Chlamydophila pneumoniae: A species of CHLAMYDOPHILA that causes acute respiratory infection, especially atypical pneumonia, in humans, horses, and koalas.Chlamydophila Infections: Infections with bacteria of the genus CHLAMYDOPHILA.Chlamydophila: A genus of the family CHLAMYDIACEAE comprising gram-negative non CHLAMYDIA TRACHOMATIS-like species infecting vertebrates. Chlamydophila do not produce detectable quantities of glycogen. The type species is CHLAMYDOPHILA PSITTACI.Mycoplasma pneumoniae: Short filamentous organism of the genus Mycoplasma, which binds firmly to the cells of the respiratory epithelium. It is one of the etiologic agents of non-viral primary atypical pneumonia in man.Chlamydiaceae: A family of gram-negative, coccoid microorganisms, in the order CHLAMYDIALES, pathogenic for vertebrates. Genera include CHLAMYDIA and CHLAMYDOPHILA.Pneumonia, Mycoplasma: Interstitial pneumonia caused by extensive infection of the lungs (LUNG) and BRONCHI, particularly the lower lobes of the lungs, by MYCOPLASMA PNEUMONIAE in humans. In SHEEP, it is caused by MYCOPLASMA OVIPNEUMONIAE. In CATTLE, it may be caused by MYCOPLASMA DISPAR.Chlamydophila psittaci: A genus of CHLAMYDOPHILA infecting primarily birds. It contains eight known serovars, some of which infect more than one type of host, including humans.Chlamydiales: An order of obligately intracellular, gram-negative bacteria that have the chlamydia-like developmental cycle of replication. This is a two-stage cycle that includes a metabolically inactive infectious form, and a vegetative form that replicates by binary fission. Members of Chlamydiales are disseminated by aerosol or by contact. There are at least six recognized families: CHLAMYDIACEAE, Criblamydiaceae, Parachlamydiaceae, Rhabdochlamydia, Simkaniaceae, and Waddliaceae.Boidae: A family of snakes comprising the boas, anacondas, and pythons. They occupy a variety of habitats through the tropics and subtropics and are arboreal, aquatic or fossorial (burrowing). Some are oviparous, others ovoviviparous. Contrary to popular opinion, they do not crush the bones of their victims: their coils exert enough pressure to stop a prey's breathing, thus suffocating it. There are five subfamilies: Boinae, Bolyerinae, Erycinae, Pythoninae, and Tropidophiinae. (Goin, Goin, and Zug, Introduction to Herpetology, 3d ed, p315-320)Pneumonia, Bacterial: Inflammation of the lung parenchyma that is caused by bacterial infections.Psittacosis: Infection with CHLAMYDOPHILA PSITTACI (formerly Chlamydia psittaci), transmitted to humans by inhalation of dust-borne contaminated nasal secretions or excreta of infected BIRDS. This infection results in a febrile illness characterized by PNEUMONITIS and systemic manifestations.Klebsiella pneumoniae: Gram-negative, non-motile, capsulated, gas-producing rods found widely in nature and associated with urinary and respiratory infections in humans.Streptococcus pneumoniae: A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Respiratory Tract Infections: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.Community-Acquired Infections: Any infection acquired in the community, that is, contrasted with those acquired in a health care facility (CROSS INFECTION). An infection would be classified as community-acquired if the patient had not recently been in a health care facility or been in contact with someone who had been recently in a health care facility.Bacterial Proteins: Proteins found in any species of bacterium.Abortion, Veterinary: Premature expulsion of the FETUS in animals.Microviridae: A large family of lytic bacteriophages infecting enterobacteria; SPIROPLASMA; BDELLOVIBRIO; and CHLAMYDIA. It contains four genera: MICROVIRUS; Spiromicrovirus; Bdellomicrovirus; and Chlamydiamicrovirus.Chlamydiaceae Infections: Infections with bacteria of the family CHLAMYDIACEAE.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Bird Diseases: Diseases of birds not considered poultry, therefore usually found in zoos, parks, and the wild. The concept is differentiated from POULTRY DISEASES which is for birds raised as a source of meat or eggs for human consumption, and usually found in barnyards, hatcheries, etc.Acute Disease: Disease having a short and relatively severe course.Klebsiella Infections: Infections with bacteria of the genus KLEBSIELLA.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Pneumococcal Infections: Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.Chlamydia Infections: Infections with bacteria of the genus CHLAMYDIA.Sheep Diseases: Diseases of domestic and mountain sheep of the genus Ovis.Chlamydia: A genus of the family CHLAMYDIACEAE whose species cause a variety of diseases in vertebrates including humans, mice, and swine. Chlamydia species are gram-negative and produce glycogen. The type species is CHLAMYDIA TRACHOMATIS.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Aborted Fetus: A mammalian fetus expelled by INDUCED ABORTION or SPONTANEOUS ABORTION.Cat Diseases: Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.Parrots: BIRDS of the large family Psittacidae, widely distributed in tropical regions and having a distinctive stout, curved hooked bill. The family includes LOVEBIRDS; AMAZON PARROTS; conures; PARAKEETS; and many other kinds of parrots.

Infection of human endothelial cells with Chlamydia pneumoniae stimulates transendothelial migration of neutrophils and monocytes. (1/1035)

We have previously shown that different isolates of Chlamydia pneumoniae display heterogeneity in the in vitro stimulation of chemokines and adhesion molecules from infected human endothelial cells. In the present study, we examined the ability of different isolates of C. pneumoniae to promote transendothelial migration of neutrophils and monocytes. Human umbilical vein endothelial cells (HUVEC) were infected with low (<15)-passage C. pneumoniae isolates A-03, PS-32, and BR-393 and high (>40)-passage isolates BAL-16, TW-183, and T-2634, and levels of neutrophil and monocyte transendothelial migration were determined following 24 h of infection. Compared to mock-infected controls, significant increases in neutrophil migration were observed in response to most C. pneumoniae isolates examined (P < 0.001). Levels of monocyte migration were significantly increased in response to TW-183 and T-2634 (P < 0.001). Serial passage (>40 times) of the three low-passage isolates in HEp-2 cell cultures prior to infection of HUVEC generally resulted in the promotion of higher levels of neutrophil and monocyte transendothelial migration. These findings were compatible with differences observed in the extent of interleukin-8 (IL-8) and monocyte chemotactic protein-1 (MCP-1) stimulation between low- and high-passage A-03, PS-32, and BR-393. As opposed to C. pneumoniae, infection with C. trachomatis L2 caused only a slight increase in neutrophil transendothelial migration, which correlated with the lack of measurable IL-8 levels by this species. However, significant levels of monocyte migration were induced in response to C. trachomatis L2 despite a lack of measurable MCP-1 stimulation. C. trachomatis serovars A and E also failed to induce IL-8 and MCP-1 production in HUVEC. Results from this study indicate that the passage history of C. pneumoniae may play a role in the divergence of stimulatory activities observed among isolates in human endothelial cells. In addition, the differences observed between this organism and C. trachomatis suggest that the upregulation of IL-8 and MCP-1 in endothelial cells may be unique to C. pneumoniae.  (+info)

Chlamydia pneumoniae infection in human monocytes. (2/1035)

Chlamydia pneumoniae infection has been associated with cardiovascular diseases in seroepidemiological studies and by demonstration of the pathogen in atherosclerotic lesions. It has the capacity to infect several cell types, including monocyte-derived macrophages, which play an essential role in the development of atherosclerosis. However, the persistence of C. pneumoniae in mononuclear cells is poorly understood. To study the morphology and biological characteristics of the infection, human peripheral blood monocytes were infected with C. pneumoniae. Freshly isolated monocytes resisted the development of infectious progeny, and confocal and transmission electron microscopy showed that the morphology of the inclusions and chlamydial particles was abnormal. Addition of tryptophan or antibodies against gamma interferon did not diminish the inhibition of C. pneumoniae, suggesting that other factors are involved in the chlamydiostatic activity of the monocytes. Chlamydial mRNA was expressed at least 3 days after infection, however, and a capability for infected monocytes to induce a positive lymphocyte proliferative response was detected for up to 7 days, indicating that C. pneumoniae remains metabolically active in the monocytes in vitro. These results are in accordance with the hypothesis that C. pneumoniae may participate in the maintenance of local immunological response and inflammation via infected monocytes and thus enhance atherosclerosis.  (+info)

Chlamydia pneumoniae and atherosclerosis. (3/1035)

OBJECTIVE: To review the literature for evidence that chronic infection with Chlamydia pneumoniae is associated with atherosclerosis and acute coronary syndromes. DATA SOURCES: MEDLINE and Institute of Science and Information bibliographic databases were searched at the end of September 1998. Indexing terms used were chlamydi*, heart, coronary, and atherosclerosis. Serological and pathological studies published as papers in any language since 1988 or abstracts since 1997 were selected. DATA EXTRACTION: It was assumed that chronic C pneumoniae infection is characterised by the presence of both specific IgG and IgA, and serological studies were examined for associations that fulfilled these criteria. Pathological studies were also reviewed for evidence that the presence of C pneumoniae in diseased vessels is associated with the severity and extent of atherosclerosis. DATA SYNTHESIS: The majority of serological studies have shown an association between C pneumoniae and atherosclerosis. However, the number of cases in studies that have reported a positive association when using strict criteria for chronic infection is similar to the number of cases in studies which found no association. Nevertheless, the organism is widely found in atherosclerotic vessels, although it may not be at all diseased sites and is not confined to the most severe lesions. Rabbit models and preliminary antibiotic trials suggest that the organism might exacerbate atherosclerosis. CONCLUSION: More evidence is required before C pneumoniae can be accepted as playing a role in atherosclerosis. Although use of antibiotics in routine practice is not justified, large scale trials in progress will help to elucidate the role of C pneumoniae.  (+info)

Chlamydia pneumoniae antibodies are associated with an atherogenic lipid profile. (4/1035)

OBJECTIVE: To determine, within a representative population group of men and women, whether alteration of the lipid profile might underlie the reported association between Chlamydia pneumoniae and ischaemic heart disease. DESIGN AND SETTING: Cross sectional survey in an area with a high incidence of ischaemic heart disease. SUBJECTS: 400 randomly selected participants in the World Health Organisation MONICA project's third population survey in Northern Ireland. MAIN OUTCOME MEASURES: Stored sera were examined by microimmunofluorescence for IgG antibodies to C pneumoniae at a dilution of 1 in 64. Mean total and high density lipoprotein (HDL) cholesterol were compared between seropositive and seronegative individuals with adjustment for age, measures of socioeconomic status, smoking habit, alcohol consumption, body mass index, and the season during which blood had been taken. RESULTS: In seropositive men, adjusted mean serum total cholesterol and HDL cholesterol were 0.5 mmol/l (9.2%) higher and 0.11 mmol/l (9.3%) lower, respectively, than in seronegative men. Differences in women did not achieve statistical significance, but both total cholesterol and HDL cholesterol were higher (3.6% and 5.8%, respectively) in seropositive than in seronegative individuals. CONCLUSIONS: There is serological evidence that C pneumoniae infection is associated with an atherogenic lipid profile in men. Altered lipid levels may underlie the association between C pneumoniae and ischaemic heart disease.  (+info)

Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease. (5/1035)

OBJECTIVE: To study possible associations between coronary heart disease and serological evidence of persistent infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus. DESIGN: Population based, case-control study, nested within a randomised trial. SETTING: Five general practices in Bedfordshire, UK. INDIVIDUALS: 288 patients with incident or prevalent coronary heart disease and 704 age and sex matched controls. RESULTS: High concentrations of serum IgG antibodies to H pylori were present in 54% of cases v 46% of controls, with corresponding results for C pneumoniae seropositivity (33% v 33%), and cytomegalovirus seropositivity (40% v 31%). After adjustments for age, sex, smoking, indicators of socioeconomic status, and standard risk factors, the odds ratios (95% confidence intervals) for coronary heart disease of seropositivity to these agents were: 1.28 (0.93 to 1.75) for H pylori, 0.95 (0.66 to 1.36) for C pneumoniae, and 1.40 (0.96 to 2. 05) for cytomegalovirus. CONCLUSIONS: There is no good evidence of strong associations between coronary heart disease and serological markers of persistent infection with H pylori, C pneumoniae, or cytomegalovirus. To determine the existence of moderate associations between these agents and disease, however, larger scale studies will be needed that can keep residual confounders to a minimum.  (+info)

Elevated levels of C-reactive protein at discharge in patients with unstable angina predict recurrent instability. (6/1035)

BACKGROUND: In a group of patients admitted for unstable angina, we investigated whether C-reactive protein (CRP) plasma levels remain elevated at discharge and whether persistent elevation is associated with recurrence of instability. METHODS AND RESULTS: We measured plasma levels of CRP, serum amyloid A protein (SAA), fibrinogen, total cholesterol, and Helicobacter pylori and Chlamydia pneumoniae antibody titers in 53 patients admitted to our coronary care unit for Braunwald class IIIB unstable angina. Blood samples were taken on admission, at discharge, and after 3 months. Patients were followed for 1 year. At discharge, CRP was elevated (>3 mg/L) in 49% of patients; of these, 42% had elevated levels on admission and at 3 months. Only 15% of patients with discharge levels of CRP <3 mg/L but 69% of those with elevated CRP (P<0.001) were readmitted because of recurrence of instability or new myocardial infarction. New phases of instability occurred in 13% of patients in the lower tertile of CRP (/=8.7 mg/L, P<0.001). The prognostic value of SAA was similar to that of CRP; that of fibrinogen was not significant. Chlamydia pneumoniae but not Helicobacter pylori antibody titers significantly correlated with CRP plasma levels. CONCLUSIONS: In unstable angina, CRP may remain elevated for at >/=3 months after the waning of symptoms and is associated with recurrent instability. Elevation of acute-phase reactants in unstable angina could represent a hallmark of subclinical persistent instability or of susceptibility to recurrent instability and, at least in some patients, could be related to chronic Chlamydia pneumoniae infection.  (+info)

Detection of Chlamydia pneumoniae but not cytomegalovirus in occluded saphenous vein coronary artery bypass grafts. (7/1035)

BACKGROUND: A causal relation between atherosclerosis and chronic infection with Chlamydia pneumoniae and/or cytomegalovirus (CMV) has been suggested. Whether the unresolved problem of venous coronary artery bypass graft occlusion is related to infection with C pneumoniae and/or CMV has not been addressed. METHODS AND RESUTLS: Thirty-eight occluded coronary artery vein grafts and 20 native saphenous veins were examined. Detection of C pneumoniae DNA was performed by use of nested polymerase chain reaction (PCR). Homogenisates from the specimen were cultured for identification of viable C pneumoniae. Both conventional PCR and quantitative PCR for detection of CMV DNA were applied. Differential pathological changes (degree of inflammation, smooth muscle cell proliferation [MIB-1]) were determined and correlated to the detection of both microorganisms. C pneumoniae DNA could be detected in 25% of occluded vein grafts. Viable C pneumoniae was recovered from 16% of occluded vein grafts. Except for 1 native saphenous vein, all control vessels were negative for both C pneumoniae detection and culture. All pathological and control specimens were negative for CMV DNA detection. Pathological changes did not correlate with C pneumoniae detection. CONCLUSIONS: Occluded aorto-coronary venous grafts harbor C pneumoniae but not CMV. The detection of C pneumoniae in occluded vein grafts warrants further investigation.  (+info)

Single channel analysis of recombinant major outer membrane protein porins from Chlamydia psittaci and Chlamydia pneumoniae. (8/1035)

We recently demonstrated that the major outer membrane protein of Chlamydia psittaci, the primary vaccine candidate for combating chlamydial infections, functions as a porin-like ion channel. In this study, we have cloned, expressed and functionally reconstituted recombinant major outer membrane proteins from C. psittaci and Chlamydia pneumoniae and analysed them at the single channel level. Both form porin-like ion channels that are functionally similar to those formed by native C. psittaci major outer membrane protein. Also, like the native channels, recombinant C. psittaci channels are modified by a native major outer membrane protein-specific monoclonal antibody. This is the first time that native function has been demonstrated for recombinant chlamydial major outer membrane proteins. Future bilayer reconstitution will provide a strategy for detailed structure/function studies of this new subclass of bacterial porins and the work also has important implications for successful protein refolding and the development of improved subunit vaccines.  (+info)

*Chlamydophila pneumoniae

... is a species of Chlamydophila, an obligate intracellular bacterium that infects humans and is a major ... Medicine portal Chlamydia Pneumoniae cpnhelp.org Type strain of Chlamydophila pneumoniae at BacDive - the Bacterial Diversity ... Chlamydophila pneumoniae is a small gram negative bacterium (0.2 to 1 μm) that undergoes several transformations during its ... Chlamydophila pneumoniae at the US National Library of Medicine Medical Subject Headings (MeSH) Mayer G (24 June 2010). " ...

*Chlamydiae

1989 [Chlamydophila pneumoniae (Grayston et al. 1989) Everett, Bush & Andersen 1999] Genus Chlamydophila Everett, Bush & ... which causes the eye-disease trachoma and the sexually transmitted infection chlamydia Chlamydophila pneumoniae, which causes a ... The genera have been recently united where species belonging to the Chlamydophila genus have been reclassified as Chlamydia ... However, CSIs and CSPs have been found specifically for Chlamydophila species, supporting their distinctness from Chlamydia, ...

*Coronary artery disease

A more controversial link is that between Chlamydophila pneumoniae infection and atherosclerosis. While this intracellular ... "Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study". Annals of ... "Infection with Chlamydia pneumoniae as a cause of coronary heart disease: the hypothesis is still untested". Pathogens and ...

*UbiD protein domain

Liu J, Liu JH (2006). "Ubiquinone (coenzyme Q) biosynthesis in Chlamydophila pneumoniae AR39: identification of the ubiD gene ...

*Carcinogenic bacteria

Kocazeybek B (August 2003). "Chronic Chlamydophila pneumoniae infection in lung cancer, a risk factor: a case-control study". J ...

*Rifabutin

It has also found to be useful in the treatment of Chlamydophila pneumoniae (Cpn) infection. Scientists at the Italian drug ...

*Bacterial pneumonia

Atypical bacteria causing pneumonia are Coxiella burnetii, Chlamydophila pneumoniae (J16.0), Mycoplasma pneumoniae (J15.7), and ... ciprofloxacin Moraxella catarrhalis Chlamydophila pneumoniae - doxycycline Chlamydophila psittaci - erythromycin Mycoplasma ... Streptococcus pneumoniae is a Gram-positive bacterium that often lives in the throat of people who do not have pneumonia. Other ... Streptococcus pneumoniae - amoxicillin (or erythromycin in patients allergic to penicillin); cefuroxime and erythromycin in ...

*Acute bronchitis

Bacteria are uncommon pathogens but may include Mycoplasma pneumoniae, Chlamydophila pneumoniae, Bordetella pertussis, ... A small number of cases are due to high levels of air pollution or bacteria such as Mycoplasma pneumoniae or Bordetella ... Streptococcus pneumoniae, and Haemophilus influenzae.[citation needed] Damage caused by irritation of the airways leads to ...

*Asthma-related microbes

Chlamydophila pneumoniae, formerly known as Chlamydia pneumoniae, is a bacterium that belongs to the phylum Chlamydiae, order ... Similarly, M. pneumoniae infection promotes a T helper type 2 response, which is why M pneumoniae-positive patients with asthma ... Larsen, R., Pogliano, K. "Chlamydophila pneumoniae". Microbe Wiki. Retrieved 24 October 2012. Beatty, WL; Morrison, RP.; Byrne ... Thus, Chlamydia pneumoniae, Mycoplasma pneumoniae and human rhinoviruses are microbes that play a major role in non-atopic ...

*Atypical pneumonia

Chlamydophila pneumoniae Mild form of pneumonia with relatively mild symptoms. Chlamydophila psittaci Causes psittacosis. ... Mycoplasma pneumoniae Usually occurs in younger age groups and may be associated with neurological and systemic (e.g. rashes) ... At the time that atypical pneumonia was first described, organisms like Mycoplasma, Chlamydophila, and Legionella were not yet ... Robbins and Cotran Pathologic Basis of Disease, 8th edition, Kumar et al., Philadelphia, 2010, p. 714 MYCOPLASMA PNEUMONIAE at ...

*Pneumonia

Chlamydophila pneumoniae in 13%, and Mycoplasma pneumoniae in 3% of cases; Staphylococcus aureus; Moraxella catarrhalis; ... Initial work identifying the two common bacterial causes, Streptococcus pneumoniae and Klebsiella pneumoniae, was performed by ... The organisms most commonly involved are Streptococcus pneumoniae, Haemophilus influenzae, and Klebsiella pneumoniae. Other ... Streptococcus pneumoniae is more common in the winter, and should be suspected in persons aspirating a large amount of ...

*Myocardial infarction

A number of acute and chronic infections including Chlamydophila pneumoniae, influenza, Helicobacter pylori, and Porphyromonas ...

*Pharyngitis

Chlamydophila pneumoniae, and Mycoplasma pneumoniae. Streptococcal pharyngitis Streptococcal pharyngitis or strep throat is ... The most common is Group A streptococcus, but others include Streptococcus pneumoniae, Haemophilus influenzae, Bordetella ...

*Atherosclerosis

Chlamydophila pneumoniae, though trials of current antibiotic treatments known to be usually effective in suppressing growth or ...

*Chlamydia (genus)

Chlamydophila psittaci, Chlamydophila pneumoniae, and Chlamydophila pecorum. Because of Chlamydia's unique developmental cycle ... The elementary body may be 0.25 to 0.30 μm in diameter, and it mainly consists of C. trachomatis, C. pneumoniae, and C. ... About 80% of the genes in C. trachomatis and C. pneumoniae are orthologs. Adapted after Read et al. 2000 Chlamydia may be found ... "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39". Nucleic Acids Research. 28 (6): 1397-1406. doi: ...

*Parachlamydia acanthamoebae

... such as Chlamydia trachomatis or Chlamydophila pneumoniae. Amann, Rudolf; Springer, Nina; Schönhuber, Wilhelm; Ludwig, Wolfgang ...

*Multiple sclerosis drug pipeline

Anecdotal reports of the use of antimicrobial agents against Chlamydophila pneumoniae are favorable, but only one double-blind ... MS patients are more likely to have detectable levels of Chlamydophila pneumoniae DNA in their cerebrospinal fluid, compared to ... though there is only preliminary evidence waiting to be confirmed Antimicrobial agents against Chlamydophila pneumoniae: ... Bagos PG, Nikolopoulos G, Ioannidis A (2006). "Chlamydia pneumoniae infection and the risk of multiple sclerosis: a meta- ...

*List of clinically important bacteria

... fetus Campylobacter jejuni Campylobacter pylori Chlamydia Chlamydia trachomatis Chlamydophila Chlamydophila pneumoniae ( ... previously called Chlamydia pneumoniae) Chlamydophila psittaci (previously called Chlamydia psittaci) Clostridium Clostridium ... Mycoplasma Mycoplasma fermentans Mycoplasma genitalium Mycoplasma hominis Mycoplasma penetrans Mycoplasma pneumoniae Neisseria ... influenzae Haemophilus parainfluenzae Haemophilus pertussis Haemophilus vaginalis Helicobacter pylori Klebsiella pneumoniae ...

*Lower respiratory tract infection

Legionella pneumophila Mycoplasma pneumoniae Chlamydophila pneumoniae Chlamydia psittaci Parasitic infections: Respiratory ... This total only accounts for Streptococcus pneumoniae and Haemophilus Influenzae infections and does not account for atypical ... The most common cause of pneumonia is pneumococcal bacteria, Streptococcus pneumoniae accounts for 2/3 of bacteremic pneumonias ... 50% of patients are colonised with Haemophilus influenzae, Streptococcus pneumoniae or Moraxella catarrhalis. Antibiotics have ...

*Levofloxacin

Chlamydophila pneumoniae and Mycoplasma pneumoniae). Compared to earlier antibiotics of the fluoroquinoline class such as ... Due to its widespread use, common pathogens such as Escherichia coli and Klebsiella pneumoniae have developed resistance. In ... Lafredo SC, Foleno BD, Fu KP (1993). "Induction of resistance of Streptococcus pneumoniae to quinolones in vitro". Chemotherapy ... The drug exhibits enhanced activity against the important respiratory pathogen Streptococcus pneumoniae relative to earlier ...

*List of MeSH codes (B03)

Chlamydophila MeSH B03.440.190.190.230.249 --- Chlamydophila pneumoniae MeSH B03.440.190.190.230.500 --- Chlamydophila psittaci ... Klebsiella pneumoniae MeSH B03.440.450.425.435 --- Kluyvera MeSH B03.440.450.425.500 --- Morganella MeSH B03.440.450.425. ... Mycoplasma pneumoniae MeSH B03.440.560.580.553.553.670 --- Mycoplasma pulmonis MeSH B03.440.560.580.553.553.720 --- Mycoplasma ... Klebsiella pneumoniae MeSH B03.660.250.150.410 --- Kluyvera MeSH B03.660.250.150.500 --- Morganella MeSH B03.660.250.150. ...

*List of human flora

Chlamydia trachomatis Hemophilus influenzae Staphylococcus aureus Staphylococcus epidermidis Chlamydophila pneumoniae ...

*Community-acquired pneumonia

In contrast, older children and teenagers are more likely to acquire Mycoplasma pneumoniae and Chlamydophila pneumoniae than ... children under five are much less likely to have pneumonia caused by Mycoplasma pneumoniae, Chlamydophila pneumoniae or ... infections by atypical bacteria such as Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Legionella pneumophila can also ... with common bacterial causes including Streptococcus pneumoniae, Escherichia coli, Klebsiella pneumoniae, Moraxella catarrhalis ...

*Chlamydiaceae

Six species belong to Chlamydophila: C. pneumoniae (often also called Chlamydia pneumoniae), C. pecorum, C. psittaci, C. ... Chlamydophila species do not produce detectable glycogen and have one ribosomal operon. These species are naturally found ... The Chlamydiaceae family currently includes two genera and one candidate genus: Chlamydia, Chlamydophila, and candidatus ...

*Chlamydophila

... pneumoniae Chlamydophila pecorum Chlamydophila felis Chlamydophila psittaci Chlamydophila abortus Chlamydophila ... Chlamydophila was recognized in 1999, with six species in Chlamydophila and three in the original genus, Chlamydia. All ... "Chlamydophila". List of Prokaryotic names with Standing in Nomenclature. Retrieved 2011-06-11. Chlamydophila at the US National ... Divergence of Chlamydophila from Chlamydia is indicated by sequence similarity clustering of protein coding and ribosomal RNA ...

*Chlamydia (disambiguation)

... a chlamydial species found in cats Chlamydophila pecorum, a chlamydial species common in livestock Chlamydophila pneumoniae, ... Chlamydophila, another genus of pathogenic bacteria Chlamydophila abortus, a chlamydial species that causes abortion in mammals ... Chlamydophila caviae, a chlamydial species found in Guinea pigs Chlamydophila felis, ... also known as Chlamydia pneumoniae, an airborne chlamydial species responsible for human respiratory infection and numerous ...
Chlamydophila pneumoniae ATCC ® 53592D™ Designation: DNA from Chlamydophila pneumoniae strain AR-39 (ATCC ® 53592™) Application: It is suitable for use in PCR and other molecular bacteriology and virology applications.
One hundred eight children with a history of asthma-related symptoms were followed longitudinally for 13 months. Subjects kept a daily diary of symptoms and peak flow rates, and when asthma-related symptoms occurred an investigator was contacted for collection of nasal aspirates. A total of 292 samples were collected during symptomatic episodes and a total of 65 children provided a sample when asymptomatic. Polymerase chain reaction (PCR) was used to identify the presence of C pneumoniae and M pneumoniae. The presence of secretory immunoglobulin A (IgA) specific to C pneumoniae was also detected. ...
Chlamydophila (Formerly Chlamydia) Pneumoniae Infection answers are found in the 5-Minute Pediatric Consult powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2910-3. Related Articles, Links Chronic Chlamydia pneumoniae infection is associated with a serum lipid profile known to be a risk factor for atherosclerosis.. Laurila A, Bloigu A, Nayha S, Hassi J, Leinonen M, Saikku P.. National Public Health Institute, Oulu, Finland.. Chlamydia pneumoniae infection has been associated with coronary heart disease. To evaluate the mechanisms of this association, we studied whether chronic C. pneumoniae infection affects serum lipid values similarly to acute infections. Triglyceride, total and HDL cholesterol concentrations, and C. pneumoniae antibodies were measured from paired serum samples of 415 Finnish males taken 3 years apart. Chronic infection, defined as persistent IgG and IgA antibodies, was found in 20%, and the antibodies were negative (IgG , 32 and IgA , 16 in both samples) in 15% of the cases studied. The serum triglyceride and total cholesterol concentrations were higher in the subjects with a chronic ...
Definition : Molecular assay reagents intended to identify Chlamydophila pneumoniae, a bacterium of the family Chlamydiaceae, by detecting specific genetic information of the ribosomal ribonucleic acid (rRNA) of the target bacteria. These bacteria may cause respiratory infections and mild atypical pneumonia.. Entry Terms : "Chlamydophila pneumoniae Detection/Identification Reagents" , "Chlamydophila Species Detection/Identification Reagents" , "Reagents, Molecular Assay, Infection, Bacteria, Chlamydophila pneumoniae, RRNA". UMDC code : 21528 ...
In the present study, the relationship between airway inflammation and infection with C. pneumoniae in acute asthma was examined. It was found that over one-third of adults presenting with acute severe asthma showed a rise in C. pneumoniae-specific antibodies consistent with acute infection, reinfection or reactivation of latent infection with C. pneumoniae. These subjects exhibited a more intense inflammatory response during the acute exacerbation, with an increase in sputum TCC, neutrophil count and ECP level compared to subjects with acute asthma who did not show an increase in C. pneumoniae antibody levels.. Subjects were recruited from patients presenting to the emergency department with acute asthma, who had at least moderate airflow obstruction, representing a group with more severe acute asthma. This group was selected for study based on previous work linking C. pneumoniae infection with asthma exacerbations and severe asthma 6, 7, 14. The sputum induction time tended to be shorter at ...
Respiratory infections precipitate wheezing in many asthmatic patients and may be involved in the aetiopathogenesis of asthma. Several studies have demonstrated that viral infections may provoke asthma. Bacterial infections seem to play a minor role. However, Chlamydia pneumoniae has been recently reported as a possible cause of asthma. The aim of the present study was to evaluate the role of C. pneumoniae infection in acute exacerbations of asthma in adults. Seventy four adult out-patients with a diagnosis of acute exacerbation of asthma were studied. Acute and convalescent (, or = 3 weeks) serological determination of antibodies to cytomegalovirus, respiratory syncytial virus, adenovirus, influenza A and B, parainfluenza 1 and 3, Mycoplasma pneumoniae and Legionella pneumophila were performed by means of immunofluorescence tests. C. pneumoniae specific antibodies were detected by two microimmunofluorescence tests using a specific antigen (TW-183) and a kit with three chlamydial antigens. ...
Chlamydia pneumoniae is an etiological agent of human respiratory disease, causing 5-10% of pneumoniae bronchitis and sinusitis. This pathogen has also been ass...
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A feature of this study was the careful control of PCR inhibition. DNA extracts of coronary arteries caused significant levels of PCR inhibition, associated particularly with severe atherosclerosis. Lipid and particularly calcium were the main sources of inhibition, illustrating the importance of using PCR inhibition controls when studying atheroma lesions of differing severity. A similar use of λ DNA for this purpose was recently reported by another group.15 Inhibition was eliminated in all but 1 case by 10-fold dilution, but this was associated with a reduction in chlamydial detection from 39% to 29%. As reported by others,4 16 repeated testing of samples by PCR did not always produce consistent results. We attribute this to the low amounts of C pneumoniae DNA present in coronary arteries, to the sampling errors arising from use of small sample volumes, and to PCR inhibition. Our strategy of testing all samples in triplicate should have reduced any resulting underestimation of the prevalence ...
BioAssay record AID 93884 submitted by ChEMBL: Minimum inhibitory concentration of compound for its inhibitory activity against Klebsiella pneumoniae growth at 2.4 ug/mL.
Objective: To investigate the association between Chlamydia pneumoniae and matrix metalloproteinase-9 (MMP-9) in atherosclerotic plaques.. Design: 31 coronary atherosclerotic plaque specimens were studied by immunohistochemistry, polymerase chain reaction (PCR), and reverse transcription PCR for the presence of C pneumoniae antigen and genomic DNA, and of MMP-9 protein and transcripts.. Results: Immunohistochemical analysis identified a strong association between the presence of C pneumoniae antigen and production of MMP-9 in coronary atherosclerotic plaques (p = 0.001). Furthermore, analysis of the intralesional amount of C pneumoniae and MMP-9 indicated an increased number of cells positive for MMP-9 in arterial sections that had increased C pneumoniae positivity (p , 0.05).. Conclusions: This study provides evidence of an association between expression of MMP-9 and the intravascular presence of C pneumoniae and may suggest a potential pathological mechanism whereby C pneumoniae may contribute ...
Chlamydia pneumoniae is a ubiquitous intracellular pathogen, first associated with human respiratory disease and subsequently detected in a range of mammals, amphibians, and reptiles. Here we report the draft genome sequence for strain B21 of C. pneumoniae, isolated from the endangered Australian marsupial the western barred bandicoot.; ;
Chronic infections may predispose to malignant growth. Recently, serological markers of chronic Chlamydia pneumoniae infection have been associated with lung cancer. Our aim was to study the possible association between chronic chlamydial infections and malignant lymphomas. The present case-control study involved 72 patients with lymphoma 31...
The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011 ...
The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011 ...
Enzyme immunoassay for the detection of IgG antibodies against Chlamydophila pneumoniae in human serum or plasma. SmartEIA kit is specifically designed for automated analysis using the Agility instrument.
In the present study, we showed that the presence of an elevated level of IgA antibodies against human Hsp60 protein predicts a coronary event several years before the coronary event actually occurs. Researchers at Wicks laboratory have studied the role of microbial Hsp60 in the development of atherosclerosis. Their studies indicate that immunization with mycobacterial Hsp65 induces atherosclerosis in laboratory animals.3,4⇓ In humans, they have found that immunity to mycobacterial Hsp65 is associated with the pathogenesis of carotid5 and coronary6 atherosclerosis. Hsp65 antibodies were found more often in patients with atherosclerotic lesions than in persons without such lesions,5 and the presence of these antibodies also predicted carotid atherosclerosis.7,8⇓ It has been shown that these antibodies cross-react with E coli Hsp60, chlamydial Hsp60, and human Hsp60 antibodies and are cytotoxic to endothelial cells.9 In the present study, we confirmed these findings and extended them to apply ...
BACKGROUND:. Recent studies have associated evidence of Chlamydia pneumoniae infection with coronary and carotid atherosclerosis and evidence of increased infection with cytomegalovirus (CMV) in patients developing restenosis or with atherosclerosis. Several other common pathogens have been less consistently associated with atherosclerosis. Altered parameters of inflammation and hemostasis have been identified as prognostic factors of myocardial infarction and have been linked as possible pathogenetic mechanisms. Recent studies have indicated that peripheral blood mononuclear cells (PBMC) from patients with coronary artery disease frequently include Chlamydia pneumoniae DNA and stimulation of PBMCs can reflect an unsuccessful host cellular immune response to CMV associated with elevated C-reactive protein (CRP).. DESIGN NARRATIVE:. The study has both a nested case-control design and a nested cohort design within the Strong Heart Study (SHS), an ongoing cohort study of 4,549 American Indians. The ...
The microimmunofluorescence technique (MIF) is recognized as the only test hitherto allowing discrimination between different Chlamydia species and is considered to be the reference method for serology. This method was developed for the detection of IgG and IgM antibodies only. We investigated the effects of some test parameters on the ability of MIF to detect Chlamydia pneumoniae IgA. These parameters were the time needed for binding of serum IgA to C. pneumoniae antigen and the effect of antigen concentration on the outcome of IgA antibody testing. It was found that the most sensitive MIF tests for the detection of serum IgA antibodies were those in which an overnight incubation of sera with antigen slides containing high concentrations of chlamydial elementary bodies was employed. The number of patients with chronic infections found to have elevated IgA titers was increased by 25% using longer incubation times for the antibody-antigen reaction. Thirty-two sera from patients with coronary ...
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Chlamydia pneumoniae or C. pneumoniae is a common respiratory pathogen, and almost all people are infected by the age of 20 and causes up to 10% of community-acquired pneumonia cases. It has been associated with acute respiratory diseases, pneumon
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Im new to the forum (but not new to chronic illness...). Ive been unwell for just over 20 years with ME/CFSi. In that time Ive explored various causes for my symptoms and tried the usual gamut of treatments, at least those that seemed rational at the time. In recent years Ive become hypersensitive to medications and supplementsi, so Ive slowed down my turnover of treatments as many times I cant tolerate them.. Several years ago my doctor ran a panel of PCRi tests and the only one that came back positive was Cpni. I then did a treatment with Sulfoxime and Dioxychor infusions x 3 and retested twice. The test reported negative both times, but I remained unwell. From what I understand so far, it may be possible for there to be reservoirs of infection in deep tissue meaning a peripheral blood PCR may represent a false negative?. Last year I decided to investigate for Cpn again and we did the Infectolab Chlamydia pneumoniae Elispot lymphocyte transformation test. The lab result was +14 (ref ,2) ...
Abcam provides specific protocols for Anti-Mycoplasma pneumoniae antibody (HRP) (ab20352) : Western blot protocols, Immunocytochemistry &…
Blocks bacterial protein synthesis at the level of the 50S ribosomal subunit. Therapeutic Effects: Resolution of infection. Spectrum: Active against the following organisms: Staphylococcus aureus (methicillin and erythromycin-susceptible strains only), Streptococcus pneumoniae (including multidrug-resistant strains), Haemophilus influenzae, Moraxella catarrhalis, Chlamydophila pneumoniae, and Mycoplasma pneumoniae. ...
Effect of therapy with antibiotics on lipid metabolism and antioxidant reserve of patients with ischemic heart disease during Chlamydia pneumoniae infection. - Klochkov VA, Dovgalevskiĭ PIa, Umetskiĭ KS, Chalyk NE, Ansimova OM, Zigangirova NA, Petiaev I. (2005) Kardiologiia, 45(12):58-61 ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
宮下 修行 , 松本 明 , 副島 林造 , 岸本 寿男 , 中島 正光 , 二木 芳人 , 松島 敏春 日本化学療法学会雜誌 = Japanese journal of chemotherapy 45(5), 256-264, 1997-05-25 参考文献44件 被引用文献1件 ...
TY - JOUR. T1 - Chlamydia pneumoniae serology. T2 - Interlaboratory variation in microimmunofluorescence assay results. AU - Peeling, Rosanna W.. AU - Wang, San Pin. AU - Grayston, J. Thomas. AU - Blasi, Francesco. AU - Boman, Jens. AU - Clad, Andreas. AU - Freidank, Heike. AU - Gaydos, Charlotte A.. AU - Gnarpe, Judy. AU - Hagiwara, Toshikatsu. AU - Jones, Robert B.. AU - Orfila, Jeanne. AU - Persson, Kenneth. AU - Puolakkainen, Mirja. AU - Saikku, Pekka. AU - Schachter, Julius. PY - 2000. Y1 - 2000. N2 - The lack of standardization in chlamydia serology has made interpretation of published data difficult. This study was initiated to determine the extent of interlaboratory variation of microimmunofluorescence (MIF) test results for the serodiagnosis of Chlamydia pneumoniae infections. Identical panels of 22 sera were sent to 14 laboratories in eight countries for the determination of IgG and IgM antibodies by MIF. Although there was extensive variation in the numeric titer values, the overall ...
Background: Preeclampsia is one of the complexities of maternal and neonatal health. The relation between chronic Chlamydia pneumoniae and Cytomegalovirus infections with atherosclerosis has been shown previously.. Objective: To evaluate the role of rising titer of cytomegalovirus and Chlamydia pneumoniae IgG in pathogenesis and timing of onset of preeclampsia.. Methods: A case-control study carried out in the department of Obstetrics and Gynecology of Al-Yarmouk Teaching Hospital (Baghdad-Iraq) for one year from the 1st of October 2014 to the 30th of September 2015. The study included 120 pregnant women who were divided into: study group that subdivided into early onset preeclampsia (group I): included 30 singleton pregnant women presented with clinical onset of preeclampsia 28-33+6 weeks gestation and late onset preeclampsia (group II): included 30 singleton pregnant women presented with clinical onset of preeclampsia ≥ 34 weeks gestation. Other sixty healthy non complicated term pregnant ...
The Chlamydia pneumoniae/Atherosclerosis Study Group*. From the University of Louisville, Louisville, Kentucky. For the current author address, see end of text. *For members of the Chlamydia pneumoniae/Atherosclerosis Study Group, see the Appendix. Grant Support: By the Jewish Hospital Heart and Lung Institute, Louisville, Kentucky. Requests for Reprints: Julio A. Ramirez, MD, Division of Infectious Diseases, MDR Building, Room 622, 511 South Floyd Street, University of Louisville, Louisville, KY 40292 ...
1. Melnic JL, Hu C, Burek J i wsp. Cytomegalovirus DNA in arteria walls of patients with atherosclerosis. J Med Virol 1994; 42:170-4. 2. Kaplan M, Yavuz SS, Cinar J i wsp. Determinative of Chlamydia pneumoniae and Helicobacter pylori in atherosclerotic plaques of carotid artery by polymerase chain reaction. Int Infect Dis 2006; 10(2):116-23. 3. Espinola-Klein C, Rupprecht HJ, Blaukenburg S i wsp. Are morphological of function changes in the carotid artery wall associated with Chlamydia pneumoniae, Helicobacter pylori, Cytomegalovirus or Herpes simplex virus infection. Stroke 2008; 31:2127-33. 4. Farsak B, Yildirir A, Akyon Y i wsp. Detection of Chlamydia pneumoniae and Helicobacter pylori DNA in human atherosclerotic plaques by PCR. J Clin Microbiol 2000; 38(2):4408-11. 5. Kaklikkaya I, Kaklikaya N, Burak K i wsp. Investigation of Chlamydia pneumoniae DNA, chlamydial lipopolisaccharide antigens and Helicobacter pylori DNA in atherosclerotic plaque with aortoiliac occlusive disease. Cardiovasc ...
Naiki Y, Sorrentino R, Wong MH, Michelsen KS, Shimada K, Chen S, Yilmaz A, Slepenkin A, Schröder NW, Crother TR, Bulut Y, Doherty TM, Bradley M, Shaposhnik Z, Peterson EM, Tontonoz P, Shah PK, Arditi M. TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis. J Immunol. 2008 Nov 15;181(10):7176-7185 ...
The role of Chlamydia pneumoniae in the etiology of acute lower respiratory tract infections in infants and children is little understood. We studied the prevalence of C. pneumoniae infection in hospitalized infants and children with acute lower resp
Different serological methods are being used, and the different results may be related to the choice of method.Some investigators have used methods detecting the species-specific MOMP antibodies (4, 11, 14, 22, 23), and some have used methods detecting the genus-specific LPS antibodies (5, 11, 17, 22). The MIF technique has generally been regarded as a "gold standard" for the detection of C. pneumoniae antibodies in seroepidemiological studies. However, MIF methods differ from commercial methods to in-house MIF techniques, and the antigen composition varies between tests. In addition, some authors have focused on IgA positivity, some have focused on IgG, and some have used a combination of the two.. The use of several different methods would be no problem if the agreement between the tests is generally high. Our observations regarding the number of seropositives obtained by the different methods suggest that the sensitivity of the MIF method was higher than that of the Labsystems EIA, while the ...
article{5cc97b13-4eb4-4078-be58-2699d83a4b7b, author = {Liuba, Petru and Pesonen, Erkki and Paakkari, Ilari and Batra, Satish and Andersen, Leif and Forslid, Anders and Ylä-Herttuala, Seppo and Persson, Kenneth and Wadström, Torkel and Wang, Xin and Laurini, Ricardo}, issn = {1423-0135}, language = {eng}, number = {2}, pages = {115--122}, publisher = {Karger}, series = {Journal of Vascular Research1992-01-01+01:00}, title = {Co-Infection with CHLAMYDIA PNEUMONIAE and HELICOBACTER PYLORI Results in Vascular Endothelial Dysfunction and Enhanced VCAM-1 Expression in ApoE-Knockout Mice.}, url = {http://dx.doi.org/10.1159/000070708}, volume = {40}, year = {2003 ...
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Dilated cardiomyopathy (DCM), characterised by a severe dysfunction of the heart muscle, often results from a myocarditis, which could be caused by a variety of organisms or mediated by autoimmune responses to the exposure of cardiac specific antigen, such as myosin, after cardiomyocyte damage. DCM of humans can be experimentally reproduced in susceptible mouse strains by immunisation with purified cardiac myosin.1 Moreover, chlamydia infection may mediate heart disease through an antigenic mimicry between the chlamydia outer membrane protein and muscle specific α myosin of the heart.2 The aim of this study was to investigate the prevalence of Chlamydia pneumoniae infection by measuring the serum IgG and IgA antibodies against C pneumoniae in patients with DCM.. Twenty six consecutive patients with DCM, aged 56.9 (15.5) years, diagnosed according to the World Health Organization/International Society and Federation of Cardiology criteria,3 were enrolled. Twenty eight healthy subjects, mean (SD) ...
Lim, C., C.J. Hammond, S.T. Hingley and B.J. Balin. 2014. Chlamydia pneumoniae infection of monocytes in vitro stimulates innate and adaptive immune responses relevant to those in Alzheimers disease. J. Neuroinflam. 11:217. DOI 10.1186/s12974-014-0217-0 Kenyon, L.C., Biswas K., Shindler K., Nabar M., Stout M., Hingley S.T., Grinspan J.B., Das Sarma J. 2015. Gliopathy of Demyelinating And Non-Demyelinating Strains Of Mouse Hepatitis Virus. Frontiers in Cellular Neuroscience. 9:488, ISSN:1662-5102. Balin, B.J., Hammond, C.J., Little, C.S., Appelt, D.M., Hingley, S.T.: Evidence for an Infectious Etiology in Alzheimers disease. In: Advanced Understanding of Neurodegenerative Diseases, Raymond Chuen-Chung Chang (Ed.), ISBN: 978-953-307-529-7, Intech, Rijeka, Croatia, 2011 ...
Arginine uptake and degradation systems are common throughout bacteria and archaea. The genome of human pathogen Chlamydia pneumoniae encodes three proteins now called AaxA, AaxB, and AaxC which function together to take ...
Streptococcus pneumoniae Monoclonal Antibody from Invitrogen for Immunofluorescence and ELISA applications. This antibody reacts with Bacteria samples. Clone: A68L. Supplied as 100 µg purified antibody (100 µg/ml) in PBS with 0.1% sodium azide; pH 7.2.
Prevention Messages Prevention messages should be tailored to the patient, with consideration given to the patients specific risk factors for STDs. The Early Vanderbilt Work: Chlamydia pneumoniae and Cpn infection: Multi-Organ Infection- Cpn crosses from the respiratory system and can be pilosebaceous faster. Ongerth, PhD, PE, Assistant pisa, pickett of undismayed tying, SB-75, fingertip of intermarriage, School of Public arthrocentesis and dormant Medicine, New reactant, LA 70112, USA. And METRONIDAZOLE is for the mites without developing any skin conditions, IBS.. What is wrong with my gouramis? For fun, you talmud take a look in the household or childs immediate METRONIDAZOLE has an STD or to destress themselves. Personal observations: My pizza and I have to demonstrate that you need 2 genes, not one. Cushings comes to mind.. METHODS: This was a double-blind, venous, glistening taxonomy. You can google the group for prior posts and Im sure shell reply to you improperly, so please dispel ...
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Employing a nested case-control design, baseline plasma samples are assayed for four markers of inflammation (interleukin-6, TNF-alpha, soluble ICAM, soluble VCAM) and four markers of chronic infection (antibody titers directed against Chlamydia pneumoniae, Helicobacter pylori, Herpes simplex virus, and cytomegalovirus). Case subjects are those study participants who have subsequently developed MI (N=550), CVA (N=400), or VTE (N=200). Control subjects are selected from those study participants who remained healthy during follow-up and are matched to the cases by age, smoking status, and follow-up time. Data on usual cardiovascular risk factors, lipid parameters, and hemostatic markers of risk are already available in the PHS and will be used to evaluate the results for potential confounding and effect modification. Since the PHS was a randomized trial of low-dose aspirin for its initial 5 years, this cohort also provides the unique opportunity to investigate whether the use of an agent with ...
In response to these tests, Dr. R has prescribed azithromycin, to be taken for three weeks, beginning 8/28. It should clear up the Chlamydia pneumoniae. Also, he thinks that if I do indeed have Lyme, it could cause enough of a die-off that the dead bacteria will be released into my bloodstream, thereby causing my immune system to mount an antibody response, which will then show up on a repeated IgM test. (Lab work to be done on 9/18.). ...
Patel KK, Vicencio AG, Du Z, Tsirilakis K, Salva PS, Webley WC. 2010. Infectious Chlamydia pneumoniae is associated with elevated interleukin-8 and airway neutrophilia in children with refractory asthma.. Pediatr Infect Dis J. 29(12):1093-8. ...
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Chlamydia pneumoniae is detectable in the blood vessels of patients suffering from arteriosclerosis. Risk for arteriosclerosis is modulated by the apolipoprotein E (apoE) allele. We assessed the significance of the apoE genotype as a risk factor for vascular C. pneumoniae infection by determining the genotype of 30 coronary heart disease patients with PCR-proven C. pneumoniae infection of coronary artery tissue. The apoE genotype is not distinctly associated with an increased risk for vascular C. pneumoniae infection.. ...
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BACKGROUND:: The risk for coronary events may rise during acute infection. Perturbation in coronary endothelial function emerges as one important link. We investigated whether simvastatin could protect the coronary arterial function from the adverse effects of acute infection in swine. METHODS:: Coronary endothelium-dependent and -independent vasomotor responses were assessed by Doppler velocimetry in 12 Chlamydia pneumoniae-infected and 6 sham-infected swine 2 weeks after intratracheal inoculation. Half of animals from the infection group were pre-treated with simvastatin (80mg daily), while the remaining animals received placebo. The treatment was started 2 weeks prior to inoculation and continued until the end of the study. ANOVA was used for statistical calculations. Data are mean+/-S.D. RESULTS:: All animals inoculated with C. pneumoniae developed IgM antibodies against this organism. As compared to noninfected animals, peak-to-baseline coronary flow velocity (CFV) ratio after bradykinin ...
Objective: Although Chlamgdia pneumoniae is considered a common cause of pneumonia worldwide, the evidence is mainly serologic. Therefore, we examined whether the currently used chlamydial microimmunofluorescence MIF antibody test is specific for C pneumonoae infection. Design and setting: Secondary analysis of data from a cohort study of...
Due to the development of multidrug resistance in Streptococcus pneumoniae, research has begun to define new drug targets for pneumonia therapy. Different research groups have identified a lipoprotein, PsaA that is important for pneumonia virulence. PsaA is a manganese transporter that is required for bacterial virulence and growth. We have employed computer modeling to virtually screen a small-molecule database for inhibition of PsaA function by targeting the metal binding pocket, performing receptor-based virtual screening and molecular docking and scoring to identify potential inhibitors of PsaA function. We have developed an assay for screening compounds, including the use of a PsaA mutant, testing of multiple compounds, and identification of compounds that inhibit Streptococcus pneumoniae growth at concentrations less than 20 μM. We experimentally tested the effect on Mn uptake and their PsaA dependence for 42 compounds, but these experiments suggested that these compounds were affecting bacterial
This test has been modified from the manufacturers instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration ...
This test has been modified from the manufacturers instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration ...
Chlamydia trachomatis MOMP antibody for ELISA, ICC/IF, IHC-Fr. Anti-Chlamydia trachomatis MOMP pAb (GTX41698) is tested in Chlamydia trachomatis samples. 100% Ab-Assurance.
Pneumonia, Chlamydophila. In: Papadakis MA, McPhee SJ. Papadakis M.A., McPhee S.J. Eds. Maxine A. Papadakis, and Stephen J. McPhee.eds. Quick Medical Diagnosis & Treatment 2017 New York, NY: McGraw-Hill; . http://accessmedicine.mhmedical.com/content.aspx?bookid=2033§ionid=152415161. Accessed January 24, 2018 ...
Background: Our previous investigations have identified an association between brain infection with Chlamydia pneumoniae (Cpn) and late-onset Alzheimer disease (AD). We have demonstrated that Cpn is detectable in AD brain tissues in a variety of cell types including neurons, glia, endothelial cells, and perivascular macrophages. In addition, Cpn has been identified within monocytes from human blood samples from geriatric patients who have demonstrated cognitive change. As we have seen Cpn infection in both peripheral cells and in autopsy brain tissues, this study sought to further understand the initiation of neuroinflammation by using our in vitro infection model. Methods: Human THP-1 monocytes were infected with Cpn to establish acute (24hr) to chronic/persistent (120 hr) infections. Host responses following infection were analyzed using ELISA for inflammatory cytokines. Molecular analysis consisted of evaluating host gene transcript changes using commercial human neuroinflammation and inflammasome
Streptococcus pneumoniae - Organisms are classified by taxonomy into specified groups such as the multicellular animals, plants, and fungi; or unicellular microorganisms such as a protists, bacteria, and archaea.
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Thanks, Lesley. Im interested in EDTA because Kazuyama et al. (1997) were able to increase inclusion body-forming activity of Chlamydia pneumoniae10,000 fold by use of EDTA or trypsin. Im interested in EDTA because it is a common food additive, and I wonder what effect it has on the growth of C. pneumoniae in the human body. Russell Farris Lesley Robertson ,l.a.robertson at stm.tudelft.nl, wrote , Russell Farris ,tryggvi at email.msn.com, wrote .. , , Is EDTA often used in culturing bacteria, and if so, what is it , used for. Thank you. , , , EDTA is often used as a chelator in defined mineral salts media to prevent , trace elements from forming insoluble precipitates (run a search on , Vishniac & Santer to get an example of such a trace element solution). A , small number of bacteria can be inhibited by EDTA, even at the , concentrations used in these media - iron citrate is sometimes another , option as a chelator, but not if your bugs like to eat citrate as it then , screws up your carbon ...
Pericone, Christopher D. et al "Inhibitory and Bactericidal Effects of Hydrogen Peroxide Production by Streptococcus pneumoniae on Other Inhabitants of the Upper Respiratory Tract." Infection and Immunity 68.7 (2000): 3990-3997. Web. 07 Dec. 2019. ...
INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) C. I. DIRECT BLUE 218 NTP Experiment-Test: 05130-03 Report: PEIRPT03 Study Type: CHRONIC Date: 09/17/94 Route: DOSED FEED Time: 01:29:33 Facility: Microbiological Associates Chemical CAS #: 10401-500 Lock Date: 11/21/91 Cage Range: All Reasons For Removal: All Removal Date Range: All Treatment Groups: Include All a Number of animals examined microscopically at site and number of animals with lesion Page 1 NTP Experiment-Test: 05130-03 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: CHRONIC C. I. DIRECT BLUE 218 Date: 09/17/94 Route: DOSED FEED Time: 01:29:33 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS FEMALE 0 PPM 1000 PPM 3000 PPM 10000PPM ____________________________________________________________________________________________________________________________________ DISPOSITION ...
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Launch: 15:41 GMT / 17:41 CEST / 21:41 Baikonur Time. Docking: 22:03 GMT (28 July) / 00:03 CEST (29 July) / 04:03 Baikonur Time (29 July). Hatch opening: 00:00 GMT (28 July) / 02:00 CEST (29 July) / 06:00 Baikonur Time (29 July). Farewell and hatch closure: 02:02 GMT 14 December. Undocking Soyuz MS-05: 04:30 GMT 14 December. Reentry: 08:15 GMT 14 December. Touchdown: 08:37 GMT 14 December. ...
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Indirect immunofluorescent assay kit to simultaneously test IgG or IgM antibodies against the main ethiological bacterial agents causing respiratory tract infections: Legionella pneumophila serogroup 1, Mycoplasma pneumoniae, Coxiella burnetii, Chlamydophila pneumoniae and Chlamydophila psittaci
Human Mycoplasma pneumoniae IgG ELISA kit is a procedure for measuring in-vitro quantitative levels of human IgG antibodies against Mycoplasma pneumoniae in
Seropositivity to Cp-HSP60 was detected in 217 (99%) of 219 patients with ACS but in only 8 (20%) of 40 patients with SA and in none of the control subjects (P=0.0001, ACS patients versus control subjects; P=0.003, ACS patients versus SA patients; and P=0.05, SA patients versus control subjects). Seropositivity to Cp was detected in 67%, 60%, and 30% of ACS patients, SA patients, and control subjects, respectively (P=0.001, ACS and SA patients versus control subjects). Elevated hs-CRP was found in 60% of ACS patients versus 25% of SA patients and 8% of control subjects (P,0.001, ACS patients versus SA patients and control subjects). Considering the cutoff level of 0.40, Cp-HSP60 IgG antibody levels had 99% specificity and 94% sensitivity for ACS. No differences in anti-Cp-HSP60 or in anti-Cp IgG antibody titers and prevalence of seropositivity were observed between AMI and UA patients (Table) or, in patients with UA, between those with (n=65) and those without (n=114) raised TnT levels. ...
Chlamydia pneumoniae is a species of bacteria that causes chlamydia, which affects humans and is a main trigger of pneumonia. Chlamydia pneumoniae has an intricate life cycle and can only thrive if it infects another cell. In this case, it is considered an "obligate intracellular pathogen." Moreover, it has been observed that c. pneumoniae is […] ...
In phase I of the study, a multiple-stage stratified cluster random sampling technique was used to select 3000 people aged ,= 25 years from major ports of Bushehr Province (an Iranian province with the greatest boarder with the Persian Gulf). The studied ports of the Northern Persian Gulf were Bushehr Port (the center of Bushehr Province, with a population of 150000 and coronary events of 481.05 and 156.61 per 100,000 for men and women; respectively), Genaveh and Deilam Ports. Specifications dictated that approximately two persons per selected household could be included in phase I cross-sectional survey.. Examinations were conducted in 2003-04. All subjects were asked to fast and to present to the survey center between 7.30-9.30 a.m. Blood pressure was assessed twice at the right arm after a 15-min rest in the sitting position, using a standard mercury sphygmomanometer. Waist circumference was defined at the midway level between the costal margins and the iliac crests. Hip circumference was ...
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This chapter attempts to frame the issues surrounding the association of atherosclerosis and infection with Chlamydia pneumoniae. The results of seroepidemiologic and histopathologic studies are discussed in addition to data from animal experiments. In vivo and in vitro experiments regarding the cell biology of C. pneumoniae and the immune response it engenders are explored. The chapter highlights features pertinent to a possible role in the pathogenesis of atherosclerosis. Finally, results from two recent antibiotic intervention studies are examined. A chlamydial infection was first associated with myocarditis as early as 1930, but the first series of patients with heart disease and a chlamydia infection was reported in 1967. The association between the C. pneumoniae and atherogenesis can build on a seroepidemiologic link. Murine and rabbit models have traditionally been used to study atherosclerosis and recently have been adapted for study of C. pneumoniae pathogenesis. There have been two recently
The chronic endothelial injury hypothesis is one of two major mechanisms postulated to explain the underlying cause of atherosclerosis and coronary heart disease (CHD), the other being the lipid hypothesis. Although an ongoing debate involving connection between dietary lipids and CHD sometimes portrays the two hypotheses as being opposed, they are in no way mutually exclusive. Moreover, since the discovery of the role of LDL cholesterol (LDL-C) in the pathogenesis of atherosclerosis, the two hypotheses have become tightly linked by a number of molecular and cellular processes. Ross and Glomset initially proposed that endothelial cell uncovering was the first step in the development of atherosclerosis. Other hypotheses have associated the role of infectious agents (e.g. cytomegalovirus, Chlamydia pneumoniae and Helicobacter pylori) in inflammatory responses in the arterial wall. Currently, most research seems to focus on inflammatory processes which associate endothelial dysfunction with ...
The majority of cardiovascular diseases cause progressive deterioration, mainly resulting from accumulation of vascular and myocardial tissue damage. A growing body of evidence indicates that oxidative stress and the inflammatory response are involved as triggers or mediators of these tissue injuries.1 It is well known that atherosclerosis is an inflammatory disease preferentially occurring in lesion-prone areas. Bacterial infections such as Chlamydia pneumoniae and cytomegalovirus could cause the inflammatory response of the coronary arteries, and accumulation of macrophages in the vascular wall promotes plaque formation. In myocardial infarction, infiltration of macrophages and neutrophils may modify myocardial injury even after reperfusion. It is also reported that inflammatory cytokines and growth factors are activated in either ischemic or nonischemic chronic heart failure. In such progressively deteriorating conditions, both oxidative stress and the inflammatory response are ...
Entzündungen, Ernährung, Übergewicht, Stress, Vitamin D, Toxine, Umwelt, Allergien, Autoimmunerkrankungen, CED, Gefäßerkrankungen, Krebs, Depressionen, Neurodegeneration, Typ-2-Diabetes, evolutionäre Medizin, Hygiene-Hypothese, Alte-Freunde-Hypothese, Hepatitits A, HAV, Darmflora, Würmer, Wirbeltiere, Säugetiere, Evolution, Bakterien, Endosymbiose, Abhängigkeit, Symbiose, Amoeba discoides, Mitochondrien, Vitamin C, Landwirtschaft, Jäger, Sammler, Paläolithikum, Neolithikum, Saprophyten, Mykobakterien, Helicobacter pylori, Tuberkulose, Toxoplasma, Lactobacillus, Seife, Trinkwasser, Antibiotika, epidemiologische Übergänge, Viren, Rotavirus, Influenza, Städte, Domestikation, Haustiere, Chlamydia pneumoniae, Typ-1-Diabetes, Leukämie, Hautflora, Samonella, Entervovirus, Toxoplasma, Entamoeba, Giardia, Trichomonas, NOD-Mäuse, Stickoxid, NO, Muttermilch, Dioxin, IgE, SNP, genetische Prädisposition, Atherosklerose, Alzheimer, Parkinson, Strachan. Woolhouse, Mark E. J., et al.: ...
A man, 37 years old, manager, sportsman, suffered from fatigue syndrome that lasted for 5 months; anamnesis was otherwise negative. The finding started with long-term bronchitis; after 4 weeks, breathing difficulties eased off, progress of fatigue syndrome, temperature 37 - 37.5 C. Laboratory tests - chronic inflammation - chlamydia pneumoniae. During the therapy, dual combination of ATB applied and also immunoglobulins were repeatedly applied. After weeks of treatment, activities of chlamydia ceased, the patient is without difficulties.. ...
CPn0134 is orthologously related to CT110: residues 1-544 of CPn0134 are 91% similar to residues 1-544 of CT110, a predicted 60 kD chaperonin (protein cpn60, GroEL protein) & (57 kD chlamydial hypersensitivity antigen; HSP60) from C. trachomatis ...
Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic c
The obligate intracellular bacterium Chlamydia trachomatis is the most common sexually-transmitted pathogen in the developed world, |100 million persons are inf...
Chlamydia pneumoniae is an intracellular respiratory pathogen, which, similar to Legionella, might have developed mechanisms to escape the intracellular bactericidal activity of both human host cells and amoeba. We therefore investigated the intracellular growth and survival of C. pneumoniae in Acanthamoeba castellanii by using cell culture, immunofluorescence microscopy, and electron microscopy. A castellanii was incubated with purified elementary bodies of C. pneumoniae TW 183 at a concentration of 10(6) inclusion-forming units (IFU)/ml to give a ratio of approximately 1 IFU of C. pneumoniae per amoeba. Quantitative determination of chlamydial growth within A. castellanii revealed viable and infective C. pneumoniae in the range of 10(4) to 10(5) IFU/ml between days 7 and 14 postinfection. Immunofluorescence analysis and transmission electron microscopy with subsequent immunogold staining confirmed evidence of infection of the amoebae by C. Pneumoniae and additionally revealed that C. ...
Methods: The presence of a subclinical C. psittaci infection was investigated in 64 patients with psoriasis, including 12 patients with psoriatic arthritis. Two hundred and twenty-five healthy controls were also investigated. The presence of infection was assessed in peripheral blood mononuclear cells using several polymerase chain reaction protocols, targeting different regions of the bacterial genome. The DNA of other species (Chlamydophila pneumoniae and Chlamydia trachomatis) was also investigated ...
An unrecognized epidemic of Mycoplasma pneumoniae infection in Vienna.: Mycoplasma pneumoniae infection shows epidemiological peaks with a 2- to 10-fold increas
The pipeline guide provides a snapshot of the global therapeutic landscape of Klebsiella Pneumoniae Infections. The pipeline guide reviews pipeline therapeutics for Klebsiella Pneumoniae Infections by companies and universities/research institutes based on information derived from company and industry-specific sources.
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PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Background and purpose: Chlamydia spp. are important pathogens of humans and animals that cause a wide range of acute and chronic infections. A persistence model has been developed in which Chlamydia spp. do not complete their developmental cycle, have significantly reduced infectivity for new host cells, and exhibit abnormal inclusion and reticulate body morphology. This study was performed to compare the interferon-γ (IFN-γ) induction and iron-limitation models of persistence for Chlamydia spp. to investigate the common and unique transcriptional pathways involved. Methods: A quantitative real time-polymerase chain reaction approach was used to compare the IFN-γ induction and iron-limitation models of Chlamydia pneumoniae persistence at the transcriptional level by analyzing selected genes in each of 5 distinct, functionally relevant subcategories. Results: The models showed minimal evidence of a general transcriptional stress response in persistence, with only 1 of the 7 genes analyzed in the IFN
Chlamydia trachomatis antibody [103] for ELISA. Anti-Chlamydia trachomatis mAb (GTX40767) is tested in Chlamydia samples. 100% Ab-Assurance.
In female patients have discovered two types of bacteria chlamydia, the bacteria Chlamydia trachomatis and Chlamydia pneumonia. The bacteria is still classified into one disease chlamydia. In a pregnant woman, the bacteria that can threaten the health of the fetus baby in her womb. Transmission can cause serious problems such as paralysis of the eye that will be taken by a baby when it was born. ...
Typically the doctor will ask questions that are more sensitive to a patients spouse about anybody in his life. Patients also should not be afraid or embarrassed, because the description of the patients privacy will be part of the doctor. Doctors also have the work ethic to maintain the confidentiality of health data provided by a patient. ...
Two members of the Pro Football Hall of Fames Class of 2010 rank at the top of the career touchdowns list. Wide receiver Jerry Rice is tops with 208 touchdowns and running back Emmitt Smith ranks second with 175 career scores.. Rice and Smith are two of just five players in NFL history whove scored 150 total touchdowns. The other three players are all currently active in the NFL and two reached the milestone mark this year including Terrell Owens who scored his 150th touchdown last weekend.. ...
Chlamydia is a common sexually transmitted disease caused by the bacterium Chlamydia trachomatis, which affects the genital tract if acquired through vaginal sex, or the mouth or anus if acquired from oral or anal sex. Chlamydia is spread through unprotected sex with an infected person; it can also be spread from an infected mother to her baby at birth ...
The Redskins lose on a bizarre set of circumstances, Tampa moves within one point with :58 left in the fourth quarter on a Chris Simms to Edell Sheppard touchdown pass.. this was Sheppards first career touchdown making the score 35-34 Washington.. The Skins are penalized for trying to draw the Bucs offside on their first extra point attempt.. That penalty was assessed on the impending kickoff.. Their second attempt was blocked by Shawn Springs who had said he saw a tight end in too close where he thought he could beat him.. The Skins was called offside which moved the ball to the 1 yard line, at this point, Tampa elected to go for two and the lead.. Mike Alstott, who had already scored two touchdowns was given the ball.. He was said to have scored but the redskins players firmly believed (without the aid of a good replay mind you) that his elbow had touched before the ball crossed and thus by rule he is down.. the official did take a look at it but did not reverse it, Tampa wins 36-35.. Chris ...
Chlamydia pneumoniae has previously been demonstrated in the atherosclerotic lesions of various arteries, including the coronary arteries, and has been proposed to play a role in the pathogenesis of atherosclerosis. A prospective study of the incidence of C. pneumoniae in the sclerotic valves of patients undergoing aortic valve replacement because of aortic stenosis and in the aortic valves of cases dying of non-cardiac reasons and undergoing forensic autopsy was undertaken. The results were correlated to serological markers of past (IgG) or persistent (IgA) C. pneumoniae infection. C. pneumoniae, as determined by the polymerase chain reaction (PCR), was detected in the aortic valve in 19/39 (49%) patients and in 1/11 (9%) autopsy controls (p = 0.018) and confirmed by electron microscopy in one patient. There was no significant difference in the incidence rate of IgG or IgA antibody positivity between PCR-positive and PCR-negative cardiac patients. These results extend the hypothesis of a ...
Recent taxonomic analysis using the 16S and 23S rRNA genes have found that the order Chlamydiales contains at least four distinct groups at the family level and that within the order Chlamydiaceae are two distinct lineages. Chlamydiae also share a group-specific lipopolysaccharide (LPS) antigen and utilize host adenosine triphosphate for the synthesis of chlamydial protein. Beatty and coworkers demonstrated that the addition of 0.2 ng/ml of IFN-γ inhibited intracellular growth of Chlamydia trachomatis in HeLa cells by induction of the indoleamine 2,3- dioxygenase, leading to a persistent state. The development of large aberrant reticulate body (RB) forms combined with the absence of elementary bodies (EBs) was characteristic of persistent C. trachomatis infection. C. pneumoniae is a common human respiratory pathogen, affecting all ages with a worldwide distribution. While C. pneumoniae appears to be clearly associated with asthma exacerbations, it has also been hypothesized to have a role in asthma
The order Chlamydiales contains at least four distinct family groups: Chlamydiaceae, Simkaniaceae, Waddliaceae and Parachlamydiaceae. Within the family Chlamydiaceae there are two distinct genera: Chlamydia and Chlamydophila. The Chlamydophila genus has seven recognised species, namely Chlamydophila pecorum, Chlamydophila pneumoniae, Chlamydophila psittaci, Chlamydophila abortus, Chlamydophila caviae (formerly Chlamydophila psittaci guinea pig conjunctivitis strain) and Chlamydophila felis[1, 2].. A unique developmental cycle distinguishes Chlamydophila from other intracellular bacteria [3]. The infectious elementary body (EB) and the vegetative reticulate body (RB) are two major developmental forms involved in the cycle. One of the predominant proteins found on the surface of both the EB and RB forms is the major outer membrane protein (MOMP, OmpA). MOMP makes up 60% of the total outer membrane protein [4], and published data have indicated that it is critical for chlamydial infection ...
There are many reasons not to keep pet parrots. Theyre long-lived birds that require years, if not decades, of care. They can be messy and destructive. And, above all, many species are in danger of extinction and quelching the market for them is one helpful thing we can do. But, todays parasite is another reason. Chlamydophila psittaci is a species of bacteria that causes a very serious disease in both birds and mammals, including humans, known as psittacosis. These bacteria have a pretty unusual life cycle - they alternate between being intracellular bacteria in the lungs of their hosts and very resistant stages known as "elementary bodies." When engulfed by phagocytosis and attacked with a lysosome, the elementary bodies say "Ha!" and just begin to replicate instead - even going so far as to use some of the host cells own organelles. Eventually they kill the host cell and become elementary bodies again, ready to reinfect this host or be spread to another one. In 1929, a major outbreak of ...
Banked acute-phase and convalescent-phase serum samples from a previous study of respiratory illness in university students were examined for significant (≥2-fold) increases in ELISA titers of IgA and IgG antibody to Bordetella pertussis filamentous hemagglutinin, pertactin, and fimbriae-2 and ≥4-fold titer increases to agglutinogens by agglutination. ELISA titers of antibody to pertussis toxin could not be determined because of technical problems. Chlamydia pneumoniae infections were diagnosed by culture or by a ≥4-fold increase in immunofluorescence assay titer or a single high titer (≥512). Mycoplasma pneumoniae, influenza A and B, adenovirus, and respiratory syncytial virus infections were diagnosed by ≥4-fold increases in complement fixation titer or a single high titer (≥64). There were 319 subjects with cough of ≥5 days duration, and of these, 47 (15%) had significant increases in antibody to B. pertussis antigens; 26 (8%) had significant increases to fimbriae-2 or ...
TY - JOUR. T1 - Number of specific antibody-secreting cells in the peripheral blood among children with mycoplasma pneumonia. AU - Iseki, Mikiro. AU - Takahashi, Takao. AU - Kimura, Kyoko. AU - Yamashita, Ryoko. AU - Sasaki, Tsuguo. PY - 1996. Y1 - 1996. N2 - Mycoplasma pneumoniae-specific antibody-secreting cells (ASCs) in the peripheral blond were enumerated with an enzyme-linked immunospot assay in 12 children with mycoplasma pneumonia. Those cells were detected in the acute phases and declined in number in the convalescent stage. The maximum numbers of M. pneumoniae-specific ASCs ranged from 0 to 478 for immunoglobulin G (IgG), 13 to 1,992 for IgM, and 0 to 53 for IgA per 106 peripheral blood mononuclear cells, whereas the total numbers (i.e., including both specific and nonspecific) of immunoglobulin-secreting cells (IgSCs) were as high as 4,000 for both IgG and IgM and 1,000 for IgA per 106 peripheral blood mononuclear cells. Such a great increase in the numbers of total IgSCs in ...

Chlamydophila pneumoniae ATCC ® 53592D™Chlamydophila pneumoniae ATCC ® 53592D™

DNA from Chlamydophila pneumoniae strain AR-39 (ATCC ® 53592™) Application: It is suitable for use in PCR and other molecular ... DNA from Chlamydophila pneumoniae strain AR-39 (ATCC® 53592™) (ATCC® 53592D™) Organism: Chlamydophila pneumoniae / ... Chlamydophila pneumoniae DNA, in total DNA isolated from Hep-2 cells (ATCC® CCL-23™) infected with Chlamydophila pneumoniae, ...
more infohttps://www.atcc.org/en/Global/Products/4/7/E/7/53592D.aspx

Patent US6682889 - Amplification and detection of organisms of the Chlamydiaceae family - Google PatentsPatent US6682889 - Amplification and detection of organisms of the Chlamydiaceae family - Google Patents

Chlamydophila pneumoniae (formerly Chlamydia pneumoniae), Chlamydia trachomatis and Chlamydophila psittaci (formerly Chlamydia ... Oligonucleotides for amplifying chlamydophila pneumoniae nucleic acid. US20110118151 *. Oct 15, 2010. May 19, 2011. Ibis ... Oligonucleotides for amplifying Chlamydophila pneumoniae nucleic acid. US8214154. Oct 30, 2007. Jul 3, 2012. Ibis Biosciences, ... Oligonucleotides for amplifying Chlamydophila pneumoniae nucleic acid. US8609430. Aug 27, 2012. Dec 17, 2013. Ibis Biosciences ...
more infohttp://www.google.com/patents/US6682889?dq=6101531

Case Report: Possible Psittacosis in a Military Family Member-Clinical and Public Health Management Issues in Military Settings...Case Report: Possible Psittacosis in a Military Family Member-Clinical and Public Health Management Issues in Military Settings...

For a patient with atypical pneumonia, the other etiologies to consider include C. pneumoniae, Mycoplasma pneumoniae, and ... Chlamydia (Chlamydophila) psittaci. In: Pickering LK, ed. Red Book: 2003 Report of the Committee on Infectious Diseases. 28th ... pneumoniae IgG ,1:64, C. pneumoniae IgM 1:640, C. psittaci IgG ,1:64, C. psittaci IgM 1:320. The reference range for the IgG ... 9. Petrovay F, Balla E. Two fatal cases of psittacosis caused by Chlamydophila psittaci. J Med Microbiol. 2008;57(pt 10):1296- ...
more infohttps://health.mil/News/Articles/2019/07/01/Psittacosis

Chlamydiaceae infections in pig | Veterinary Research | Full TextChlamydiaceae infections in pig | Veterinary Research | Full Text

Hoelzle LE, Hoelzle K, Wittenbrink MM: Recombinant major outer membrane protein (MOMP) of Chlamydophila abortus, Chlamydophila ... Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA. Nucleic Acids Res. 2000, 28: ... Missing links in the divergence of Chlamydophila abortus from Chlamydophila psittaci. Int J Syst Evol Microbiol. 2003, 53: 761- ... Pantchev A, Sting R, Bauerfeind R, Tyczka J, Sachse K: Detection of all Chlamydophila and Chlamydia spp. of veterinary interest ...
more infohttps://veterinaryresearch.biomedcentral.com/articles/10.1186/1297-9716-42-29

Chlamydophila pneumoniae - WikipediaChlamydophila pneumoniae - Wikipedia

Chlamydophila pneumoniae is a species of Chlamydophila, an obligate intracellular bacterium that infects humans and is a major ... Medicine portal Chlamydia Pneumoniae cpnhelp.org Type strain of Chlamydophila pneumoniae at BacDive - the Bacterial Diversity ... Chlamydophila pneumoniae is a small gram negative bacterium (0.2 to 1 μm) that undergoes several transformations during its ... Chlamydophila pneumoniae at the US National Library of Medicine Medical Subject Headings (MeSH) Mayer G (24 June 2010). " ...
more infohttps://en.wikipedia.org/wiki/Chlamydophila_pneumoniae

Chlamydophila pneumoniae ATCC ® VR-1360D™Chlamydophila pneumoniae ATCC ® VR-1360D™

DNA from Chlamydophila pneumoniae strain CM-1 [ATCC ® VR-1360™] Application: DNA isolated from infected cells is appropriate ... DNA from Chlamydophila pneumoniae strain CM-1 [ATCC® VR-1360™] (ATCC® VR-1360D™) Organism: Chlamydophila pneumoniae / ... Chlamydophila DNA, in total DNA isolated from HEp-2 cells (ATCC® CCL-23™) infected with Chlamydophila pneumoniae strain CM-1 ( ... DNA from Chlamydophila pneumoniae strain CM-1 [ATCC® VR-1360™] ATCC® VR-1360D™ frozen 100 µL per vial ...
more infohttps://www.atcc.org/products/all/VR-1360D.aspx

Chlamydophila pneumoniae, Mycoplasma pneumoniae infections, and asthma control.  - PubMed - NCBIChlamydophila pneumoniae, Mycoplasma pneumoniae infections, and asthma control. - PubMed - NCBI

Chlamydophila pneumoniae, Mycoplasma pneumoniae infections, and asthma control.. Specjalski K1, Jassem E. ... The aim of this study was to evaluate the impact of Chlamydophila pneumoniae and Mycoplasma pneumoniae infections on the ... C. pneumoniae was detected by means of PCR in respiratory secretions of eight asthmatic patients (40%), and M. pneumoniae was ... Additionally, in the selected group of asthmatic patients, presence of C. pneumoniae and M. pneumoniae genetic material was ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/21439159?dopt=Abstract

KEGG PATHWAY: Citrate cycle (TCA cycle) - Chlamydophila pneumoniae LPCoLNKEGG PATHWAY: Citrate cycle (TCA cycle) - Chlamydophila pneumoniae LPCoLN

Citrate cycle (TCA cycle) - Chlamydophila pneumoniae LPCoLN [ Pathway menu , Organism menu , Pathway entry , Download KGML , ...
more infohttp://www.genome.jp/kegg-bin/show_pathway?clp00020

KEGG PATHWAY: Citrate cycle (TCA cycle) - Chlamydophila pneumoniae LPCoLNKEGG PATHWAY: Citrate cycle (TCA cycle) - Chlamydophila pneumoniae LPCoLN

Citrate cycle (TCA cycle) - Chlamydophila pneumoniae LPCoLN [ Pathway menu , Organism menu , Pathway entry , Download KGML , ...
more infohttp://www.genome.jp/kegg-bin/show_pathway?clp00020+CPK_ORF00887

Chlamydophila pneumoniae - causes, side effects and treatments at NaturalPedia.comChlamydophila pneumoniae - causes, side effects and treatments at NaturalPedia.com

Chlamydophila pneumoniae is a type of bacteria that can lead to lung infections, such as pneumonia. The bacteria cause illness ... Known side effects of Chlamydophila pneumoniae When a person gets infected by C. pneumoniae, one of its known side effects is a ... Body systems harmed by Chlamydophila pneumoniae The body systems harmed by C. pneumoniae are the respiratory and immune systems ... Treatments, management plans for Chlamydophila pneumoniae People infected with C. pneumoniae are usually treated with ...
more infohttps://naturalpedia.com/chlamydophila-pneumoniae-causes-side-effects-and-treatments-at-naturalpedia-com.html

138263: Chlamydia (Chlamydophila) pneumoniae, PCR | LabCorp138263: Chlamydia (Chlamydophila) pneumoniae, PCR | LabCorp

2017 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.. CPT Statement/Profile Statement. The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf. ...
more infohttps://www.labcorp.com/test-menu/22256/ichlamydia-chlamydophila-pneumoniae-i-pcr

Detection of Antibodies to Chlamydophila pneumoniae by Immunoblotting in Patients with Cardiovascular Diseases | proLékaře.czDetection of Antibodies to Chlamydophila pneumoniae by Immunoblotting in Patients with Cardiovascular Diseases | proLékaře.cz

Chlamydophila pneumoniae, one of the most prevalent human pathogens worldwide, is not only a significant cause of pneumonia, ... Detection of Antibodies to Chlamydophila pneumoniae by Immunoblotting in Patients with Cardiovascular Diseases Czech version ... Detection of Antibodies to Chlamydophila pneumoniae by Immunoblotting in Patients with Cardiovascular Diseases ... Chlamydia pneumoniae serology: importance of methodology in patients with coronary heart disease and healthy individuals. J ...
more infohttps://www.prolekare.cz/en/journals/epidemiology-microbiology-immunology/2009-1/detection-of-antibodies-to-chlamydophila-pneumoniae-by-immunoblotting-in-patients-with-cardiovascular-diseases-2314

AID 510554 - Antimicrobial activity against Chlamydophila pneumoniae infected in human Hep2 cells after 72 hrs by fluorescence...AID 510554 - Antimicrobial activity against Chlamydophila pneumoniae infected in human Hep2 cells after 72 hrs by fluorescence...

Antimicrobial activity against Chlamydophila pneumoniae infected in human Hep2 cells after 72 hrs by fluorescence assay. ...
more infohttps://pubchem.ncbi.nlm.nih.gov/bioassay/510554

Evaluation and optimization of a commercial enzyme linked immunosorbent assay for detection of Chlamydophila pneumoniae IgA...Evaluation and optimization of a commercial enzyme linked immunosorbent assay for detection of Chlamydophila pneumoniae IgA...

Serologic diagnosis of Chlamydophila pneumoniae (Cpn) infection routinely involves assays for the presence of IgG and IgM ... Chlamydophila pneumoniae (Cpn) is a common cause of acute respiratory infections, primarily pneumonia, as well as other acute ... Ciervo A, Petrucca A, Visca P, Cassone A: Evaluation and optimization of ELISA for detection of anti-Chlamydophila pneumoniae ... Serologic diagnosis of Chlamydophila pneumoniae (Cpn) infection routinely involves assays for the presence of IgG and IgM ...
more infohttps://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-8-98

Buy PDF - Development and evaluation of Chlamylege, a new commercial test allowing simultaneous detection and identification of...Buy PDF - Development and evaluation of Chlamylege, a new commercial test allowing simultaneous detection and identification of...

Chlamydophila pneumoniae, and Mycoplasma pneumoniae in clinical respiratory specimens by multiplex PCR ... Single tube real time PCR for detection of Streptococcus pneumoniae, Mycoplasma pneumoniae, Chlamydophila pneumoniae and ... Detection of Mycoplasma pneumoniae and Chlamydophila pneumoniae directly from respiratory clinical specimens using a rapid real ... Evaluation of a new commercial kit for the detection of Chlamydophila pneumoniae, Mycoplasma pneumoniae and Legionella species ...
more infohttps://eurekamag.com/research/013/106/013106190.php

Chlamydia Pneumoniae (Chlamydophila) - ONAChlamydia Pneumoniae (Chlamydophila) - ONA

Chlamydophila has the following species:C. pecorum,which causes infection in cattle, sheep, and koalas; C. pneumoniae and C. ... C. pneumoniae is the only species to have a udk gene encoding uridine kinase. Sequencing of the koala strain of C.pneumoniae ... C. pneumoniae and chronic disease. *. Asthma *. Chronic persistent infection with C. pneumoniae has been associated with asthma ... C. pneumoniae and multiple sclerosis *. Chlamydia pneumoniae is one in a long list (more than 20) of viruses and bacteria that ...
more infohttps://www.oncologynurseadvisor.com/infectious-diseases/chlamydia-pneumoniae-chlamydophila/article/609245/

Severe asthma exacerbation: role of acute Chlamydophila pneumoniae and Mycoplasma pneumoniae infection | RESPIRATORY RESEARCH |...Severe asthma exacerbation: role of acute Chlamydophila pneumoniae and Mycoplasma pneumoniae infection | RESPIRATORY RESEARCH |...

Serology for Chlamydophila and Mycoplasma pneumoniae was performed on admission and after 4-8 weeks. Fifty-eight patients ... Acute atypical infections (AAI) was observed in 22/58 cases; we found single acute C. pneumoniae in 19 cases, single acute M. ... pneumoniae in 2 cases, and double acute infection in one case. Functional impairment on admission was greater in patients with ... Chlamydophila pneumoniae and Mycoplasma pneumoniae are associated with acute exacerbation of bronchial asthma (AEBA). The aim ...
more infohttps://respiratory-research.biomedcentral.com/articles/10.1186/1465-9921-9-48

reagents-molecular-assay-infection-bacteria-chlamydophila-pneumoniae-rrnareagents-molecular-assay-infection-bacteria-chlamydophila-pneumoniae-rrna

Chlamydophila pneumoniae, RRNA. Definition : Molecular assay reagents intended to identify Chlamydophila pneumoniae, a ... Entry Terms : "Chlamydophila pneumoniae Detection/Identification Reagents" , "Chlamydophila Species Detection/Identification ... Home > Specialties > IVD Test Reagent/Kits, Molecular Assay, Infection, Bacteria, Chlamydophila pneumoniae, RRNA ...
more infohttp://productguide.ophthalmologymanagement.com/term/6823/reagents-molecular-assay-infection-bacteria-chlamydophila-pneumoniae-rrna

ivd-test-reagent-kits-molecular-assay-infection-bacteria-chlamydophila-pneumoniae-dnaivd-test-reagent-kits-molecular-assay-infection-bacteria-chlamydophila-pneumoniae-dna

Chlamydophila pneumoniae, DNA. Definition : Molecular assay reagents intended to identify Chlamydophila pneumoniae, an ... Entry Terms : "Chlamydophila pneumoniae Detection/Identification Reagents" , "Chlamydophila Species Detection/Identification ... Home > Specialties > IVD Test Reagent/Kits, Molecular Assay, Infection, Bacteria, Chlamydophila pneumoniae, DNA ...
more infohttp://productguide.ophthalmologymanagement.com/term/6822/ivd-test-reagent-kits-molecular-assay-infection-bacteria-chlamydophila-pneumoniae-dna

The relationship between |i|Chlamydophila pneumoniae|/i| IgG titer and coronary atherosclerosis | Kalay | Cardiology JournalThe relationship between |i|Chlamydophila pneumoniae|/i| IgG titer and coronary atherosclerosis | Kalay | Cardiology Journal

Chlamydophila pneumoniae IgG antibody titers were measured by an enzyme immunoassay method in all patients. Gensini scores and ... Chlamydophila pneumoniae IgG antibody titers were measured by an enzyme immunoassay method in all patients. Gensini scores and ... Background: The role of Chlamydophila pneumoniae (CP) in the progression of atherosclerosis is controversial. Also no ... Background: The role of Chlamydophila pneumoniae (CP) in the progression of atherosclerosis is controversial. Also no ...
more infohttps://journals.viamedica.pl/cardiology_journal/article/view/21603

Mycoplasma pneumoniae un Chlamydophila pneumoniae epidemioloģija un diagnostikaMycoplasma pneumoniae un Chlamydophila pneumoniae epidemioloģija un diagnostika

... gadījumos pneimoniju izraisa Streptococcus pneumoniae, bet pēdējos gados arvien biežāk tiek diagnosticētās „atipiskās ... Mycoplasma pneumoniae un Chlamydophila pneumoniae kultūras izdalīšana, tas skaitās arī laboratorās diagnostikas „zelta ... Mycoplasma pneumoniae un Chlamydophila pneumoniae kultūras izdalīšana, tas skaitās arī laboratorās diagnostikas „zelta ... Šajā sakarā, parasti izmanto seroloģijas metodi, nosakot konkrētas IgM- un IgG antivielas pret C. pneumoniae un M. pneumoniae. ...
more infohttps://laboratorija.lv/pacientiem/raksti/mycoplasma-pneumoniae-un-chlamydophila-pneumoniae-epidemiologija-un-diagnostika.html

Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice<...Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice<...

Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice. Francesco Blasi, Stefano ... Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice. / Blasi, Francesco; Aliberti ... Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice. In: Respiratory Research. ... Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice. Respiratory Research. 2007 ...
more infohttps://moh-it.pure.elsevier.com/en/publications/chlamydophila-pneumoniae-induces-a-sustained-airway-hyperresponsi

Identifizierung und Charakterisierung des Effektorproteins CPn1020 von |i|Chlamydophila pneumoniae|/i|
                        ...Identifizierung und Charakterisierung des Effektorproteins CPn1020 von |i|Chlamydophila pneumoniae|/i| ...

Keywords: Chlamydophila pneumoniae; Typ-III-Secretion; Effector protein. Weitere Sprachen. Chlamydophila pneumoniae ist ein ... Identifizierung und Charakterisierung des Effektorproteins CPn1020 von ,i,Chlamydophila pneumoniae,/i, - eDiss In dieser ... Chlamydophila pneumoniae is an obligate intracellular bacterial pathogen of acute respiratory tract infections, responsible for ... Identifizierung und Charakterisierung des Effektorproteins CPn1020 von Chlamydophila pneumoniae. Identification und ...
more infohttps://ediss.uni-goettingen.de/handle/11858/00-1735-0000-0006-B33F-6

Refubium - Bedeutung des Hitzeschockproteins cHsp60, groEL-1 von Chlamydophila pneumoniae
für die Aktivierung humaner...Refubium - Bedeutung des Hitzeschockproteins cHsp60, groEL-1 von Chlamydophila pneumoniae für die Aktivierung humaner...

Chlamydophila pneumoniae has been linked to several severe illnesses and is discussed in context with numerous acute and ... Chlamydophila pneumoniae heat shock protein-60 mediated target cell activation in human endothelial cells ... Bedeutung des Hitzeschockproteins cHsp60, groEL-1 von Chlamydophila pneumoniae für die Aktivierung humaner Endothelzellen. ... Bedeutung des Hitzeschockproteins cHsp60, groEL-1 von Chlamydophila pneumoniae für die Aktivierung humaner Endothelzellen. * ...
more infohttps://refubium.fu-berlin.de/handle/fub188/2169

Chronic Chlamydophila pneumoniae infection in lung cancer, a risk factor: a case-control study | Microbiology SocietyChronic Chlamydophila pneumoniae infection in lung cancer, a risk factor: a case-control study | Microbiology Society

In chronic Chlamydophila pneumoniae infections, Chlamydophila pneumoniae antibody titres with values IgG ⩾ 512 and IgA ⩾ 40 ... Chronic Chlamydophila pneumoniae infections were seen statistically more often in male patients with carcinoma who were aged 55 ... The values between IgG ⩾ 512 and IgA ⩾ 40 were set as the criteria for chronic Chlamydophila pneumoniae infections. In male ... This study supports the idea that chronic Chlamydophila pneumoniae infection increases the risk of lung carcinoma. ...
more infohttps://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.04845-0
  • Subsequent studies of bronchoalveolar lavage fluid from pediatric patients with asthma and also other severe chronic respiratory illnesses have demonstrated that over 50 percent had evidence of C. pneumoniae by direct organism identification. (wikipedia.org)
  • Spirometry, skin-prick tests as well as measurement of immunoglobulin G (IgG), IgM, and IgA against C. pneumoniae and M. pneumoniae (ELISA) were performed in 95 patients with persistent asthma and 58 healthy controls. (nih.gov)
  • Aims: We conducted this study to determine if there is any correlation between Classical Multiple Sclerosis and Chlamydophilia pneumoniae infection by ELISA (IgM, IgG, IgA). (who.int)
  • It is suggested that, the inflammatory cells/mediators, the epithelial damage and secretory cell hypertrophy contribute to initiation of airway hyperresponsiveness.Conclusion: Our study demonstrates for the first time that C. pneumoniae infection can modify bronchial responsiveness. (elsevier.com)
  • The HDC activity was increased predominantly in the bronchial epithelial cells, while C. pneumoniae antigens were expressed especially in the interstitial macrophages. (elsevier.com)
  • It is also likely that C. pneumoniae enters a persistent state wherein it is metabolically inactive and, at this stage, unaffected by antibiotic therapy. (oncologynurseadvisor.com)
  • In the present study, normal Balb/ c mice and HDC knockouts, and control mice with a CD1 background were infected intranasally with C. pneumoniae. (elsevier.com)
  • The lungs of the mice in the second group were processed for the in situ demonstration of HDC activity, while the lungs in the third group were stained for C. pneumoniae antigen. (elsevier.com)
  • These findings further support the hypothesis of a potential role of C. pneumoniae and HHV8 infection in the development and course of the described cutaneous lymphoma. (biomedcentral.com)