Chitosan
Chitin
Drug Carriers
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Nanoparticles
Hexuronic Acids
Glucuronic Acid
Biocompatible Materials
Chemistry, Pharmaceutical
Alginates
Holmium
Spectroscopy, Fourier Transform Infrared
Drug Delivery Systems
Delayed-Action Preparations
Drug Compounding
Nanocapsules
Microspheres
Technology, Pharmaceutical
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
Mode of action of chitin deacetylase from Mucor rouxii on N-acetylchitooligosaccharides. (1/1030)
The mode of action of chitin deacetylase from the fungus Mucor rouxii on N-acetylchitooligosaccharides with a degree of polymerization 1-7 has been elucidated. Identification of the sequence of chitin oligomers following enzymatic deacetylation was verified by the alternative use of two specific exo-glycosidases in conjunction with HPLC. The results were further verified by 1H-NMR spectroscopy. It was observed that the length of the oligomer is important for enzyme action. The enzyme cannot effectively deacetylate chitin oligomers with a degree of polymerization lower than three. Tetra-N-acetylchitotetraose and penta-N-acetylchitopentaose are fully deacetylated by the enzyme, while in the case of tri-N-acetylchitotriose, hexa-N-acetylchitohexaose and hepta-N-acetylchitoheptaose the reducing-end residue always remains intact. Furthermore, the enzyme initially removes an acetyl group from the nonreducing-end residue of all chitin oligomers with a degree of polymerization higher than 2, and further catalyses the hydrolysis of the following acetamido groups in a processive fashion. The results are in agreement with the mode of action that the same enzyme exhibits on partially deacetylated water soluble chitosan polymers. (+info)Chs7p, a new protein involved in the control of protein export from the endoplasmic reticulum that is specifically engaged in the regulation of chitin synthesis in Saccharomyces cerevisiae. (2/1030)
The Saccharomyces cerevisiae CHS7 gene encodes an integral membrane protein located in the ER which is directly involved in chitin synthesis through the regulation of chitin synthase III (CSIII) activity. In the absence of CHS7 product, Chs3p, but not other secreted proteins, is retained in the ER, leading to a severe defect in CSIII activity and consequently, to a reduced rate of chitin synthesis. In addition, chs7 null mutants show the yeast phenotypes associated with a lack of chitin: reduced mating efficiency and lack of the chitosan ascospore layer, clear indications of Chs7p function throughout the S. cerevisiae biological cycle. CHS3 overexpression does not lead to increased levels of CSIII because the Chs3p excess is retained in the ER. However, joint overexpression of CHS3 and CHS7 increases the export of Chs3p from the ER and this is accompanied by a concomitant increase in CSIII activity, indicating that the amount of Chs7p is a limiting factor for CSIII activity. Accordingly, CHS7 transcription is increased when elevated amounts of chitin synthesis are detected. These results show that Chs7p forms part of a new mechanism specifically involved in Chs3p export from the ER and consequently, in the regulation of CSIII activity. (+info)Modification of chitosan to improve its hypocholesterolemic capacity. (3/1030)
Cholestyramine is the most widely used bile acid sequestrant in the treatment of hypercholesterolemia. However, cholestyramine has unpleasant side effects as a consequence of its hydrophobic backbone. Therefore, high-capacity bile acid sequestering biopolymers with cationic chitosan derivatives were developed, because electrostatic interactions are important for binding with bile acid anions. Dialkylaminoalkylation and reductive amination of chitosan were done to add dialkylaminoalkyl and an additional free amino group at a hydroxyl site in the chitosan backbone respectively and the amino-derivatized chitosan derivatives were quaternized with methyl iodide to produce a cationic polyelectrolyte. The in vitro bile acid binding capacity of the chitosan derivatives in aqueous NaCl was measured by reversed-phase HPLC. The binding capacities of sodium glycocholate (a major bile acid) to chitosan, DEAE-chitosan, quaternized DEAE-chitosan, and cholestyramine were 1.42, 3.12, 4.06, and 2.78 mmol/g resin, respectively. With quaternized DEAE-chitosan, the bile acid binding capacity increased approximately 50% over that of cholestyramine. The bile acid binding capacity of dialkylaminoalkyl chitosan derivatives increased with the number of carbons in the alkyl groups, indicating that hydrophobic interaction is a secondary factor for the sequestration of bile acids. (+info)Development of bacterial contamination during production of yeast extracts. (4/1030)
Baker's yeast suspensions having bacterial populations of 10(6) and 10(8) CFU/ml were subjected to autolysis processes designed to obtain yeast extracts (YE). The bacterial contaminants added to the yeast cell suspensions were produced with spent broths obtained from a commercial yeast production plant and contained 59% cocci (Leuconostoc, Aerococcus, Lactococcus) as well as 41% bacilli (Bacillus). Autolyses were conducted at four different pH levels (4.0, 5.5, 7.0, and 8.5) and with two autolysis-promoting agents (ethyl acetate and chitosan). Processing parameters were more important than the initial bacterial population in the development of contaminating bacteria during manufacture of YE. Drops in the viable bacterial population after a 24-h autolysis were observed when pH was adjusted to 4.0 or when ethyl acetate was added. A significant interaction was found between the effects of pH and autolysis promoters on the bacterial population in YE, indicating that the activity of ethyl acetate, as opposed to that of chitosan, was not influenced by pH. (+info)Oligogalacturonic acid and chitosan reduce stomatal aperture by inducing the evolution of reactive oxygen species from guard cells of tomato and Commelina communis. (5/1030)
Stomatal opening provides access to inner leaf tissues for many plant pathogens, so narrowing stomatal apertures may be advantageous for plant defense. We investigated how guard cells respond to elicitors that can be generated from cell walls of plants or pathogens during pathogen infection. The effect of oligogalacturonic acid (OGA), a degradation product of the plant cell wall, and chitosan (beta-1,4-linked glucosamine), a component of the fungal cell wall, on stomatal movements were examined in leaf epidermis of tomato (Lycopersicon esculentum L.) and Commelina communis L. These elicitors reduced the size of the stomatal aperture. OGA not only inhibited light-induced stomatal opening, but also accelerated stomatal closing in both species; chitosan inhibited light-induced stomatal opening in tomato epidermis. The effects of OGA and chitosan were suppressed when EGTA, catalase, or ascorbic acid was present in the medium, suggesting that Ca(2+) and H(2)O(2) mediate the elicitor-induced decrease of stomatal apertures. We show that the H(2)O(2) that is involved in this process is produced by guard cells in response to elicitors. Our results suggest that guard cells infected by pathogens may close their stomata via a pathway involving H(2)O(2) production, thus interfering with the continuous invasion of pathogens through the stomatal pores. (+info)Maintenance of CD34 expression during proliferation of CD34+ cord blood cells on glycosaminoglycan surfaces. (6/1030)
Recent studies have indicated that glycosaminoglycan (GAG) interactions with hematopoietic progenitors play a significant role in the regulation of hematopoiesis. However, the details of these interactions are not clear. In this study, we examined the role of soluble and immobilized GAGs in the proliferation of CD34+ cells. Chitosan, a cationic polysaccharide, was used to immobilize GAGs in ionic complex membranes. The GAGs studied were heparin, hyaluronate, and chondroitin sulfates A, B, and C. CD34-enriched umbilical cord blood cells were seeded onto tissue culture plates coated with the GAG-chitosan complex membranes. Cultures were maintained in medium supplemented with stem cell factor and interleukin 3 for up to six weeks, during which total and CD34+ cell numbers were determined by flow cytometry. Total cell number expansion ranged from 25-fold to 40-fold after six weeks. However, only heparin and chondroitin sulfate B (CSB) surfaces retained a significant CD34+ fraction. All other surfaces exhibited declines in CD34 expression, with negligible CD34+ percentages remaining after four weeks. In contrast, heparin and CSB surfaces exhibited CD34+ fractions as high as 90% after four weeks. GAG desorption studies indicated that the observed effects were partly mediated by desorbed GAGs in a concentration dependent manner. Subsequent studies showed that sustained high (160 microg/ml) heparin levels had toxic effects, while the same concentration of CSB exhibited more rapid early proliferation of CD34+ cells. In conclusion, this culture system has demonstrated the ability to produce simultaneous proliferation and CD34+ cell enrichment of a partially purified cord blood population by controlling the nature and levels of GAG moieties to which the cells are exposed. The results indicate that specific GAGs can significantly influence the growth and differentiation characteristics of cultured CD34+ cells. (+info)Purification, characterization, and gene analysis of a chitosanase (ChoA) from Matsuebacter chitosanotabidus 3001. (7/1030)
The extracellular chitosanase (34,000 M(r)) produced by a novel gram-negative bacterium Matsuebacter chitosanotabidus 3001 was purified. The optimal pH of this chitosanase was 4.0, and the optimal temperature was between 30 and 40 degrees C. The purified chitosanase was most active on 90% deacetylated colloidal chitosan and glycol chitosan, both of which were hydrolyzed in an endosplitting manner, but this did not hydrolyze chitin, cellulose, or their derivatives. Among potential inhibitors, the purified chitosanase was only inhibited by Ag(+). Internal amino acid sequences of the purified chitosanase were obtained. A PCR fragment corresponding to one of these amino acid sequences was then used to screen a genomic library for the entire choA gene encoding chitosanase. Sequencing of the choA gene revealed an open reading frame encoding a 391-amino-acid protein. The N-terminal amino acid sequence had an excretion signal, but the sequence did not show any significant homology to other proteins, including known chitosanases. The 80-amino-acid excretion signal of ChoA fused to green fluorescent protein was functional in Escherichia coli. Taken together, these results suggest that we have identified a novel, previously unreported chitosanase. (+info)Characterization of a novel, antifungal, chitin-binding protein from Streptomyces tendae Tu901 that interferes with growth polarity. (8/1030)
The afp1 gene, which encodes the antifungal protein AFP1, was cloned from nikkomycin-producing Streptomyces tendae Tu901, using a nikkomycin-negative mutant as a host and screening transformants for antifungal activity against Paecilomyces variotii in agar diffusion assays. The 384-bp afp1 gene has a low G+C content (63%) and a transcription termination structure with a poly(T) region, unusual attributes for Streptomyces genes. AFP1 was purified from culture filtrate of S. tendae carrying the afp1 gene on the multicopy plasmid pIJ699. The purified protein had a molecular mass of 9,862 Da and lacked a 42-residue N-terminal peptide deduced from the nucleotide sequence. AFP1 was stable at extreme pH values and high temperatures and toward commercial proteinases. AFP1 had limited similarity to cellulose-binding domains of microbial plant cell wall hydrolases and bound to crab shell chitin, chitosan, and cell walls of P. variotii but showed no enzyme activity. The biological activity of AFP1, which represents the first chitin-binding protein from bacteria exhibiting antifungal activity, was directed against specific ascomycetes, and synergistic interaction with the chitin synthetase inhibitor nikkomycin inhibited growth of Aspergillus species. Microscopy studies revealed that fluorescein-labeled AFP1 strongly bound to the surface of germinated conidia and to tips of growing hyphae, causing severe alterations in cell morphogenesis that gave rise to large spherical conidia and/or swollen hyphae and to atypical branching. (+info)
HMWC - High Molecular Weight Chitosan | AcronymFinder
IJMS | Free Full-Text | Molecular Weight Dependent Glucose Lowering Effect of Low Molecular Weight Chitosan Oligosaccharide ...
Molecules | Free Full-Text | Sulfated Chitosan Oligosaccharides Suppress LPS-Induced NO Production via JNK and NF-κB...
Investigation of chitosan nanoparticles durability in combination with antioxidant-antibacterial fraction extracted from...
United States Carboxymethyl Chitosan Market 2017- DOW, CP Kelco, AKZO Nobel, UGUR Seluloz Kimya, Quimica Amtex - Herald Analyst
Preparation of cross-linked chitosan microspheres by spray drying: Effect of cross-linking agent on the properties of spray...
Global Chitosan Derivatives Market 2016 Definitions, Applications and Industry Chain Structure by 2021 - BizPR.co.uk | UK Free...
Effect of the high molecular weight chitosan and sodium alginate on Candida albicans hydrophobicity and adhesion to cells
Solid‐phase modification of chitosan hydrogel membranes and permeability properties of modified chitosan membranes<...
Improvement of osteoblast functions by sustained release of bone morphogenetic protein-2 (BMP-2) from heparin-coated chitosan...
Betaxolol Hydrochloride Loaded Chitosan Nanoparticles for Ocular Delivery and their Anti-glaucoma Efficacy | Bentham Science
Chitosan|High density chitosan|Water Soluble Chitosan|Chitosan oligosaccharide|D-glucosamine Hcl|D-Glucosamine Sulfate(2Kcl...
A novel effective therapeutic approach for treatment of Leishmania tropica through Miltefosine Loaded Chitosan Nanoparticles |...
Global Chitosan Derivatives Market Trends, Challenges and Growth Drivers Analysis 2021 | Medgadget
Global Chitosan Sales Market Research by Production,Revenue,Market Manufacturer & Region-in Depth Analysis Report 2017 - BizPR...
Sitemap | Chitin Manufacturers, Chitosan Derivatives, Chitosan Suppliers in India
Adsorption of indomethacin onto chemically modified chitosan beads<...
Recovery of Lipids from Aqueous Dispersions with Chitosan Solutions, Russian Journal of Applied Chemistry | 10.1023/B:RJAC...
Effect of single or combined administration of resistant starch and chitosan oligosaccharides on insulin resistance in rats fed...
Effects of Chitosan Oligosaccharide and/or Beta-Glucan Supplementation to Diets Containing Organic Zinc on Performance and Some...
Chitosan Oligosaccharide Liquid
USP,Chitosan oligosaccharide,148411-57-8, View 148411-57-8, GKSW Product Details from Baoji Guokang Bio-Technology Co., Ltd....
Iodinated Echogenic Glycol Chitosan Nanoparticles for X-ray CT/US Dual Imaging of Tumor [Abstract]
A Photo-Crosslinkable Chitosan Hydrogel for Peripheral Nerve Anastomosis - Semantic Scholar
KNUSTSpace: Effects of ph of medium and molecular weight on polyelectrolyte complex formation between pectin and chitosan
Chitosan Films Incorporated with Exopolysaccharides from Deep Seawater Alteromonas sp.
Patent US4833237 - Process for producing granular porous chitosan - Google Patents
Published paper on Use of combined nanocarrier system based on chitosan nanoparticles and phospholipids complex for improving...
The Unusual Bell-Like Dependence of the Activity of Chitosan against Penicillium Vermoesenii on Chitosan Molecular Weight -...
Frontiers | Poly(ethylene glycol) and Cyclodextrin-Grafted Chitosan: From Methodologies to Preparation and Potential...
Weight Loss Benefits of Chitosan - Phentramin-D
Physicochemical features and transfection properties of chitosan/polox | IJN
DSpace at EWHA: Effects of tumor microenvironments on targeted delivery of glycol chitosan nanoparticles
Preparation, characterization and evaluation of antibacterial activity of catechins and catechins-Zn complex loaded β-chitosan...
Separation of phytosterols using chitosan from Penaeus Monodon - UMS INSTITUTIONAL REPOSITORY
Greenwich Academic Literature Archive - An integrated buccal delivery system combining chitosan films impregnated with peptide...
Effects of chitosan and water-soluble chitosan micro- and nanoparticle | IJN
Antibacterial effects of chitosan/cationic peptide nanoparticles<...
Antibacterial efficacy of copper-added chitosan nanoparticles: a confocal laser scanning microscopy analysis | AVESİS
NutraGenesis Introduces Clinically Proven Blood Sugar Nutraceutical - Nutraceuticals World
Functional hybrid fibers of cellulose/microcrystalline chitosan. I. Manufacture of viscose/microcrystalline chitosan fibers<...
In vitro evaluation on CaCo-2 cells of hybrid lipid/chitosan nanoparticles for the oral delivery of heparin. | Archivio della...
TERBINAFINE LOADED CHITOSAN SCAFFOLD FOR FUNGAL WOUND TREATMENT | INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH
Enhanced oral absorption of hydrophobic and hydrophilic drugs using quaternary ammonium palmitoyl glycol chitosan nanoparticles...
Chitosan Oligosaccharide - Car Part - Vehicle Parts - Auto Parts & Accessories - Products - Cn-Jingyun.com
The influence of pH on the adsorption and interaction of chitosan with cellulose :: BioResources
中国科学院大连化学物理研究所机构知识库(DICP OpenIR): Chitosan oligosaccharides inhibit TNF-alpha-induced VCAM-1 and ICAM-1 expression in human...
Layer-by-Layer Assembly of Inactivated Poliovirus and N-Trimethyl Chitosan on pH-Sensitive Microneedles for Dermal Vaccination....
Functionality of chitosan‐halloysite nanocomposite films for sustained delivery of antibiotics: The effect of chitosan molar...
Effects of sodium acetate buffer on chitosan sponge properties and in vivo degradation in a rat intramuscular model - BIOQUANT...
Development of Dorzolamide Loaded 6-O-Carboxymethyl Chitosan Nanoparticles for Open Angle Glaucoma : Figure 11
Enhanced plumbagin production in Plumbago indica root culture by simultaneous and sequential dual elicitations using chitosan...
In-situ analysis of polyelectrolyte complexes by flow cytometry<...
Properties of chitosan-filled polypropylene (PP) composites: The effect of acetic acid
Physicochemical and Mechanical Properties of Composite of Chitosan Microspheres/Calcium Phosphate Cement
A new route for chitosan immobilization onto polyethylene surface
Biocompatible and Antibacterial Nitric Oxide-Releasing Pluronic F-127/Chitosan Hydrogel for Topical Applications[v1] | Preprints
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KR20050014100A - Functional tangmyen and Its preparation - Google Patents
Biodegradable injectable sheet as transscleral drug delivery system | IOVS | ARVO Journals
Global Chitosan Gel Market Research Report 2021
Layer-by-layer assemblies of chitosan and heparin: effect of ionic strength and pH
Chitosan Market for Water Treatment, Biomedicine & Pharmaceutics, Industrial, Food & Beverages, Cosmetics, Agrochemical and...
Indian Patents. 256134:A PROCESS FOR THE PREPARATION OF ALGINATE NANOPARTICLES
中国科学院大连化学物理研究所机构知识库(DICP OpenIR): Swelling behaviour of alginate-chitosan microcapsules prepared by external gelation or...
Ibuprofen loaded Chitosan/ Poly (maleic anhydride -alt -vinyl acetate) submicronic capsules for pain treatment - Laboratoire...
CiNii Articles - Anti-ulcer Effects of Chitin and Chitosan, Healthy Foods, in Rats
Composite System Based on Chitosan and Room-Temperature Ionic Liquid: Direct Electrochemistry and Electrocatalysis of...
Multifunctional Biomaterials from the Sea: Assessing the effects of Chitosan incorporation into Collagen Scaffolds on...
NAVER 학술정보 | Removal of azo dyes from aqueous solutions using chitosan based composite hydrogels
Complex Coacervates between a Lactose-Modified Chitosan and Hyaluronic Acid as Radical-Scavenging Drug Carriers | Archivio...
Preparation of novel tissue acidosis-responsive chitosan drug nanoparticles: Characterization and in vitro release properties...
Natural Polymer International Salaries, Average Salary & Jobs Pay
Novel biopolimeric system for bone tissue engineering: Crosslinked and plasticized chitosan/poly vinyl alcohol/hydroxiapatite...
WO1998012369A1 - Chitosan-containing acrylic fibers and process for preparing the same - Google Patents
Hybrid chitosan-alginate scaffolds for bone and cartilage tissue engineering
Inhibition of Glomerular Mesangial Cell Proliferation by siPDGF-B- and siPDGFR-beta-Containing Chitosan Nanoplexes
Effect of Chitosan Nanoparticles as Active Coating on Chemical Quality and Oil Uptake of Fish Fingers : Journal of Agriculture...
Polymeric Micelles of Modified Chitosan Block Copolymer as Nanocarrier for Delivery of Paclitaxel | Bentham Science
Evaluation of Removal Efficiency of Cr (VI) Ions from Aqueous Solution Using Chitosan
Calories in Stacker 3 With Chitosan Thermogenic Weight Loss Pill - Calories and Nutrition Facts | MyFitnessPal.com
Flocculation Chitosan
Pharmaceutical Microbiology Resources: New anti-fungal treatment
Ispitivanje sigurnosti primjene poloksamersko-kitozanskih micela s uklopljenim melatoninom na staničnom modelu epitela rožnice ...
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Application of nanoparticle in photodynamic diagnosis for colorectal cancer
Purification of DP 6 to 8 chitooligosaccharides by nanofiltration from the prepared chitooligosaccharides syrup | Bioresources...
Assembly of polyelectrolyte-containing block copolymers in aqueous media<...
Assessment of the Quorum Sensing Inhibition Activity of a Non-Toxic Chitosan in an N-Acyl Homoserine Lactone (AHL)-Based...
Chitosan-Based Macromolecular Biomaterials for the Regeneration of Chondroskeletal and Nerve Tissue - IMT Institutional...
Preparation and Properties of Hydroxyecdysone Microcapsules by Complex Coacervation - Dissertation
Appa Rao Podile
Moerschbacher, Bruno (26 March 2018). "13th International Conference on Chitin and Chitosan" (PDF). Chitosan. Retrieved 26 ...
Biofabrication
"Biofabrication with Chitosan". Biomacromolecules. 6 (6): 2881-2894. doi:10.1021/bm050410l. ISSN 1525-7797. PMID 16283704. v t e ...
Biopolymer
These properties allow for various biomedical applications of chitosan. Chitosan as drug delivery: Chitosan is used mainly with ... Chitosan as an anti-microbial agent: Chitosan is used to stop the growth of microorganisms. It performs antimicrobial functions ... Chitosan is another popular biopolymer in biomedical research.[according to whom?] Chitosan is derived from chitin, the main ... Chitosan composite for tissue engineering: Blended powder of chitosan along with alginate are used together to form functional ...
Cultured meat
The degree of this process determines the physical and chemical properties of the chitosan. Chitosan has antibacterial ... Chitosan is derived from chitin in a process known as alkaline deacetylation (substituting out certain amino acid groups). ... Chitosan's resemblance to glycosaminoglycans and internal interactions between glycoproteins and proteoglycans make it highly ... One potential disadvantage of chitosan is that it degrades in the presence of lysozymes (naturally occurring enzymes). But, ...
Shakeel Ahmed (scientist)
"Chitosan: Derivatives, Composites and Applications , Wiley". Wiley.com. "Biocomposites". Ahmed, Shakeel, ed. (September 16, ... Materials Applications of Advanced Green Materials Bionanocomposites in Tissue Engineering and Regenerative Medicine Chitosan ...
Nanorod
Wang, Chung-Hao; Chang, Chia-Wei; Peng, Ching-An (2010-12-18). "Gold nanorod stabilized by thiolated chitosan as photothermal ... Polymers, such as Polyethylene glycol (PEG), Polyallylamine hydrochloride (PAH) coating; dietary fibers, such as chitosan; or ...
Thiomer
"Chitosan and thiolated chitosan: Novel therapeutic approach for preventing corneal haze after chemical injuries". Carbohydr. ... "Chitosan and thiolated chitosan: Novel therapeutic approach for preventing corneal haze after chemical injuries". Carbohydr. ... Bae, IH; Jeong, BC; Kook, MS; Kim, SH; Koh, JT (2013). "Evaluation of a thiolated chitosan scaffold for local delivery of BMP-2 ... In case of thiolated chitosan, for instance, a more than 10,000-fold increase in viscosity within a few minutes was shown. ...
Natural fiber
One difference between chitin and chitosan is that chitosan is soluble in acidic aqueous solutions. Chitosan is easier to ... Chitosan is a deacetylated derivative of chitin. When the acetylated composition of the copolymer is below 50% it is chitosan. ... Due to its ease of processing, chitosan is used in biomedical applications. Collagen is a structural protein, often referred to ... Chitosan is a semicrystalline "polymer of β-(1-4)-2-amino-2-deoxy-D-glucose". ...
Electrophoretic light scattering
pKa values of chitosans can be calculated from the dependency of electrophoretic mobility values on pH and charge density. Like ... "Chitosan-graft-polyethylenimine as a gene carrier". Journal of Controlled Release. Elsevier BV. 117 (2): 273-280. doi:10.1016/j ... "Electrophoretic Light Scattering Studies of Chitosans with Different Degrees ofN-acetylation". Biomacromolecules. American ... proteins, the size and zeta potential of chitosans can be determined through ELS. ELS has also been applied to nucleic acids ...
Medical textiles
Chitosan hemostatic agents are salts formed when chitosan is combined with an organic acid (lactic acid, or Succinic acid). The ... Chitosan, a natural polymer that is biocompatible, non-allergenic, biodegradable, and non-toxic, was also looked at for its ... Chitosan may function as an inhibitor of bacterial and fungal development. In 2003, the United States Food and Drug ... Combat medics use Hemcon dressings, which is a dressing with Chitosan, to treat wounds because it stops the blood flow with its ...
PH-sensitive polymers
Chitosan, a frequently used example, is cationic. Since DNA is negatively charged, DNA could be attached to chitosan as a way ... Cao, Ye; Tan, Yang Fei; Wong, Yee Shan; Liew, Melvin Wen Jie; Venkatraman, Subbu (2019-06-25). "Recent Advances in Chitosan- ... Examples include chitosan, hyaluronic acid, alginic acid and dextran. ...
Sabine Piller
Lauto, A., Mawad, D., Barton, M., Gupta, A., Piller, S. C., & Hook3, J. (2010). Photochemical tissue bonding with chitosan ... Lauto, A., Mawad, D., Barton, M., Piller, S. C., & Longo, L. (2011). Chitosan Adhesive Films for Photochemical Tissue Bonding. ...
Aeroponics
The active ingredients in the ODC cannabis line contain the original active ingredient chitosan at 0.25%, as well as 0.28% ... "MATERIAL SAFETY DATA SHEET Colloidal Chitosan" (PDF). ODC™. "BEYOND Stoner 3x ODC™". www.aeroponics.com. Retrieved 2020-12-06. ...
Antimicrobial polymer
Chitosan is a nontoxic polymer that has displayed broad-spectrum antimicrobial activity. The mechanism of action for chitosan ... Growth inhibition and death of fungi, bacteria, and yeasts have been seen from chitosan. The antimicrobial effect of chitosan ... Although the antimicrobial effect is attributed to antifungal properties of chitosan, it may be possible that the chitosan acts ... Chitosan has been used as a coating and appears to protect fresh vegetables and fruits from fungal degradation. ...
Liver support system
Chitosan was added to cryogels as it promotes spheroid formation in hepatocytes, an indicator of healthy growth. The ... investigated poly(AN-co-NVP) and poly(NiPAAm)-chitosan cryogels as hepatocyte carriers in a BAL system. These cryogel polymers ... took this system a step further, utilising HepG2 seeded poly(NiPAAm)-chitosan cryogels in a bioreactor, along with an activated ... Li, Jieliang; Pan, Jilun; Zhang, Liguo; Yu, Yaoting (June 2003). "Culture of hepatocytes on fructose-modified chitosan ...
Catalase
Çetinus ŞA, Öztop HN (June 2003). "Immobilization of catalase into chemically crosslinked chitosan beads". Enzyme and Microbial ...
Artificial bone
Implants composed of chitosan and hydroxyapatite take advantage of chitosan's biocompatibility and its ability to be molded ... The composite formed by carbon nanotubes and chitosan greatly improves the toughness of chitosan. Nanostructured artificial ... Chitosan can also be used with carbon nanotubes, which have a high Young's modulus (1.0-1.8 TPa), tensile strength (30-200 GPa ... Chitosan by itself can be easily modified into complex shapes that include porous structures, making it suitable for cell ...
Nano-scaffold
Other natural biomaterials utilized include agarose and chitosan. Synthetic biomaterials include poly(ethylene glycol) (PEG) ...
Squid
ISBN 978-81-315-0104-7. Ifuku, S. (2014). "Chitin and chitosan nanofibers: preparation and chemical modifications". Molecules. ...
Autologous patient-specific tumor antigen response
Song S, Zhou F, Nordquist RE, Carubelli R, Liu H, Chen WR (June 2009). "Glycated chitosan as a new non-toxic immunological ... Chen WR, Korbelik M, Bartels KE, Liu H, Sun J, Nordquist RE (2005). "Enhancement of laser cancer treatment by a chitosan- ...
Sodium triphosphate
"Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers". Journal of Applied Polymer Science. 63 (1): ...
Tube-based nanostructure
"Nanostructured Hollow Tubes Based on Chitosan and Alginate Multilayers". Advanced Healthcare Materials. 3 (3): 433-440. doi: ...
Nanoparticle drug delivery
Common synthetic polymeric nanoparticles include polyacrylamide, polyacrylate, and chitosan. Drug molecules can be incorporated ...
Hydrogel
Liu X, Ma L, Mao Z, Gao C (2011), Jayakumar R, Prabaharan M, Muzzarelli RA (eds.), "Chitosan-Based Biomaterials for Tissue ... May 2013). "Ultrathin chitosan-poly(ethylene glycol) hydrogel films for corneal tissue engineering". Acta Biomaterialia. 9 (5 ... May 2012). "The use of chitosan based hydrogel for enhancing the therapeutic benefits of adipose-derived MSCs for acute kidney ... Materials such as collagen, chitosan, cellulose, and poly (lactic-co-glycolic acid) have been implemented extensively for drug ...
Molecular imprinting
Xu, L.; Huang, Y.; Zhu, Q.; Ye, C. (2015). "Chitosan in molecularly-imprinted polymers: Current and future prospects". ...
Nisin
Chandrasekar, Vaishnavi (2017). "Release Kinetics of Nisin from Chitosan-Alginate Complex Films". Journal of Food Science. 81 ( ...
Coagulation (water treatment)
"Critical assessment of chitosan as coagulant to remove cyanobacteria". Harmful Algae. 66: 1-12. doi:10.1016/j.hal.2017.04.011. ...
Zygomycota
After this the chitosan polymer chain forms micro fibrils. These fibers are embedded in an amorphous matrix consisting of ... Most fungi have chitin as structural polysaccharide, while zygomycetes synthesize chitosan, the deacetylated homopolymer of ... proteins, glucans (which putatively cross-link the chitosan fibers), mannoproteins, lipids and other compounds. Trisporic acid ...
Glycoside hydrolase family 19
Eijsink V, Hoell I, Vaaje-Kolstada G (2010-01-01). "Structure and function of enzymes acting on chitin and chitosan". ...
Dimethylol ethylene urea
"Application of low-molecular-weight chitosan in durable press finishing". Carbohydrate Polymers. 73 (2): 254-260. doi:10.1016/j ...
Effects of Chitosan on Immunological Enhancement
Chitosan Control Chitosan Control Chitosan 27. 24.17 ± 3.80. 25.30 ± 0.96. 37.2 ± 3.30† 45.90 ± 3.38‡ 38.77 ± 3.87† 88.50 ± ... Chitosan Control Chitosan Control Chitosan 27. 72.80 ± 12.74. 60.87 ± 15.90. 48.50 ± 11.00. 32.8 ± 15.50. 10.70 ± 2.54. 10.30 ... Chitosan induces different L-arginine metabolic pathways in resting and inflammatory macrophages.[3] Chitosan but not chitin ... Chitosan is one of a few natural cationic polysaccharides. A number of applications for chitosan have been proposed, including ...
Blended Chitosan Paste for Infection Prevention: Preliminary and Preclinical Evaluations
The preliminary studies with the chitosan paste delivered antibiotics to a contaminated musculoskeletal wound with hardware and ... Blended Chitosan Paste for Infection Prevention: Preliminary and Preclinical Evaluations Clin Orthop Relat Res. 2017 Jul;475(7 ... We blended chitosan/polyethylene glycol (PEG) pastes/sponges to increase biocompatibility and improve antibiotic coverage ... Questions/purposes: (1) Are blended chitosan/PEG pastes biodegradable? (2) Are the blended pastes biocompatible? (3) How much ...
Optimal immobilization of β-glucosidase into chitosan beads using response surface methodology | Zhou | Electronic Journal of...
Chitosan-olive oil microparticles for phenylethyl isothiocyanate delivery: Optimal formulation | PLOS ONE
For this, an optimisation process (factors: olive oil: chitosan ratio and PEITC: chitosan ratio) was implemented through a 3- ... Optimal conditions were olive oil: chitosan and PEITC: chitosan ratios of 1.46 and 0.25, respectively. These microparticles had ... So, polymeric microparticles were developed using chitosan-olive oil-PEITC systems. ...
Biodegradable Films from Phytosynthesized TiO2 Nanoparticles and Nanofungal Chitosan as Probable Nanofertilizers
The bioactive polymer chitosan and its NPs provide outstanding characteristics for capping and enhancements of nanometals. The ... whereas the fungal chitosan (FCt) was produced from ,i,Aspergillus brasiliensis,/i, biomass and was transformed to nanoform. ... Fungal Chitosan Extraction. The chitosan was effectually extracted from A. brasiliensis mycelia; the extracted FCt had a ... Preparation of Fungal Chitosan/TiO2-NP Composite. Grown mycelia of Aspergillus brasiliensis (ATCC-16404), after aerobic ...
Chitosan Market - Download Summary Form
Synthesis and Biological Activity of Drug Delivery System Based on Chitosan Nanocapsules
Synthesized naproxen/chitosan nanocapsules were assessed against both Gram positive bacterial strain such as Bacillus subtilis ... Different factors affecting on the size diameter of chitosan nanoparticles such as stirring time and temperature, pH values as ... Different factors affecting on the immobilization of naproxen into chitosan nanoparticles such as time, temperature and pH ... The morphology and diameter of the prepared chitosan nanoparticles was characterized using scanning electron microscopy and ...
chitosan | Homebrew Talk - Beer, Wine, Mead, & Cider Brewing Discussion Forum
Clearing Wine w/ Chitosan? Hi, all! So, after waiting a month for my Gewurztraminer to clear, I decided to keel to impatience ... bcuz I only had chitosan on hand. Its now been 3 days and its cloudier than ever. What... ... and add some chitosan to it to see if it would clear without adding the other component that it reacts with, ...
Injectable Chitosan-Based Thermosensitive Hydrogel/Nanoparticle-Loaded | IJN
Injectable Chitosan-Based Thermosensitive Hydrogel/Nanoparticle-Loaded System for Local Delivery of Vancomycin in the Treatment ... The VCM-NPs were formed with quaternary ammonium chitosan and carboxylated chitosan nanoparticles (VCM-NPs) by positive and ... We hypothesize that the positive charge of quaternary ammonium chitosan (QAC) and the negative charge of carboxylated chitosan ... Thermally triggered injectable chitosan/silk fibroin/bioactive glass nanoparticle hydrogels for in-situ bone formation in rat ...
Chitosan - Digital Naturopath
Because Chitosan is mostly indigestible, it can then prevent ... Chitosan has the unique ability to dissolve and bind to fats ... Chitosan. Chitosan has the unique ability to dissolve and bind to fats and cholesterol in the stomach. Because Chitosan is ... Chitin and chitosan are also now being taken like acidophilus, FOS, and other supplements to speed the transit of foods through ... Chitin and chitosan are nontoxic and free of side effects, although they share the same precautions for safe use that apply to ...
Chitosan and its Role in Ocular Therapeutics
| Bentham Science
Sustained and controlled ocular delivery can be achieved with chitosan based formulations like chitosan gels, inserts, chitosan ... Sustained and controlled ocular delivery can be achieved with chitosan based formulations like chitosan gels, inserts, chitosan ... This review discussed various aspects related to chitosan and chitosan based formulations particularly developed for ocular ... This review discussed various aspects related to chitosan and chitosan based formulations particularly developed for ocular ...
Chitosan-glucose combo eyed as novel preservative
The Maillard reaction product of chitosan and glucose extended the shelf-life of lamb in laboratory tests by two weeks, and may ... "From the present studies that the chitosan-glucose complex (CGC) is a better preservative than chitosan alone. It showed ... Chitosan-glucose combo eyed as novel preservative. By Stephen Daniells 29-Aug-2007. - Last updated on 19-Jul-2008 at 10:07. GMT ... The Maillard reaction product of chitosan and glucose extended the shelf-life of lamb in laboratory tests by two weeks, and may ...
PRIME PubMed | Direct electrochemistry and electrocatalysis of hemoglobin immobilized in a magnetic nanoparticles-chitosan film
Direct electrochemistry and electrocatalysis of hemoglobin immobilized in a magnetic nanoparticles-chitosan film. Download ... AnimalsBiosensing TechniquesCatalysisCattleChitosanElectrochemistryElectrodesElectron TransportFerrosoferric OxideHemoglobins ... The Fe(3)O(4) nanoparticles and chitosan (CS) were mixed to form a matrix in which haemoglobin (Hb) can be immobilized for the ... The Fe(3)O(4) nanoparticles and chitosan (CS) were mixed to form a matrix in which haemoglobin (Hb) can be immobilized for the ...
chitosan
Home » chitosan. Articles tagged with: chitosan. Bionics». Using injectable nano-network and ultrasound to help diabetics. By ... Tags: blood sugar levels, chitosan, diabetics, glucose levels, nanotechnology, north carolina state university, seaweed, shrimp ... researchers in Asia successfully managed to extract polymer chitosan from shrimp shells in order to make filters, foils and ...
Applications of Chitosan during the harvest
... and uses of chitosan to control the process. ... Applications of Chitosan during the harvest. Applications of ... The use of chitosan is already widespread due to its effectiveness in microbiological control, but new applications are still ... The authorization of the use of chitosan in oenology has opened the door to a new range of products with antimicrobial action. ... Chitosan during the harvest. Recording of the webinar held by Luis Cotanda. ...
Transmucosal cannabinoid formulation including a chitosan excipeint - Patent US-2019000794-A1 - PubChem
Mannosylated Chitosan-zinc Sulphide Nanocrystals as Fluorescent Bioprobes for Targeted Cancer Imaging - Amrita Vishwa...
Mannosylated Chitosan-zinc Sulphide Nanocrystals as Fluorescent Bioprobes for Targeted Cancer Imaging. Publication Type : ... Abstract : A novel nanomaterial based on chitosan-zinc sulphide:Mn (ZnS:Mn) conjugated with mannose ligand has been developed ... Deepthy Menon, "Mannosylated Chitosan-zinc Sulphide Nanocrystals as Fluorescent Bioprobes for Targeted Cancer Imaging", ... HomePublicationsMannosylated Chitosan-zinc Sulphide Nanocrystals as Fluorescent Bioprobes for Targeted Cancer Imaging ...
Effect of zeolites on chitosan/zeolite hybrid membranes for direct methanol fuel cell - NASA/ADS
... and HZSM-5 were incorporated into chitosan (CS) matrix to fabricate the hybrid membranes for direct methanol fuel cell (DMFC). ... Effect of zeolites on chitosan/zeolite hybrid membranes for direct methanol fuel cell *Wang, Jingtao ... Zeolites including 3A, 4A, 5A, 13X, mordenite, and HZSM-5 were incorporated into chitosan (CS) matrix to fabricate the hybrid ...
Inhibition of fibrillation of human serum albumin through interaction with chitosan-based biocompatible silver nanoparticles -...
Inhibition of fibrillation of human serum albumin through interaction with chitosan-based biocompatible silver nanoparticles† ... Inhibition of fibrillation of human serum albumin through interaction with chitosan-based biocompatible silver nanoparticles S ... The experimental observations indicate that interactions between HSA and chitosan-based silver nanoparticles have led to ... The results illustrate that the chitosan-mediated silver nanoparticles spontaneously bind to HSA without appreciable ...
Characterization of chitosan by steric exclusion chromatography - IRep - Nottingham Trent University
Journal name: Plant physiology / Publication Year: 1997 / Subject: chitosan / Subject term: chitosan - PubAg Search Results
... chitosan Remove constraint Subject: chitosan Subject term chitosan Remove constraint Subject term: chitosan Start Over ... Henn (Pgt),as well as chitin oligosaccharides, chitosan, and methyl jasmonate (MJ) stimulated lipoxygenase (LOX) activity (E.C ... protein synthesis; dose response; chitosan; seedlings; jasmonic acid; linoleate 13S-lipoxygenase; Puccinia graminis; Triticum ...
Antifungal whey protein films activated with low quantities of water soluble chitosan
Palabras clave: ACTIVE EDIBLE FILMS , ANTIFUNGAL AGENT , CROSSLINKING AGENT , WATER SOLUBLE CHITOSAN , WHEY PROTEIN ISOLATE ... Antifungal whey protein films activated with low quantities of water soluble chitosan. .noexiste{ color: #000; } .imagenItem{ ... added with low quantities of a water soluble derivative of chitosan (WSCh), which was obtained through a Maillard reaction with ... Antifungal whey protein films activated with low quantities of water soluble chitosan; Elsevier; Food Hydrocolloids; 110; ...
A REVIEW ON: CHITOSAN MICROSPHERE FOR COLONIC DRUG DELIVERY: INFLAMMATORY BOWEL DISEASE | Zenodo
... chitosan is natural polymer used as potential carrier for many drugs and also for many drug delivery such as topical, ... The objective of following review is to elaborate chitosan microsphere, ... The objective of following review is to elaborate chitosan microsphere, chitosan is natural polymer used as potential carrier ... Colon Targeted Delivery, Chitosan, Ulcerative Colitis, Microsphere, Mechanism Of Drug Release. Communities:. *INDO AMERICAN ...
Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles - Result
Probing insulins secondary structure after entrapment into alginate/chitosan nanoparticles. Research output: Contribution to ... Probing insulins secondary structure after entrapment into alginate/chitosan nanoparticles. / Sarmento, B.; Ferreira, D. C.; ... Probing insulins secondary structure after entrapment into alginate/chitosan nanoparticles. European Journal of Pharmaceutics ... Probing insulins secondary structure after entrapment into alginate/chitosan nanoparticles. In: European Journal of ...
Long lasting mucoadhesive membrane based on alginate and chitosan for intravaginal drug delivery<...
Since this alginate/chitosan membrane is stable in a simulated vaginal environment, is easy to fabricate and can be used for ... Since this alginate/chitosan membrane is stable in a simulated vaginal environment, is easy to fabricate and can be used for ... Since this alginate/chitosan membrane is stable in a simulated vaginal environment, is easy to fabricate and can be used for ... Since this alginate/chitosan membrane is stable in a simulated vaginal environment, is easy to fabricate and can be used for ...
chitosan | Winemaking Talk - Winemaking Forum
Eudragit® L100/chitosan composite thin bilayer films for intravaginal pH-responsive release of Tenofovir
- E-Prints...
Eudragit® L100/chitosan composite thin bilayer films for intravaginal pH-responsive release of Tenofovir ... In all the cases films structured in two layers - the upper layer mainly attributed to EL100 and the lower layer to chitosan - ... Bilayer films, Chitosan-based films, Eudragit® L100-based films, Films mechanical properties, Mucoadhesive vaginal films, ... Six batches of Tenofovir-loaded films were formulated based on Eudragit® L100 (EL100) and chitosan, containing triethyl citrate ...
In vitro and in vivo evaluation of gastro-retentive carvedilol loaded chitosan beads using GastroPlus™ - Simulations Plus
In vitro and in vivo evaluation of gastro-retentive carvedilol loaded chitosan beads using GastroPlus™. Authors: Praveen R, ... In conclusion, the study showed that gastro-retentive controlled release system prepared using chitosan could be a potential ... chitosan. 32 full factorial design was adopted for optimization of tripolyphosphate (X1) and curing time (X2). Bead stability ...
NanoparticlesCharacterizationChitinPolymer chitosanDerivativesHydrogelBiomaterialHydrogelsBiodegradableEffect of chitosanApplications of ChitosanPolysaccharideCarboxymethylMesenchymal stemVitroBiocompatibleCationicMolecular WeightPorousBacteriaShellfishDerivativeMembraneFTIRFecesShellsCompositeBiomaterialsConclusionPowderMembranesSolubilityToxicologicalExtractChemistryAqueousFormulationResearchersAntimicrobialFiberFormulationsRatioPolymericPhosphate2020SerumBiocompatibilityStomachGlucoseAbsorptionClinicalControlled ReleaseResults
Nanoparticles16
- The VCM-NPs were formed with quaternary ammonium chitosan and carboxylated chitosan nanoparticles (VCM-NPs) by positive and negative charge adsorption to enhance the encapsulation efficiency and drug loading of VCM, with the aim of simultaneously preventing infection and repairing broken bones. (dovepress.com)
- Sustained and controlled ocular delivery can be achieved with chitosan based formulations like chitosan gels, inserts, chitosan coated liposome/niosome and chitosan nanoparticles. (eurekaselect.com)
- The Fe(3)O(4) nanoparticles and chitosan (CS) were mixed to form a matrix in which haemoglobin (Hb) can be immobilized for the fabrication of H(2)O(2) biosensor. (unboundmedicine.com)
- The heterogeneous electron transfer rate constant (k(s)) was 1.04 s(-1), indicating great facilitation of the electron transfer between Hb and magnetic nanoparticles-chitosan modified electrode. (unboundmedicine.com)
- In this work, the mechanistic detail of the interaction between human serum albumin (HSA) and silver nanoparticles synthesized using nontoxic and biodegradable chitosan as a reducing and stabilizing agent, have been investigated at the nanobio interface. (rsc.org)
- The results illustrate that the chitosan-mediated silver nanoparticles spontaneously bind to HSA without appreciable conformational changes of the protein. (rsc.org)
- The experimental observations indicate that interactions between HSA and chitosan-based silver nanoparticles have led to appreciable reduction in amyloid fibril formation. (rsc.org)
- In this study, porous antibacterial collagenous scaffolds containing chitosan and selenium nanoparticles (SeNPs) as antibacterial agents were studied. (muni.cz)
- Barrier function measurements employing electric cell-substrate impedance sensing and analyses of tight junction-specific protein profiles have indicated that the alkylglyceryl-modified chitosan nanoparticles impact upon the integrity of the model blood-brain barrier, whereas confocal microscopy experiments have demonstrated the efficient cellular uptake and the perinuclear localization of these nanoparticles. (port.ac.uk)
- Munin: Chitosan Lecithin Nanoparticles with New Chemical Entity. (uit.no)
- A new chemical entity (NCE) encapsulated in chitosan/lecithin nanoparticles as well as NCE as a free drug was evaluated for potential cytotoxic effects by an in vitro MTT assay performed on HaCaT cells. (uit.no)
- IMSEAR at SEARO: Fabrication and Characterization of chitosan based polymeric Escitalopram nanoparticles. (who.int)
- The present study is focused on developing and characterizing chitosan based nanoparticles of Escitalopram oxalate (ETP). (who.int)
- Materials and Methods: The nanoparticles were prepared by ionic gelation method using chitosan and tripolyphosphate (TPP). (who.int)
- Conclusion: ETP loaded chitosan nanoparticles were prepared successfully from ionic gelation method, suggesting a comparatively suitable option for treatment of disease with fewer side effects and increased affinity of drug. (who.int)
- Herein, we present a microwave-assisted easy in situ solution casting approach for the manufacture of strontium oxide nanoparticles doped within a naturally occurring polymer, chitosan (CS), at varying weight percentages (2.5, 5, 10, 15, and 20 wt. (bvsalud.org)
Characterization1
- The results of the characterization of bioplastic films with the best performance are the addition of 7 mL sorbitol with a percentage of chitosan 4% with the result of 4.27 kgf / mm2 for tensile strength, 14% for elongation, percentage for water resistance of 90.6%, and positive friendly environment with biodegradability of bioplastic films as a whole for 6 days. (ummi.ac.id)
Chitin17
- Chitosan, produced by deacetylation of chitin, which is the structural element in the exoskeleton of crustaceans such as crab, shrimp, and crawfish and the cell wall of fungi, is a natural nontoxic biopolymer. (medscape.com)
- [ 3 ] Chitosan but not chitin activates the inflammasome by a mechanism dependent upon phagocytosis. (medscape.com)
- Chitin and chitosan were packed into nylon bags (3×1 cm2, 45 μm mesh) and administered orally, and then the bags were recovered from the feces. (researchgate.net)
- The present study showed that chitin did not undergo any changes in weight and shape in the gastrointestinal tract, whereas chitosan did. (researchgate.net)
- Chitin and chitosan are also now being taken like acidophilus , FOS, and other supplements to speed the transit of foods through the digestive system and to promote the growth of beneficial live bacteria in the intestines. (digitalnaturopath.com)
- Chitin (pronounced kite-in) and chitosan (kite-o-san) are fibers derived from marine animals. (digitalnaturopath.com)
- It is used to make various other substances, including chitosan, which is derived from chitin by heating it with a chemical solution. (digitalnaturopath.com)
- Chitosan, has the advantage of being more soluble in water than chitin Scientists have intensively investigated the properties and uses of chitin, chitosan, and their derivatives - collectively they are the subjects of approximately 1,000 scientific studies and hundreds of patents. (digitalnaturopath.com)
- Chitin and chitosan are nontoxic and free of side effects, although they share the same precautions for safe use that apply to other types of fiber. (digitalnaturopath.com)
- Chitin and chitosan should be taken separately from EFA supplements and vitamins, and before a high-fat or high-calorie meal. (digitalnaturopath.com)
- Although chitin and chitosan are considered non-allergenic, people with shellfish allergies should not take them, nor should pregnant or breastfeeding women. (digitalnaturopath.com)
- Aside efforts to utilize crustacean shells by extracting chitin and turning it into pharmaceuticals with fungi, researchers in Asia successfully managed to extract polymer chitosan from shrimp shells in order to make filters, foils and wound dressings. (robaid.com)
- Henn (Pgt),as well as chitin oligosaccharides, chitosan, and methyl jasmonate (MJ) stimulated lipoxygenase (LOX) activity (E.C. 1.13.11.12) in wheat (Triticum aestivum) leaves. (usda.gov)
- Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. (wileyiran.com)
- Chitin and Chitosan Preparation from Marine Sources. (semanticscholar.org)
- Chitin and chitosan are considerably versatile and promising biomaterials. (semanticscholar.org)
- Implantable applications of chitin and chitosan. (semanticscholar.org)
Polymer chitosan2
- The bioactive polymer chitosan and its NPs provide outstanding characteristics for capping and enhancements of nanometals. (hindawi.com)
- The polymer hydrogel treatment contains the naturally occurring polymer chitosan, extracted from shrimp shells, functionalized with a host molecule, cucurbit[8]uril , to form a cross-linked polymer network which provide structural stability. (creativepegworks.com)
Derivatives2
- And low-molecular-weight chitosan (LC) is one of chitosan derivatives and maintain beneficial biological properties of chitoson. (biomedcentral.com)
- Chitosan-Based Systems for Biopharmaceuticals provides a concise and up-to-date overview of the application of chitosan and its derivatives in the development and optimization of biopharmaceutical medicinal products. (wileyiran.com)
Hydrogel3
- We engineered a chitosan (CS)-based thermosensitive hydrogel to produce a VCM-nanoparticle (NPs)/Gel local drug delivery system. (dovepress.com)
- Fungal Carboxymethyl Chitosan-Impregnated Bacterial Cellulose Hydrogel as Wound-Dressing Agent. (bvsalud.org)
- Thermosensitive chitosan-gelatin-glycerol phosphate hydrogel as a controlled release system of ferulic acid for nucleus pulposus regeneration. (channel969.com)
Biomaterial1
- Thus, the acellular, chitosan-based biomaterial is a promising biopolymer composite for the treatment of chondral and osteochondral defects of traumatic character. (nurch.sk)
Hydrogels1
- We developed hydrogels by impregnating fungal-derived carboxymethyl chitosan to BC fiber networks using a simple solution immersion method . (bvsalud.org)
Biodegradable3
- 1) Are blended chitosan/PEG pastes biodegradable? (nih.gov)
- Chitosan, a non-toxic, biodegradable and biocompatible polysaccharide has attained great interest in pharmaceutical applications, as versatile drug delivery agent. (biomedcentral.com)
- Therefore, bioplastic films have been made from corn cellulose by adding sorbitol and chitosan as environmentally friendly plastic or biodegradable plastic. (ummi.ac.id)
Effect of chitosan1
- The effect of chitosan on macrophages has been extensively studied. (medscape.com)
Applications of Chitosan1
- Chitosan-Based Systems for Biopharmaceuticals is an important compendium of fundamental concepts, practical tools and applications of chitosan-based biopharmaceuticals for researchers in academia and industry working in drug formulation and delivery, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new materials development. (wileyiran.com)
Polysaccharide2
- Chitosan is a polysaccharide composed of D-glucosamine (2-amino-2-deoxy-β-D-glucose) and N -acetyl-D-glucosamine (2-acetamido-2-deoxy-β-D-glucose) (Figure 1 ). (biomedcentral.com)
- To further help with this, the researchers used chitosan, a polysaccharide found in crustacean shells, as a binder. (newenergyandfuel.com)
Carboxymethyl2
- Click the button below to add the Carboxymethyl chitosan 1g to your wish list. (p212121.com)
- Tension administration is also highly urged from companies that offer healthy and balanced cholesterol - all-natural different Carboxymethyl chitosan powder . (bamboo-parc.com)
Mesenchymal stem2
- The concept is a biphasic construct consisting of a porous, osteoconductive chitosan-calcium phosphate scaffold supporting a layer of neocartilage formed by marrow-derived mesenchymal stem cells. (openorthopaedicsjournal.com)
- Use of hybrid chitosan membranes and human mesenchymal stem cells from the Wharton jelly of umbilical cord for promoting nerve regeneration in an axonotmesis rat model. (bvsalud.org)
Vitro4
- Our blended paste/sponge formulations (0.5% acidic, 1% acidic, and acidic/neutral) along with a control neutral 1% chitosan sponge were tested in vitro for degradability, cytocompatibility, injectability tested by determining the amount of force needed to inject the pastes, elution of antibiotics, and activity tested using zone of inhibition studies. (nih.gov)
- An in vitro study was also performed to investigate the physical change of chitosan after treatment with artificial gastric and intestine juices. (researchgate.net)
- The in vitro study showed that chitosan became a gel in artificial gastric juice and its weight decreased by 15%, but there were no such physical changes when it was placed in artificial intestinal juice. (researchgate.net)
- Evaluar in vitro la modificación hidrofoba del esmalte como método preventivo en contra de la desmineralización. (bvsalud.org)
Biocompatible1
- Chitosan is a valuable material known for its antibacterial, anti-inflammatory, immune boosting, antioxidant and biocompatible properties. (trendlines.com)
Cationic2
- Chitosan is one of a few natural cationic polysaccharides. (medscape.com)
- It is clear that chitosan is a cationic macromolecular surfactant with special structure and properties. (pku.edu.cn)
Molecular Weight4
- The objective of the present experiment, therefore, was to clarify the effects of low-molecular-weight chitosan on the growth performance, incidence of diarrhea, intestinal morphology, barrier function, immune response, and antioxidant system in weaned piglets. (biomedcentral.com)
- The LC (molecular weight 20 to 30 kDa), which was obtained from chitosan by radiation pyrolysis technology, was offered by Jiaxing Korui Biotech Co., Ltd., Zhejiang, China. (biomedcentral.com)
- OBJECTIVE: To compare the efficacy of a 12-week treatment regimen with HEP-40TM low-molecular weight chitosan given at daily doses of 1,200 mg, 1,600 mg, and 2,400 mg in reducing serum low-density lipoprotein cholesterol (LDL-C) in patients with low-to-moderate hypercholesterolemia. (altmedrev.com)
- CONCLUSION: HEP-40 low-molecular weight chitosan, although not as effective as statins, is efficacious and safe in lowering LDL-C concentrations in treatment- naive patients with low-to-moderate hypercholesterolemia. (altmedrev.com)
Porous1
- In four experimental sheep, both defects were subsequently filled with the porous acellular polyhydroxybutyrate/chitosan (PHB/CHIT) - based implant. (nurch.sk)
Bacteria1
- When testing the antimicrobial activity of the complex against E. coli, Pseudomonas, Staphylococcus aureus and Bacillus cereus , the common food spoilage and pathogenic bacteria, Kanatt and co-workers report that the activity of CGC was similar to chitosan, with a minimum inhibition at concentrations of 0.05 per cent. (foodnavigator-usa.com)
Shellfish2
- Chitosan is a dietary fiber from shellfish. (medlineplus.gov)
- Today, chitosan extraction from shellfish involves chemical processes and large amounts of water, making it unsustainable. (trendlines.com)
Derivative6
- In experiment 1, the results showed that the immune response, such as Newcastle disease antibody and CD4 + T cells, would be significantly activated by feeding with chitosan and its derivative during 27 days. (medscape.com)
- However, the mortality of broilers was significantly decreased, while feed intake and weight gain of the birds were significantly increased in the group treated with chitosan and its derivative as compared with other groups. (medscape.com)
- Chitosan and its derivative have strong potential in immune enhancement and disease control, and can be used as a feed additive. (medscape.com)
- [ 5 ] This study was conducted to evaluate the concentration of the Newcastle disease (ND) antibody, CD3 + , CD4 + and CD8 + lymphoid cells, immune factors, diarrhea, respiratory symptoms and mortality of yellow-feathered broilers fed with chitosan and its derivative in water. (medscape.com)
- Levels of Newcastle disease antibody in broilers fed with chitosan derivative during 27, 30 and 35 days. (medscape.com)
- The aim of this work was to develop antifungal films from whey protein isolate (WPI) added with low quantities of a water soluble derivative of chitosan (WSCh), which was obtained through a Maillard reaction with glucosamine hydrochloride. (conicet.gov.ar)
Membrane3
- In this work, we developed an alginate/chitosan membrane sufficiently stable in a simulated vaginal fluid and able to dissolve over time at a very slow and linear rate. (dtu.dk)
- Metronidazole was effectively included in the alginate/chitosan membrane and its bactericide effect was demonstrated against Staphylococcus aureus and Gardnerella vaginalis, simultaneously showing good biocompatibility with a cervix epithelial cell line. (dtu.dk)
- Since this alginate/chitosan membrane is stable in a simulated vaginal environment, is easy to fabricate and can be used for the controlled release of a model drug, it represents a promising drug delivery system for local intravaginal applications. (dtu.dk)
FTIR2
- Fourier Transform Infrared Spectroscopy (FTIR) results showed that there was N-H bonding and O-H bonding in chitosan film. (unimap.edu.my)
- The strontium oxide-chitosan nanocomposites were characterized using Fourier transform infrared (FTIR), X-ray diffraction (XRD), and scanning electron microscope (SEM) techniques. (bvsalud.org)
Feces1
- In 3 studies, weight loss was not measured, but there was no evidence that chitosan blocked fat absorption from the intestines or fat excretion in the feces. (thecamreport.com)
Shells1
- Chitosan is a pulverized powder made from the shells of shrimp and crab. (thecamreport.com)
Composite3
- In the present study, the efficiency of chitosan-clay nano-composite coating on some quality propertiesof lemon was investigated during cold storage. (cigrjournal.org)
- Based on the results of present study, the quality properties of lemon fruit samples was improved after coating with chitosan-clay nano-composite during storage. (cigrjournal.org)
- To overcome such an issue, the researchers created an unique family of nano-crystalline metal oxyhydroxide-chitosan granular composite materials. (dcncorp.com)
Biomaterials1
- Insectta transforms food waste by returning it into the economy as valuable biomaterials (for example, chitosan) by utilizing the black soldier fly (hermetia illucens). (trendlines.com)
Conclusion1
- In conclusion, the study showed that gastro-retentive controlled release system prepared using chitosan could be a potential drug carrier of carvedilol with improved bioavailability. (simulations-plus.com)
Powder1
- Chitosan powder was dissolved in 2% of acetic acidand blended with ferredoxin. (unimap.edu.my)
Membranes1
- Zeolites including 3A, 4A, 5A, 13X, mordenite, and HZSM-5 were incorporated into chitosan (CS) matrix to fabricate the hybrid membranes for direct methanol fuel cell (DMFC). (harvard.edu)
Solubility3
- However, chitosan is restricted to be used in food and biomedical applications because of its difficult solubility and instability [ 10 ]. (biomedcentral.com)
- 5 kDa) are obtained from chitosan by physical, chemical or enzymatic methods, and have much higher solubility and stability than chitosan. (biomedcentral.com)
- The main constituent of LipoSan Ultra® is Chitosan, which has been modified and optimized to improve its binding, solubility and fat performance. (vivasaudavel.pt)
Toxicological1
- The fate and toxicological consideration related to chitosan, resulting with its interaction to ocular tissues, has also been summed up in addition. (eurekaselect.com)
Extract2
- The phytosynthesis of TiO 2 -NPswas promisingly achieved using an extract of pomegranate rind, whereas the fungal chitosan (FCt) was produced from Aspergillus brasiliensis biomass and was transformed to nanoform. (hindawi.com)
- Material and Methods: To obtain the chitosan spheres and the chitosan with crude ethanolic extract of mastruz (CEE) the Ionotropic gelation technique was used. (bvsalud.org)
Chemistry2
- Writing in the journal Food Chemistry , lead author Sweetie Kanatt from the Bhabha Atomic Research Centre in Mumbai report that by heating chitosan with glucose produces a chitosan-glucose complex (CGC) via the Maillard reaction, and this complex has excellent antioxidant and antimicrobial activity. (foodnavigator-usa.com)
- En: Starch: Chemistry and Technology. (rmiq.org)
Aqueous4
- A series of O-substituted alkylglyceryl chitosans with systematically varied alkyl chain length and degree of grafting has been employed for the formulation of aqueous nanoparticulate systems, which were in turn investigated for their effects on a modeled blood-brain-barrier system of mouse-brain endothelial cells. (port.ac.uk)
- Measurements of surface tension, conductivity, aggregation behavior and solubilization of pyrene of chitosan aqueous solutions have been carried out. (pku.edu.cn)
- Nevertheless, there is a lack of reports concerning complexing equilibria in aqueous solution, in particular when using the more advantageous microcrystalline form of chitosan (MCCh). (biomedcentral.com)
- A polymer of desired chemical properties is prepared by appropriate aggregation of the macromolecules from aqueous solutions of organic acids (via neutralization, coagulation and then precipitation of microcrystalline chitosan) [ 8 ]. (biomedcentral.com)
Formulation1
- Chitosan being a polycationic in nature interacts with the polyanionic surface of ocular mucosa through hydrogen bonding /ionic interactions and enhance the mucoadhesive effect of formulation. (eurekaselect.com)
Researchers1
- To make the cathode, the researchers spread a slurry of the nitrogen-doped carbon materials, chitosan binder, and elemental sulfur on aluminum foil and topped it with a net made of nanotubes to act as a final barrier to keep polysulfides from escaping. (newenergyandfuel.com)
Antimicrobial2
- The antimicrobial activity of the CGC was identical to that of chitosan against the common food spoilers and pathogens such as E. coli, Pseudomonas spp, S. aureus and B. cereus. (foodnavigator-usa.com)
- The authorization of the use of chitosan in oenology has opened the door to a new range of products with antimicrobial action. (infowine.com)
Fiber1
- LipoSan ULTRA® - high density of Chitosan, fiber that binds up to five times more to fat than conventional Chitosan. (vivasaudavel.pt)
Formulations1
- This review discussed various aspects related to chitosan and chitosan based formulations particularly developed for ocular therapeutics. (eurekaselect.com)
Ratio1
- The molar D-glucosamine to N -acetyl-D-glucosamine ratio in the chitosan sample is an estimate of the so called degree of deacetylation (DD). (biomedcentral.com)
Polymeric1
- [ 2 ] The chemical structure of chitosan is similar to that of cellulose, with polymeric 1,4-linked 2-amino-2-deoxy- D -glucose. (medscape.com)
Phosphate1
- Our goal is to create a bilayered construct which consists of an osteoconductive chitosan-calcium phosphate scaffold underlying a layer of neocartilage formed bymesenchymal stem cells (MSCs) through self-assembly. (openorthopaedicsjournal.com)
20201
- The global chitosan market is valued at USD 7 billion and is expected to expand at a CAGR of 25% between 2020 and 2030. (trendlines.com)
Serum3
- Chitosan is ineffective when serum-supplemented medium is used, suggesting that serum may contain a factor(s) that influences IgM production by lymphocytes. (medscape.com)
- Mean serum cholesterol went down 43% and mean serum hemoglobin increased from 5.8 to 6.8 g/dl in those patients who received the chitosan. (digitalnaturopath.com)
- 001 to 0.875 mM) levels in serum showed significant reductions after 12 weeks of chitosan treatment. (digitalnaturopath.com)
Biocompatibility2
- We blended chitosan/polyethylene glycol (PEG) pastes/sponges to increase biocompatibility and improve antibiotic coverage within the wound. (nih.gov)
- The preliminary studies demonstrated promising results for the blended chitosan/PEG pastes with antibiotics provided degradability, biocompatibility, injectability, and infection prevention for musculoskeletal-type wounds. (nih.gov)
Stomach2
- In addition, chitosan was found to be affected in the stomach and large intestine, but not in the small intestine. (researchgate.net)
- Chitosan has the unique ability to dissolve and bind to fats and cholesterol in the stomach . (digitalnaturopath.com)
Glucose2
- The Maillard reaction product of chitosan and glucose extended the shelf-life of lamb in laboratory tests by two weeks, and may offer industry with a novel and efficient preservative for meat products. (foodnavigator-usa.com)
- From the present studies that the chitosan-glucose complex (CGC) is a better preservative than chitosan alone. (foodnavigator-usa.com)
Absorption1
- 2002: Chitosan supplements failed to increase fecal fat content and therefore did not block fat absorption. (thecamreport.com)
Clinical1
- Weight loss was the most dramatic result from a Helsinki Chitosan clinical pilot study. (digitalnaturopath.com)
Controlled Release1
- The objective of present investigation was to develop gastro-retentive controlled release system of carvedilol using biological macromolecule, chitosan. (simulations-plus.com)
Results6
- Most study results dispute the claim that chitosan is a "fat blocker. (thecamreport.com)
- More importantly, the best results occurred when chitosan was combined with support from other dieters and healthcare professionals. (thecamreport.com)
- Scanning Electron Microscope (SEM) results showed that the surface of chitosan-ferredoxin film is smoother and more compact than chitosan film. (unimap.edu.my)
- The results show that chitosan is surface-active, and can aggregate in single molecule, or critical aggregation number cac≈ 0. (pku.edu.cn)
- In addition to developing a new source of sustainable chitosan for the industry, Insectta's proprietary extraction process also results in a purer, cleaner, and higher-grade chitosan as compared to traditional sources. (trendlines.com)
- All the results confirmed the formation of chitosan-strontium oxide nanocomposite. (bvsalud.org)