A greenish-yellow, diatomic gas that is a member of the halogen family of elements. It has the atomic symbol Cl, atomic number 17, and atomic weight 70.906. It is a powerful irritant that can cause fatal pulmonary edema. Chlorine is used in manufacturing, as a reagent in synthetic chemistry, for water purification, and in the production of chlorinated lime, which is used in fabric bleaching.
Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)
A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.
Any of several processes in which undesirable impurities in water are removed or neutralized; for example, chlorination, filtration, primary treatment, ion exchange, and distillation. It includes treatment of WASTE WATER to provide potable and hygienic water in a controlled or closed environment as well as provision of public drinking water supplies.
Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms.
United States Indian Health Service
Indians, North American
Health Services, Indigenous
Porphyria Cutanea Tarda
An autosomal dominant or acquired porphyria due to a deficiency of UROPORPHYRINOGEN DECARBOXYLASE in the LIVER. It is characterized by photosensitivity and cutaneous lesions with little or no neurologic symptoms. Type I is the acquired form and is strongly associated with liver diseases and hepatic toxicities caused by alcohol or estrogenic steroids. Type II is the familial form.
An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA.
A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
A disorder of iron metabolism characterized by a triad of HEMOSIDEROSIS; LIVER CIRRHOSIS; and DIABETES MELLITUS. It is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (Jablonski's Dictionary of Syndromes & Eponymic Diseases, 2d ed)
Occupational Health Services
Database Management Systems
Threshold Limit Values
Standards for limiting worker exposure to airborne contaminants. They are the maximum concentration in air at which it is believed that a particular substance will not produce adverse health effects with repeated daily exposure. It can be a time-weighted average (TLV-TWA), a short-term value (TLV-STEL), or an instantaneous value (TLV-Ceiling). They are expressed either as parts per million (ppm) or milligram per cubic meter (mg/m3).
Air Pollutants, Occupational
Maximum Allowable Concentration
The maximum exposure to a biologically active physical or chemical agent that is allowed during an 8-hour period (a workday) in a population of workers, or during a 24-hour period in the general population, which does not appear to cause appreciable harm, whether immediate or delayed for any period, in the target population. (From Lewis Dictionary of Toxicology, 1st ed)
A province of Canada lying between the provinces of Manitoba and Quebec. Its capital is Toronto. It takes its name from Lake Ontario which is said to represent the Iroquois oniatariio, beautiful lake. (From Webster's New Geographical Dictionary, 1988, p892 & Room, Brewer's Dictionary of Names, 1992, p391)
Mammary Neoplasms, Experimental
The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.
Draft Skin Notation Profile: Chlorodiphenyl (54% chlorine) | NIOSH | CDC
Required Elements for Initial Public Posting. Subject: NIOSH Skin Notation Profile. Purpose: Provides information about the health risks associated with dermal contact and uptake of a specific workplace chemical.. Timing of Review: March 2019 - May 2019.. Primary Disciplines or Expertise Needed for Review: Toxicology, risk assessment, industrial hygiene, occupational medicine.. Type of Review: Individual. Number of Reviewers: 2-3 reviewers. Reviewers Selected by: NIOSH. Public Nominations Requested for Reviewers: No. Opportunities for the Public to Comment: Yes. Peer Reviewers Provided with Public Comments Before Their Review: No. Charge to Peer Reviewers. Reviewers are asked to consider the following review questions:. ...
CDC - NIOSH Pocket Guide to Chemical Hazards - Chlorodiphenyl (54% chlorine)
Chlorodiphenyl (54% Chlorine) Summary Report | CureHunter
Indian Health Manual (IHM) - Home
Uroporphyria in the uroporphyrinogen decarboxylase-deficient mouse: Interplay with siderosis and polychlorinated biphenyl...
Human Gene PML (uc002awm.3) Description and Page Index
Haz-Map Category Details
... chlorine) Agent Name. Chlorodiphenyl (54% chlorine). Alternative Name. PCBs (Polychlorinated biphenyls) ... Other animal data: Chlorodiphenyl (42% Cl) had no discernable effects in cats, rabbits, guinea pigs, rats, and mice after 150 ... Other animal data: Chlorodiphenyl (42% Cl) had no discernable effects in cats, rabbits, guinea pigs, rats, and mice after 150 ... and mice exposed to 1.5 mg/m3 of chlorodiphenyl (54% Cl) for 7 hours/day for 150 days; 5.4 mg/m3 resulted in more extensive but ...
Law Document English View | Ontario.ca
NIOSHTIC-2 Search Results - Basic View
Mphosph6 (M phase phosphoprotein 6) - Rat Genome Database
VPS16 (VPS16 core subunit of CORVET and HOPS complexes) - Rat Genome Database
Cancer Institute, Mechanisms of Carcinogenesis - Research Output - Penn State
Chapes, S. K., Mastro, A. M., Sonnenfeld, G. & Berry, W. D., Jan 1 1993, In : Journal of Leukocyte Biology. 54, 3, p. 227-235 9 ... 54, 3, p. 214-226 13 p.. Research output: Contribution to journal › Article ... 54-63 10 p.. Research output: Contribution to journal › Article ... Chlorodiphenyl (54% Chlorine) Dimethylnitrosamine ...
Aqueous exposure to Aroclor 1254 modulates the mitogenic response of Atlantic salmon anterior kidney T-cells: Indications of...
TY - JOUR. T1 - Aqueous exposure to Aroclor 1254 modulates the mitogenic response of Atlantic salmon anterior kidney T-cells. T2 - Indications of short- and long-term immunomodulation. AU - Iwanowicz, Luke R.. AU - Lerner, Darren T.. AU - Blazer, Vicki S.. AU - McCormick, Stephen D.. PY - 2005/5/15. Y1 - 2005/5/15. N2 - Polychlorinated biphenyls (PCBs) exist as persistent organic pollutants in numerous river systems in the United States. Unfortunately, some of these rivers are sites of active Atlantic salmon restoration programs, and polychlorinated biphenyls have been implicated as ancillary factors contributing to failed salmon restoration. Here, we investigate the immediate and chronic effects of intermediate duration aqueous PCB exposure (1 or 10 μg L-1 Aroclor 1254) on the mitogen-stimulated lymphoproliferative response of Atlantic salmon anterior kidney leukocytes (AKLs). A short-term study was designed to examine immunomodulation in Atlantic salmon smolts immediately following 21 days of ...
Stereoselective metabolism of the environmental mammary carcinogen 6-nitrochrysene to trans-1,2-dihydroxy-1,2-dihydro-6...
Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo<...
Gary Westbrook - Publications - Oregon Health & Science University
DeCS 2009 - Changed terms
FREDERIC SILVESTRE - Fingerprint - the Research Portal - University of Namur
Safety Center Company - Personal Protective Equipment
Dongho Geum - Research output - Korea University
Solvent Poisoning,and Occupational cancer, my story. - ACCforum
NIOSHTIC-2 Publications Search - 00080959 - NIOSH analytical method chlorodiphenyl (54% Chlorine) S121.
... chlorine) in particulate matter, involving the collection of a known volume of air through a cellulose membrane filter, ... A method for the determination of chlorodiphenyl (54% chlorine) in particulate matter, involving the collection of a known ... Organo-chlorine-compounds; Analytical-Method; Chromatographic-analysis; Sampling-methods; Airborne-particulates; Quantitative- ... A method for the determination of chlorodiphenyl (54% ...
The inhibitory effects of polychlorinated biphenyl Aroclor 1254 on Leydig cell LH receptors, steroidogenic enzymes and...
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Recent Regulatory Developments | The ACTA Group, L.L.C.
... announced the availability of Skin Notation Profiles for Chlorodiphenyl (42% chlorine) (Chemical Abstracts Service (CAS) Number ... EPA Evaluates 54 Conditions Of Use For TCE, Finding That 52 Present An Unreasonable Risk: On November 24, 2020, EPA released ... Of the 54 conditions of use that EPA reviewed, EPA found that 52 present an unreasonable risk to workers, occupational non- ...
- All exposure limits are defined in the legislation as chlorodiphenyl except for Ontario that defines the limit as polychlorinated biphenyls. (carexcanada.ca)
- NIOSH analytical method chlorodiphenyl (54% Chlorine ) S121. (cdc.gov)
- PCBs are a group of man-made organic chemicals consisting of carbon, hydrogen and chlorine atoms. (epa.gov)
- Other animal data: Chlorodiphenyl (42% Cl) had no discernable effects in cats, rabbits, guinea pigs, rats, and mice after 150 sevenhour exposures to 1.9 mg/m3 over 7 months [Treon et al. (nih.gov)
- Recovery of chlorine and iron oxide from ferric chloride. (cdc.gov)