com
Orphenadrine, aspirin, and caffeine Advanced Patient Information - Drugs.com (drugs.com)
Tranylcypromine (Oral Route) Before Using - Mayo Clinic
Tranylcypromine (Oral Route) Before Using - Mayo Clinic (mayoclinic.org)
Eldepryl Oral Advanced Patient Information - Drugs.com
Eldepryl Oral Advanced Patient Information - Drugs.com (drugs.com)
Nortriptyline: Side Effects, Dosage, Uses, and More
Nortriptyline: Side Effects, Dosage, Uses, and More (healthline.com)
Incretin-based Drugs and Pancreatic Cancer - Full Text View - ClinicalTrials.gov
Incretin-based Drugs and Pancreatic Cancer - Full Text View - ClinicalTrials.gov (clinicaltrials.gov)
Tamiflu (oseltamivir): uses and side effects
Tamiflu (oseltamivir): uses and side effects (netdoctor.co.uk)
Pitressin (Vasopressin): Uses, Dosage, Side Effects, Interactions, Warning
Pitressin (Vasopressin): Uses, Dosage, Side Effects, Interactions, Warning (rxlist.com)
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List of Common Diabetes Medications (healthline.com)
Type 2 Diabetes Drugs Linked to Higher Cardiovascular Risk | HealthCentral
Type 2 Diabetes Drugs Linked to Higher Cardiovascular Risk | HealthCentral (healthcentral.com)
Diabinese - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
Diabinese - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki (rxwiki.com)
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Orange juice, 17 topics (medicalook.com)