Chlorhexidine
Anti-Infective Agents, Local
Mouthwashes
Disinfectants
Povidone-Iodine
Root Canal Irrigants
Sodium Hypochlorite
Soaps
Dental Disinfectants
Baths
Calcium Hydroxide
Cetrimonium Compounds
Dental Plaque
Disinfection
Cetylpyridinium
Cariostatic Agents
Benzalkonium Compounds
Dental Pulp Cavity
2-Propanol
Dentin
Root Canal Preparation
Hand Disinfection
Hexachlorophene
Porphyromonas endodontalis
Calcium Fluoride
Colony Count, Microbial
Sterilization
Materials Testing
Biofilms
Streptococcus mutans
Dry Socket
Mupirocin
Thymol
Smear Layer
1-Propanol
Vascular Access Devices
Dental Materials
Streptococcus sobrinus
Administration, Topical
Equipment Contamination
Umbilical Cord
Toothbrushing
Dental Caries
Dental Leakage
Triclosan
Iodophors
Enterococcus faecalis
Polyhydroxyethyl Methacrylate
Root Canal Filling Materials
Skin Care
Tooth Demineralization
Oral Hygiene
Salivary contribution to exhaled nitric oxide. (1/615)
Dietary and metabolic nitrate is distributed from the blood to the saliva by active uptake in the salivary glands, and is reduced to nitrite in the oral cavity by the action of certain bacteria. Since it has been reported that nitric oxide may be formed nonenzymatically from nitrite this study aimed to determine whether salivary nitrite could influence measurements of exhaled NO. Ten healthy subjects fasted overnight and ingested 400 mg potassium nitrate, equivalent to approximately 200 g spinach. Exhaled NO and nasal NO were regularly measured with a chemiluminescence technique up to 3 h after the ingestion. Measurements of exhaled NO were performed with a single-breath procedure, standardized to a 20-s exhalation, at a flow of 0.15 L x s(-1), and oral pressure of 8-10 cmH2O. Values of NO were registered as NO release rate (pmol x s(-1)) during the plateau of exhalation. Exhaled NO increased steadily over time after nitrate load and a maximum was seen at 120 min (77.0+/-15.2 versus 31.2+/-3.0 pmol x s(-1), p<0.01), whereas no increase was detected in nasal NO levels. Salivary nitrite concentrations increased in parallel; at 120 min there was a four-fold increase compared with baseline (1.56+/-0.44 versus 0.37+/-0.09 mM, p<0.05). The nitrite-reducing conditions in the oral cavity were also manipulated by the use of different mouthwash procedures. The antibacterial agent chlorhexidine acetate (0.2%) decreased NO release by almost 50% (p<0.01) 90 min after nitrate loading and reduced the preload control levels by close to 30% (p<0.05). Sodium bicarbonate (10%) also reduced exhaled NO levels, but to a somewhat lesser extent than chlorhexidine acetate. In conclusion, salivary nitric oxide formation contributes to nitric oxide in exhaled air and a large intake of nitrate-rich foods before the investigation might be misinterpreted as an elevated inflammatory activity in the airways. This potential source of error and the means for avoiding it should be considered in the development of a future standardized method for measurements of exhaled nitric oxide. (+info)Disinfection of upper gastrointestinal fibreoptic endoscopy equipment: an evaluation of a cetrimide chlorhexidine solution and glutaraldehyde. (2/615)
There is little information available on the bacteriological contamination of upper gastrointestinal fibreoptic endoscopes during routine use and the effects of 'disinfecting solutions'. A bacteriological evaluation was therefore made of cleaning an endoscope and its ancillary equipment with (1) water, (2) an aqueous solution of 1% cetrimide with 0.1% chlorhexidine, and (3) activated aqueous 2% glutaraldehyde. All equipment, but particularly the endoscope itself, was found to be heavily contaminated after use with a wide variety of organisms of which 53% were Gram positive. Cleaning the endoscope and ancillary equipment with water and the cetrimide/chlorhexidine solution alone or in combination was inadequate to produce disinfection but immersion in glutaraldehyde for two minutes consistently produced sterile cultures with our sampling technique. A rapid and simple method for disinfection of endoscopic equipment is therefore recommended and we think this is especially suitable for busy endoscopy units. (+info)Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine. (3/615)
Matrix metalloproteinases (MMPs) are a host cell-derived proteolytic enzyme family which plays a major role in tissue-destructive inflammatory diseases such as periodontitis. The aim of the present study was to evaluate the inhibitory effect of chlorhexidine (CHX) on MMP-2 (gelatinase A), MMP-9 (gelatinase B), and MMP-8 (collagenase 2) activity. Heat-denatured type I collagen (gelatin) was incubated with pure human MMP-2 or -9 activated with p-aminophenylmercuric acetate (APMA), and the proteolytic degradation of gelatin was monitored by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Coomassie blue staining. The effect of CHX on MMP-8 activity was also studied with a cellular model addressing the ability of phorbol myristate acetate (PMA)-triggered human peripheral blood neutrophils (polymorphonuclear leukocytes [PMNs]) to degrade native type I collagen. CHX inhibited the activities of both gelatinases (A and B), but MMP-2 appeared to be more sensitive than MMP-9. Adding calcium chloride to the assay mixtures almost completely prevented the inhibition of MMP-9 activity by CHX, while the inhibition of MMP-2 activity could be reversed only when CHX was used at a low concentration. This observation suggests that CHX may act via a cation-chelating mechanism. CHX dose-dependently inhibited collagenolytic activity of MMP-8 released by PMA-triggered PMNs. MMP-8 without APMA activation was inhibited clearly more efficiently than APMA-activated MMP-8. Our study suggests that the direct inhibition of the MMPs' activities by CHX may represent a new valuable effect of this antimicrobial agent and explains, at least in part, the beneficial effects of CHX in the treatment of periodontitis. (+info)Antimicrobial susceptibility and composition of microcosm dental plaques supplemented with sucrose. (4/615)
The aims of this study were to evaluate the effects of repeated chlorhexidine gluconate (CHG) pulsing on the viability and bacterial composition of microcosm dental plaques derived from human saliva. The biofilms were grown on bovine enamel discs in a constant-depth film fermentor fed with an artificial saliva which was supplemented thrice daily with sucrose. The microcosm plaques had total viable anaerobic counts of 5 x 10(8) CFU per mm2 and consisted of 12% Actinomyces spp., 85% streptococci, and 0.2% Veillonella spp. When pulsed twice daily with 0.2% CHG, there was an immediate 1.3-log10 reduction in the total viable (anaerobic) count. However, as pulsing continued, the viable counts recovered, and after 4 days, the anaerobic count reached its pre-CHG-pulsing level, although the bacterial composition of the biofilms had changed. The results of this study show that twice-daily pulsing with 0.2% CHG over a 4-day period was ineffective at reducing the total anaerobic viable count of the biofilms but did alter their bacterial composition. (+info)Can group B streptococci cause symptomatic vaginitis? (5/615)
BACKGROUND: Maternal cervicovaginal colonization with Lancefield group B streptococci (GBS) is an important risk factor for neonatal morbidity and mortality. About 15% of women are carriers of GBS. Usually, they are asymptomatic. CASES: We describe two patients with symptomatic vaginitis for which no apparent cause was found. Both patients were heavily colonized with GBS. After antibiotic treatment, both became asymptomatic and culture negative, but after recolonization with GBS, symptoms resumed. This phenomenon was repeatedly observed. After emergence of resistance to antibiotics, local application of chlorhexidine appeared to be the only useful treatment. CONCLUSION: We hypothesize that GBS-vaginitis may be a possible disease entity. Although at present it is not clear why some patients become symptomatic, we speculate that the immunologic response is somehow selectively hampered in such patients. (+info)A clinical comparison of the efficacy and efficiency of two professional prophylaxis procedures in orthodontic patients. (6/615)
This study compared the efficacy and efficiency of two professional prophylaxis procedures in orthodontic patients performing different oral hygiene regimens: the air powder polishing system (APP), and the rubber cup and pumice (RCP) technique. Sixty-two patients were divided into two groups: group I included 40 subjects who did not use any chlorhexidine mouthwash and group II comprised 22 subjects who regularly rinsed with a chlorhexidine mouthwash (at a 0.12 per cent concentration) and showed increased tooth staining. Using a split-mouth experimental design, the buccal and lingual tooth surfaces were cleaned in half of the mouth by the APP and in the opposite half by the RCP technique. Tooth surfaces were scored before (PRE) and after (POST) the experimental procedures for the plaque index (PI), and for the presence of tooth staining. In addition, the treatment time required by each procedure was recorded. In test group I, significant reductions in the PI after APP and RCP were observed. Likewise, in test group II, both procedures significantly reduced the baseline PI values. In both experimental groups, the percentage of stained sites significantly decreased after APP and RCP, but in test group II, APP seemed to be more effective than RCP. In addition, APP required significantly less time than RCP to remove dental plaque and staining. These data show that both professional prophylaxis procedures are effective in orthodontic patients, with APP being the most time-efficient technique and the most effective method for removal of tooth staining. (+info)N-acetylneuraminic acid transport by Streptococcus oralis strain AR3. (7/615)
Streptococcus oralis has emerged as one of the most important organisms of the viridans streptococcus group in terms of infections and is recognised as an agent of infective endocarditis and, in immunocompromised patients, septicaemia. The mechanisms by which this organism proliferates in vivo are unknown. However, host-derived sialic acids -- including N-acetylneuraminic acid (NeuNAc) which is present in serum and cell-associated glycoproteins -- are a potential source of fermentable carbohydrate for bacterial proliferation, especially for sialidase-producing bacteria, including S. oralis. To further elucidate the role of NeuNAc in supporting growth, this study determined the ability of S. oralis strain AR3 (isolated from a patient with infective endocarditis) to transport NeuNAc and characterised the transport system. The transport of [14C]-labelled NeuNAc into S. oralis was monitored and this transport system was induced by growth of the bacteria in the presence of the N-acetylated sugars NeuNAc, N-acetylglucosamine and N-acetylmannosamine. The transport system followed typical Michaelis-Menten kinetics, with a Km of 21.0 microM and a Vmax of 2.65 nmoles of NeuNAc transported/min/mg of dry cell mass. NeuNAc transport was inhibited by the presence of exogenous N-glycolylneuraminic acid, a related sialic acid. Chlorhexidine, NaF and 2,4-dinitrophenol were potent inhibitors of the transport system, suggesting that the uptake of NeuNAc occurs via a proton motive force-dependent permease system. This is the first report of the mechanism by which NeuNAc transport occurs in pathogenic streptococci. This transport process may have relevance to the acquisition of a source of fermentable carbohydrate and thus bacterial proliferation in vivo. (+info)Chlorhexidine and chondrolysis in the knee. (8/615)
We have summarised the clinical and pathological changes in the knees of three patients in whom aqueous chlorhexidine 0.02% had been used as the irrigation solution during arthroscopically-assisted reconstruction of the anterior cruciate ligament. Even very dilute solutions of chlorhexidine can cause marked chondrolysis of articular cartilage leading to severe permanent damage to the knee. Irrigation solutions should be checked carefully to ensure that their composition is appropriate to the procedure being carried out. Exposure of articular cartilage to chlorhexidine should be avoided. (+info)Plaque is a key risk factor for dental caries (tooth decay) and periodontal disease, which can lead to tooth loss if left untreated. In addition, research suggests that there may be a link between oral bacteria and certain systemic diseases, such as heart disease and diabetes. Therefore, maintaining good oral hygiene practices, such as regular brushing and flossing, is essential to prevent the accumulation of plaque and promote overall health.
Gingivitis can be treated with good oral hygiene practices, such as brushing and flossing regularly, and by visiting a dentist for regular check-ups and professional cleanings. If left untreated, gingivitis can progress to periodontitis, a more severe form of gum disease that can lead to permanent damage and tooth loss.
Some common symptoms of gingivitis include:
* Red and swollen gums
* Bleeding during brushing or flossing
* Bad breath
* Tenderness or pain in the gums
* A decrease in the amount of saliva
Treatment for gingivitis typically involves a combination of good oral hygiene practices and professional dental care. This may include:
* Regular brushing and flossing to remove plaque and bacteria from the teeth
* Professional cleanings ( scaling and root planing) to remove plaque and tartar from the teeth
* Antibiotics to treat any underlying infections
* Changes to diet and lifestyle to reduce the risk of further irritation to the gums.
It's important to note that while gingivitis is a mild form of gum disease, it can still have serious consequences if left untreated. Regular dental check-ups and good oral hygiene practices are essential for preventing and treating gingivitis.
The symptoms of dry socket usually become apparent within 3-4 days after the extraction, and may include:
* Pain or discomfort in the affected area, which can radiate to the surrounding tissues
* Swelling and redness of the gums around the extraction site
* Foul odor or taste from the exposed bone and nerve endings
* Difficulty opening the mouth or swallowing
* Increased sensitivity to hot or cold temperatures
If you suspect that you have developed a dry socket, it is important to contact your dentist or oral surgeon as soon as possible. Treatment for dry socket typically involves placing a medicated dressing over the affected area to promote healing and manage pain. In severe cases, your dentist may need to perform additional surgery to restore the socket and promote healing.
Preventing dry sockets is important, and there are several steps you can take to reduce your risk of developing this condition after a tooth extraction. These include:
* Avoiding vigorous mouth rinsing or spitting for at least 24 hours after the extraction
* Avoiding smoking or using straws for at least 24 hours after the extraction
* Eating soft, nutritious foods and avoiding hot, hard, or crunchy foods for a few days after the extraction
* Taking pain medication as directed by your dentist or oral surgeon to manage discomfort
* Following your dentist's instructions carefully to promote healing and prevent complications.
The presence of a smear layer has been associated with delayed healing, increased risk of infection, and decreased strength of the newly formed tissue. Therefore, removing or reducing the smear layer is an important step in wound care to promote optimal healing outcomes.
The term "smear layer" was first introduced by Dr. Jeffrey M. Olsen and colleagues in 2007, and since then it has been widely adopted in the medical field as a key concept in wound care.
Prevention includes regular dental check-ups, good oral hygiene practices such as brushing and flossing, a balanced diet, avoiding sugary snacks and drinks, and quitting smoking. Treatment options may include fillings, crowns, root canals, and extractions.
Root caries is different from other types of tooth decay, such as coronal caries, which affects the crown or enamel of the tooth. It requires specialized dental care and attention to prevent and treat effectively.
Symptoms may include sensitivity, discomfort, visible holes or stains on teeth, bad breath, and difficulty chewing or biting. If left untreated, dental caries can progress and lead to more serious complications such as abscesses, infections, and even tooth loss.
To prevent dental caries, it is essential to maintain good oral hygiene habits, including brushing your teeth at least twice a day with fluoride toothpaste, flossing daily, and using mouthwash regularly. Limiting sugary foods and drinks and visiting a dentist for regular check-ups can also help prevent the disease.
Dental caries is treatable through various methods such as fillings, crowns, root canals, extractions, and preventive measures like fissure sealants and fluoride applications. Early detection and prompt treatment are crucial to prevent further damage and restore oral health.
1. Improper fit of dental restorations (fillings, crowns, etc.)
2. Inadequate sealing of dental implants
3. Loose or damaged dental restorations
4. Poor oral hygiene
5. Trauma to the mouth
6. Inadequate suction during dental procedures
Dental leakage can have significant consequences, including:
1. Bacterial contamination of the surgical site
2. Delayed healing
3. Increased risk of post-operative complications
4. Decreased success rate of dental procedures
5. Potential for infection or other adverse events
To minimize the risk of dental leakage, dentists should:
1. Use proper technique and instrumentation during dental procedures
2. Ensure proper fit and sealing of dental restorations
3. Maintain proper oral hygiene before and after dental procedures
4. Use adequate suction during dental procedures
5. Monitor the surgical site for signs of leakage or other complications.
Early detection and treatment of dental leakage can help prevent serious complications and ensure a successful outcome for dental procedures.
Demineralization is the opposite process of remineralization, where minerals are deposited back onto the tooth surface. Demineralization can progress over time and lead to tooth decay, also known as dental caries, if not treated promptly. Early detection and prevention of demineralization through good oral hygiene practices and regular dental check-ups can help to prevent tooth decay and maintain a healthy tooth structure.
Tooth demineralization can be detected early on by dental professionals using various diagnostic tools such as radiographs (x-rays) or visual examination of the teeth. Treatment options for demineralization depend on the severity of the condition and may include fluoride treatments, fillings, or other restorative procedures to repair damaged tooth structures.
It is important to maintain good oral hygiene practices such as brushing twice a day with fluoride toothpaste, flossing once a day, and limiting sugary snacks and drinks to prevent demineralization and promote remineralization of the teeth. Regular dental check-ups are also crucial in detecting early signs of demineralization and ensuring proper treatment to maintain good oral health.
There are several types of tooth discoloration, including:
1. Extrinsic stains: These are the most common type of tooth discoloration and are caused by factors such as coffee, tea, red wine, and smoking. These stains can be removed with professional cleaning and whitening treatments.
2. Intrinsic stains: These are deeper stains that occur within the tooth itself and can be caused by factors such as fluorosis, tetracycline staining, and overexposure to fluoride during childhood. These stains can be more difficult to remove and may require more advanced treatments such as porcelain veneers or teeth whitening.
3. Age-related discoloration: As we age, our teeth can become naturally more yellow due to the accumulation of calcium and other minerals on the surface of the teeth. This type of discoloration is more common in adults over the age of 40.
4. Trauma: A blow to the mouth or a injury to a tooth can cause discoloration.
5. Disease: Certain medical conditions such as bruxism, gum disease, and enamel defects can also cause tooth discoloration.
Tooth discoloration can be treated with various methods such as teeth whitening, dental bonding, porcelain veneers, and crowns. The choice of treatment depends on the severity and cause of the discoloration. It is important to consult a dentist if you notice any changes in the color of your teeth, as early diagnosis and treatment can help prevent further damage and improve the appearance of your smile.
Chlorhexidine
Index of oral health and dental articles
WHO Surgical Safety Checklist
Picloxydine
Chronic periodontitis
Periodontology
Mouthwash
Childbirth
Cystoscopy
Polyacrylic acid
Streptococcus sobrinus
Peter Pronovost
Save the Children State of the World's Mothers report
Alexidine
Virucide
Bad breath
Tonsil stones
Hysterosalpingography
Dental health diets for dogs
Toothpaste
Local anesthetic
Delftia acidovorans
Thymol
Denture-related stomatitis
Decolonization (medicine)
Scaling and root planing
Cutibacterium acnes
Miswak
Pulpotomy
Eclabium
DailyMed - Search Results for Chlorhexidine
DailyMed - CHLORHEXIDINE GLUCONATE solution
Updated Recommendations on Chlorhexidine-Impregnated (C-I) Dressings | Infection Control | CDC
MedlinePlus - Search Results for: CHLORHEXIDINE
Obstetric Care (Chlorhexidine Gluconate) Orion Pharma
Consepsisâ„¢ V-2% Chlorhexidine Antibacterial Viscous Solution
Chlorhexidine allergy - Australasian Society of Clinical Immunology and Allergy (ASCIA)
Effects of Buprenorphine, Chlorhexidine, and Low-level Laser Therapy on Wound Healing in Mice
Risk management approach for chlorhexidine and its salts - Canada.ca
Madagascar Chlorhexidine Poster - Healthy Newborn Network
Chlorhexidine - Drugs and Lactation Database (LactMed®) - NCBI Bookshelf
Chlorhexidine glutonate solution reduces hospital-acquired bloodstream infections - Water Quality and Health Council
Burkholderia lata Infections from Intrinsically Contaminated Chlorhexidine Mouthwash, Australia, 2016 - Volume 24, Number 11...
Betasept, Hibiclens (chlorhexidine topical) dosing, indications, interactions, adverse effects, and more.
Effects of Buprenorphine, Chlorhexidine, and Low-level Laser Therapy on Wound Healing in Mice - PubMed
Clinical and radiographic evaluation for local drug delivery of chlorhexidine chip in chronic periodontitis | International...
chlorhexidine dog shampoo
Human dentin bond strength of a chlorhexidine containing universal adhesive system used in total-etch and self-etch mode
Chlorhexidine Nigeria | Footprints Foundation
Mouthwash chlorhexidine 16.9 fl.oz
Controlling Streptococcus mutans and Staphylococcus aureus biofilms with direct current and chlorhexidine<...
Does chlorhexidine prevent wound healing? - Snappy1
Chlorhexidine Gluconate Wipes Market Archives - Newshunt360
Chlorhexidine Gluconate Details and Information - BuzzRx
CHLORHEXIDINE 0.05% & CETRIMIDE 0 | KARI Aboriginal Procurement
Antibacterial mouthwash with Chlorhexidine | CURAPROX-Shop Schweiz
Chlorhexidine: A Study in Microbial and Macrobial Superheroes
CHLORHEXIDINE GAUZEDRESSING BP 93 - Dr Sabharwal's Wound Care
Chlorhexidine in Endodontics | Braz. dent. j;24(2): 89-102, Mar-Apr/2013. | LILACS
Gluconate11
- Chlorhexidine gluconate skin cleansers will cause stains if used with chlorine releasing products, such as chlorine bleach. (nih.gov)
- gel (Lidex), anti-inflammatory amlexanox paste (Aphthasol), or chlorhexidine gluconate (Peridex) mouthwash. (nih.gov)
- designed to help combat moderate conditions associated with bacteria and a wide range of microorganisms, this shampoo is formulated with 2% chlorhexidine gluconate for soothing relief. (outlinelab.com)
- chlorhexidine gluconate 4% in dog shampoos means that the shampoo will provide antiseptic action and a persistent antimicrobial effect against a range of microorganisms. (outlinelab.com)
- davis chlorhexidine pet shampoo with 2% chlorhexidine gluconate is formulated for skin conditions caused by microorganisms and bacteria. (outlinelab.com)
- Purpose: Despite the lack of safety data, chlorhexidine gluconate (CHG) is an antiseptic with broadspectrum coverage often used in neonatal intensive care units (NICUs). (snappy1.org)
- Does chlorhexidine gluconate burn your tongue? (snappy1.org)
- Is chlorhexidine gluconate safe for skin? (snappy1.org)
- Can you wash your face with chlorhexidine gluconate? (snappy1.org)
- A Recent Report by Research Nester titled "Global Chlorhexidine Gluconate Wipes Market: Demand Analysis & Opportunity Outlook 2027" delivers detailed overview of the global chlorhexidine gluconate wipes market. (newshunt360.com)
- It can be used as a powder or in a liquid solution and is commonly found in chlorhexidine gluconate or digluconate form. (getcompel.com)
Mouthwash11
- Whole-genome sequencing demonstrated that clinical and environmental isolates originated from a batch of contaminated commercial chlorhexidine mouthwash. (cdc.gov)
- During May-June 2016, bacterial contamination of chlorhexidine mouthwash (0.2% mg/mL) was associated with an interjurisdictional outbreak in New South Wales and South Australia. (cdc.gov)
- An investigation by the hospital's infection and prevention control team noted discoloration of a commercial chlorhexidine mouthwash. (cdc.gov)
- Phylogenetic analysis of isolates implicated in an outbreak Burkholderia lata infection from intrinsically contaminated chlorhexidine mouthwash, Australia, 2016. (cdc.gov)
- Can I use chlorhexidine mouthwash every day? (snappy1.org)
- When should I stop using chlorhexidine mouthwash? (snappy1.org)
- A mouthwash with Chlorhexidine that doesn't taste bitter? (curaprox.ch)
- dental caries oral health streptococcus mutans black tea extract mouth-rinse chlorhexidine mouthwash. (who.int)
- Khade R, Saawarn S, Mishra SD, Einstein A, Rathore A, Shankar T.. Comparative Evaluation of the Effects of Black Tea Extract Mouthrinse and Chlorhexidine Mouthwash on Salivary Streptococcus Mutans Load. (who.int)
- The differences in the Colony Forming Units and count-scores of S.mutans were analyzed in salivary samples collected from individuals before and after administration of 2% black tea extract mouth-rinse and chlorhexidine mouthwash(CM). Results- There was a statistical difference in mean salivary S. mutans colony count and mean count- score before and after administration of black tea extract mouth-rinse (p = 0.0003) and chlorhexidine mouthwash (p = 0.0002) respectively. (who.int)
- Hence, it was found that there is no statistically significant difference in the fall of S.mutans load due to black tea mouth-rinse and chlorhexidine mouthwash. (who.int)
Digluconate3
- An updated draft screening assessment was published in August 2017 to more broadly address the chlorhexidine moiety by considering chlorhexidine and its salts, including, but not limited to, chlorhexidine (CAS RN 55-56-1), chlorhexidine diacetate (CAS RN 56-95-1), chlorhexidine digluconate (CAS RN 18472-51-0), and chlorhexidine dihydrochloride (CAS RN 3697-42-5) (Canada 2017a). (canada.ca)
- Objective: to assess the dimensional accuracy of plaster casts obtained from irreversible hydrocolloid impressions containing anti-microbial agent, which was mixed with either water or 0.2% chlorhexidine digluconate aqueous solution. (bvsalud.org)
- Conclusion: according to the results of this study and considering its limitations, the dimensional differences between plaster casts obtained from irreversible hydrocolloid impressions manipulated with either water or 0.2% chlorhexidine digluconate were not statistically different. (bvsalud.org)
Acetate3
- A substance, chlorhexidine acetate (also known as chlorhexidine diacetate), Chemical Abstracts Service Registry Number (CAS RN) Footnote 3 56-95-1, was identified as a priority for assessment under the Chemicals Management Plan. (canada.ca)
- It was noted that chlorhexidine diacetate is a salt, and dissociates in water to produce the acetate counterion and chlorhexidine. (canada.ca)
- Chlorhexidine Acetate with Cetrimide Antiseptic Solution is used as a general antiseptic. (kariaboriginalprocurement.org.au)
Rinse2
Povidone-iodine5
- Iodine milk levels were measured in a study of mothers who received 10% povidone-iodine (n = 21) or chlorhexidine (n = 13) topically to the perineum starting immediately before the final stage of labor and daily postpartum to the episiotomy. (nih.gov)
- At 96 hours postpartum, milk iodine levels averaged 1.2 mg/L in mothers who received topical povidone-iodine compared to average milk levels of 0.1 mg/L in the mothers who received chlorhexidine. (nih.gov)
- At 96 hours postpartum, the breastfed infants (n = 13) whose mothers received povidone-iodine had urine iodine levels of 8.3 mg/L compared to levels of 0.4 mg/L in infants who did not breastfeed (n = 8) and 0.6 mg/L in the infants of mothers who received chlorhexidine (n = 13). (nih.gov)
- 2 ] After replacing povidone-iodine with chlorhexidine 0.5% in 70% isopropanol for disinfection for 6 months, 1178 infants that were delivered at this institution had no increased rate of elevations in thyroid function tests and a reduced rate of recalls in breastfed infants. (nih.gov)
- In a study of mothers in Spain who received 10% povidone-iodine (n = 21) or chlorhexidine (n = 13) topically to the perineum starting immediately before the final stage of labor and daily postpartum to the episiotomy, no differences in thyrotropin, thyroxine or free thyroxine was found among their breastfed infants at day 5 to 7 postpartum. (nih.gov)
Antimicrobial4
- An antibacterial agent, chlorhexidine is ideal for endodontic use due to its ability to bind to hydroxyapatite, creating a long-lasting antimicrobial effect. (ultradent.com)
- CHLORHEXIDINE is a powerful antimicrobial component. (globalwhite.com)
- Chlorhexidine and alcohol combine to produce a "synergistic residual antimicrobial effect," 1 which is fun to say when talking to medical professionals. (getcompel.com)
- The irony here is that while carbomers rob chlorhexidine of its persistent antimicrobial activity, the gel hand sanitizer still stops killing germs when it dries. (getcompel.com)
20171
- Wang, H & Ren, D 2017, ' Controlling Streptococcus mutans and Staphylococcus aureus biofilms with direct current and chlorhexidine ', AMB Express , vol. 7, no. 1, 204. (syr.edu)
Bacteria4
- Chlorhexidine is an antiseptic which kills most bacteria. (snappy1.org)
- In addition to the power of Chlorhexidine and Citrox®, Perio Plus + mouthwashes also contain the copolymer PVP-VA. This creates a strong, protective film on the teeth and gums… and combats bacteria without drying out the mouth. (curaprox.ch)
- What makes chlorhexidine so special is that it is effective against bacteria (and bacterial spores), fungi, and enveloped viruses (herpes simplex virus, HIV, influenza, and RSV for example). (getcompel.com)
- Chlorhexidine kills or reduces the growth of different types of bacteria. (re-med.no)
Sodium hypochlorite2
- Chlorhexidine does not replace sodium hypochlorite as an irrigant because it does not break down organic tissue as well as NAOCl. (ultradent.com)
- Different CAS have been proposed and used, among which sodium hypochlorite (NaOCl), chlorhexidine (CHX), 17% EDTA , citric acid , MTAD and 37% phosphoric acid solution . (bvsalud.org)
Antibacterial agent1
- Chlorhexidine glutonate is the same antibacterial agent used by surgeons while scrubbing before an operation. (waterandhealth.org)
Biofilm1
- In this study, we report that the biofilm cells of S. mutans and S. aureus can be effectively killed by low-level direct current (DC) and through synergy in concurrent treatment with DC and chlorhexidine (CHX) at low concentrations. (syr.edu)
Diacetate3
- In July 2013, Health Canada and Environment and Climate Change Canada (ECCC) published a draft Screening Assessment Report (SAR) and Risk Management (RM) Scope for chlorhexidine diacetate (Canada 2013a, 2013b). (canada.ca)
- At the time, chlorhexidine diacetate was proposed to be toxic under section 64 of CEPA due to potential concerns to the environment. (canada.ca)
- Subsequent to the publications for chlorhexidine diacetate, significant new information became available regarding other potential sources of exposure to the chlorhexidine moiety. (canada.ca)
Topical3
- Topical application of chlorhexidine to the breast before and after nursing did not appear to adversely affect the breastfed infants in one study. (nih.gov)
- chlorhexidine topical decreases effects of allogeneic cultured keratinocytes and fibroblasts by Other (see comment). (medscape.com)
- Comment: Chlorhexidine topical antiseptic has been shown to be toxic to keratinocytes and human dermal fibroblasts. (medscape.com)
Therapeutic1
- Final considerations: the use of chlorhexidine as a therapeutic primer after acid etching prevents activating the metalloproteinase enzyme that degrades the collagen network, causing failure in adhesive restorations. (bvsalud.org)
Swab1
- In one, cotton soaked in 0.25% chlorhexidine solution was used to swab the vaginal walls every 4 hours from admission into labor until delivery in 4078 women. (nih.gov)
Infections2
- According to a new study conducted by Johns Hopkins University and five other hospitals, giving critically ill hospital patients a daily bath with a mild, four percent solution of chlorhexidine glutonate can dramatically cut down, by as much as 73 percent, the number of patients who develop potentially deadly bloodstream infections. (waterandhealth.org)
- designed to help combat moderate conditions associated chlorhexidine shampoos for dogs contain antiseptic ingredients that protect dogs from fungal or bacterial infections, reducing itchiness and inflammation. (outlinelab.com)
Moiety1
- It is this dissociated chlorhexidine moiety that has the potential to cause acute and chronic harm to aquatic organisms at low concentrations (Canada 2013a). (canada.ca)
Concentrations1
- Intensive rinsing with high concentrations of chlorhexidine may, after oral surgical operations, especially surgery in which bone is exposed, result in delay and disturbance of wound healing in humans. (snappy1.org)
Solution3
- 4 ] The other study used 120 mL of either 0.2% or 0.4% chlorhexidine solution as a vaginal lavage every 3 hours from admission to labor until delivery in 309 women. (nih.gov)
- Patients were bathed with a mild, four percent solution of chlorhexidine glutonate. (waterandhealth.org)
- experimental - plaster casts obtained from irreversible hydrocolloid impressions made with powder containing chlorhexidine, and manipulated with chlorhexidine solution instead of water (n = 10). (bvsalud.org)
Allergic8
- Allergic reactions to chlorhexidine are rare, but are increasing in frequency, possibly related to increased use of chlorhexidine containing products in recent years. (allergy.org.au)
- If you are allergic to chlorhexidine, you need to be aware that the presence of chlorhexidine is often not obvious. (allergy.org.au)
- As chlorhexidine can be 'hidden', for example, as a coating agent on medical devices such as central venous lines, allergic reactions can be difficult to diagnose. (allergy.org.au)
- Chlorhexidine allergic people often have more than one reaction, due to misdiagnosis or accidental re-exposure caused by inadequate labelling or awareness. (allergy.org.au)
- Immediate allergic reactions (also known as Type 1 or IgE mediated reactions) are the most serious adverse reactions to chlorhexidine. (allergy.org.au)
- A past history of other allergies such as eczema, asthma or allergic rhinitis (hay fever) does not appear to increase the risk of developing chlorhexidine allergy. (allergy.org.au)
- Irritant dermatitis and allergic contact dermatitis to chlorhexidine are annoying but not dangerous. (allergy.org.au)
- However, there are reports of people with allergic contact dermatitis who later develop immediate allergic reactions to chlorhexidine. (allergy.org.au)
Mild1
- People who develop anaphylaxis to chlorhexidine may report prior mild hives (urticaria) to chlorhexidine. (allergy.org.au)
Strength2
- To evaluate the microtensile bond strength to human dentin of a chlorhexidine containing universal adhesive system applied in the total-etch and self-etch modes. (scielo.edu.uy)
- The bond strength of a composite resin to human dentin was not affected by the use of a universal adhesive system containing chlorhexidine in its composition applied in the total-etch and self-etch mode. (scielo.edu.uy)
Alcohol2
- If you, as I, believe that the combination of a vehicle and an alien life force dedicated to protecting humans is inspiring, wait until I tell you about chlorhexidine combined with alcohol . (getcompel.com)
- Chlorhexidine not only takes up the battle but is even able to destroy some of the microorganisms that alcohol wasn't able to handle, often within 30 seconds. (getcompel.com)
Formulation1
- This information included quantities of chlorhexidine and its other salts in commerce, presence in products sold in Canada, and industry details related to the formulation of chlorhexidine-based products. (canada.ca)
Surgical3
- In the hospital setting, chlorhexidine is routinely used for handwashing and to clean the skin before performing a surgical procedure or inserting a needle. (allergy.org.au)
- Some surgical dressings, medical devices (such as central venous lines) and lubricants also contain chlorhexidine, to reduce the risk of infection. (allergy.org.au)
- Speaking of the dynamic duo, by the time Batman: The Animated Series hit television screens in the early to mid-90s, chlorhexidine was being used in FDA-approved catheters and surgical dressings, and I had (temporarily) outgrown cartoons. (getcompel.com)
Wounds3
- Is chlorhexidine good for open wounds? (snappy1.org)
- Although chlorhexidine is useful in disinfecting intact skin and cleaning dirty traumatized wounds, these agents should not be used on clean healing wounds. (snappy1.org)
- Chlorhexidine Fresenius Kabi is indicated for the disinfection of wounds and mucus membranes in connection with childbirth and for disinfection of the urethral orifice before catheter insertion. (re-med.no)
Adhesive1
- The articles were selected based on the following criteria: be written in English, Spanish, or Portuguese, be formatted as an original article, have abstracts available, address issues that relate MMPs to adhesive systems and/or the influence of chlorhexidine on these enzymes, and be published between 2005 and 2015. (bvsalud.org)
Medicines called1
- Chlorhexidine belongs to a group of medicines called antiseptic antibacterial agents. (snappy1.org)
Combine1
- They all combine proven Chlorhexidine with Citrox® natural bioflavonoids… to bring the uniquely strong antibacterial effect of Perio Plus + products. (curaprox.ch)
Mouthwashes1
- In the UK chlorhexidine mouthwashes are licensed for 30 days' use and are not recommended for routine use. (snappy1.org)
Preparations1
- If you are uncertain ask your pharmacist to help to ensure OTC preparations do not contain chlorhexidine as labels can be difficult to read and not placed in a prominent position. (allergy.org.au)
Agent3
- Chlorhexidine is a highly effective antiseptic agent. (allergy.org.au)
- therefore, it is imperative that you go for external treatments as well, such as bathing your dog with a shampoo that contains chlorhexidine-an anti-bacterial agent that fights skin problems and promotes healthy skin growth. (outlinelab.com)
- I was a fan of The Amazing Spiderman (insert web slinging sound effect here) in the late 70s when chlorhexidine was first used as an oral agent to combat plaque. (getcompel.com)
Adverse1
- Chlorhexidine-impregnated dressings are NOT recommended to protect the site of short-term, non-tunneled central venous catheters for premature neonates due to risk of serious adverse skin reactions. (cdc.gov)
Harmful1
- This document outlines the proposed risk management actions for chlorhexidine and its salts, which have been found to be harmful to the environment. (canada.ca)
Results2
- In people with immediate chlorhexidine allergy, contact with chlorhexidine results in activation of immune cells and release of histamine into the tissue. (allergy.org.au)
- It is caused by chlorhexidine directly irritating skin and results in rough, dry and scaly skin, sometimes with weeping sores. (allergy.org.au)
Care2
- So far, we do not know whether health care professionals who are frequently exposed to chlorhexidine are at increased risk of developing chlorhexidine allergy. (allergy.org.au)
- This poster was developed by PSI and partners in Madagascar for their branded chlorhexidine for umbilical cord care product, Aro Foitra . (healthynewbornnetwork.org)
Effective1
- Chlorhexidine glutonate is a simple, effective way to protect the health of hospital patients and ward off against hospital "superbugs" like MRSA, VRE, C. difficile, and other opportunistic pathogens. (waterandhealth.org)
Healthcare1
- Eye protection is recommended for healthcare workers due to the splash risk of chlorhexidine. (snappy1.org)
Skin6
- Anaphylaxis typically occurs when chlorhexidine comes in contact with internal (mucosal) surfaces or deeper tissues in the body, through an opening of the skin during a medical procedure. (allergy.org.au)
- What does chlorhexidine do to your skin? (snappy1.org)
- Can you use chlorhexidine on open skin? (snappy1.org)
- Does chlorhexidine burn the skin? (snappy1.org)
- How do you apply chlorhexidine to skin? (snappy1.org)
- Chlorhexidine has the unique ability (superpower) to bind to the proteins in human skin and mucous membranes but manages to avoid bodily absorption. (getcompel.com)
Clinical2
- Chlorhexidine-impregnated dressings with an FDA-cleared label that specifies a clinical indication for reducing catheter-related bloodstream infection (CRBSI) or catheter-associated blood stream infection (CABSI) are recommended to protect the insertion site of short-term, non-tunneled central venous catheters. (cdc.gov)
- Objective: to analyze the mechanism of action of chlorhexidine on the matrix metalloproteinases (MMPs) enzymes and their clinical impact. (bvsalud.org)
Products contain2
- Many over-the-counter (OTC) products contain chlorhexidine. (allergy.org.au)
- Perio plus products contain Chlorhexidine. (curaprox.ch)
Group2
- No recommendation can be made about the use of chlorhexidine-impregnated dressings to protect the site of short-term, non-tunneled central venous catheters for pediatric patients less than 18 years old and non-premature neonates due to the lack of sufficient evidence from published, high-quality studies about efficacy and safety in this age group. (cdc.gov)
- Aims: The aim of the present study was to evaluate the efficacy of a controlled release biodegradable chlorhexidine chip when used as an adjunct to scaling and root planing in the treatment of periodontitis Materials and Methods: In the present study, patients diagnosed with chronic periodontitis of age group, 25-60 were included. (journalcra.com)
Risk1
- The screening assessment concludes that there is risk of harm to the environment from chlorhexidine and its salts, as they meet criteria under paragraph 64(a) of the Canadian Environmental Protection Act, 1999 (CEPA). (canada.ca)
Active1
- based on the list of active ingredients, formula, and users' reviews and rating, douxo chlorhexidine ps chlorhexidine shampoo for dogs is the best antiseptic shampoo for dogs. (outlinelab.com)
Release1
- In particular, the Government of Canada is considering implementing a Code of practice under Section 54 of CEPA and an Environmental performance agreement (EPA) to minimize the release of chlorhexidine and its salts to the environment from the industrial use of these substances. (canada.ca)