Incidence of bladder cancer in a cohort of workers exposed to 4-chloro-o-toluidine while synthesising chlordimeform. (1/7)

Between 1982 and 1990 seven cases of bladder cancer were detected in a group of 49 workers who were synthesising chlordimeform from 4-chloro-o-toluidine. Latency periods ranged from 15 to 23 years. The incidence of bladder tumours in this group was significantly higher than that of the cancer registers of the former GDR, Saarland, and Denmark by factors of 89.7, 53.8, and 35.0 respectively. This provides further evidence that monocyclic aromatic amines such as 4-chloro-o-toluidine may be carcinogenic in humans.  (+info)

Octopamine and experience-dependent modulation of aggression in crickets. (2/7)

Intraspecific aggression is influenced in numerous animal groups by the previous behavioral experiences of the competitors. The underlying mechanisms are, however, mostly obscure. We present evidence that a form of experience-dependent plasticity of aggression in crickets is mediated by octopamine, the invertebrate counterpart of noradrenaline. In a forced-fight paradigm, the experience of flying maximized the aggressiveness of crickets at their first encounter and accelerated the subsequent recovery of aggressiveness of the normally submissive losers, without enhancing general excitability as evaluated from the animals' startle responses to wind stimulation. This effect is transitory and concurrent with the activation of the octopaminergic system that accompanies flight. Hemocoel injections of the octopamine agonist chlordimeform (CDM) had similar effects on aggression but also enhanced startle responses. Serotonin depletion, achieved using alpha-methyl-tryptophan, enhanced startle responses without influencing aggression, indicating that the effect of CDM on aggression is not attributable to increased general excitation. Contrasting this, aggressiveness was depressed, and the effect of flying was essentially abolished, in crickets depleted of octopamine and dopamine using alpha-methyl-p-tyrosine (AMT). CDM restored aggressiveness in AMT-treated crickets, indicating that their depressed aggressiveness is attributable to octopamine depletion rather than to dopamine depletion or nonspecific defects. Finally, the flight effect was blocked in crickets treated with the octopamine receptor antagonist epinastine, or with the alpha-adrenoceptor and octopamine receptor antagonist phentolamine, but not with the beta-adrenoceptor antagonist propranolol. The idea that activity-specific induction of the octopaminergic system underlies other forms of experience-dependent plasticity of aggressive motivation in insects is discussed.  (+info)

Octopamine partially restores walking in hypokinetic cockroaches stung by the parasitoid wasp Ampulex compressa. (3/7)

When stung by the parasitoid wasp Ampulex compressa, cockroaches Periplaneta americana enter a hypokinetic state that is characterized by little, if any, spontaneous locomotor activity. In the present study we investigate the effect of an octopamine receptor agonist and an antagonist on the locomotor behavior of stung and control cockroaches. We show that in cockroaches stung by a wasp the octopamine receptor agonist chlordimeform induces a significant increase in spontaneous walking. In good agreement, in control individuals an octopamine receptor antagonist significantly reduces walking activity. Adipokinetic hormone I (AKH-I) promotes spontaneous walking in controls but does not do so in stung individuals, which suggests that the venom effect is most probably not mediated by AKH-I. Dopamine receptor agonists or antagonists had no significant effect on the spontaneous walking of stung or control cockroaches, respectively. The effect of the octopamine receptor agonist was maximal when injected into the brain, suggesting that the wasp venom interferes with octopaminergic modulation of walking initiation in central structures of the cockroach brain.  (+info)

The effect of octopaminergic compounds on the behaviour and transmission of Gyrodactylus. (4/7)

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The effects of phenelzine and other monoamine oxidase inhibitor antidepressants on brain and liver I2 imidazoline-preferring receptors. (5/7)

1. The binding of [3H]-idazoxan in the presence of 10(-6) M (-)-adrenaline was used to quantitate I2 imidazoline-preferring receptors in the rat brain and liver after chronic treatment with various irreversible and reversible monoamine oxidase (MAO) inhibitors. 2. Chronic treatment (7-14 days) with the irreversible MAO inhibitors, phenelzine (1-20 mg kg-1, i.p.), isocarboxazid (10 mg kg-1, i.p.), clorgyline (3 mg kg-1, i.p.) and tranylcypromine (10 mg kg-1, i.p.) markedly decreased (21-71%) the density of I2 imidazoline-preferring receptors in the rat brain and liver. In contrast, chronic treatment (7 days) with the reversible MAO-A inhibitors, moclobemide (1 and 10 mg kg-1, i.p.) or chlordimeform (10 mg kg-1, i.p.) or with the reversible MAO-B inhibitor Ro 16-6491 (1 and 10 mg kg-1, i.p.) did not alter the density of I2 imidazoline-preferring receptors in the rat brain and liver; except for the higher dose of Ro 16-6491 which only decreased the density of these putative receptors in the liver (38%). 3. In vitro, phenelzine, clorgyline, 3-phenylpropargylamine, tranylcypromine and chlordimeform displaced the binding of [3H]-idazoxan to brain and liver I2 imidazoline-preferring receptors from two distinct binding sites. Phenelzine, 3-phenylpropargylamine and tranylcypromine displayed moderate affinity (KiH = 0.3-6 microM) for brain and liver I2 imidazoline-preferring receptors; whereas chlordimeform displayed high affinity (KiH = 6 nM) for these receptors in the two tissues studied, Clorgyline displayed very high affinity for rat brain (KiH = 40 pM) but not for rat liver I2 imidazoline-preferring receptors (KiH = 169 nM). 4. Preincubation of cortical or liver membranes with phenelzine (10-4 M for 30 min) did not alter the total density of I2 imidazoline-preferring receptors, indicating that this irreversible MAO inhibitor does not irreversibly bind to I2 imidazoline-preferring receptors. In contrast, preincubation with 10-6 Mclorgyline reduced by 40% the Bmax of [3H]-idazoxan to brain and liver I2 imidazoline-preferring receptors.5. Chronic treatment (7 days) with the inducers of cytochrome P-450 enzymes phenobarbitone (40 or 80 mg kg-1, i.p.), 3-methylcholanthrene (20 mg kg-1, i.p.) or 2-methylimidazole (40 mg kg-1, i.p.) did not alter the binding parameters of [3H]-idazoxan to brain and liver 12 imidazoline-preferring receptors.The compound SKF 525A, a potent inhibitor of cytochrome P-450 enzymes which forms a tight but reversible complex with the haemoprotein, completely displaced with moderate affinity (KiH = 2-10 microM)the specific binding of [3H]-idazoxan to brain and liver 12 imidazoline-preferring receptors. Preincubation of total liver homogenates with 3 x 10-4 M phenelzine in the presence of 10-3 M NADH, a treatment that irreversibly inactivates the haeme group of cytochrome P-450, did not reduce the density of liver I2 imidazoline-preferring receptors. These results discounted a possible interaction of [3H]-idazoxan with the haeme group of cytochrome P-450 enzymes.6. Together the results indicate that the down-regulation of I2 imidazoline-preferring receptors is associated with an irreversible inactivation of MAO (at least in the brain) that is not related either to the affinity of the MAO inhibitors for I2 imidazoline-preferring receptors or to an irreversible binding to these putative receptors. These findings indicate a novel effect of irreversible MAO inhibitors in the brain and suggest a new target for these compounds that could be of relevance in the treatment of depression, a disease in which an increased density of brain I2 imidazoline-preferring receptors has been reported.  (+info)

Chemistry, biological activity, and uses of formamidine pesticides. (6/7)

The formamidines, a relatively new group of acaricide-insecticides, are novel both in their range of biological activities and in their mode of action, which is presently unknown. This paper is a review of the historical development, properties, structures, uses, and chemistry of this group of pesticides, with particular emphasis on chlordimeform (Galecron or Fundal), N'-4-chloro-o-tolyl-N,N-dimethylformamidine, and amitraz, 1,3=di-(2,4-dimethylphenylimino)-2-methyl-2-azapropane. Their biological activity and uses are defined by their toxicity to spider mites, ticks, and certain insects, and they are particularly effective against juvenile and resistant forms of these organisms. A significant, but poorly understood feature of their field effectiveness is their breadth of toxic action which includes direct lethality, excitant-repellant behavioral effects, and chemosterilization. They are generally of low hazard for nontarget species with the significant exception of predaceous mites. Several aspects of the chemistry of these compounds are considered, including structure--activity relations, synthetic pathways, isomerism and configuration, and their chemical and environmental stability. A significant feature of the metabolism and toxicity of these agents is the possible activation of chlordimeform by N-demethylation in vivo. Strong evidence for this has been presented with the cattle tick, but recent results discussed here suggest that in other species, i.e., mice, German cockroaches or black cutworm eggs, N-demethylation is neither a strong activation nor a detoxication reaction.  (+info)

Biochemical and physiological effects of chlordimeform. (7/7)

Chlordimeform is a relatively new acaricide/insecticide, whose mode of action we have investigated. It appears to interfere with amine-mediated control of nervous and endocrine systems in a variety of ways. Specifically, chlordimeform causes a build-up of the amines 5-hydroxytryptamine and to a lesser extent norepinephrine in the rat brain in vivo, antagonizes the in vivo action of reserpine in the rat (reserpine depletes amine stores in the CNS), inhibits monoamine oxidase from rat liver in vitro, and causes hypotension in rabbits. In the American cockroach it directly stimulates the heart in situ, acts synergistically with tryptamine in vivo, inhibits amine-N-acetyltransferase from cockroach head in vitro, causes accumulation of indolamines in cockroaches in vivo, and blocks the stimulation of adenylate cyclase by octopamine in the cockroach CNS in situ. It also inhibits tryptamine metabolism in whole mites in vitro.  (+info)

No published study on the carcinogenicity of chlordimeform was available.. para-Chloro-ortho-toluidine, a metabolite of chlordimeform, was tested for carcinogenicity in two strains of mice and two strains of rats by oral administration in the diet. It was carcinogenic in both strains of mice, producing haemangiosarcomas. The studies in rats were not indicative of a carcinogenic effect, but certain limitations in their design were noted.. Chlordimeform is metabolized to a number of compounds, including para-chloro-ortho-toluidine, which has been identified in the urine of several animal species and of humans.. The available data were inadequate to evaluate the teratogenicity of chlordimeform to experimental animals.. Chlordimeform was negative in tests for DNA damage or mutagenicity in several cellular systems. No data were available, however, with regard to its mutagenicity in mammals, and no overall evaluation of the mutagenicity of chlordimeform could be made. ...
chlordimeform definition: Noun (uncountable) 1. An acaricide active mainly against the motile forms of mites and ticks and against eggs and early instars of some Lepidoptera insects; it is no longer widely used....
Chlordimeform (N(4-chloro-o-tolyl)-N, N-dimethylformamidine; CDM) is a formamidine insecticide/acaricide whose major active metabolite is its N-monomethyl analog, desmethylchlordimeform, (DCDM). While their pesticidal action in invertebrates appears to be related to activation of octopamine receptors, their mechanism of action in mammals has not been established. Because of similarities between octopamine and adrenergic receptors and suggestions of CDM and DCDM action on adrenoceptors, the in vitro interactions of CDM and DCDM with adrenoceptors were studied. In mouse brain membrane preparations CDM inhibited the binding of [3H]-clonidine to alpha2- adrenoceptors and of [3H]-WB4101 to alpha1-adrenoceptors with IC50 values of 18.2 and 87 μM, respectively. DCDM was a much more potent inhibitor, with IC50 values toward alpha2−, and alpha1-adrenoceptors of 44 nM and 1 μM, respectively. Both compounds were only weak inhibitors of the binding of [3H]-dihydroalprenolol to beta-adrenoceptors and of [3H]
The DoD has nukes, nerve gas, anthrax, agent orange, napalm, etc., and people are worried that they can remote control beetles?. If you want to be a hippy, fine, but there is no need to be patently irrational about it.. As for the sentiment that this is cruel, I dont think the beetle minds, seeing as its nervous system is not complex enough to permit any sort of thought beyond direct physical response to stimuli.. For comparison, the wasp Ampulex Compressa stings a cockroach so as to briefly paralyze it, then again so as disable the escape reflex, and then steers the roach to its nest where it lays eggs on, which hatch, penetrate the roach, and devour it alive as the larvae gestate. That seems a much crueler fate for the beetle, but I dont see anyone launching an extermination campaign against Ampulex Compressa. Of course, maybe that is that is because Ampulex Compressa is not a convenient political target.. ...
2,4,5-T, aldrin, binapacryl, captafol, chlordane, chlordimeform, chlorobenzilate, DDT, DNOC and its salts, ethylene dichloride, ethylene oxide 1,2-dibromoethane (EDB), dieldrin, dinoseb, fluoroacetamide, HCH, heptachlor, hexachlorobenzene, lindane, mercury compounds, monocrotophos, parathion, pentachlorophenol, toxaphene and tributyl tin, plus certain formulations of methamidophos, methyl-parathion, and phosphamidon, as well as dustable-powder formulations containing a combination of benomyl at or above 7 percent, carbofuran at or above 10 percent and thiram at or above 15 percent that are listed as severely hazardous pesticide formulations ...
We used COX-2-deficient mice to investigate the role of COX-2 in the mechanisms of liver I/R injury. Our data demonstrate that COX-2−/− mice, compared with their WT counterparts, were significantly less susceptible to liver I/R reperfusion injury. COX-2−/− mice showed reduced sGPT and sGOT levels after I/R injury, which indicate that liver damage was reduced in these mice as compared with WT controls. Inflammatory processes are mediated by multiple molecular mechanisms, and COX-2 is a major inflammatory mediator (44). Our observation that the lack of COX-2 confers a protective role in liver I/R injury is supported by our own celecoxib studies, in which selective COX-2 inhibition ameliorated mouse liver I/R injury. This observation is also supported by other publications, in which COX-2 inhibition was beneficial in rat liver I/R injury (22, 23).. Bcl-2 and Bcl-xL play an important role in inhibition of apoptotic cell death and are essential for maintenance of major organ systems (49). ...
In a well-documented example of external parasite control, an emerald cockroach wasp (Ampulex compressa) enslaves a much larger cockroach (Periplaneta americana). The wasp injects a neurotoxin into the cockroachs brain. This toxin kills off the roachs ability to control its own movement but doesnt paralyze it entirely. The wasp is then able to grasp the roachs antenna and lead it into a nest before laying an egg in the live cockroachs body ...
Some neurons in Aplysia have receptors which are much more sensitive to octopamine than any other structurally related compound. Most such receptors mediate a hyperpolarizing conductance increase to K(+). These responses when considered with the octopamine content of whole ganglia and single neurons strongly suggest that octopamine is a neurotransmitter in Aplysia.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition may worsen ...
Upon pathogen infection, the nervous system regulates innate immunity to confer coordinated protection to the host. However, the precise mechanisms of such regulation remain unclear. Previous studies have demonstrated that OCTR-1, a putative G protein-coupled receptor for catecholamine, functions in the sensory neurons designated "ASH" to suppress innate immune responses in Caenorhabditis elegans. It is unknown what molecules act as OCTR-1 ligands in the neural immune regulatory circuit. Here we identify neurotransmitter octopamine (OA) as an endogenous ligand for OCTR-1 in immune regulation and show that the OA-producing RIC neurons function in the OCTR-1 neural circuit to suppress innate immunity. RIC neurons are deactivated in the presence of pathogens but transiently activated by nonpathogenic bacteria. Our data support a model whereby an octopaminergic immunoinhibitory pathway is tonically active under normal conditions to maintain immunological homeostasis or suppress unwanted innate ...
Nardil tablets contain the active ingredient phenelzine, which is a type of antidepressant known as a monoamine oxidase inihibitor (MAOI).
Phenelzine may interact with many different medicines, including other antidepressants and medications to help decrease blood pressure. A major concer
I am sorry, this may be a little long. I have a fatty liver - I am overweight predominantly due to eating and drinking too much and not shifting my bum as much as I should. I am in my mid 50s and have a bad back and a bad hip which means I can no longer get around as much due to the pain - I know the first thing my GP will say is lose weight, so it is a vicious circle. I used to be lovely and slim and only have myself to blame. My BMI is high 30s. I start a diet - I am their greatest
The biogenic amine octopamine plays a critical role in the regulation of many physiological processes in insects. Octopamine transmits its action through a set of specific G-protein coupled receptors (GPCRs), namely octopamine receptors. Here, we report on a β-adrenergic-like octopamine receptor gene (BdOctβR1) from the oriental fruit fly, Bactrocera dorsalis (Hendel), a destructive agricultural pest that occurs in North America and the Asia-Pacific region. As indicated by RT-qPCR, BdOctβR1 was highly expressed in the central nervous system (CNS) and Malpighian tubules (MT) in the adult flies, suggesting it may undertake important roles in neural signaling in the CNS as well as physiological functions in the MT of this fly. Furthermore, its ligand specificities were tested in a heterologous expression system where BdOctβR1 was expressed in HEK-293 cells. Based on cyclic AMP response assays, we found that BdOctβR1 could be activated by octopamine in a concentration-dependent manner, confirming that
Phenelzine is a monoamine oxidase inhibitor (MAOI) that works by increasing the levels of certain chemicals in the brain. Phenelzine is used to treat symptoms of depression that may include feelings of sadness, fear, anxiety, or worry about physical health (hypochondria). This medication is usually given after other...
Here are 14 realistic (non-diet) methods to detox your liver I have described in their Top 14 Foods That Cleanse the Liver. if you follow this you will get success
The role of cyclic AMP in the octopaminergic modulation of the dorsal longitudinal flight muscles of the locust Schistocerca gregaria has been investigated. Several techniques have been used to elevate cyclic AMP levels in this tissue by mechanisms that bypass the receptor activation stage. These include the use of phosphodiesterase inhibitors to block the metabolism of cyclic nucleotides, the use of forskolin, the diterpene activator of adenylate cyclase, and the direct application of permeable and phosphodiesterase-resistant analogues of cyclic AMP. All these approaches can be shown to mimic the modulatory effects of octopamine on the flight muscle. Surprisingly, the phosphodiesterase inhibitors used were not able to potentiate the actions of octopamine on this preparation. Octopamine increases cyclic AMP levels in a similar fashion in all five motor units of this muscle, an effect that is selectively blocked by phentolamine, an α-adrenergic blocking agent that blocks octopamine receptors in ...
Phenelzine (Nardil, Nardelzine) is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is used as an antidepressant and anxiolytic. Along with tranylcypromine and isocarboxazid, phenelzine is one of the few non-selective and irreversible MAOIs still in widespread clinical use. It is typically available in 15 mg tablets and doses usually range from 30-90 mg per day, with 15 mg every day or every other day suggested as a maintenance dose following a successful course of treatment. Phenelzine is used primarily in the treatment of major depressive disorder (MDD). Patients with depressive symptomology characterized as "atypical", "nonendogenous", and/or "neurotic" respond particularly well to phenelzine. The medication is also useful in patients who do not respond favorably to first and second-line treatments for depression, or are "treatment-resistant". In addition to being a recognized treatment for major depressive disorder, phenelzine is effective in ...
order Pregabalin online uk The next revolutionary gaming app? Maybe someday. But to the emerald wasp, this grisly battle is a routine part of its everyday life.. For decades, scientists have tried to understand the complex and gruesome relationship between the parasitic emerald wasp (Ampulex compressa) and its much larger victim, the common household cockroach (Periplaneta americana).. At first glance, this parasite-prey relationship seems much like any other: the female wasp stings the cockroach, lays an egg on its abdomen, and once hatched, the hungry larva feeds on the cockroach. However, while most parasitic insects tend to paralyse their victims with a venomous sting, the emerald wasp instead does something a lot more interesting - it manipulates the cockroachs behavior, essentially transforming it into a zombie slave.. With two stings the cockroach is left with the ability to walk, but is entirely robbed of the power to initiate its own movement. The wasp, now tired after administering ...
The biogenic amine octopamine is a neuromodulatory transmitter in insects that plays an important role in a variety of behavioral contexts (e.g. Mentel et al, 2003). We address the functional role of octopaminergic neurons (ONs) in the locust motor system combining experimental and modeling approaches. A well described network of motor neurons reliably generates rhythmic locomotory patterns and a parallel small-sized network of ONs connects to this motor network, the connectivity of which has been described in detail (Field et al., 2008). Amongst the latter, octopaminergic unpaired median neurons, with either dorsal or ventral cell bodies (DUM or VUM neurons, respectively) are clustered along the midline of the thoracic and abdominal ganglia. Both networks receive top-down input from central areas of the suboesophageal ganglion and the brain, and are activated in parallel with high synchrony (Burrows & Pflüger, 1995; Duch & Pflüger, 1999). Previous results (Bräunig & Pflüger, 2001) suggest ...
The biogenic amine octopamine is a neuromodulatory transmitter in insects that plays an important role in a variety of behavioral contexts (e.g. Mentel et al, 2003). We address the functional role of octopaminergic neurons (ONs) in the locust motor system combining experimental and modeling approaches. A well described network of motor neurons reliably generates rhythmic locomotory patterns and a parallel small-sized network of ONs connects to this motor network, the connectivity of which has been described in detail (Field et al., 2008). Amongst the latter, octopaminergic unpaired median neurons, with either dorsal or ventral cell bodies (DUM or VUM neurons, respectively) are clustered along the midline of the thoracic and abdominal ganglia. Both networks receive top-down input from central areas of the suboesophageal ganglion and the brain, and are activated in parallel with high synchrony (Burrows & Pflüger, 1995; Duch & Pflüger, 1999). Previous results (Bräunig & Pflüger, 2001) suggest ...
2016 Phenelzine (CAS 51-71-8) Industry Market Report is a market research report available at US $2800 for a Single User PDF License from RnR Market Research Reports Library.
Porosomes are the universal secretory machinery in cells, where membrane-bound secretory vesicles transiently dock and fuse to release intravesicular contents to the outside of the cell during cell secretion. Studies using atomic force microscopy, el
but they also sent me down stairs via the wheel chair to have an ultrasound on I thought my liver - I still dont know if she took that for sure, she kept trying to take my gal bladders picture - I know a couple of years ago it a one small stones, but was told not to worry, I know she was doing her job but my tummy area had about all the fun for one day I could take ...
... (Nardil, Nardelzine) is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is used as an antidepressant and anxiolytic. Along with tranylcypromine and isocarboxazid, phenelzine is one of the few non-selective and irreversible MAOIs still in widespread clinical use. It is typically available in 15 mg tablets and doses usually range from 30-90 mg per day, with 15 mg every day or every other day suggested as a maintenance dose following a successful course of treatment. Phenelzine is used primarily in the treatment of major depressive disorder (MDD). Patients with depressive symptomology characterized as "atypical", "nonendogenous", and/or "neurotic" respond particularly well to phenelzine. The medication is also useful in patients who do not respond favorably to first and second-line treatments for depression, or are "treatment-resistant". In addition to being a recognized treatment for major depressive disorder, phenelzine is effective in ...
The Ames test is a widely employed method that uses bacteria to test whether a given chemical can cause mutations in the DNA of the test organism. More formally, it is a biological assay to assess the mutagenic potential of chemical compounds. A positive test indicates that the chemical is mutagenic and therefore may act as a carcinogen, because cancer is often linked to mutation. The test serves as a quick and convenient assay to estimate the carcinogenic potential of a compound because standard carcinogen assays on mice and rats are time-consuming (taking two to three years to complete) and expensive. However, false-positives and false-negatives are known. The procedure was described in a series of papers in the early 1970s by Bruce Ames and his group at the University of California, Berkeley. The Ames test uses several strains of the bacterium Salmonella typhimurium that carry mutations in genes involved in histidine synthesis. These strains are auxotrophic mutants, i.e. they require ...
... s are the agents that interfere with the mutagenicity of a substance. The interference can be in the form of prevention of the transformation of a mutagenic compound into mutagen[clarification needed], inactivation, or otherwise the prevention of Mutagen-DNA reaction. Antimutagens can be classified into: Desmutagens, that inactivate the chemical interactions before the mutagen attacks the genes and Bio-antimutagens, that stop the mutation process once after the genes are damaged by mutagens. There are a number of naturally occurring anti-mutagens that show their efficient action. Nutrients such as vitamins and minerals are examples of micronutrients that are necessary for the proper maintenance of metabolism homeostasis in humans and other species. Micronutrients are also pointed to perform a role in genome stability acting as potential antimutagenic agents (see the examples below): Carotenoids: Induction of single break DNA repair by a rejoining mechanism and elimination of ...
Members of this genus are often used in studies investigating the metabolism of drugs, because these species metabolize a wide range of drugs in manners similar to mammalian enzyme systems.[5] Many species are also capable of oxidizing polycyclic aromatic hydrocarbons, a class of stable organic molecules that tends to persist in the environment and contains many known carcinogenic and mutagenic compounds.[6]. The presence of a cytochrome P-450 has been demonstrated in C. bainieri.[7]. ...
Chlorphenamidine * Ciba 8514 * Ciba - C85l4 * N,N-Dimethyl-N-(2-methyl-4-chlorophenyl)formamidine * ENT 27335 * ENT 27567 * EP ...
Fenitrothion, trichlorfon, and chlorphenamidine. Alphamethrin. Bacillus thuringiensis kurstaki. Tebufenozide. 1972. 10,000. 0. ...
Report of Schering AG, Dr Ko/So, 17.10.67 Schering AG (1967a) Ruckstandsuntersuchungen chlorphenamidine III Mitteilung 1967. ...
... chlorphenamidine, and alphamethrin) were included; surfaces sprayed with lepidopteron-specific insecticide (i.e., tebufenozide ...
Chlorphenamidine. General subdivision. toxicity. --. adverse effects.. 650 02 - SUBJECT ADDED ENTRY--TOPICAL TERM. ...
Chlorphenamidine ; Ovulation ; Toxicity ; Pesticides ; LH ; Oocytes ; Hamsters ; Dose-response relationships ; Biological ...
Chlorphenamidine--toxicity--adverse effects.. Environmental exposure.. Occupational exposure. National Library of Medicine Call ...
Chlorphenamidine--adverse effects ; Chlrophenamidine--toxicity ; Environmental Exposure ; Occupational Exposure ; Environmental ...
16) Chlordimeform ( Chlorphenamidine 살충제) : CASRN 19044-88-3. 17) Clofentezine ( 살충제 ) : CASRN 74115-24-5 ...
Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. Amidines include carboxamidines, sulfinamidines and phosphinamidines ...
Chlorphenamidine. Guanidines. Stilbamidines. Search for this term in our Faculty Database. View this term at the NCBI website ...
Animals , Receptors, Histamine/physiology , Eating , Chickens , Piperidines , Chlorphenamidine , Famotidine 15. A Case of ...
Chlorphenamidine/therapeutic use , Central Nervous System Diseases/diagnosis , Central Nervous System Diseases/drug therapy , ...
in-tray none chlorphenamidine none☆☼. *Rongmohl tower 34 New City 2154, Bali road MPB. ...
chI, Ch D, Ch B, CH, Online Electronic Medical Dictionary Terminology, Articles, Glossary
chlorotriazine dyes chlorous chlorous acid chlorozotocin chlorphenamidine chlorphenesin chlorphenindione chlorpheniramine (0) ...

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