The sodium salt of BENZOIC ACID. It is used as an antifungal preservative in pharmaceutical preparations and foods. It may also be used as a test for liver function.
Substances capable of inhibiting, retarding or arresting the process of fermentation, acidification or other deterioration of foods.
Rare congenital metabolism disorders of the urea cycle. The disorders are due to mutations that result in complete (neonatal onset) or partial (childhood or adult onset) inactivity of an enzyme, involved in the urea cycle. Neonatal onset results in clinical features that include irritability, vomiting, lethargy, seizures, NEONATAL HYPOTONIA; RESPIRATORY ALKALOSIS; HYPERAMMONEMIA; coma, and death. Survivors of the neonatal onset and childhood/adult onset disorders share common risks for ENCEPHALOPATHIES, METABOLIC, INBORN; and RESPIRATORY ALKALOSIS due to HYPERAMMONEMIA.
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
Salts and esters of hippuric acid.
Elevated level of AMMONIA in the blood. It is a sign of defective CATABOLISM of AMINO ACIDS or ammonia to UREA.
Derivatives of BENZOIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxybenzene structure.
A bile pigment that is a degradation product of HEME.
A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
Accumulation of BILIRUBIN, a breakdown product of HEME PROTEINS, in the BLOOD during the first weeks of life. This may lead to NEONATAL JAUNDICE. The excess bilirubin may exist in the unconjugated (indirect) or the conjugated (direct) form. The condition may be self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) or pathological with toxic levels of bilirubin.
A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules.
A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
A condition characterized by an abnormal increase of BILIRUBIN in the blood, which may result in JAUNDICE. Bilirubin, a breakdown product of HEME, is normally excreted in the BILE or further catabolized before excretion in the urine.
Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.
Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.
Exclusive legal rights or privileges applied to inventions, plants, etc.
A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.
Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.
Organized activities related to the storage, location, search, and retrieval of information.
Rare congenital X-linked disorder of lipid metabolism. Barth syndrome is transmitted in an X-linked recessive pattern. The syndrome is characterized by muscular weakness, growth retardation, DILATED CARDIOMYOPATHY, variable NEUTROPENIA, 3-methylglutaconic aciduria (type II) and decreases in mitochondrial CARDIOLIPIN level. Other biochemical and morphological mitochondrial abnormalities also exist.
A plant genus of the family CELASTRACEAE that is a source of triterpenoids and diterpene epoxides such as triptolide.
Voluntary cooperation of the patient in taking drugs or medicine as prescribed. This includes timing, dosage, and frequency.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.
A cell line derived from cultured tumor cells.
The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
Neoplasms composed of glandular tissue, an aggregation of epithelial cells that elaborate secretions, and of any type of epithelium itself. The concept does not refer to neoplasms located in the various glands or in epithelial tissue.
Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.
General term for CYSTS and cystic diseases of the OVARY.
Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.
Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.
A biocompatible polymer used as a surgical suture material.
Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
Sites on an antigen that interact with specific antibodies.
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
A large family of cell surface receptors that bind conserved molecular structures (PAMPS) present in pathogens. They play important roles in host defense by mediating cellular responses to pathogens.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
The veins and arteries of the HEART.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.

Heterologous expression of the vanadium-containing chloroperoxidase from Curvularia inaequalis in Saccharomyces cerevisiae and site-directed mutagenesis of the active site residues His(496), Lys(353), Arg(360), and Arg(490). (1/107)

The vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis is heterologously expressed to high levels in the yeast Saccharomyces cerevisiae. Characterization of the recombinant enzyme reveals that this behaves very similar to the native chloroperoxidase. Site-directed mutagenesis is performed on four highly conserved active site residues to examine their role in catalysis. When the vanadate-binding residue His(496) is changed into an alanine, the mutant enzyme loses the ability to bind vanadate covalently resulting in an inactive enzyme. The negative charges on the vanadate oxygens are compensated by hydrogen bonds with the residues Arg(360), Arg(490), and Lys(353). When these residues are changed into alanines the mutant enzymes lose the ability to effectively oxidize chloride but can still function as bromoperoxidases. A general mechanism for haloperoxidase catalysis is proposed that also correlates the kinetic properties of the mutants with the charge and the hydrogen-bonding network in the vanadate-binding site.  (+info)

Striking activation of oxidative enzymes suspended in nonaqueous media. (2/107)

The catalytic activity of four lyophilized oxidative enzymes-horseradish peroxidase, soybean peroxidase, Caldariomyces fumago chloroperoxidase, and mushroom polyphenol oxidase-is much lower when directly suspended in organic solvents containing little water than when they are introduced into the same largely nonaqueous media by first dissolving them in water and then diluting with anhydrous solvents. The lower the water content of the medium, the greater this discrepancy becomes. The mechanism of this phenomenon was found to arise from reversible denaturation of the oxidases on lyophilization: because of its conformational rigidity, the denatured enzyme exhibits very limited activity when directly suspended in largely nonaqueous media but renatures and thus yields much higher activity if first redissolved in water. Two independent means were discovered for dramatically minimizing the lyophilization-induced inactivation, both involving the addition of certain types of excipients to the aqueous enzyme solution before lyophilization. The first group of excipients consists of phenolic and aniline substrates as well as other hydrophobic compounds; these presumably bind to the hydrophobic pocket of the enzyme active site, thereby preventing its collapse during dehydration. The second group consists of general lyoprotectants such as polyols and polyethylen glycol that apparently preserve the overall enzyme structure during dehydration. The activation effects of such excipients can reach into the tens and hundreds of fold. Moreover, the activations afforded by the two excipient groups are additive, resulting in up to a complete protection against lyophilization-induced inactivation when representatives of the two are present together.  (+info)

Replacement of the proximal heme thiolate ligand in chloroperoxidase with a histidine residue. (3/107)

Chloroperoxidase is a versatile heme enzyme which can cross over the catalytic boundaries of other oxidative hemoproteins and perform multiple functions. Chloroperoxidase, in addition to catalyzing classical peroxidative reactions, also acts as a P450 cytochrome and a potent catalase. The multiple functions of chloroperoxidase must be derived from its unique active site structure. Chloroperoxidase possesses a proximal cysteine thiolate heme iron ligand analogous to the P450 cytochromes; however, unlike the P450 enzymes, chloroperoxidase possesses a very polar environment distal to its heme prosthetic group and contains a glutamic acid residue in close proximity to the heme iron. The presence of a thiolate ligand in chloroperoxidase has long been thought to play an essential role in its chlorination and epoxidation activities; however, the research reported in this paper proves that hypothesis to be invalid. To explore the role of Cys-29, the amino acid residue supplying the thiolate ligand in chloroperoxidase, Cys-29 has been replaced with a histidine residue. Mutant clones of the chloroperoxidase genome have been expressed in a Caldariomyces fumago expression system by using gene replacement rather than gene insertion technology. C. fumago produces wild-type chloroperoxidase, thus requiring gene replacement of the wild type by the mutant gene. To the best of our knowledge, this is the first time that gene replacement has been reported for this type of fungus. The recombinant histidine mutants retain most of their chlorination, peroxidation, epoxidation, and catalase activities. These results downplay the importance of a thiolate ligand in chloroperoxidase and suggest that the distal environment of the heme active site plays the major role in maintaining the diverse activities of this enzyme.  (+info)

Peroxidase and phosphatase activity of active-site mutants of vanadium chloroperoxidase from the fungus Curvularia inaequalis. Implications for the catalytic mechanisms. (4/107)

Mutation studies were performed on active-site residues of vanadium chloroperoxidase from the fungus Curvularia inaequalis, an enzyme which exhibits both haloperoxidase and phosphatase activity and is related to glucose-6-phosphatase. The effects of mutation to alanine on haloperoxidase activity were studied for the proposed catalytic residue His-404 and for residue Asp-292, which is located close to the vanadate cofactor. The mutants were strongly impaired in their ability to oxidize chloride but still oxidized bromide, although they inactivate during turnover. The effects on the optical absorption spectrum of vanadium chloroperoxidase indicate that mutant H404A has a reduced affinity for the cofactor, whereas this affinity is unchanged in mutant D292A. The effect on the phosphatase activity of the apoenzyme was investigated for six mutants of putative catalytic residues. Effects of mutation of His-496, Arg-490, Arg-360, Lys-353, and His-404 to alanine are in line with their proposed roles in nucleophilic attack, transition-state stabilization, and leaving-group protonation. Asp-292 is excluded as the group that protonates the leaving group. A model based on the mutagenesis studies is presented and may serve as a template for glucose-6-phosphatase and other related phosphatases. Hydrolysis of a phospho-histidine intermediate is the rate-determining step in the phosphatase activity of apochloroperoxidase, as shown by burst kinetics.  (+info)

X-ray structures of a novel acid phosphatase from Escherichia blattae and its complex with the transition-state analog molybdate. (5/107)

The structure of Escherichia blattae non-specific acid phosphatase (EB-NSAP) has been determined at 1.9 A resolution with a bound sulfate marking the phosphate-binding site. The enzyme is a 150 kDa homohexamer. EB-NSAP shares a conserved sequence motif not only with several lipid phosphatases and the mammalian glucose-6-phosphatases, but also with the vanadium-containing chloroperoxidase (CPO) of Curvularia inaequalis. Comparison of the crystal structures of EB-NSAP and CPO reveals striking similarity in the active site structures. In addition, the topology of the EB-NSAP core shows considerable similarity to the fold of the active site containing part of the monomeric 67 kDa CPO, despite the lack of further sequence identity. These two enzymes are apparently related by divergent evolution. We have also determined the crystal structure of EB-NSAP complexed with the transition-state analog molybdate. Structural comparison of the native enzyme and the enzyme-molybdate complex reveals that the side-chain of His150, a putative catalytic residue, moves toward the molybdate so that it forms a hydrogen bond with the metal oxyanion when the molybdenum forms a covalent bond with NE2 of His189.  (+info)

Prochiral selectivity in H(2)O(2)-promoted oxidation of arylalkanols catalysed by chloroperoxidase. The role of the interactions between the OH group and the amino-acid residues in the enzyme active site. (6/107)

The H(2)O(2)-promoted oxidations of (R)-[alpha-(2)H(1)]-and (S)-[alpha-(2)H(1)]-arylalkanols catalysed by chloroperoxidase (CPO) from Caldariomyces fumago have been investigated. It has been found that with (R)-[alpha-(2)H(1)]-alcohols, the oxidation involves almost exclusively the cleavage of the C-H bond, whereas in the case of the oxidation of (S)-[alpha-(2)H(1)]-alcohols, the C-D bond is preferentially broken. These results clearly indicate that the reactions of corresponding undeuterated arylalkanols are characterized by a high prochiral selectivity, involving the cleavage of the pro-S C-H bond. This prochiral selectivity is poorly influenced by the electronic effect of ring substituents, whereas it decreases with the length of the carbon lateral chain, in the order: benzyl alcohol > 2-phenylethanol > 3-phenylpropanol. Molecular binding studies showed that the main factor directing the docking of the substrate in such a specific orientation in the enzyme active site is the interaction between the alcoholic OH group and the residue Glu183. This interaction is likely to drive both the stereochemistry and the regiochemistry of these reactions. A bifurcated hydrogen bond involving the OH group, the carboxylate oxygen of Glu183 and the oxoferryl oxygen might also be operating.  (+info)

Expression of the Caldariomyces fumago chloroperoxidase in Aspergillus niger and characterization of the recombinant enzyme. (7/107)

The Caldariomyces fumago chloroperoxidase was successfully expressed in Aspergillus niger. The recombinant enzyme was produced in the culture medium as an active protein and could be purified by a three-step purification procedure. The catalytic behavior of recombinant chloroperoxidase (rCPO) was studied and compared with that of native CPO. The specific chlorination activity (47 units/nmol) of rCPO and its pH optimum (pH 2.75) were very similar to those of native CPO. rCPO catalyzes the oxidation of various substrates in comparable yields and selectivities to native CPO. Indole was oxidized to 2-oxindole with 99% selectivity and thioanisole to the corresponding R-sulfoxide (enantiomeric excess >98%). Incorporation of (18)O from labeled H(2)18O(2) into the oxidized products was 100% in both cases.  (+info)

Roles of water in heme peroxidase and catalase mechanisms. (8/107)

A water molecule is coproduced with the Compound I intermediate in the reactions of native heme peroxidases and catalases with hydrogen peroxide. As a result of water release/rebinding from/to the coproduct formation site the Compound I intermediate may exist in two forms: a "wet" form, Compound I(H(2)O), in which a water molecule is present at or near the site of coproduct water formation, and Compound I, in which the coproduct water formation site is "dry." It is postulated that the absence or presence of a water molecule at this site provides the structural basis for a redox pathway switching mechanism, such that the transition states for 2-electron equivalent reduction of Compound I intermediates are accessible in the dry form, but that in the wet form only 1-electron equivalent processes are possible, unless release of water can be stimulated. This concept provides the basis of a general mechanism in which the classical functional distinction between catalases and peroxidases, as well as the more complex behavior observed in halide oxidation and halogenation reactions, appear as particular cases in which variations in the degree of retention of water at the coproduct formation site influence Compound I reactivity.  (+info)

Microfiche of typescript. [Urbana, Ill.]: Photographic Services, University of Illinois, U of I Library, [1988]. 2 microfiches (61 frames): negative ...
TY - JOUR. T1 - Chloroperoxidase‐Catalyzed Achmatowicz Rearrangements. AU - Thiel, Daniel. AU - Blume, Fabian. AU - Jäger, Christina. AU - Deska, Jan. PY - 2018/6/7. Y1 - 2018/6/7. N2 - Chloroperoxidase from Caldariomyces fumago catalyzes the selective oxidation of furfuryl alcohols in an Achmatowicz‐type ring expansion. In combination with glucose oxidase as oxygen‐activating biocatalyst, a purely enzymatic, aerobic protocol for the synthesis of 6‐hydroxypyranone building blocks is obtained. Thanks to an only modest stereochemical bias of the oxygenating heme protein, optically active alcohols of either configuration are converted without a significant mismatch opening up opportunities for enantioselective multienzymatic cascades. Balancing the oxidase‐driven aerobic activation, extended enzyme half‐lives and productive conversion of poorly soluble and slowly reacting substrates can be achieved with high yields of the six‐membered O‐heterocycles.. AB - Chloroperoxidase from ...
Synonyms for Aminium in Free Thesaurus. Antonyms for Aminium. 1 synonym for ammonium: ammonium ion. What are synonyms for Aminium?
광여기된 안트라센은 N,N-dimethylaniline(DMA)과 같은 기저 상태의 전자주개와 안정한 착물인 excited complex(exciplex)를 형성하는 것으로 잘 알려져 있다. 본 연구에서는 exciplex 형성 및 분해 반응에 미치는 전자주개의 구조적인 영향을 알아보기 위해 DMA 유도체인 N,N-dimethyl-o-toluidine(DMOT), N,N-dimethyl-m-toluidine(DMMT), N,N-dimethyl-p-toluidine(DMPT), 4-tert-butyl-dimethylaniline(BDMA), N,N,2,4,6-pentamethylaniline(PMA) 등을 사용하였다. 측정 방법으로는 absorption과 emission 및 time resolved spectroscopy를 이용하였다. DMA 페닐 링의 meta나 para 위치 치환은 안트라센과의 exciplex 형성에 영향을 미치지 않았다. 특히 para위치에 tertiary 부틸기가 붙은 BDMA는 메틸 기가 붙은 DMPT와 비슷한 결과를 보여 para 위치에 치환된 그룹의 크기는 exciplex 형성에 큰 영향을 주지 않음을 알 수 있었다. 이와 달리, ortho 위치의 치환은 ...
Find Cheap Price 99%N, N-Dimethylaniline Manufacture In Stock from China Manufacturer, Manufactory, Factory and Supplier - Mit-Ivy Industry Company on ECVV.com
Useful resin for solid phase Wittig reactions as well as solid phase Staudinger-aza-Wittig reactions. This polymer bound triphenylphosphin has also been used for halogenation reactions as well as a scavenger resin for alkyl halides and palladium. Other applications are the use as a polymer bound ligand for transition metals in transition metal catalyzed reactions. Other capacities and particle sizes on request ...
MolCore offers CAS No.10108-86-8, N,N,N-Trimethyloctan-1-aminium chloride for your process needs.Find product specific information including 10108-86-8 MSDS,Price,Custom Synthesis.
1H-Indol-5-aminium,N,N,N-trimethyl-(9ci)/ACM46190094 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
You are viewing an interactive 3D depiction of the molecule n,n,n-trimethyl-4-(2-oxo-1-pyrrolidinyl)-2-butyn-1-aminium (C11H20N2O) from the PQR.
A microsomal cytochrome P-450 (heme-thiolate) protein that catalyses two independent reactions at the same active site - the 17-hydroxylation of pregnenolone and progeste
A heme-thiolate protein (cytochrome P-450). The reaction proceeds in three stages, with two hydroxylations at C-22 and C-20 preceding scission of the side-chain between carbons 20 and 22. The initial source of the electrons is NADPH, which transfers the electrons to the adrenodoxin via EC 1.18.1.6, adrenodoxin-NADP+ reductase ...
Kallstenius Symphonie n 1 - Sinfonietta n 2 - Musica Sinfonica. Beermann., CPO777361, CPO, Classical, Our Labels, by CPO, Edvin Kallstenius 1881-1967 Symphonie n 1, op. 16 Sinfonietta n 2, op. 34 Musica Sinfonica, op. 42 Orchestre Symphonique de Helsin...
Stonans Ilmars; Dambrova Maija; Liepins Edgars; Kalvins Ivars; Lola Daina; Kuka Janis; Pugovics Osvalds; Vilskersts Reinis; Grinberga Solveiga; Loza Einars. Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular .... TN2013000404, 30.03.2015 ...
101-61-1 4,4-methylenebis(N,N-dimethylaniline) testing. Laboratory testing for CAS number 101-61-1. Aniline, 4,4-methylenebis[N,N-dimethyl-;Arnolds base;p,p-Bis(dimethylamino)diphenylmethane;4,4-Bis(dimethylamino)diphenylmethane;Bis[p-(N,N-dimethylamino)phenyl]methane;Bis[p-(dimethylamino)phenyl]methane;Bis[4-(dimethylamino)phenyl]methane;Bis[4-(N,N-dimethylamino)phenyl]methane;4,4-Bis(dimethylaminophenyl)methane;4,4-Methylenebis[N,N-dimethylaniline];Michlers base;Michlers hydride;Michlers methane;Reduced michlerS ketone;Tetrabase;Tet. This chemical is yellow to tan crystals
A novel approach for lignin and hexenuronic acid (HexA) removal from cellulosic pulp based on the combination of a vanadium haloperoxidase (Hap) and the tertiary amine 1,4-diazabicyclo[2.2.2]octane (DABCO) as a co-catalyst was tested on oxygen-delignified kraft pulp. It was found that the addition of DABCO, likely
Hazards: Bromine is corrosive and toxic.. Carbon tetrachloride is a cancer suspect agent. Toluene is flammable and toxic. Chemicals and Solutions: Materials: Two vials of toluene (about 10 ml each). 5% bromine in carbon tetrachloride solution. Plastic eyedropper Procedure: Add a few drops of the bromine solution rapidly to each of the vials of toluene. Show the class the orange solution produced. Place one of the vials on the overhead projector and watch this solution decolorize rapidly. The vial not placed on the overhead will decolorize much more slowly. This demo can be scaled up to be done in small hydrometer cylinders. Students will be able to see the the bromine fading out starting from the bottom and moving up the cylinder. Hint: Discussion: The halogenation reaction is a substitution reaction that takes place by a free radical mechanism.. ...
Autori: Silaghi-Dumitrescu, Radu. Editorial: European Journal of Inorganic Chemistry, p.1048-1052, 2003.. Rezumat:. Cuvinte cheie: P450, nitric oxide reductase, heme, push effect, thiolate obstruction, nitric oxide, hyponitrite. ...
3-((aminopropyl)amino)-N,N-dimethyl-N-(2-((4-(butylamino)benzoyl)oxy)ethyl)propan-1-aminium: a cyclic nucleotide-gated channel blocker; structure in first source
Cytochrome p450s comprise a superfamily of heme-thiolate proteins named for the spectral absorbance peak of their carbon-monoxide-bound species at 450 nm. Having been found in every class of organism, including Archaea, the p450 superfamily is believed to have originated from an ancestral gene that existed over 3 billion years ago. Repeated gene duplications have subsequently given rise to one of the largest of multigene families. These enzymes are notable both for the diversity of reactions that they catalyze and the range of chemically dissimilar substrates upon which they act. Cytochrome p450s support the oxidative, peroxidative and reductive metabolism of such endogenous and xenobiotic substrates as environmental pollutants, agrochemicals, plant allelochemicals, steroids, prostaglandins and fatty acids.
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Burkholderia pyrrocinia (Imanaka, Kousaka, Tamura and Arima 1965) Vandamme, Holmes, Vancanneyt, Coenye, Hoste, Coopman, Revets, Lauwers, Gillis, Kersters and Govan 1997 ...
College of Psychologists of Ontario , PAR Pre Review Questionnaire (Word) , https://cpo.on.ca/cpo_resources/par-pre-review-questionnaire-word/ ...
Weʼre raising money to Continue to fund the Association of Millwall Supporters & Millwall FC fight against Lewisham councils CPO plans for the land around The Den. Support this JustGiving Crowdfunding Page.
WALMSLEY, Ryan S. e TSHENTU, Zenixole R.. Imidazole-based vanadium complexes as haloperoxidase models for oxidation reactions. S.Afr.j.chem. (Online) [online]. 2010, vol.63, pp.95-104. ISSN 1996-840X.. Four imidazole-bound oxovanadium(IV) haloperoxidase model complexes were prepared. Two heterogeneous catalysts were prepared by first linking imidazole-4-carboxylic acid or 1-methylimidazole-2-carboxylic acid to chloromethylated polystyrene and subsequently reacting these polymer-anchored ligands with vanadyl sulphate. Two homogeneous catalysts were prepared by reaction vanadyl sulphate with the free ligands. The activity of the catalysts was evaluated for the hydrogen peroxide facilitated oxidation of styrene and ethylbenzene and thioanisole. A maximum conversion of 99.9 % for styrene and 10.6 % for ethylbenzene was achieved. Excellent conversions of thioanisole (100 %) were obtained under mild room temperature conditions. The heterogeneous catalysts also proved to be recyclable for this ...
There is researched the process of low-temperature decomposition of vanadium-containing titanomagnetite in a non-aqueous solvent environment in the following system: monoatomic aliphatic alcohol ROH (R = C7–C8) — mineral acid (HCl). The process of titanomagnetite decomposition by a non-aqueous solvent is found to be affected by the aliphatic alcohol structure, acid concentration in the extract, and the non-aqueous phase and solid phase ratio. According to the influence efficiency on titanomagnetite, the researched alcohols are different in the following range: n-heptanol > n-octanol > iso-octanol. This correlates with the alcohols’ dielectric constant. During the titanomagnetite decomposition process in a non-aqueous environment, it is found that ferrous iron chloride and vanadium are concentrated in the one phase, ferric iron chloride — in the extract, and titanium — in the hardly decomposable mineral part. The stability of non-aqueous solvent in time has been
A simple, sensitive and rapid spectrophotometric method for the determination of anions, nitrite and nitrate has been described. Determination of nitrite is by means of reactions involving tetrazotisation of Benzidine, followed by coupling withN,N-dimethylaniline and determination of nitrate is mainly based on reduction of nitrate to nitrite by using granular Zinc in NaCl. The produced nitrite is then availed to tetrazotize the Benzidine, which is then coupled with N,N-dimethylaniline to form pinkish red colored an azo dye in acidic medium. Measured the absorbance of resulted colored dye solution at 538 nm. Amount of reagents required is optimised and the extent of tolerance limit by the diverse ions was investigated. The Beer-Lambert s linearity range for Benzidine- N,N-dimethylaniline couple was found to be 0.05 to 0.3g/mL of nitrite with molar absorptivity 3.475x10Lmol-1cm-1 and sandell s sensitivity 3.3152x10-4gcm-2. The evaluated detection limit and quantization limit for the determination ...
Halogenated monoterpene production by the red macroalga Octhodes secundiramea was studied-under different levels of nutrient, bromide, vanadium and light delivery. The key products formed were identified as myrcene, betaelemene, the Z and E isomers of l0-bromomyrcene, 3-chloro-10E-bromomyrcene, Apakaocthodene A, and isomers of chloromyrcene and dibromomyrcene. The proposed pathway begins with an initial halogenation of myrcene to 3- chloromyrcene or 10-bromomyrcene. 10-bromomyrcene reacts with either chloride or bromide ions producing either 3-chloro-10E-bromomyrcene or 1,10- dibromomyrcene. The production of Apakaochtodene A starts from myrcene with 4 consecutive halogenation reactions, the first one forming the cyclic ring. All fermentations were carried out in similar 2L photobioreactors. Temperature was controlled at 26°C, with a photoperiod of 14 hours on:10 hours off. Incident light intensity was 143 μE m⁻² s⁻¹ for nutrient, bromide and vanadium delivery cultivations and the mean ...
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Parkinsons disease is the second most prevalent aging-related neurodegenerative disorder. Cell death in the substantia nigra, a motor region of the nervous system, is the key factor for the emergence of motor deficits in patients, although its critical role in Parkinsons disease pathogenesis is put into question. Understanding Halogenation explores how halogenation stress could participate in neuronal damage of the nervous system and parkinsonian deficits.. Following this, new insights into the C-F bonding nature of graphite fluorides with different fluorine concentrations C4F, C2F and C1F are presented. They are based on recent data from bulk techniques, which are very sensitive to the atomic local and electronic structure and C hybridization such as X-ray Raman Scattering and Pair Distribution Function analysis.. Lastly, a novel bromine-containing Still-Gennari-type phosphonate reagent, methyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)-2-bromoacetate is designed, synthesized, and applied to ...
A halogenation is either a substitution reaction in which one or more hydrogen atoms in an organic compound is replaced by halogen atoms or an addition reaction that introduces two or more halogen atoms to an organic compound.. eg. 1:. ...
A heme-thiolate protein (P-450). The conversion of substrate into product involves the hydroxylation of the syn-methyl (C9), intramolecular cyclization to the hemiketal and dehydration to the furan [1]. This is the second cytochrome P-450-mediated step of monoterpene metabolism in peppermint, with the other step being catalysed by EC 1.14.13.47, (S)-limonene 3-monooxygenase [1 ...
1b) solavetivol + NADPH + H+ + O2 = solavetivone + NADP+ + 2 H2O. For diagram of reaction click here.. Glossary: ( )-premnaspirodiene = ( )-vetispiradiene. Other name(s): HPO; Hyoscymus muticus premnaspirodiene oxygenase. Systematic name: ( )-vetispiradiene,NADPH:oxygen 2α-oxidoreductase. Comments: A heme-thiolate protein (P-450). The enzyme from the plant Hyoscymus muticus also hydroxylates valencene at C-2 to give the α-hydroxy compound, nootkatol, and this is converted into nootkatone. 5-Epiaristolochene and epieremophilene are hydroxylated at C-2 to give a 2β-hydroxy derivative which is not further oxidized.. Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: References:. 1. Takahashi, S., Yeo, Y.S., Zhao, Y., OMaille, P.E., Greenhagen, B.T., Noel, J.P., Coates, R.M. and Chappell, J. Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates. J. Biol. ...
Looking for online definition of CPO deficiency in the Medical Dictionary? CPO deficiency explanation free. What is CPO deficiency? Meaning of CPO deficiency medical term. What does CPO deficiency mean?
Literature References: Prepn: Finger, J. Prakt. Chem. [2] 79, 493 (1909); Mayer, Ber. 47, 1161 (1914). Acute toxicity: G. Ya. Kelman et al., Kauch. Rezina 26(9), 28 (1967), C.A. 67, 120013m (1967). Review of carcinogenicity studies: IARC Monographs vol. 4, 65-71 (1974); of toxicology and human exposure: Toxicological Profile for 4,4¢-Methylenebis(2-chloroaniline) (PB95-100186, 1994) 146 p. ...
A study was conducted to quantitate tissue macromolecular adduct formation after induction of drug metabolizing enzymes or long term oral administration of 4,4-methylenebis(2-chloroaniline) (101144) (MOCA), a model aromatic amine, in the rat. Male Sprague-Dawley- rats were administered carbon-14 (C-14) labeled MOCA at 28.1 micromole/kilogram (micromol/kg) daily for up to 28 days either by gavage
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Ammonium is an important source of nitrogen for many plant and microbial species. The ammonium (more obscurely: aminium) cation is a positively charged polyatomic cation with the chemical formula NH4+. It is formed by the protonation of ammonia (NH3). Ammonium is also a general name for positively charged or protonated substituted amines and quaternary ammonium cations (NR4+), where one or more hydrogen atoms are replaced by organic radical groups (indicated by R ...
You are viewing an interactive 3D depiction of the molecule (9r,21r)-1-[(2r,3s,4r,5r)-5-(6-amino-9h-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydro-2-furanyl]-3,5,9,21-tetrahydroxy-n,n,n,8,8-pentamethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphadocosan-22-aminium 3,5-dioxide (C28H28N8O18P3S+) from the PQR.
The University of Minnesota is one of the most comprehensive public universities in the United States and ranks among the most prestigious. It is both the state land-grant university, with a strong tradition of education and public service, and the states primary research university, with faculty of national and international reputation.
A dynamic quality control conditional purchase offer (CPO) management system is disclosed for processing CPOs received from one or more buyers for a product. The dynamic quality control CPO management
Re: Certified Pool Operator (CPO) training -- What is not ta Remember to only believe ~ 1/2 (thatd be .5 in metric :lol: ) of what they told you was...
Coloured scanning electron micrograph (SEM) of Curvularia verruculosa - vegetative, septate, dematiaceous hyphae. Curvularia verruculosa is a filamentous hyphomycete fungus. It is a common mould that is a soil facultative pathogen of many plant species, especially in tropical regions. It can cause Curvularia leaf spot and also food spoilage in pineapple fruits. Curvularia verruculosa can also cause eumycotic mycetomas in animals. Curvularia species can be the causative agents of phaeohyphomycosis. In humans Curvularia can cause wound infection, mycetoma, onychomycosis, keratitis, allergic sinusitis, cerebral abscess, cerebritis, pneumonia, allergic bronchopulmonary disease, endocarditis, and peritonitis. Magnification: x320 when shortest axis printed at 25 millimetres. - Stock Image C032/3185
Rice (Oryza sativa L.) is the second most important food crop after maize in Tanzania. It faces many challenges like diseases, pests and physical damages, which reduce the seed quality. This article identified microorganisms and the district where they occurred. 13 fungal species comprising of 11 pathogenic and 2 saprophytic fungi were detected and the incidence level varied among sample. Mvomero District showed the highest incidence recorded (64.5%) for sample collected from Hembeti and Dakawa/Msufini villages. In Kilombero, the fungal specie which detected highest incidence was Fusarium equiseti (31%) followed by Fusarium moniliforme (28.5%). Verticillium cinnabarinum and Curvularia inaequalis had the least incidence of 1 and 1%, respectively. The study recommends that before planting season, seeds should be tested to minimize spread of fungal species.   Key words: Pathogens, quality declared seed (QDS), farmer saved
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Vanadium has been found to play a number of roles in biological systems. It is present in certain vanadium dependent haloperoxidase and nitrogenase enzymes. Many sea squirts accumulate vanadium in very high concentration, although the reason is not known. The Amanita muscaria mushrooms also accumulate vanadium in the form of a coordination complex called amavadin, whose function is also unknown. Finally, a number of vanadium complexes have been shown to alleviate many of the symptoms of diabetes in both in vitro and in vivo (in rats and mice) studies. These complexes are being studied as potential alternatives to insulin therapy.. Research in the Pecoraro group has concentrated primarily on designing spectroscopic and functional models for vanadium dependent haloperoxidases (VHPOs). VHPOs catalyze the 2-electron oxidation of a halide (X- = Cl-, Br-, or I-) by peroxide through a Lewis acid-promoted mechanism (as opposed to redox cycling at the vanadium center) as summarized in Scheme 1. A ...
Search our free-access database for a CRO / CDMO that can develop, synthesize and manufacture your active pharmaceutical ingredient using halogenation.
1c) N,N-dihydroxy-L-valine = (E)-2-methylpropanal oxime + CO2 + H2O. Other name(s): CYP79D1; CYP79D2. Systematic name: L-valine,[reduced NADPH hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating). Comments: A cytochrome P-450 (heme-thiolate) protein. This enzyme catalyses two successive N-hydroxylations of L-valine, the committed step in the biosynthesis of the cyanogenic glucoside linamarin in Manihot esculenta (cassava). The product of the two hydroxylations, N,N-dihydroxy-L-valine, is labile and undergoes dehydration and decarboxylation that produce the (E) isomer of the oxime. It is still not known whether the decarboxylation is spontaneous or catalysed by the enzyme. The enzyme can also accept L-isoleucine as substrate, with a lower activity. It is different from EC 1.14.14.39, isoleucine N-monooxygenase, which prefers L-isoleucine.. Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: References:. 1. Andersen, M.D., Busk, P.K., Svendsen, I. and Møller, ...
A cytochrome P-450 (heme-thiolate) protein found in plants. The rice enzyme channels flavanones to the biosynthesis of tricin O-linked conjugates. cf. EC 1.14.20.5, flavone synthase I ...
The applicability of air sampling methods for aniline (62533) to its substituted derivatives, o-toluidine (95534), N,N-dimethylaniline (121697), o-anisidine (90040), o-chloraniline (95512), and mixed xylidines, was investigated. Aniline air sampling employed a tube containing two 50 milligram sections of 45:60 mesh silica gel. The effectiveness of the first sorbent section was described by the qua
1,2-Didecanoyl-sn-glycero-3-phosphocholine ≥99% (TLC); CAS Number: 3436-44-0; Synonyms: Didecanoyllecithin,3-sn-Phosphatidylcholine, 1,2-didecanoyl,PC,PC(10:0/10:0),(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-(1-oxodecyl)oxy-3,5,9-trioxa-4-phosphanonadecan-1-aminium 4-oxide, inner salt,1,2-Dicaprinoyl-sn-glycero-3-phosphocholine,L-α-Phosphatidylcholine, didecanoyl; find Sigma-Aldrich-P7081 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich
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For example, although eosinophil peroxidase is able to oxidize chloride, it preferentially oxidizes bromide. The mammalian ... Horseradish peroxidase is also capable of oxidizing these substrates, but its heme is not covalently bound and becomes damaged ... Haloperoxidases are peroxidases that are able to mediate the oxidation of halides by hydrogen peroxide. Both halides and ... The Nernst equation shows that hydrogen peroxide can oxidize chloride (E°= 1.36 V), bromide (E°= 1.09 V) and iodide (E°= 0.536 ...
Hypobromite is produced via eosinophil peroxidase, an enzyme that can use chloride but preferentially uses bromide. Bromide ... see lithium chloride). Like lithium carbonate and lithium chloride, it was used as a treatment for bipolar disorder. It has ... of those in blood and are strongly influenced by the body's chloride intake and metabolism. Since bromide is still used in ... its relationship to levels of both chloride and total dissolved solids and the implications for water treatment, Chemosphere, ...
... chloride peroxidase MeSH D08.811.682.732.380 - cytochrome-c peroxidase MeSH D08.811.682.732.440 - eosinophil peroxidase MeSH ... iodide peroxidase MeSH D08.811.682.732.550 - lactoperoxidase MeSH D08.811.682.732.700 - peroxidase MeSH D08.811.682.810.567 - ... horseradish peroxidase MeSH D08.811.682.732.512.900 - wheat germ agglutinin-horseradish peroxidase conjugate MeSH D08.811. ... D08.811.682.732.500 - glutathione peroxidase MeSH D08.811.682.732.512 - ...
Chile Chloride peroxidase, an enzyme Classic Produktion Osnabrück, a German classical music record label Code of Openness, or ...
Eosinophil peroxidase is a haloperoxidase that preferentially uses bromide over chloride for this purpose, generating ... Conversely, the bromide ion is a weaker reducing agent than iodide, but a stronger one than chloride. These similarities led to ... Anhydrous hydrogen bromide is a poor solvent, only able to dissolve small molecular compounds such as nitrosyl chloride and ... For example, in the presence of hydrogen peroxide, H2O2, formed by the eosinophil, and either chloride or bromide ions, ...
Eosinophil peroxidase is a haloperoxidase that preferentially uses bromide over chloride for this purpose, generating ... Conversely, the bromide ion is a weaker reducing agent than iodide, but a stronger one than chloride.[16] These similarities ... For example, in the presence of hydrogen peroxide, H2O2, formed by the eosinophil, and either chloride or bromide ions, ... For example, vinyl bromide can be used in the production of polyethylene, polyvinyl chloride or polypropylene. Specific highly ...
Ascorbate peroxidase Chloride peroxidase Cytochrome c peroxidase Haloperoxidase Hemoprotein Immunoperoxidase Lactoperoxidase ... Haem-using haem peroxidase and the related animal heme-dependent peroxidases DyP-type peroxidase family Catalase some ... Peroxidases are sometimes used as histological markers. Cytochrome c peroxidase is used as a soluble, easily purified model for ... Peroxidases typically catalyze a reaction of the form: ROOR ′ + 2 e − electron donor + 2 H + → Peroxidase ROH + R ′ OH {\ ...
EPO can take chloride, bromide and iodide as substrates, as well as the pseudohalide thiocyanate (SCN−). However, the enzyme ... Eosinophil peroxidase is a heme peroxidase, its activities including the oxidation of halide ions to bacteriocidal reactive ... Eosinophil+peroxidase at the US National Library of Medicine Medical Subject Headings (MeSH) Eosinophil peroxidase on InterPro ... Eosinophil peroxidase can be found in the primary (azurophilic) granules of human and mammalian leukocytes. Peroxidase ...
For example, eosinophil peroxidase appears to prefer bromide over chloride, yet is not considered a bromoperoxidase because it ... Bromide peroxidase (EC 1.11.1.18, bromoperoxidase, haloperoxidase (ambiguous), eosinophil peroxidase) is a family of enzymes ... Bromo peroxidases of red and brown marine algae (Rhodophyta and Phaeophyta) contain vanadate (vanadium bromoperoxidase). ... CS1 maint: discouraged parameter (link) Bromide+peroxidase at the US National Library of Medicine Medical Subject Headings ( ...
... (EC 1.11.1.10) is a family of enzymes that catalyzes the chlorination of organic compounds. This enzyme ... Hager LP, Hollenberg PF, Rand-Meir T, Chiang R, Doubek D (1975). "Chemistry of peroxidase intermediates". Ann. N. Y. Acad. Sci ... This enzyme belongs to the family of oxidoreductases, specifically those acting on a peroxide as acceptors (peroxidases). The ... Poulos TL, Sundaramoorthy M, Terner J (1995). "The crystal structure of chloroperoxidase: a heme peroxidase--cytochrome P450 ...
These cells react the bromide with peroxide to generate hypobromite by the action of eosinophil peroxidase, a haloperoxidase ... enzyme which preferentially uses bromide over chloride for this purpose. Simple bromide salts (such as sodium bromide) are also ... in a similar fashion to the action of peroxidase on bromide in eosinophils. Hypobromite has been proposed to be a reactive ...
... (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene on chromosome 17. MPO is most abundantly ... and chloride anion (Cl−) (or hypobromous acid if Br- is present) during the neutrophil's respiratory burst. It requires heme as ... MPO is a member of the XPO subfamily of peroxidases and produces hypochlorous acid (HOCl) from hydrogen peroxide (H2O2) ...
If streptavidin-HRP (streptavidin and horseradish peroxidase conjugate) is used, then using TMB (tetramethylbenzidine) as a ... a mixture of 5-bromo-4-chloro-3-indolyl phosphate and nitroblue tetrazolium chloride) as a substrate will produce more distinct ...
Iodide then travels from within the cell into the lumen, through the action of pendrin, an iodide-chloride antiporter. In the ... Antibodies against thyroid peroxidase can be found on testing. The inflammation usually resolves without treatment, although ... and the iodine is attached to the active tyrosine units in thyroglobulin by the enzyme thyroid peroxidase. This forms the ...
The chlorides are obtained by chlorination of the selenenyl chloride. Seleniranes are three-membered rings (parent: C2H4Se) ... They occur in some selenoenzymes, such as glutathione peroxidase. Seleninic acids (RSe(O)OH) are analogues of sulfinic acids. ...
O2 and chloride, Cl−. Chlorite dismutase is a heme-containing protein, but it bears no structural or sequence relationships ... with known peroxidases or other heme proteins and is part of a large family of proteins with more than one biochemical function ...
... l is one important characteristic of animal peroxidases; plant peroxidases incorporate heme B. Lactoperoxidase and ... giving this enzyme the unique capability of easily oxidizing chloride and bromide ions to hypochlorite and hypobromite. ... In peroxidase reactions, the porphyrin molecule also serves as an electron source, being able to delocalize radical electrons ... Heme m contains the two ester bonds at the heme 1- and 5-methyl groups also present in heme l of other mammalian peroxidases, ...
Like horseradish peroxidase, lanthanum is used as an electron-dense tracer in molecular biology. Lanthanum-modified bentonite ( ... Lanthanum metal is obtained from its oxide by heating it with ammonium chloride or fluoride and hydrofluoric acid at 300-400 °C ... Cerium-doped lanthanum bromide and lanthanum chloride are the recent inorganic scintillators, which have a combination of high ... Various compounds of lanthanum and other rare-earth elements (oxides, chlorides, etc.) are components of various catalysis, ...
Bahadur also reported having detected ATPase-like and peroxidase-like activity. Bahadur stated that by using molybdenum as a ... Inorganic substances such as colloidal ferric chloride or molybdenum compounds supposedly acted as cofactors and catalysts. ... colloidal molybdenum oxide or potassium nitrate and ferric chloride under sunlight. It appears that this experimental approach ...
In the colloid, iodide (I−) is oxidized to iodine (I0) by an enzyme called thyroid peroxidase. - Iodine (I0) is very reactive ... an iodide-chloride antiporter. In the follicular space, the iodide is then oxidized to iodine. This makes it more reactive,[32] ... Antibodies against thyroid peroxidase can be found on testing. The inflammation usually resolves without treatment, although ... and the iodine is attached to the active tyrosine units in thyroglobulin by the enzyme thyroid peroxidase. This forms the ...
For bis(trifluoromethyl)peroxide this will be the following reaction: Peroxidase + C2F6O2 → 2CF3O- The peroxidase will then ... The deactivation is carried out by adding anhydrous calcium chloride to the mixture. The deactivated mixture is scrubbed with ... These pathways make use of different enzymes, but of the same sort, peroxidases. The phase 1 metabolism of peroxides is an ...
It is also on the list in combination with sodium chloride. The name glucose derives through the French from the Greek γλυκός ... Another enzyme, peroxidase, catalyzes a chromogenic reaction (Trinder reaction) of phenol with 4-aminoantipyrine to a purple ... Glucose forms a black mass with stannous chloride. In an ammoniacal silver solution, glucose (as well as lactose and dextrin) ... "Dextrose mixture with sodium chloride". Drug Information Portal. U.S. National Library of Medicine. Chemistry portal Medicine ...
In research, this reaction is used to stain cells that were prepared with hydrogen peroxidase enzyme, following common ... chloride instead of iron powder or with sodium dithionite in methanol. In its main application, DAB is the precursor to ... One other method uses complexes of injected biocytin with avidin or streptavidin, biotin, and then peroxidase. Hans Schwenecke ... which is conjugated with a peroxidase enzyme. This will bind DAB as a substrate and oxidize it, producing an easily observable ...
Upon heating, hypochlorite degrades to a mixture of chloride, oxygen, and chlorates: 2 ClO− → 2 Cl− + O 2 3 ClO− → 2 Cl− + ClO ... "New and classic families of secreted fungal heme peroxidases". Appl Microbiol Biotechnol. 87 (3): 871-897. doi:10.1007/s00253- ... This enzyme combines the inorganic substrates chloride and hydrogen peroxide to produce the equivalent of Cl+, which replaces a ... Thomas, E. L. (1979). "Myeloperoxidase, hydrogen peroxide, chloride antimicrobial system: Nitrogen-chlorine derivatives of ...
Second, the horseradish peroxidase utilizes the hydrogen peroxide to oxidize ABTS to its radical cationic form, ABTS+•. As the ... Another formula consists of indigo carmine, dye, ascorbic acid (Vitamin C), sodium bicarbonate, sodium chloride, copper(II) ... The experiment is performed in a clear glass vial containing two common enzymes (glucose oxidase and horseradish peroxidase), ...
It acts as a mimic of glutathione peroxidase and can also react with peroxynitrite. It is being investigated as a possible ... benzoyl chloride (Route I), by ortho-lithiation of benzanilides followed by oxidative cyclization (Route II) mediated by cupric ... "Ebselen treatment reduces noise induced hearing loss via the mimicry and induction of glutathione peroxidase". Hearing Research ...
Most iodide salts are soluble in water, but often less so than the related chlorides and bromides. Iodide, being large, is less ... peroxidase + H2O2 + tyrosine, histidine, lipid, etc. → iodo-compounds + H2O + 2 e− (antioxidants). Iodargyrite-natural, ... One consequence of this is that sodium iodide is highly soluble in acetone, whereas sodium chloride is not. The low solubility ... For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In ...
... dimethylarsenic chloride. Some were employed as chemical warfare agents, especially in World War I. This threat led to many ... that take place which may increase the toxicity of arsenic due to MMeAsIII being a potent inhibitor of glutathione peroxidase, ...
Chlorine as chloride ions; very common electrolyte; see sodium, below. Magnesium, required for processing ATP and related ... Molybdenum required for xanthine oxidase and related oxidases Selenium required for peroxidase (antioxidant proteins) Zinc ... typically as sodium chloride (salt). Excessive sodium consumption can deplete calcium and magnesium. Sodium has a role in the ...
These systems include peroxidases, catalases, and superoxide dismutases. A complementary metalloprotein to those that react ... The most important ions are sodium, potassium, calcium, magnesium, chloride, phosphate, and bicarbonate. The maintenance of ...
Table salt (sodium chloride) is the main dietary source. hypochloremia hyperchloremia Sodium 01500.0001500 2300; NE Quantity A ... Essential to activity of antioxidant enzymes like glutathione peroxidase Brazil nuts, seafoods, organ meats, meats, grains, ... Table salt (sodium chloride, the main source), sea vegetables, milk, and spinach. hyponatremia hypernatremia ...
Peroxidase. References[edit]. *^ a b PDB: 1VAR​; Borgstahl GE, Parge HE, Hickey MJ, Johnson MJ, Boissinot M, Hallewell RA, ... "Mechanism and thermodynamics of guanidinium chloride-induced denaturation of ALS-associated mutant Cu,Zn superoxide dismutases ...
Banerjee, R. K.; Datta, A. G. (1986). "Salivary peroxidases". Mol Cell Biochem. 70 (1): 21-29. doi:10.1007/bf00233801. PMID ... 5-40 mmol/L chloride (lower than plasma). *25 mmol/L bicarbonate (higher than plasma) ... Banerjee, R. K.; Bose, A. K.; Chakraborty, T. K.; De, S. K.; Datta, A. G. (1985). "Peroxidase-catalysed iodotyrosine formation ... lysozyme and peroxidase.[15] It has not been shown that human licking of wounds disinfects them, but licking is likely to help ...
... may even deal with detoxification of chlorinated materials in a way analogous to heme-containing P450 enzymes and peroxidases. ... Nitro blue tetrazolium chloride test. *Complete blood count *Absolute neutrophil count. Other. *Blood film *Leucoerythroblastic ...
"Selenium : Selenium(I) chloride compound data"। WebElements.com। সংগ্রহের তারিখ ২০০৭-১২-১০।. উদ্ধৃতি টেমপ্লেট ইংরেজি ... Kraus, R. J.; Prohaska, J. R.; Ganther, H. E. (১৯৮০)। "Oxidized forms of ovine erythrocyte glutathione peroxidase. Cyanide ... Heinz, G. H.; Hoffman, D. J. (১৯৯৮)। "Methylmercury chloride and selenomethionine interactions on health and reproduction in ...
HpODE is rapidly reduced by peroxidases to 13(S)-HODE.[1][5] ALOX15 is fully capable of metabolizing the linoleic acid that is ... Phenacyl chloride. *Polygodial (Dorrigo pepper). *Shogaols (ginger, Sichuan and melegueta peppers). *Tear gases ...
Chloride; electrolyte; see sodium, below. *Magnesium, required for processing ATP and related reactions (builds bone, ... Selenium required for peroxidase (antioxidant proteins). *Zinc required for several enzymes such as carboxypeptidase, liver ... Sodium, an electrolyte; common in food and manufactured beverages, typically as sodium chloride. Excessive sodium consumption ...
Chlorine as chloride ions; very common electrolyte; see sodium, below.. *Magnesium, required for processing ATP and related ... Selenium required for peroxidase (antioxidant proteins). *Zinc required for several enzymes such as carboxypeptidase, liver ... typically as sodium chloride, or common salt. ...
... peroxidase} }}\mathrm {H_{2}O} +\mathrm {oxidized\ chromogen} }. Inhibited by reducing substances like BUA, bilirubin, ...
These chemists optimized a route beginning with the O-benzoylation of p-hydroxy-phenacyl chloride, followed by reaction of the ... and in the activity of glutathione peroxidase (GPx).[87] ... resulting O-protected chloride with N-methyl-benzylamine to ...
... l is one important characteristic of animal peroxidases; plant peroxidases incorporate heme B. Lactoperoxidase and ... giving this enzyme the unique capability of easily oxidizing chloride and bromide ions. Myeloperoxidase is present in mammalian ... In peroxidase reactions, the porphyrin molecule also serves as an electron source. In the transportation or detection of ... Heme l is the derivative of heme B which is covalently attached to the protein of lactoperoxidase, eosinophil peroxidase, and ...
Results are typically expressed as gallic acid equivalents (GAE). Ferric chloride (FeCl3) test is also a colorimetric assay. ... glutathione S-transferase and glutathione peroxidase can be monitored. A prophenoloxidase can also be recovered from the insect ...
... the presence of catalase or other peroxidases in these organisms can increase tolerance in the presence of lower concentrations ... chlorine/chloride 1.4 In acidic solutions Fe2+. is oxidized to Fe3+. (hydrogen peroxide acting as an oxidizing agent): ...
... dimethylarsenic chloride. Some were employed as chemical warfare agents, especially in World War I. This threat led to many ... due to MMeAsIII being a potent inhibitor of glutathione peroxidase,[37] glutathione reductase, pyruvate dehydrogenase,[38] and ...
The most important ions are sodium, potassium, calcium, magnesium, chloride, phosphate and the organic ion bicarbonate. The ... damaging oxidants are removed by antioxidant metabolites such as glutathione and enzymes such as catalases and peroxidases. ...
NSDHL Chloride diarrhea, congenital, Finnish type; 214700; SLC26A3 Cholestasis, benign recurrent intrahepatic, 2; 605479; ... PRSS7 Eosinophil peroxidase deficiency; 261500; EPX Epidermodysplasia verruciformis; 226400; TMC6 Epidermodysplasia ... ATP2A1 Bronchiectasis with or without elevated sweat chloride 1; 211400; SCNN1B Bronchiectasis with or without elevated sweat ... chloride 2; 613021; SCNN1A Bronchiectasis with or without elevated sweat chloride 3; 613071; SCNN1G Brooke-Spiegler syndrome; ...
Salt-tolerant (moderately halophytic) barley and/or sugar beets are commonly used for the extraction of sodium chloride (common ... in plants enzymes such as peroxidases, phenoloxidases, esterases and nitroreductases carry out the same role. In the second ...
The only stable chloride is selenium monochloride (Se2Cl2), which might be better known as selenium(I) chloride; the ... One family of selenium-bearing molecules (the glutathione peroxidases) destroys peroxide and repairs damaged peroxidized cell ... such as glutathione peroxidases and certain forms of thioredoxin reductase found in animals and some plants (this enzyme occurs ... a dithiol that serves as an electron source for peroxidases and also the important reducing enzyme ribonucleotide reductase ...
Vegetable peroxidase and bacterial enzymes, including an Escherichia coli peroxidase, may also cause false-positive reactions. ... stannous chloride). On application of a drop of urine and heating over a candle the strip immediately turned black if the urine ... The urine test strip test for blood is based on hemoglobin's pseudo peroxidase activity in catalysing a reaction between ... A second linked reaction, mediated by a peroxidase, catalyses the reaction between the peroxide and a chromogen (a substance ...
Vinyl Chloride) (PVC) and Chlorinated Poly(Vinyl Chloride) (CPVC) D6264/D6264M - 17 Test Method for Measuring the Damage ... 20 Test Method for Determination of Hydrogen Peroxide and Combined Organic Peroxides in Atmospheric Water Samples by Peroxidase ... Vinyl Chloride) Insulation for Wire and Cable, 90°C Operation D6097 - 16 Test Method for Relative Resistance to Vented Water- ... Vinyl Chloride)(PVC) Siding D6778 - 20 Classification System and Basis for Specification for Polyoxymethylene Molding and ...
... stimulates the transcription of genes for aldose reductase (AR), the sodium chloride-betaine cotransporter (SLC6A12) the ... 2002). "The characterization and purification of a human transcription factor modulating the glutathione peroxidase gene in ...
Chloride peroxidase (EC 1.11.1.10) is a family of enzymes that catalyzes the chlorination of organic compounds. This enzyme ... Hager LP, Hollenberg PF, Rand-Meir T, Chiang R, Doubek D (1975). "Chemistry of peroxidase intermediates". Ann. N. Y. Acad. Sci ... This enzyme belongs to the family of oxidoreductases, specifically those acting on a peroxide as acceptors (peroxidases). The ... Poulos TL, Sundaramoorthy M, Terner J (1995). "The crystal structure of chloroperoxidase: a heme peroxidase--cytochrome P450 ...
The grade of cellular destruction caused by benzalkonium chloride was dependent upon the concentration and exposure time of the ... The present light and transmission electron microscopic study reveals that the cationic surfactant, benzalkonium chloride, ... A tight barrier against permeation of horseradish peroxidase into the corneal epithelium exists at the corneal surface adjacent ... PERMEABILITY OF RABBIT CORNEAL EPITHELIUM TO HORSERADISH PEROXIDASE AFTER THE INFLUENCE OF BENZALKONIUM CHLORIDE. ...
... horseradish peroxidase (HRP), or cobalt chloride. A small crystal of the stain reagent was applied directly onto the sensory ... Where cobalt chloride was used as a stain, the cobalt was precipitated by reaction with hydrogen sulfide, and then fixed with ... Cobalt chloride was especially useful because it often resulted in staining scores of afferents and this en masse staining of ... It was possible to make small lesions in the bulba and apply small amounts of marker reagents (such as cobalt chloride, HRP, ...
Chloride peroxidase activity. Specific Function. Not Available. Gene Name. cpo. Uniprot ID. O31168. Uniprot Name. Non-heme ... Benzoic Acid (0.2 %) + Benzethonium chloride (0.13 %) + Camphor (0.7 %) + Ethanol (40 %). Liquid. Topical. Mahdeen ...
Of particular interest are YisY, very likely to be a chloride peroxidase; CotQ, highly similar to reticuline oxidase from ... and the similarity of CotJC to peroxidase (70). Oxidases can participate in a wide variety of biosynthetic activities. ...
Effects of sample dilution, peroxidase concentration, and chloride ion on the measurement of unbound bilirubin in premature ... The peroxidase test, with a few modifications, has been used for many clinical and laboratory research studies.13,16.17,45,46, ... BFree measured by this method compares favorably with BFree determined by the peroxidase test,4 and the test has been used in 1 ... Two emerging tests that measure BBC5,6 and BFree4 overcome the practical limitations of the peroxidase test. Although these ...
For example, although eosinophil peroxidase is able to oxidize chloride, it preferentially oxidizes bromide. The mammalian ... Horseradish peroxidase is also capable of oxidizing these substrates, but its heme is not covalently bound and becomes damaged ... Haloperoxidases are peroxidases that are able to mediate the oxidation of halides by hydrogen peroxide. Both halides and ... The Nernst equation shows that hydrogen peroxide can oxidize chloride (E°= 1.36 V), bromide (E°= 1.09 V) and iodide (E°= 0.536 ...
... glutathione peroxidase (GSH-PX); 2,3,5-triphenyltetrazolium chloride (TTC); subcutaneously (s.c.); ischemia-reperfusion (IR); ... and glutathione peroxidase (GSH-Px), and antioxidant glutathione (GSH), cut down malondialdehyde (MDA) and reactive oxygen ... glutathione peroxidase (GSH-Px); glial cell-derived neurotrophic factor (GDNF).. ...
... peroxidase substrate) containing nickel chloride as an enhancing reagent. The reaction was terminated by washing twice in water ... Sections were washed in PBS and incubated for 10 min in 0.1% H2O2 to block endogenous peroxidase activity. After washing in PBS ...
CHLORIDE ION. Cl. VEXZGXHMUGYJMC-UHFFFAOYSA-M. Ligand Interaction. OXY. Query on OXY. Download CCD File A, B ... Catalase-peroxidase. A, B. 728. Burkholderia pseudomallei 1710b. Mutation(s): 0 Gene Names: katG, BURPS1710b_3366. EC: 1.11. ... The Catalase Activity of Catalase-Peroxidases Is Modulated by Changes in the pKa of the Distal Histidine.. Machuqueiro, M., ... Crystal structure of the V293D variant of catalase-peroxidase from B. pseudomallei. *DOI: 10.2210/pdb5KQH/pdb ...
... chloride ester alkaline peroxidase 4-Cl--1- 4-Cl--1- 1. 4-Cl--1-naphthyl phosphate → 4-Cl--1-naphthol phosphatase naphthyl ... For example, by having glucose oxidase and horse radish peroxidase on the surface, with catalase bound to a mip, the more ... The following abbreviations are employed: CMM--O3 -carboxymethyl morphine; HRP--horse radish peroxidase; NHS--N-hydroxy ... peroxidase dye 2. H.sub.2 O.sub.2 + -o-dianisidine → dye glucose microper- β-D-glucose bis-toluidine 1. glucose + O.sub.2 → D- ...
... succinyl chloride, glutaryl chloride, and lauryl chloride. These chemicals are available from Aldrich Chemical Company ( ... sodium bisulfite and oxidative enzymes such as peroxidase or catechol oxidase. When initiators are employed, polymerization ... succinyl chloride, glutaryl chloride, lauryl chloride, or a combination of the foregoing. ... succinyl chloride, glutaryl chloride, lauryl chloride, or a combination of the foregoing. ...
rhb:NY08_4709 chloride peroxidase 293 113 ( 12) 32 0.400 90 -, 2 rpf:Rpic12D_4248 TonB-dependent receptor K02014 772 113 ( -) ... psm:PSM_A0834 voltage-gated ClC-type chloride channel c 560 100 ( -) 29 0.342 76 -, 1 pstw:DSJ_24400 hypothetical protein 423 ... pia:PI2015_0815 Voltage-gated ClC-type chloride channel 560 100 ( -) 29 0.342 76 -, 1 pmv:PMCN06_1227 thymidylate synthase ... plz:S4054249_04935 voltage-gated chloride channel 560 105 ( -) 30 0.351 77 -, 1 psos:POS17_4277 peptide synthase 4338 105 ( -) ...
Buy our Recombinant Human Glutathione Peroxidase 1 protein. Ab109344 is a protein fragment produced in Escherichia coli and has ... Constituents: 0.0154% DTT, 0.869% Tris HCl, 0.87% Sodium chloride. * Reconstitution. Reconstitute with water,recommended 10µl ( ... Recombinant Human Glutathione Peroxidase 1 protein. See all Glutathione Peroxidase 1 proteins and peptides. ...
The peroxidase activity was developed with freshly prepared DAB (0.025%), nickel chloride (0.02%), and hydrogen peroxide (0.005 ... The slides were washed with 0.3% hydrogen peroxide in methanol for 15 min to remove endogenous peroxidase and immersed in 1% ... After extensive washing, avidin-biotin-peroxidase complex (Vector Laboratories) was applied for 30 min. ...
The assay was terminated by second anti-body labeling with donkey anti-goat IgG conjugated to horseradish peroxidase antiserum ... methylene chloride, ethyl acetate, chloroform, acetone, benzene, 2-butanone, carbon tetrachloride, chloroform, n-heptane, n- ... A 3,3-diaminobenzidine (DAB) substrate kit for peroxidase (Vector laboratories, Burlingame Calif.) was used supplemented with ... nickel chloride to develop the staining. FIG. 13. shows an osteocalcin-labeled scaffold seeded with Dex+ cells and maintained ...
Standard peroxidase enzyme substrate, 3,3′-diaminobenzidine (Sigma) with nickel chloride (Sigma) then was added to yield a ... In theory, the application of H2O2 to block endogenous peroxidase could artifactually induce the formation of epitopes ... A biotin-labeled anti-mouse secondary antibody then was applied for 30 minutes, followed by an avidin-biotin-peroxidase ... The wells were rinsed five times with PBS; 200 μL of horseradish peroxidase-conjugated anti-mouse antibody (Boehringer Mannheim ...
Mouse monoclonal Glutathione Peroxidase 4 antibody [1H11] validated for IP, ELISA and tested in Human, Mouse and Rat. Immunogen ... Constituents: HEPES, 50% Glycerol, 0.87% Sodium chloride, 0.01% BSA. * Concentration information loading... ... Anti-Glutathione Peroxidase 4 antibody [1H11]. See all Glutathione Peroxidase 4 primary antibodies. ... Phospholipid hydroperoxide glutathione peroxidase antibody. *Phospholipid hydroperoxide glutathione peroxidase mitochondrial ...
... chloride; GM, Gastric mucosa; GPx, Glutathione peroxidase; GSH, Glutathione; GSR, Glutathione-disulfide reductase; H2S, ... 0,1 ml post-nuclear homogenates of the stomach (1:4 w/v in 1,15% Potassium chloride solution) were added to 0.5 ml incubation ... The stomach was washed with cold 1.15% potassium chloride solution, after which the mucous membrane was separated and ... Hydrogen chloride; HFD, High fructose diet; K+ ATP-channels, Adenosine triphosphate-sensitive potassium channels; MPTP, ...
Zinc Chloride also improved kidney function as determined by the restoration of blood urea and creatinine level. Finally, Zinc ... Results showed that Zinc Chloride was able to control STZ-induced DN in rats as it normalized the elevated blood pressure, the ... These results suggest that exposure to Zinc Chloride can protect from diabetic nephropathy and can be used as an adjuvant ... This study was conducted to investigate the effect of Zinc Chloride on streptozotocin-induced diabetic nephropathy in rats ...
Permeability of rabbit corneal epithelium to horseradish peroxidase after the influence of benzalkonium chloride. Acta ... Graf P. Benzalkonium chloride as a preservative in nasal solutions: re-examining the data. Respir Med 2001; 95: 728-33PubMed ... Graf P, Enerdal J, Hallén H. Ten days use of oxymetazoline nasal spray with or without benzalkonium chloride in patients with ... Hallén H, Graf P. Benzalkonium chloride in nasal decongestive sprays has a long-lasting adverse effect on the nasal mucosa of ...
Thomas, E. L., and Fishman, M. (1986). Oxidation of chloride and thiocyanate by isolated leukocytes. J. Biol. Chem. 261, 9694- ... The complete antimicrobial peroxidase system requires three components: a particular peroxidase enzyme, hydrogen peroxide (H2O2 ... Peroxidases alone have no antibacterial effect. However, a peroxidase exerts an antimicrobial effect indirectly by catalyzing ... and does not employ a peroxidase enzyme. Indeed, though the literature indicates that the peroxidase enzyme is required to ...
Synthesis of partly debranched starch-g-poly(2-acryloyloxyethyl trimethyl ammonium chloride) catalyzed by horseradish ... peroxidase and the effect on adhesion to polyester/cotton yarn. Publication date: Available online 20 July 2020Source: Process ...
chloride peroxidase. environmental protection. this enzyme may by employed to treat contaminated soil or water prior to ... lignin peroxidase enzyme production using sewage treatment plant sludge as a major substrate seems to be a promising and ... a high and sustainable lignin peroxidase activity is achieved via in situ release of H2O2 by a co-immobilized glucose oxidase. ... use of Phanerochaete chrysosporium and its enzyme lignin peroxidase in the degradation of environmental pollutants such as dye ...
1% Nickel Chloride (20x) in Distilled Water: Add 0.1g of nickel chloride in 10 ml distilled water. Shake to dissolve. Store at ... 0.05% DAB, 0.05% Nickel Chloride and 0.015% H2O2 in PBS, pH7.2. (pH value is important! pH , 7.0 will reduce staining intensity ...
... glutathione peroxidase (GPx), glutathione-s-transferase (GST), protein kinase C (PKC), Na(+), K(+)-adenosine triphosphatase (Na ... Chlorides / toxicity* * Curcumin / pharmacology* * Glutathione Peroxidase / metabolism * Glutathione Transferase / metabolism * ... glutathione peroxidase (GPx), glutathione-s-transferase (GST), protein kinase C (PKC), Na(+), K(+)-adenosine triphosphatase (Na ...
... methyl chloride; methylene chloride; peroxidase; polyphenols; roots; solvents; superoxide dismutase. Abstract:. ... The effects ... peroxidase; plant growth; polyphenols; seedlings; soil water; water stress. Abstract:. ... This study investigated the effects ...
Displays glutathione peroxidase activity with cumene hydroperoxide. Gene Name:. GSTT1. Uniprot ID:. P30711 Molecular weight:. ... The amount of chloride in the blood is carefully controlled by the kidneys. Chloride ions have important physiological roles. ... In nature, chlorine is most abundant as a chloride ion. Physiologically, it exists as an ion in the body. The chloride ion is ... Also, the chloride-bicarbonate exchanger biological transport protein relies on the chloride ion to increase the bloods ...
Immunoperoxidase staining was performed with a Vectastain avidin-biotin peroxidase kit (Vector Laboratories) using ... diaminobenzidine and nickel (II) chloride to give black staining (37). Staining patterns observed with patient IgG were ... acetone-fixed human brain sections containing both white and gray matter using biotinylated Abs detected with avidin-peroxidase ...
Effect of hexaammineruthenium chloride and/or horseradish peroxidase on the performance of hydrogen peroxide (bio)sensors: a ...
  • The catalytic acid base, required to cleave the peroxide O-O bond, is glutamic acid rather than histidine as in horseradish peroxidase. (wikipedia.org)
  • A tight barrier against permeation of horseradish peroxidase into the corneal epithelium exists at the corneal surface adjacent to the tear film. (scite.ai)
  • Horseradish peroxidase is also capable of oxidizing these substrates, but its heme is not covalently bound and becomes damaged during turnover. (wikipedia.org)
  • Immobilization of horseradish peroxidase on PMMA nanofibers incorporated with nanodiamond. (sparrho.com)
  • In the present study, nanodiamond (ND) was blended with polymethyl methacrylate (PMMA) and then electrospun into nanofibers (nfPMMA-ND) for the immobilization of horseradish peroxidase (HRP). (sparrho.com)
  • Horseradish peroxidase and chitosan: activation, immobilization and comparative results. (sparrho.com)
  • The distribution of sodium, choline, sulfate, and chloride ions around two proteins, horseradish peroxidase (HRP) and bovine pancreatic trypsin inhibitor (BPTI), is investigated by means of molecular dynamics simulations with the aim to elucidate ion adsorption at the protein surface. (uni-regensburg.de)
  • Peroxidase-conjugated goat igg fraction to rabbit IgG (whole molecule) is the lyophilized powder of horseradish peroxidase (HRP)-conjugated goat IgG fraction to rabbit IgG (whole molecule) and buffer salts. (mpbio.com)
  • The heme-containing chloroperoxidase (CPO) exhibits peroxidase, catalase and cytochrome P450-like activities in addition to catalyzing halogenation reactions. (wikipedia.org)
  • The unusual Met-Tyr-Trp adduct composed of cross-linked side chains along with an associated mobile Arg is essential for catalase activity in catalase-peroxidases. (rcsb.org)
  • Muscle viability (evaluated by triphenyltetrazolium chloride dye method), malondialdehyde, superoxide dismutase, catalase, and glutathione peroxidase were assessed in muscle samples using a spectrophotometer. (readbyqxmd.com)
  • Glutathione peroxidase and catalase activities were enhanced, while superoxide dismutase activity was depressed in HgCl(2)-treated rats when compared to control and these effects were prevented by ASX. (unboundmedicine.com)
  • We measured the levels of Cd, lipid peroxidation (LPO), nitric oxide, glutathione (GSH), and oxidative enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase, and glutathione reductase (GR) in the whole brain homogenate. (bioscirep.org)
  • 12. The collagen composition of claim 1 wherein the composition is polymerizable by exposing to UV and an initiator selected from the group comprising sodium persulfate, sodium thiosulfate, ferrous chloride tetrahydrate, sodium bisulfite or a combination of the foregoing. (google.com.au)
  • Cystic fibrosis (CF) is caused by alterations in the CF transmembrane conductance regulator (CFTCR) gene that result in deranged sodium and chloride ion transport channels. (hmdb.ca)
  • Sulfate is always strongly attached to the proteins, choline shows a significant, but unspecific, propensity for the protein surfaces, and sodium ions have a weak surface affinity, while chloride has virtually no preference for the protein surface. (uni-regensburg.de)
  • In mixtures of all four ion species in protein solutions, the resulting distributions are almost a superposition of the distributions of sodium sulfate and choline chloride, except that sodium partially replaces choline close to the proteins. (uni-regensburg.de)
  • The product is dialyzed into 0.02M sodium phosphate, 0.14M sodium chloride, pH 7.3, adjusted to standard titer, filtered through a 0.22 µm filter, vialed and lyophilized. (mpbio.com)
  • sodium chloride salt concentration, the amount of green weight, dry weight increase ALW specific leaf weight and leaf area was increased as well. (gasemie-ilkhichi.ir)
  • Chloride peroxidase (EC 1.11.1.10) is a family of enzymes that catalyzes the chlorination of organic compounds. (wikipedia.org)
  • It differs from EC 1.11.1.10 chloride peroxidase in its preference for formation of hypochlorite over the chlorination of organic substrates under physiological conditions (pH 5-8). (qmul.ac.uk)
  • In recent years, the synergistic relationship between NADPH oxidase (NOX)/dual oxidase (DUOX) enzymes and peroxidases has received increased attention. (genetics.org)
  • These enzymes generate the H 2 O 2 required as substrate for the peroxidases. (genetics.org)
  • Thus, glutathione peroxidase (GPx) is one of the enzymes, selenium-dependent type, which is involved on the transformation of reactive oxygen species, catalyzing the reduction of hydrogen peroxide (H 2 O 2 ) or lipoperoxide (L-OOH), using GSH as a reducing agent 5, 6 . (scielo.cl)
  • While the expression of brain SOD2 , CAT, glutathione peroxidase 1, and GR was down-regulated in the Cd-treated group, the expression of these enzymes was up-regulated in rats pretreated with SME. (bioscirep.org)
  • This enzyme combines the inorganic substrates chloride and hydrogen peroxide to produce the equivalent of Cl+, which replaces a proton in hydrocarbon substrate: R-H + Cl− + H2O2 + H+ → R-Cl + 2 H2O In fact the source of "Cl+" is hypochlorous acid (HOCl). (wikipedia.org)
  • This enzyme belongs to the family of oxidoreductases, specifically those acting on a peroxide as acceptors (peroxidases). (wikipedia.org)
  • The systematic name of this enzyme class is chloride:hydrogen-peroxide oxidoreductase. (wikipedia.org)
  • A process for the preparation of a phenolic resin which comprises reacting a phenol with a peroxidase or an oxidase enzyme and a peroxide in an organic solvent containing medium to generate phenolic radicals which react to form a phenolic resin. (freepatentsonline.com)
  • 3. The process of claim 2 wherein said enzyme is a peroxidase enzyme. (freepatentsonline.com)
  • Glucose electrodes were coated with an oxidizing enzyme (peroxidase) which allows hydrogen peroxide to selectively oxidize ascorbate, urate, bilirubin, and acetaminophenol in the presence of glucose. (google.com.au)
  • 3. The biosensor of claim 2, wherein the enzyme is peroxidase. (google.com.au)
  • An enzyme that catalyzes the chlorination of a range of organic molecules, forming stable carbon-chloride bonds. (bvsalud.org)
  • Peroxidase-conjugated goat IgG fraction to rabbit IgG (whole molecule) product is suitable for use as a reagent in enzyme immunoassays (EIA), cell and tissue staining (for light microscopy), cell and tissue labeling (for electron microscopy), and blot immunostaining. (mpbio.com)
  • We postulated that one or more peroxidases produced by Caenorhabditis elegans would act in host defense, possibly in conjunction with BLI-3 , the only NOX/DUOX enzyme encoded by the genome that is expressed. (genetics.org)
  • This study investigated the effect of curcumin on aluminium-induced alterations in ageing-related parameters: lipid peroxidation, superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione-s-transferase (GST), protein kinase C (PKC), Na(+), K(+)-adenosine triphosphatase (Na(+), K(+)-ATPase) and acetylcholinesterase (AChE) in the cerebral cortex and hippocampus of the brain of 10- and 24-month-old rats. (nih.gov)
  • The aim of the present study is to evaluate the effect of Zn excess on the non-enzymatic (anthocyanin and ß-ecdysone) and enzymatic (superoxide dismutase-SOD and guaiacol peroxidase-GPX) antioxidant system of two P. glomerata accessions (JB and GD) grown in hydroponic system and soil, under short- and long-term exposure times. (bvsalud.org)
  • The present light and transmission electron microscopic study reveals that the cationic surfactant, benzalkonium chloride, which is commonly added to eye drops as a preservative, breaks down this barrier. (scite.ai)
  • Symptoms are exacerbated by the preservative benzalkonium chloride (BKC) in the nasal preparations. (springer.com)
  • Another commonly used FQ, levofloxacin (LEV), and the most commonly used preservatives, benzalkonium chloride (BAC), were also used for comparison with MOX. (arvojournals.org)
  • We investigated the therapeutic effects and underlying mechanisms of topical doxycycline in a benzalkonium chloride (BAC)-induced mouse dry eye model. (arvojournals.org)
  • For example, although eosinophil peroxidase is able to oxidize chloride, it preferentially oxidizes bromide. (wikipedia.org)
  • The eosinophil number in blood and eosinophil protein levels in serum (serum eosinophil cationic protein [ECP] and serum eosinophil peroxidase [EPO]) increased significantly in the withdrawal group, and the difference between the groups was significant (P =.02 for all). (nih.gov)
  • Chloride-transporting proteins (CLC) play fundamental roles in many tissues in the plasma membrane as well as in intracellular membranes. (hmdb.ca)
  • In other words, the proteins are trapped between glycine and chloride ion. (ipl.org)
  • Peroxidases form a complex family of proteins that catalyze the oxidoreduction of various substrates using H 2 O 2 . (plantphysiol.org)
  • Many of these peroxidases are functionally associated with members of the NADPH oxidase (NOX)/dual oxidase (DUOX) family of proteins. (genetics.org)
  • therefore, the present study aimed to examine the ameliorative effects of grape seed extract (GSE) on cadmium chloride (CdCl2)‑induced testicular dysfunction of Wistar rats. (spandidos-publications.com)
  • Within 24 h of intramuscular administration of cadmium chloride 15 mg.kg-1 body weight (bw) and mercury chloride 20 mg.kg-1 bw, thyroid peroxidase activity increased significantly over the control with a concomitant rise in the triiodothyronine (T3) titre. (ithyroid.com)
  • The present study evaluated the protective effects of Fragaria ananassa methanolic extract (SME) on cadmium chloride (CdCl 2 )-induced neuronal toxicity in rats. (bioscirep.org)
  • Haloperoxidases are peroxidases that are able to mediate the oxidation of halides by hydrogen peroxide. (wikipedia.org)
  • The Nernst equation shows that hydrogen peroxide can oxidize chloride (E°= 1.36 V), bromide (E°= 1.09 V) and iodide (E°= 0.536 V) from a thermodynamic perspective under natural conditions, i.e., a temperature range of about 0-30 °C and a pH ranging from about 3 (humic soil layer) to about 8 (sea water). (wikipedia.org)
  • For example, myeloperoxidase (MPO) of neutrophils employs chloride as a substrate and forms hypochlorous acid as the main product ( Klebanoff, 2005 ). (frontiersin.org)
  • Lactoperoxidase (LPO) of milk and salivary peroxidase (SPO) of saliva readily oxidize thiocyanate (SCN − ) and generate hypothiocyanous acid or its conjugate base hypothiocyanite (OSCN − ), the latest being predominant in most physiological fluids ( Chandler and Day, 2012 ). (frontiersin.org)
  • 7. The enzymatic material of claim 5 wherein the peroxidatic peroxidase is lactoperoxidase. (google.com)
  • Glutathione Peroxidase antibody LS-C194677 is an unconjugated mouse monoclonal antibody to human Glutathione Peroxidase (GPX1). (lsbio.com)
  • By using tissue-specific skpo-1 RNAi and immunohistochemical localization with an anti- SKPO-1 antibody, it was determined that the peroxidase is functionally and physically present in the hypodermis. (genetics.org)
  • HEME-containing peroxidases play critical, wide-ranging roles in biological systems. (genetics.org)
  • It also decreases glutathione peroxidase in the kidneys while regulating heme oxidase function. (naturalnews.com)
  • Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. (drugbank.ca)
  • However, a peroxidase exerts an antimicrobial effect indirectly by catalyzing the transformation of a substrate with low antimicrobial properties into one with high antimicrobial effects ( Klebanoff, 1967 ). (frontiersin.org)
  • In contrast to trospium chloride, brain penetration of oxybutynin is not restricted by the drug efflux carrier P-glycoprotein because oxybutynin is not a P-glycoprotein substrate in vivo . (urotoday.com)
  • Peroxidase-catalyzed oxidation of (pseudo)halides yields reactive agents which oxidize microorganisms, damaging essential structural and functional components and causing inhibition of microbial metabolism and growth ( Thomas and Fishman, 1986 ). (frontiersin.org)
  • The peroxidase-catalyzed oxidation of I − yields molecular iodine (I 2 ) and, depending on I − concentration and pH, hypoiodous acid and hypoiodite (OI − ), or else, other iodine species may be present ( Kussendrager and van Hooijdonk, 2000 ). (frontiersin.org)
  • 13. The enzymatic material of claim 5 which also contains, per gram of material, from about 0.0001to about 0.01 millimole of a metal salt of an oxygen accepting anion selected from the group consisting of thiocyanate, chloride and iodine or mixtures of such salts. (google.com)
  • This study was conducted to investigate the effect of Zinc Chloride on streptozotocin-induced diabetic nephropathy in rats compared to Gliclazide, a reference antidiabetic agent. (scirp.org)
  • Effects of Berberine chloride on the liver of streptozotocin-induced diabetes in albino Wistar rats. (greenmedinfo.com)
  • Different peroxidases preferably oxidize different (pseudo)halides, generating distinct antimicrobial species. (frontiersin.org)
  • Finally, Zinc Chloride was able to boost the antioxidant defenses of the kidney by increasing the reduced glutathione content and decreasing lipid peroxides content in addition to significantly decreasing kidney nitric oxide content compared to diabetic control rats. (scirp.org)
  • The administration of berberine chloride notably recovered the liver from hyperglycemia induced antioxidant imbalance, inflammation and apoptosis. (greenmedinfo.com)
  • The SKPO-1 protein contains the critical catalytic residues necessary for peroxidase activity, and in a whole animal assay, more H 2 O 2 was detected from the mutant compared to the wild type, consistent with the loss of an H 2 O 2 sink. (genetics.org)
  • Chloride ions have important physiological roles. (hmdb.ca)
  • The following study showed that the administration of mercury in the form of mercuric chloride causes significant alterations in copper and zinc metabolism, but does not seem to affect iron metabolism. (ithyroid.com)
  • Effect of astaxanthin on kidney function impairment and oxidative stress induced by mercuric chloride in rats. (unboundmedicine.com)
  • Mercuric chloride (HgCl2), additionally, is known to debilitate the function of other organelles such as lysosomes that hold transmembrane proton gradient. (naturalnews.com)
  • The amount of chloride in the blood is carefully controlled by the kidneys. (hmdb.ca)
  • 5. The enzymatic material of claim 1 which also contains from about 0.1 to about 10,000 International Units of peroxidatic peroxidase per gram of material. (google.com)
  • CAT also acts as a peroxidase, but its 'peroxidatic' activity also called 'peroxidatic' reaction is relatively slow and noticeable at low H 2 O 2 concentration. (media.pl)
  • This study was performed to compare tissue distribution and brain penetration of the anticholinergic drugs trospium chloride and oxybutynin in a mouse model. (urotoday.com)
  • The purposes of the present study were to: (1) compare tissue distribution of trospium chloride versus oxybutynin, and (2) analyze brain penetration and drug excretion of oxybutynin in P-gp deficient knockout mice. (urotoday.com)
  • Peroxidase-conjugated goat IgG fraction to human IgG Fc is used in immunostaining of acetone-fixed frozen and formalin-fixed, paraffin-embedded tissue sections. (mpbio.com)
  • As a model, we used human SH-SY5Y neuroblastoma cells after treatment with the hypoxia-mimetic cobalt chloride and analyzed differences in the gene expression profiles in comparison to untreated cells. (thisisms.com)
  • Five genes were found to be strongly up-regulated in SH-SY5Y cells after treatment with cobalt chloride: clusterin, glutathione peroxidase 3, insulin-like growth factor 2, solute carrier family 7 member 11, and neural precursor cell expressed developmentally down-regulated protein 9. (thisisms.com)
  • The chloride ion is an essential anion that the body needs for many critical functions. (hmdb.ca)
  • In addition to the data part, the report also provides overview of 4-ethoxybenzoyl chloride market, including classification, application, manufacturing technology, industry chain analysis and latest market dynamics. (absolutereports.com)
  • Displays glutathione peroxidase activity with cumene hydroperoxide. (drugbank.ca)