Chlorhexidine
Anti-Infective Agents, Local
Mouthwashes
Disinfectants
Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Povidone-Iodine
Root Canal Irrigants
Chemicals used mainly to disinfect root canals after pulpectomy and before obturation. The major ones are camphorated monochlorophenol, EDTA, formocresol, hydrogen peroxide, metacresylacetate, and sodium hypochlorite. Root canal irrigants include also rinsing solutions of distilled water, sodium chloride, etc.
Sodium Hypochlorite
Soaps
Sodium or potassium salts of long chain fatty acids. These detergent substances are obtained by boiling natural oils or fats with caustic alkali. Sodium soaps are harder and are used as topical anti-infectives and vehicles in pills and liniments; potassium soaps are soft, used as vehicles for ointments and also as topical antimicrobials.
Dental Disinfectants
Baths
Calcium Hydroxide
Cetrimonium Compounds
Cetyltrimethylammonium compounds that have cationic detergent, antiseptic, and disinfectant activities. They are used in pharmaceuticals, foods, and cosmetics as preservatives; on skin, mucous membranes, etc., as antiseptics or cleansers, and also as emulsifiers. These compounds are toxic when used orally due to neuromuscular blockade.
Dental Plaque
Disinfection
Cetylpyridinium
Cariostatic Agents
Benzalkonium Compounds
Dental Pulp Cavity
2-Propanol
Dentin
Root Canal Preparation
Preparatory activities in ROOT CANAL THERAPY by partial or complete extirpation of diseased pulp, cleaning and sterilization of the empty canal, enlarging and shaping the canal to receive the sealing material. The cavity may be prepared by mechanical, sonic, chemical, or other means. (From Dorland, 28th ed, p1700)
Hand Disinfection
Hexachlorophene
A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Porphyromonas endodontalis
Calcium Fluoride
Colony Count, Microbial
Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
Sterilization
Materials Testing
Biofilms
Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.
Streptococcus mutans
Dry Socket
A condition sometimes occurring after tooth extraction, particularly after traumatic extraction, resulting in a dry appearance of the exposed bone in the socket, due to disintegration or loss of the blood clot. It is basically a focal osteomyelitis without suppuration and is accompanied by severe pain (alveolalgia) and foul odor. (Dorland, 28th ed)
Mupirocin
Thymol
Smear Layer
Adherent debris produced when cutting the enamel or dentin in cavity preparation. It is about 1 micron thick and its composition reflects the underlying dentin, although different quantities and qualities of smear layer can be produced by the various instrumentation techniques. Its function is presumed to be protective, as it lowers dentin permeability. However, it masks the underlying dentin and interferes with attempts to bond dental material to the dentin.
1-Propanol
Vascular Access Devices
Dental Materials
Streptococcus sobrinus
Administration, Topical
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
Equipment Contamination
Umbilical Cord
Toothbrushing
Dental Caries
Dental Leakage
Triclosan
Iodophors
Enterococcus faecalis
Polyhydroxyethyl Methacrylate
Root Canal Filling Materials
Skin Care
Maintenance of the hygienic state of the skin under optimal conditions of cleanliness and comfort. Effective in skin care are proper washing, bathing, cleansing, and the use of soaps, detergents, oils, etc. In various disease states, therapeutic and protective solutions and ointments are useful. The care of the skin is particularly important in various occupations, in exposure to sunlight, in neonates, and in PRESSURE ULCER.
Tooth Demineralization
Oral Hygiene
Salivary contribution to exhaled nitric oxide. (1/615)
Dietary and metabolic nitrate is distributed from the blood to the saliva by active uptake in the salivary glands, and is reduced to nitrite in the oral cavity by the action of certain bacteria. Since it has been reported that nitric oxide may be formed nonenzymatically from nitrite this study aimed to determine whether salivary nitrite could influence measurements of exhaled NO. Ten healthy subjects fasted overnight and ingested 400 mg potassium nitrate, equivalent to approximately 200 g spinach. Exhaled NO and nasal NO were regularly measured with a chemiluminescence technique up to 3 h after the ingestion. Measurements of exhaled NO were performed with a single-breath procedure, standardized to a 20-s exhalation, at a flow of 0.15 L x s(-1), and oral pressure of 8-10 cmH2O. Values of NO were registered as NO release rate (pmol x s(-1)) during the plateau of exhalation. Exhaled NO increased steadily over time after nitrate load and a maximum was seen at 120 min (77.0+/-15.2 versus 31.2+/-3.0 pmol x s(-1), p<0.01), whereas no increase was detected in nasal NO levels. Salivary nitrite concentrations increased in parallel; at 120 min there was a four-fold increase compared with baseline (1.56+/-0.44 versus 0.37+/-0.09 mM, p<0.05). The nitrite-reducing conditions in the oral cavity were also manipulated by the use of different mouthwash procedures. The antibacterial agent chlorhexidine acetate (0.2%) decreased NO release by almost 50% (p<0.01) 90 min after nitrate loading and reduced the preload control levels by close to 30% (p<0.05). Sodium bicarbonate (10%) also reduced exhaled NO levels, but to a somewhat lesser extent than chlorhexidine acetate. In conclusion, salivary nitric oxide formation contributes to nitric oxide in exhaled air and a large intake of nitrate-rich foods before the investigation might be misinterpreted as an elevated inflammatory activity in the airways. This potential source of error and the means for avoiding it should be considered in the development of a future standardized method for measurements of exhaled nitric oxide. (+info)Disinfection of upper gastrointestinal fibreoptic endoscopy equipment: an evaluation of a cetrimide chlorhexidine solution and glutaraldehyde. (2/615)
There is little information available on the bacteriological contamination of upper gastrointestinal fibreoptic endoscopes during routine use and the effects of 'disinfecting solutions'. A bacteriological evaluation was therefore made of cleaning an endoscope and its ancillary equipment with (1) water, (2) an aqueous solution of 1% cetrimide with 0.1% chlorhexidine, and (3) activated aqueous 2% glutaraldehyde. All equipment, but particularly the endoscope itself, was found to be heavily contaminated after use with a wide variety of organisms of which 53% were Gram positive. Cleaning the endoscope and ancillary equipment with water and the cetrimide/chlorhexidine solution alone or in combination was inadequate to produce disinfection but immersion in glutaraldehyde for two minutes consistently produced sterile cultures with our sampling technique. A rapid and simple method for disinfection of endoscopic equipment is therefore recommended and we think this is especially suitable for busy endoscopy units. (+info)Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine. (3/615)
Matrix metalloproteinases (MMPs) are a host cell-derived proteolytic enzyme family which plays a major role in tissue-destructive inflammatory diseases such as periodontitis. The aim of the present study was to evaluate the inhibitory effect of chlorhexidine (CHX) on MMP-2 (gelatinase A), MMP-9 (gelatinase B), and MMP-8 (collagenase 2) activity. Heat-denatured type I collagen (gelatin) was incubated with pure human MMP-2 or -9 activated with p-aminophenylmercuric acetate (APMA), and the proteolytic degradation of gelatin was monitored by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Coomassie blue staining. The effect of CHX on MMP-8 activity was also studied with a cellular model addressing the ability of phorbol myristate acetate (PMA)-triggered human peripheral blood neutrophils (polymorphonuclear leukocytes [PMNs]) to degrade native type I collagen. CHX inhibited the activities of both gelatinases (A and B), but MMP-2 appeared to be more sensitive than MMP-9. Adding calcium chloride to the assay mixtures almost completely prevented the inhibition of MMP-9 activity by CHX, while the inhibition of MMP-2 activity could be reversed only when CHX was used at a low concentration. This observation suggests that CHX may act via a cation-chelating mechanism. CHX dose-dependently inhibited collagenolytic activity of MMP-8 released by PMA-triggered PMNs. MMP-8 without APMA activation was inhibited clearly more efficiently than APMA-activated MMP-8. Our study suggests that the direct inhibition of the MMPs' activities by CHX may represent a new valuable effect of this antimicrobial agent and explains, at least in part, the beneficial effects of CHX in the treatment of periodontitis. (+info)Antimicrobial susceptibility and composition of microcosm dental plaques supplemented with sucrose. (4/615)
The aims of this study were to evaluate the effects of repeated chlorhexidine gluconate (CHG) pulsing on the viability and bacterial composition of microcosm dental plaques derived from human saliva. The biofilms were grown on bovine enamel discs in a constant-depth film fermentor fed with an artificial saliva which was supplemented thrice daily with sucrose. The microcosm plaques had total viable anaerobic counts of 5 x 10(8) CFU per mm2 and consisted of 12% Actinomyces spp., 85% streptococci, and 0.2% Veillonella spp. When pulsed twice daily with 0.2% CHG, there was an immediate 1.3-log10 reduction in the total viable (anaerobic) count. However, as pulsing continued, the viable counts recovered, and after 4 days, the anaerobic count reached its pre-CHG-pulsing level, although the bacterial composition of the biofilms had changed. The results of this study show that twice-daily pulsing with 0.2% CHG over a 4-day period was ineffective at reducing the total anaerobic viable count of the biofilms but did alter their bacterial composition. (+info)Can group B streptococci cause symptomatic vaginitis? (5/615)
BACKGROUND: Maternal cervicovaginal colonization with Lancefield group B streptococci (GBS) is an important risk factor for neonatal morbidity and mortality. About 15% of women are carriers of GBS. Usually, they are asymptomatic. CASES: We describe two patients with symptomatic vaginitis for which no apparent cause was found. Both patients were heavily colonized with GBS. After antibiotic treatment, both became asymptomatic and culture negative, but after recolonization with GBS, symptoms resumed. This phenomenon was repeatedly observed. After emergence of resistance to antibiotics, local application of chlorhexidine appeared to be the only useful treatment. CONCLUSION: We hypothesize that GBS-vaginitis may be a possible disease entity. Although at present it is not clear why some patients become symptomatic, we speculate that the immunologic response is somehow selectively hampered in such patients. (+info)A clinical comparison of the efficacy and efficiency of two professional prophylaxis procedures in orthodontic patients. (6/615)
This study compared the efficacy and efficiency of two professional prophylaxis procedures in orthodontic patients performing different oral hygiene regimens: the air powder polishing system (APP), and the rubber cup and pumice (RCP) technique. Sixty-two patients were divided into two groups: group I included 40 subjects who did not use any chlorhexidine mouthwash and group II comprised 22 subjects who regularly rinsed with a chlorhexidine mouthwash (at a 0.12 per cent concentration) and showed increased tooth staining. Using a split-mouth experimental design, the buccal and lingual tooth surfaces were cleaned in half of the mouth by the APP and in the opposite half by the RCP technique. Tooth surfaces were scored before (PRE) and after (POST) the experimental procedures for the plaque index (PI), and for the presence of tooth staining. In addition, the treatment time required by each procedure was recorded. In test group I, significant reductions in the PI after APP and RCP were observed. Likewise, in test group II, both procedures significantly reduced the baseline PI values. In both experimental groups, the percentage of stained sites significantly decreased after APP and RCP, but in test group II, APP seemed to be more effective than RCP. In addition, APP required significantly less time than RCP to remove dental plaque and staining. These data show that both professional prophylaxis procedures are effective in orthodontic patients, with APP being the most time-efficient technique and the most effective method for removal of tooth staining. (+info)N-acetylneuraminic acid transport by Streptococcus oralis strain AR3. (7/615)
Streptococcus oralis has emerged as one of the most important organisms of the viridans streptococcus group in terms of infections and is recognised as an agent of infective endocarditis and, in immunocompromised patients, septicaemia. The mechanisms by which this organism proliferates in vivo are unknown. However, host-derived sialic acids -- including N-acetylneuraminic acid (NeuNAc) which is present in serum and cell-associated glycoproteins -- are a potential source of fermentable carbohydrate for bacterial proliferation, especially for sialidase-producing bacteria, including S. oralis. To further elucidate the role of NeuNAc in supporting growth, this study determined the ability of S. oralis strain AR3 (isolated from a patient with infective endocarditis) to transport NeuNAc and characterised the transport system. The transport of [14C]-labelled NeuNAc into S. oralis was monitored and this transport system was induced by growth of the bacteria in the presence of the N-acetylated sugars NeuNAc, N-acetylglucosamine and N-acetylmannosamine. The transport system followed typical Michaelis-Menten kinetics, with a Km of 21.0 microM and a Vmax of 2.65 nmoles of NeuNAc transported/min/mg of dry cell mass. NeuNAc transport was inhibited by the presence of exogenous N-glycolylneuraminic acid, a related sialic acid. Chlorhexidine, NaF and 2,4-dinitrophenol were potent inhibitors of the transport system, suggesting that the uptake of NeuNAc occurs via a proton motive force-dependent permease system. This is the first report of the mechanism by which NeuNAc transport occurs in pathogenic streptococci. This transport process may have relevance to the acquisition of a source of fermentable carbohydrate and thus bacterial proliferation in vivo. (+info)Chlorhexidine and chondrolysis in the knee. (8/615)
We have summarised the clinical and pathological changes in the knees of three patients in whom aqueous chlorhexidine 0.02% had been used as the irrigation solution during arthroscopically-assisted reconstruction of the anterior cruciate ligament. Even very dilute solutions of chlorhexidine can cause marked chondrolysis of articular cartilage leading to severe permanent damage to the knee. Irrigation solutions should be checked carefully to ensure that their composition is appropriate to the procedure being carried out. Exposure of articular cartilage to chlorhexidine should be avoided. (+info)
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Reappraisal of routine oral care with chlorhexidine gluconate for patients receiving mechanical ventilation: Systematic review...
Effectiveness of oral chlorhexidine on nosocomial pneumonia, causative micro-organisms and mortality in critically ill patients...
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Effect of Smear Layer and Chlorhexidine Treatment on the Adhesion of Enterococcus faecalis to Bovine Dentin<...
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Index of oral health and dental articles
Chlorhexidine • Christian Medical and Dental Fellowship of Australia • Christian Medical and Dental Society • Church and Dwight ...
Oral hygiene
ChlorhexidineEdit. Chlorhexidine gluconate is an antiseptic mouthrinse that should only be used in two-week time periods due to ... There are three commonly used kinds of mouthwash: saline (salty water), essential oils (Listerine, etc.), and chlorhexidine ... Van Leeuwen M, Slot D, Van der Weijden G. "Essential oils compared to chlorhexidine with respect to plaque and parameters of ... Strydonck DA, Slot DE, Velden U, Weijden F. "Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining ...
WHO Surgical Safety Checklist
... use of chlorhexidine soap; use of sterile PPE and barrier drapes; and daily inspection for possible removal). The checklist ...
Virucide
Chlorhexidine - mainly against enveloped viruses. Povidone-iodine (PVP-I), "high potency for virucidal activity has been ...
Tonsil stones
Chlorhexidine may also be tried. Surgical treatment may include partial or complete tonsil removal. Up to 10% of people have ... Chlorhexidine may also be tried. Surgical treatment may include partial or complete tonsil removal. Some people are able to ...
Octenidine dihydrochloride
Comparison between octenidine and chlorhexidine determined by the suspension test after 5 minutes of exposure.. Effective ... compared to chlorhexidine after 15 min.[8] Wound irrigation with octenidine has caused severe complications in dogs,[9] aseptic ... Octenidine preparations are less expensive than chlorhexidine and no resistance had been observed as of 2007.[2] They may ... It is a substitute for chlorhexidine, with respect to its slow action and concerns about the carcinogenic impurity 4- ...
Picloxydine
It is structurally similar to chlorhexidine. Obikili AG, Oji EO, Shonekan RO, Otti P (1988). "A double-blind comparison of ...
Chronic periodontitis
Chlorhexidine impregnated chips are also available. Hydrogen peroxide is a naturally occurring antimicrobial that can be ... and chlorhexidine. Adjunctive local therapy generally reduced PD levels....Whether such improvements, even if statistically ...
Mouthwash
Chlorhexidine mouthwash can also cause taste disturbance or alteration. Chlorhexidine is rarely associated with other issues ... demonstrated that a chlorhexidine compound could prevent the build-up of dental plaque. The reason for chlorhexidine's ... chlorhexidine mouthrinse. Chlorhexidine mouthrinses increase staining score of teeth over a period of time. However, many ... "Chlorhexidine alcohol base mouthrinse versus Chlorhexidine formaldehyde base mouthrinse efficacy on plaque control: double ...
Endodontic therapy
Certain irrigants, such as sodium hypochlorite and chlorhexidine, have proved to be effective antimicrobials in vitro[20] and ...
Childbirth
Evidence of benefit with chlorhexidine is lacking. A decreased risk is found with providone-iodine when a cesarean section is ... Another effort to prevent infection has been the use of the antiseptic chlorhexidine or providone-iodine solution in the vagina ... Lumbiganon P, Thinkhamrop J, Thinkhamrop B, Tolosa JE (September 2014). "Vaginal chlorhexidine during labour for preventing ...
Cystoscopy
Often, skin preparation is performed with chlorhexidine. Patients receiving a ureteroscopy may receive a spinal or general ...
Polyacrylic acid
PAA may inactivate the antiseptic chlorhexidine gluconate. The neutralized polyacrylic acid gels are suitable to obtain ... Kaiser, Nancy; Klein, Dan; Karanja, Peter; Greten, Zachariah; Newman, Jerry (2009). "Inactivation of chlorhexidine gluconate on ...
Streptococcus sobrinus
"Nanoparticle-Encapsulated Chlorhexidine against Oral Bacterial Biofilms". PLOS ONE. 9 (8): e103234. Bibcode:2014PLoSO...9j3234S ...
Peter Pronovost
Clean the patient's skin with chlorhexidine antiseptic. Put sterile drapes over the entire patient. Wear a sterile mask, hat, ...
Alexidine
"Antimicrobial substantivity of alexidine and chlorhexidine in dentin". J Endod. 39 (11): 1413-5. doi:10.1016/j.joen.2013.07.038 ...
Bad breath
Cetylpyridinium chloride and chlorhexidine can temporarily stain teeth. If gum disease and cavities are present, it is ... Tentative evidence supports the use of mouthwash containing chlorhexidine or cetylpyridinium chloride. While there is tentative ... Mouthwashes often contain antibacterial agents including cetylpyridinium chloride, chlorhexidine, zinc gluconate, zinc chloride ...
Povidone-iodine
Chlorhexidine provides superior results with equivalent adverse events. Consequently, PVP-I has found broad application in ... There is strong evidence that chlorhexidine and denatured alcohol used to clean skin prior to surgery is better than any ... Wade RG, Burr NE, McCauley G, Bourke G, Efthimiou O (September 2020). "The Comparative Efficacy of Chlorhexidine Gluconate and ...
Dental health diets for dogs
Chlorhexidine can also reduce the amount of pre-existing plaque. Chlorhexidine is generally found on products such as dental ... Chlorhexidine is another example of a non-specific antimicrobial agent. It acts by disrupting bacterial deposition and plaque ... Davies, R.M.; Hull, P.S. (1973). "Plaque inhibition and distribution of chlorhexidine in Beagle dogs". Journal of Periodontal ... Ingredients such as polyphosphate, zinc salts, and chlorhexidine have active properties to help prevent or reduce the formation ...
Toothpaste
Chlorhexidine is another antimicrobial agent used in toothpastes, however it is more commonly added in mouthwash products. ... Slot DE, Berchier CE, Addy M, Van der Velden U, Van der Weijden GA (February 2014). "The efficacy of chlorhexidine dentifrice ... James P, Worthington HV, Parnell C, Harding M, Lamont T, Cheung A, Whelton H, Riley P (March 2017). "Chlorhexidine mouthrinse ... "Current uses of chlorhexidine for management of oral disease: a narrative review". Journal of Dentistry. 103: 103497. doi: ...
Local anesthetic
Before injection, disinfect gingival sulcus with 0.2% chlorhexidine solution. Administration of soft tissue anesthesia is ...
Delftia acidovorans
Some strains can tolerate chlorhexidine, a common surgical disinfectant. Infections of D. acidovorans can be confirmed through ... "Microscopic and Spectroscopic Analyses of Chlorhexidine Tolerance in Delftia acidovorans Biofilms". Antimicrobial Agents and ... "Microscopic and Spectroscopic Analyses of Chlorhexidine Tolerance in Delftia acidovorans Biofilms". Antimicrobial Agents and ...
Thymol
Filoche, S. K.; Soma, K.; Sissons, C. H. (2005). "Antimicrobial effects of essential oils in combination with chlorhexidine ... thymol has been found to be more effective when used in combination with chlorhexidine than when used purely by itself. Thymol ...
Denture-related stomatitis
Often an antimicrobial mouthwash such as chlorhexidine is concurrently prescribed. Possible underlying disease (diabetes, HIV) ...
Scaling and root planing
However effective, chlorhexidine gluconate is not meant for long-term use. A recent European study suggests a link between the ... Oral irrigation of the periodontal tissues may be done using chlorhexidine gluconate solution, which has high substantivity in ... They also had the patients use chlorhexidine for two months after the treatment. Another question in dental cleaning is how ... the active antibacterial ingredients in chlorhexidine gluconate infiltrate the tissue and remain active for a period of time. ...
Cutibacterium acnes
July 2012). "Efficacy of chlorhexidine gluconate ointment (Oronine H(®)) for experimentally-induced comedones". Clinical, ... and chlorhexidine gluconate. Several naturally occurring molecules and compounds are toxic to C. acnes bacteria. Some essential ...
Miswak
Chlorhexidine gluconate was also linked to serious allergic reactions, albeit rarely. The use of the miswak is frequently ... Mouthrinses containing chlorhexidine was with maximum antibacterial activity, while cetylpyridinium chloride mouthrinses were ... "Safety Alerts for Human Medical Products - Chlorhexidine Gluconate: Drug Safety Communication - Rare But Serious Allergic ... low antimicrobial activity compared to other oral disinfectants and anti-plaque agents like triclosan and chlorhexidine ...
Pulpotomy
Pulpal bleeding can be controlled by irrigation of sodium hypochlorite or chlorhexidine. The site is then covered with a pulpal ... The surface of the remaining pulp is then irrigated with bacteriocidal irrigants such as sodium hypochlorite or chlorhexidine ...
Eclabium
Brookes, Zoë L.S.; Bescos, Raul; Belfield, Louise A.; Ali, Kamran; Roberts, Anthony (2020). "Current uses of chlorhexidine for ... antimicrobial mouth rinse such as chlorhexidine, antiseptic chips/gels. When the swelling in the gums reduces it will no longer ...
Cetrimide
ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI later sold the Savlon brand OTC to ...
Chlorhexidine Effective Against Candida auris Biofilms
A combination of standard infection-prevention measures and the use of the disinfectant chlorhexidine should be used to control ... and chlorhexidine. The antiseptic chlorhexidine showed the greatest activity, "requiring ,0.02% to effectively inhibit ... A combination of standard infection prevention measures and the use of disinfectant chlorhexidine should be used to combat the ... Cite this: Chlorhexidine Effective Against Candida auris Biofilms - Medscape - Jan 12, 2017. ...
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Chlorhexidine Adoption in Nigeria
Students quickly learn that there are no easy answers to encouraging chlorhexidines greater use. To develop a plan, it is ... It was clear that chlorhexidine, a substance applied to newborns umbilical cord stumps to prevent infection, could reduce ... Chlorhexidine Adoption in Nigeria. Case Number: 5-217-255, Year Published: 2017 ... 10 million contributed by global donors and foundations to scale up the use of chlorhexidine in Nigeria. ...
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A list of US medications equivalent to Chlorhexidine Acetate is available on the Drugs.com website. ... Chlorhexidine Acetate is a medicine available in a number of countries worldwide. ... Ingredient matches for Chlorhexidine Acetate. Chlorhexidine. Chlorhexidine Acetate (BANM) is known as Chlorhexidine in the US. ... Chlorhexidine Acetate. Chlorhexidine Acetate may be available in the countries listed below. ...
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About CHLORHEXIDINE DIGLUCONATE: Chlorhexidine Digluconate is a salt of Chlorhexidine (q.v.) and gluconic acid.. Function(s): ... CHLORHEXIDINE BIGLUCONATE; CHLORHEXIDINE GLUCONATE; CHLORHEXIDINE GLUCONATE SOLUTION; COMPD. WITH D-GLUCONIC ACID; COMPD. WITH ... Synonym(s): CHLORHEXIDINE GLUCONATE; 1,1-HEXAMETHYLENE BIS (5- (P-CHLOROPHENYL) BIGUANIDE) DIGLUCONATE; ...
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A Chlorhexidine Gluconate 0.12% oral rinse for use between dental visits as part of a professional program for the treatment of ... A Chlorhexidine Gluconate 0.12% oral rinse for use between dental visits as part of a professional program for the treatment of ... 3M™ Peridex™ Chlorhexidine Gluconate 0.12% Oral Rinse is rated 5.0 out of 5 by 3. ... Chlorhexidine gluconate has years of clinical study and experience showing effective antimicrobial activity. In other words, it ...
Chlorhexidine/Chlorobutanol Biogaran - Drugs.com
A list of US medications equivalent to Chlorhexidine/Chlorobutanol Biogaran is available on the Drugs.com website. ... Chlorhexidine/Chlorobutanol Biogaran is a medicine available in a number of countries worldwide. ... Chlorhexidine. Chlorhexidine digluconate (a derivative of Chlorhexidine) is reported as an ingredient of Chlorhexidine/ ... Chlorhexidine/Chlorobutanol Biogaran may be available in the countries listed below.. Ingredient matches for Chlorhexidine/ ...
Covonia throat spray (lidocaine, chlorhexidine)
Chlorhexidine is an antiseptic and disinfectant agent that kills various bacteria, viruses and fungi that can cause throat ... Although lidocaine and chlorhexidine have been in widespread use for many years without apparently causing harm, their safety ... Covonia throat spray contains two active ingredients, lidocaine and chlorhexidine. Lidocaine is a type of medicine called a ... Covonia throat spray (lidocaine, chlorhexidine). Available over the counter from pharmacies, we explain everything you need to ...
Chlorhexidine - definition of chlorhexidine by The Free Dictionary
chlorhexidine synonyms, chlorhexidine pronunciation, chlorhexidine translation, English dictionary definition of chlorhexidine ... n an antiseptic compound used in skin cleansers, mouthwashes, etc Noun 1. chlorhexidine - a long-lasting liquid antiseptic; ... chlorhexidine. Also found in: Thesaurus, Medical, Legal, Encyclopedia, Wikipedia. chlorhexidine. (klɔːˈhɛksɪdiːn) n. ( ... 2 % Chlorhexidine Gluconate in 70 % Alcohol Solution 4 % Chlorhexidine Gluconate in 70 % Alcohol Solution 10 % Povidone Iodine ...
Chlorhexidine - Risk of Anaphylaxis
Chlorhexidine-free products are approved in New Zealand for patients with an allergy to chlorhexidine. ... use of chlorhexidine containing products was postulated to result in sensitisation to chlorhexidine1. This could lead to an ... Chlorhexidine - Risk of Anaphylaxis. Prescriber Update 34(2):22. June 2013. Severe allergic reactions including anaphylaxis ... Of the eight cases, five reported the results of a skin prick test of which four were positive for chlorhexidine sensitivity. ...
Davis 2% Chlorhexidine Shampoo
Davis Chlorhexidine Shampoo works to soothe skin irritations, cool inflamed skin and combat skin conditions that are associated ... Davis Chlorhexidine Shampoo works to soothe skin irritations, cool inflamed skin and combat skin conditions that are associated ... Ingredients: Chlorhexidine Gluconate, Ammonium Laureth Sulfate with Ethanol, pH Adjuster, Coconut Based Lathering Agent, ... Contains 2% Chlorhexidine Gluconate, which helps provide fast relief and assists in the healing process. ...
DailyMed - CHLORHEXIDINE GLUCONATE rinse
CHLORHEXIDINE GLUCONATE (UNII: MOR84MUD8E) (CHLORHEXIDINE - UNII:R4KO0DY52L) CHLORHEXIDINE GLUCONATE. 1.2 mg in 1 mL. ... Chlorhexidine gluconate product is a near neutral solution (pH range 5-7). Chlorhexidine gluconate is a salt of chlorhexidine ... Chlorhexidine gluconate oral rinse should not be used by persons who are known to be hypersensitive to chlorhexidine gluconate ... Excretion of chlorhexidine gluconate occurred primarily through the feces (~90%). Less than 1% of the chlorhexidine gluconate ...
Prescriber Checkup | CHLORHEXIDINE GLUCONATE
Prepping with Chlorhexidine | allnurses
Chlorhexidine - Wikipedia
Chlorhexidine (commonly known by the salt forms chlorhexidine gluconate and chlorhexidine digluconate (CHG) or chlorhexidine ... Chlorhexidine came into medical use in the 1950s. Chlorhexidine is available over the counter (OTC) in the United States. It is ... In animals, chlorhexidine is used for topical disinfection of wounds, and to manage skin infections. Chlorhexidine-based ... "Chlorhexidine Adverse Effects". www.poison.org. Retrieved 2018-07-04. Pubchem. "Chlorhexidine". pubchem.ncbi.nlm.nih.gov. ...
Chlorhexidine 11012
Chlorhexidine News
Comparing Chlorhexidine Concentrations in Gingivitis Comparing Chlorhexidine Concentrations in Gingivitis. Chlorhexidine rinse ... Chlorhexidine Does Not Reduce MDR Organisms in Non-ICU Hospital Areas Chlorhexidine Does Not Reduce MDR Organisms in Non-ICU ... Chlorhexidine Gel for Prevention of Alveolar Osteitis Chlorhexidine Gel for Prevention of Alveolar Osteitis. Alveolar osteitis ... Might Chlorhexidine Wipes Reduce CLABSI Risk for Cancer Patients?. Chlorhexidine wipe bathing might help reduce the risk of ...
Petition · Ban indistinct pourable chlorhexidine from hospitals · Change.org
Distinct versions of chlorhexidine (on right in image) and non-pourable applicators are already used in many hospitals without ... Indistinct chlorhexidine (circled) is easily mistaken for other colourless solutions leading to the suffering of many patients ... Patient Safe needs your help with "Ban indistinct pourable chlorhexidine from hospitals". Join Patient and 653 supporters today ... Patient Safe needs your help with "Ban indistinct pourable chlorhexidine from hospitals". Join Patient and 653 supporters today ...
Cytopathologic effects of chlorhexidine on human cells. - PubMed - NCBI
Exposure of human cells in culture to chlorhexidine at concentrations equal to or greater than 0.004% resulted in impaired ... Cytopathologic effects of chlorhexidine on human cells.. Goldschmidt P, Cogen R, Taubman S. ... Exposure of cells to 0.2% chlorhexidine for 30 seconds produced maximal suppression of protein synthesis and release of 51Cr. ... Cytopathologic[Title] AND effects[Title] AND chlorhexidine[Title] AND human[Title] AND cells[Title]. Search. ...
Chlorhexidine (Oral Route) Side Effects - Mayo Clinic
Chlorhexidine may have a bitter aftertaste. Do not rinse your mouth with water immediately after using chlorhexidine, since ... Chlorhexidine destroys the bacteria, thereby preventing the gingivitis from occurring. However, chlorhexidine does not prevent ... Information about this chlorhexidine-oral-route. Pregnancy Category. Explanation. All Trimesters. C. Animal studies have shown ... Chlorhexidine may change the way foods taste to you. Sometimes this effect may last up to 4 hours after you use the oral rinse ...
Chlorhexidine (Oral Route) Side Effects - Mayo Clinic
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. ...
chlorhexidine gluconate | MomsTeam
Trial of chlorhexidine gluconate for fungal corneal ulcers. - PubMed - NCBI
Trial of chlorhexidine gluconate for fungal corneal ulcers.. Rahman MR1, Minassian DC, Srinivasan M, Martin MJ, Johnson GJ. ... In vitro studies and a small pilot study have shown that chlorhexidine gluconate is effective. The aim was to establish the ... At 5 days the response was related to the concentration of chlorhexidine, with 0.2% giving the best results. Compared with the ... A masked randomized clinical trial of three concentrations of chlorhexidine compared with natamycin 5% was carried out in ...
Chlorhexidine Cuts Risk of Surgical Infections | Medpage Today
The chemical antiseptic chlorhexidine does a better job than povidone-iodine in reducing the risk of surgical site infections, ... In the mupirocin/chlorhexidine group, 17 of 504 patients (or 3.4%) got an S. aureus infection, compared with 32 of 413 patients ... The chemical antiseptic chlorhexidine does a better job than povidone-iodine in reducing the risk of surgical site infections, ... On the other hand, he said, the "weight of evidence" is now firmly on the side of chlorhexidine and alcohol as a preoperative ...
DOUXO Chlorhexidine Micro-emulsion Spray | 1800PetMeds
Buy DOUXO Chlorhexidine Micro-emulsion Spray and other Antibacterials from top brands at 1800PetMeds and save. Free shipping on ... DOUXO Chlorhexidine Micro-emulsion Spray Dosage:. DOUXO Chlorhexidine Micro-emulsion Spray Dosage for Cats Weight. Dosage. ... DOUXO Chlorhexidine Micro-emulsion Spray Dosage:. DOUXO Chlorhexidine Micro-emulsion Spray Dosage for Cats Weight. Dosage. ... DOUXO Chlorhexidine Micro-emulsion Spray Ingredients:. DOUXO Chlorhexidine Micro-emulsion Spray Active Ingredients Amount. ...
Chlorhexidine patch on central lines | allnurses
Our Infection Control Practitioner has approached us regarding changing the brand of chlorhexidine patch we use on all central ... Im not aware of people being sensitive to chlorhexidine. I do know that I dont like it much for an open wound!. Z ... By the way, Ive kind of noticed a trend where there is becoming a kind of hesitance to be so heavy-handed with chlorhexidine ... I work in a NICU and we commonly see patients with Chlorhexidine sensitivity/allergies. We typically see it on our older babies ...
benzocaine-chlorhexidine: uses & side-effects | PatientsLikeMe
Chlorhexidine - Substance Information - ECHA
RinseMouthwashBacteriaProducts containing chEffect of chlorhexidineAllergy to chlorhexidineGingivitisDisinfectantPovidone IodineDigluconateVaginalShampooAntiseptic chlorhexidineInfectionsAcetateSolutionUmbilical cordAvoid while using chlorheGroup treated with chlorhexidineContain Chlorhexidine gluconateContains chlorhexidine gluconateGums0.05Antimicrobial activityForm of chlorhexidineOverdose of chlorhexidineApplication of chlorhexidineRisk of AnaphylaxisPreoperativePercent chlorhexidineGluconate mouthwashesRinsesOralAlcoholHealthcareSensitivityMouthwashesAntisepsis2018ConcentrationsEfficacyMorbidity and mortaInfectionEthanolProcedureIngredientsAntibacterialAnaphylaxisAllergic reactionsIodine
Rinse41
- Extrinsic tooth staining occurs when chlorhexidine rinse has been used for 4 weeks or longer. (wikipedia.org)
- A Chlorhexidine Gluconate 0.12% oral rinse for use between dental visits as part of a professional program for the treatment of gingivitis. (3m.com)
- Three months after Peridex oral rinse use was discontinued, the number of bacteria in plaque had returned to baseline levels and resistance of plaque bacteria to chlorhexidine gluconate was equal to that at baseline. (3m.com)
- Patients with a known sensitivity to chlorhexidine gluconate should not use Peridex oral rinse. (3m.com)
- The objective of this study was to establish whether addition of a 2% chlorhexidine as final rinse to a conventional treatment protocol decreases the postoperative discomfort after single-visit endodontic treatment. (thefreedictionary.com)
- Chlorhexidine gluconate oral rinse provides antimicrobial activity during oral rinsing. (nih.gov)
- Use of chlorhexidine gluconate oral rinse in a six-month clinical study did not result in any significant changes in bacterial resistance, overgrowth of potentially opportunistic organisms or other adverse changes in the oral microbial ecosystem. (nih.gov)
- Pharmacokinetic studies with chlorhexidine gluconate oral rinse indicate approximately 30% of the active ingredient, chlorhexidine gluconate, is retained in the oral cavity following rinsing. (nih.gov)
- Chlorhexidine gluconate oral rinse is indicated for use between dental visits as part of a professional program for the treatment of gingivitis as characterized by redness and swelling of the gingivae, including gingival bleeding upon probing. (nih.gov)
- Chlorhexidine gluconate oral rinse has not been tested among patients with acute necrotizing ulcerative gingivitis (ANUG). (nih.gov)
- Chlorhexidine gluconate oral rinse should not be used by persons who are known to be hypersensitive to chlorhexidine gluconate or other formula ingredients. (nih.gov)
- The effect of chlorhexidine gluconate oral rinse on periodontitis has not been determined. (nih.gov)
- An increase in supragingival calculus was noted in clinical testing in chlorhexidine gluconate oral rinse users compared with control users. (nih.gov)
- It is not known if chlorhexidine gluconate oral rinse use results in an increase in subgingival calculus. (nih.gov)
- 1. For patients having coexisting gingivitis and periodontitis, the presence or absence of gingival inflammation following treatment with chlorhexidine gluconate oral rinse should not be used as a major indicator of underlying periodontitis. (nih.gov)
- 2. Chlorhexidine gluconate oral rinse can cause staining of oral surfaces, such as tooth surfaces, restorations, and the dorsum of the tongue. (nih.gov)
- 15% of chlorhexidine gluconate oral rinse users developed what was judged to be heavy stain, compared to 1% of control users after six months. (nih.gov)
- Chlorhexidine oral rinse should be used after you have brushed and flossed your teeth. (mayoclinic.org)
- I've used Chlorhexidine Rinse 0.13 with Zine do you have this product? (1800petmeds.com)
- CHLORHEXIDINE (klor HEX i deen) oral rinse is used to treat gingivitis. (cvs.com)
- Chlorhexidine gluconate oral rinse contains a chemical called chlorhexidine, which destroys harmful mouth bacteria, treats gingivitis, and promotes the healing of inflamed gums. (colgate.com)
- When you rinse with chlorhexidine gluconate mouthwash, the active ingredient chlorhexidine works to destroy harmful mouth bacteria, even after you spit. (colgate.com)
- If you are ready to take steps towards gum health, chlorhexidine gluconate oral rinse could be helpful in improving your oral care routine. (colgate.com)
- To decrease the effect on how food tastes, eat first, followed by tooth brushing and then chlorhexidine rinse. (webmd.com)
- Rinse the skin before applying chlorhexidine topical. (wellspan.org)
- The clean mint flavor of our chlorhexidine gluconate oral rinse tastes less medicinal than other brands, encouraging patient compliance. (philips.cz)
- Prescription-strength chlorhexidine gluconate rinse (16 oz. bottle). (philips.cz)
- Rinse skin area to be treated with Chlorhexidine Solution. (lambertvetsupply.com)
- Chlorhexidine gluconate oral rinse is used to treat gingivitis (swelling, redness, bleeding gums). (wellspan.org)
- Chlorhexidine gluconate oral rinse is not for treating all types of gingivitis. (wellspan.org)
- Rinse your mouth with chlorhexidine gluconate twice daily after brushing your teeth. (wellspan.org)
- Do not rinse your mouth with water or other mouthwashes right after using chlorhexidine gluconate. (wellspan.org)
- Chlorhexidine Gluconate Oral Rinse: What Is It? (colgate.com)
- Chlorhexidine gluconate oral rinse is an antimicrobial rinse often used to treat the beginning stages of gum disease . (colgate.com)
- Chlorhexidine gluconate 0.12 percent is the generic name for an oral rinse that has the ability to reduce the amount of bacteria in your mouth. (colgate.com)
- If your gums do not respond as well as your dentist would like or if you have a medical condition like diabetes that interferes with healing, he or she may give you a prescription for chlorhexidine gluconate oral rinse to use as a part of your home-care regiment. (colgate.com)
- Rinsing as directed with a chlorhexidine gluconate rinse reduces the amount of harmful bacteria and plaque in your mouth - giving your gum tissue a chance to heal and return to its normal, healthy state. (colgate.com)
- As with any medication, you should carefully follow your dentist's instructions on how and when to use a chlorhexidine gluconate rinse. (colgate.com)
- But if you happen to have a stubborn case of gingivitis, a chlorhexidine gluconate oral rinse may be just what your dentist orders to get your gums back to pink again. (colgate.com)
- ProDenRx 0.12% chlorhexidine rinse is effective is fighting against gingivitis. (dentalproductshopper.com)
- Chlorhexidine gluconate is also available as a prescription oral rinse solution to treat gingivitis. (fda.gov)
Mouthwash28
- Significant improvements were observed in all efficacy measures, MGI, MQH and GBI, from baseline to the end of trial at day 14 for both the polyherbal and chlorhexidine mouthwash groups. (thefreedictionary.com)
- University of Plymouth) The first study looking at the effect of chlorhexidine mouthwash on the entire oral microbiome has found its use significantly increases the abundance of lactate-producing bacteria that lower saliva pH, and may increase the risk of tooth damage. (medworm.com)
- gel (Lidex), anti-inflammatory amlexanox paste (Aphthasol), or chlorhexidine gluconate (Peridex) mouthwash. (nih.gov)
- combination mouthwash seems to work as effectively as chlorhexidine mouthwash. (nih.gov)
- a gargle 3 times daily in addition to chlorhexidine mouthwash and fluconazole for 14 days. (nih.gov)
- If you have been prescribed chlorhexidine gluconate mouthwash, chances are your dentist has told you that you have a mild form of gum disease called gingivitis. (colgate.com)
- However, according to the Mayo Clinic , you shouldn't look to chlorhexidine gluconate mouthwash to fully treat periodontitis , a more advanced form of gum disease. (colgate.com)
- Chlorhexidine gluconate mouthwash has a few possible side effects, like a change in taste, an increase in tartar build-up, and staining of the teeth, gums, and dental appliances. (colgate.com)
- Only use chlorhexidine gluconate mouthwash if your physician or dentist prescribes it. (colgate.com)
- Though chlorhexidine gluconate mouthwash is effective at killing mouth bacteria in mild cases of gum disease, it's not a substitute for regular brushing and flossing for total oral health. (colgate.com)
- Numerous studies have shown that a mouthwash containing chlorhexidine has a powerful antimicrobial effect on saliva microflora and bacterial plaque. (medindia.net)
- In 2006, the British Society for Antimicrobial Chemotherapy (BSAC) recommended a single mouthwash with 0.2 percent chlorhexidine (CHX) (10 ml for 1 minute) before the carrying out of dental procedures associated with bacteraemia in patients at risk. (medindia.net)
- Yet, given its low cost and the absence of adverse reactions and complications, we would recommend a mouthwash with chlorhexidine before a procedure of this type is carried out," concluded the UPV/EHU's research group. (medindia.net)
- After using chlorhexidine, wait at least 30 minutes before rinsing your mouth with water or mouthwash, brushing your teeth , eating, or drinking. (webmd.com)
- What conditions does Chlorhexidine Gluconate Mouthwash treat? (webmd.com)
- List Chlorhexidine Gluconate Mouthwash side effects by likelihood and severity. (webmd.com)
- What should I know regarding pregnancy, nursing and administering Chlorhexidine Gluconate Mouthwash to children or the elderly? (webmd.com)
- Burkholderia lata infections from intrinsically contaminated chlorhexidine Mouthwash, Australia, 2016. (springer.com)
- Chlorhexidine gluconate is a germicidal mouthwash that reduces bacteria in the mouth. (wellspan.org)
- With Curasept ADS (antidiscolouration system), we finally have a chlorhexidine based mouthwash without any of the side effects. (medicalsearch.com.au)
- June 3, 2020 -- In a new study, high amounts of SARS-CoV-2 were detected in the saliva of patients for days after infection, but rinsing with chlorhexidine mouthwash reduced the viral load in saliva for a short time. (drbicuspid.com)
- The viral load in the saliva decreased transiently for two hours after using the chlorhexidine mouthwash," wrote the authors, led by Jin Gu Yoon, MD, PhD, of the Division of Infectious Diseases at Korea University College of Medicine in Seoul. (drbicuspid.com)
- Other clinicians have supported using two back-to-back 30-second rinses of chlorhexidine mouthwash to reduce the salivary load of the novel coronavirus. (drbicuspid.com)
- This study shows that chlorhexidine mouthwash may be a good option, according to the authors. (drbicuspid.com)
- On days 3 and 6 of their hospital stay, the patients gargled with 15 mL of 12% chlorhexidine gluconate solution mouthwash for 30 seconds after baseline sampling. (drbicuspid.com)
- Chlorhexidine mouthwash could be beneficial in controlling droplet transmission in addition to mask wearing and hand washing," they concluded. (drbicuspid.com)
- Chlorhexidine gluconate is also available as a prescription mouthwash to treat gingivitis and as a prescription oral chip to treat periodontal disease. (fda.gov)
- Chlorhexidine Mouthwash Mint containing Chlorhexidine Gluconate is used to treat gingivitis (swelling, redness, and bleeding of the gums). (hotukdeals.com)
Bacteria12
- Chlorhexidine is an antiseptic and disinfectant agent that kills various bacteria, viruses and fungi that can cause throat infections. (netdoctor.co.uk)
- Davis Chlorhexidine Shampoo works to soothe skin irritations, cool inflamed skin and combat skin conditions that are associated with bacteria and a wide range of microorganisms. (petedge.com)
- Chlorhexidine destroys the bacteria, thereby preventing the gingivitis from occurring. (mayoclinic.org)
- Chlorhexidine Solution is an antiseptic and antimicrobial disinfectant that provides fast-acting activity against a wide range of microorganisms, especially against those commonly found on the skin, such as bacteria, fungi, ringworm and yeast. (revivalanimal.com)
- I now use the Maximum Chlorhexidine Shampoo every other week to ensure any bacteria is removed, using both products, your best friend, will feel much better and be happy! (jefferspet.com)
- Chlorhexidine gluconate, a topical antiseptic solution, is effective against a wide spectrum of gram-positive and gram-negative bacteria, including MRSA. (aacn.org)
- Chlorhexidine is an antiseptic that fights bacteria. (wellspan.org)
- This Chlorhexidine Gluconate Solution provides a wide range of antiseptic and antimicrobial protection against skin bacteria, fungi, ringworm and yeast. (qcsupply.com)
- Chlorhexidine is a broad-spectrum antiseptic which is effective against Gram-positive and Gram-negative bacteria on the skin and is widely used to reduce the risk of bacterial infection. (hsa.gov.sg)
- Chlorhexidine gluconate is mainly available in OTC products to clean and prepare the skin before surgery and before injections in order to help reduce bacteria that potentially can cause skin infections. (fda.gov)
- Davis Chlorhexidine Spray with 4% Chlorhexidine Gluconate is a maximum strength antiseptic spray for skin conditions caused by bacteria and/or yeast. (medi-vet.com)
- CHLORHEXIDINE DISINFECTANT is an EPA-registered disinfectant that works against at least 60 different bacteria, fungi, yeasts, and viruses. (jedds.com)
Products containing ch6
- Healthcare professionals are encouraged to report all anaphylactic reactions to products containing chlorhexidine to CARM. (medsafe.govt.nz)
- Anaphylaxis, as well serious allergic reactions, have been reported during postmarketing use with dental products containing chlorhexidine. (nih.gov)
- This review was conducted following recent international safety alerts regarding serious allergic reactions reported with antiseptic products containing chlorhexidine. (hsa.gov.sg)
- In February 2017, US FDA issued a safety communication regarding serious allergic reactions with skin antiseptic products containing chlorhexidine gluconate. (hsa.gov.sg)
- The U.S. Food and Drug Administration (FDA) is warning that rare but serious allergic reactions have been reported with the widely used skin antiseptic products containing chlorhexidine gluconate. (fda.gov)
- As a result, we are requesting the manufacturers of over-the-counter (OTC) antiseptic products containing chlorhexidine gluconate to add a warning about this risk to the Drug Facts labels . (fda.gov)
Effect of chlorhexidine4
- Hence, to enhance the antiplaque effect of chlorhexidine, "it seems best that the interval between toothbrushing and rinsing with CHX [chlorhexidine] be more than 30 minutes, cautiously close to 2 hours after brushing. (wikipedia.org)
- We report a biocidal zombie effect of chlorhexidine, a wide-scope biocidal agent commonly used in disinfectant and antiseptic formulations. (nih.gov)
- Studies have shown that alcohol provides no extra benefit to the antiplaque effect of chlorhexidine. (medicalsearch.com.au)
- All these advantages without reducing the antiplaque effect of chlorhexidine. (medicalsearch.com.au)
Allergy to chlorhexidine4
- If healthcare professionals suspect a patient has an allergy to chlorhexidine, an alternative product should be used. (medsafe.govt.nz)
- Chlorhexidine-free products are approved in New Zealand for patients with an allergy to chlorhexidine. (medsafe.govt.nz)
- They also reminded healthcare professionals that chlorhexidine is known to induce hypersensitivity, and that an alternative product should be used if they suspected a patient had an allergy to chlorhexidine. (hsa.gov.sg)
- Consider using alternative antiseptics such as povidone-iodine, alcohols, benzalkonium chloride, benzethonium chloride, or parachlorometaxylenol (PCMX) when any previous allergy to chlorhexidine gluconate is documented or suspected. (fda.gov)
Gingivitis4
- Using chlorhexidine as a supplement to everyday mechanical oral hygiene procedures for 4 to 6 weeks and 6 months leads to a moderate reduction in gingivitis compared to placebo, control or mechanical oral hygiene alone. (wikipedia.org)
- Chlorhexidine is used to treat gingivitis. (mayoclinic.org)
- This warning is currently present in the US labelling for prescription chlorhexidine gluconate mouthwashes for treatment of gingivitis and prescription oral chips used for periodontal disease. (hsa.gov.sg)
- Chlorhexidine(Peridex and PerioGard) generic Surgiscrub is a chemical antiseptic, prescribed for gingivitis, cleansing skin and wound areas. (medindia.net)
Disinfectant5
- Chlorhexidine (commonly known by the salt forms chlorhexidine gluconate and chlorhexidine digluconate (CHG) or chlorhexidine acetate), is a disinfectant and antiseptic that is used for skin disinfection before surgery and to sterilize surgical instruments. (wikipedia.org)
- A combination of standard infection prevention measures and the use of disinfectant chlorhexidine should be used to combat the potential spread of Candida auris in hospital environments, according to a study published online January 11 in Emerging Infectious Diseases . (medscape.com)
- The use of chlorhexidine reduces residual skin organisms as well as inhibits their rebound growth and has been demonstrated to reduce catheter-associated bloodstream infections in comparison to other skin disinfectant products such as povidone-iodine. (clinicaltrials.gov)
- Oronine H ® ointment, which contains chlorhexidine gluconate as its active component, is a well known disinfectant, and has been widely used for treatment of acne in Japan. (dovepress.com)
- NOTE: Chlorhexidine Disinfectant is a generic form of the Nolvasan liquid. (jedds.com)
Povidone Iodine17
- 2 % Chlorhexidine Gluconate in 70 % Alcohol Solution 4 % Chlorhexidine Gluconate in 70 % Alcohol Solution 10 % Povidone Iodine in Alcohol Solution 10 % Povidone Iodine Solution Plastic Bottles available in sizes between 50ml to 500ml. (thefreedictionary.com)
- University of Leeds) New analysis by the University of Leeds and the University of Bern of more than 14,000 operations has found that using alcoholic chlorhexidine gluconate (CHG) halves the risk of infection in certain types of surgery when compared to the more commonly used povidone-iodine (PVI). (medworm.com)
- The chemical antiseptic chlorhexidine does a better job than povidone-iodine in reducing the risk of surgical site infections, even in carriers of Staphylococcus aureus , according to two new randomized studies. (medpagetoday.com)
- Researchers in the U.S. found that chlorhexidine and alcohol, used for preoperative skin cleansing, reduced infections by 41% compared with povidone-iodine. (medpagetoday.com)
- The U.S. researchers randomly assigned 849 surgical patients, scheduled for clean-contaminated surgery in six hospitals, to have either a chlorhexidine/alcohol scrub or a scrub and paint with povidone-iodine, according to Rabih Darouiche, MD, of Baylor College of Medicine in Houston, and colleagues. (medpagetoday.com)
- Overall, the researchers found, the rate of infection was 9.5% in the chlorhexidine group, compared with 16.1% in the povidone-iodine group. (medpagetoday.com)
- But there was no difference when it came to organ-space infections, where the rate was 4.4% in the chlorhexidine group and 4.5% in the povidone/iodine group. (medpagetoday.com)
- Chlorhexidine-Alcohol Compared With Povidone-Iodine for Surg. (lww.com)
- Chlorhexidine gluconate used for central venous catheter (CVC) site cleansing can reduce the risk of bloodstream infections by 49% compared with povidone-iodine, according to the results of a meta-analysis reported in the June 4 issue of the Annals of Internal Medicine [Ann Intern Med. (oley.org)
- In patients whose catheter sites were disinfected with chlorhexidine gluconate, about 1% developed bloodstream infections, as opposed to 2% for those whose catheters were disinfected with povidone-iodine. (oley.org)
- From this data the authors conclude that chlorhexidine gluconate solution is significantly more effective than povidone-iodine solution for preventing vascular catheter-related infections. (oley.org)
- They estimate that for every 1000 catheter sites disinfected with chlorhexidine gluconate rather than povidone-iodine, 71 episodes of catheter colonization and 11 episodes of catheter-related blood stream infection (CRBSI) would be prevented. (oley.org)
- First, blood, serum, and other protein-rich biomaterials can deactivate the microbicidal effect of povidone-iodine but not chlorhexidine gluconate. (oley.org)
- Second, chlorhexidine gluconate has a much longer active antimicrobial suppression than povidone-iodine. (oley.org)
- Third, chlorhexidine gluconate has been proven better than povidone-iodine at reducing colony counts of coagulase-negative staphylococci. (oley.org)
- the author's report chlorhexidine gluconate costs approximately $0.92 for a quantity sufficient to prepare an insertion site for a CVC, versus $0.41 for a similar quantity of povidone-iodine. (oley.org)
- Randomized clinical trial of preoperative skin antisepsis with chlorhexidine gluconate or povidone-iodine. (cambridge.org)
Digluconate2
Vaginal2
- Whether vaginal preparation with chlorhexidine with 4% alcohol would have the same beneficial effect has not been studied in a systematic manner. (thefreedictionary.com)
- The PREPS pilot trial was developed to assess the feasibility of a randomized controlled trial of vaginal cleansing with chlorhexidine before cesarean section, to reduce infectious morbidity. (medworm.com)
Shampoo8
- Need directions for using Douxo Chlorhexidine Microemulsion Spray as opposed to Chlorhexidine Shampoo by Douxo. (1800petmeds.com)
- I purchased the Maximum Chlorhexidine Shampoo and used this in conjunction with this product and it totally cleared up every spot he had. (jefferspet.com)
- For best results and for added residual activity, use in conjunction with Davis Chlorhexidine Shampoo or Davis Maximum Chlorhexidine Shampoo. (medi-vet.com)
- Sogeval Chlorhexidine 4% HC Shampoo is a medicated shampoo that treats select dermatological conditions in cats, dogs, and horses. (entirelypets.com)
- Specifically, the shampoo is effective against skin conditions that are responsive to chlorhexidine and hydrocortisone, which act as antiseptic and anti-inflammatory agents to combat infections, hot spots, and more. (entirelypets.com)
- Sogeval Chlorhexidine 4% HC Shampoo also works to clean your animal's skin and coat thoroughly while removing foul odors and debris. (entirelypets.com)
- Apply and lather Chlorhexidine 4% HC Shampoo over the entire body, allowing for 5 to 10 minutes of contact time. (entirelypets.com)
- Our latest M.E.D. shampoo features 3% Chlorhexidine Gluconate as its powerful antimicrobial agent. (bestshotpet.com)
Antiseptic chlorhexidine1
- Interventions that aim to reduce neonatal mortality through umbilical cord cleansing with antiseptic chlorhexidine solution may not be effective in African settings. (thefreedictionary.com)
Infections13
- A 2019 Cochrane review concluded that based on very low certainty evidence in those who are critically ill "it is not clear whether bathing with chlorhexidine reduces hospital‐acquired infections, mortality, or length of stay in the ICU, or whether the use of chlorhexidine results in more skin reactions. (wikipedia.org)
- Specific Chlorhexidine -impregnated dressings from Somerville, New Jersey-based surgical technologies and solutions company Ethicon, part of the Johnson and Johnson Medical Devices Companies, have received the strongest evidence-based recommendation in the Centers for Disease Control (CDC) updated guideline on use of chlorhexidine impregnated dressings for prevention of intravascular catheter-related infections, the company said. (thefreedictionary.com)
- 1 million doses of Chlorhexidine from World Health Organization (WHO) to use for treatment of infections of umbilical cord and reduce neonatal mortality, official sources said. (thefreedictionary.com)
- The time from admission to the onset of S. aureus infections was significantly shorter in the placebo group than in the mupirocin/chlorhexidine group, at P =0.005. (medpagetoday.com)
- Chlorhexidine may not prevent infections in oral procedures but is recommendable due to its low cost and absence of adverse reactions and complications, a research team at the University of The Basque Country finds. (medindia.net)
- The drug chlorhexidine may not be an effective protection from infections that can occur from oral procedures. (medindia.net)
- Chlorhexidine is a low-cost, highly-effective antiseptic that is used for umbilical cord care to protect newborns from life-threatening infections. (psi.org)
- The purpose of this study was to determine if the use of daily chlorhexidine bathing would decrease the incidence of MRSA and VRE colonization and healthcare associated Bloodstream Infections (BSI) among Intensive Care Unit (ICU) patients. (clinicaltrials.gov)
- New CDC guidelines on the prevention of catheter related bloodstream infections recommend that the preferential use of chlorhexidine containing skin disinfectants be used for site preparation prior to insertion. (clinicaltrials.gov)
- The study found that Iodophor-based skin preparation solutions, such as 3M DuraPrep Surgical Solution (Iodine Povacrylex [0.7% available Iodine] and Isopropyl Alcohol, 74% w/w) Patient Preoperative Skin Prep, may be superior to chlorhexidine in preventing surgical-site infections. (bio-medicine.org)
- Some indwelling catheters such as urinary catheters and central venous catheters may also be coated or impregnated with chlorhexidine to prevent catheter-related infections. (hsa.gov.sg)
- Chlorhexidine Bathing Effects on Health-Care-Associated Infections. (cambridge.org)
- Reducing the Rate of Surgical Site Infections After Breast Surgery With the Use of Larger Volumes of 4% Chlorhexidine Gluconate Solution as Preoperative Antiseptic Showering. (cambridge.org)
Acetate2
Solution11
- Chlorhexidine may come mixed in alcohol, water, or surfactant solution. (wikipedia.org)
- Mouthwashes containing chlorhexidine which stain teeth less than the classic solution have been developed, many of which contain chelated zinc. (wikipedia.org)
- Cleaning solution (such as chlorhexidine ) in a single-use small applicator. (nih.gov)
- Delivery attendants will administer 0.6% chlorhexidine solution every four hours until delivery (4 washes maximum) and one neonatal wash with the same solution. (clinicaltrials.gov)
- 1 ounce (2 tablespoons) of Chlorhexidine Solution per gallon of clean water. (lambertvetsupply.com)
- Please read this leaflet carefully before you start using Chlorhexidine 0.015% and Cetrimide 0.15% Irrigation Solution. (nps.org.au)
- This leaflet answers some common questions about Chlorhexidine and Cetrimide Irrigation Solution. (nps.org.au)
- Your doctor has weighed the risks of you using Chlorhexidine and Cetrimide Irrigation Solution against the benefits this product is expected to have for you. (nps.org.au)
- Your doctor or nurse will use Chlorhexidine and Cetrimide Irrigation Solution for cleansing and irrigating the skin or dirty wounds. (nps.org.au)
- Each mL of reddish solution contains: chlorhexidine gluconate 2% w/v in a foaming vehicle. (rxmed.com)
- Baxter Exidine 4% Scrub Solution (Chlorhexidine Gluconate Gallon : Approved for various uses such as patient preoperative prep, presurgical hand scrub, skin-wound cleanser and personnel hand wash. (egeneralmedical.com)
Umbilical cord3
- Nepal was the first country in the world to use chlorhexidine to treat the umbilical cord of newborn babies, and received a USAID Pioneers Prize for reducing the neonatal death rate. (wikipedia.org)
- Chlorhexidine is very effective for poor countries like Nepal and its use is growing in the world for treating the umbilical cord. (wikipedia.org)
- It was clear that chlorhexidine, a substance applied to newborns' umbilical cord stumps to prevent infection, could reduce infant mortality significantly. (northwestern.edu)
Avoid while using chlorhe1
- What should I avoid while using chlorhexidine topical? (wellspan.org)
Group treated with chlorhexidine2
- In the study that included 8 clinical trials with 523 patients there were 267 in the group treated with chlorhexidine, in which 145 cases of bacteraemia were recorded, and 256 in the control group, in which there were 156 cases of bacteraemia. (medindia.net)
- After starting application of chlorhexidine gluconate ointment or liquid paraffin on the comedone area, the hair pore size was gradually decreased in the group treated with chlorhexidine gluconate ointment compared with the hair pore size at baseline. (dovepress.com)
Contain Chlorhexidine gluconate2
- However, there are easier-to-pronounce brands available that offer germ protection against plaque and germs and yet does not contain Chlorhexidine gluconate. (colgate.com)
- In 1998, we issued a Public Health Notice to warn health care professionals about the risk of serious allergic reactions with medical devices such as dressings and intravenous lines that contain chlorhexidine gluconate. (fda.gov)
Contains chlorhexidine gluconate1
- Patients and consumers should stop using the product that contains chlorhexidine gluconate and seek medical attention immediately or call 911 if they experience symptoms of a serious allergic reaction. (fda.gov)
Gums1
- Chlorhexidine gluconate is also available as a prescription oral chip under the brand name Periochip, which is inserted between the gums and teeth to treat periodontal disease. (fda.gov)
0.052
- ADS 205 contains not only 0.05% Chlorhexidine but also 0.05% Sodium Fluoride. (medicalsearch.com.au)
- The lowest price for Chlorhexidine g 0.5 % is $0.05 per ml for 500 mls at PharmacyChecker-accredited online pharmacies. (pharmacychecker.com)
Antimicrobial activity1
- Pioneering, award-winning work at the Queen Elizabeth Hospital, UK has demonstrated the remarkable residual antimicrobial activity of chlorhexidine on surfaces, thereby maintaining their continuous cleanliness over time. (neha.org)
Form of chlorhexidine2
- The gluconate salt form of chlorhexidine, a biguanide compound used as an antiseptic agent with topical antibacterial activity. (cancer.gov)
- The gel form of chlorhexidine has a long shelf life, requires no refrigeration, and is extremely easy to apply with minimal training. (psi.org)
Overdose of chlorhexidine2
- An overdose of chlorhexidine topical is not expected to be dangerous. (wellspan.org)
- An overdose of chlorhexidine would occur only if the medicine were swallowed. (wellspan.org)
Application of chlorhexidine1
- The purpose of this study was to determine whether the application of chlorhexidine with or without a sealant, to the etched enamel will affect the shear bond strength and the bracket/adhesive failure modes of orthodontic brackets. (unboundmedicine.com)
Risk of Anaphylaxis1
- Health Canada concluded that although uncommon, some conditions may increase the risk of anaphylaxis, such as using chlorhexidine in the mouth, on open wounds, or immediately before or during surgery. (hsa.gov.sg)
Preoperative2
- Chlorhexidine gluconate is used as a skin cleanser for surgical scrubs, as a cleanser for skin wounds, for preoperative skin preparation, and for germicidal hand rinses. (wikipedia.org)
- Adding a preoperative chlorhexidine cloth preparation protocol for total knee arthroplasty can save up to $3.18 billion annually, according to a study in The Journal of Arthroplasty . (beckersasc.com)
Percent chlorhexidine1
- Using soaps medicated with 4 percent chlorhexidine gluconate (CHG) is more effective in preventing the spread of community-acquired methicillin-resistant staphylococcus aureus (MRSA) than non-medicated soaps, says a new study. (momsteam.com)
Gluconate mouthwashes2
- What Do Chlorhexidine Gluconate Mouthwashes Treat? (colgate.com)
- Prescription chlorhexidine gluconate mouthwashes and oral chips used for gum disease already contain a warning about the possibility of serious allergic reactions in their labels. (fda.gov)
Rinses1
- The treatment of these ailments is usually based on the local application of various mucosal antiseptics in the form of rinses (e.g., chlorhexidine, cetylpyridinium, and triclosan) [ 3 , 4 ] or systemic therapy (antibiotics and antimycotics) after the clinical status deteriorates [ 5 - 7 ]. (hindawi.com)
Oral5
- The clinical significance of chlorhexidine gluconate oral rinse's antimicrobial activities is not clear. (nih.gov)
- Chlorhexidine gluconate will not treat a viral or fungal infection such as cold sores, canker sores, or oral thrush (yeast infection). (wellspan.org)
- The objective of the CHORAL study is to evaluate the de-adoption of oral chlorhexidine and the introduction of a bundle of oral care practices on selected outcomes in critically ill mechan. (bioportfolio.com)
- Can probiotics be an alternative to chlorhexidine for oral care in the mechanically ventilated patient? (bioportfolio.com)
- This study describes the unique approach of preparing mucoadhesive oral films from carmellose with incorporating a nanotechnologically modified clay mineral intercalated with chlorhexidine. (hindawi.com)
Alcohol3
- If the study is eventually translated into national guidelines," she said, "the impact would be huge," although she added that chlorhexidine/alcohol is not suitable for all types of surgery. (medpagetoday.com)
- Pitfalls in evidence assessment: the case of chlorhexidine and alcohol in skin antisepsis. (biomedsearch.com)
- Multiple clinical trial reports and systematic reviews that had assessed the clinical efficacy of chlorhexidine/alcohol combinations for skin antisepsis had attributed efficacy solely to the chlorhexidine component. (biomedsearch.com)
Healthcare4
- What should I discuss with my healthcare provider before using chlorhexidine topical? (wellspan.org)
- Using chlorhexidine at the authors' institution generated a net savings of approximately $2.1 million per 1,000 total knee arthroplasty patients, with annual healthcare savings ranging from $0.78 billion to $3.18 billion. (beckersasc.com)
- HSA would like to inform healthcare professionals about the outcome of its review on the known risk of allergic reactions, including anaphylactic reactions, with chlorhexidine-containing products. (hsa.gov.sg)
- The agencies informed healthcare professionals about the risk of serious hypersensitivity reactions with chlorhexidine-containing products, including topical anaesthetic gel and chlorhexidine-impregnated central venous catheters. (hsa.gov.sg)
Sensitivity2
- Of the eight cases, five reported the results of a skin prick test of which four were positive for chlorhexidine sensitivity. (medsafe.govt.nz)
- I work in a NICU and we commonly see patients with Chlorhexidine sensitivity/allergies. (allnurses.com)
Mouthwashes3
- Chlorhexidine is used in disinfectants (disinfection of the skin and hands), cosmetics (additive to creams, toothpaste, deodorants, and antiperspirants), and pharmaceutical products (preservative in eye drops, active substance in wound dressings and antiseptic mouthwashes). (wikipedia.org)
- Chlorhexidine is present in a variety of topical and oromucosal antiseptic preparations in the form of creams, wipes, cleansers, mouthwashes, dental implants, contact lens solutions, lozenges, topical anaesthetic medicines or antimicrobial dressings. (hsa.gov.sg)
- Chlorhexidine based mouthwashes are considered the gold standard for plaque control and inhibition. (medicalsearch.com.au)
Antisepsis2
- Chlorhexidine has attracted increasing attention for its role in skin antisepsis in recent years. (biomedsearch.com)
- We noticed and subsequently reported a widespread misinterpretation of evidence surrounding chlorhexidine and its role in skin antisepsis. (biomedsearch.com)
20183
- Chlorhexidine (CAS 55-56-1) Market Research Report 2018 aims at providing comprehensive data on chlorhexidine market globally and regionally (Europe, Asia, North America, Latin America etc. (marketpublishers.com)
- Chlorhexidine (CAS 55-56-1) Market Research Report 2018 contents were prepared and placed on the website in January, 2018. (marketpublishers.com)
- Please note that Chlorhexidine (CAS 55-56-1) Market Research Report 2018 is a half ready publication and contents are subject to change. (marketpublishers.com)
Concentrations2
- Exposure of human cells in culture to chlorhexidine at concentrations equal to or greater than 0.004% resulted in impaired cellular function and/or cell death. (nih.gov)
- A masked randomized clinical trial of three concentrations of chlorhexidine compared with natamycin 5% was carried out in consecutive patients with established corneal ulcers shown by microscopy to contain fungal hyphae and later proven to be culture positive. (nih.gov)
Efficacy1
- The superiority of 0.2% chlorhexidine over natamycin was statistically significant (relative efficacy 2.20, p = 0.043) in patients not having had prior antifungal treatment. (nih.gov)
Morbidity and morta1
- Several studies have investigated the likelihood that an anti-bacterial agent, chlorhexidine, administered during labor and delivery to mother and infant could reduce the risk of infection and of subsequent maternal and infant morbidity and mortality. (clinicaltrials.gov)
Infection6
- In the mupirocin/chlorhexidine group, 17 of 504 patients (or 3.4%) got an S. aureus infection, compared with 32 of 413 patients (or 7.7%) in the placebo group. (medpagetoday.com)
- Our Infection Control Practitioner has approached us regarding changing the brand of chlorhexidine patch we use on all central lines. (allnurses.com)
- I'm sure you've seen all the info I cited above but I guess, if they want to take a leap of faith and see how well the lower chlorhexidine GuardIVa patches compare to infection rates prior to their use, it might be worth it in the financial gain if rates stay the same (or, maybe even improve? (allnurses.com)
- 3M™ Tegaderm™ CHG Chlorhexidine Gluconate I.V. Securement Dressing has been the subject of several clinical studies by leading researchers in infection prevention and infusion therapy. (3m.com)
- Chlorhexidine topical (for the skin) is used to clean the skin to prevent infection that may be caused by surgery, injection, or skin injury. (wellspan.org)
- Based on data derived from central venous catheter insertions, we had thought that the infection rates would be lowest in the period where chlorhexidine was the preferred agent for skin preparation. (bio-medicine.org)
Ethanol2
- The medicines below all contain the following active ingredient(s): chlorhexidine + ethanol. (healthdirect.gov.au)
- Chlorhexidine Hand Lotion (Orion) is a medicine containing the active ingredient(s) chlorhexidine + ethanol. (healthdirect.gov.au)
Procedure1
- Patients were randomly assigned to nasal decolonization with mupirocin ointment and skin decolonization with chlorhexidine or to a placebo procedure. (medpagetoday.com)
Ingredients2
- Covonia throat spray contains two active ingredients, lidocaine and chlorhexidine. (netdoctor.co.uk)
- People who are allergic to any ingredients of the spray, in particular chlorhexidine. (netdoctor.co.uk)
Antibacterial2
- Chlorhexidine is a cation which interacts with anionic components of toothpaste, such as sodium lauryl sulfate and sodium monofluorophosphate, and forms salts of low solubility and antibacterial activity. (wikipedia.org)
- Antibacterial protection of suture material by chlorhexidine-functionalized polyelectrolyte multilayer films. (ebscohost.com)
Anaphylaxis4
- Severe allergic reactions including anaphylaxis have been reported following use of chlorhexidine. (medsafe.govt.nz)
- In a recent case series on anaphylaxis attributed to chlorhexidine in lubricants used in urethral catheterisation, the variety and increasing use of chlorhexidine containing products was postulated to result in sensitisation to chlorhexidine 1 . (medsafe.govt.nz)
- 2009. Anaphylaxis to the chlorhexidine component of Instillagel: a case series. (medsafe.govt.nz)
- We identified 52 cases of anaphylaxis, a severe form of allergic reaction, with the use of chlorhexidine gluconate products applied to the skin. (fda.gov)
Allergic reactions4
- This could lead to an increase in life-threatening allergic reactions to chlorhexidine. (medsafe.govt.nz)
- HSA's review of our local adverse event (AE) database did not identify any significant local signals with respect to serious allergic reactions associated with the use of chlorhexidine-containing products at this point in time. (hsa.gov.sg)
- Although rare, US FDA shared that the number of AE reports of serious allergic reactions to these products had increased over the last five decades and recommended that the product labels for over-the-counter (OTC) chlorhexidine gluconate-containing products be updated with a warning about the possibility of serious allergic reactions. (hsa.gov.sg)
- Its safety review took into account 53 domestic reports of serious allergic reactions with the use of non-prescription topical chlorhexidine-containing products, including three anaphylactic reactions, as well as published cases in medical literature. (hsa.gov.sg)
Iodine1
- (EN) The present invention relates to a novel composition comprising chlorhexidine, iodine and at least one physiologically acceptable carrier, for use in the treatment and/or prevention of periodontal and/or implant-related diseases. (wipo.int)