ACNE-like skin eruptions caused by exposure to CHLORINE-containing compounds. Exposure can be by inhalation, ingestion, or through the skin. Chloracne is often seen in people who have occupational contact with chlorinated pesticides, wood preservatives, and sealants.
A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.
Chlorinated hydrocarbons containing heteroatoms that are present as contaminants of herbicides. Dioxins are carcinogenic, teratogenic, and mutagenic. They have been banned from use by the FDA.
A chemical by-product that results from burning or incinerating chlorinated industrial chemicals and other hydrocarbons. This compound is considered an environmental toxin, and may pose reproductive, as well as, other health risks for animals and humans.
A recurrent contact dermatitis caused by substances found in the work place.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Herbicides that remove leaves from trees and growing plants. They may be either organic or inorganic. Several of the more persistent types have been used in military operations and many are toxic. (From Hawley's Condensed Chemical Dictionary, 11th ed)
An herbicide with strong irritant properties. Use of this compound on rice fields, orchards, sugarcane, rangeland, and other noncrop sites was terminated by the EPA in 1985. (From Merck Index, 11th ed)
An herbicide with irritant effects on the eye and the gastrointestinal system.
A conflict occurring from 1954 through 1975 within the Republic of Vietnam. It involved neighboring nations and the United States and other members of the Southeast Asia Treaty Organization.
An agency in the Executive Branch of the Federal Government. It was created as an independent regulatory agency responsible for the implementation of federal laws designed to protect the environment. Its mission is to protect human health and the ENVIRONMENT.
The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.
Substances or energies, for example heat or light, which when introduced into the air, water, or land threaten life or health of individuals or ECOSYSTEMS.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment.
Disorders claimed as a result of military service.
An autosomal dominant or acquired porphyria due to a deficiency of UROPORPHYRINOGEN DECARBOXYLASE in the LIVER. It is characterized by photosensitivity and cutaneous lesions with little or no neurologic symptoms. Type I is the acquired form and is strongly associated with liver diseases and hepatic toxicities caused by alcohol or estrogenic steroids. Type II is the familial form.
A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
Former members of the armed services.
An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA.
Phylum of green nonsulfur bacteria including the family Chloroflexaceae, among others.
Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.
Compounds that contain a BENZENE ring fused to a furan ring.
A greenish-yellow, diatomic gas that is a member of the halogen family of elements. It has the atomic symbol Cl, atomic number 17, and atomic weight 70.906. It is a powerful irritant that can cause fatal pulmonary edema. Chlorine is used in manufacturing, as a reagent in synthetic chemistry, for water purification, and in the production of chlorinated lime, which is used in fabric bleaching.

Repression of aryl hydrocarbon receptor transcriptional activity by epidermal growth factor. (1/4)

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Inflammatory and chloracne-like skin lesions in B6C3F1 mice exposed to 3,3',4,4'-tetrachloroazobenzene for 2 years. (2/4)

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Proceedings of the 2010 National Toxicology Program Satellite Symposium. (3/4)

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Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down. (4/4)

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Chloracne normally results from direct skin contact with chloracnegens, although ingestion and inhalation are also possible causative routes. Chloracnegens are fat-soluble, meaning they persist in the body fat for a very long period following exposure. Chloracne is a chronic inflammatory condition that results from this persistence, in combination with the toxins chemical properties. It is believed, at least from rodent models, that the toxin activates a series of receptors promoting macrophage proliferation, inducing neutrophilia and leading to a generalised inflammatory response in the skin. This process may also be augmented by induction of excess tumor necrosis factor in the blood serum. The inflammatory processes lead to the formation of keratinous plugs in skin pores, forming yellowish cysts and dark pustules. The associated pus is usually a color of green approximating that of a tennis ball. The skin lesions occur mainly in the face, but in more severe cases they involve the shoulders ...
The three-dimensional culturing of human keratinocytes at the air-liquid interface yields a fully stratified epidermis including a functional stratum corneum and thus enables the study on epidermal structure and function in the context of biomedical, toxicological and pharmaceutical sciences. Here we provide a step-by-step detailed protocol for the isolation of human primary keratinocytes and the development of human epidermal equivalents generated from primary keratinocytes or immortalized keratinocytes (N/TERT-1; N/TERT-2G), including widely accepted procedures for the analysis of barrier function, tissue morphology, cell proliferation, and gene expression ...
Proceedings of Beijing Satellite Symposium of The Eighth International Congress of Biorheology, The Beijing Satellite Symposium of the Eighth International Congress of Biorheology will be held in Beijing, China, on August 11-13, 1992. Biorheology comprises the study of deformation and flow of,All books from China,especially scientific and academic books,export Chinese and English version books to libraries and book stores over the world,China Scientific Book Services:The Best Professional China Books,hceis.com
OBJECTIVE--The aim was to examine the long term morbidity experience of men exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). METHODS--A retrospective cohort morbidity study of 158 men first exposed to TCDD between 17 November 1953 and 16 November 1954 subdivided by chloracne state and back calculated TCDD blood lipid concentration, and 161 referents. Cause specific illness absence and admissions to hospital were examined between 1953 and 1989. RESULTS--On an ever or never basis, thyroid disease and appendicitis were diagnosed more often in the study group; these diseases were not differentially distributed by chloracne state, but were increased in the high TCDD subgroup. An 18% increase in total illness episodes was also seen (p = 0.002); illness rates increased with severity of chloracne and higher TCDD concentration within the chloracne subgroup. There were increases in infectious and parasitic diseases (primarily ill defined intestinal infections), disorders of the peripheral nervous ...
The following satellite symposia were held in association with the 2017 MAD-ID Annual Meeting. Satellites scheduled for the 2018 meeting will be posted here at a later date. ...
A satellite symposium to be held on March 30, 2014 at the 40th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) in Milan
Purpose of this symposium is to inform renal physicians and dialysis directors about recognition and management of HCV in patients with renal disease, including issues associated with dialysis and transplantation.. Friday, March 16, 2018 ...
7:00 p.m. - 10:00 p.m. Pacific Time This activity, the fourth of a 4-part live webinar series, will feature 5 lymphoma investigators serving as faculty. Research To Practice (RTP) president Dr Neil Love will moderate the program. Prior to live webinar, the faculty plus 3 other investigators will complete a pre-survey to ascertain their perspectives on controversial questions/scenarios related to the management of Hodgkin and NHL, including FL, mantle cell and DLBCL. Responses from all 8 investigators will be depicted as Treatment Preference Matrices (TPMs). Additionally, RTP will conduct a Patterns of Care (POC) survey of 75 US general oncologists featuring many of the same questions posed to the experts. Findings from the surveys will serve as the foundation for the FSS virtual program on Dec 4th. The live webcast will be divided into 5 modules, with each featuring 2 segments - (1) discussion of a series of TPMs and (2) corresponding POC survey results and a faculty member-led review of ...
Juan Cosin Chair by Cristina Avendaño (Madrid, Spain) Chair (Dr. Cristina Avendaño): Brief introduction (10 - 15 min.) with background information on the rationale of a fixed dose co​mbination (polypill) for cardiovascular prevention. General overview of the regulatory requirements as compared with the clinical need of a polypill in CVD prevention (efficacy, experience of use, and Clinical Practice Guidelines recommendations based on the single components) and how this can be reflected in the SmPC.​. Expert (Dr. Juan Cosin): Under his presentation Why do I need a polypill like this to treat my patients?, the expert will review (20 min.) the available clinical data for Trinomia® (Ferrers approved aspirin, atorvastatin and ramipril fixed dose combination) and then he will share different clinical case studies of real life patients that are candidates to treated with a cardiovascular polypill (60 min. approx.). The expert will challenge the audience with questions related to the ...
The 2011 American Heart Association and the 2011 EAS/ESC Guidelines for Prevention of Cardiovascular Disease in Women: the gynecologists point of ...
Oncoletter wird über nicht öffentlich zugängliche Werbung für Medizinalpersonen finanziert. Oncoletter finanziert sich zudem mit von Kongressorganisatoren beauftragten Aufnahmen ganzer Kongresse oder Symposien. Weitere Finanzierungsquellen werden bei den jeweiligen Berichten aufgeführt. Die Inhalte der Website von Oncoletter sind strikt redaktionell und widerspiegeln die Meinungen und Ansichten der Autoren. ...
ACCREDITATION STATEMENT. The Endocrine Society is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.. The Endocrine Society has achieved Accreditation with Commendation.. The Endocrine Society designates this live activity for a maximum of 4.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.. LEARNING OBJECTIVES. Upon completion of this educational activity, learners will be able to:. ...
The management of differentiated thyroid cancer is becoming increasingly complex as clinicians and patients strive to develop individualized management plans designed to achieve excellent outcomes without subjecting the patients to excessive therapy or testing. The dramatic increase in the incidence of low risk papillary thyroid cancers has caused us to re-evaluate our traditional therapeutic approaches such that many low risk patients may be more than adequately treated with thyroid lobectomy (and even without immediate surgical intervention in selected patients). On the opposite end of the spectrum, advances in our understanding of the molecular biology of thyroid cancer and the success of several systemic therapy trials has opened up new avenues of therapy for high risk patients with advanced disease. Through a combination of lectures, panel discussions, and case-based presentations, we will examine the most important, and often controversial, management issues faced by clinicians across the ...
Kiadis Pharma is a clinical stage biopharmaceutical company focused on research, development and future commercialization of cell-based immunotherapy products for the treatment of blood cancers and inherited blood disorders. The Company believes that its innovative products have the potential to address the current risks and limitations connected with allogeneic hematopoietic stem cell transplantation (HSCT), being graft-versus-host disease (GVHD), cancer relapse, opportunistic infections and limited matched donor availability. HSCT is generally regarded as the most effective curative approach to blood cancers and certain inherited blood disorders and the Company expects that HSCT could become a first-choice treatment for blood cancers and inherited blood disorders once current risks and limitations are addressed, thereby meeting a significant unmet medical need with its products.. The Companys product ATIR101™ is being tested using a single-dose regimen in an open-label fully enrolled Phase ...
It is well established that inflammation promotes cancer, including melanoma, although the exact mechanisms involved are less known. In this study, we tested the hypothesis that inflammatory factors affect the cancer stem cell (CSC) compartment responsible for tumor development and relapse. Using an inducible histone 2B-GFP fusion protein as a tracer of cell divisional history, we determined that tumor necrosis factor (TNF), which is a classical pro-inflammatory cytokine, enlarged the CSC pool of GFP-positive label-retaining cells (LRCs) in tumor-like melanospheres. Although these cells acquired melanoma stem cell markers, including ABCB5 and CD271, and self-renewal ability, they lost their capacity to differentiate, as evidenced by the diminished MelanA expression in melanosphere cells and the loss of pigmentation in a skin equivalent model of human melanoma. The undifferentiated cell phenotype could be reversed by LY294002, which is an inhibitor of the PI3K/AKT signaling pathway, and this reversal was
At the IPVS, animal health company Boehringer Ingelheim organized its symposium: 'Translating science into performance'. The well attended satellite symposium discussed the principles of vaccination, the use of mixed vaccines among others.
click on the image above to watch the webcast (to view the webcast in fullscreen, click on the bottom right square icon underneath the YouTube logo) This video is the fifth in a five-part series that focuses on new strategies for multiple myeloma care. It was presented during the Friday Satellite Symposium preceding the 61st ASH Annual Meeting & Exposition in Orlando, FL
Members can review presentation slides in the Members-Only section. Sunday, 24 June. 13:00 - 20:00 Registration Open. 15:30 - 16:15 Plenary Session 1. Chairman: C. Kauffmann (USA. Immune Reconstitution after HSCT H. Einsele (GER). Merck Sharp & Dohme Satellite Symposium. 16:30 - 18:30 Important Considerations for Limiting the Impact of Invasive Fungal. Infections in Immuncompromised Patients. Chairmen: C. Viscoli (ITA) & D. Kontoyiannis (USA). 16:30 - 16:40 Welcome & Opening Remarks. C. Viscoli (ITA). 16:40 - 17:05 Unmet Medical Needs for the Management of Invasive Fungal Infections. D. Kontoyiannis (USA). 17:05 - 17:30 Current Treatment strategies for Management of Invasive Aspergillosis. C. Viscoli (ITA). 17:30 - 17:55 Current Strategies for Management of Candidemia and Invasive Candidiasis. M. Bassetti (ITA). 17:55 - 18:20 Panel Discussion. Factuly. 18:20 - 18:30 Closing Remarks. D. Kontoyiannis (USA). 19:00 - 20:00 Welcome Reception. Monday, 25 June. 08:00 - 09:00 Meet-the-Expert ...
35 Simposio Europeo de la ECTS. Barcelona 24-28 de mayo de 2008. Dear Colleagues,. It is with great pleasure that we invite you to participate in the 35th European Symposium on Calcified Tissues, to be held in the exciting city of Barcelona, Spain, from 24-28 May 2008. The 2008 meeting will offer a high quality scientific programme of interest to both clinical and basic scientists. We are expecting around 3000 delegates to attend. Highlights will include the following:. * An exciting programme of invited speaker lectures featuring some of the worlds leading experts in the field. * Meet the professor sessions. * Dedicated allied health professionals session. * New - Joint ECTS-ASBMR debate. * A high proportion of submitted abstracts selected for the oral programme (over 15% in 2007). * Well-attended poster sessions with dedicated poster viewing time. * A busy exhibition area with lunch included in the delegate fee. * Company-supported satellite symposia highlighting some of the latest ...
Vevey, Switzerland, November 2010 - Research into the nutrient needs of the older adult and the impact that malnutrition has on patient health status was shared at the Nestlé Nutrition Institute Satellite Symposium at the 32nd ESPEN Congress in Nice in September 2010. Prof. Sieber, Chief of Geriatrics at the Klinikum Nürnberg (Germany) and chairman of this symposium, addressed the need to focus on functionality rather than chronological or biological age.. Changing nutritional needs of the elderly Professor Dorothee Volkert, from the Institute for Biomedicine of Aging at the University of Erlangen-Nürnberg (Germany), showed that nutrient needs vary with health, functional and nutritional status, physical activity and lifestyle. As people age, there is a reduction in lean body mass and the metabolic rate decreases as does physical activity, contributing to an overall reduction in energy needs. The German National Food Consumption Study showed that there is a reduction of energy intake of ...
10/31/2016 07:00:00 10/31/2016 08:00:00 Chemical Neuromodulation as a Novel Approach to Renal Denervation TCT 2017 true MM/DD/YYYY TCT 2014 Satellite Symposia - Breakfast Program Apple CalendarGoogle (online)OutlookOutlook.com (online)Yahoo (online)AddEvent.com ...
Cytomegalovirus: Down but Not Out. by John R. Wingard, MD, Editor. Once the most feared infectious pathogen threatening patients after hematopoietic cell transplantation, cytomegalovirus (CMV) today is merely a shadow of its former self. Introduction of effective antivirals, validation of bronchoalveolar lavage as a less invasive means of diagnosis of CMV pneumonia, development of rapid diagnostic methods for analyzing blood specimens to identify infection before onset of disease, and testing of prophylactic and preemptive strategies to prevent morbidity and mortality have all contributed to tame this bully. The battle is not ended, however. This organism continues to stage ambushes that necessitate continued vigilance.. In this transcript of a satellite symposium held at the annual Tandem BMT Meetings in Keystone, Colorado, January 30 to February 4, 2003, current management strategies and continuing clinical dilemmas are discussed. The first presentation reviews the progress made in prevention ...
http://www.ebpom.org/. EPOM has a fantastic programme again this year. We are pleased to announce that our annal meeting will be appearing as a satellite symposium check the link above for further information and booking.. ...
The Conference will provide a forum for the presentation and discussion of recent research and development activities in fundamental and applied crystallogenesis and mineralogy. The scientific program will include both oral and poster sessions, as well as plenary and invited talks to provide a complete picture of the latest developments in the field. A satellite symposium Deep carbon cycle: mineralogy and crystal chemistry of carbon-bearing compounds and a post-conference Workshop Frontiers of crystallography are also planned ...
You need to REGISTER WITH HDCN (its free) before you can access these talks. This program offers 1.5 hours of Category One CME Credit for Physicians and 1.75 contact hours for nurses through Medical Education Resources. ...
On behalf of the ESH 2019 Scientific and Organizing Committees, we would like to extend our thanks to all those who contributed to the success of ESH 2019. Your support and participation helped to make it another incredible congress edition.. Close to 2500 attendees gathered from around the globe for a wonderful opportunity to connect with new and old peers at ESH 2019.. Exciting scientific sessions, satellite symposia and exhibition kicked off after the welcome from the ESH President at the Opening Ceremony.. We would like to thank all abstract submitters for their contribution. Over 1000 abstracts were received.. The Poster sessions had a high attendance as delegates showed great interest. We are proud to have hosted another outstanding programme.. The ESH and the Organizing Committee is looking forward to welcoming you to the Joint ESH/ISH Meeting in Glasgow from May 29 - June 1, 2020.. ...
Cardiology Events, cardiovascular and electrophysiology, programme information, keynote speakers, exhibitors, important satellite symposia and helpful infos.
What is missing from your biomarker analysis? Meet our scientists at our booth and at our free Satellite Symposium, to learn how researchers use RNAscope® technology to enhance their research. Join us in San Diego for Neuroscience 2016! REGISTER
Wiegersma, S., Sools, A.M., Van Noije, A.J., & Veldkamp, B.J. (2016). DIY Text Classification: The development of a supervised text classification tool. Presentation at the 7th RCEC Workshop on IRT and Educational Measurement. Organized by RCEC, University of Twente, Enschede.. Wiegersma, S., Sools, A.M., & Veldkamp, B.P. (2016). Exploring Letters from the Future by visualizing narrative structure. Presentation at the Computational Models of Narrative conference (CMN), Satellite symposium of The Digital Humanities conference, Krakow.. Wiegersma, S., Sools, A.M., Veldkamp, B.P., & Westerhof, G.J. (2016). What works when for whom? Advancing therapy change process research by mining for therapy-related textual features in effective e-mental health interventions. Presentation at the Conference Supporting Health by Technology VII, Groningen. Organized by the Center for eHealth & Wellbeing Research (UT) and the University Medical Center Groningen.. Wiegersma, S. IGS Datalab. Research Data Support. ...
2011. Mouraux A. Structural Plasticity & Reorganization in Chronic Pain. Satellite symposium of the 7th Congress of the European Federation of IASP Chapters (EFIC) - Pain in Europe VII. Heidelberg. Sept. 2011. ...
Auto Merging Procedure of Electronic Circuit with 3D PEEC Equivalent Model of PCB Layout. New PCB import options give possibility to extract BOM report (Bill of Material) from ODB++ file format. During importing information about all PCB components and pins is translated from ODB++ to Excel spreadsheet - an essential part of automatic merging procedure.. As a result of 3D PEEC calculation equivalent circuit of PCB layout will be automatically merged with functional scheme based on BOM data. Netlist device representing initial functional circuit can be easily substituted with complete scheme including all parasitic effects of PCB traces directly in System Diagram, preserving all the existing connections to other devices.. ...
On Tuesday, with the release of pricing and pre-orders for the new Surface RT tablets, Twitter exploded with comparisons to the iPad. So, I decided to put together a little comparison chart to contrast two equivalent models.
Title: Busemann limits for a corner growth model with deterministic inhomogeneity Abstract: Busemann limits have become a useful tool in study of geodesics in percolation models. The properties of these limits are closely related to the curvature of the limit shapes in the associated growth models. In this talk, we will consider a corner growth model (CGM) with independent exponential weights. The rates of the exponentials are deterministic and inhomogeneous across columns and rows. (An equivalent model is the TASEP with step initial condition and with particlewise and holewise deterministic disorder). In particular, the model lacks stationarity. Under mild assumptions on the rates, the limit shape in our CGM exists, is concave and can develop flat regions only near the axes. In contrast, flat regions can only occur away from the axes in the CGM with general i.i.d. weights. This feature and stationarity have been instrumental in proving the existence of the Busemann limits in past work. We will ...
Title: Busemann limits for a corner growth model with deterministic inhomogeneity Abstract: Busemann limits have become a useful tool in study of geodesics in percolation models. The properties of these limits are closely related to the curvature of the limit shapes in the associated growth models. In this talk, we will consider a corner growth model (CGM) with independent exponential weights. The rates of the exponentials are deterministic and inhomogeneous across columns and rows. (An equivalent model is the TASEP with step initial condition and with particlewise and holewise deterministic disorder). In particular, the model lacks stationarity. Under mild assumptions on the rates, the limit shape in our CGM exists, is concave and can develop flat regions only near the axes. In contrast, flat regions can only occur away from the axes in the CGM with general i.i.d. weights. This feature and stationarity have been instrumental in proving the existence of the Busemann limits in past work. We will ...
Pressure ulcer risk assessment might be optimized by incorporating the soft tissue reaction to mechanical loading in the currently used risk assessment scales. Cytokines, like IL-1alpha, IL-1RA, IL-8, and TNF-alpha, might be used to determine this tissue reaction, since they are released after 24 h …
Although the appreciation of the unique taste properties of glutamate as the compound responsible for umami has spread in the last years among chefs and food lovers, the role of glutamate as a flavoring agent in foods and its metabolic...
Real-world data from over 40,000 patients will be presented at a satellite symposium, and at one platform and three poster presentations.. The satellite symposium, titled Anticoagulation and atrial fibrillation (AF): real life data from the GARFIELD-AF Registry will feature an expert faculty discussing the design of GARFIELD-AF in the context of the value that registries bring to clinical research. They will also present the latest data on treatment and outcomes in the global population and in specific patient subgroups. The Oral session, Vitamin K antagonist control in Eastern and Southeastern Asia will include a comparison of the distribution of international normalised ratio values in patients receiving a vitamin K antagonist for newly diagnosed atrial fibrillation in countries in Eastern and Southeastern Asia with that for patients in other countries represented in GARFIELD-AF.. The three poster presentations will look at patterns of uptake of non-vitamin K antagonist oral anticoagulants ...
We evaluated the response to salt restriction in hypertensive patients receiving drugs. By restricting their salt intake to less than 80 mmol of sodium per day for 3 months, 50% of patients reaching goal compliance were able to discontinue diuretics. The literature also reveals responses to a low salt diet. Salt restriction augmented the hypotensive effect of chlorthalidone in two investigations, but not in another, and the hypotensive effect of beta-blockers in three trials. Sodium intake of 10 mmol/day caused a much greater decrease in blood pressure in response to a single dose of captopril than did a sodium diet of 200 mmol/day. In patients receiving various fixed regimens for 2 months, salt restriction decreased blood pressure in all but those receiving calcium blockers. A single dose of nifedipine lowered blood pressure more in patients receiving 350 mmol of sodium per day than in the same patients given 150 or 10 mmol/day. Verapamil for 3 days was more effective in patients receiving 212 ...
Twenty-Fourth Annual Missouri Plant Biology Symposium Plant Protein Phosphorylation-Dephosphorylation May 22-24, 2007 and Mini-Symposium on Plant Proteomics May 24-25, 2007 The Missouri Plant Biology Symposium, organized by the University of Missouri Interdisciplinary Plant Group, will be on plant protein phopshorylation-dephoshorylation . The venue for the symposium is MUs Christopher S. Bond Life Sciences Center. The symposium begins on Tuesday the 22nd and ends on the 24th with the speaker/student/postdoc dinner. There will be a satellite symposium that will overlap with this years symposium on Plant Proteomics. This satellite meeting will include a joint session on phosphoproteomics on the afternoon of the 24th. For more information including the list of invited speakers, instructions for registration and abstract submission can be found on the Missouri Plant Biology Symposium web page. http://www.plantgroup.org/symposium.php Please bookmark the Symposium Web page to keep up to date with ...
THOUSAND OAKS, Calif., and COLLEGEVILLE, Pa., June 16, 2003 - Amgen (NASDAQ: AMGN) and Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), today announced the positive results of a new study. The study assessed the efficacy, including impact on joint damage and disease activity, in rheumatoid arthritis (RA) patients following year-long treatment with a combination of ENBREL. (etanercept) plus methotrexate, compared with either treatment alone. Results of the study will be presented this week at a satellite symposium during the European League Against Rheumatism meeting in Lisbon, Portugal. ...
CML Headlines Working Towards a Cure in CML - Breakfast Satellite Symposium - CBMTG - April 2012, Toronto, Ontario - preview of Canadian CML Guidelines
The landscape of renal cell carcinoma (RCC) management has changed dramatically in recent years with the approval of new agents. The availability of these agents, along with data updates on their efficacy and safety, has complicated RCC treatment planning in terms of therapeutic selection and sequencing, toxicity management, and dose/schedule optimization. Additionally, positive results from studies of novel single-agent and combination therapies, biomarkers, and approved agents in new lines of therapy suggest more changes are on the horizon in RCC management. To help clinicians in their day-to-day practices, this case-based satellite symposium will broach a variety of clinical scenarios at key junctures in care, with the understanding that real-world scenarios cannot always be bucketed neatly into simple lines of therapy. The format of this activity will provide the audience with an opportunity to interact with the expert faculty panel and to reflect on how they arrive at the decisions they ...
Nutricia Satellite Symposia give healthcare professionals access to the latest scientific developments in the field of medical nutrition.
Nutricia Satellite Symposia give healthcare professionals access to the latest scientific developments in the field of medical nutrition.
We are super stoked to announce that the OYM team will be at the Canadian Neuroscience meeting in Toronto this year, hosting an exciting new satellite symposium on science communication! Come talk about the importance of communication in neuroscience with special guest speakers!. Other than shamelessly self-promoting, the hosts have got a whole lot on their minds this week. Theyre both on writing duty this week and have been thinking about the way that their science is portrayed and how it fits into the big picture. Kats been reading up a lot (like, a lot a lot) on the misuse of statistics in the wake of the American Statistical Associations statement on p values. Plus, shes back on a podcast kick and is a new fan of the Bold Signals Podcast. Meanwhile, Liams been spending some free time on Twitter and catches us up on the hashtag #BiologySpaceFacts before we move onto this weeks paper.. The media attention drew our attention to this study that was published as a letter in Nature. In it, ...
Pani, S, Arfelli, F, Bravin, A, Cantatore, G, Longo, R, Olivo, A, Poropat, P, Rigon, L, Tromba, G, Castelli, E et al, Fantini, A, Tartari, A, Gambaccini, M, Pani, R, Bollini, D and Del Guerra, A. (2000) Tomographic imaging with synchrotron radiation In: Satellite Symposium of the European-Congress-of-Radiology, 2000-03-05 - 2000-03-10, VIENNA, AUSTRIA. Full text not available from this repository ...
Information on chloracne, a skin condition VA recognizes in Veterans as associated with Agent Orange exposure during military service.
2,3,7,8 Tetrachlorodibenzo-p-dioxin (TCDD), a ubiquitous environmental toxin, has been shown to cause a human skin pathology called chloracne. The majority of laboratory mouse strains, with the exception of mice bearing a mutation in thehairless gene, fail to display overt signs of chloracne upon exposure to TCDD. As a result, only minimal data exist on the effects of TCDD in adult haired mice and no data exist on the effects of TCDD in developing mouse skin. Here we report that TCDD affects the temporal expression of protein markers of keratinocyte terminal differentiation during murine skin morphogenesis. Immunohistochemical analysis of E16 mice reveals accelerated expression of the intermediate filament-associated protein filaggrin in response to TCDD. At a later developmental time and after birth, expression of filaggrin and loricrin is indistinguishable between treatment and control groups. At E16 expression of keratins 5, 6, and 10 are unaltered in TCDD-exposed individuals and TUNEL ...
At the present time, the only persistent effect associated with dioxin exposure in humans is chloracne. Other health effects that have been reported include peripheral neuropathies, fatigue, depression, personality changes, hepatitis, enlarged liver, abnormal enzyme levels and porphyria cutanea tarda though no causal relationships were established in every case. Results of a study on 1,520 workers known to have been exposed to 2,3,7,8-TCDD for a period of at least one year, and with a latency of at least twenty years between exposure and diagnosis of disease, revealed a slightly, but significantly elevated mortality from soft tissue sarcoma and cancers of the respiratory system. As with other studies, interpretation of results was limited by the small number of deaths and by possible confounders including smoking and other occupational exposures. Two recent studies followed a young population from the area of the Seveso, Italy industrial accident. The first, a cancer study, examined a cohort of ...
If you have recently received a favorable decision from the VA on your Agent Orange claim, you may think that the long fight with the VA is over. But before you decide not to appeal the decision, you will want to be sure that the VA got both the disability rating and the effective date correct. Perhaps the most complicated issue when it comes to Agent Orange-related claims are the special effective date rules (found in 38 C.F.R. 3.816) that apply to some veterans as a result of the Nehmer class action lawsuit. Note that the special Nehmer effective dates apply only to veterans who served on the landmass of Vietnam or its inland waterways (hopefully soon to include Da Nang Harbor).. Before we discuss the Nehmer effective date rules, it is helpful to understand the basics of the Nehmer class action itself. The lawsuit was filed in 1986 (and certified as a class action in 1987) to challenge a VA regulation from 1985 which gave presumptive status to chloracne claims only. In 1989, the court ...
Satellite Symposia Series with leading experts in skin & hair science Friday June 12 Hair Dye Allergies Reducing the Risk Through Innovation 2-Methoxymetyl-p-phenylenediamine (ME-PPD) - an alternative to pPD and pTD with significantly reduced allergy induction risk and promising but not risk-free cross-elicitation potential 17.00 to 19.00 - Vancouver Convention Centre - West 114-115 Sponsored by Chair: Dr. John Gray MD, Durban, South Africa Faculty/Speakers: Professor Anthony Gaspari MD, University of Maryland School of Medicine, Baltimore, Maryland, USA Dr. Amir Zahir MD, University of Maryland School of Medicine, Baltimore, Maryland, USA Dr. Carsten Goebel PhD, Procter and Gamble, Schwalbach, Germany Dr. Harald Schlatter PhD, Procter and Gamble, Schwalbach, Germany Summary p-Phenylenediame (PPD) and p-toluylenediamine (PTD) are the most common ingredients in oxidative hair colorant products and guarantee outstanding colour results. However, they are known to be drivers of hair dye allergies ...
Activity Instructions. This activity is eligible for credit through November 15, 2013. After this date, this activity will expire and no further credit will be awarded.. Expected time to complete this activity as designed: 60 minutes. The content of this supplement, Highlights of an ESH-iCMLf Satellite Symposium - Monitoring, Treatment Resistance, and Treatment Failure in Chronic Myeloid Leukemia: Breaking Barriers to Improved Outcomes and Looking Forward to a Cure, is a component of an online CME activity and CNE activity.. CE Accreditation. CME Credit Accreditation Statement: The Medical College of Wisconsin is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.. Designation of Credit: The Medical College of Wisconsin designates this enduring material a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.. Nursing ...
P. Ostaszewski, Jean Grizard, Isabelle Papet, S. Nissen. Comparison of the effects of 2-ketoisocaproate and 3-hydroxy-3-methylbutyrate on growth, insulin and IGF1 kinetics in lambs. Satellite symposium to VIII ISRP, Sep 1994, Warsaw, Poland. 1994, The developing of digestive and metabolic processes in new born and growing ruminants. ⟨hal-02774239⟩ ...
In many industrial domains, numerical simulation has been adopted as a primary tool for optimizing processes and devices. However, the simulation of high-intensity focused ultrasound (HIFU) treatments presents specific challenges. Thus, modeling the lesion creation process remains complex in many clinically relevant situations, where cavitation or boiling occur [1]. In these cases, where the influence of the bubble cloud cannot be directly simulated, equivalent models have to be developed [1, 2]. Beyond their predictive capability, which is by nature restricted, they aim at producing a useful understanding [1] by identifying the main physical phenomena shaping the lesion. In this context, this paper describes a rigorous approach for designing, calibrating, and validating an equivalent model to simulate the in situ temperature field.. Acoustic simulation of HIFU beams has been greatly studied during the past decades, and several wave equations have been derived, such as the widely used ...
Self-learning equivalent-convolutional neural structures (SLECNS) for auto-coding-decoding and image clustering are discussed. The SLECNS architectures and their spatially invariant equivalent models (SI EMs) using the corresponding matrix-matrix procedures with basic operations of continuous logic and non-linear processing are proposed. These SI EMs have several advantages, such as the ability to recognize image fragments with better efficiency and strong cross correlation. The proposed clustering method of fragments with regard to their structural features is suitable not only for binary, but also color images and combines self-learning and the formation of weight clustered matrix-patterns. Its model is constructed and designed on the basis of recursively processing algorithms and to k-average method. The experimental results confirmed that larger images and 2D binary fragments with a large numbers of elements may be clustered. For the first time the possibility of generalization of these ...
We Buy Oven Lamps,Cooker Lamp 31 Mar, 2018. Dear Sir, We are from the Supreme Ind Limited INDIA, we are using the High temperature oven Light as per attached Photo, These lights do not having facility to replace the Lamo, Pl. send the offer for the best quality light with equivalent model where we can replace the Lamp when it get fuse. Pl. send the offer for the same, Regards, Piyush yadav The ...
Many workers had chloracne. In a NIOSH study in the U.S., the average concentration of TCDD in exposed persons was 233 ng/kg ( ... TCDD concentration in fat was 108,000 pg/g. Also in this case the most prominent symptom was chloracne after initial stomach ... By far the best proven effect is chloracne. The suspected effects in adults are liver damage, and alterations in heme ... The main feature was chloracne, a serious skin disease. The victim survived, and other symptoms were modest after initial ...
In a study conducted by the CDC and the Missouri Division of Health, no cases of chloracne, a common symptom of acute dioxin ... Twelve horses died, and children exposed to the arena were diagnosed with chloracne, a skin condition associated with dioxin ... Suskind, Raymond (1984). "Chloracne, "the hallmark of dioxin intoxication"". Scandinavian Journal of Work, Environment & Health ...
He suffered from chloracne for many years, but after initial malaise, other symptoms or abnormal laboratory findings were few. ... The acute effects were limited to about 200 cases of chloracne. Long-term effects seem to include a slight excess of multiple ... They survived but suffered from difficult chloracne for several years. The poisoning likely happened in October 1997 but was ...
A reporter was diagnosed with chloracne, a condition associated with over-exposure to dioxins, following sustained exposure to ... "Hong Kong reporter diagnosed with chloracne after tear gas exposure, prompting public health concerns". Hong Kong Free Press. ...
She suffered from chloracne, nausea, vomiting, epigastric pain, loss of appetite, leukocytosis, anemia, amenorrhoea and ... known as chloracne. High occupational or accidental levels of exposures to dioxins have been shown by epidemiological studies ... and was diagnosed only after a toxicologist recognized the symptoms of chloracne while viewing television news coverage of his ... who apparently suffered no notable negative effects other than chloracne. These patients were provided with olestra to ...
Dioxins have been associated with several adverse effects in humans, including immune and enzyme disorders, chloracne, and are ...
... because workers at its chemical plants were developing chloracne. In the study, Kligman applied about the same amount of dioxin ...
The best proven is chloracne.[2] Even in poisonings with huge doses of TCDD, the only persistent effects after the initial ... Many workers had chloracne. In a NIOSH study in the U.S., the average concentration of TCDD in exposed persons was 233 ng/kg ( ... malaise have been chloracne and amenorrhea.[17][18] In occupational settings many symptoms have been seen, but exposures have ...
Six workers that cleaned up afterwards got seriously intoxicated and developed chloracne. After twelve years, four of the six ...
... chloracne); liver, stomach, and thyroid gland injuries (including hepatocarcinoma),[citation needed], and thymocyte apoptosis.[ ... such as chloracne and rashes, but these were known to be symptoms of acute systemic poisoning dating back to 1922. Studies in ...
A study published in 1998 concluded that chloracne (nearly 200 cases with a definite exposure dependence) was the only effect ... The most evident adverse health effect ascertained was chloracne (193 cases). Other early effects noted were peripheral ... 1,600 people of all ages had been examined and 447 were found to suffer from skin lesions or chloracne. An advice center was ...
79 employees contracted chloracne whilst cleaning up and even some of their families were affected by traces brought home on ...
... killing 3,000 pets and farm animals and causing 193 cases of chloracne (which is, according to a prominent toxicologist, what ...
... "chloracne"). It was only in the mid-1950s that chloracne was associated with aromatic hydrocarbons.[2] The substances that may ... 193 cases of chloracne occurred in Seveso, Italy in 1976 following an industrial accident in which up to a few kilograms of ... Chloracne is an acne-like eruption of blackheads, cysts, and pustules associated with over-exposure to certain halogenated ... However, chloracne itself can be highly resistant to any treatment. The course of the disease is highly variable. In some cases ...
Chloracne, due to exposure to certain chemicals, may look very similar to acne vulgaris.[74] ...
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system-the organ system that encloses the body and includes skin, hair, nails, and related muscle and glands.[1] The major function of this system is as a barrier against the external environment.[2] Conditions of the human integumentary system constitute a broad spectrum of diseases, also known as dermatoses, as well as many nonpathologic states (like, in certain circumstances, melanonychia and racquet nails).[3][4] While only a small number of skin diseases account for most visits to the physician, thousands of skin conditions have been described.[5] Classification of these conditions often presents many nosological challenges, since underlying causes and pathogenetics are often not known.[6][7] Therefore, most current textbooks present a classification based on location (for example, conditions of the mucous membrane), morphology (chronic blistering conditions), cause (skin conditions ...
... (also known as "Follicular mucinosis," "Mucinosis follicularis,",[1] "Pinkus' follicular mucinosis,"[1] and "Pinkus' follicular mucinosis-benign primary form"[1]) is a skin disorder that generally presents, but not exclusively, as erythematous plaques or flat patches without hair primarily on the scalp and face.[2]:649[3]:188 This can also present on the body as a follicular mucinosis and may represent a systemic disease.[1][4]. ...
... is a highly inflammatory disease presenting with comedones, nodules, abscesses, and draining sinus tracts.[1][2] This condition generally begins between the ages of 18 and 30. It usually persists for a very long time, and often until the patient is around 40 years old. Although it often occurs where there is already an active acne problem, it can also happen to people whose acne has subsided. Although the cause of this type of acne is unknown, it is associated with testosterone and thus appears mainly in men. It can be caused by anabolic steroid abuse and sometimes appears in men after stopping testosterone therapy. It can also happen to someone who has a tumor that is releasing large amounts of androgens, or to people in remission from diseases, such as leukemia. In certain persons, the condition may be triggered by exposure to aromatic hydrocarbons or ingestion of halogens.[3] ...
... , also known as a "simple sebaceous duct cyst" or "solitary steatocystoma", is a cutaneous condition characterized by a skin lesion that occurs with equal frequency in adult women and men, and is typically found on the face, trunk, or extremities.[1]:679. ...
Hair thinning and baldness cause psychological stress due to their effect on appearance. Although societal interest in appearance has a long history, this particular branch of psychology came into its own during the 1960s and has gained momentum as messages associating physical attractiveness with success and happiness grow more prevalent.[10] The psychology of hair thinning is a complex issue. Hair is considered an essential part of overall identity: especially for women, for whom it often represents femininity and attractiveness. Men typically associate a full head of hair with youth and vigor. Although they may be aware of pattern baldness in their family, many are uncomfortable talking about the issue. Hair thinning is therefore a sensitive issue for both sexes. For sufferers, it can represent a loss of control and feelings of isolation. People experiencing hair thinning often find themselves in a situation where their physical appearance is at odds with their own self-image and commonly ...
... is a disorder of the sebaceous glands in which they become enlarged, producing flesh-colored or yellowish, shiny, often umbilicated bumps on the face.[1] Newly formed nodules often swell with sweating (which is pathognomonic for the condition), but this diminishes over time. Sebaceous glands are glands located within the skin and are responsible for secreting an oily substance named sebum. They are commonly associated with hair follicles but they can be found in hairless regions of the skin as well. Their secretion lubricates the skin, protecting it from drying out or becoming irritated.[2] Sebaceous hyperplasia generally affects newborns as well as middle-aged to elderly adults. The symptoms of this condition are 1-5 mm papules on the skin, mainly on the forehead, nose and cheeks, and seborrheic facial skin. The papules may be cauliflower-shaped. In infants, acne is sometimes associated with sebaceous hyperplasia. ...
... is a rare condition consisting of follicular vesicopustules, sometimes occurring as solitary lesions that are usually very itchy.[1] The condition affects middle aged and elderly individuals. Affected areas can include the scalp, frontal hairline, face, and chest.[2][3] ...
The objective assessment of treatment efficacy is very difficult and spontaneous remission is unpredictable, but if the affected area is patched, the hair may regrow spontaneously in many cases.[18] None of the existing therapeutic options are curative or preventive.[18]. In cases of severe hair loss, limited success has been achieved by using the corticosteroids clobetasol or fluocinonide, corticosteroid injections, or cream. The cream is not as effective and it takes longer in order to see results. Steroid injections are commonly used in sites where the areas of hair loss on the head are small or especially where eyebrow hair has been lost. Whether they are effective is uncertain. Some other medications that have been used are minoxidil, Elocon (mometasone) ointment (steroid cream), irritants (anthralin or topical coal tar), and topical immunotherapy ciclosporin, sometimes in different combinations. Topical corticosteroids frequently fail to enter the skin deeply enough to affect the hair ...
... "chloracne"). It was only in the mid-1950s that chloracne was associated with aromatic hydrocarbons.[2] The substances that may ... 193 cases of chloracne occurred in Seveso, Italy in 1976 following an industrial accident in which up to a few kilograms of ... Chloracne is an acne-like eruption of blackheads, cysts, and pustules associated with over-exposure to certain halogenated ... However, chloracne itself can be highly resistant to any treatment. The course of the disease is highly variable. In some cases ...
Information on chloracne, a skin condition VA recognizes in Veterans as associated with Agent Orange exposure during military ... About chloracne. Chloracne is a rare skin eruption of blackheads, cysts and nodules, which has been linked directly to dioxin ... Chloracne or Acneform Disease and Agent Orange. VA presumes chloracne (or other similar acneform disease) in Veterans is ... VA benefits for chloracne or similar acneform disease. Veterans with chloracne (or other similar acneform disease) that ...
Chloracne. MADISH. Metabolising Aquired Dioxin Induced Skin Hamartomas. Authoritative facts about the skin from DermNet New ... What causes chloracne?. Chloracne is caused by exposure to halogenated aromatic hydrocarbons, which are most often found in:. * ... What is chloracne?. Chloracne is a rare skin condition caused by certain toxic halogenated aromatic hydrocarbon chemicals, ... Most cases of chloracne are due to occupational exposure but chloracne can also arise after accidental environmental poisoning ...
... Agent Orange Presumptive Conditions. VA assumes that certain diseases can be related to a ...
Chloracne is a skin condition caused by exposure to halogenated cyclic hydrocarbons. Features include:. • presence of comedones ... Interesting factoid: Chloracne is the only clinical condition I know of whose treatment has included massive doses of Pringles ... Chloracne: Still Cause for Concern. Passasrini B et al. Dermatology [Published online June 2 2010 ahead of print] ... Chloracne: First manifestation of dioxin toxicity. June 5, 2010, 10:11 pm. ...
Many workers had chloracne. In a NIOSH study in the U.S., the average concentration of TCDD in exposed persons was 233 ng/kg ( ... TCDD concentration in fat was 108,000 pg/g. Also in this case the most prominent symptom was chloracne after initial stomach ... By far the best proven effect is chloracne. The suspected effects in adults are liver damage, and alterations in heme ... The main feature was chloracne, a serious skin disease. The victim survived, and other symptoms were modest after initial ...
In a study conducted by the CDC and the Missouri Division of Health, no cases of chloracne, a common symptom of acute dioxin ... Twelve horses died, and children exposed to the arena were diagnosed with chloracne, a skin condition associated with dioxin ... Suskind, Raymond (1984). "Chloracne, "the hallmark of dioxin intoxication"". Scandinavian Journal of Work, Environment & Health ...
Study Results for Chloracne. Use of CNs during World War I led to the first large outbreaks of chloracne. Chloracne is an acne- ... One of the male deaths was in the chloracne subcohort, where only 0.21 deaths were expected. Neither the male nor the chloracne ... Chloracne is a severe land of acne that results only from certain types of chemical exposures. In the late 1930s, doctors ... Outbreaks of chloracne from CN vapor exposure occurred in the late 1930s and 1940s. 460 cases occurred among workers in the ...
Chloracne. The Reassessment adequately summarizes the uniformly agreed upon and well-documented association between TCDD ... In humans, there is a clear association of TCDD exposure with chloracne and available studies have shown suggestive ...
zone A with chloracne, and 10 with no evidence of chloracne, and 10 from residents of the least contaminated zone. TCDD levels ... Summary for Chloracne. In summary, chloracne has been linked to TCDD exposure in numerous epidemiologic studies of ... Workers were categorized based on current evidence or past history of chloracne (N = 117) versus no current or past chloracne ( ... Of 146 of the original 164 children identified with chloracne, the highest frequency of chloracne was in zone A. In the ...
The cinnamaldehyde-containing Kampo herbal medicine Keishibukuryogan is capable of improving chloracne in Yusho patients who ... and induces hyperkeratinization of keratinocytes and sebocytes leading to chloracne. Nuclear factor-erythroid 2-related factor- ... Chloracne is the major skin symptom caused by dioxin intoxication. Dioxin activates the aryl hydrocarbon receptor (AHR)- ... Potential Role of NRF2 Agonist in Managing AHR-Mediated Chloracne by Dioxin. Masutaka Furue * , Yoko Fuyuno , Chikage Mitoma , ...
Chloracne in this herbicide production worker involved almost every follicular orifice on his face and neck with comedones, ... Slide 22 - Oil Folliculitis Chronic, Chloracne. Chlordane is an extremely refractory type of acne caused by certain halogenated ...
Skin Conditions Qualifying for Presumptive Service Connection Chloracne and Porphyria Cutanea Tarda ... Severe chloracne can lead to open sores and permanent scars.. Causes: Chloracne is caused by certain types of toxic chemicals, ... Chloracne. Chloracne is a rare skin condition consisting of blackheads, cysts, and nodules. It can look like teenage acne, and ... but not everyone exposed to a toxic chemical like dioxin will develop chloracne. Chloracne does not develop years later. ...
Chloracne. Chloracne is an acne-like eruption of blackheads, cysts, and pustules associated with over-exposure to certain ... chloracne). It was only in the mid-1950s that chloracne was associated with aromatic hydrocarbons[5]. The substances that may ... However, chloracne may be highly resistant to any treatment. Acne fulminans. Acne fulminans (acne maligna) is a rare and severe ... Once chloracne has been identified, the primary action is to remove the patient and all other individuals from the source of ...
Chloracne: Skin rashes, open sores, redness, discoloration of the skin, cysts, boils, etc.. PTSD (Post Traumatic Stress ...
Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. EMBO molecular medicine. 2014 Apr 1;6( ... Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. Publikationen: Beitrag in ... Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. / Schäfer, Matthias; Willrodt, Ann- ... These alterations were highly reminiscent to the phenotype of chloracne/{"}metabolizing acquired dioxin-induced skin hamartomas ...
Chloracne. Plewig, Prof. Dr. med. Gerd (et al.). Pages 400-419 Preview Buy Chapter $29.95 ...
Chloracne: A rash of skin lesions on the face, neck, and back caused by exposure to TCDD. ... and chloracne. Porphyria cutanea tarda (a rare skin disease) was downgraded from sufficient to "limited/suggestive evidence of ... 5-T is manufactured have developed a condition called chloracne, a rash of skin lesions on the face, neck, and back. After ... the number of chloracne cases among factory workers in the herbicide industry decreased substantially. ...
Chloracne, "the hallmark of dioxin intoxication". Scand J Work Environ Health. 1985;11:165-71.CrossRefPubMedGoogle Scholar ... Ju Q, Zouboulis CC, Xia L. Environmental pollution and acne: chloracne. Dermatoendocrinol. 2009;1(3):125-8.CrossRefPubMed ... Chloracne Acne variant associated with exposure to environmental pollutants that develops after systemic poisoning by ... Dioxin-induced chloracne - reconstructing the cellular and molecular mechanisms of a classic environmental disease. Exp ...
Chloracne on the Neck. Another kind of acne that appears on the neck is chloracne, acne that is caused by exposure to chemicals ... Chloracne is a common problem in China.. Chloracne was first observed in Germany when it was developing its chemical industry ... People with light hair color are especially susceptible to chloracne.. This form of neck acne usually starts at the sides of ... There is no cure for chloracne, but two to three years without further toxin exposure will give the skin time to heal. ...
The best proven is chloracne.[2] Even in poisonings with huge doses of TCDD, the only persistent effects after the initial ... Many workers had chloracne. In a NIOSH study in the U.S., the average concentration of TCDD in exposed persons was 233 ng/kg ( ... malaise have been chloracne and amenorrhea.[17][18] In occupational settings many symptoms have been seen, but exposures have ...
Polycyclic Aromatic Hydrocarbons (PAHs): Assessment and Posttest Instructions
Chloracne.. Schlessinger DI, Schlessinger J.. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.. ...
Chloracne,. *Urticaria, and. *Malignant neoplasms [Levy BS and Wegman DH 2011].. Children appear particularly at risk for ...
"Anogenital region" is an anatomic area that may be affected by chloracne (DC 7829), whereas "pruritus ani" is an itching near ...
Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. ...
Chloracne. Chloracne is a rare acne-like skin condition caused by exposure to halogenated aromatic hydrocarbons (such as ...
Department of Veterans Affairs has begun distributing disability benefits to Vietnam Veterans who qualify for compensation for Agent Orange exposure
... claimed as chloracne, to include as due to exposure to herbicide agents. 2. Entitlement… ... On examination, the Veteran had no rash, hives, or chloracne. The examiner noted that the Veteran was treated for dishydrotic ... The examiner also noted no history or documented evidence of chloracne. At a March 2017 VA examination, the examiner noted that ... The examiner reported that the Veteran did not have a skin condition, including chloracne. The Board finds that the ...
Dioxin toxicity and chloracne in the Ukraine. J Drugs Dermatol. 2005 Mar-Apr. 4(2):148-50. [Medline]. ...
  • However, not all persons exposed to dioxin develop chloracne. (va.gov)
  • Even at relatively high doses, not all exposed individuals develop chloracne, whereas others with similar or lower exposure demonstrate the condition. (nap.edu)
  • People can get chloracne from an occupational or environmental exposure, but not everyone exposed to a toxic chemical like dioxin will develop chloracne. (va.gov)
  • There are people who develop chloracne after swimming in over-chlorinated swimming pools. (facingacne.com)
  • 193 cases of chloracne occurred in Seveso , Italy in 1976 following an industrial accident in which up to a few kilograms of TCDD were released into the atmosphere. (wikipedia.org)
  • Most cases of chloracne are due to occupational exposure but chloracne can also arise after accidental environmental poisoning. (dermnetnz.org)
  • One hundred and ninety-three cases of chloracne resulted from an industrial accident in Seveso, Italy in 1976. (dermnetnz.org)
  • Now that Chinese companies make the majority of the world's chlorinated phenols, polychlorinated biphenyls (PCBs), chloronaphthalenes, and other polychlorinated compounds, such as polychlorinated dibenzo-p-dioxins, polyhalogenated dibenzofurans, and chlorinated azo- and azoxybenzenes, the greatest number of cases of chloracne occur in China. (facingacne.com)
  • Chloracne is an acne -like eruption of blackheads , cysts , and pustules associated with over-exposure to certain halogenated aromatic compounds , such as chlorinated dioxins and dibenzofurans . (wikipedia.org)
  • Chloracne is a rare skin eruption of blackheads, cysts and nodules, which has been linked directly to dioxin exposure . (va.gov)
  • This process alters gene expression in the sebaceous glands and changes them from functioning grease-producing glands into the skin cysts ( hamartomas ) of chloracne. (dermnetnz.org)
  • Chloracne is characterized by persistent comedones, keratin cysts, and inflamed papules. (nap.edu)
  • Chloracne is a rare skin condition consisting of blackheads, cysts, and nodules. (va.gov)
  • With chloracne, toxic chemicals concentrate in these glands, break down slowly, and change the skin glands into cysts. (va.gov)
  • VA presumes chloracne (or other similar acneform disease) in Veterans is related to their exposure to Agent Orange or other herbicides during military service when the disease appears within one year of exposure to Agent Orange to a degree of at least 10 percent disabling by VA's rating regulations. (va.gov)
  • Veterans with chloracne (or other similar acneform disease) that appeared within one year of exposure to herbicides during service to a degree of at least 10 percent disabling by VA's rating regulations may be eligible for disability compensation and health care . (va.gov)
  • Surviving spouses, dependent children and dependent parents of Veterans who were exposed to herbicides during military service and died as the result of chloracne (or other similar acneform disease) may be eligible for survivors' benefits . (va.gov)
  • The Veterans Administration gives disability payments to those with the skin disease chloracne, soft-tissue sarcoma, non-Hodgkins lymphoma and a liver disorder. (chicagotribune.com)
  • The Agent Orange Act of 1991 accepted a presumed link to illnesses like non-Hodgkin's lymphoma, soft-tissue sarcoma and chloracne. (nytimes.com)
  • Chloracne is very often seen in combination with hyperhidrosis (clammy, sweaty skin) and porphyria cutanea tarda (a skin condition of increased pigmentation, hair coarsening and blistering). (wikipedia.org)
  • The sections in this chapter of other health outcomes include chloracne, porphyria cutanea tarda, other metabolic and digestive disorders (diabetes mellitus, alterations in hepatic enzymes, lipid abnormalities, and gastrointestinal ulcers), immune system disorders (immune modulation, autoimmunity), and a number of circulatory and respiratory disorders. (nap.edu)
  • Two skin conditions, chloracne and porphyria cutanea tarda, may be related to exposure to Agent Orange during the Vietnam War. (va.gov)
  • Exposure to dioxin is associated with chloracne and porphyria cutanea tarda. (thefreedictionary.com)
  • Very low level dioxin and dioxin-like aromatic hydrocarbons are ubiquitous in the environment but standard environmental exposure does not result in chloracne. (dermnetnz.org)
  • sufficient exposure, whether by inhalation of vapors or skin contact, can result in chloracne which I think we must assume could be an indication of a more systemic injury if the exposure were allowed to continue. (rachel.org)
  • Chloracne in this herbicide production worker involved almost every follicular orifice on his face and neck with comedones , papules and cystlike lesions. (wikipedia.org)
  • Most chloracne lesions clear up within 2 years providing exposure to the chemical has stopped. (dermnetnz.org)
  • Because acne is such a common dermatologic condition, in any analysis attempting to link acne or chloracne with an environmental or occupational exposure, it is critical that adequate attention be paid to the clinical characteristics, time of onset, and distribution of lesions, as well as careful comparison with an appropriate control group. (nap.edu)
  • TCDD is a by-product of the manufacture of trichlorophenol, a chemical used to produce 2,4,5-T. Workers involved in accidents or spills at factories where the herbicide 2,4,5-T is manufactured have developed a condition called chloracne, a rash of skin lesions on the face, neck, and back. (encyclopedia.com)
  • Chloracne is a severe skin disease with acne-like lesions that occur mainly on the face and upper body. (cdc.gov)
  • Chloracne is particularly linked to toxic exposure to dioxins ( byproducts of many chemical processes , including the manufacture of herbicides such as Agent Orange )-so much so that it is considered a clinical sign of dioxin exposure. (wikipedia.org)
  • This presentation of nine cases and clinical discussion, from the University of Bologna, points out that chloracne can be the first sign of dioxin exposure, and thus it is important not to miss the diagnosis. (thepoisonreview.com)
  • About 43% of patients had chloracne, known to be caused by dioxin exposure. (salem-news.com)
  • In 1936 a senior official with the U.S., Public Health Service described a wife and child, both of whom had developed chloracne, a combination of blackheads and "pustules," merely from contact with a worker's clothes. (rachel.org)
  • [2] The substances that may cause chloracne are now collectively known as chloracnegens . (wikipedia.org)
  • Among the numerous industrial chemicals known to cause chloracne, the most potent appears to be TCDD. (nap.edu)
  • Another kind of acne that appears on the neck is chloracne, acne that is caused by exposure to chemicals containing chlorine. (facingacne.com)
  • The Health and Medicine Division (formally known as the Institute of Medicine) of the National Academy of Sciences, Engineering, and Medicine concluded in its 1994 report on " Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam ", as well as in its 2014 update and previous updates, that there is a positive association between chloracne and exposure to dioxin in Agent Orange. (va.gov)
  • When CNs were first used, high exposures caused chloracne and acute yellow atrophy of the liver to develop very quickly. (cdc.gov)
  • In humans, severe skin reactions (chloracne) and liver disease have both been reported after occupational exposure to PCNs. (ewg.org)
  • Forty-three percent of the veterans had chloracne, a skin condition specifically caused by exposure to dioxins. (medindia.net)
  • Certain groups appear to be at particularly high risk, including veterans actively involved in spraying Agent Orange, those with chloracne, and those with lighter skin types. (medindia.net)
  • Chloracne is a severe land of acne that results only from certain types of chemical exposures. (cdc.gov)
  • Based on the results of physical examinations, clinical laboratory studies, observed work practices, a pertinent literature review, and environmental sampling, definite toxic exposures resulting in chloracne from pentachlorophenol (PCP) (87865) contaminants are determined to occur in the Weyerhaeuser Treating Plant (SIC-4226), De Queen, Arkansas. (cdc.gov)
  • Chloracne is a rare skin condition caused by certain toxic halogenated aromatic hydrocarbon chemicals, including the dioxins. (dermnetnz.org)
  • Chloracne is a rare acne-like skin condition caused by exposure to halogenated aromatic hydrocarbons (such as dioxins). (greenfacts.org)
  • Chloracne is a type of acne that is associated with overexposure to dioxins. (emaxhealth.com)
  • Chloracne is the major skin symptom caused by dioxin intoxication. (preprints.org)
  • The cinnamaldehyde-containing Kampo herbal medicine Keishibukuryogan is capable of improving chloracne in Yusho patients who are highly contaminated with dioxin. (preprints.org)
  • Severe chloracne may lead to open sores and permanent scars. (va.gov)
  • Chloracne is a well established, long-term effect of exposure to TCDD or dioxin, a contaminant in Agent Orange. (va.gov)
  • However, the only dermatologic disorder consistently reported to be associated with Agent Orange or its components, including the contaminant, TCDD (2,3,7,8-tetrachlorodibenzo- p -dioxin), is chloracne. (nap.edu)
  • Therefore, this discussion will focus on chloracne and its link to TCDD. (nap.edu)
  • the major issue of current concern is the precise dose-response relationship between TCDD exposure by various routes (dermal, inhalation, ingestion) and the occurrence of chloracne. (nap.edu)
  • After researchers developed a method to produce trichlorophenol with a reduced level of TCDD as a by-product, the number of chloracne cases among factory workers in the herbicide industry decreased substantially. (encyclopedia.com)
  • The most noted health effect in people exposed to large amounts of 2,3,7,8-TCDD is chloracne. (cdc.gov)
  • The most commonly observed health effects in people exposed to PCBs are skin conditions such as chloracne and rashes, but these were known to be symptoms of systemic poisoning dating back to the 1922. (politics.ie)
  • Chloracne is caused by certain types of toxic chemicals, including dioxin, a contaminant found in Agent Orange. (va.gov)
  • Entitlement to service connection for a skin disability, claimed as chloracne, to include as due to exposure to herbicide agents. (va-claim.com)
  • Agent Orange, a 1:1 mixture of 2,4,-D and 2,4,5-T, was the most prevalent herbicide used ( http://www.agentorangerecord.com/home/ and http://en.wikipedia.org/wiki/Agent_Orange ). (salem-news.com)
  • As with many dermatologic conditions, chloracne can reasonably be suspected on the basis of a careful medical history or appropriate questionnaire information. (nap.edu)
  • Dioxin activates the aryl hydrocarbon receptor (AHR)-cytochrome p450 1A1 (CYP1A1) system, generates oxidative stress, and induces hyperkeratinization of keratinocytes and sebocytes leading to chloracne. (preprints.org)
  • Chloracne is a chronic inflammatory condition that results from this persistence, in combination with the toxin's chemical properties. (wikipedia.org)
  • In 1968, almost 2,000 individuals in northern Kyūshū , Japan suffered chloracne, among other symptoms, after chronic exposure to cooking oils contaminated with PCBs and PCDFs . (wikipedia.org)
  • These alterations were highly reminiscent to the phenotype of chloracne/{"}metabolizing acquired dioxin-induced skin hamartomas{"} (MADISH) patients. (dshs-koeln.de)
  • Doctors have known since World War I that chlorinated naphthalenes CNs) can cause the acne-like skin disease chloracne. (cdc.gov)
  • Chloracne was first described in relation to occupational exposure among chemical industry workers by Von Vettman in 1887 (AFHS, 1991b) and was first linked to the specific chemical trichlorophenol in 1957 (Crow and Puhvel, 1991). (nap.edu)
  • Chloracne normally results from direct skin contact with chloracnegens, although ingestion and inhalation are also possible causative routes. (wikipedia.org)
  • As these systemic symptoms abate, the skin changes begin, and this is when the diagnosis of chloracne may become more obvious. (dermnetnz.org)
  • it has a tremendous potential for producing chloracne and systemic injury. (thewe.cc)
  • Chlorinated chemicals can cause a particularly bad form of acne called chloracne . (scienceline.org)
  • Once chloracne has been identified, the primary action is to remove the patient and all other individuals from the source of contamination. (wikipedia.org)
  • Tsuji, G. Therapeutic Agents with AHR Inhibiting and NRF2 Activating Activity for Managing Chloracne. (preprints.org)
  • The severity and onset of chloracne may follow a typical asymptotic dose-response relationship curve . (wikipedia.org)
  • Note: some conditions such as chloracne and peripheral neuropathy (early onset) have to occur within certain periods after possible Agent Orange exposure to be considered presumptive conditions. (va.gov)