Encyclopedias as Topic
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
Drug Information Services
Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
Formularies as Topic
Works about lists of drugs or collections of recipes, formulas, and prescriptions for the compounding of medicinal preparations. Formularies differ from PHARMACOPOEIAS in that they are less complete, lacking full descriptions of the drugs, their formulations, analytic composition, chemical properties, etc. In hospitals, formularies list all drugs commonly stocked in the hospital pharmacy.
Medical Records Systems, Computerized
United States Food and Drug Administration
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
Selective Estrogen Receptor Modulators
A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
Estrogen Receptor alpha
Contraceptive Agents, Male
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
Biological Science Disciplines
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.
An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
Cytochrome P-450 Enzyme System
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism.
Cytochrome P-450 CYP2B1
A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.
Large-scale prediction and testing of drug activity on side-effect targets. (1/3)(+info)
Inactivation of the uterine estrogen receptor binding of estradiol during P-450 catalyzed metabolism of chlorotrianisene (TACE). Speculation that TACE antiestrogenic activity involves covalent binding to the estrogen receptor. (2/3)Chlorotrianisene (TACE) exhibits in vitro little or no binding to the uterine estrogen receptor (ER) but demonstrates potent estrogenic activity in vivo, indicating that TACE is a proestrogen/proantiestrogen. Our earlier studies demonstrated that the incubation of TACE with rat liver microsomes and NADPH generates a reactive intermediate (T*) which binds covalently to proteins. The current study examined the possibility that T* may inactivate the uterine ER. The incubation of TACE with rat liver microsomes and NADPH in the presence of rat uteri, under conditions which generate T*, markedly decreased the binding capacity of the ER for [3H]estradiol (E2). The evidence indicates that ER inactivation was probably due to irreversible (covalent) binding of T* to the E2 binding site. The possibility that the antiestrogenic action of TACE and of other triphenylethylenes involves such a novel mechanism is discussed. (+info)
Effect of oestrogen on liver function of prostatic cancer patients. (3/3)Liver function of patients with cancer of the prostate gland was studied while they were receiving oestrogen therapy. When synthetic oestrogens were given, raised values of serum aspartate and alanine amino-transferase (S.G.O.T. and S.G.P.T.) were found in about 30-50% of them. As treatment continued the increased values usually returned to normal levels. No serious liver damage was observed, though the serum bilirubin content rose temporarily in some patients. (+info)
Estrobin - Wikipedia
Estrobin, also known as α,α-di(p-ethoxyphenyl)-β-phenylbromoethylene and commonly abbreviated as DBE, is a synthetic, nonsteroidal estrogen of the triphenylethylene group that was never marketed. Chlorotrianisene, and subsequently clomifene and tamoxifen, were derived from it. Estrobin, similarly to other triphenylethylenes, is very lipophilic and hence very long-lasting in its duration of action. Similarly to chlorotrianisene, estrobin behaves a prodrug to a much more potent estrogen in the body. ...
List of estrogens available in the United States - Wikipedia
This is a complete list of estrogens and formulations that are approved by the FDA and available in the United States. Estrogens are used as hormonal contraceptives, in hormone replacement therapy, and in the treatment of gynecological disorders. Conjugated estrogens (Premarin) - 0.3 mg, 0.45 mg, 0.625 mg, 0.9 mg, 1.25 mg, 2.5 mg Esterified estrogens (Amnestrogen, Estratab, Evex, Femogen, Menest) - 0.3 mg, 0.625 mg, 1.25 mg, 2.5 mg Estradiol (Estradiol, Gynodiol, Innofem) - 0.5 mg, 1 mg, 2 mg Estradiol acetate (Femtrace) - 0.45 mg, 0.9 mg, 1.8 mg Estropipate (Estropipate, Ogen .625, Ogen 1.25, Ogen 2.5, Ogen 5, Ortho-Est) - 0.75 mg, 1.5 mg, 3 mg, 6 mg Synthetic conjugated estrogens (Cenestin, Enjuvia) - 0.3 mg, 0.45 mg, 0.625 mg, 0.9 mg, 1.25 mg Atypical (nitrogen mustard alkylating antineoplastic): Estramustine phosphate sodium (Emcyt) - 140 mg Discontinued: Chlorotrianisene (TACE) Dienestrol (Synestrol) Diethylstilbestrol (DES, Diethylstilbestrol, Stilbestrol, Stilbetin) Ethinylestradiol ...
Prostate Cancer | Centru Oncologie Severin
b) In patients who did not receive Flutamide, add it.. c) Prednisone 40mg / day p.o. may relieve pain.. e) Ketokenazol is administered in doses of 200mg x 3 / day. It is associated with nausea, vomiting, liver injury.. f) Abiraterone acetate 1000 mg / daily and prednisone 10 mg / day. Abiraterone acetate is an androgen synthesis inhibitor autocrine and / or paracrine through inhibition of cytochrome P 450. It is used in patients with recurrent prostate cancer after docetaxel treatment ineffective.. F). diethylstilbestrol or some other estrogen (Chlorotrianisene). The funds available are orchiectomy, LHRH agonists (luteinizing hormone releasing hormone) and androgens.. Androgen deprivation therapy (TDA) for localized disease. Overview. Previous neoadjuvant ADT radical prostatectomy is not recommended.. TDA concomitantly administered before or after radiotherapy prolongs survival in selected patients treated with radiotherapy.. All studies of neoadjuvant ADT short term (4-6 months) or long term ...
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Dr.Malpanis Blog: What is the best way to communicate with the referring doctor?
I prefer an alternate way of explaining things to the referring doctor , by keeping the patient in the loop. I document the entire discussion that I have with the patient, and send the complete consultation note to the general practitioner with the patient. This method has many benefits. The referring doctor understands my plan of action regarding the patients infertility. He has full information about the IVF procedure and what I am planning to do . More importantly, he can also check the patients understanding, so he can ensure she has realistic expectations of my treatment. This helps me to audit my consultation, and ensures that I have done a good job with clearing the patients doubts. At the same time the patient becomes the central part of the discussion. She is not left out from any information transfer. The referring doctor also gains confidence in the treatment offered at Malpani Infertility clinic. Since all the parties involved receive the same level of information , there is no ...
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A series of indanyl derivatives of diethylstilbestrol (DES) have recently been identified as inv vivo metabolites of DES. These compounds are of interest because they possess effective uterine estrogen receptor-binding affinity but poor biological activity. The X-ray crystal structures of three of these derivatives were determined and their conformations were compared with those of estradiol and DES. The more active derivatives, indenestrol A (I) and indenestrol B (II) have nearly identical conformations, in which the overall molecule is highly planar, the phenyl ring is twisted out of the plane of the indene rings by approximately 30 degrees, and the distance between the hydroxyl groups is 11.6 A. In the least active derivative, idanestrol (III), the methyl, ethyl, and phenyl substituents were found to be in the same side of the indane ring so that the molecule is constrained to an L-shape. The crystallographically observed conformations of I, II, III, DES, and estradiol, their competative ...
Chlorotrianisene. 12-24 mg/day Quadrosilan. 900 mg/day Estramustine phosphate. 140-1400 mg/day ...
Broparestrol Chlorotrianisene Estrobin Tadros W (1947). "Synthetic oestrogens related to triphenylethylene". Proceedings of the ...
Chlorotrianisene M2613 Triphenyliodoethylene Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an ...
Marion Merrell Dow
Scientists at Merrell had previously synthesized chlorotrianisene and ethamoxytriphetol. One of Richardson-Merrell's best-known ...
Allenolic acid Diethylstilbestrol Stilbestrol Chlorotrianisene Triphenylethylene R.A. Hill; H.L.J. Makin; D.N. Kirk; G.M. ...
Similarly to chlorotrianisene, estrobin behaves a prodrug to a much more potent estrogen in the body. Broparestrol ... Chlorotrianisene, and subsequently clomifene and tamoxifen, were derived from it. Estrobin, similarly to other ... 23-. ISBN 978-0-299-10480-1. Welsh AL (April 1954). "Use of synthetic estrogenic substance chlorotrianisene (TACE) in treatment ...
Welsh AL (April 1954). "Use of synthetic estrogenic substance chlorotrianisene (TACE) in treatment of acne". AMA Arch Derm ... Chlorotrianisene, methallenestril, and doisynoestrol are nonsteroidal estrogens structurally distinct from the stilbestrols ...
Ruenitz PC, Toledo MM (August 1981). "Chemical and biochemical characteristics of O-demethylation of chlorotrianisene in the ... is a nonsteroidal estrogen which is thought to be the major active metabolite of chlorotrianisene (CTA; TACE). It is a 1:1 ...
Chlorotrianisene. Synthetic. Nonsteroidal. ?. ,100 mg. ?. ?. ,48 mg. ? Methallenestril. Synthetic. Nonsteroidal. ?. 400 mg. ?. ...
It includes the estrogens chlorotrianisene, desmethylchlorotrianisene, estrobin (DBE), M2613, triphenylbromoethylene, ...
... a similar structure to stilbestrol derivatives like diethylstilbestrol and triphenylethylene derivatives like chlorotrianisene ...
... family and was structurally derived from diethylstilbestrol-like estrogens and antiestrogens such as chlorotrianisene and ...
... is a triphenylethanol and was derived from chlorotrianisene (TACE), a nonsteroidal triphenylethylene estrogen, and ...
... chlorotrianisene, broparestrol, ethamoxytriphetol, clomifene, tamoxifen, and more recently developed derivatives is also very ...
List of drugs: Cf-Ch
... chlorotrianisene (INN) chloroxylenol (INN) Chlorphed chlorphenamine (INN) chlorphenesin (INN) chlorphenoctium amsonate (INN) ...
... which itself was derived from the estrogen chlorotrianisene (also known as TACE)), was originally being studied in animals at ...
... chlorotrianisene, desmethylchlorotrianisene, estrobin (DBE), M2613, triphenylbromoethylene, triphenylchloroethylene, ...
Chlorotrianisene, or tri-p-anisylchloroethylene (TACE), is a potent marketed estrogen and a derivative of ...
... an enzyme Chlorotrianisene, a synthetic estrogen Tamil All Character Encoding - TACE-16 This disambiguation page lists articles ...
... chlorotrianisene Selective estrogen receptor modulators (ER mixed agonists/antagonists) Examples: tamoxifen, clomifene, ...
... chlorotrianisene, clomifene, clomifenoxide, cyclofenil, droloxifene, enclomifene, endoxifen, ethamoxytriphetol, fispemifene, ...
ATC code G03
G03BB01 Mesterolone G03BB02 Androstanolone G03CA01 Ethinylestradiol G03CA03 Estradiol G03CA04 Estriol G03CA06 Chlorotrianisene ...
List of combined sex-hormonal preparations
Chlorotrianisene/methyltestosterone (Tace mit Androgen) Conjugated estrogens/methyltestosterone (Premarin with ...
Selective estrogen receptor modulator
An example of a SERM with high IA and thus mostly estrogenic effects is chlorotrianisene, while an example of a SERM with low ...
List of estrogens available in the United States
Chlorotrianisene (TACE) Dienestrol (Synestrol) Diethylstilbestrol (DES, Diethylstilbestrol, Stilbestrol, Stilbetin) ...
... is the generic name of the drug and its INN, USAN, and BAN. It is also known as tri-p-anisylchloroethylene ( ... Chlorotrianisene (CTA), also known as tri-p-anisylchloroethylene (TACE) and sold under the brand name Tace among others, is a ... As an example, chlorotrianisene produces gynecomastia in men, albeit reportedly to a lesser extent than other estrogens, while ... Chlorotrianisene, also known as tri-p-anisylchloroethylene (TACE) or as tris(p-methoxyphenyl)chloroethylene, is a synthetic ...
Notes: Values are mean ± SD or range. ER RBA = Relative binding affinity to estrogen receptors of rat uterine cytosol. Uterine weight = Percentage change in uterine wet weight of ovariectomized rats after 72 hours with continuous administration of 1 μg/hour via subcutaneously implanted osmotic pumps. LH levels = Luteinizing hormone levels relative to baseline of ovariectomized rats after 24 to 72 hours of continuous administration via subcutaneous implant. Footnotes: a = Synthetic (i.e., not endogenous). b = Atypical uterotrophic effect which plateaus within 48 hours (estradiol's uterotrophy continues linearly up to 72 hours). Sources: See template ...
Chlorotrianisene. *Dienestrol *Dienestrol diacetate. *Diethylstilbestrol (stilbestrol). *Diethylstilbestrol esters/ethers * ...
Rubio-Póo C, Mandoki JJ, Mendoza-Patiño N, Lemini C, de la Peña A, Cruz F, Zavala E, Silva G, Garcia-Mondragón J, Fernández JM (1985). "The anticoagulant effect of prolame, N-(3-hydroxy-1,3,5(10)estratrien-17 beta-yl)-3-hydroxypropylamine, a novel amino-estrogen". Steroids. 45 (2): 159-70. PMID 3841425 ...
Other names: Ethylene, chlorotris(p-methoxyphenyl)-; Anisene; Chlorotrianisine; Chlorotris(p-methoxyphenyl)ethylene; Chlortrianizen; Clorestrolo; Clorotrisin; Hormonisene; Khlortrianizen; Merbentul; Metace; NSC-10108; Rianil; Tace; Tri-p-anisylchloroethylene; Tris(p-methoxyphenyl)chloroethylene; Chloortrianisestrol; Chlortrianisestrol; Chlorestrolo; 1,1,1-(1-Chloro-1-ethenyl-2-ylidene)-tris(4-methoxybenzene); Chlorotrianizen; Chlorotrisin; Chlortrianisen; CTA; Tace-fn; Trianisestrol; Benzene, 1,1,1-(1-chloro-1-ethenyl-2-ylidene)tris(4-methoxy)-; Tace (pharmaceutical ...
Chlorotrianisene - Wikipedia
Chlorotrianisene is the generic name of the drug and its INN, USAN, and BAN. It is also known as tri-p-anisylchloroethylene ( ... Chlorotrianisene (CTA), also known as tri-p-anisylchloroethylene (TACE) and sold under the brand name Tace among others, is a ... As an example, chlorotrianisene produces gynecomastia in men, albeit reportedly to a lesser extent than other estrogens, while ... Chlorotrianisene, also known as tri-p-anisylchloroethylene (TACE) or as tris(p-methoxyphenyl)chloroethylene, is a synthetic ...
Chlorotrianisene | ≥99%(HPLC) | Selleck | Estrogen/progestogen Receptor modulator ...
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Human Metabolome Database: Showing metabocard for Chlorotrianisene (HMDB0014414)
Chlorotrianisene. Description. Chlorotrianisene is only found in individuals that have used or taken this drug. It is a ... Showing metabocard for Chlorotrianisene (HMDB0014414). Jump To Section: IdentificationTaxonomyOntologyPhysical properties ... Inactivation of the uterine estrogen receptor binding of estradiol during P-450 catalyzed metabolism of chlorotrianisene (TACE ... powerful synthetic, non-steroidal estrogen.Chlorotrianisene binds to the estrogen receptor on various estrogen receptor bearing ...
chlorotrianisene | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY
Chlorotrianisene Side Effects - DrugInformer
List of frequently occuring side effects for chlorotrianisene. Sources include the official FAERS database and social media ... Chlorotrianisene Side Effects. Filter Table by Serious Outcome. ×. Filter by Serious Outcome. ... View full report on Chlorotrianisene related hepatic failure Did the author experience hepatic failure while taking tace? ... View full report on Chlorotrianisene related decreased appetite Did the author experience decreased appetite while taking tace ...
ChemIDplus - 6V5034L121 - BFPSDSIWYFKGBC-UHFFFAOYSA-N - Chlorotrianisene [USP:INN:BAN] - Similar structures search, synonyms,...
Tace, FN, Chlorotrianisene, Aventis | DrugInfo.In
Tace, FN, Chlorotrianisene, Aventis. Tace, FN, Chlorotrianisene, Aventis. The drug brand named Tace-FN contains generic salt- ... Tace, Chlorotrianisene, Aventis. The drug brand named Tace contains generic salt-Chlorotrianisene and is manufactured by Sanofi ... G03CA06-Chlorotrianisene.. Generic Salts. Chlorotrianisene. Available types of drugs. N / A. Medical categories. Human Drug. ... G03CA06-Chlorotrianisene. Manufacturers. Sanofi-Aventis. More Drugs. * Tabron, Pfizer. The drug brand named Tabron contains ...
Oestrogens, Nonsteroidal (IARC Summary & Evaluation, Supplement7, 1987)
Chlorotrianisene. A. Evidence for carcinogenicity to animals (inadequate) Chlorotrianisene was tested in only one experiment in ... Chlorotrianisene. CAS No.: 569-57-3. Chem. Abstr. Name:1,1,l"-(1-Chloro-1-ethenyl-2-ylidene)-tris(4-methoxybenzene). ... Synonyms for Chlorotrianisene. * Anisene * Chlorestrolo *Chlorotrianisine * Chlorotrianizen * Chlorotrisin * Chlorotris-(para- ...
Polyestradiol phosphate - Wikipedia
TACE and Adefovir Compared With Transarterial Chemoembolization (TACE) Alone for Hepatitis B Virus (HBV)-Related Unresectable...
Bupropion (Oral Route) Side Effects - Mayo Clinic
Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). The use of alcohol or other medicines that affect the CNS with bupropion may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Bupropion may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. Make sure the doctor knows if you have trouble sleeping, get upset ...
Aplenzin Advanced Patient Information - Drugs.com
Nivolumab in Combination With TACE/TAE for Patients With Intermediate Stage HCC - Full Text View - ClinicalTrials.gov
Bupropion (Oral Route) Before Using - Mayo Clinic
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.. ...
Large-scale prediction and testing of drug activity on side-effect targets. - PubMed - NCBI
d) Chlorotrianisene inhibits platelet aggregation. Two independent experiments (red and blue) shown for chlorotrianisene and ... Chlorotrianisene is only marginally similar to indomethacin, but is (correctly) predicted for COX-1. (d) Sequence similarities ... Hit rates of SEA (red) and 1NN (blue) with s.d. (c) Non-intuitive (chlorotrianisene) and straightforward (medrysone) SEA ... Among these new associations was the prediction that the abdominal pain side effect of the synthetic oestrogen chlorotrianisene ...
Diethylstilbestrol - Wikipedia
Estrobin - Wikipedia
Welsh, Ashton L. (1954). "USE OF SYNTHETIC ESTROGENIC SUBSTANCE CHLOROTRIANISENE (TACE) IN TREATMENT OF ACNE". Archives of ... Chlorotrianisene, and subsequently clomifene and tamoxifen, were derived from it. Estrobin, similarly to other ... Similarly to chlorotrianisene, estrobin behaves a prodrug to a much more potent estrogen in the body. ...
Triphenyliodoethylene - Wikipedia
Ospemifene - DrugBank
Alclometasone - DrugBank
Meyler's Side Effects of Drugs - Elsevier Science & Technology - Literati by Credo
ATC code G03
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Хлоротрианизен and breastfeeding. Are they compatible?
The effect of chlorotrianisene as postpartum lactation suppression on blood coagulation factors. Am J Obstet Gynecol. 1979 ... Utian WH, Begg G, Vinik AI, Paul M, Shuman L. Effect of bromocriptine and chlorotrianisene on inhibition of lactation and serum ... Yuen BH, Pendleton HJ, Blair S. Efficacy of bromocriptine and chlorotrianisene in preventing postpartum lactation. Can Med ...
- Chlorotrianisene (CTA), also known as tri-p-anisylchloroethylene (TACE) and sold under the brand name Tace among others, is a nonsteroidal estrogen related to diethylstilbestrol (DES) which was previously used in the treatment of menopausal symptoms and estrogen deficiency in women and prostate cancer in men, among other indications, but has since been discontinued and is now no longer available. (wikipedia.org)
- Chlorotrianisene, also known as tri-p-anisylchloroethylene (TACE) or as tris(p-methoxyphenyl)chloroethylene, is a synthetic nonsteroidal compound of the triphenylethylene group. (wikipedia.org)
- The drug brand named Tace-FN contains generic salt-Chlorotrianisene and is manufactured by Sanofi-Aventis. (drug-info.in)
- Tace-FN is mainly associated with symptoms and indications-The International Classification of Diseases (ICD)- G03CA06-Chlorotrianisene. (drug-info.in)
- Chlorotrianisene (tace) (fig. Also called an orientation-selective cell. (yogachicago.com)
- Chlorotrianisene (tace) (fig. Found no effect or purkinje phenomenon. (yogachicago.com)
- As an example, chlorotrianisene produces gynecomastia in men, albeit reportedly to a lesser extent than other estrogens, while clomifene and tamoxifen do not and can be used to treat gynecomastia. (wikipedia.org)
- Chlorotrianisene is a nonsteroidal synthetic estrogen. (pharmacycode.com)
- Symptoms warrants it, may not be given to the symphysis, with the initial dissection (fig. Stilbestrol and chlorotrianisene are sometimes palpable but more efficacious than hydrochlorothiazide (fig. 417 figure 11.7 decidua and multi-drug resistant organisms: Ceftriaxone azithromycin empirical treament: Ceftriaxone azithromycin. (bigsurlandtrust.org)
- Stilbestrol and chlorotrianisene are sometimes confused with scotophobia. (ceu.edu)
- Additionally, clomiphene in an array of isomeric ratios (EN:ZU) can be used alone for prevention of osteoporosis, maintenance of a healthful blood lipid profile, and prevention of breast tumors, or to sustain amenorrhea. (justia.com)
- About Clomiphene A selective estrogen receptor modulator (SERM),chlorotrianisene derivative, Ovulation Stimulator ,Fertility agent. (rosheta.com)
- It is a powerful synthetic, non-steroidal estrogen.Chlorotrianisene binds to the estrogen receptor on various estrogen receptor bearing cells. (hmdb.ca)
- For example, the estrogen receptor (ESR1) modulator chlorotrianisene was found to inhibit PTGS1 (COX-1), indeed with an affinity substantially better than its affinity for ESR1. (nih.gov)
- Drugs that modulate the two proteins can share two of chlorotrianisene's adverse reactions, "erythema multiforme" and "oedema", but "rash" and "abdominal pain upper" link only to drugs inhibiting COX-1, and both of these are associated with chlorotrianisene almost uniquely among the estrogen receptor modulators (Figure 2a, Supplementary TableS5). (nih.gov)
- After menopause, when the body no longer produces estrogen, chlorotrianisene is used as a simple replacement of estrogen. (pharmacycode.com)
- Chlorotrianisene is only found in individuals that have used or taken this drug. (hmdb.ca)
- Among these new associations was the prediction that the abdominal pain side effect of the synthetic oestrogen chlorotrianisene was mediated through its newly discovered inhibition of the enzyme cyclooxygenase-1. (nih.gov)
- Among these new associations was the prediction that the abdominal pain side effect of the synthetic oestrogen chlorotrianisene was mediated through its newly discovered inhibition of the enzyme cyclooxygenase-1.The clinical relevance of this inhibition was borne out in whole human blood platelet aggregation assays.This approach may have wide application to de-risking toxicological liabilities in drug discovery. (nih.gov)
- Smurfing is circulating a method used by subjoining some dabrafenib and precursor chemical traffickers to acquire large quantities of chlorotrianisene. (mysignaturewebdesign.com)
- Triamcinolone acetonide and Chlorotrianisene were purchased from the Wako pure chemical process industries. (info-web-directory.com)
- Chlorotrianisene is only marginally similar to indomethacin, but is (correctly) predicted for COX-1. (nih.gov)
- However, Compact Chlorotrianisene disc123 can be indicated on regular hematopoietic stem cells also, and irreversible myeloablative effects of Compact disc123 CAR T-cells had been reported by earlier research (41, 42). (annumed.net)
- Herein, a synopsis can be supplied by us of the use of CAR T-cell therapy in Chlorotrianisene every, emphasizing the primary problems and potential medical strategies in order to promote a standardized group of treatment paradigms for many. (annumed.net)