A naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats. (From J Chromatogr A 1996;741(2):223-31; Biosci Biotechnol Biochem 1996;60(5):765-68).
A genus of perennial herbs used topically and internally. It contains echinacoside, GLYCOSIDES; INULIN; isobutyl amides, resin, and SESQUITERPENES.
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
A publication issued at stated, more or less regular, intervals.
A class of phenolic acids related to chlorogenic acid, p-coumaric acid, vanillic acid, etc., which are found in plant tissues. It is involved in plant growth regulation.
A plant genus of the family CAPRIFOLIACEAE. Members contain iridoid glucosides.
An acid which is found in cinchona bark and elsewhere in plants. (From Stedman, 26th ed)
A flavonol glycoside found in many plants, including BUCKWHEAT; TOBACCO; FORSYTHIA; HYDRANGEA; VIOLA, etc. It has been used therapeutically to decrease capillary fragility.
Hydroxycinnamic acid and its derivatives. Act as activators of the indoleacetic acid oxidizing system, thereby producing a decrease in the endogenous level of bound indoleacetic acid in plants.
A plant genus of the family RUBIACEAE. It is best known for the COFFEE beverage prepared from the beans (SEEDS).
A beverage made from ground COFFEA beans (SEEDS) infused in hot water. It generally contains CAFFEINE and THEOPHYLLINE unless it is decaffeinated.
The dynamic collection of metabolites which represent a cell's or organism's net metabolic response to current conditions.
The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.
Benzoate derivatives substituted by one or more hydroxy groups in any position on the benzene ring.
The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
A major protein fraction of milk obtained from the WHEY.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The parts of a macromolecule that directly participate in its specific combination with another molecule.
Cell-cell junctions that seal adjacent epithelial cells together, preventing the passage of most dissolved molecules from one side of the epithelial sheet to the other. (Alberts et al., Molecular Biology of the Cell, 2nd ed, p22)
Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells, such as ENTEROCYTES. These cells are valuable in vitro tools for studies related to intestinal cell function and differentiation.
Proteins that take part in the formation or structure of TIGHT JUNCTIONS.
Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.
A MARVEL domain protein that plays an important role in the formation and regulation of the TIGHT JUNCTION paracellular permeability barrier.
A 195-kDa zonula occludens protein that is distinguished by the presence of a ZU5 domain at the C-terminal of the molecule.
A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
Atomic species differing in mass number but having the same atomic number. (Grant & Hackh's Chemical Dictionary, 5th ed)
Uptake of substances through the lining of the INTESTINES.
The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.

Irreversible inhibition of human immunodeficiency virus type 1 integrase by dicaffeoylquinic acids. (1/190)

Human immunodeficiency virus type 1 (HIV-1) and other retroviruses require integration of a double-stranded DNA copy of the RNA genome into the host cell chromosome for productive infection. The viral enzyme, integrase, catalyzes the integration of retroviral DNA and represents an attractive target for developing antiretroviral agents. We identified several derivatives of dicaffeoylquinic acids (DCQAs) that inhibit HIV-1 replication in tissue culture and catalytic activities of HIV-1 integrase in vitro. The specific step at which DCQAs inhibit the integration in vitro and the mechanism of inhibition were examined in the present study. Titration experiments with different concentrations of HIV-1 integrase or DNA substrate found that the effect of DCQAs was exerted on the enzyme and not the DNA. In addition to HIV-1, DCQAs also inhibited the in vitro activities of MLV integrase and truncated variants of feline immunodeficiency virus integrase, suggesting that these compounds interacted with the central core domain of integrase. The inhibition on retroviral integrases was relatively specific, and DCQAs had no effect on several other DNA-modifying enzymes and phosphoryltransferases. Kinetic analysis and dialysis experiments showed that the inhibition of integrase by DCQAs was irreversible. The inhibition did not require the presence of a divalent cation and was unaffected by preassembling integrase onto viral DNA. The results suggest that the irreversible inhibition by DCQAs on integrase is directed toward conserved amino acid residues in the central core domain during catalysis.  (+info)

Identification of protein components of the microsomal glucose 6-phosphate transporter by photoaffinity labelling. (2/190)

The glucose-6-phosphatase system catalyses the terminal step of hepatic glucose production from both gluconeogenesis and glycogenolysis and is thus a key regulatory factor of blood glucose homoeostasis. To identify the glucose 6-phosphate transporter T1, we have performed photoaffinity labelling of human and rat liver microsomes by using the specific photoreactive glucose-6-phosphate translocase inhibitors S 0957 and S 1743. Membrane proteins of molecular mass 70, 55, 33 and 31 kDa were labelled in human microsomes by [3H]S 0957, whereas in rat liver microsomes bands at 95, 70, 57, 54, 50, 41, 33 and 31 kDa were detectable. The photoprobe [3H]S 1743 led to the predominant labelling of a 57 kDa and a 50 kDa protein in the rat. Stripping of microsomes with 0.3% CHAPS retains the specific binding of T1 inhibitors; photoaffinity labelling of such CHAPS-treated microsomes resulted in the labelling of membrane proteins of molecular mass 55, 33 and 31 kDa in human liver and 50, 33 and 31 kDa in rat liver. Photoaffinity labelling of human liver tissue samples from a healthy individual and from liver samples of patients with a diagnosed glycogen-storage disease type 1b (GSD type 1b; von Gierke's disease) revealed the absence of the 55 kDa protein from one of the patients with GSD type 1. These findings support the identity of the glucose 6-phosphate transporter T1, with endoplasmic reticulum protein of molecular mass 50 kDa in rat liver and 55 kDa in human liver.  (+info)

Natural antioxidant, chlorogenic acid, protects against DNA breakage caused by monochloramine. (3/190)

Chlorogenic acid prevented a stepwise conversion of plasmid pUC18 DNA, from I-->form II-->form III, induced by 3 mM monochloramine with a half inhibition of 67.4 microM. Chlorogenic acid reacted with monochloramine in a time-dependent manner, and the reaction rate increased with decreasing pH. These results suggest that chlorogenic acid prevents genotoxicity of monochloramine in gastric mucosa.  (+info)

The small intestine can both absorb and glucuronidate luminal flavonoids. (4/190)

We have studied the perfusion of the jejunum and ileum in an isolated rat intestine model with flavonoids and hydroxycinnamates and the influence of glycosylation on the subsequent metabolism. Flavone and flavonol glucosides and their corresponding aglycones are glucuronidated during transfer across the rat jejunum and ileum and this glucuronidation occurs without the need for gut microflora. Furthermore, this suggests the presence of glycosidases as well as UDP-glucuronyl transferase in the jejunum. In contrast, quercetin-3-glucoside and rutin are mainly absorbed unmetabolised. The results suggest that the more highly reducing phenolics are absorbed predominantly as glucuronides (96.5%+/-4.6) of the amount absorbed, whereas monophenolic hydroxycinnamates and monophenolic B-ring flavonoids are less predisposed to glucuronidation and higher levels of aglycone (88.1%+/-10.1) are detected on absorption through both the jejunum and ileum.  (+info)

Expression of tryptophan decarboxylase and tyrosine decarboxylase genes in tobacco results in altered biochemical and physiological phenotypes. (5/190)

The substrate specificity of tryptophan (Trp) decarboxylase (TDC) for Trp and tyrosine (Tyr) decarboxylase (TYDC) for Tyr was used to modify the in vivo pools of these amino acids in transgenic tobacco. Expression of TDC and TYDC was shown to deplete the levels of Trp and Tyr, respectively, during seedling development. The creation of artificial metabolic sinks for Trp and Tyr also drastically affected the levels of phenylalanine, as well as those of the non-aromatic amino acids methionine, valine, and leucine. Transgenic seedlings also displayed a root-curling phenotype that directly correlated with the depletion of the Trp pool. Non-transformed control seedlings could be induced to display this phenotype after treatment with inhibitors of auxin translocation such as 2,3,5-triiodobenzoic acid or N-1-naphthylphthalamic acid. The depletion of aromatic amino acids was also correlated with increases in the activities of the shikimate and phenylpropanoid pathways in older, light-treated transgenic seedlings expressing TDC, TYDC, or both. These results provide in vivo confirmation that aromatic amino acids exert regulatory feedback control over carbon flux through the shikimate pathway, as well as affecting pathways outside of aromatic amino acid biosynthesis.  (+info)

Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression. (6/190)

Commercially available St. John's wort (Hypericum perforatum) extracts, preparations that are used in the treatment of depression, were examined for the potential to inhibit human cytochrome P450 (CYP) enzyme activities, specifically CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4. Crude extracts demonstrated inhibition of each of these five enzymes, with CYP2D6, CYP2C9, and CYP3A4 being more sensitive than CYP1A2 and CYP2C19. Extracts were fractionated by HPLC, and each of the fractions was tested for inhibition of these five CYPs to identify individual constituents with inhibitory activity. Several fractions were shown to possess inhibitory activity, including the fractions containing hyperforin (the putative active antidepressant constituent), I3,II8-biapigenin, and hypericin. Hyperforin and I3,II8-biapigenin were isolated from the extract, and inhibition constants for the five CYP activities were measured. In addition, three other constituents, hypericin, quercetin, and chlorogenic acid, were tested for inhibitory activity toward the CYP enzymes. The flavonoid compound I3,II8-biapigenin was shown to be a potent, competitive inhibitor of CYP3A4, CYP2C9, and CYP1A2 activities with K(i) values of 0.038, 0.32, and 0.95 microM, respectively. Hyperforin was a potent noncompetitive inhibitor of CYP2D6 activity (K(i) = 1.5 microM) and competitive inhibitor of CYP2C9 and CYP3A4 activities (K(i) = 1.8 and 0.48 microM, respectively). Hypericin also demonstrated potent inhibition of several CYP activities. These in vitro data indicate that St. John's wort preparations contain constituents that can potently inhibit the activities of major human drug-metabolizing enzymes and suggest that these preparations should be examined for potential pharmacokinetic drug interactions in vivo.  (+info)

Inhibition of NFkappaB by methyl chlorogenate from Eriobotrya japonica. (7/190)

Methylchlorogenic acid (MC) is one of the main components in the leaves of Eriobotrya japonica. We previously reported that MC is the most potent antioxidant among several components of Eriobotrya japonica, and its antioxidant activity is stronger than that of chlorogenic acid. Antioxidants are expected to inhibit redox-sensitive NFkappaB activation since NFkappaB is readily influenced by cellular oxidative state. Based on these findings, in vivo experiments with MC were conducted to determine its ability to downregulate the NFkappaB activation in mouse liver. Results clearly showed that MC is a potent suppressor of BHP-induced NFkappaB activation. We observed a significant reduction by MC on BHP-induced translocation of p65 subunit of NFkappaB. This may be due to formation of p50/p65 heterodimer, which is mainly inducible NFkappaB. MC slightly blocked the BHP-induced IkappaB alpha degradation. There is a possibility of IkappaB alpha resynthesis via activated NFkappaB during a 5 h waiting period following BHP injection. The present results suggest that MC may inhibit NFkappaB activation, exhibiting its ability to downregulate the NFkappaB-dependent gene expression. Thus, it can be expected that MC may have potential for therapeutic intervention on various NFkappaB-dependent pathological conditions such as inflammatory or possibly mutagenic processes.  (+info)

Naturally occurring polyphenolic antioxidants modulate IgE-mediated mast cell activation. (8/190)

Reactive oxygen species (ROS) are known to modulate activities of a host of kinases, phosphatases and transcription factors. Rutin and chlorogenic acid (CGA) are the major polyphenolic antioxidants present in the small molecular fraction of smokeless tobacco leaf extracts, as ascertained by reverse-phase high-pressure liquid chromatography (HPLC) and mass spectrometry. Levels of intracellular ROS in resting versus antigen-immunoglobulin E (IgE)-challenged murine mast cells were measured at 510 nm by fluorescence-activated cell sorting (FACS) using carboxy-dichlorofluorescein (DCFH-DA). Enhanced ROS production was observed in IgE-sensitized mast cells following antigenic challenge. Rutin and CGA reduced ROS levels in antigen-IgE-activated mast cells. Concomitantly, they also profoundly inhibited histamine release by these activated mast cells. In contrast, rutin and CGA augmented the inducible cytokine messages, i.e. interleukin (IL)-10, IL-13, interferon-gamma (IFN-gamma), IL-6 and tumour necrosis factor-alpha (TNF-alpha) in IgE-sensitized mast cells following antigen challenge. This study indicates that tobacco polyphenolic antioxidants that quench intracellular ROS, differentially affect two effector functions of antigen-IgE-activated mast cells. This model system may be employed to determine the molecular target of polyphenols. The potential role of these polyphenolic antioxidants on IgE-mediated allergy in vivo depends on a balance of their differential effects on mast cell activation.  (+info)

Chlorogenic acid is an ester of caffeic acid and quinic acid. Chlorogenic acid is the major polyphenolic compound in coffee, isolated from the leaves and fruits of dicotyledonous plants. This compound, long known as an antioxidant, also slows the release of glucose into the bloodstream after a meal. Coffee is a complex mixture of chemicals that provides significant amounts of chlorogenic acid. The chlorogenic acid content of a 200 ml (7-oz) cup of coffee has been reported to range from 70-350 mg, which would provide about 35-175 mg of caffeic acid. The results of epidemiological research suggest that coffee consumption may help prevent several chronic diseases, including type 2 diabetes mellitus, Parkinsons disease and liver disease (cirrhosis and hepatocellular carcinoma). Most prospective cohort studies have not found coffee consumption to be associated with significantly increased cardiovascular disease risk. However, coffee consumption is associated with increases in several cardiovascular ...
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The absorption and metabolism in the small intestine of chlorogenic acid (5-O-caffeoylquinic acid), the main phenolic acid in the human diet, and of caffeic acid were studied in rats in order to determine whether chlorogenic acid is directly absorbed
The non-covalent interactions between the monomeric phenolic compound chlorogenic acid (5-CQA) and bovine serum albumin (BSA), lysozyme, and α-lactalbumin were characterized, and their effect on protein properties was examined. 5-CQA had a low affinity for all three proteins, and these interactions seemed to show a negative cooperativity. 5-CQA-BSA binding decreased with increasing temperature, whereas pH (pH 3.0 compared to pH 7.0) and ionic strength had no pronounced effect. At high 5-CQA/protein molar ratios, both the denaturation enthalpy and temperature of BSA increased; however, covalent bonds were created at high temperatures. The presence of 5-CQA had no effect on the solubility of BSA and α-lactalbumin as a function of pH, whereas it decreased lysozyme solubility at alkaline pH due to covalent interactions. These results indicate that the non-covalent interactions with 5-CQA do not have pronounced effects on the functional properties of globular proteins in food systems. ...
To investigate the mechanism of the combined effects of chlorogenic acid (CGA) and caffeine on lipid metabolism in high-fat diet-induced obese mice, eighty female ICR mice were randomly divided into eight groups and fed with a high-fat diet with/without CGA and/or caffeine for 14 weeks. The combination of CG
The leaves of globe artichoke and cultivated cardoon (Cynara cardunculus L.) have significant pharmaceutical properties, which mainly result from their high content of polyphenolic compounds such as monocaffeoylquinic and dicaffeoylquinic acid (DCQ), and a range of flavonoid compounds. Hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase (HQT) encoding genes have been isolated from both globe artichoke and cultivated cardoon (GenBank accessions DQ915589 and DQ915590, respectively) using CODEHOP and PCR-RACE. A phylogenetic analysis revealed that their sequences belong to one of the major acyltransferase groups (anthranilate N-hydroxycinnamoyl/benzoyltransferase). The heterologous expression of globe artichoke HQT in E. coli showed that this enzyme can catalyze the esterification of quinic acid with caffeoyl-CoA or p-coumaroyl-CoA to generate, respectively, chlorogenic acid (CGA) and p-coumaroyl quinate. Real time PCR experiments demonstrated an increase in the expression level of HQT in UV-C treated
Rich in Phenolic Antioxidant Compounds. Researchers at the US Agricultural Service in Beltsville, Maryland, have found that eggplants are rich sources of phenolic compounds that function as antioxidants. Plants form such compounds to protect themselves against oxidative stress from exposure to the elements, as well as from infection by bacteria and fungi.. The good news concerning eggplant is that the predominant phenolic compound found in all varieties tested is chlorogenic acid, which is one of the most potent free radical scavengers found in plant tissues. Benefits attributed to chlorogenic acid include antimutagenic (anti-cancer), antimicrobial, anti-LDL (bad cholesterol) and antiviral activities.. ARS researchers studied seven eggplant cultivars grown commercially in the U.S. and a diverse collection of exotic and wild eggplants from other counties. In addition to chlorogenic acid, they found 13 other phenolic acids present at significantly varying levels in the commercial cultivars, ...
To read the authors abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. NOTE: Chlorogenic acid and caffeic acid are inhibitors of DNA methylation. Argan oil is a source of chlorogenic acid and caffeic acid. Green coffee bean extract contains chlorogenic […]. View Post ...
Apples contain a large concentration of flavonoids, as well as a variety of other phytochemicals, and the concentration of these phytochemicals may depend on many factors, such as cultivar of the apple, harvest and storage of the apples, and processing of the apples. The concentration of phytochemicals also varies greatly between the apple peels and the apple flesh.. Some of the most well studied antioxidant compounds in apples include quercetin-3-galactoside, quercetin-3-glucoside, quercetin-3-rhamnoside, catechin, epicatechin, procyanidin, cyanidin-3-galactoside, coumaric acid, chlorogenic acid, gallic acid, and phloridzin. Recently researchers have examined the average concentrations of the major phenolic compounds in six cultivars of apples. They found that the average phenolic concentrations among the six cultivars were: quercetin glycosides, 13.2 mg/100 g fruit; vitamin C, 12.8 mg/100 g fruit; procyanidin B, 9.35 mg/100 g fruit; chlorogenic acid, 9.02 mg/100 g fruit; epicatechin, 8.65 ...
Apples contain a large concentration of flavonoids, as well as a variety of other phytochemicals, and the concentration of these phytochemicals may depend on many factors, such as cultivar of the apple, harvest and storage of the apples, and processing of the apples. The concentration of phytochemicals also varies greatly between the apple peels and the apple flesh.. Some of the most well studied antioxidant compounds in apples include quercetin-3-galactoside, quercetin-3-glucoside, quercetin-3-rhamnoside, catechin, epicatechin, procyanidin, cyanidin-3-galactoside, coumaric acid, chlorogenic acid, gallic acid, and phloridzin. Recently researchers have examined the average concentrations of the major phenolic compounds in six cultivars of apples. They found that the average phenolic concentrations among the six cultivars were: quercetin glycosides, 13.2 mg/100 g fruit; vitamin C, 12.8 mg/100 g fruit; procyanidin B, 9.35 mg/100 g fruit; chlorogenic acid, 9.02 mg/100 g fruit; epicatechin, 8.65 ...
Its likely. Additional studies support this possibility. One observational study of 28,000 postmenopausal women actually found that decaffeinated coffee was more protective than regular coffee - which suggests that the caffeine in coffee might be increasing risk, while the phytochemicals decrease risk.4 Chlorogenic acid and trigonelline, two of the major phytochemicals in coffee, have been shown to decrease blood glucose and insulin concentrations in the blood compared to placebo after ingesting sugar, so these phytochemicals likely increase insulin sensitivity.5 It is doubtful that coffee would offer any additional protection on top of a nutrient dense diet - the responsible phytochemicals can be obtained from other plant foods and the diet would not be so lacking in antioxidants. For example, blueberries contain the antioxidant chlorogenic acid, and the phytoestrogen trigonelline is also found in peas, lentils, soybeans, and sunflower seeds. 6-8 The only reason coffee is beneficial is because ...
Thank you for the Goji berry information, Trevor. Do we have to be wary of all food used in Eastern herbal medicines? I will stop consuming my berries until I am further along the MP. I rather liked the fact that they are supposed to be so high in iron, help control blood sugar levels and support liver function, but at the same time, I do not want to mess around with modulating my immune system at this point of the MP. As I am still using my natural progesterone cream, it would be wise not to add more to the mix. Other than red meat, what are the best sources of iron from food? I know about raisins and chocolate, but prefer not to consume too much in the way of sugary foods and my stomach does not do well with diabetic products.Also, how can we be sure that other food products we are consuming also do not modulate the immune system to some extent ...
|i|Auricularia delicata|/i|, an edible mushroom, has been used as a traditional medicine in Manipur, India, for various gastrointestinal and liver ailments. Thi...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sigma-Aldrich offers abstracts and full-text articles by [Zheng Ruan, Shiqiang Liu, Yan Zhou, Shumei Mi, Gang Liu, Xin Wu, Kang Yao, Houssein Assaad, Zeyuan Deng, Yongqing Hou, Guoyao Wu, Yulong Yin].
GSD-1 (glycogen storage disease type 1) is caused by an inherited defect in glucose-6-phosphatase activity, resulting in a massive accumulation of hepatic glycogen content and an induction of de novo lipogenesis. The chlorogenic acid derivative S4048 is a pharmacological inhibitor of the glucose 6-phosphate transporter, which is part of glucose-6-phosphatase, and allows for mechanistic studies concerning metabolic defects in GSD-1. Treatment of mice with S4048 resulted in an ~60% reduction in blood glucose, increased hepatic glycogen and triacylglycerol (triglyceride) content, and a markedly enhanced hepatic lipogenic gene expression. In mammals, hepatic expression of lipogenic genes is regulated by the co-ordinated action of the transcription factors SREBP (sterol-regulatory-element-binding protein)-1c, LXRα (liver X receptor α) and ChREBP (carbohydrate-response-element-binding protein). Treatment of Lxra−/− mice and Chrebp−/− mice with S4048 demonstrated that ChREBP, but not LXRα, ...
h-SUN+ is green coffee with ling zhi, maitake, acai and protein. It contains a variety of high-quality raw materials. In addition to chlorogenic acid from the green coffee, it contains choline (84 mg per serving), which contributes to the healthy metabolism of fat. An interest in exercise and feeling comfortable with your weight are important in making you feel good. Our goal is to help you achieve this. h-SUN+ has been developed with the support of experts, and works holistically to optimise your bodys functions. Keep an eye on your figure with h-SUN+, your ideal companion for a positive start to the day - or to keep you going! Stay on the safe side with a cup of h-SUN+ a day. The perfect combination of ingredients makes h-SUN+ UNIQUE! ...
From a metabolic point of view, Animal Cuts, is stacked with only the most potent tea extracts. From green tea extract to oolong tea extract to white tea extract to black tea extract, it´s all covered here. These concentrated tea extracts have all been standardized for their potent polyphenol content, including EGCG as well as various other powerful catechins that work synergistically to raise your body´s core metabolism. An increase in core metabolism means an increase in the rate at which your body converts food that is eaten into energy. In short, a faster metabolism equates to less food being stored as bodyfat. Coffee bean extract is also added for its potent Polyphenol content which includes the metabolic boosters - caffeic and chlorogenic acid. Such factors can be the difference in giving your metabolism the kickstart it needs to begin really processing bodyfat. ...
oleic acid, palmitic acid, stearic acid, linoleic acid, linolenic acid, squalene, hydroxytyrosol, tyrosol, oleuropein, ligstroside, elenolic acid, acetoxy-pinoresenol, oleocanthal, α-tocopherol, herniarin, hyperoside, umbelliferone, methylumbelliferone, caffeic acid, chlorogenic acid, quercetin, rutin, flavanone, isorhamnetin, quercimeritin, anthemic acid, choline, triacontane, patuletin, patulitrin, apigetrin, apigenin-7-glucoside, apigenin-7-apiosylglucoside, luteolin-7-glucoside, apigetrin-7-acetylglucoside, luteolin-4-glucoside, luteolin, patuletin, matricin, matricarin, galacturonic acid, d-limonene, citronellol, geraniol, myrcene, linalool, α-pinene, sabinene, β-phellandrene, geranial, neral, decanal, citronellal, (Z)-β-ocimene, β-pinene, valencene, β-elemene, terpinolene, dodecanal, γ-terpinene, β-sinensal, α-sinensal, δ-cadinene, α-copaene, γ-muurolene, nerol, δ-3-carene, (Z)-3-hexenol, perillaldehyde, octanol, cis-sabinene hydrate, undecanal, nonadecane, heneicosane, ...
The interaction of ten natural polyphenolic compounds (chlorogenic acid, apigenin, catechin, epicatechin, flavanone, flavone, quercetin, rutin, vicenin-2 and vitexin) with human serum albumin and...
CGAs, phenolic acids, and late-appearing metabolites all increased with increasing ingested dose. Hence, the sum of area under the curve was significantly higher for the medium to low dose, and high to medium dose, by 2.23- and 2.38-fold, respectively. CGAs were not well absorbed in their intact form, regardless of the dose. CGA and phenolic acids appeared rapidly in plasma, indicating an early absorption in the gastrointestinal tract. Late-appearing metabolites were the most abundant, regardless of the dose. ...
Antioxidant beverage. With other natural flavors. 5 calories per 8 oz serving. 1 g sugar. No artificial sweeteners. Sweet by nature. Antioxidant infused. Fan-favored flavor that tastes like the quarterback just kissed the prom queen. The most popular flavors in school are holding hands in the hallway and locking lips in the Library. They belong together. This couple is downright algebraic. Average 1/2 iced tea and 1/2 lemonade. Add antioxidants and subtract artificial sweeteners. Multiply by 5 calories and 1 gram of sugar, and it equals one tasty flavor. And you thought youd never use math again. Facebook. Twitter. Instagram. Pinterest. (hashtag)DrinkBai. DrinkBai.com. Contains 4% juice. 5 calories per serving. Excellent source of vitamin C. 1 net carb per serving (Erythritol carbs have no calories or effect on blood sugar). Antioxidants (per bottle): 35 mg vitamin C. Also contains 100 mg polyphenols & chlorogenic acid from coffeefruit extract and white tea extract. Natures Caffeine: 35 mg per ...
Chlorogenic acids are among the most abundant phenolics found in the human diet. Of these, the mono-caffeoylquinic acids are the predominant phenolics found in fruits, such as apples and pears, and products derived from ...
Chlorogenic acids are among the most abundant phenolics found in the human diet. Of these, the mono-caffeoylquinic acids are the predominant phenolics found in fruits, such as apples and pears, and products derived from ...
Overview. Plexus Slim is a powdered dietary supplement that claims to help with weight loss. A major pro of this supplement it that it is stimulant and thermogenic free, and contains all natural ingredients. This means that it may be a safer option for diabetics and those who are stimulant sensitive. To use Plexus Slim, you simply mix the powder with water and drink it thirty minutes prior to any meal, making it easy and convenient. The major ingredient used to assist with body fat loss is chlorogenic acid, an antioxidant that may block carbohydrate absorption and assist the body in the detox process. The other major ingredient found in this product is oxypregnane steroid glycoside, a compound known to suppress appetite by sending the full signal to the brain.. Our experts have rated several weight loss diets and have found that the 18Shake Diet was the most effective. It offers a combination of a fat burning diet pill and an appetite suppressing meal replacement. Both have only natural ...
Dried prunes contain approximately 6.1g of dietary fibre per 100g, although prune juice is devoid of fibre as it is filtered before bottling. Prunes are good source of energy in the form of simple sugars, but they do not give rise to a rapid rise in blood sugar concentration, possibly due to their high fibre, fructose, and sorbitol content. Prunes contain large amounts of unique phytonutrients (essential nutrients that come from plants) called neochlorogenic and chlorogenic acids. These substances are classified as phenols, which are chemicals found in nearly all food types and are antioxidants. Oxidation is the interaction between oxygen molecules and any other substance, including living tissue. It is constantly occurring in the cells of our body but oxidation reactions can also cause damage because at a molecular level they can give rise to free radicals, which are atoms or groups of atoms with an odd number of electrons, which can cause damage to cells that in turn can lead to chronic ...
RESULTS:. We observed that increased production of hepatic H6PDH in db/db mice was paralleled by upregulation of hepatic G6PT production and responded to elevated circulating levels of corticosterone. Treatment of db/db mice with the glucocorticoid antagonist RU486 markedly reduced production of both H6PDH and 11β-HSD1 and improved hyperglycaemia and insulin resistance. The reduction of H6PDH and 11β-HSD1 production by RU486 was accompanied by RU486-induced suppression of hepatic G6pt (also known as Slc37a4) mRNA. Incubation of mouse primary hepatocytes with corticosterone enhanced G6PT and H6PDH production with corresponding activation of 11β-HSD1 and PEPCK: effects that were blocked by RU486. Knockdown of H6pd by small interfering RNA showed effects comparable with those of RU486 for attenuating the corticosterone-induced H6PDH production and 11ß-HSD1 reductase activity in these intact cells. Addition of the G6PT inhibitor chlorogenic acid to primary hepatocytes suppressed H6PDH production ...
Nutrients like vitamins A and C, fiber, chlorogenic acid and neochlorogenic acid, and phtyosterols play a big role in the health benefits of peaches.
Nothopuginae con los tarsos II y III con 1.2/2.4 espinas y con los tarsos IV con 2.2.2/2.4 espinas. Dedo m vil de los quel ceros sin dien medio; no hay diente basal interno. Dedo fijo de los quel ceros con 2 anteriores. [Nothopuginae with tarsi II and III with 1.2/2.4 spines and tarsus IV with 2.2.2/2.4 spines. Movable finger of the chelicera without intermediate tooth; no internal basal tooth. Fixed finger of the chelicera with 2 anterior teeth.]. ...
[Objective] To establish a method for determining contents of chlorogenic acid in different organs from Taraxacum mongolicum by HPLC.[Method] The HPLC was carried out with Shim-pack VP-ODS column(4.6 mm×150.0 mm,5 μm) using mixture of methanol and 0.4 % phosphoric acid solution in different ratio as mobile phase.Other conditions were: flow rate of 1.0 ml/min,detection wavelength of 326 nm,column temperature of 40 ℃ and sampling amount of 20 μl.[Result] When the concentration of chlorogenic acid ranged from 0.791 2 to 79.120 0 μg/ml,the linear relationship between concentration and peak area was good(r=0.999 8).The recovery was 98.00%-101.50%.Leaves、roots、flowers and scapes of Taraxacum mongolicum were 1.212,0.536,0.448 and 0.417 mg/g in chlorogenic acid,respectively.[Conclusion] The method established in this work was a rapid and accurate method for determining chlorogenic acid from Taraxacum mongolicum.Leaf of Taraxacum mongolicum was highest in chlorogenic acid,which provided basis for
Staherb Natural Ingredients plant extract Dihydromyricetin Chlorogenic Acid corosolic acid Amygdalin luteolin Ursolic acid Rosmarinic acid Magnolol Emodin Apigenin Grape Seed P.E.
Life Extension CoffeeGenic Green Coffee Extract 400mg 90 Vegetable Capsules People who take extraordinary steps to limit their carbohydrate exposure may still be experiencing higher-than-desired blood sugar throughout the day. The reason? Blood sugar can surge to dangerously high levels following meals that can last for hours and even the entire day! Studies show even in people with normal fasting glucose, gaining control of after-meal surges may provide additional support for cardiovascular and metabolic health. To address this widespread problem, a natural compound is now available called CoffeeGenic™ Green Coffee Extract. 400 mg of this next-generation glucose control compound was shown to induce a remarkable 24% drop in after-meal blood sugar after 30 minutes while 200 mg generated a 14% drop. At the core of CoffeeGenic™ Green Coffee Extracts power to favorably modulate after-meal glucose levels is chlorogenic acid, a polyphenol found in the green coffee bean. Chlorogenic acid has
Life Extension CoffeeGenic Green Coffee Extract 400mg 90 Vegetable Capsules People who take extraordinary steps to limit their carbohydrate exposure may still be experiencing higher-than-desired blood sugar throughout the day. The reason? Blood sugar can surge to dangerously high levels following meals that can last for hours and even the entire day! Studies show even in people with normal fasting glucose, gaining control of after-meal surges may provide additional support for cardiovascular and metabolic health. To address this widespread problem, a natural compound is now available called CoffeeGenic™ Green Coffee Extract. 400 mg of this next-generation glucose control compound was shown to induce a remarkable 24% drop in after-meal blood sugar after 30 minutes while 200 mg generated a 14% drop. At the core of CoffeeGenic™ Green Coffee Extracts power to favorably modulate after-meal glucose levels is chlorogenic acid, a polyphenol found in the green coffee bean. Chlorogenic acid has
Green, or unroasted, coffee beans can produce a substantial decrease in body weight in a relatively short period of time!. The most recent study on green coffee bean was published in January 2012 in the Diabetes, Metabolic Syndrome and Obesity journal. The researchers followed a group of 16 adults who supplemented with a special green coffee bean extract of chlorogenic acids at different dosages for 12 weeks. All 16 adults were considered overweight, as demonstrated by a BMI of greater than 25 (a normal BMI is between 18.5 and 25).. The extract the researchers used contained an ingredient called GCA, which contains a standard green coffee extract of total chlorogenic acids and other hydroxycinnamic acids that have been known to have antioxidant health benefits. The subjects lost an average of almost 18 pounds - this was 10% of their overall body weight and 4.4% of their overall body fat.. ...
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What is Hoodia? Nopal Opuntia Hoodia is a succulent plant found in the Kalahari desert of South Africa. The genus encompasses a number of varietie ...
Low prices on Green Coffee Bean Extract! Helps improve glycemic control and promotes weight loss*. Studies show a positive correlation between high coffee consumption and improved glycemic control, which may help with weight loss. The beans (or seeds) found in the berries of coffee trees contain high levels of chlorogenic acid. Chlorogenic acid works in two ways.
Apricot (Prunus armeniaca L.) leaves were studied to assess the potential of apricot leaves for future studies and their applications in nutraceutical and bioactive functional ingredients. The changes in the phenolic profile, carotenoids, pigments and antioxidant potential were studied at four maturation stages. Polyphenols and carotenoids were studied using reversed-phase HPLC-DAD. Pigments, total phenolic contents and radical scavenging activity were also measured. Results revealed twelve phenolic compounds in the apricot leaves. The major phenolic compounds were 3-O-caffeoylquinic acid (14.6-49.6 mg/g), 4-O-caffeoylquinic acid (0.56-7.5 mg/g), 5-O-caffeoylquinic acid (5.6-25.7 mg/g) and quercetin-3-O-glucosides (8.6-19.9 mg/g), while others include caffeic acid and derivatives of coumaric acid and kaempferol. Significant changes were observed in polyphenolic compounds during maturation. Lutein (56.7-65.7 µg/g), neoxanthin (0.66-4.79 µg/g), 5,6-epoxy-α-carotene (5.89-7.9 µg/g), and β-carotene (12
|p|Svetol is a vital ingredient to successful weight loss with green coffee|br /|• Pure and concentrated source of chlorogenic acid|br /|• Chlorogenic acid reduces absorption of fat from food consumption and also stimulates metabolism of fat|/p|
Twenty studies worldwide show that coffee, both regular and decaf, lowers the risk for Type 2 diabetes, in some studies by as much as 50 percent. Researchers say that is probably because chlorogenic acid, one of the many ingredients in coffee, slows uptake of glucose (sugar) from the intestines. (Excess sugar in the blood is a hallmark of diabetes.) Chlorogenic acid may also stimulate GLP-1, a chemical that boosts insulin, the hormone that escorts sugar from the blood into cells. Yet another ingredient, trigonelline, a precursor to vitamin B-3, may also help slow glucose absorption.. For both heart disease and stroke, recent studies are reassuring that frequent coffee consumption does not increase risk. In fact, coffee may - repeat, may - slightly reduce the risk of stroke. A study published in March in the journal Circulation looked at data on more than 83,000 women over 24 years. It showed that those who drank two to three cups of coffee a day had a 19 percent lower risk of stroke than those ...
Studies show that at least five compounds in coffee help reduce cancer risk:. Chlorogenic acid - This antioxidant compound is the major phenol in coffee. Its technically an ester formed between quinic acid and caffeic acid. Caffeic acid is its main component; lab studies show it increases self-destruction of cancer cells and reduces inflammation. Chlorogenic acids antioxidants may be slightly lower in decaf and in instant coffee, but theyre still abundant. Quinic acid contributes to the acidic taste of coffee and is another phytochemical with antioxidant benefits.. Cafestol and kahweol - These fat-soluble compounds are extracted from coffees oils during brewing and are most available in unfiltered coffee (as in French press or boiled coffee; to drink more of these compounds, dont use paper filters). Studies suggest kahweol and cafestol stimulate enzymes that neutralize carcinogens and block the proteins that activate carcinogens.. Caffeine - Everyone knows caffeine acts as a stimulant. Its ...
Lee Rannals for redOrbit.com - Your Universe Online. Drinking a few cups of coffee everyday may actually help reduce the risk of developing type 2 diabetes.. Research published by the Institute for Scientific Information on Coffee, a not-for-profit organization devoted to the study and disclosure of science related to coffee and health, found that drinking three to four cups of coffee per day is associated with a 25 percent lower risk of developing type 2 diabetes.. Although the study suggests an association between moderate coffee consumption, and reduced risk of diabetes, the researchers said the clinical intervention trials are required to study the effect in a controlled setting.. One study tested glucose and insulin after an oral glucose tolerance test with 12 grams of decaffeinated coffee, 1 gram of chlorogenic acid, 500 milligrams of trigonelline, or a placebo. This study saw that chlorogenic acid and trigonelline reduced early glucose and insulin responses, and contributed to the ...
Nettle root contains sterols including beta-sitosterol, and lignans, such as pinoresinol, secoisolariciresinol, dehydroconiferyl alcohol and neo-olivil. The triterpenes, oleanolic acid and ursolic acid, and their derivatives, and a lectin mixture known as Urtica dioica agglutinin (UDA) are also present. Root extracts may be standardised to its content of beta-sitosterol, scopoletin and amino acids (The United States Ph 32).. The leaves contain flavonoids, mainly kaempferol, isorhamnetin and quercetin glycosides, and caffeic acid derivatives. Extracts may be standardised to caffeoylmalic acid and chlorogenic acid expressed as chlorogenic acid (British Ph 2009, European Ph, 6th ed., 2008 and Supplements 6.1, 6.2, 6.3 and 6.4). Note that histamine, formic acid, acetylcholine, acetic acid and 5-hydroxytryptamine, which form the sting when the fresh leaf is touched, are denatured during drying and processing.. ...
0095] In vivo efficacy studies of QA in the rat. There are two physiological factors regarding the natural forms of QA as the active ingredients of water extracts of Cats Claw such as C-MED-100® or ACTIVAR AC-11® which, in turn, might result in quite different biological responses when administered in vitro or in vivo. Firstly, there was the pH=1 of the stomach that we have shown is strong enough to hydrolyze any QA esters present in C-MED-100® to QA (Tables 3 and 5). Secondly, the microflora of the digestive tract of mammals are well known to both synthesize and metabolically convert QA to other analogs such as chlorogenic acid, ferrulic acid, shikimic acid, cinnamonic acid, and benzoic acid (Seifter E, et al. 1971. Nutritional response to feeding L-phenylacetic, shikimic and D-quinic acids in weanling rats. J Nutr 101(6): 747-54; Gonthier M P, et al. 2003. Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in rats. J Nutr 133(6): 1853-63). These well ...
Staherb Natural Ingredients plant extract Dihydromyricetin Chlorogenic Acid corosolic acid Amygdalin luteolin Ursolic acid Rosmarinic acid Magnolol Emodin Apigenin Grape Seed P.E., Chlorogenic Acid
Sigma-Aldrich offers abstracts and full-text articles by [Hilda E Ghadieh, Zachary N Smiley, Melissa W Kopfman, Mona G Najjar, Michael J Hake, Sonia M Najjar].
Pemanfaatan daun kopi robusta (Coffea canephora Peirre ex Froehner) masih sangat terbatas, daun kopi robusta kaya akan senyawa metabolit sekunder seperti flavonoid, polifenol, tanin, dan alkaloid. Penelitian pendahuluan menyatakan bahwa fraksi tak larut etil asetat ekstrak etanolik daun kopi robusta mengandung senyawa flavonoid yang memiliki aktivitas antioksidan sangat kuat. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri fraksi tak larut etil asetat daun kopi robusta (Coffea canephora Peirre ex Froehner) terhadap bakteri Staphylococcus epidermidis. Pembuatan ekstrak etanolik daun kopi robusta (Coffea canephora Peirre ex Froehner) menggunakan metode sokletasi dengan pelarut etanol 70% pada suhu 78oC, kemudian dilakukan fraksinasi cair-cair dengan pelarut etil asetat. Hasil fraksi pekat dilakukan analisis kuantitatif flavonoid dengan metode spektrofotometri. Uji aktivitas antibakteri dilakukan dengan metode disk diffusion untuk melihat diameter zona hambat. Hasil penelitian ...
In the recent years there has been a gradually increasing demand for weight loss supplements. However, amidst wanting the perfect drop dead gorgeous body and washboard abs, people nowadays are very cautious about the side effects these supplements might have. Green coffee bean extract is an elixir for those seeking not just weight loss but add on health benefits too! One of the worlds most popular weight loss supplements, Green coffee bean extract is obtained from green coffee beans (unroasted coffee bean) that are found in a bright red coloured berry. The main bioactive component of this miraculous extract is Chlorogenic acid which has shown to have blood sugar lowering properties! A study published in American Chemical Society assessed the effect of administration of 400 mg of green coffee bean extract for 22 weeks and found • 32% reduction of the blood sugar spike post meal • 22% reduction in body weight Chlorogenic acid works in reducing weight and blood glucose by: • Delaying ...
100% pure Green Coffee Bean Extract for weight loss powder is standardized to 30% chlorogenic acids. Zero gluten, vegan, and artificial ingredients free.
Best Price Nutrition sells Green Coffee Bean Extract in a pure formula. As seen on TV with Dr. Oz. No additives. 45% Chlorogenic Acid.
The green coffee extract, rich in caffeine, triggers lipolysis in adipocytes and stimulates microcirculation. The chlorogenic acid acts as an antioxidant,
Pregnant and breast-feeding moms are not advised to take green coffee in any form or supplement, as it is not fully proven to be safe. Those who are experiencing a high level of homocysteine should shy away, as a large amount of chlorogenic acid increases plasma levels and risk heart-related conditions. People who have anxiety and bleeding disorders should not consume it, as green coffee beans can make it worse. The amount of caffeine in coffee beans are significant enough that diabetic patients may want to avoid consuming it as well. Those who are suffering from diarrhea should stay away, as the caffeine content may make it even worse. Glaucoma patients would also want to avoid caffeine, as it increases pressure in the eyes. People diagnosed with osteoporosis should not take green coffee beans as it can increase the volume of calcium that is flushed when urinating ...
trained using ordering tests for basic tastes and triangular discriminative tests. Triangular test was used in the trainingfor bitterness perception. Training was done using the shows the content of caffeic acid, catechin, extract of mate beverage fortified with 0.0025%, 0.005% chlorogenic acid, caffeine, and gallic acid in erva-mate sam- and 0.01% caffeine. The extract was prepared by mixing ples from the south of Brazil. ANOVA revealed significant erva-mate sample with 70 °C water (1:50, w/v) for 3 min effects of the regions and the cultural practices on the levels (). The beverage was put into thermo flasks of chemical compounds in erva-mate extracts. Catechin to keep temperature at 60 °C. Thirty-two candidates were was the compound found at the highest level in the infusion recruited, but due to personal schedule limits, only 20 peo- of Ilex paraguariensis (Caffeic acid and caffeine ple participated in the sensory training program, and 15 concentrations of erva-mate samples from ...
Monomeric phenolic acids, potent effectors of trichothecene biosynthesis.. Concentrated in the outer coats of grains, phenolic acids in a monomeric form are also present at the initiation of toxin production by Fusarium, and some of them (particularly ferulic acid) at high concentrations. Studies performed by the MycSA Unit have demonstrated that ferulic, p-coumaric, caffeic, sinapic and chlorogenic acids very efficiently inhibited the production of trichothecenes at concentrations similar to those present in cereals. This inhibition appeared to be closely correlated to the antioxidant potential of these compounds. Phenolic acids thus blocked toxin synthesis by reducing the expression of the principal genes coding for enzymes in the biosynthetic pathways. Individually, phenolic acids act as anti-toxin compounds. The efficacy of mixtures of phenolic acids, as they are found in grains, is currently being assessed by the MycSA Unit ...
3. Lemon balm is a good source of antioxidants. Water extracts of lemon balm contain phenolic compounds such as hydroxycinnamic acids, rosmarinic acid, chlorogenic acid, ferulic acid and caffeic acids as well as flavonoids (7). Some flavonoids that have been identified in lemon balm include luteolin, luteolin 7-O-beta-D-glucopyranoside, apigenin 7-O-beta-D-glucopyranoside, luteolin 7-O-beta-D-glucuronopyranoside, luteolin 3-O-beta-D-glucuronopyranoside and luteolin 7-O-beta-D-glucopyranoside-3-O-beta-D-glucuronopyranoside (8). The internal benefits of antioxidants and flavonoids on the body are well established and so wont be discussed here, but their benefits to the skin are less well known. Flavonoids have the ability to absorb UV light and so can play a role in protecting the skin against UV damage. One study found that extracts from Melissa were able to decrease the amount of lipid oxidation caused by UV irradiation (9). This is especially important due to the high lipid content of skin ...
A beloved beverage throughout the USA and the world at large, coffee is often blamed for various health woes. While coffee is not appropriate for everyone, and there is such a thing as too much for even the most tolerant of sippers, research has shown a vast array of health benefits.. The abundant phytochemicals found in coffee beans are responsible for the various benefits, including potential prevention of diseases such as Diabetes mellitus type II, Alzheimers disease and even cancer. Of course, we cannot overlook the well-loved stimulant effect of coffee that reliably provides us with increased stamina during exercise, and temporarily improves our cognitive function. Moreover, coffee simply makes mornings tastier.. Following is a brief overview discussing a few of the benefits to coffee consumption. These are presented in defense of coffee and as a thank you to its many active phytochemicals, including caffeine, caffeic acid, hydroxyhydroquine, chlorogenic acid, cafestol and ...
Coffee does have high concentrations of antioxidants, chlorogenic acids, and phenolic nutrients so its not all bad. Coffee in general is healthy but it does contain caffeine which needs to be limited.. You can get all of the health benefits from other foods and drinks that you get from coffee so its best not to rely on coffee for health benefits because of caffeine. Caffeine can become very addictive and can lead to very bad headaches and other side effects later down the road.. Heres how to keep the few cups of coffee per week healthier…. 1. Avoid refined sugars and artificial sweeteners. I highly recommend drinking your coffee black, but if you MUST have a sweeter cup of coffee I highly recommend pure maple syrup BUT only a very small amount. You wont need much. You can also try some other alternatives to normal table sugar like coconut sugar.. Again, you should just drink it black as this is the healthiest version of coffee.. You dont need to stop at a fancy coffee shop to get your ...
Results. Coffee appears to induce autophagy, meaning that it upregulates the activity. This can prevent the accumulation of damaged protein and cellular components, optimizing function.. Two components of coffee, chlorogenic acid and caffeic acid appear to increase skeletal muscle glucose transport into the cell. It also increases sensitivity to insulin.. Finally, coffee intake attenuates the loss of muscle mass and strength that occurs with age. It also appears to increase the regenerative capacity of skeletal muscle in the aging adult.. Conclusions. Coffee appears to have multiple beneficial effects on skeletal muscle.. Regarding autophagy, coffee appears to help the body sweep up the damaged cellular products which can improve overall cellular activity.. It improves insulin sensitivity and glucose uptake, important not only for physical activity but for disease prevention.. Finally, it blunts the age-related skeletal muscle loss effects that occur naturally, known as sarcopenia, and may ...
While Jatropha aethiopica, popularly known in Cuba as mata diabetes, is used in salads and as a dietary supplement, its chemical composition and antidiabetic properties yet remains unclear. In this work, we evaluate the qualitative and quantitative composition of ethanolic extract (EE) and phenolic fraction (PF) of Jatropha aethiopica, leaves and their hypoglycemic and hypolipidemic activity. Chemical fractionation of the ethanolic extract yielded nine compounds, which included protocatechuic acid (1), chlorogenic acid (2), caffeic acid (3), quercetin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranolsyl-(1→6)]-β-D-galactopyranoside (4), a new kaempferol 3-O-α-L-rhamnopyranosyl-(1→4)-[α-L-rhamnopyranolsyl-(1→6)]-β-D-galactopyranoside (5), kaempferol 3-O-α-L-rhamnopyranosyl-(1→2[α-L-rhamnopyranolsyl-(1→6)]-β-D-glucopyranoside (6), rutin (7), kaempferol 3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (8) and quercetin (9 ...
Mmm, coffee... almost everybody drinks it... some people have 3-4 cups per day or more. But most people dont think of it as a health drink. And its certainly NOT healthy the way most people make it with loads of added sugar or artificial sweeteners and artificial creamers. But Ill give you my tips here on how I make a healthier cup of coffee and what to watch out for... First, you may have seen debate in the past about how coffee has some compounds in it that could have negative health effects such as small amounts of acrylamides or other possibly harmful compounds in brewed coffee. But, the good news is that coffee has such high concentrations of beneficial antioxidants, phenolic nutrients, chlorogenic acids, and other healthy compounds , that it more than counteracts any bad compounds. In fact, coffee provides the biggest source of antioxidants for most Americans... although that mostly has to do with the fact that many Americans dont get enough antioxidants from fruits and veggies, so ...
Described here is a novel spectrophotometric method for estimating antioxidant capacity in a 96-well microplate using as UV probes the conjugated triene triacylglycerols (TAGs) naturally present in tung oil. The TAGs of this commercially available oil contain around 86% eleostearic acid, an octadecatrienoic acid with conjugated trienes exhibiting strong UV absorption at 273 nm. In an oil-in-water emulsion at 37 _C, the azo initiator 2,20-azobis(2-amidinopropane) dihydrochloride generated a constant flux of peroxy radicals, which destroyed the conjugated trienes. The absorbance decay at 273 nm, related to oxidative degradation of conjugated triene TAGs, was monitored in the absence and presence of various concentrations of antioxidants. To validate this new method, the antioxidant capacity of four phenolic compounds (gallic acid, (-)-epicatechin, chlorogenic acid, and rosmarinic acid) was measured using an area-under-the-curve calculation and expressed as Trolox equivalents, the value for Trolox ...
Phenolic compounds were extracted from the fruits of Morus nigra and Morus alba using methanol and acetone. The sugar-free extracts (SFEs) were prepared using Amberlite XAD-16 column chromatography. All of the SFEs exhibited antioxidant potential as determined by ABTS (0.75-1.25 mmol Trolox/g), DPPH (2,2-diphenyl-1-picrylhydrazyl) (EC50 from 48 μg/mL to 79 μg/mL), and reducing power assays. However, a stronger activity was noted for the SFEs obtained from Morus nigra fruits. These extracts also possessed the highest contents of total phenolics: 164 mg/g (methanolic SFE) and 173 mg/g (acetonic SFE). The presence of phenolic acids and flavonoids in the extracts was confirmed using HPLC method and chlorogenic acid and rutin were found as the dominant phenolic constituents in the SFEs.
Actions The Latin name for sage: salvia, means to heal. Although the effectiveness of Common Sage is often open to debate, it has been recommended at one time or another for virtually every ailment. Modern evidence supports its effects as an antihydrotic, antibiotic, antifungal, astringent, antispasmodic, estrogenic, hypoglycemic, and tonic.[1]. In a double blind, randomized and placebo-controlled trial, sage was found to be effective in the management of mild to moderate Alzheimers disease.[1] Active Constituents The strongest active constituents of Sage are within its essential oil, which contains cineole, borneol, and thujone. Sage leaf contains tannic acid, oleic acid, ursonic acid, ursolic acid, cornsole, cornsolic acid, fumaric acid, chlorogenic acid, caffeic acid, niacin, nicotinamide, flavones, flavone glycosides, and estrogenic substances.[2] Uses Internally for indigestion, gas, liver complaints, excessive lactation, excessive perspiration, excessive salivation, anxiety, depression, ...
TechnoRoasting also eliminates all of the bitterness in coffee so that it can be consumed black, without the use of creamers or sweeteners. Therefore, fats, calories and cholesterol can be eliminated from the diet.. HealthSMART coffee is the most potent, bio-available nutritional coffee…ever! Each brewed mug delivers between 4.3% and 22% of the DV (Daily Value) for 12 vitamins and minerals making it healthier than any other coffee. HealthSMART coffee also contains more antioxidants than any other coffee and Management expects it will eventually become known as the richest source of antioxidants in the diet.. The TechnoRoasting process also gives birth to other compounds that are even better for your health and HealthSMART coffee contains hundreds of micro-nutrients and minerals. We know that HealthSMART coffee contains high concentrations of Chlorogenic Acid and Glycemic Acid and numerous other antioxidants. We havent even begun to test for all of the beneficial constituents of HealthSMART ...
One cup of fresh blueberries contains 84 calories, 0 grams of cholesterol, 1.1 grams of protein, 0.49 grams of fat, 21 grams of carbohydrate and 3.6 grams of dietary fiber (14% of daily requirements).. That same one-cup serving provides 24% of daily vitamin C, 5% vitamin of B6 and 36% of vitamin K needs. Blueberries also provide iron, calcium, potassium, magnesium, phosphorus, sodium, manganese, zinc, copper, folate, beta-carotene, folate, choline, vitamin A and vitamin E.. In addition to anthocyanins, blueberries contain a diverse range of phenolic compounds such as quercetin, kaempferol, myricetin and chlorogenic acid - all of which contribute to their antioxidant capacity.5. Due to these large amounts of bioactive compounds, blueberries rank very highly on the Aggregate Nutrient Density Index (ANDI), which rates foods based on their vitamin and mineral content, phytochemical composition and antioxidant capacity. Foods that have the most nutrients per calorie have the highest rankings, and ...
Mate contains several vitamins and minerals important to human health, including vitamins A, B1, B2, C, and E, as well as phosphorus, iron, calcium. It contains significant levels of polyphenol antioxidants, and has a slightly higher antioxidant capacity than green tea. In 2011, research at the University of Illinois found yerba mate to inhibit the proliferation of colon and oral cancer cells. On average, mate tea contains 92 mg of the antioxidant chlorogenic acid per gram of dry leaves, and no catechins, giving it a significantly different antioxidant profile to other teas.. ...
DR2B and DR2C extracts, from peel of commercially and physiologically ripe eggplants, were studied for the antioxidative cytoprotective properties and anti-HSV-1 activity, in line with the evidence that several antioxidants can impair viral replication by maintaining reducing conditions into the host cells. The antioxidative cytoprotective effects against tBOOH-induced damage was assessed in Caco2 cells, while the antiviral activity was studied in Vero cells; phenolic and anthocyanin fingerprint was characterized by integrated phytochemical methods. Results highlighted different compositions of the extracts, with chlorogenic acid and delphinidin-3-rutinoside as the major constituents; other peculiar phytochemicals were also identified. DR2C resulted able to partly counteract the tBOOH-induced cytotoxicity, with a remarkable lowering of lactate metabolism under both normoxia and hypoxia. DR2B and DR2C reduced ROS production, possessed scavenging and chelating properties. Interestingly, DR2C increased
Free Radicals and Heart Disease. Free radicals are unbalanced molecules (short of an electron) that attempt to achieve balance by stealing electrons from other molecules (your cells). This causes oxidation (same as rust) to cells of the body causing the cells to be damaged (less than perfect). When the lining of the arteries are damaged by free radicals in the blood, the body attempts to repair the artery with a cholesterol patch. As free radicals continue robbing electrons now from the cholesterol patches, they too become damaged and this sets the cycle of atherosclerosis.. Free radicals can be controlled with anti-oxidants. White tea contains catechins, quercetan, kaempferol, chlorogenic acid, theanine, theobromine and theophylline which are potent antioxidants and/or fight inflammation (white tea contains the least amount of flouride and aluminum found in all teas - white, green or black teas). Many vitamins fight free radicals and have other benefits for heart health. Heart healthy vitamins ...
1R,3R,5R,7S,8S,9S)-3,8-epoxy-1-O-ethyl-5-hydroxyvalechlorine, (1S,3R,5R,7S,8S,9S)-3,8-epoxy-1-O-ethyl-5-hydroxyvalechlorine, (1S,3R,5R,7S,8S,9S)-3,8-epoxy-1,5-dihydroxyvalechlorine, 2S(-)-hesperidin, (5S,6S,8S,9R)-1,3-isovaleroxy-?4,11-1,3-diol, (5S,6S,8S,9R)-3-isovaleroxy-6-isovaleroyloxy-?4, -1,3-diol, (5S,6S,8S,9R)-6-isovaleroyloxy-?4, -1,3-diol, (5S,7S,8S,9S)-7-hydroxy-8-isovaleroyloxy-?4, -dihyronepetalactone, (5S,7S,8S,9S)-7-hydroxy-10-isovaleroyloxy-?4, -dihyronepetalactone, (5S,8S,9S)-10-isovaleroyloxy-?4, -dihyronepetalactone, 6-methylapigenin, 6-O-acyl-beta-D-glucosyl-clionasterols, 14-methylpentadecanoyl, actinidine, all-heal, amantilla, Balderbrackenwurzel (German), Baldisedron , Baldrian (German), Baldrian-Dispert, Baldrianwurzel (German), baldrinal, baldrion, Belgian valerian, blessed herb, capons tail, chlorogenic acid, chlorovaltrates A-O, clionasterol-3-O-beta-D-glucopyranoside, common valerian, English valerian, Euvegal forte, flavonoids, fragrant valerian, garden heliotrope, ...
1R,3R,5R,7S,8S,9S)-3,8-epoxy-1-O-ethyl-5-hydroxyvalechlorine, (1S,3R,5R,7S,8S,9S)-3,8-epoxy-1-O-ethyl-5-hydroxyvalechlorine, (1S,3R,5R,7S,8S,9S)-3,8-epoxy-1,5-dihydroxyvalechlorine, 2S(-)-hesperidin, (5S,6S,8S,9R)-1,3-isovaleroxy-?4,11-1,3-diol, (5S,6S,8S,9R)-3-isovaleroxy-6-isovaleroyloxy-?4, -1,3-diol, (5S,6S,8S,9R)-6-isovaleroyloxy-?4, -1,3-diol, (5S,7S,8S,9S)-7-hydroxy-8-isovaleroyloxy-?4, -dihyronepetalactone, (5S,7S,8S,9S)-7-hydroxy-10-isovaleroyloxy-?4, -dihyronepetalactone, (5S,8S,9S)-10-isovaleroyloxy-?4, -dihyronepetalactone, 6-methylapigenin, 6-O-acyl-beta-D-glucosyl-clionasterols, 14-methylpentadecanoyl, actinidine, all-heal, amantilla, Balderbrackenwurzel (German), Baldisedron , Baldrian (German), Baldrian-Dispert, Baldrianwurzel (German), baldrinal, baldrion, Belgian valerian, blessed herb, capons tail, chlorogenic acid, chlorovaltrates A-O, clionasterol-3-O-beta-D-glucopyranoside, common valerian, English valerian, Euvegal forte, flavonoids, fragrant valerian, garden heliotrope, ...
Honeysuckle Extract is extracted from the flowers of Lonicara japonica, which contains chlorogenic acid, a phenolic natural product isolated from the le...
Teucrium, etc ; acetone; Staphylococcus aureus; rutin; methanol; minimum inhibitory concentration; phenols; anti-infective agents; plant extracts; fungi; ethyl acetate; chlorogenic acid; antifungal properties; Show all 13 Subjects ...
Eggplant has among the many phytonutrients, two very important ones - nasunin and chlorogenic acid that make it very healthy vegetable. Read on to know about the many health benefits of eggplant...
The amount of dietary trace elements absorbed from a meal depends, among other factors, on the quantities of certain minor plant constituents present in the meal. These substances can act as ligands and bind trace elements in the digestive tract in a
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
El compuesto principal responsable del efecto laxante de las ciruelas es sorbitol, ácidos neochlorogenic y ácidos chlorogenic. La cantidad en las ciruelas del sorbitol es de alrededor de 15 gramos por 100 gramos. Este compuesto (sorbitol) tiene un efecto laxante conocido y es edulcorante. Los principales azúcares que se encuentran en las ciruelas frescas son glucosa, fructosa, sacarosa y sorbitol. En el estudio de 2010 de María Stacewicz-Sapuntzakis et al. descubrió que el azúcar varía de una especie a otra; ... El contenido total de azúcar en la fruta fresca varió de 12.8 g a 29 g, con un promedio de 19.4 g / 100 g. La variabilidad individual del azúcar por 100 g fue la siguiente: el contenido de glucosa varió de 3,1 a 10,2 g (promedio de 6,1 g); fructosa de 2.5 a 5.1 (promedio de 3.4 g); y sacarosa de 2.9 a 6.2 g (4.5 g promedio) ... en porcentaje encontraron que la glucosa constituía ... 31%, fructosa 18%, sacarosa 23% y sorbitol 28% del total de azúcares ... Estas frutas ...
Methods The antitumor effect of C. crepidioides was evaluated in S-180-cell-bearing mice. Cell growth was assessed using a colorimetric assay. Nitrite and nitrate levels were measured by colorimetry. The expression levels of inducible NO synthase (iNOS) in murine RAW264.7 macrophages was assessed by reverse transcriptase-polymerase chain reaction. Activation of iNOS promoter was detected by reporter gene. Activation of nuclear factor-κB (NF-κB) was evaluated by electrophoretic mobility shift assay. The role of NF-κB signaling was analyzed using inhibitors of NF-κB and dominant-negative mutants, and Western blot analysis ...
Nonvolatile chlorogenic acids[edit]. Chlorogenic acids belong to a group of compounds known as phenolic acids, which are ... Chlorogenic acids are homologous compounds comprising caffeic acid, ferulic acid and 3,4-dimethoxycinnamic acid, which are ... The lipids found in green coffee include: linoleic acid, palmitic acid, oleic acid, stearic acid, arachidic acid, diterpenes, ... hexanoic acid (fatty-rancid odor), heptanoic acid (fatty odor), octanoic acid (repulsive oily rancid odor); nonanoic acid (mild ...
Niggeweg R, Michael AJ, Martin C (June 2004). "Engineering plants with increased levels of the antioxidant chlorogenic acid". ... PPO-silenced apples are unable to convert chlorogenic acid into the standard quinone product.[2] ... "Nucleic Acids Research. 33 (Web Server issue): W589-91. doi:10.1093/nar/gki419. PMC 1160180. PMID 15980542.. ... "Nucleic Acids Research. 32 (Web Server issue): W113-20. doi:10.1093/nar/gkh408. PMC 441546. PMID 15215362.. ...
Niggeweg R, Michael A, Martin C (2004). "Engineering plants with increased levels of the antioxidant chlorogenic acid". Nat ... "Nucleic Acids Res 33 (Web Server issue): W589-91. PMC 1160180. PMID 15980542. doi:10.1093/nar/gki419.. ... "Nucleic Acids Res 32 (Web Server issue): W113-20. PMC 441546. PMID 15215362. doi:10.1093/nar/gkh408.. ... "Nucleic Acids Res 32 (Web Server issue): W124-9. PMC 441580. PMID 15215364. doi:10.1093/nar/gkh442.. ...
Amino acids • Bodybuilding supplement • Energy drink • Energy bar • Fatty acids • Herbal Supplements • Minerals • Prebiotics • ... Folic acid (B9) • Cyanocobalamin (B12) • Ascorbic acid (ജീവകം സി) • Ergocalciferol and Cholecalciferol (ജീവകം ഡി) • Tocopherol ... Retinol (ജീവകം എ) • B vitamins: തയാമിൻ (B1) • Riboflavin (B2) • Niacin (B3) • Pantothenic acid (B5) • Pyridoxine (B6) • Biotin ... Lipoic acid • Milk thistle • Melatonin • Red yeast rice • Royal jelly • Saw palmetto • സ്പൈറുലിന • St John's wort • Taurine • ...
Bandyopadhyay, G (2004). "Chlorogenic acid inhibits Bcr-Abl tyrosine kinase and triggers p38 mitogen-activated protein kinase- ...
The shoots of Calluna vulgaris contain the phenolic compounds chlorogenic acid, its 3-O-glucoside, 3-O-galactoside and 3-O- ... but has defeated many a gardener on less acid soil.[7] There are many named cultivars, selected for variation in flower colour ...
... isobutyric acid, nicotinic acid, ascorbic acid, riboflavin, choline, pyridoxine, triterpenes, chlorogenic acid and sugars among ...
It has been shown that this is in part due to its high concentrations of phenolic compounds such as chlorogenic acid and ... caffeic acid which allow it to negate the destructive capacity of the reactive oxygen species generated by the drying process; ...
... chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate". ... Caffeic acid phenethyl ester (CAPE) is a natural phenolic chemical compound. It is the ester of caffeic acid and phenethyl ... Natarajan K, Singh S, Burke TR, Grunberger D, Aggarwal BB (August 1996). "Caffeic acid phenethyl ester is a potent and specific ... Orban Z, Mitsiades N, Burke TR, Tsokos M, Chrousos GP (2000). "Caffeic acid phenethyl ester induces leukocyte apoptosis, ...
Caffeic acid is also a digestive break-down product of chlorogenic acid, high in coffee and some fruits and vegetables.[37] ... Bacteria metabolize chenodeoxycholic acid into the secondary bile acid lithocholic acid, and they metabolize cholic acid into ... There are additional secondary bile acids, such as ursodeoxycholic acid. Deoxycholic acid is soluble in alcohol and acetic acid ... 12α-dihydroxy-5β-cholan-24-oic acid, is a bile acid. Deoxycholic acid is one of the secondary bile acids, which are metabolic ...
Niggeweg R, Michael A, Martin C (2004). "Engineering plants with increased levels of the antioxidant chlorogenic acid". Nat ... "Nucleic Acids Res. 33 (Web Server issue): W589-91. doi:10.1093/nar/gki419. PMC 1160180 . PMID 15980542.. CS1 maint: Multiple ... "Nucleic Acids Res. 32 (Web Server issue): W113-20. doi:10.1093/nar/gkh408. PMC 441546 . PMID 15215362.. CS1 maint: Multiple ... "Nucleic Acids Res. 32 (Web Server issue): W124-9. doi:10.1093/nar/gkh442. PMC 441580 . PMID 15215364.. CS1 maint: Multiple ...
Most NONOates are stable in alkaline solution above pH 8.0 (e. g. 10 mM NaOH) and can be stored at −20 °C in this way for the short term. To generate NO from NONOates, the pH is lowered accordingly. Typically, a dilution of the stock NONOate solution is made in a phosphate buffer (pH 7.4; tris buffers can also be used) and incubated at room temperature for the desired time to allow NO to accumulate in solution. This is often visible as bubbles at high NONOate concentrations. Incubation time is important, since the different NONOates have different half-lives (t½) in phosphate buffer at pH 7.4. For example, the half-life of MAHMA NONOate under these conditions is ~3.5 minutes, whilst the t½ of DPTA NONOate is 300 minutes. This is often useful in biological systems, where a combination of different NONOates can be used to give a sustained release of nitric oxide. At pH 5.0, most NONOates are considered to decompose almost instantaneously. ...
... are also used in the formation of oximes with the stronger carbon acids and acid or base catalysis for example ... Organic nitrites are prepared from alcohols and sodium nitrite in sulfuric acid solution. They decompose slowly on standing, ... Formally they are alkyl esters of nitrous acid. They are distinct from nitro compounds (R-NO2). ... in the reaction of 2-butanone, ethyl nitrite and hydrochloric acid forming the oxime,[7] the similar reaction with phenacyl ...
... , or 7-NI, is a heterocyclic small molecule containing an indazole ring that has been nitrated at the 7 position. Nitroindazole acts as a selective inhibitor for neuronal nitric oxide synthase, a hemoprotein enzyme that, in neuronal tissue, converts arginine to citrulline and nitric oxide (NO).[1] Nitric oxide can diffuse through the plasma membrane into neighbouring cells, allowing cell signalling, so nitroindazole indirectly inhibits this signalling process.[2][3][4] Other inhibitors exist such as 3-bromo-7-nitroindazole, which is more potent but less specific,[5] or NPA (N-propyl-L-arginine), which acts on a different site.[6] ...
The following adverse effects have been reported in studies with isosorbide mononitrate: Very common: Headache predominates (up to 30%) necessitating withdrawal of 2 to 3% of patients, but the incidence reduces rapidly as treatment continues.[7] Common: Tiredness, sleep disturbances (6%) and gastrointestinal disturbances (6%) have been reported during clinical trials with isosorbide mononitrate modified-release tablets, but at a frequency no greater than for placebo. Hypotension (4 to 5%), poor appetite (2.5%), nausea (1%)[7] Adverse effects associated with the clinical use of the drug are as expected with all nitrate preparations. They occur mainly in the early stages of treatment.[7] Hypotension (4%) with symptoms such as dizziness and nausea (1%) have been reported. In general, these symptoms disappear during long-term treatment.[7] Other reactions that have been reported with isosorbide mononitrate-modified release tablets include tachycardia, vomiting, diarrhoea, vertigo, and heartburn.[7] ...
... (ISDN) is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart.[1] It has been found to be particularly useful in heart failure due to systolic dysfunction together with hydralazine.[2][1] It is taken by mouth or under the tongue.[1] Common side effects include headache, lightheadedness with standing, and blurred vision.[1] Severe side effects include low blood pressure.[1] It is unclear if use in pregnancy is safe for the baby.[1] It should not be used together with medications within the sildenafil family.[1] ISDN is in the nitrate family of medications and works by dilating blood vessels.[1] Isosorbide dinitrate was first written about in 1939.[3] It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[4] ISDN is available as a generic medication.[1] A long-acting form exists.[1] ...
The main Polyphenols contained in the tobacco leaf are rutin and chlorogenic acid. Amino acids contained include glutamic acids ... E.A.H. Roberts The polyphenols and amino acids of tobacco leaf, Archives of Biochemistry and Biophysics, Volume 33, Issue 2, ... asparagine, glutamine, and γ-Aminobutyric acid [5] Pyridine alkaloids are present in tobacco as free bases and salts. Nicotine ... propionic acid, anthalin, anethole, acrolein, cembrene, choline, nicotelline, nicotianine, and pyrene.[8] ...
... and chlorogenic acid. Dandelion also contains terpenoids, triterpenes, and sesquiterpenes. Dandelion has been used as an herbal ... Dandelion contains flavonoids including luteolin, apigenin, isoquercitrin (a quercetin-like compound), caffeic acid, ...
... mainly as neochlorogenic acids and chlorogenic acids) and sorbitol.[4] ...
They produce iso/chlorogenic acid, sesquiterpene lactones, pentacyclic triterpene alcohols, various alkaloids, acetylenes ( ...
Some examples of these antagonists are caffeic acid, chlorogenic acid, and tannic acid. These compounds interact with the ... Thiamine and its acid metabolites (2-methyl-4-amino-5-pyrimidine carboxylic acid, 4-methyl-thiazole-5-acetic acid, and thiamine ... PDH links glycolysis to the citric acid cycle, while the reaction catalyzed by OGDH is a rate-limiting step in the citric acid ... "Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and ...
The major identified compounds include neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, caffeoylshikimic acid and ... Pau, L. T.; Salmah, Y.; Suhaila, M. (2002). "Antioxidative properties of roselle (Hibiscus sabdariffa L.) in linoleic acid ... as well as protocatechuic acid. The dried calyces contain the flavonoids gossypetin, hibiscetine and sabdaretine. The major ...
... chlorogenic acid.[38]. Allergies[edit]. Case reports of itchy skin or mouth, mild headache, and stomach upset after handling or ...
"Chlorogenic acid" kan hore wuxuu hoos u dhigaa dhiig karka, kan dambane wuxuu hoos u dhigaa sokorta khaasatan markii wax la ...
... such as gallic acid, chlorogenic acid, syringic acid, (+)-catechin, (−)-epicatechin and rutin.[37][38] Fig color may vary ... Veberic R, Colaric M, Stampar F (2008). "Phenolic acids and flavonoids of fig fruit (Ficus carica L.) in the northern ...
Lysergic acid 2-butyl amide • Lysergic acid 3-pentyl amide • Methysergide; Phenethylamines: 25I-NBF • 25I-NBMD • 25I-NBOH • 25I ... Agonists: Lysergamides: ALD-52 • Ergometrine • Lisuride • Lysergic acid 2,4-dimethylazetidide • ال‌اس‌دی • LSD-Pip • ... Tryptophan or (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... Cichoric acid. *سینامیک اسید. *Chlorogenic acid. *Diferulic ...
... chlorogenic, vanillic, caffeic, p-coumaric and salicylic acid, cinnamic acid and hydroxybenzaldehydes such as p- ... Phenolic acids, Phenolic aldehydes Gallic, salicylic acids 8 C6-C2 1 Acetophenones, Tyrosine derivatives, Phenylacetic acids 3- ... Homogentisic acid 9 C6-C3 1 Hydroxycinnamic acids, Phenylpropenes, Coumarins, Isocoumarins, Chromones Caffeic, ferulic acids, ... Phenolic acids can be found in mushroom basidiomycetes species.[46] For example, protocatechuic acid and pyrocatechol are found ...
... chlorogenic, vanillic, caffeic, p-coumaric and salicylic acid, cinnamic acid and hydroxybenzaldehydes such as p- ... 3-Acetyl-6-methoxybenzaldehyde, Tyrosol, p-Hydroxyphenylacetic acid, Homogentisic acid. 9. C6-C3. 1. Hydroxycinnamic acids, ... Phenolic acids, Phenolic aldehydes. Gallic, salicylic acids. 8. C6-C2. 1. Acetophenones, Tyrosine derivatives, Phenylacetic ... Phenolic acids can be found in mushroom basidiomycetes species.[59] For example, protocatechuic acid and pyrocatechol are found ...
α-Cyano-4-hydroxycinnamic acid. *Caffeic acid. *Chicoric acid. *Cinnamic acid. *Chlorogenic acid ... Dihydroxybenzoic acids. *2,3-Dihydroxybenzoic acid (Hypogallic acid). *2,4-Dihydroxybenzoic acid ...
α-Cyano-4-hydroxycinnamic acid. *Caffeic acid. *Cichoric acid. *Cinnamic acid. *Chlorogenic acid ... Short-chain fatty acids[edit]. When fermentable fiber is fermented, short-chain fatty acids (SCFA) are produced. SCFAs are ... Almost all of these short-chain fatty acids will be absorbed from the colon. This means that fecal short-chain fatty acid ... The production of short-chain fatty acids has several possible actions on the gut mucosa. All of the short-chain fatty acids ...
... syringic acid, vanillin, ferulic acid, sinapic acid, coumaric acid, chlorogenic acid, epicatechin, and arbutin.[49][50] ... The pineapple carries out CAM photosynthesis,[13] fixing carbon dioxide at night and storing it as the acid malate, then ... "Smooth cayenne", a 2.5- to 3.0-kg (5- to 6-lb), pale yellow- to yellow-fleshed, cylindrical fruit with high sugar and acid ... Pineapple fruits and peels contain diverse phytochemicals, among which are polyphenols, including gallic acid, ...
α-Cyano-4-hydroxycinnamic acid. *Caffeic acid. *Cichoric acid. *Cinnamic acid. *Chlorogenic acid ... The gallic acid dimer, ellagic acid (M.W. 302, right), a molecule at the core of naturally occurring phenolic compounds of ... The raspberry ellagitannin (M.W. ~2450),[9] on the other hand, with its 14 gallic acid moieties (most in ellagic acid-type ... Plant-derived polyphenol, tannic acid, formed by esterification of ten equivalents of the phenylpropanoid-derived gallic acid ...
The shoots of Calluna vulgaris contain the phenolic compounds chlorogenic acid, its 3-O-glucoside, 3-O-galactoside and 3-O- ... but has defeated many a gardener on less acid soil.[7] There are many named cultivars, selected for variation in flower colour ...
Sage leaf contains tannic acid, oleic acid, ursolic acid, carnosol, carnosic acid, fumaric acid, chlorogenic acid, caffeic acid ... "Absinthe and gamma-aminobutyric acid receptors". Proceedings of the National Academy of Sciences of the United States of ...
Recently, cichoric acid (CHA) and chlorogenic acid (CGA) were predicted by docking methods to be allosteric inhibitors that ... Characterization of Protein Tyrosine Phosphatase 1B Inhibition by Chlorogenic Acid and Cichoric Acid.. Lipchock JM1, ... Characterization of Protein Tyrosine Phosphatase 1B Inhibition by Chlorogenic Acid and Cichoric Acid ... Characterization of Protein Tyrosine Phosphatase 1B Inhibition by Chlorogenic Acid and Cichoric Acid ...
Select 2017 high quality Chlorogenic Acid Factory products in best price from certified Chinese Malic Acid manufacturers, ... Eucommia Chlorogenic Acid suppliers, wholesalers and factory on Made-in-China.com ... Related Searches: Kojic Acid Malic Acid Eucommia Chlorogenic Acid Phosphorous Acid Citric Acid Monohydrate Arachidonic Acid ... Oxidizing Acid (1) Non Oxidizing Acid (1) Volatility Volatile Acid (1) Stability Stabilized Acid (1) ...
Chlorogenic acid. Description. Chlorogenic acid is an ester of caffeic acid and quinic acid. Chlorogenic acid is the major ... Coffee is a complex mixture of chemicals that provides significant amounts of chlorogenic acid. The chlorogenic acid content of ... Kang J, Liu Y, Xie MX, Li S, Jiang M, Wang YD: Interactions of human serum albumin with chlorogenic acid and ferulic acid. ... Lafay S, Morand C, Manach C, Besson C, Scalbert A: Absorption and metabolism of caffeic acid and chlorogenic acid in the small ...
... the main phenolic acid in the human diet, and of caffeic acid were studied in rats in order to determine whether chlorogenic ... The absorption and metabolism in the small intestine of chlorogenic acid (5-O-caffeoylquinic acid), ... 0/Antioxidants; 0/Caffeic Acids; 0/Coumaric Acids; 0/Hydroxybenzoic Acids; 29656-58-4/phenolic acid; 327-97-9/Chlorogenic Acid ... Chlorogenic Acid / metabolism*, pharmacokinetics. Coumaric Acids / administration & dosage. Hydrolysis. Hydroxybenzoic Acids / ...
Effects of non-covalent interactions with 5-O-caffeoylquinic acid (chlorogenic acid) on the heat denaturation and solubility of ... The non-covalent interactions between the monomeric phenolic compound chlorogenic acid (5-CQA) and bovine serum albumin (BSA), ... chlorogenic acid · globular protein · lysozyme · acidity · alkalinity · article · covalent bond · enthalpy · food · high ... Chlorogenic Acid · Drug Interactions · Heat · Hydrogen-Ion Concentration · Lactalbumin · Muramidase · Osmolar Concentration · ...
To investigate the mechanism of the combined effects of chlorogenic acid (CGA) and caffeine on lipid metabolism in high-fat ... Collaborative effects of chlorogenic acid and caffeine on lipid metabolism via the AMPKα-LXRα/SREBP-1c pathway in high-fat diet ... Collaborative effects of chlorogenic acid and caffeine on lipid metabolism via the AMPKα-LXRα/SREBP-1c pathway in high-fat diet ... To investigate the mechanism of the combined effects of chlorogenic acid (CGA) and caffeine on lipid metabolism in high-fat ...
PALABRAS CLAVE: antimicrobial, antioxidant, Auricularia delicata, chlorogenic acid, hepatoprotective, medicinal mushrooms. ... Its protective property might be due to the presence of a mitochondrial-targeted antioxidant effect of chlorogenic acid. The ... Phytochemical analysis using high-performance liquid chromatography revealed the presence of chlorogenic acid in the extracts. ...
A review of chlorogenic acid and genistein states:. Apples contain small amounts of chlorogenic acid. It is somewhat ... Will chlorogenic acid displace Olmesartan from VDR, when Olmesartan Ki=10 nanomols and Chlorogenic Acid Ki = 8 nanomols ?. ... So, if we will consume chlorogenic acid, wont we lose benicar protective blockade due to chlorogenic acid - benicar ... I am supposing its the chlorogenic acid. Probably not so much preventing it as postponing it, I guess!. ...
... chlorogenic acid (CGA) and p-coumaroyl quinate. Real time PCR experiments demonstrated an increase in the expression level of ... coli showed that this enzyme can catalyze the esterification of quinic acid with caffeoyl-CoA or p-coumaroyl-CoA to generate, ... which mainly result from their high content of polyphenolic compounds such as monocaffeoylquinic and dicaffeoylquinic acid (DCQ ... HQT in UV-C treated leaves, and established a correlation between the synthesis of phenolic acids and protection against damage ...
Addition of the G6PT inhibitor chlorogenic acid to primary hepatocytes suppressed H6PDH production.. CONCLUSIONS/INTERPRETATION ...
... has functional parent trans-caffeic acid (CHEBI:16433) chlorogenic acid (CHEBI:16112) has role ... chlorogenic acid (CHEBI:16112) is a tannin (CHEBI:26848) chlorogenic acid (CHEBI:16112) is conjugate acid of chlorogenate ( ... chlorogenic acid (CHEBI:16112) has role plant metabolite (CHEBI:76924) chlorogenic acid (CHEBI:16112) is a cinnamate ester ( ... chlorogenic acid (CHEBI:16112) has functional parent (−)-quinic acid (CHEBI:17521) ...
To help me with this is been taking Chlorogenic Acid supplements. It seems to be helping. I did some studies on myself, and ... To help me with this is been taking Chlorogenic Acid supplements. It seems to be helping. I did some studies on myself, and ... http://www.lef.org/Vitamins-Supplements/Item01620/CoffeeGenic-Green-Coffee-Extract.html?source=search&key=chlorogenic%20acid ...
Chlorogenic acids - compounds found in coffee - may improve measures like cognitive performance and motor speeds, says a new ... Japanese researchers extracted Chlorogenic acids from green coffee beans. Image © Getty Images / Fydorov. Related tags: ... "Effect of Chlorogenic Acids on Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Trial"​. Authors: K. Saitou ... Chlorogenic acids - compounds found in coffee - may improve measures like cognitive performance and motor speeds, says a new ...
Bioavailability of Chlorogenic and Phenolic Acids From Soluble Coffees. The safety and scientific validity of this study is the ... Composite of pharmacokinetics: AUC, Sum of AUC, Cmax, Tmax and T1/2 of plasma chlorogenic and phenolic acids from the other ... Composite of pharmacokinetics: sum of AUC of chlorogenic and phenolic acids the of extreme treatments. [ Time Frame: 18 months ... of this clinical trial is to investigate the possible difference in the bioavailability of chlorogenic and phenolic acids from ...
Both the chlorogenic acids and the flavan-3-ols are absorbed in the small intestine and appear in the circulatory system ... Recent evidence indicates that some colon-derived phenolic acids have in vitro anti-inflammatory activity. ... This paper reviews recent human studies on the bioavailability of chlorogenic acids in coffee and green tea flavan-3-ols in ... Keywords: coffee; green tea; chlorogenic acids; flavan-3-ols; human bioavailability coffee; green tea; chlorogenic acids; ...
where to buy 327-97-9(Chlorogenic acid).Also offer free database of 327-97-9(Chlorogenic acid) including MSDS sheet(poisoning, ... Chlorogenic acid (8CI);Eucommia Leaf Extract;Chlorogenate;5-O-(3,4-Dihydroxycinnamoyl)-L-quinic acid;Chlorogenic acid 98% (UV); ... Chinese Natural Herbal Health Care Medicine of Chlorogenic Acid;3-O-Caffeoylquinic acid;HoneySuchle Flower Extract; ... 1. High quality 1.1 We can provide high purity Chlorogenic acid (90%, 98%) via of refining process with resin separation; 1.2 ...
... Tian Yi Kang,1 ... A. L. Zhang, Q. Ma, and J. M. Gao, "Studies on bioactivities of chlorogenic acid and its analogues," Chinese Traditional and ... H. Kasai, S. Fukada, Z. Yamaizumi et al., "Action of chlorogenic acid in vegetables and fruits as an inhibitor of 8-hydroxy- ... H. Z. Wu, J. Luo, Y. X. Yin et al., "Effects of chlorogenic acid, an active compound activating calcineurin, purified from Flos ...
... chlorogenic acid, chlorogenic acid methyl ester, 1,5-dicaffeoyl quinic acid, 3,5-dicaffeoyl quinic acid, methylester of 3,5- ... Chlorogenic acid an ester of caffeic acid and quinic acid (3-O-caffeoylquinic acid (CGA)) possess significant antioxidant ... due to their chlorogenic acid contents. Derivatives of chlorogenic acid 3,4 and 3,5 dicaffeoylquinic acids were also reported ... activities due to their high content of chlorogenic acid as well as caffeoylquinic acid derivatives. Chlorogenic acid and ...
Chlorogenic acid also decreased malondialdehyde levels in the hippocampus and frontal cortex. In vitro, chlorogenic acid was ... chlorogenic acid increased the latency time in the target quadrant in a dose-dependent manner. Ex vivo, chlorogenic acid ... The chlorogenic acid significantly improved the impairment of short-term or working memory induced by scopolamine in the Y-maze ... Chlorogenic acid is a major polyphenolic component of many plants and beverages, and is particularly abundant in coffee. We ...
Chlorogenic Acid by DesBio promotes optimal overall health and helps relieve congestion, fever and other symptoms. Place your ... Maintain Your Overall Health with Chlorogenic Acid. Chlorogenic acid is cinnamic acid derivative that is thought to provide a ... Maintain Your Overall Health with Chlorogenic Acid. Chlorogenic acid is cinnamic acid derivative that is thought to provide a ... Chlorogenic Acid. Product Approval Required: Call 1-800-673-1245 for a no-cost consultation. Already called? Login DesBio ...
The researchers identified chlorogenic acid and neochlorogenic acid as the components responsible for killing the cancer cells ... The researchers identified chlorogenic acid and neochlorogenic acid as the components responsible for killing the cancer cells. ... This research is of interest to the Potato sector since potatoes are a significant source of chlorogenic acid. In the potato, ... A closer look at the extracts determined that two specific phenolic acid components - chlorogenic and neochlorogenic - were ...
Antitumor Molecular Mechanism of Chlorogenic Acid on Inducting Genes GSK-3β and APC and Inhibiting Gene β-Catenin. Ruoshi Xu,1 ... by chlorogenic acid were discussed (CGA). Method. The different genes were scanned by the 4*44K mouse microarray chips. The ...
Several mechanisms have been suggested for effects of chlorogenic acid on glucose metabolism. In vitro, chlorogenic acid has ... Chlorogenic acids and other cinnamates: nature, occurrence and dietary burden. J Sci Food Agric 1999; 79: 362- 372. ... RESULTS Chlorogenic acid and trigonelline ingestion significantly reduced glucose (−0.7 mmol/l, P = 0.007, and −0.5 mmol/l, P ... Chlorogenic acid reduces the plasma glucose peak in the oral glucose tolerance test: effects on hepatic glucose release and ...
1) Background: Chlorogenic acids (CGAs) have been attracting interest of late, owing to their health benefits. Here, we ... Ito, H.; Sun, X.L.; Watanabe, M.; Okamoto, M.; Hatano, T. Chlorogenic acid and its metabolite m-coumaric acid evoke neurite ... 1) Background: Chlorogenic acids (CGAs) have been attracting interest of late, owing to their health benefits. Here, we ... Chlorogenic acids (CGAs) are polyphenols abundant in coffee, which have been shown to be promising in preventing ...
Green Coffee Extract contains high levels of chlorogenic acids and ideal for those following a calorie controlled weight loss ... Chlorogenic Acid. This contains high levels of chlorogenic acids and ideal for those following a calorie controlled weight loss ... Green Coffee Extract contains high levels of chlorogenic acids and ideal for those following a calorie controlled weight loss ... The extract used is decaffeinated and contains high levels of the active compounds called chlorogenic acids. Read more ...
... chlorogenic acid) the related 3-CQA (neochlorogenic acid) and 4-CQA (cryptochlorogenic acid), all of which occur in coffee are ... 4 The main phenolic components in coffee are the chlorogenic acids (CGAs) among which the caffeoylquinic acids (CQAs), 5-CQA, 3 ... Variations in caffeine and chlorogenic acid contents of coffees: what are we drinking?. Iziar A. Ludwig a, Pedro Mena b, Luca ... a Caffeine and chlorogenic acid levels expressed as mean values with standard error values ,7% of the mean in all instances (n ...
Chlorogenic acid increases muscle cells insulin sensitivity and chases glucose into these cells. ... Chlorogenic acid is a prominent component of coffee and supplements that contain Green Coffee Bean extract. The compound might ... Chlorogenic acid. Chlorogenic acid is found in much of the food we eat. In fact, its probably the phenol we consume the most ... Red wine (contains chlorogenic acid) boosts testosterone level 10.10.2012. Prunes (contain chlorogenic acid) boost IGF-1 levels ...
Thus, salinity-induced chlorogenic acid accumulation in flower buds depended on an amplification effect of growth reduction. In ... Specifically, the total concentration of leaf chlorogenic acids was increased by 145.74% and 50.34% after 30 days of 150 and ... Similarly, the concentrations of chlorogenic acids were higher in the leaves of plants in saline, compared with non-saline, ... Specifically, the total concentration of leaf chlorogenic acids was increased by 145.74% and 50.34% after 30 days of 150 and ...
Daily supplementation with 300 milligrams of chlorogenic acids - the bioactive substances in Green Coffee Bean extract - ... That could well be related to the phyochemical chlorogenic acid. Chlorogenic acid chases glucose into muscle cells. Chlorogenic ... "Consumption of high-chlorogenic acids coffee for 12 weeks by overweight adults might lower visceral fat area, total abdominal ... Coffee ingredient chlorogenic acid blocks insulins pro-aging effect. Coffee drinkers live a little longer than people who do ...
CAFFEIC ACID. 6 [hp_X] in 1 mL. CHLOROGENIC ACID (UNII: 318ADP12RI) (CHLOROGENIC ACID - UNII:318ADP12RI). CHLOROGENIC ACID. 6 [ ... Label: ALLERPHENEX I- acetaldehyde, acetylcholine chloride, adrenalinum, caffeic acid, chlorogenic acid, cinnamic acid, ... ALLERPHENEX I- acetaldehyde, acetylcholine chloride, adrenalinum, caffeic acid, chlorogenic acid, cinnamic acid, coumarinum, ... ALLERPHENEX I- acetaldehyde, acetylcholine chloride, adrenalinum, caffeic acid, chlorogenic acid, cinnamic acid, coumarinum, ...
Chlorogenic acid (CGA), an important biologically active dietary polyphenol, is produced by certain plant species and is a ... Chlorogenic acid (CGA), an important biologically active dietary polyphenol, is produced by certain plant species and is a ... The potential effects of chlorogenic acid, the main phenolic components in coffee, on health: a comprehensive review of the ... We searched PubMed, Embase, Amed and Scopus using the following search terms: ("chlorogenic acid" OR "green coffee bean extract ...
Chlorogenic acid, a natural phenolic acid present in fruits and plants, provides beneficial effects for human health. The ... Chlorogenic acid decreases intestinal permeability and increases expression of intestinal tight junction proteins in weaned ... LPS-challenged and chlorogenic acid (CHA) supplemented group (orally 20 mg/kg and 50 mg/kg body). Dietary supplementation with ... objectives of this study were to investigate whether chlorogenic acid (CHA) could improve the intestinal barrier integrity for ...
Caffeic Acids / administration & dosage*. Catechin / administration & dosage. Chlorogenic Acid / administration & dosage*. ... Zn absorption was significantly less in rats fed on chlorogenic acid or caffeic acid than in the control group. Catechin ... 0/Antioxidants; 0/Caffeic Acids; 0/Isotopes; 153-18-4/Rutin; 154-23-4/Catechin; 327-97-9/Chlorogenic Acid; 331-39-5/caffeic ... Different PP of nutritional interest (chlorogenic acid, caffeic acid, catechin and rutin) were studied using meals ...
Chlorogenic Acid Part of Plant Used: Seed Active Ingredients: Chlorogenic Acid CAS: 327-97-9 Molecular Formula: C16H18O9 ... Chlorogenic Acid KS-08 - KINGSCI Products Made In China, China Manufacturer. Factory Supply 100% Pure Natural Weight Loss Green ... Specification: 10%-98% Chlorogenic Acid Green coffee beans p.e. comes from the seeds of Coffea robusta or Coffea arabica. green ... Active Ingredients: Chlorogenic Acid CAS: 327-97-9 Molecular Formula: C16H18O9 Molecular Weight: 354.31 Appearance: Fine Light ...
Applied Food Sciences Issued Patent for Producing Guayusa Extract featuring Caffeine and Chlorogenic Acids. Applied Food ...
  • To investigate the mechanism of the combined effects of chlorogenic acid (CGA) and caffeine on lipid metabolism in high-fat diet-induced obese mice, eighty female ICR mice were randomly divided into eight groups and fed with a high-fat diet with/without CGA and/or caffeine for 14 weeks. (rsc.org)
  • In addition to chlorogenic acid from the green coffee, it contains choline (84 mg per serving), which contributes to the healthy metabolism of fat. (naturvital.info)
  • The non-covalent interactions between the monomeric phenolic compound chlorogenic acid (5-CQA) and bovine serum albumin (BSA), lysozyme, and α-lactalbumin were characterized, and their effect on protein properties was examined. (tudelft.nl)
  • The heterologous expression of globe artichoke HQT in E. coli showed that this enzyme can catalyze the esterification of quinic acid with caffeoyl-CoA or p -coumaroyl-CoA to generate, respectively, chlorogenic acid (CGA) and p -coumaroyl quinate. (biomedcentral.com)
  • Characterization of Protein Tyrosine Phosphatase 1B Inhibition by Chlorogenic Acid and Cichoric Acid. (nih.gov)
  • The leaves of globe artichoke and cultivated cardoon ( Cynara cardunculus L.) have significant pharmaceutical properties, which mainly result from their high content of polyphenolic compounds such as monocaffeoylquinic and dicaffeoylquinic acid (DCQ), and a range of flavonoid compounds. (biomedcentral.com)
  • Chlorogenic acids are among the most abundant phenolics found in the human diet. (usask.ca)
  • Recently, cichoric acid (CHA) and chlorogenic acid (CGA) were predicted by docking methods to be allosteric inhibitors that bind distal to the active site. (nih.gov)
  • Even though little direct information is as yet available concerning the biosynthesis of di- and tri-caffeoylquinic acid, the prior accumulation of CGA does appear to be necessary. (biomedcentral.com)
  • Objective] To establish a method for determining contents of chlorogenic acid in different organs from Taraxacum mongolicum by HPLC. (cnki.com.cn)
  • Method] The HPLC was carried out with Shim-pack VP-ODS column(4.6 mm×150.0 mm,5 μm) using mixture of methanol and 0.4 % phosphoric acid solution in different ratio as mobile phase.Other conditions were: flow rate of 1.0 ml/min,detection wavelength of 326 nm,column temperature of 40 ℃ and sampling amount of 20 μl. (cnki.com.cn)
  • In this study, we observed the protective effect of Lycium barbarum L. extract on RGCs in rats with persistent ocular hypertension and made qualitative and quantitative analyses on chlorogenic acid in the extract by RP-HPLC technique. (alliedacademies.org)
  • Gymnema Sylvestre Extract Product Name: Gymnema sylvestre Extract Botanical Name: Gymnema sylvestre .L Part Used : Stem and leaf Specification: 25%, 50% Gymnemic Acids Test method: HPLC CAS No.: 90045-47-9 Molecular Formula: C43H66O14 Molecular. (sino-excellent.com)
  • Echinacea Extract Latin name: Echinacea Purpurea extract Part used: overground part Appearance: Greenish yellow fine powder Specification: cichoric acid 1%,2%,4% HPLC Packing: packed in paper-drum and two plastic-bag inside. (sino-excellent.com)
  • Suppressive effects of chlorogenic acid on N-methyl-N-nitrosourea-indueed glandular stomach carcinogenesis in male F344 rats," Toxicological Sciences , vol. 24, no. 5, pp. 433-439, 1999. (hindawi.com)
  • Inhibitory effects of chlorogenic acid on azoxymethane-induced colon carcinogenesis in male F344 rats," Asian Pacific Organization for Cancer Prevention , vol. 3, no. 2, pp. 163-166, 2002. (hindawi.com)
  • Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice. (nih.gov)
  • We evaluated the neuroprotective effects of chlorogenic acid on learning and memory impairment induced by scopolamine (0.5 mg/kg, i.p.), a muscarinic antagonist, using the Y-maze, passive avoidance, and Morris water maze tests. (nih.gov)
  • This is the first study to investigate the acute effects of chlorogenic acid and trigonelline on glucose tolerance in humans. (diabetesjournals.org)
  • This systematic review discusses in vivo animal and human studies of the physiological and biochemical effects of chlorogenic acids (CGAs) on biomarkers of chronic disease. (nih.gov)
  • To investigate the mechanism of the combined effects of chlorogenic acid (CGA) and caffeine on lipid metabolism in high-fat diet-induced obese mice, eighty female ICR mice were randomly divided into eight groups and fed with a high-fat diet with/without CGA and/or caffeine for 14 weeks. (rsc.org)
  • Objective The current study investigates the effects of protective effects of chlorogenic acid (CGA) on d-galactose-induced liver and kidney injury. (edu.au)
  • Protective Effects of Chlorogenic Acid against Experimental Reflux Esophagitis in Rats. (medchemexpress.com)
  • On average, people consume about 10 times more polyphenols than they do vitamin C. Coffee contains a type of polyphenol called chlorogenic acids, which are esters of quinic and cinnamic acids. (livestrong.com)
  • A series of experiments reported in the scientific journal 'Circulation Research' focuses on two polyphenols in coffee, caffeic and ferulic acids. (livestrong.com)
  • As a natural plant extract, chlorogenic acid and other natural polyphenols can not only excellently protect collagen against the damage of reactive oxygen and other free radicals, but also effectively prevent human skin from the harmful effects resulted from UV radiation. (newleafherb.com)
  • Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols. (abmole.com)
  • In the first part of the review, we discuss the main gut microorganisms, particularly bacteria, and microbial pathways associated with the metabolism of dietary carbohydrates (to short chain fatty acids and gases), proteins, plant polyphenols, bile acids, and vitamins. (springer.com)
  • Chlorogenic Acid is an ester of the caffeic acid, and considered to be among the highly health-benefiting class of polyphenols. (organicnewsroom.com)
  • Chlorogenic Acid, along with other polyphenols, are well-regarded as highly-active natural anti-oxidants that can help reduce cellular damage throughout the body. (organicnewsroom.com)
  • 1.Green Coffee Bean Extract Chlorogenic acid, long known as an antioxidant with potential anti-cancer activity, also slows the release of glucose into bloodstream after a meal. (kitairu.net)
  • Coffee Bean Extract, Chlorogenic Acid, Herbal Extract manufacturer / supplier in China, offering Weight Loss Green Coffee Bean Extract Chlorogenic Acid, Styptic High Quality Couch Grass Extract/Arundoin, 10: 1 20: 1, Antineoplastic Natural Ligustrum Lucidum Extract 98% Oleanolic Acid and so on. (made-in-china.com)
  • A cinnamate ester obtained by formal condensation of the carboxy group of trans -caffeic acid with the 3-hydroxy group of quinic acid. (ebi.ac.uk)
  • Chlorogenic acid (CGA) is the ester of caffeic acid and (−)-quinic acid, functioning as an intermediate in lignin biosynthesis. (wikipedia.org)
  • The term "chlorogenic acids" refers to a related polyphenol family of esters, including hydroxycinnamic acids (caffeic acid, ferulic acid and p-coumaric acid) with quinic acid. (wikipedia.org)
  • Structurally, chlorogenic acid is the ester formed between caffeic acid and the 3-hydroxyl position of L-quinic acid. (wikipedia.org)
  • Isomers of chlorogenic acid include the caffeoyl ester at other hydroxyl sites on the quinic acid ring: 4-O-caffeoylquinic acid (cryptochlorogenic acid or 4-CQA) and 5-O-caffeoylquinic acid (neochlorogenic acid or 5-CQA). (wikipedia.org)
  • The order of numbering of atoms on the quinic acid ring was reversed in 1976 following IUPAC guidelines, with the consequence that 3-CQA became 5-CQA, and 5-CQA became 3-CQA. (wikipedia.org)
  • Another switchgrass hydroxycinnamoyl transferase, PvHCT-Like1, is phylogenetically distant from HCTs or HQTs, but exhibits HQT activity, preferring quinic acid as acyl acceptor, and could therefore function in CGA biosynthesis. (springer.com)
  • Chlorogenic acid is an ester of caffeic acid and quinic acid. (hmdb.ca)
  • This compound belongs to the class of chemical entities known as quinic acids and derivatives. (hmdb.ca)
  • These are compounds containing a quinic acid moiety (or a derivative thereof), which is a cyclitol made up of a cyclohexane ring that bears four hydroxyl groups at positions 1,3.4, and 5, as well as a carboxylic acid at position 1. (hmdb.ca)
  • Chlorogenic acid (CGA) is a natural chemical compound which is the ester of caffeic acid and (-)quinic acid. (kitairu.net)
  • That specific flavour is caused by a chemical compound known as chlorogenic acid which is found in abundance in coffee beans and is just one of the many acids that coffee beans contain such as lactic, malic, quinic, citric, and acetic acids. (greencoffeereport.org)
  • Once digested, our body metabolizes these acids in two types: caffeic and quinic acid . (greencoffeereport.org)
  • Chlorogenic acid is a group of esters created from trans-cinnamic acids and quinic acids that has many health benefits. (reference.com)
  • Three instant coffee extracts (light roast, dark roast, decaffeinated dark roast) and six coffee components [caffeine ( 1 ), chlorogenic acid ( 2 ), quinic acid ( 3 ), caffeic acid ( 4 ), quercetin ( 5 ), and phenylindane ( 6 )] were investigated for their ability to inhibit the fibrillization of Aβ and tau proteins using thioflavin T (ThT) and thioflavin S (ThS) fluorescence assays, respectively. (frontiersin.org)
  • Chlorogenic acid (CGA) is an ester formed from cinnamic acids and quinic acid and is also known as 5-O-caffeoylquinic acid (5-CQA) (IUPAC numbering) or 3-CQA (pre-IUPAC numbering) [ 7 ] . (eco-supplements.com)
  • Effect of chlorogenic acid on hydroxyl radical. (cdc.gov)
  • Pharmacologists at the National University of Singapore wanted to find out more about the effect of chlorogenic acid on the way insulin works, so they did a series of experiments using muscle cells from overweight mice that had type-2 diabetes. (ergo-log.com)
  • Its protective property might be due to the presence of a mitochondrial-targeted antioxidant effect of chlorogenic acid. (begellhouse.com)
  • What is Green Coffee Bean Extract Powder Chlorogenic Acid? (kitairu.net)
  • is 500 grams (1.1 lb, 17.6 oz) Green Coffee Bean Extract Powder (standardized 50% Chlorogenic Acid). (herbstoreusa.com)
  • For supplement purpose, daily dose for general adult is a flat 1/4 teaspoon powder (425 mg powder, resulting 215 mg chlorogenic acid and 19 mg caffeine) with water or beverage, 1 to 2 times daily. (herbstoreusa.com)
  • Pure Green Coffee Bean Extract bulk Powder, standardized 50% Chlorogenic Acid, with top quality at low price from $15.95. (herbstoreusa.com)
  • Recent evidence indicates that some colon-derived phenolic acids have in vitro anti-inflammatory activity. (mdpi.com)
  • Action of chlorogenic acid in vegetables and fruits as an inhibitor of 8-hydroxy-deoxyguanseine formation in vitro and in a rat carcinogenesis mode1," Food and Chemical Toxicology , vol. 38, no. 5, pp. 467-471, 2000. (hindawi.com)
  • Experimental study on the induction of a-tinterferon of human leucocyte in vitro by chlorogenic acid," Journal of Harbin Medical University , vol. 38, pp. 120-122, 2004. (hindawi.com)
  • In vitro, chlorogenic acid was found to inhibit acetylcholinesterase activity (IC₅₀=98.17 μg/ml) and free radical scavenging activity (IC₅₀=3.09 μg/ml) in a dose-dependent manner. (nih.gov)
  • According to this in-vitro study carnosic acid helps muscle cells to absorb more glucose. (ergo-log.com)
  • In vitro studies on the stability in the proximal gastrointestinal tract and bioaccessibility in Caco-2 cells of chlorogenic acids from spent coffee grounds. (semanticscholar.org)
  • In vitro transformation of chlorogenic acid by human gut microbiota. (semanticscholar.org)
  • A test in vitro antiproliferative activity of chlorogenic acid found in respect of a human tumor cell line ( A549 ) , which can not be explained with the sole antioxidant activity. (bamboolifetree.co.uk)
  • In vitro tests have demonstrated for chlorogenic acid , caffeic acid and the like for the ferulic acid , the ability to inhibit the reaction between nitrite and secondary amines or tertiary amines to form nitrosamines , strongly carcinogenic for the liver and kidneys ( Kono et al. (bamboolifetree.co.uk)
  • Chlorogenic acid inhibited the proliferation of A549 human cancer cells in vitro.Chlorogenic acid suppressed 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced neoplastic transformation of JB6 P+ cells in a dose-dependent manner.Chlorogenic acid also increased the enzymatic activities of glutathione S-transferases (GST) and NAD(P)H: quinone oxidoreductase. (abmole.com)
  • Chlorogenic acid (CGA), an important biologically active dietary polyphenol, is produced by certain plant species and is a major component of coffee. (nih.gov)
  • 5-O-caffeoylquinic acid is the most abundant polyphenol present in coffee. (livestrong.com)
  • Evaluation of the anti-inflammatory, analgesic and antipyretic activities of the natural polyphenol chlorogenic acid. (abmole.com)
  • Absorption and metabolism of caffeic acid and chlorogenic acid in the small intestine of rats. (biomedsearch.com)
  • Salinity Stress Is Beneficial to the Accumulation of Chlorogenic Acids in Honeysuckle (Lonicera japonica Thunb. (frontiersin.org)
  • This study aimed to examine the effects of salinity stress on accumulation of chlorogenic acids in honeysuckle, through hydroponic experiments and field trials, and to examine the mechanisms underlying the effects. (frontiersin.org)
  • Soil salinity also led to elevated chlorogenic acid concentrations in honeysuckle flower buds, with significant increases in total chlorogenic acids concentration of 22.42 and 25.14% in May 2014 and 2015, respectively. (frontiersin.org)
  • In conclusion, salinity stress improved the medicinal quality of honeysuckle by promoting accumulation of chlorogenic acids, however, the mechanisms underlying this process were not consistent in flower buds and leaves. (frontiersin.org)
  • Detection of Chlorogenic Acid in Honeysuckle Using Infrared-Assisted Extraction Followed by Capillary Electrophoresis with UV Detector. (ebscohost.com)
  • In this study, a novel infrared-assisted extraction method coupled capillary electrophoresis (CE) is employed to determine chlorogenic acid from a traditional Chinese medicine (TCM), honeysuckle. (ebscohost.com)
  • The almond skin enriched fraction obtained from cold-pressed oil residues of the endemic Moroccan Beldi ecotypes is particularly rich in chlorogenic acid. (preprints.org)
  • The present results show that chlorogenic acid is absorbed and hydrolysed in the small intestine. (biomedsearch.com)
  • The researchers were able to show that chlorogenic acid activated the glucose transporter GLUT4 via AMPK. (ergo-log.com)
  • Variations in caffeine and chlorogenic acid contents of coffees: what are we drinking? (rsc.org)
  • The main objective of this clinical trial is to investigate the possible difference in the bioavailability of chlorogenic and phenolic acids from coffee at various roasting levels. (clinicaltrials.gov)
  • If you want to make a bigger impact on metabolism, consider supplements that contain chlorogenic acid and caffeine. (livestrong.com)
  • Some metabolism-boosting supplements contain green coffee bean extract, which consists of the active ingredient chlorogenic acid. (livestrong.com)
  • Chlorogenic acid is an important intermediate in lignin biosynthesis. (kitairu.net)
  • Green Coffee Extract contains high levels of chlorogenic acids and ideal for those following a calorie controlled weight loss diet. (bodykind.com)
  • Natures Aid Green Coffee Extract is a decaffeinated Green Coffee Bean Extract this provides a guaranteed minimum 45% Chlorogenic Acid. (bodykind.com)
  • 1. Antioxidant effect: chlorogenic acid and its derivatives in green coffee extract have strong antioxidant effects. (gl-herb.com)
  • Gallic Acid is a trihydroxybenzoic acid, a type of phenolic acid. (thomassci.com)
  • Chlorogenic acid is freely soluble in ethanol and acetone. (wikipedia.org)
  • It is very soluble in ethanol and acetone, slightly soluble in acetic acid ethyl, and insoluble in chloroform, ether, benzene and other lipophilic organic solvents. (newleafherb.com)
  • Composite of pharmacokinetics: sum of AUC of chlorogenic and phenolic acids the of extreme treatments. (clinicaltrials.gov)
  • Composite of pharmacokinetics: AUC, Sum of AUC, Cmax, Tmax and T1/2 of plasma chlorogenic and phenolic acids from the other treatments. (clinicaltrials.gov)
  • accordingly, the concentrations of chlorogenic acids in leaves were significantly increased under NaCl stress, as was antioxidant activity. (frontiersin.org)
  • It should be noted that even the non-absorbed fraction of chlorogenic acid can still perform its antioxidant activity and protective at the level of the digestive tract , protecting against oxidative damage and therefore the risk of cancer of the stomach and intestines. (bamboolifetree.co.uk)
  • Structures having more than one caffeic acid group are called isochlorogenic acids, and can be found in coffee. (wikipedia.org)
  • Taken as a dietary supplement or in coffee, chlorogenic acid has been shown in review articles to have a small reduction in blood pressure, and remains under investigation for possible anti-inflammatory effects. (wikipedia.org)
  • Chlorogenic acid is a major polyphenolic component of many plants and beverages, and is particularly abundant in coffee. (nih.gov)
  • Chlorogenic acid is the major polyphenolic compound in coffee, isolated from the leaves and fruits of dicotyledonous plants. (hmdb.ca)
  • The chlorogenic acid content of a 200 ml (7-oz) cup of coffee has been reported to range from 70-350 mg, which would provide about 35-175 mg of caffeic acid. (hmdb.ca)
  • RESEARCH DESIGN AND METHODS We conducted a randomized crossover trial of the effects of 12 g decaffeinated coffee, 1 g chlorogenic acid, 500 mg trigonelline, and placebo (1 g mannitol) on glucose and insulin concentrations during a 2-h oral glucose tolerance test (OGTT) in 15 overweight men. (diabetesjournals.org)
  • Coffee is a major source of the phenolic compound chlorogenic acid ( 6 ) and the vitamin B3 precursor trigonelline ( 7 ), which have been shown to reduce blood glucose concentrations in animal studies ( 5 - 8 ). (diabetesjournals.org)
  • Four supplements were tested in this crossover trial: 12 g decaffeinated coffee (Nescafé Gold, Nestlé, the Netherlands), 1 g chlorogenic acid (Sigma Aldrich, Switzerland), 500 mg trigonelline (Sigma Aldrich), and 1 g mannitol as placebo (Spruyt Hillen Bufa, the Netherlands). (diabetesjournals.org)
  • Based on laboratory measurements ( 9 , 10 ), the decaffeinated coffee used in our study provided 264 mg chlorogenic acid and 72 mg trigonelline. (diabetesjournals.org)
  • The effect of roasting of coffee beans and the extraction of ground coffee with different volumes of hot pressurised water on the caffeine and the total caffeoylquinic acids (CQAs) content of the resultant beverages was investigated. (rsc.org)
  • Chlorogenic acid [structural formula below] is a prominent component of coffee and supplements that contain Green Coffee Bean extract. (ergo-log.com)
  • Drinking coffee protects against type-2 diabetes, and nutritionists suspect that this protective effect is partly due to chlorogenic acid. (ergo-log.com)
  • Daily supplementation with 300 milligrams of chlorogenic acids - the bioactive substances in Green Coffee Bean extract - can slightly reduce the amount of belly fat. (ergo-log.com)
  • One group received regular instant coffee, the other coffee to which the researchers had added around 300 milligrams of chlorogenic acid analogues. (ergo-log.com)
  • Besides caffeine, chlorogenic acid analogues are the most important bioactive constituents of coffee. (ergo-log.com)
  • According to a human clinical trial comparing daily consumption of roasted coffee containing 359 mg chlorogenic acids and placebo coffee for one week, repeated consumption of chlorogenic acids decreased the respiratory quotient and increased oxygen consumption, which means that both energy expenditure and fat oxidation were increased. (ergo-log.com)
  • Furthermore, feeding green coffee bean extract containing chlorogenic acids to mice with diet-induced obesity affects body fat accumulation, with a dose-dependent inhibition of the increase in body weight and accumulation of visceral fat and liver fat. (ergo-log.com)
  • Consumption of high-chlorogenic acids coffee for 12 weeks by overweight adults might lower visceral fat area, total abdominal fat area, BMI, and waist circumference ", conclude the researchers. (ergo-log.com)
  • green coffee beans p.e., the weight loss is due to chlorogenic acid, which is thought to reduce the absorption of glucose and lower the hyperglycemic peak. (diytrade.com)
  • Start your review of Super Garcinia Cambogia 300 Liquid (50% HCA) with Green Coffee Bean Extract (50% Chlorogenic Acid) Weight Loss Diet Drops - 2fl Oz (60ml)! (influenster.com)
  • Dose-dependent absorption of chlorogenic acids in the small intestine assessed by coffee consumption in ileostomists. (semanticscholar.org)
  • The roasting process does not influence the extent of conjugation of coffee chlorogenic and phenolic acids. (semanticscholar.org)
  • Chlorogenic acid and coffee prevent hypoxia-induced retinal degeneration. (semanticscholar.org)
  • Chlorogenic acids-present in coffee, fruits, and vegetables-was associated with a lower incidence of breast cancer among postmenopausal women. (greenmedinfo.com)
  • Within a coffee bean is a CGA called 5-caffeoylquinic acid. (greencoffeereport.org)
  • 50 % Chlorogenic Acid Green Coffee cod. (bamboolifetree.co.uk)
  • Ingredients for 1 vegetarian capsule : Coffee- Only Pure dry extract titrated green seeds ( Coffee arabica L.) 490 mg - (Title 50 % Chlorogenic Acid , intake of 245 mg). (bamboolifetree.co.uk)
  • The molecule of chlorogenic acid , commonly prevalent in foods such as coffee and certain plants, collecting special interest in nutrition and has been studied for its antioxidant , antibacterial and antiviral properties , and in general for potentially preventive activity against tumor diseases , cardiovascular disease and diabetes. (bamboolifetree.co.uk)
  • One candidate is trigonelline, a nicotinic acid in coffee that lowers blood sugar in animal studies. (livestrong.com)
  • Green Coffee Bean is a powerful antioxidant and its chlorogenic acids advances weight loss by decreasing the rate of fat absorption from food, cutting down fat storage in the liver, and enhancing the fat burning capacity of the hormone adiponectin. (herbadiet.in)
  • Our Green Coffee contains a super high-potency extract of Coffea Robusta beans standardized for 50% Chlorogenic Acid & is lab tested for potency and purity. (herbadiet.in)
  • Chlorogenic acid is a major phenolic compound in coffee and tea. (medchemexpress.com)
  • Green coffee bean extract 50 % Chlorogenic Acid_Product Center_Xi'an Green Life Natural Products Co., Ltd. (gl-herb.com)
  • Pure Heatlh Naturally Pure Green Coffee Bean - 45% Chlorogenic Acids! (consumerlab.com)
  • Loquat leaf extract contains a triterpenoid compound known as corosolic acid which has actions in stimulating glucose transport into cells. (chinaplantextract.com)
  • Both the chlorogenic acids and the flavan-3-ols are absorbed in the small intestine and appear in the circulatory system predominantly as glucuronide, sulfate and methylated metabolites. (mdpi.com)
  • Chlorogenic acid was shown to have an antagonistic effect on glucose transport and also has been found to significantly delay glucose uptake from the small intestine. (pe-factory.com)
  • RESULTS Chlorogenic acid and trigonelline ingestion significantly reduced glucose (−0.7 mmol/l, P = 0.007, and −0.5 mmol/l, P = 0.024, respectively) and insulin (−73 pmol/l, P = 0.038, and −117 pmol/l, P = 0.007) concentrations 15 min following an OGTT compared with placebo. (diabetesjournals.org)
  • CONCLUSIONS Chlorogenic acid and trigonelline reduced early glucose and insulin responses during an OGTT. (diabetesjournals.org)
  • Chlorogenic acid increases muscle cells' insulin sensitivity and chases glucose into these cells. (ergo-log.com)
  • Administering chlorogenic acid boosted the glucose uptake, certainly when combined with insulin. (ergo-log.com)
  • Chlorogenic acid (CHL), the most potent functional inhibitor of the microsomal glucose-6-phosphate translocase (G6PT), is thought to possess cancer chemopreventive properties. (biomedcentral.com)
  • That is Green Coffe Bean Extrac , the weight loss is due to chlorogenic acid, which is thought to reduce the absorption of glucose and lower the hyperglycemic peak.The indications for use of this supplement are: Obesity, low MBR, cellulite and extra weight. (pe-factory.com)
  • Indole-3-acetic acid (IAA) is the most common, naturally-occurring, plant growth regulator - as a principal auxin of higher plants. (thomassci.com)
  • Trichloroacetic acid is an acetic acid analogue commonly used to precipitate proteins, DNA and RNA. (thomassci.com)
  • Chlorogenic acid (CGA, caffeoyl quinate) is the major soluble phenolic compound in switchgrass, and the lignin and CGA biosynthetic pathways potentially share intermediates and enzymes. (springer.com)
  • Mechanism of action and interactions between xanthine oxidase inhibitors derived from natural sources of chlorogenic and ferulic acids. (scienceopen.com)
  • In a mouse study by Korean researchers, extract of Urtica thunbergiana, which is rich with chlorogenic acid, was linked to better skin hydration. (nutraingredients-usa.com)
  • Korean researchers studied skin health benefits of chlorogenic acid, an active component found in extract of the plant Urtica thunbergiana ​, which has been used medicinally in East Asia and is a common ingredient in soups and stews. (nutraingredients-usa.com)
  • After researchers reviewed seven previously published studies, they concluded that chlorogenic acid causes a moderate reduction in systolic and diastolic blood pressure, reported the Journal of Human Hypertension in February 2015. (livestrong.com)
  • The elusive search for pre-eclampsia prevention rumbles on as researchers find not even a high dose of folic acid is enough to ward off the condition in high-risk women. (nutraingredients-usa.com)
  • Applied Food Sciences Inc. (AFS) is pleased to announce it is the exclusive owner of U.S. Patent #9345707, a process patent that covers the production of enriched natural guayusa, from a single source plant, containing antioxidants, amino acids and caffeine. (naturalproductsinsider.com)
  • Laboratory studies have shown that chlorogenic acid contains high amount of antioxidants. (greencoffeereport.org)
  • Capillary electrophoresis with electrochemical detection has been employed for the determination of p-hydroxyacetophenone, chlorogenic acid, and caffeic acid in Herba Artemisiae Scopariae (the dried sprout of Artemisia scoparia Waldst. (ebscohost.com)
  • Determination of uric acid in human saliva by capillary electrophoresis with electrochemical detection: potential application in fast diagnosis of gout. (ebscohost.com)
  • The present method is accurate, sensitive and highly specific, which can be used for determination of chlorogenic acid content in Verbena officinalis L. and its extract. (biomedres.info)
  • To help me with this is been taking Chlorogenic Acid supplements. (dadamo.com)
  • We'd take this a step further and envisage a future where chlorogenic acid is used in carbohydrate supplements for endurance athletes, calorie-rich post-workout products with fast sugars for strength athletes, and diet products for people who want to lose weight in an intelligent way. (ergo-log.com)
  • Chlorogenic acid might be suitable for use in bodybuilding, slimming and endurance sports supplements, according to a study done at the National University of Singapore. (ergo-log.com)
  • Choose supplements that contain one or more evidence-backed ingredients, such as caffeine plus chlorogenic acid, EGCG or capsaicin. (livestrong.com)
  • Decreased expression of stearoyl-CoA desaturase 1 and ACC1, which are involved in fatty-acid synthesis, promotes energy expenditure, and decreased ACC2 expression increases fatty-acid oxidation in the mitochondria through the reduced production of malonyl CoA, which inhibits carnitine palmitoyltransferase 1. (ergo-log.com)
  • Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway. (medchemexpress.com)
  • Further studies indicated that chlorogenic acid could stimulate the nuclear translocation of Nrf2 (NF-E2-related factor) as well as subsequent induction of GSTA1 antioxidant response element (ARE)-mediated GST activity.Chlorogenic acid inhibits Bcr-Abl (the fusion protein of Bcr and c-Abl) tyrosine kinase and triggers MAP kinases p38-dependent apoptosis. (abmole.com)
  • Effect of domestic cooking on human bioavailability of naringenin, chlorogenic acid, lycopene and beta-carotene in cherry tomatoes. (sigmaaldrich.com)
  • The chlorogenic acid of Eucommia ulmoides Oliv has strong anti-inflammatory and anti-inflammatory effects, and the anthocyanins and their polymers have obvious bacteriostasis, and the anthocyanins have inhibitory effect on Gram-negative and positive bacteria. (natural-ingredient.com)
  • Modern pharmacological experiments have proved that chlorogenic acid in Eucommia ulmoides has the effect of anticancer and cancer suppression. (natural-ingredient.com)
  • Japanese scholars have studied the antigenicity of chlorogenic acid in Eucommia ulmoides, and found that this effect is related to the antiantogenic components of chlorogenic acid, and explains the significance of chlorogenic acid in the prevention of cancer. (natural-ingredient.com)