A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
A class of histamine receptors discriminated by their pharmacology and mode of action. Most histamine H1 receptors operate through the inositol phosphate/diacylglycerol second messenger system. Among the many responses mediated by these receptors are smooth muscle contraction, increased vascular permeability, hormone release, and cerebral glyconeogenesis. (From Biochem Soc Trans 1992 Feb;20(1):122-5)
Compounds containing phenyl-1-butanone.
A histamine H1 antagonist. It is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies.
Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only.
Histamine H1 antagonist used in allergic rhinitis; ASTHMA; and URTICARIA. It is a component of COUGH and COLD medicines. It may cause drowsiness.
An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate ADENYLYL CYCLASES. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5)
A histamine H2 receptor agonist that is often used to study the activity of histamine and its receptors.
A histamine H2 receptor antagonist that is used as an anti-ulcer agent.
Cell-surface proteins that bind histamine and trigger intracellular changes influencing the behavior of cells. Histamine receptors are widespread in the central nervous system and in peripheral tissues. Three types have been recognized and designated H1, H2, and H3. They differ in pharmacology, distribution, and mode of action.
An antagonist of histamine that appears to block both H2 and H3 histamine receptors. It has been used in the treatment of ulcers.
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
A histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
Histamine substituted in any position with one or more methyl groups. Many of these are agonists for the H1, H2, or both histamine receptors.
Drugs that bind to and activate histamine receptors. Although they have been suggested for a variety of clinical applications histamine agonists have so far been more widely used in research than therapeutically.
A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
A highly potent and specific histamine H2 receptor agonist. It has been used diagnostically as a gastric secretion indicator.
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The concept concerned with all aspects of providing and distributing health services to a patient population.
A systematic collection of factual data pertaining to health and disease in a human population within a given geographic area.
The state wherein the person is well adjusted.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Organizations which provide an environment encouraging social interactions through group activities or individual relationships especially for the purpose of rehabilitating or supporting patients, individuals with common health problems, or the elderly. They include therapeutic social clubs.
A form of therapy in which two or more patients participate under the guidance of one or more psychotherapists for the purpose of treating emotional disturbances, social maladjustments, and psychotic states.
Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)
An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here.
A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Devices designed to provide personal protection against injury to individuals exposed to hazards in industry, sports, aviation, or daily activities.
A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
A sympathomimetic that acts mainly by causing release of NOREPINEPHRINE but also has direct agonist activity at some adrenergic receptors. It is most commonly used as a nasal vasoconstrictor and an appetite depressant.
Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)
A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
Narcotic analgesic related to CODEINE, but more potent and more addicting by weight. It is used also as cough suppressant.
A traditional grouping of drugs said to have a soothing or calming effect on mood, thought, or behavior. Included here are the ANTI-ANXIETY AGENTS (minor tranquilizers), ANTIMANIC AGENTS, and the ANTIPSYCHOTIC AGENTS (major tranquilizers). These drugs act by different mechanisms and are used for different therapeutic purposes.
A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414)
Use of plants or herbs to treat diseases or to alleviate pain.
Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
Sequential operating programs and data which instruct the functioning of a digital computer.

Transport characteristics of diphenhydramine in human intestinal epithelial Caco-2 cells: contribution of pH-dependent transport system. (1/137)

Transport characteristics of diphenhydramine, an antihistamine, were studied in cultured human intestinal Caco-2 cell monolayers to elucidate the mechanisms of its intestinal absorption. Diphenhydramine accumulation in the monolayers increased rapidly and was influenced by extracellular pH (pH 7.4 > 6.5 > 5.5). Diphenhydramine uptake was temperature dependent, saturable, and not potential sensitive. Kinetic analysis revealed that the apparent Km values were constant (0.8-1.0 mM) in all pH conditions tested, whereas Vmax values decreased at the lower pH. The initial uptake of diphenhydramine was competitively inhibited by another antihistamine, chlorpheniramine, with a Ki value of 1.3 mM. On the other hand, cimetidine and tetraethylammonium, typical substrates for the renal organic cation transport system, had no effect. Moreover, biological amines and neurotransmitters, such as histamine, dopamine, serotonin, and choline, also had no effect on the diphenhydramine accumulation. Finally, diphenhydramine uptake was stimulated by preloading monolayers with chlorpheniramine (trans-stimulation effect). These findings indicate that diphenhydramine transport in Caco-2 cells is mediated by a specific transport system. This pH-dependent transport system may contribute to the intestinal absorption of diphenhydramine.  (+info)

Nalpha-methyl histamine and histamine stimulate gastrin release from rabbit G-cells via histamine H2-receptors. (2/137)

BACKGROUND: Gastrin release by Helicobacter pylori may be an important step in the pathway leading to duodenal ulceration. A histamine H3-receptor agonist was found to release gastrin from antral mucosal fragments; this was interpreted as being due to suppression of somatostatin release. H. pylori is reported to produce Nalpha-methyl histamine (NalphaMH), which is an agonist of H3 as well as other histamine receptors. H. pylori infection also recruits mast cells, which release histamine. AIM: To determine the direct effects of histamine receptor agonists on isolated gastrin cells. METHODS: Rabbit G-cells were prepared by countercurrent elutriation and cultured on 24-well plates. RESULTS: NalphaMH (10-6-10-4 M) caused a dose-dependent increase in gastrin release from a basal level of 2.3 +/- 0.2% total cell content (TCC; mean +/- S.E.M.) to a maximum of 5.1 +/- 0.7%, an increase of 117% (P < 0. 005) above basal. This was abolished by the H2-antagonist ranitidine (10-5 M), but not by immunoblockade with anti-somatostatin antibody, the H1-antagonist chlorpheniramine (10-5 M) or the H3-antagonist thioperamide (10-4 M). The histamine H2-receptor agonist dimaprit (10-6-10-4 M) increased gastrin release from 2.4 +/- 0.2% to 3.6 +/- 0.2% TCC (P < 0.001). Gastrin release was also stimulated by histamine (10-7-10-4 M) from a basal value of 3.0 +/- 0.3% to 5.4 +/- 0.5% TCC (P < 0.001). This also was inhibited by ranitidine (10-5 M) (P < 0.01). CONCLUSION: NalphaMH and histamine release gastrin from G-cells via H2-receptors; this might contribute to H. pylori-associated hypergastrinaemia.  (+info)

Interferon treatment of chronic hepatitis C in patients cured of pediatric malignancies. (3/137)

BACKGROUND AND OBJECTIVE: Chronic hepatitis C was a frequent complication in patients treated for malignancy until the introduction of anti-HCV screening tests for blood donors. The association between chronic hepatitis C and progression to cirrhosis and hepatocellular carcinoma has been reported in about 20% and 5% of patients, respectively, within 20-30 years of infection. In adult patients, interferon has proved to be effective in decreasing the abnormal values of transaminases and the level of HCV viremia. Our purpose was to assess efficacy of and tolerance to interferon in a group of young patients who had acquired HCV infection during a period of chemotherapy. DESIGN AND METHODS: Interferon-a (IFN) was administered to 26 adolescents and young adults (13 males, age range 17-36 years; median age 24) with chronic hepatitis C, including 4 with hepatitis B virus co-infection, who had been treated for leukemia or solid tumor 5 to 19 years before joining this trial. Patients were treated with natural IFN alpha at a dose of 4 MU/m(2) thrice weekly for 12 months and followed up for another 6 months thereafter. RESULTS: Nine patients stopped treatment during the first 6 months because of side effects (2 cases) or lack of response. At the end of the trial, 8 (31%) cases had responded, with alanine amino-transferase normalization and clearance of hepatitis C virus (HCV) RNA. A sustained response was only documented in 15% of cases, however, irrespective of any hepatitis B virus co-infection. The 2 patients with HCV genotype 2 were both responders, whereas only 8% of those with genotype 1 responded. INTERPRETATION AND CONCLUSIONS: These data show that the efficacy of IFN in this series of young patients is similar to that reported for otherwise healthy adults with hepatitis C. Patients with genotype 2 are strong candidates for IFN treatment while other therapeutic strategies should be designed for patients with HCV genotype 1.  (+info)

Bronchial vasodilation evoked by increased lower airway osmolarity in dogs. (4/137)

Hyperosmotic saline solutions stimulate lower airway sensory nerves. To determine whether airway hyperosmolarity evokes neurally mediated changes in bronchial artery blood flow (Qbr), we measured the effect of injection of small volumes (1 ml) of hyperosmotic saline into a right lobar bronchus on Qbr of anesthetized, artificially ventilated dogs. In 14 dogs, hyperosmotic saline (1,200 and 2,400 mmol/l) increased Qbr by 58 +/- 12 (SE) and 118 +/- 12%, respectively, from a baseline of 8 +/- 2 ml/min. Qbr increased within 6-8 s of the injections, peaked at 20 s, and returned to control over 2-3 min. Isosmotic saline had minimal effects. In contrast, hyperosmotic saline decreased flow in an intercostal artery that did not supply the airways. The bronchial vasodilation was decreased by 72 +/- 11% after combined blockade of alpha-adrenoceptors and muscarinic cholinergic receptors and by 66 +/- 6% when the cervical vagus nerves were cooled to 0 degrees C. Blockade of H(1) and H(2) histamine receptors did not reduce the nonvagal response. We conclude that hyperosmolarity of the lower airways evokes bronchial vasodilation by both a centrally mediated reflex that includes cholinergic and adrenergic efferent pathways and by unidentified local mechanisms.  (+info)

Functional neuroimaging of cognition impaired by a classical antihistamine, d-chlorpheniramine. (5/137)

Antihistamine induced cognitive decline was evaluated using positron emission tomography (PET) measurement of histamine H1 receptor (H1R) occupancy and regional cerebral blood flow (rCBF). Cognitive performance in attention-demanding task deteriorated dose-dependently and the effects were statistically significant after the treatment of 2 mg of d-chlorpheniramine. There was no significant change in subjective sleepiness in the same dose. The regional blockade of H1R was observed mainly in the frontal, temporal and anterior cingulate cortices, and the intravenous administration of d-chlorpheniramine as a therapeutic dose (2 mg) blocked over 60% of H1R in the frontal cortices. The results from activation study using visual discrimination tasks demonstrated that enhanced activity in the right prefrontal and anterior cingulate cortices as well as a decreased activity in the left temporal and frontal cortices and midbrain after the treatment of d-chlorpheniramine. There were no changes in global CBF for the subjects treated with 2 mg d-chlorpheniramine (pre; 44.8+/-3.3 ml dl(-1) min(-1) vs post; 44.4+/-4.7 ml dl(-1) min(-1)). The results indicated that the attention system of human brain could be altered by therapeutic doses of H1R antagonists. These findings provide the information as to the potential risk of antihistamines in our daily activities. British Journal of Pharmacology (2000) 129, 115 - 123  (+info)

Involvement of tyrosine phosphorylation in the positive inotropic effect produced by H(1)-receptors with histamine in guinea-pig left atrium. (6/137)

We investigated the effect of stimulation of H(1)-receptors with histamine on protein tyrosine phosphorylation levels in guinea-pig left atrium and evaluated the influences of tyrosine kinase inhibitors on the positive inotropic effect mediated by H(1)-receptors in this tissue. Histamine induced an increase in tyrosine phosphorylation in four main clusters of proteins with apparent molecular weights of 25, 35, 65 and 150 kDa. Tyrosine phosphorylation of these proteins attained a peak around 2 - 3 min following histamine stimulation and then declined to or below basal levels. Histamine-induced protein tyrosine phosphorylation was antagonized by the H(1)-receptor antagonists mepyramine (1 microM) and chlorpheniramine (1 microM), but not by the H(2)-receptor antagonist cimetidine (10 microM). The positive inotropic effect of histamine was depressed in a concentration-dependent manner by the tyrosine kinase inhibitors tyrphostin A25 (50 to 100 microM) and genistein (10 to 50 microM) but not by the inactive genistein analogue daidzein (50 microM). The positive inotropic effect of isoprenaline was unchanged by tyrphostin A25 and genistein. At a concentration of 1 microM histamine produced a dual-component positive inotropic response composed of an initial increasing phase and a second and late developing, greater positive inotropic phase. Treatment with tyrphostin A25 (100 microM) and genistein (50 microM), but not daidzein (50 microM), significantly attenuated the two components of the inotropic response, although genistein suppressed the initial component more markedly than the late component. We conclude that increased protein tyrosine phosphorylation may play an important role in initiating at least some part of the positive inotropic effect of H(1)-receptor stimulation in guinea-pig left atrium.  (+info)

Cardiovascular effects of histamine administered intracerebroventricularly in critical haemorrhagic hypotension in rats. (7/137)

The study was designed to determine the cardiovascular effects of histamine administered intracerebroventricularly (icv) in a rat model of volume-controlled haemorrhagic shock. The withdrawal of approximately 50% of total blood volume resulted in the death of all control saline icv treated animals within 30 min. Icv injection of histamine produced a prompt dose-dependent (0.1-100 nmol) and long-lasting (10-100 nmol) increase in mean arterial pressure (MAP), pulse pressure (PP) and heart rate (HR), with a 100% survival of 2h after treatment (100 nmol). The increase in MAP and HR after histamine administration in bled rats in comparison to the normovolaemic animals was 2.7-3.3- and 1.3-3.6-fold higher, respectively. Pretreatment with chlorpheniramine (50 nmol icv), H1 receptor antagonist, inhibited the increase in MAP, PP, HR and survival rate produced by histamine, while chlorpheniramine given alone had no effect. Neither ranitidine (50 nmol icv), H2 histamine receptor antagonist, nor thioperamide (50 nmol icv), H3 receptor blocker, influenced the histamine action, however, when given alone, both evoked the pressor effect with elongation of survival time. It can be concluded that histamine administered icv reverses the haemorrhagic shock conditions, and histamine H1 receptors are involved.  (+info)

Painless thyroiditis induced by the cessation of betamethasone. (8/137)

We describe the first reported case of painless thyroiditis induced by an abrupt cessation of betamethasone. A 53-year-old woman experienced transient thyrotoxicosis after the abrupt cessation of celestamine, a mixture of betamethasone and chlorpheniramine. Since neither TSH receptor- nor thyroid stimulating-antibodies were negative, and thyroid scintigram did not show the thyroid gland, she was diagnosed as having painless thyroiditis. Fourteen months after the onset of thyrotoxicosis, serum TSH was detectable without hypothyroidism. We speculate that reduction in betamethasone may be one of the triggers of painless thyroiditis.  (+info)

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Abstract: The method of choice for analysis of drugs in multi-component preparations is chromatographic based technique such as High Performance Liquid Chromatography (HPLC). However, chromatographic method is time consuming and requiring much effort. As a consequence, some simple methods such as UV spectrophotometry are continuously developed, especially in combination with the chemometrics software. The UV-vis spectrophotometry coupled with multivariate calibration of Partial Least Square (PLS) has been developed for quantitative analysis of paracetamol, guaiphenesin and chlopheniramine maleate in the presence of phenylpropanolamine without separation step. The calibration model is prepared by developing a series of sample mixture comprising these drugs in certain proportion. The evaluation of calibration model was based on coefficient of determination (R2) and Root Mean Square Error of Calibration (RMSEC). The result showed that UV spectrophotometry combined with PLS can be used for ...
a) Extendryl SR Extended-Release Capsules (chlorpheniramine maleate 8mg/phenylephrine HCL 20 mg/methscopolamine nitrate 2.5mg), in 100 capsules. NDC #0256-0111-01; b) Extendryl JR Extended-Release Capsules (chlorpheniramine maleate 5mg/phenylephrine HCL 10 mg/methscopolamine nitrate 1.25 mg), in 100 capsule bottles. NDC #0256-0177-01. Both products are Rx for the relief of respiratory congestion, allergic rhinitis, vasomotor rhinitis, and allergic skin reactions of urticaria and angioedema. Recall #D-091/092-9. CODE ...
I used to buy these at Sams Club, in a 2 pack of bottles with 150 caplets in each. I need to know if there is anywhere else I can get them packaged that way, or it least 1 bottle. In lieu of that, where can I buy them in the largest quantity? Per my Doctors approval, I have to take them 3
Warfarin Sodium: Warfarin Sodium Amorphous: Warfarin Sodium Clathrate: X: Xanthan: Xantinol Nicotinate: Xipamide: Xylazine HCL: Xylitol. Shake well before using Learn about drug interactions between amitriptyline-chlordiazepoxide oral and methscopolamine oral and use the RxList drug interaction checker to check drug combinations The study is based on chlorpheniramine maleate and hydroxychloroquine sulfate (the active ingredients of Chlorpheniramine maleate and Hydroxychloroquine sulfate, respectively), and Chlorpheniramine maleate and Hydroxychloroquine sulfate (the brand names). Sanoski. Methylcobalamin 250mcg + Folic Acid 500mcg/5ml Syrup 19. It lists the capsules and tablets that are official in the United States Pharmacopeia and indicates the relevant tight (T), well-closed (W), and light-resistant (LR. 238. 172. Chlordiazepoxide / methscopolamine alcohol/food interactions. A to Z drug monographs from Facts & Comparisons; includes additional patient education materials and drug interactions. ...
In the present study, we have shown that both cetirizine 10 mg and chlorpheniramine 4 mg increased P300 latencies significantly compared with baseline. Only been a few studies have examined the effect of antihistamines on P300 latency in children.24,25 None, to our knowledge, has studied the sedative effect of cetirizine in atopic children using P300 latency. Compared with many other objective tests of CNS function, it has the advantages of being relatively simple; rapid; and less affected by practice, motivation, or boredom.20,21 It is an objective measure that is suitable for use in children and that has been used extensively to study the cognitive effects of antihistamines and other medication.21 Prolongation of P300 latency is taken as an index of impaired cognitive function.6. The inclusion of chlorpheniramine as the positive control in our study was not to draw direct comparisons with cetirizine but to ensure sensitivity.6 Chlorpheniramine 4 mg has been shown to increase P300 latency ...
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Houston, TX (SafetyAlerts) - The Food and Drug Administration (FDA) today reported that Great Southern Laboratories (GSL) is recalling Cyndal HD Cough Syrup because of subpotency of the phenylephrine (50%) due to incorrect weight addition in batch production. The recalled Cyndal HD Cough Syrup (Hydrocodone Bitartrate 1.57mg/ Phenylephrine Hydrochloride 5mg/Chlorpheniramine Maleate 2mg), was sold in 16 fluid ounce (NDC 60258-703-16) and 1 gallon (NDC 60258-703-28) containers. According to FDA, 118 gallon bottles and 7,032 pint bottles were distributed in the Southeastern United States.. The recalled vials can be identified by the Lot Number 91949.. This ongoing Class III recall was initiated by GSL by verbal communication on December 15, 1999, followed by letters dated December 21 and 30, 1999. This is the first public notice issued by the FDA.. Questions concerning this recall may be directed to the FDA at 1-888-INFO-FDA ...
Manufacturer of ANTI COLD TABLET - Ambroxol HCL 30mg Guaiphensin 50mg Levosulbutamol 1mg syrup, Dextromethorphan Hbr 10mg Phenylephrine Hbr 5mg Chlorpheniramine Maleate 5mg Menthol 1mg, Levocetirizine Dihydrochloride 5mg and Montelukast Sodium 10mg Levocetrizine 5mg offered by SNU Biocare, Panchkula, Haryana.
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best methods of treatment of allergic rhinitis, that is the most usual, is the usage of classic antihistaminic drugs [such asChlorpheniramine], but their side effects, specially somnolence and malaise, made a few patients to discontinue such treatment. More than a decade has showed that the Non Sedating Anti Histaminic Drugs [Terfenadin, Astemizole andLoratadine] are free from these side effects and do not show the CNS and anticholinergic disorders. The evaluation of their efficacy in the epidemiology of IRAN, beside the comparison of generic products with the registrated ones, is the main goal of this research. In this clinical study, the efficacy and adverse reactions of the Loratadine and its registratedproduct called Claritin are compared with Chlorpheniramine on 90 patients. It has been performed in northeast IRANand the study is a kind of double blind, prospective studies.30 patients have received Chlorpheniramine, as the same for Loratadine and Claritin. Then the results are compared with ...
TY - JOUR. T1 - High-affinity binding of [3H]doxepin to histamine H1-receptors in rat brain. T2 - Possible identification of a subclass of histamine H1-receptors. AU - Taylor, John E.. AU - Richelson, Elliott. PY - 1982/3/12. Y1 - 1982/3/12. N2 - The binding of the radioactively labeled tricyclic antidepressant, [3H]doxepin, to rat brain tissie was examined. Scatchard plots of specific [3H]doxepin binding indicated the presence of two distinct binding sites. The equilibrium dissociation constant (KD) of the high-affinity site was 0.020 nM with a maximal binding capacity (Bmax) of 13.7 fmol/mg protein. The corresponding values for the low-affinity site were 3.6 nM and 740 fmol/mg protein, respectively. The high-affinity site was sensitive to competition by pharmacologically relevant concentrations of histamine H1 antagonists such as pyrilamine (KD = 1.0 nM), diphenhydramine (KD = 20 nM), d-chlorpheniramine (KD = 1.7 nM), and 1-chlorpheniramine (KD = 97 nM). The Bmax for [3H]doxepin binding in the ...
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Let your doctor know if you have pain, nasal congestion, or cough that gets worse or lasts for more than 7 days. Call your doctor if you have a fever that gets worse or lasts for more than 3 days. If you have a cough that lasts more than 2 days, if your cough comes back, or if it occurs with a fever, rash, headache, nausea, or vomiting see your doctor.. You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.. ...
What is Poly-Tussin (Chlorpheniramine/Hydrocodone/Phenylephrine)? Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Hydrocodone is a narcotic. It is a pain reliever and a … Read more →. ...
To evaluate just how much exposure the participants had to anticholinergic drugs, the researchers used computer records in the drugstores that dispensed them.. From the drugstore data the participants added up all of the normal daily doses and worked out the accumulative anticholinergic vulnerability for every participant within the previous 10 years.. Within the length of the research, almost 800 participants developed dementia.. The outcomes revealed the most frequently used drugs were tricyclic antidepressants ( for instance, doxepin or Sinequan), first-generation antihistamines (chlorpheniramine, Chlor Trimeton), and antimuscarinics for bladder management (oxybutynin, Ditropan).. The researchers estimated that individuals taking at least 10 milligrams daily of doxepin, 4 milligrams per day of chlorpheniramine, or 5 milligrams daily of oxybutynin for at least three years would be at greater danger of developing dementia.. But while there are very few options to oxybutynin for increasing ...
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This study evaluate the efficacy and safety of experimental drug The study was designed to evaluate the efficacy and safety of fixed combinations Decongex® Plus Syrup and Decongex® Plus Oral Solution (consisting of brompheniramine maleate and phenylephrine hydrochloride) compared to Resfenol® Oral Solution (paracetamol, maleate chlorpheniramine and phenylephrine hydrochloride) in the treatment of nasal congestion and rhinorrhea present in acute attacks of viral rhinitis (common cold) and allergic. This study population will consist in participants of both sexes, aged between 6 to 11 years old with acute inflammatory condition of the upper airways, defined as nasal congestion and runny nose, with no less than 24 (twenty four) hours and a maximum of 48 (forty-eight) hours prior to inclusion ...
This study evaluate the efficacy and safety of experimental drug The study was designed to evaluate the efficacy and safety of fixed combinations Decongex® Plus Syrup and Decongex® Plus Oral Solution (consisting of brompheniramine maleate and phenylephrine hydrochloride) compared to Resfenol® Oral Solution (paracetamol, maleate chlorpheniramine and phenylephrine hydrochloride) in the treatment of nasal congestion and rhinorrhea present in acute attacks of viral rhinitis (common cold) and allergic. This study population will consist in participants of both sexes, aged between 6 to 11 years old with acute inflammatory condition of the upper airways, defined as nasal congestion and runny nose, with no less than 24 (twenty four) hours and a maximum of 48 (forty-eight) hours prior to inclusion ...
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
This study aimed at validating an analytical method, using the accuracy profile approach, for the assay of chlorphenamine maleate by capillary electrophoresis. The validation was done using concentrations ranging between 75% and 125% of the target concentration of 600 mg/ml. Validation standards were prepared separately in triplicate for each series. Studied validation criteria were selectivity, linearity, trueness, precision (repeatability and intermediate precision), accuracy and limits of detection and quantification. The method was selective, with recoveries ranging between 99.55% and 99.84%. The relative standard deviations of repeatability and intermediate precision were <5%. The accuracy profile confirmed the performance of the assay method between 75% and 100% of the target concentration of 600 mg/ml. The detection and quantification limits were 5 mg/l and 15 mg/l respectively. This ecological and economical method was applied to identify and quantify chlorphenamine maleate in 3 samples of
In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Chlorpheniramine, is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose ...
Foeniculum vulgare (fennel) has been widely used in traditional medicine for treatment of variousdiseases including pediatric colic. This study was designed to assess the antinociceptive effects of aqueousextract of F. vulgare on visceral pain and possible involvement of opioidergic, serotonergic, adrenergic andhistaminergic systems. The results of this study showed that aqueous extract of F. vulgare (50, 100 and 200mg/kg, IP) induces antinociceptive effects (Pcimetidine significantly attenuate this effect (from 71.9% to 21.6%, PP=0.003, respectively). Furthermore, chlorpheniramine and cimetidine significantly decreased onset of first abdominal writhing (latency) in comparison with extract (Pphentolamine had no effect on antinociception and the latency induced by F. vulgare. The ED50 value for antinociceptive effects of extract was 87.6 mg/kg. These results suggest that antinociceptive effects of F. vulgare are partially mediated by histamine H1 and H2 receptors.
You may use medicine daily for quick relief of symptoms that occur suddenly or are getting worse. Or you may use it in advance if you know you may breathe an allergen. For example, if you have severe pollen allergies, your doctor may suggest that you start using a corticosteroid spray 1 to 2 weeks before the pollen season starts.. You may want to think about using different medicines at different times of the day. For example, during the day you could use a nondrowsy antihistamine such as fexofenadine (such as Allegra) or loratadine (such as Claritin). But if you are at home in the evening and sleepiness is not a concern, you can think about using an antihistamine like diphenhydramine (Benadryl) or chlorpheniramine (Chlor-Trimeton). These are less expensive but can make you feel sleepy. You may also try a combination of medicines to relieve all of your symptoms. Talk with your doctor about which symptoms are most important for you to treat and which medicines may work best for you. For worse ...
Histamine, norepinephrine and KCl each evoke contractile responses in isolated guinea-pig mesenteric artery. However, only the contractile response to histamine was characterized by acute desensitization or tachyphylaxis. The tachyphylaxis observed to histamine was independent of the time interval between successive administrations up to at least 1 hr. The histamine H1-receptor blocker, chlorpheniramine (10(-9) M), completely inhibited contractile responses to histamine (10(-5) M). In contrast, metiamide (10(-4) M), an H2-receptor blocker, potentiated contractions which were characterized by tachyphylaxis. Propranolol (10(-6) M), phentolamine (10(-6) M) and atropine (10(-6) M) affected neither the contractile response itself nor the tachyphylaxis to histamine (10(-5) M). Indomethacin (10(-5) M) and aspirin (3 X 10(-4) M) potentiated the initial contraction induced by histamine (10(-5) M) and completely abolished the tachyphylaxis. The response to the initial application of histamine (10(-5) M) ...
BREMERTON, WASHINGTON--A county coroner has changed the cause of Kristina Shannons death from acute overdose to undetermined after independent experts reviewed the case and the state of Washington threatened to take him to court. Kitsap County Coroner Greg Sandstrom had originally accepted the opinion of forensic pathologist Emmanuel Lacsina, that Shannon, 29, had 5 1/2 times the normal amount of the antihistamine chlorpheniramine in her system when she suddenly died on July 2, 2005. Her father, Denny Shannon, said his daughter had autism and intellectual disabilities, and could not have taken the drug on her own. Officials with the Department of Social and Health Services objected to the Sandstroms initial ruling and ordered a separate investigation, saying that the coroners report did not match medical records kept by staff at Frances Haddon Morgan Center, the institution where Shannon had stayed for 20 years. They hired outside consultants who investigated Shannons death and reportedly ...
The anti-epileptic drug Keppra® (levetiracetam) reached net sales of EUR 460 million which is 1% lower than last year due to further post-patent expiry erosion in North America (-21%) and the divestment of smaller emerging markets to GlaxoSmithKline (GSK) in the first quarter of 2009 which was compensated by extended market leadership in Europe (+12%) and an increase of 4% in Rest of World. Zyrtec® (cetirizine), for allergy, had reduced net sales of 12% to EUR 150 million due to the divestment to GSK. European sales remained stable, whilst Japanese sales increased by 4% through the successful launch of paediatric indications and new formulations. Xyzal® (levocetirizine), for allergy, reached net sales of EUR 63 million (-23%) following entry of generic competition in the European market. Tussionex™ (hydrocodone polistirex and chlorpheniramine polistirex) made net sales of EUR 45 million (-33%) after a market shift to codeine-based products combined with a weak cough and cold season in the ...
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cephalexin with no prescription to purchase the willingness to regularly and objectively monitor your condition is the test of your level of self- chlorpheniramine and Iotadien are also used to heal the patches. order cephalexin sample pack Knowing what to look for and what illnesses need to be dismissed by your doctor will help with this process. Though the field of ASCs is not marred by controversies, Most especially if the illness offers a variety of methods and every type are effective. and if you do not have the money or the commitment to join come hair club ...
DM COUGH AND COLD LIQUID CHERRY FLAVOUR is a specialty drug on the Reformulary and can be used to treat . Check with your doctor if there are other medications you can take before taking this drug.
3.0.co;2-5. Carter, S. J.; Cassaday, H. J. (1998). "State-Dependent Retrieval and Chlorpheniramine". Human ...
... is an analog of chlorpheniramine. The only difference is that the chlorine atom in the benzene ring is replaced ... chlorpheniramine, dexchlorpheniramine (Polaramine), triprolidine (Actifed), and iodopheniramine. The halogenated alkylamine ...
Active ingredients include dextromethorphan, pseudoephedrine and chlorpheniramine. The combination of antihistamine, de- ...
... is the INN while chlorpheniramine is the USAN and former BAN. Yasuda SU, Wellstein A, Likhari P, Barbey JT, ... Hellbom, E. (2006). "Chlorpheniramine, selective serotonin-reuptake inhibitors (SSRIs) and over-the-counter (OTC) treatment". ... Chlorphenamine (also known as chlorpheniramine, CP, or CPM) is a first-generation antihistamine used in the prevention of the ... Miyata S, Hirano S, Ohsawa M, Kamei J (2011). "Chlorpheniramine exerts anxiolytic-like effects and activates prefrontal 5-HT ...
Chlorpheniramine plasma concentration and histamine H1-receptor occupancy. Clin Pharmacol Ther 1995;58:210-20. Gendreau-Reid L ...
"State-Dependent Retrieval and Chlorpheniramine". Human Psychopharmacological Clinical Experiment. 13 (7): 513-523. doi:10.1002 ...
It is the pharmacologically active dextrorotatory isomer of chlorpheniramine. Dexchlorpheniramine is an antihistamine, or an ...
Alcohol IP 8 mg Chlorpheniramine Maleate IP 4 mg Codeine Phosphate IP 10 mg Carmoisine and Sunset Chlorpheniramine maleate, an ... Its active ingredients are chlorpheniramine maleate and codeine phosphate. Each 5 ml of Corex Cough Syrup contains: ...
Antihistamines such as diphenhydramine and chlorpheniramine are commonly used as treatment. People treated with H1 ...
It is also able to transform the antihistamines brompheniramine, chlorpheniramine and pheniramine. It forms a glucoside with ... chlorpheniramine, and pheniramine toN-oxide andN-demethylated metabolites by the fungusCunninghamella elegans". Xenobiotica. 25 ...
Another danger is chlorpheniramine's notably long half life (about a whole day), which may result in high levels of it building ... Chlorpheniramine is an anticholinergic that can cause very serious reactions in high doses.[vague][citation needed] This may be ... and chlorpheniramine maleate (an antihistamine). Varieties of Coricidin may also contain acetaminophen (an analgesic/ ... Chlorpheniramine Dextromethorphan "Coricidin HBP Cough and Cold", WebMD. Retrieved 7 January 2017. Henigig, Christian. Missing ...
Hellbom E (2006). "Chlorpheniramine, selective serotonin-reuptake inhibitors (SSRIs) and over-the-counter (OTC) treatment". Med ...
Hellbom E (2006). "Chlorpheniramine, selective serotonin-reuptake inhibitors (SSRIs) and over-the-counter (OTC) treatment". Med ... some clinically used drugs such as chlorpheniramine, dextromethorphan, and methadone possess SRI properties secondarily to ... Chlorpheniramine (Chlor-Trimeton) Dextromethorphan (DXM; Robitussin) Dextropropoxyphene (Darvon) Dimenhydrinate (Dramamine) ...
However, in practice, hydroxyzine is rarely as efficacious as the benzodiazepines.[citation needed] Chlorpheniramine (Chlor- ... Miyata, Shigeo; Hirano, Shoko; Ohsawa, Masahiro; Kamei, Junzo (2009). "Chlorpheniramine exerts anxiolytic-like effects and ...
A form that contains dextromethorphan, pseudoephedrine, acetaminophen, and chlorpheniramine, is sold as Cotylenol. As of 2017, ... chlorpheniramine and phenylephrine. The brand was introduced in 1955 by McNeil Laboratories, a family owned pharmaceutical ...
... is also present in various cough syrups as codeine phosphate including chlorpheniramine maleate. Pure codeine is also ... chlorpheniramine (2 mg) and codeine (9.5 mg). Preparations containing pure codeine (e.g., codeine phosphate tablets or codeine ...
Examples of common anticholinergics: Antimuscarinic agents Atropine Benztropine (Cogentin) Biperiden Chlorpheniramine (Chlor- ... hydrocodone polistirex/chlorpheniramine). However, it is noted that opioid/antihistamine combinations are used clinically for ...
Chlorpheniramine (maleate) Chlorpheniramine is an antihistamine found in various children's cough and cold syrups. ...
"Factitious Urticaria (dermographism): Treatment by Cimetidine and Chlorpheniramine in a Randomized Double-blind Study." Br J ...
Yasuda SU, Yasuda RP (1999). "Affinities of brompheniramine, chlorpheniramine, and terfenadine at the five human muscarinic ...
Short courses of sedative antihistamines such as chlorpheniramine may be useful in alleviating the itch. Fever during treatment ...
... chlorpheniramine (Chlor-Trimeton), and brompheniramine (Dimetane). However, a 1955 study of "antihistaminic drugs for colds," ... Chlorpheniramine (Chlor-Trimeton) Dimenhydrinate (Dramamine, Gravol) - combination of diphenhydramine and 8-chlorotheophylline ...
Multi-symptom cold medicines contain other active ingredients, such as paracetamol (acetaminophen), chlorpheniramine, and ... this brand presents a danger when used at recreational doses due to the presence of chlorpheniramine. In over-the-counter ...
Both products contained chlorpheniramine maleate (an antihistamine) and phenylpropanolamine hydrochloride (a decongestant) but ... Both products contained 75 mg of phenylpropanolamine hydrochloride, but Cold Capsule IV contained 12 mg chlorpheniramine ...
Hellbom, E. (2006). "Chlorpheniramine, selective serotonin-reuptake inhibitors (SSRIs) and over-the-counter (OTC) treatment". ... Chlorpheniramine synthesis 1: D. Papa, E. Schwenk, N. Sperber, Templat:US Patent (1951). ... Chlorpheniramine synthesis 2: D. Papa, E. Schwenk, N. Sperber, Templat:US Patent (1954). ... Miyata S, Hirano S, Ohsawa M, Kamei J (2011). "Chlorpheniramine exerts anxiolytic-like effects and activates prefrontal 5-HT ...
... and chlorpheniramine. Prednazoline Prednimustine J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical ...
Antihistamines (first-generation) (e.g., brompheniramine, buclizine, captodiame, chlorphenamine (chlorpheniramine), cinnarizine ... hydrocodone polistirex/chlorpheniramine). However, it is noted that opioid/antihistamine combinations are used clinically for ...
Sometimes a third active ingredient, such as ascorbic acid, caffeine, chlorpheniramine maleate, or guaifenesin is added to this ...
... effect of its dextromethorphan is hazardous because it also contains chlorpheniramine. Citalopram F. v. Bruchhausen, G. ...
... cetirizine and chlorpheniramine. They do not prevent the discharge of histamine, but it has been proven that they do prevent a ...
Ask questions and get answers about Chlorpheniramine. Our support group helps people share their own experience. 26 questions, ... Chlorpheniramine Patient Information at Drugs.com. *Chlorpheniramine Information for Consumers. *Chlorpheniramine Information ... Home › Q & A › Support Groups › Chlorpheniramine. Join the Chlorpheniramine group to help and get support from people like ... Chlorpheniramine/methscopolamine. Can medicine with chlorpheniramine help inner ear problems?. Posted 26 Jun 2017 • 0 answers ...
Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce ... What is chlorpheniramine and phenylephrine?. Chlorpheniramine is an antihistamine that reduces the effects of natural chemical ... What is the most important information I should know about chlorpheniramine and phenylephrine?. Do not use this medicine if you ... It is not known whether chlorpheniramine and phenylephrine will harm an unborn baby. Do not use this medicine without your ...
Chlorpheniramine) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related ... home drugs a-z list side effects drug center ana-kit (epinephrine, chlorpheniramine) drug ...
CHLORPHENIRAMINE MALEATE (UNII: V1Q0O9OJ9Z) (CHLORPHENIRAMINE - UNII:3U6IO1965U) CHLORPHENIRAMINE MALEATE. 2 mg in 6000 mg. ... Acetaminophen 100 MG / Chlorpheniramine Maleate 2 MG Oral Capsule. SCD. 3. 1437775. APAP 100 MG / Chlorpheniramine Maleate 2 MG ... acetaminophen 100 MG / chlorpheniramine maleate 2 MG Oral Capsule. PSN. 2. 1437775. ... 999 COLD REMEDY- acetaminophen, chlorpheniramine maleate, caffeine capsule. To receive this label RSS feed. Copy the URL below ...
Allermin Forte information about active ingredients, pharmaceutical forms and doses by Synco, Allermin Forte indications, usages and related health products lists
Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce ... FDA pregnancy category B. Chlorpheniramine is not expected to harm an unborn baby. Do not use this medicine without your ... Chlorpheniramine may pass into breast milk and may harm a nursing baby. Antihistamines may also slow breast milk production. Do ... Chlorpheniramine is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the ...
Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce ... What is chlorpheniramine and pseudoephedrine?. Chlorpheniramine is an antihistamine that reduces the effects of natural ... It is not known whether chlorpheniramine and pseudoephedrine will harm an unborn baby. Do not use this medicine without your ... Chlorpheniramine and pseudoephedrine is a combination medicine used to treat symptoms of the common cold or seasonal allergies ...
Get the best prices on Chlorpheniramine antihistamines for allergic reactions in pets and people today from Vet Depot. No ... Chlorpheniramine Active Ingredient (per tablet): Chlorpheniramine maleate 4 mg. Chlorpheniramine Inactive Ingredients: D&C ... Chlorpheniramine is not FDA-approved for use in cats and dogs; however, it is a common veterinary practice to use it off-label ... Chlorpheniramine is an antihistamine for pets and people that is used to treat allergic reactions from snake bites, vaccination ...
No problems requiring medical attention have been observed in infants of mothers taking chlorpheniramine (Ito 1993, Paton 1985 ... Chlorpheniramine. Full Record Display. 2017 Full text (in our servers) *Ball H, Blair PS. (For UNICEF UK). Caring for your baby ... Chlorpheniramine Maleate is also known as Chlorphenamine. Here it is a list of alternative known names:: * ... Rino Dexa™. Contains other elements than Chlorpheniramine Maleate in its composition *Rinogan™. Contains other elements than ...
... chlorpheniramine maleate, dextromethorphan hbr tablet, film coated) can come in different packaging based on the dosage and ...
Chlorpheniramine is an antihistamine used for acute inflammatory and allergic conditions: snake bites, vaccination reactions, ... Antihistamines such as chlorpheniramine maleate may be helpful given long term. Chlorpheniramine maleate has a strong anti- ... Chlorpheniramine Maleate. Chlorpheniramine Maleate Anti-allergy Tablets have several important effects and thus several uses. ... Chlorpheniramine maleate causes drowsiness in animals just as it does in people and can be used as a mild tranquilizer. Some ...
Abuse of "BRON": a Japanese OTC cough suppressant solution containing methylephedrine, codeine, caffeine and chlorpheniramine. ... and chlorpheniramine. 2. Major psychiatric symptoms observed included hallucinatory-paranoid state and affective disorder. ...
The aim of the present study was to fabricate a thermosensitive gel containing chlorpheniramine maleate (CPM)-loaded ... Chitosan Nanoparticles In situ gel Chlorpheniramine maleate Poloxamer 407 This is a preview of subscription content, log in to ... Formulation and stability study of chlorpheniramine maleate nasal gel. Pharm Dev Technol. 2010;15(5):484-91.CrossRefGoogle ... Taş C, Ozkan Y, Savaşer A, Baykara T. In vitro and ex vivo permeation studies of chlorpheniramine maleate gels prepared by ...
Chlor-Trimeton Chlorpheniramine Maleate Antihistamine, 12 Hour, Tablets - 24ea Chlorpheniramne Maleate/Antihistamine. ... TITLE: Chlor-Trimeton Chlorpheniramine Maleate Antihistamine, 12 Hour, Tablets - 24ea. Chlorpheniramne Maleate/Antihistamine. ... Active Ingredient (per Tablet): Chlorpheniramine Maleate (12 mg). Inactive Ingredients: Acacia, Butylparaben, Calcium Phosphate ...
Chlorpheniramine polistirex equivalent to 8 mg of chlorpheniramine maleate and hydrocodone polistirex equivalent to 10 mg of ... Drug: Chlorpheniramine polistirex equivalent to 8 mg of chlorpheniramine maleate and hydrocodone polistirex equivalent to 10 mg ... Drug: Chlorpheniramine polistirex equivalent to 8 mg of chlorpheniramine maleate and hydrocodone polistirex equivalent to 10 mg ... Drug: 5 mL chlorpheniramine (8 mg/5 mL)/hydrocodone (10 mg/5 mL) extended release oral suspension Tussionex® Pennkinetic® ...
Chlorpheniramine/pseudoephedrine (By mouth). Chlorpheniramine (klor-fen-IR-a-meen), Pseudoephedrine (soo-doe-e-FED-rin). Treats ... You should not use this medicine if you have had an allergic reaction to chlorpheniramine, or pseudoephedrine. You should not ...
Simultaneous Determination of Paracetamol, Guaiphenesin and Chlorpheniramine Maleate Using Ultraviolet Spectroscopy in ...
... is an antihistamine used in many prescription and over-the-counter drugs. This eMedTV segment ... What Is Chlorpheniramine Maleate?. Chlorpheniramine maleate is an antihistamine medication used as an active ingredient in many ... Chlorpheniramine Maleate. Chlorpheniramine maleate is an active ingredient found in many prescription medications and over-the- ... Chlorpheniramine maleate is one of the two most common forms of the medication (the other is chlorpheniramine tannate). ...
Are you looking for info on chlorpheniramine? This eMedTV Web page is for you. We provide basic information on what this drug ... Click Chlorpheniramine for more information on this medication, including how it works, what to do if you are pregnant or ... Chlorpheniramine comes in tablet, capsule, and liquid form. It is taken by mouth every 4 to 12 hours, depending on the ... Chlorpheniramine is an active ingredient in many different products. This medicine is an antihistamine, so you will often find ...
Antihistamines such as diphenhydramine and chlorpheniramine are commonly used as treatment. People treated with H1 ...
Other agents which have been shown to reverse chloroquine resistance in malaria are chlorpheniramine, gefitinib, imatinib, ...

No data available that match "chlorpheniramine"


  • How often can you take chlorpheniramine maleate 4mg + phenylephrine hcl 10mg? (drugs.com)
  • The generic name of Good Sense Cold is acetaminophen, chlorpheniramine maleate, dextromethorphan hbr, phenylephrine hcl. (ndclist.com)
  • Our product range includes a wide range of chlorpheniramine maleate 20mg injection, amoxycillin 3gm, sulbactum 1.5 gm (with 20 ml swfi) injection, amoxycillin 2gm and sulbactam 1gm injection (vet), ceftrixaone 3gm (with 10 ml swfi) injection, ivermectin 10mg injection and meloxicam & paracetamol injection 30ml. (bestpcdcompany.com)
  • Trumac Healthcare is one of the leading Chlorpheniramine Maleate Menthol Paracetamol Acetaminophen Phenylephrine Suspension Manufacturers Suppliers all over India. (trumachealthcare.net)
  • This is a combination of four medicines: Chlorpheniramine Maleate, Menthol, Paracetamol/Acetaminophen and Phenylephrine which relieve cold symptoms. (trumachealthcare.net)
  • Apart from Chlorpheniramine Maleate Menthol Paracetamol Acetaminophen Phenylephrine Suspension Manufacturers Suppliers, we at Trumac Healthcare provide range of other products across several divisions. (trumachealthcare.net)
  • 44473 blue pill Acetaminophen - Dextromethorphan HBr - Phenylephrine HCI - Chlorpheniramine Maleate long oval, blue, numbers 44-473 on them, it says it has 325 mg of acetaminophen in them.2 pills per dose ## found celoph. (medschat.com)
  • Chlorpheniramine/methscopolamine. (drugs.com)
  • What is the brand name for Levocloperastine fendizoate and chlorpheniramine maleate syrup in india? (drugs.com)
  • Manufacturer of a wide range of products which include dextromethrophan hbr 10mg chlorpheniramine maeate 2mg syrup and desloratadine hcl 2.5 mg ambroxol hcl 30 mg guiaphenesin 50 mg menthol 1 mg syrup. (lifestylebiosciencedermacare.com)
  • Antihistamines such as chlorpheniramine maleate may be helpful given long term. (medi-vet.com)
  • It is not known whether chlorpheniramine and phenylephrine will harm an unborn baby. (cigna.com)
  • Chlorpheniramine maleate causes drowsiness in animals just as it does in people and can be used as a mild tranquilizer. (medi-vet.com)
  • Chlorpheniramine Maleate Anti-allergy Tablets have several important effects and thus several uses. (medi-vet.com)
  • Chlorpheniramine is an antihistamine for pets and people that is used to treat allergic reactions from snake bites, vaccination reactions, atopic dermatitis, atopy, and more. (vetdepot.com)
  • Chlorpheniramine and phenylephrine is a combination medicine used to treat symptoms of the common cold or seasonal allergies, including sneezing, runny or stuffy nose, and itchy, watery eyes. (cigna.com)
  • Chlorpheniramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. (ndclist.com)
  • Chlorpheniramine Maleate is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. (trumachealthcare.net)
  • FDA pregnancy category B. Chlorpheniramine is not expected to harm an unborn baby. (everydayhealth.com)
  • Do not use in animals with a hypersensitivity to chlorpheniramine or similar medications. (vetdepot.com)
  • Chlorpheniramine maleate should not be used with additional tranquilizing medications. (medi-vet.com)
  • The objective of this open-label, randomized, two-period, crossover study was to evaluate the oral bioavailability of the Mallinckrodt extended release test capsule formulation of chlorpheniramine polistirex/hydrocodone polistirex compared to an equivalent oral dose of a commercially available extended release oral suspension of chlorpheniramine polistirex/hydrocodone polistirex (Tussionex® Pennkinetic® Extended Release Oral Suspension, Celltech Pharmaceuticals, Inc.) in a test group of healthy subjects under fasting conditions. (clinicaltrials.gov)
  • 1. The paper describes the mental disturbances of 44 abusive cases of "BRON," an over-the-counter (OTC) cough suppressant solution containing methylephedrine, codeine, caffeine, and chlorpheniramine. (amphetamines.com)
  • Where can I buy chlorpheniramine maleate time release capsules 8mg. (drugs.com)
  • Chlorpheniramine is used for reactions to vaccinations and blood transfusions, insect bites and stings, snakebites, to soothe itchy skin, and for a variety of other related purposes. (vetdepot.com)
  • Drinking alcohol can increase certain side effects of chlorpheniramine. (everydayhealth.com)
  • Chlorpheniramine maleate has a strong anti-nausea side effect, which makes it helpful in treating motion sickness. (medi-vet.com)
  • The aim of the present study was to fabricate a thermosensitive gel containing chlorpheniramine maleate (CPM)-loaded nanoparticles following intranasal administration for effective treatment of allergic rhinitis. (springer.com)
  • Can I take Amoxicillin with Acetaminophen, Chlorpheniramine Maleate, Phenylephrine? (drugs.com)
  • Chlorpheniramine/Phenylephrine - does chlorpheniramine make you drowsy? (drugs.com)
  • I took a tylenol sinus rapid release gel at 930am can I take a Chlorpheniramine/Phenylephrine now? (drugs.com)
  • How often can you take chlorpheniramine maleate 4mg + phenylephrine hcl 10mg? (drugs.com)
  • Can I take phenylephrine and chlorpheniramine maleate together? (drugs.com)
  • What is the most important information I should know about chlorpheniramine and phenylephrine? (rexhealth.com)
  • Chlorpheniramine and phenylephrine is a combination medicine used to treat symptoms of the common cold or seasonal allergies, including sneezing, runny or stuffy nose, and itchy, watery eyes. (rexhealth.com)
  • Chlorpheniramine and phenylephrine may also be used for purposes not listed in this medication guide. (rexhealth.com)
  • What should I discuss with my healthcare provider before taking chlorpheniramine and phenylephrine? (rexhealth.com)
  • You should not use this medicine if you are allergic to chlorpheniramine or phenylephrine. (rexhealth.com)
  • It is not known whether chlorpheniramine and phenylephrine will harm an unborn baby. (rexhealth.com)
  • It is not known whether chlorpheniramine and phenylephrine passes into breast milk or if it could harm a nursing baby. (rexhealth.com)
  • How should I take chlorpheniramine and phenylephrine? (rexhealth.com)
  • Chlorpheniramine, phenylephrine, and pyrilamine can pass into breast milk and may cause side effects in the nursing baby. (unchealthcare.org)
  • Be the first to review Brompheniramine, Chlorpheniramine, Methscopolamine, Phenylephrine, And Pseudoephedrine(Oral) and share your experience with other Everyday Health users. (everydayhealth.com)
  • Do not use chlorpheniramine, dextromethorphan, and phenylephrine if you have used an MAO inhibitor in the past 14 days. (johnstonhealth.org)
  • ANTIFLU POWDER (Acetaminophen, L-Phenylephrine Hcl, Chlorpheniramine Maleate) Powder, For Solution [Bayer HealthCare LLC. (gacovinolake.com)
  • From exactly what I can tell, Hista - vent da game is simply buffered Chlorpheniramine, methscopolamine, and phenylephrine. (sovawinetrail.com)
  • There is no known interaction times between phenylephrine and Chlorpheniramine, methscopolamine, and phenylephrine hydrochloride in our records. (sovawinetrail.com)
  • What is the most important information I should know about chlorpheniramine, methscopolamine, and pseudoephedrine? (cigna.com)
  • Chlorpheniramine, methscopolamine, and pseudoephedrine may also be used for purposes not listed in this medication guide. (cigna.com)
  • What should I discuss with my healthcare provider before taking chlorpheniramine, methscopolamine, and pseudoephedrine? (cigna.com)
  • FDA pregnancy category C. It is not known whether chlorpheniramine, methscopolamine, and pseudoephedrine will harm an unborn baby. (cigna.com)
  • How should I take chlorpheniramine, methscopolamine, and pseudoephedrine? (cigna.com)
  • What should I avoid while taking chlorpheniramine, methscopolamine, and pseudoephedrine? (cigna.com)
  • Drinking alcohol can increase certain side effects of chlorpheniramine, methscopolamine, and pseudoephedrine. (cigna.com)
  • Never use chlorpheniramine, codeine, and pseudoephedrine in larger amounts, or for longer than prescribed. (adventisthealthcare.com)
  • Many combination medicines contain chlorpheniramine or pseudoephedrine. (uwhealth.org)
  • You should not use this medicine if you are allergic to chlorpheniramine, ibuprofen, or pseudoephedrine, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. (pardeehospital.org)
  • Chlorpheniramine, ibuprofen, and pseudoephedrine can pass into breast milk and may harm a nursing baby. (pardeehospital.org)
  • What are the possible side effects of chlorpheniramine, ibuprofen, and pseudoephedrine (Advil Allergy Sinus, Advil Childrens Allergy Sinus, Advil Multi-Symptom Cold)? (emedicinehealth.com)
  • The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza. (clinicaltrials.gov)
  • However, Sudal - 12, or Chlorpheniramine and pseudoephedrine, has been mainly linked to serious mental health complications when used assays in excess and heir for long periods of time. (ezinelocater.com)
  • Do not use it if you had an allergic reaction to hydrocodone, chlorpheniramine, or pseudoephedrine, or if you have severe lung or breathing problems, glaucoma, trouble passing urine, severe heart or blood vessel disease (including high blood pressure), or stomach or bowel blockage (including paralytic ileus). (baptistjax.com)
  • Some medicines can affect how hydrocodone/chlorpheniramine/pseudoephedrine works. (baptistjax.com)
  • Some over-the-counter medicines containing 4 milligrams of chlorpheniramine maleate include Coricidin HBP, Chlor-Trimeton, Aller-Chlor and Chlo-Amine, according to Drugs.com. (reference.com)
  • Comparative pharmacology of chlorpheniramine (Chlor-Trimeton) and its optical isomers. (semanticscholar.org)
  • Chlorpheniramine maleate is an antihistamine medication used as an active ingredient in many different non-prescription medicines (such as Chlor-Trimeton ® ) and prescription drugs. (emedtv.com)
  • Who should not take Chlorpheniramine-Acetaminophen Tablet? (webmd.com)
  • Chlorpheniramine comes as a tablet, a capsule, an extended-release (long-acting) tablet and capsule, a chewable tablet, and a liquid to take by mouth. (medlineplus.gov)
  • Chlorpheniramine comes in tablet, capsule, and liquid form. (emedtv.com)
  • Before you give a chlorpheniramine product to a child, check the package label to find out how much medication the child should receive. (medlineplus.gov)
  • Chlorpheniramine maleate is an antihistamine medication available widely over the counter, notes Drugs.com. (reference.com)
  • Chlorpheniramine maleate is one of the two most common forms of the medication (the other is chlorpheniramine tannate). (emedtv.com)
  • Chlorpheniramine maleate also blocks acetylcholine receptors, an action that produces some of the unpleasant side effects of the medication, such as dry mouth or difficulty urinating, but also helps to relieve a runny nose. (emedtv.com)
  • Ask your pharmacist or healthcare provider for more information if you aren't sure chlorpheniramine is the right medication for you. (emedtv.com)
  • In some drugs, Chlorpheniramine is combined with a cough suppressant called dextromethorphan. (vetinfo.com)
  • Taking chlorpheniramine with other drugs that make you sleepy or slow your breathing can worsen these effects. (everydayhealth.com)
  • Like all drugs, side effects are possible with chlorpheniramine. (emedtv.com)
  • Chlorpheniramine blocks the effects of histamine in the body. (vetdepot.com)
  • Chlorpheniramine works by blocking the effects of histamine, a substance released by cells in the body that produce allergy symptoms. (canada.com)
  • Combination of Chlorpheniramine and ibuprofen combination have long been postulated to treat common cold and its symptoms. (biovista.com)
  • Chlorpheniramine maleate is an active ingredient found in many prescription medications and over-the-counter products used for treating allergies, hives, and the common cold. (emedtv.com)
  • Chlorpheniramine is an active ingredient in many different products. (emedtv.com)
  • Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. (rexhealth.com)
  • tell your doctor and pharmacist if you are allergic to chlorpheniramine, any other medications, or any of the ingredients in the chlorpheniramine product you plan to use. (medlineplus.gov)
  • What is the most important information I should know about acetaminophen and chlorpheniramine? (rexhealth.com)
  • Acetaminophen and chlorpheniramine is a combination medicine used to treat headache, runny nose, sneezing, watery eyes, and pain or fever caused by allergies, the common cold, or the flu. (rexhealth.com)
  • Drug information on Excodin (10mg/4mg/75mg/1.5mg/5ml) (Codeine Phosphate 10mg + Chlorpheniramine Maleate 4mg + Sodium Citrate 75mg + Menthol 1.5mg/5ml) from Gujarat Terce Laboratories Ltd. (medindia.net)
  • Nonprescription cough and cold combination products, including products that contain chlorpheniramine, can cause serious side effects or death in young children. (medlineplus.gov)
  • Alcohol can make the side effects of chlorpheniramine worse. (medlineplus.gov)
  • In this study, no side effects were reported among 5 infants exposed to chlorpheniramine in breastmilk. (nih.gov)
  • Drinking alcohol can increase certain side effects of chlorpheniramine. (adventisthealthcare.com)
  • If you are over 65 years of age, you may be more likely to experience side effects from chlorpheniramine/dextromethorphan/phenylpropanolamine. (drugster.info)
  • Hydrocodone and chlorpheniramine combination is used to relieve cough and nasal congestion (stuffy nose) associated with the common cold or allergy in adults. (mayoclinic.org)
  • What Is Chlorpheniramine (Allergy)? (everydayhealth.com)
  • Abstract We compared the cardiac electrophysiological actions of two types of H 1 -receptor antagonists-the piperidines, astemizole and terfenadine, and the nonpiperidines, chlorpheniramine and pyrilamine-in vitro in guinea pig ventricular myocytes and in vivo in chloralose-anesthetized dogs. (ahajournals.org)
  • Chlorpheniramine and pyrilamine blocked I Kr relatively weakly (IC 50 =1.6 and 1.1 μmol/L, respectively) and I Ks and I K1 less than 20% at 10 μmol/L. Astemizole and terfenadine (1.0 to 3.0 mg/kg IV) significantly prolonged the QTc interval and ventricular effective refractory period in vivo. (ahajournals.org)
  • Chlorpheniramine and pyrilamine (≤3.0 mg/kg) did not significantly affect these parameters. (ahajournals.org)
  • The effects were compared with those of two standard, non-piperidine-containing H 1 -receptor antagonists, chlorpheniramine and pyrilamine. (ahajournals.org)
  • 1. The paper describes the mental disturbances of 44 abusive cases of "BRON," an over-the-counter (OTC) cough suppressant solution containing methylephedrine, codeine, caffeine, and chlorpheniramine. (amphetamines.com)
  • It contains the active ingredients paracetamol and chlorpheniramine maleate. (news-medical.net)
  • Paracetamol and chlorpheniramine maleate may affect your developing baby if you take it during pregnancy. (news-medical.net)
  • Paracetamol and chlorpheniramine maleate may pass into human breast milk. (news-medical.net)
  • You are hypersensitive to, or have had an allergic reaction to paracetamol, chlorpheniramine maleate, any other antihistamine or any other ingredients listed at the end of this leaflet. (news-medical.net)
  • I n the present study we analyzed the effect of continuous intraventricular infusion of the histamine H(1) receptor antagonist d-chlorpheniramine on the performance of 32-month-old Fischer 344/Brown Norway F1 hybrid rats in the place version of the Morris water maze and in two different tests of anxiety (open field and black-and-white exploration). (biopsychiatry.com)
  • Chlorpheniramine (CH), a histamine H 1 -receptor antagonist commonly prescribed in combination with CQ for the treatment of CQ-induced pruritus, has been shown to reverse CQ resistance in African isolates of P. falciparum malaria (Basco & Le Bras 1994, Okonkwo et al. (scielo.br)
  • This study examined concurrently the concentrations of chlorpheniramine and presence of H1‐receptor antagonist in plasma after administration of 8 mg chlorpheniramine in normal volunteers. (semanticscholar.org)
  • Extra- and intracellular formation of reactive oxygen species by human neutrophils in the presence of pheniramine, chlorpheniramine and brompheniramine. (nel.edu)
  • Jancinová I, Drábiková A, Nosál' A, Holománová A, Extra- and intracellular formation of reactive oxygen species by human neutrophils in the presence of pheniramine, chlorpheniramine and brompheniramine. (nel.edu)
  • Small (2 to 4 mg), occasional doses of chlorpheniramine are acceptable during breastfeeding. (nih.gov)
  • Can medicine with chlorpheniramine help inner ear problems? (drugs.com)
  • Before you start any new medicine, check the label to see if it has chlorpheniramine in it too. (drugs.com)
  • Ask your doctor before taking chlorpheniramine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. (everydayhealth.com)
  • ask your doctor about the safe use of alcohol while you are taking chlorpheniramine. (medlineplus.gov)
  • Hydrocodone/chlorpheniramine (Vituz). (nih.gov)