Chloracne
Acne Vulgaris
Dioxins
Tetrachlorodibenzodioxin
Repression of aryl hydrocarbon receptor transcriptional activity by epidermal growth factor. (1/4)
(+info)Inflammatory and chloracne-like skin lesions in B6C3F1 mice exposed to 3,3',4,4'-tetrachloroazobenzene for 2 years. (2/4)
(+info)Proceedings of the 2010 National Toxicology Program Satellite Symposium. (3/4)
(+info)Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down. (4/4)
(+info)
Chloracne - Wikipedia
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Chloracne
The substances that may cause chloracne are now collectively known as chloracnegens. Chloracne is particularly linked to toxic ... The severity and onset of chloracne may follow a typical asymptotic dose-response relationship curve. Chloracne normally ... "chloracne"). It was only in the mid-1950s that chloracne was associated with aromatic hydrocarbons. ... Once chloracne has been identified, the primary action is to remove the patient and all other individuals from the source of ...
Dioxins and dioxin-like compounds
Many workers had chloracne. In a NIOSH study in the U.S., the average concentration of TCDD in exposed persons was 233 ng/kg ( ... TCDD concentration in fat was 108,000 pg/g. Also in this case the most prominent symptom was chloracne after initial stomach ... By far the best proven effect is chloracne. The suspected effects in adults are liver damage, and alterations in heme ... The main feature was chloracne, a serious skin disease. The victim survived, and other symptoms were modest after initial ...
2,6-Dichlorobenzonitrile
This may result in chloracne." Further, it has advised The substance is toxic to aquatic organisms. This substance does enter ...
Polychlorinated biphenyl
... such as chloracne and rashes, but these were known to be symptoms of acute systemic poisoning dating back to 1922. Studies in ... chloracne); liver, stomach, and thyroid gland injuries (including hepatocarcinoma),[citation needed] and thymocyte apoptosis. ...
Times Beach, Missouri
In a study conducted by the CDC and the Missouri Division of Health, no cases of chloracne, a common symptom of acute dioxin ... Twelve horses died, and children exposed to the arena were diagnosed with chloracne, a skin condition associated with dioxin ... Suskind, Raymond (1984). "Chloracne, "the hallmark of dioxin intoxication"". Scandinavian Journal of Work, Environment & Health ...
2,3,7,8-Tetrachlorodibenzodioxin
He suffered from chloracne for many years, but after initial malaise, other symptoms or abnormal laboratory findings were few. ... The acute effects were limited to about 200 cases of chloracne. Long-term effects seem to include a slight excess of multiple ... They survived but suffered from difficult chloracne for several years. The poisoning likely happened in October 1997 but was ...
Seveso disaster
A study published in 1998 concluded that chloracne (nearly 200 cases with a definite exposure dependence) was the only effect ... The most evident adverse health effect ascertained was chloracne (193 cases). Other early effects noted were peripheral ... and chloracne sufferers (1985) The documentary Gambit is about Jörg Sambeth, the technical director of ICMESA, who was ... 447 were found to suffer from skin lesions or chloracne. An advice center was set up for pregnant women, of whom 26[citation ...
2,4,5-Trichlorophenoxyacetic acid
Six workers that cleaned up afterwards got seriously intoxicated and developed chloracne. After twelve years, four of the six ...
Endocrine disruptor
Direct skin contact results in a severe acne-like condition called chloracne. Exposure increases the risk of skin cancer, liver ... c-fos and TGF-alpha in skin lesions from dioxin-exposed humans with chloracne" (PDF). Toxicol. Lett. 177 (3): 182-7. doi: ...
Abietic acid dermatitis
Contact dermatitis Chloracne List of cutaneous conditions Bolognia JL, Schaffer JV, Cerroni L (2017). Dermatology E-Book. ...
2019-2020 Hong Kong protests
The use of tear gas sparked public health concerns after a reporter was diagnosed with chloracne in November 2019, though both ... "Hong Kong reporter diagnosed with chloracne after tear gas exposure, prompting public health concerns". Hong Kong Free Press. ...
Police misconduct allegations during the 2019-2020 Hong Kong protests
A reporter was diagnosed with chloracne, a condition associated with over-exposure to dioxins, following sustained exposure to ... "Hong Kong reporter diagnosed with chloracne after tear gas exposure, prompting public health concerns". Hong Kong Free Press. ...
List of industrial disasters
In addition, 193 people in the affected areas suffered from chloracne and other symptoms. The disaster lead to the Seveso ...
Polychlorinated dibenzodioxins
She suffered from chloracne, nausea, vomiting, epigastric pain, loss of appetite, leukocytosis, anemia, amenorrhoea and ... known as chloracne. High occupational or accidental levels of exposures to dioxins have been shown by epidemiological studies ... and was diagnosed only after a toxicologist recognized the symptoms of chloracne while viewing television news coverage of his ... who apparently suffered no notable negative effects other than chloracne. These patients were provided with olestra to ...
Fred A. Wilcox
The conditions include Hodgkin's lymphoma, chloracne, severe birth-defects and various types of cancer, among others. About the ...
2,2',3,3',4,4'-Hexachlorobiphenyl
They may cause a rash when in contact with the skin and prolonged exposure can result in chloracne. High exposure to PCBs can ...
Acne
Chloracne and occupational acne due to exposure to certain chemicals & industrial compounds, may look very similar to acne ...
Coalite
79 employees contracted chloracne whilst cleaning up and even some of their families were affected by traces brought home on ...
Holmesburg Prison
In many cases, excessive doses would produce chloracne, inflammatory pustules, and papules which lasted four to seven months at ...
Heptachlorodibenzo-p-dioxin
Chloracne, an acne-like eruption of blackheads, cysts, and pustules, is associated with exposure to pentachlorophenol ...
Persistent organic pollutant
Dioxins have been associated with several adverse effects in humans, including immune and enzyme disorders, chloracne, and are ...
Viktor Yushchenko
Dutch toxicologist Bram Brouwer also stated his changes in appearance were the result of chloracne, and found dioxin levels in ... Professor John Henry of St Mary's Hospital in London declared the changes in Yushchenko's face were due to chloracne, which ...
Unethical human experimentation in the United States
... because workers at its chemical plants were developing chloracne. In the study, Kligman applied about the same amount of dioxin ...
List of skin conditions
... deodorant-induced Baboon syndrome Black dermatographism Bleaching cream-induced Capsaisin-induced Chemical burn Chloracne ...
Agent Orange Act of 1991
... chloracne, and consistent acneform diseases for military personnel who served in the overseas Vietnamese region. The Act of ...
Inochi No Chikyuu: Dioxin No Natsu
Too much time has passed since the initial contamination, and many inhabitants, including Maria, contract chloracne, as much as ...
Acne (disambiguation)
... and forehead of infants Blackheads Chloracne, an acne-like eruption of blackheads, cysts, and pustules associated with exposure ...
Vietnam War
... chloracne, porphyria cutanea tarda, peripheral neuropathy and spina bifida in children of veterans exposed to Agent Orange. ...
CS gas
A Hong Kong journalist, Chan Yu-hong from the Stand News declared he was diagnosed with chloracne (by a Traditional Chinese ...
Halocarbon
... manufacturing suffering from chloracne (Teleky 1927), and by the late 1930s it was known that workers exposed to PCNs could die ...
What is Chloracne? (with pictures)
Chloracne is a rare condition in which a person develops severe acne after exposure to certain toxic chemicals. Risk factors ... Chloracne was once believed to be caused by exposure to chlorine. With or without treatment, most chloracne legions clear up ... Overexposure to toxic chemicals may cause chloracne. The first signs of chloracne generally appear within three to four weeks ... Pustules that appear as a result of chloracne may be cauterized. Patients exhibiting signs of chloracne may experience other ...
Worker Health Study Summaries - Navy Cable Manufacturers | NIOSH | CDC
Study Results for Chloracne. Use of CNs during World War I led to the first large outbreaks of chloracne. Chloracne is an acne- ... One of the male deaths was in the chloracne subcohort, where only 0.21 deaths were expected. Neither the male nor the chloracne ... Chloracne is a severe land of acne that results only from certain types of chemical exposures. In the late 1930s, doctors ... Outbreaks of chloracne from CN vapor exposure occurred in the late 1930s and 1940s. 460 cases occurred among workers in the ...
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Chlorinated Dibenzo-p-dioxins (CDDs) | Public Health Statement | ATSDR
Chloracne is a severe skin disease characterized by acne-like lesions. Chloracne generally occurs on the face and upper body, ... Most of the chloracne cases have been attributed to accidental exposure to high doses of 2,3,7,8-TCDD. Other effects to the ... Chloracne has been observed in children exposed to much higher than current background levels of 2,3,7,8-TCDD. The children ... Unlike common acne, severe chloracne is harder to cure and can be more disfiguring. In milder cases, the lesions heal several ...
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The exception is chloracne, which occurred in employees who experienced very high exposure levels, with temporary effects.. ... After an outbreak of chloracne, the health of these employees has been followed for more than 60 years - longer than any other ... After an outbreak of chloracne, the health of these employees has been followed for more than 60 years - longer than any other ... Results show no indication of increased trends of disease related to dioxin exposure, with the exception of chloracne. Of those ...
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LiverPorphyriaAcneDioxinAlterationsNeurologicalIschemicAcuteChlorineOccupationalTemporarySkin conditionPatientsWorkersDevelopSimilarChemicalDiseaseResultPorphyria CutanSevereFolliculitisDioxinsDiabetesNuchaeCancersSymptomsAcneformHumansDermatitisCaused by chemical exposureImmuneLiver functionConditionAgent OrangeCystPCBsAromaticFormEffectsFunctionsCase
Liver8
- When CNs were first used, high exposures caused chloracne and acute yellow atrophy of the liver to develop very quickly. (cdc.gov)
- In humans, severe skin reactions (chloracne) and liver disease have both been reported after occupational exposure to PCNs. (ewg.org)
- Chemical workers exposed to PCBs developed chloracne, a severe skin abnormality, and liver disorders. (triumvirate.com)
- Indeed, chloracne may actually be a protective mechanism against liver toxicity. (seakexperts.com)
- PCBs are a carcinogen and can cause liver damage and a skin condition "chloracne. (midwestlamprecycling.com)
- But one of the physicians who worked in the specific areas of liver diseases and porphyria testified that Thompson's porphyria was related to his alcohol consumption, and he excluded dioxin as causing Thompson's porphyria because Thompson did not develop chloracne. (quimbee.com)
- Short-term exposure could cause liver problems, chloracne - a type of acne-related skin disease, and darkening of the skin. (stmuscholars.org)
- While the degree of carcinogenic risk could not be determined, the report identifies the main symptoms of occupational exposure as irritation of the eye, nose and airway, dermatitis, chloracne, porphyria, abnormal liver function tests, changes in brain wave activity, and slowed visual reaction time. (who.int)
Porphyria5
- Twenty-nine patients working in a chemical factory engaged in the manufacture of 2,4-dichlorophenol (2,4-D) and 2,4,5-trichlorophenol (2,4,5-T) exhibiting features of chloracne were studied for the presence of porphyria cutanea tarda. (jamanetwork.com)
- Two of these patients who showed evidence of acquired porphyria with chloracne were hospitalized. (jamanetwork.com)
- The features of chloracne as well as the clinical and laboratory features of acquired porphyria have been discussed. (jamanetwork.com)
- There appeared to be an etiologic but not quantitative relationship between the chloracne in workers engaged in the manufacture of 2,4-D and 2,4,5-T and porphyria cutanea tarda of the acquired type. (jamanetwork.com)
- This expert further testified Thompson's symptoms were not consistent with dioxin-induced porphyria because in all previous cases of dioxin-induced porphyria, chloracne accompanied the porphyria, yet Thompson never suffered from chloracne. (quimbee.com)
Acne4
- Common acne medications or oral antibiotics may also be effective in treating chloracne. (wise-geek.com)
- Doctors have known since World War I that chlorinated naphthalenes CNs) can cause the acne-like skin disease chloracne. (cdc.gov)
- Chloracne is a severe land of acne that results only from certain types of chemical exposures. (cdc.gov)
- Exposure to dangerous chemicals called dioxins can cause a rare form of acne called chloracne. (yourdictionary.com)
Dioxin1
- Damages were permanent and only later, John Henry, an English toxicologist from St Mary's Hospital in London, said that chloracne had caused those scars, due to dioxin poisoning, which, in fact, was found in his blood. (resetdoc.org)
Alterations1
- Of the many non-cancer health effects thought to be associated with 2,3,7,8-TCDD exposure, only chloracne, elevations in GGT and triglyceride levels, and alterations in FSH and LH were related to serum 2,3,7,8-TCDD levels. (cdc.gov)
Neurological1
- Ingestion of PCB residue-contaminated food, especially meat, fish and poultry may result in neurological disorders, chloracne and immune and carcinogenic effects. (environ.news)
Ischemic2
- Certain cancers, chloracne, diabetes mellitus kind 2, ischemic coronary heart disease, and other medical situations are linked to Agent Orange publicity. (starprogram.net)
- Certain cancers, chloracne, diabetes mellitus sort 2, ischemic heart illness, and other medical conditions are linked to Agent Orange exposure. (starprogram.net)
Acute1
- These chemicals pose a threat to human health when found in high concentrations that may lead to acute hepatoxicity and dermal toxicity (chloracne). (nwu.ac.za)
Chlorine1
- Chloracne was once believed to be caused by exposure to chlorine. (wise-geek.com)
Occupational1
- These may induce the occupational skin disorder known as chloracne. (hasenchat.eu)
Temporary1
- The only consistently demonstrated health effect in these highly exposed populations has been chloracne - a temporary skin condition which can be severe in some cases. (dow.com)
Skin condition1
- Chloracne is a rare skin condition caused by over-exposure to certain toxic chemicals. (wise-geek.com)
Patients1
- Patients exhibiting signs of chloracne may experience other skin conditions, such as sweaty palms and soles, as well as pigmentation, increased hair growth, and blisters on exposed skin. (wise-geek.com)
Workers2
- Personal protective equipment can be worn by industrial workers at risk for developing chloracne. (wise-geek.com)
- A number of workers at herbicide plants at that time suffered a disfiguring skin disease called chloracne. (seakexperts.com)
Develop1
- In the event of massive exposure, chloracne can develop within days. (wise-geek.com)
Similar1
- Chloracne or similar acneform disease with similar symptoms to chloracne. (vetsnational.com)
Chemical2
- Chloracne is most commonly associated with exposure to dioxins , or byproducts from certain chemical processes such as the manufacture of herbicides. (wise-geek.com)
- VA conceded that chloracne, skin lesions caused by chemical exposure, was connected to Agent Orange exposure in 1978. (veteransvoices.net)
Disease1
- More than a decade after the war's end, only one illness-the disfiguring skin disease chloracne-was offically recognized as connected to wartime Agent Orange exposure. (motherjones.com)
Result1
- Pustules that appear as a result of chloracne may be cauterized. (wise-geek.com)
Porphyria Cutan1
- Health Survey of Workers in a 2,4-D and 2,4,5-T Plant: With Special Attention to Chloracne, Porphyria Cutanea Tarda, and Psychologic Parameters. (epa.gov)
Severe5
- Chloracne, a skin disease with severe acne-like pimples. (weitzlux.com)
- Chloracne is very severe and doesn't have a cure. (bestdailyguide.com)
- The adverse health effects include a severe form of acne (chloracne), swelling of the upper eyelids, discolouring of the nails and skin, numbness in the arms and/or legs, weakness, muscle spasms, chronic bronchitis, and problems related to the nervous system. (lifelabs.com)
- Exposure to high levels of chlorine compounds, particularly chlorinated dioxins, can cause severe, long-lasting acne, known as Chloracne. (shaml-blog.com)
- Exposure to certain chemicals (e.g., dioxin and other halogenated hydrocarbons) that are found in herbicides and other industrial products can cause severe inflammatory acne-type reactions (chloracne) and scarring. (pcrm.org)
Folliculitis2
- Rule out dermatologic disorders such as excoriated lesions of folliculitis, acne necrotica, Dowling-Degos disease, or chloracne. (thecardiologyadvisor.com)
- Isotretinoin may also be used for some other conditions that include- folliculitis, seborrhoea, chloracne and other diseases that look like acne. (backingseo.com)
Dioxins3
- Exposure to high concentrations of especially toxic dioxins can cause an acne-like condition known as chloracne which mainly affects the face and upper body, which may last several years after exposure. (findmeacure.com)
- Chloracne is a rare acne-like skin condition caused by certain toxic chemicals including the dioxins. (blogs.com)
- Dioxins have been associated with a number of adverse effects in humans, including immune and enzyme disorders and chloracne, and they are classified as possible human carcinogens. (ipen-china.org)
Diabetes1
- Additionally, dioxin exposure has been linked to some other diseases, including type 2 Diabetes, Ischemic Heart Disease, and an acne-like skin disease called Chloracne. (thehillbillyshaman.com)
Nuchae1
- There are six types of acne: Acne Rosacea, Acne Cosmetica, Acne Fulminans, Acne Keloidalis Nuchae (AKN), Acne Chloracne and Acne Medicamentosa. (marketresearch.com)
Cancers3
- The dioxin in AO is believed to be the cause of birth defects, liver cancers, chloracne and other health problems in southern Vietnam since the end of the war. (greenleft.org.au)
- Dioxin has been found to be an endocrine disruptor that can cause chloracne, certain cancers, and reproductive and developmental effects (at least in animals). (agentorangerecord.com)
- Adverse health effects linked to PCB exposure include skin conditions such as chloracne, lowered immune response, and possible cancers of the liver and biliary tract in humans among other concerns. (ironmagazine.com)
Symptoms1
- Poisoning by high concentrations of dioxin and its related compounds manifests variable toxic symptoms such as general malaise, chloracne, hyperpigmentation, sputum and cough, paresthesia or numbness of the extremities, hypertriglyceridemia, perinatal abnormalities, and elevated risks of cancer-related mortality. (nih.gov)
Acneform1
- Chloracne (or other types of acneform disease like it): A skin condition that happens soon after contact with chemicals and looks like acne often seen in teenagers. (healthtopquestions.com)
Humans2
- 6. Expression of AhR, CYP1A1, GSTA1, c-fos and TGF-alpha in skin lesions from dioxin-exposed humans with chloracne. (nih.gov)
- Short-term exposure of humans to high levels of UPOPs may result in skin lesions such as chloracne, patchy darkening of the skin, and altered liver function. (stopthepops.com)
Dermatitis1
- Repeated or prolonged contact with skin may cause dermatitis including chloracne. (inchem.org)
Caused by chemical exposure2
- In patients exhibiting chloracne, a specific skin disorder caused by chemical exposure, the causative compounds may be detected both in adipose tissue and in sebum of the skin. (digitalnaturopath.com)
- VA conceded that chloracne, skin lesions caused by chemical exposure, was connected to Agent Orange exposure in 1978. (veteransvoices.net)
Immune1
- PCB exposure in the womb or during lactation is also associated with decreased IQ and impaired psychomotor development, decreased immune function, altered liver enzyme and lipid levels, and skin disease (chloracne) (ATSDR 2000b). (ewg.org)
Liver function1
- High-level exposure to selected organochlorines appears to cause abnormalities of liver function, skin (chloracne), and the nervous system. (nih.gov)
Condition4
- Chloracne, a serious skin condition consisting of lesions, can also result from high exposures to dioxin. (treehugger.com)
- Until the 1990s, the government recognized only one ailment - a skin condition called chloracne - as being linked to Agent Orange. (aarp.org)
- Abstract Chloracne has been a troublesome condition to treat in our experience. (deepdyve.com)
- Chloracne is the skin condition that disfigured Ukraine's president, Victor Yushchenko, after he was poisoned by a large dose of dioxin. (environmentreport.org)
Agent Orange3
- In order to qualify for benefits, the following conditions must become noticeable to a degree of 10 percent or more within one year of the last date of exposure to Agent Orange: Chloracne. (proceedings-szh.com)
- There is a direct link between exposure to herbicides like Agent Orange and chloracne. (sluiceartfair.com)
- The Chloracne was diagnosed by the Agent Orange Registry Exam and a letter wriiten to me my the examining DR saying it was presumptive of exposure to Agent Orange. (hadit.com)
Cyst1
- Chloracne-like sebaceous gland hypoplasia and cyst formation were observed in TCDD-exposed P21 mice, with concomitant microbiome dysbiosis. (memphis.edu)
PCBs2
Aromatic2
- Group 3 - halogenated aromatic compounds, like polychlorinated biphenyls, cause chloracne. (eco-pro-beauty.com)
- Chloracne is caused by systemic exposure to certain halogenated aromatic hydrocarbons 'chloracnegens', and is considered to be one of the most sensitive indicators of systemic poisoning by these compounds. (sheslookingatthestars.com)
Form2
- Dioxin, used to poison the Ukrainian politician Viktor Yushchenko in 2004, is also responsible for a form of acne called chloracne . (opednews.com)
- Dow researcher Jim Collins says the company has six decades of research on employees who've been exposed to high levels of dioxin, and the worst health effect is a mild form of chloracne in some of the company's employees. (environmentreport.org)
Effects1
- And other than some increased risk of chloracne in these workers, we find no health effects that have been related to dioxin exposures. (environmentreport.org)
Functions2
- 18. Toward elucidation of dioxin-mediated chloracne and Ah receptor functions. (nih.gov)
- These direct grounds are Here engaging with the download manual de perforación manual de pozos, and are inland be Chloracne of the functions published in related case. (mandolinenclubtrier-biewer.de)
Case1
- 3. Chloracne: a case series on cutaneous expression of CYP1A1 as diagnostic biomarker. (nih.gov)