Alphavirus Infections
Reunion
One of the Indian Ocean Islands, east of Madagascar. Its capital is Saint-Denis. It was discovered in 1507 by the Portuguese and claimed by France in 1638. It was first colonized in 1662 as Isle de Bourbon but renamed Reunion in 1793. In 1946 it was made an overseas department of France. The name commemorates the reunion of the revolutionaries from Marseilles with the National Guard in Paris in 1792. (From Webster's New Geographical Dictionary, 1988, p1011; Room, Brewer's Dictionary of Names, 1992, p454; French Embassy)
Aedes
Indian Ocean Islands
Numerous islands in the Indian Ocean situated east of Madagascar, north to the Arabian Sea and east to Sri Lanka. Included are COMOROS (republic), MADAGASCAR (republic), Maldives (republic), MAURITIUS (parliamentary democracy), Pemba (administered by Tanzania), REUNION (a department of France), and SEYCHELLES (republic).
Comoros
A group of Indian Ocean Islands, the islands of Great Comoro, Anjouan, Mayotte, and Moheli, lying between northeast Mozambique and northwest Madagascar. The capital is Moroni. In 1914 they became a colony attached to Madagascar administratively and were made a French overseas territory in 1947. Except for Mayotte which remained French, Comoros became an independent republic in 1975. Comoros represents the Arabic qamar, moon, said by some scholars to be linked with the mystical Mountains of the Moon said to be somewhere in equatorial Africa. (From Webster's New Geographical Dictionary, 1988, p283 & Room, Brewer's Dictionary of Names, 1992, p122)
Disease Outbreaks
Insect Vectors
Alphavirus
Indian Ocean
A body of water covering approximately one-fifth of the total ocean area of the earth, extending amidst Africa in the west, Australia in the east, Asia in the north, and Antarctica in the south. Including the Red Sea and the Persian Gulf, it constitutes the third largest ocean after the ATLANTIC OCEAN and the PACIFIC OCEAN. (New Encyclopaedia Britannica Micropaedia, 15th ed, 1990, p289)
Ross River virus
Culicidae
Africa, Central
Communicable Diseases, Emerging
Africa, Eastern
Arboviruses
Arthropod-borne viruses. A non-taxonomic designation for viruses that can replicate in both vertebrate hosts and arthropod vectors. Included are some members of the following families: ARENAVIRIDAE; BUNYAVIRIDAE; REOVIRIDAE; TOGAVIRIDAE; and FLAVIVIRIDAE. (From Dictionary of Microbiology and Molecular Biology, 2nd ed)
Virus Replication
Dengue
Sindbis Virus
The type species of ALPHAVIRUS normally transmitted to birds by CULEX mosquitoes in Egypt, South Africa, India, Malaya, the Philippines, and Australia. It may be associated with fever in humans. Serotypes (differing by less than 17% in nucleotide sequence) include Babanki, Kyzylagach, and Ockelbo viruses.
Vero Cells
Malaysia
A parliamentary democracy with a constitutional monarch in southeast Asia, consisting of 11 states (West Malaysia) on the Malay Peninsula and two states (East Malaysia) on the island of BORNEO. It is also called the Federation of Malaysia. Its capital is Kuala Lumpur. Before 1963 it was the Union of Malaya. It reorganized in 1948 as the Federation of Malaya, becoming independent from British Malaya in 1957 and becoming Malaysia in 1963 as a federation of Malaya, Sabah, Sarawak, and Singapore (which seceded in 1965). The form Malay- probably derives from the Tamil malay, mountain, with reference to its geography. (From Webster's New Geographical Dictionary, 1988, p715 & Room, Brewer's Dictionary of Names, 1992, p329)
Viral Vaccines
Dengue Virus
Angola
Antibodies, Neutralizing
Cercopithecus aethiops
Vaccinia virus
Gabon
Disease Vectors
Host Specificity
Immunoglobulin M
PubMed
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Virology
Air Conditioning
The maintenance of certain aspects of the environment within a defined space to facilitate the function of that space; aspects controlled include air temperature and motion, radiant heat level, moisture, and concentration of pollutants such as dust, microorganisms, and gases. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Epidemics
Photography
Vectors of Chikungunya virus in Senegal: current data and transmission cycles. (1/380)
Chikungunya fever is a viral disease transmitted to human beings by Aedes genus mosquitoes. From 1972 to 1986 in Kedougou, Senegal, 178 Chikungunya virus strains were isolated from gallery forest mosquitoes, with most of them isolated from Ae. furcifer-taylori (129 strains), Ae. luteocephalus (27 strains), and Ae. dalzieli (12 strains). The characteristics of the sylvatic transmission cycle are a circulation periodicity with silent intervals that last approximately three years. Few epidemics of this disease have been reported in Senegal. The most recent one occurred in 1996 in Kaffrine where two Chikungunya virus strains were isolated from Ae. aegypti. The retrospective analysis of viral isolates from mosquitoes, wild vertebrates, and humans allowed to us to characterize Chikungunya virus transmission cycles in Senegal and to compare them with those of yellow fever virus. (+info)Comparison of PanBio dengue duo enzyme-linked immunosorbent assay (ELISA) and MRL dengue fever virus immunoglobulin M capture ELISA for diagnosis of dengue virus infections in Southeast Asia. (2/380)
The performances of the MRL dengue fever virus immunoglobulin M (IgM) capture enzyme-linked immunosorbent assay (ELISA) and the PanBio Dengue Duo IgM capture and IgG capture ELISA were compared. Eighty sera from patients with dengue virus infections, 24 sera from patients with Japanese encephalitis (JE), and 78 sera from patients with nonflavivirus infections, such as malaria, typhoid, leptospirosis, and scrub typhus, were used. The MRL test showed superior sensitivity for dengue virus infections (94 versus 89%), while the PanBio test showed superior specificity for JE (79 versus 25%) and other infections (100 versus 91%). The PanBio ELISA showed better overall performance, as assessed by the sum of sensitivity and specificity (F value). When dengue virus and nonflavivirus infections were compared, F values of 189 and 185 were obtained for the PanBio and MRL tests, respectively, while when dengue virus infections and JE were compared, F values of 168 and 119 were obtained. The results obtained with individual sera in the PanBio and MRL IgM ELISAs showed good correlation, but this analysis revealed that the cutoff value of the MRL test was set well below that of the PanBio test. Comparing the sensitivity and specificity of the tests at different cutoff values (receiver-operator analysis) revealed that the MRL and PanBio IgM ELISAs performed similarly in distinguishing dengue virus from nonflavivirus infections, although the PanBio IgM ELISA showed significantly better distinction between dengue virus infections and JE. The implications of these findings for the laboratory diagnosis of dengue are discussed. (+info)Re-emergence of Chikungunya and O'nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships. (3/380)
Chikungunya (CHIK) virus is a member of the genus Alphavirus in the family TOGAVIRIDAE: Serologically, it is most closely related to o'nyong-nyong (ONN) virus and is a member of the Semliki Forest antigenic complex. CHIK virus is believed to be enzootic throughout much of Africa and historical evidence indicates that it spread to other parts of the world from this origin. Strains from Africa and Asia are reported to differ biologically, indicating that distinct lineages may exist. To examine the relatedness of CHIK and ONN viruses using genetic data, we conducted phylogenetic studies on isolates obtained throughout Africa and Southeast Asia. Analyses revealed that ONN virus is indeed distinct from CHIK viruses, and these viruses probably diverged thousands of years ago. Two distinct CHIK virus lineages were delineated, one containing all isolates from western Africa and the second comprising all southern and East African strains, as well as isolates from Asia. Phylogenetic trees corroborated historical evidence that CHIK virus originated in Africa and subsequently was introduced into Asia. Within the eastern Africa and southern Africa/Asia lineage, Asian strains grouped together in a genotype distinct from the African groups. These different geographical genotypes exhibit differences in their transmission cycles: in Asia, the virus appears to be maintained in an urban cycle with Aedes aegypti mosquito vectors, while CHIK virus transmission in Africa involves a sylvatic cycle, primarily with AE: furcifer and AE: africanus mosquitoes. (+info)Phase II safety and immunogenicity study of live chikungunya virus vaccine TSI-GSD-218. (4/380)
We conducted a phase II, randomized, double-blind, placebo-controlled, safety and immunogenicity study of a serially passaged, plaque-purified live chikungunya (CHIK) vaccine in 73 healthy adult volunteers. Fifty-nine volunteers were immunized one time subcutaneously with the CHIK vaccine and 14 were immunized with placebo (tissue culture fluid). Vaccinees were clinically evaluated intensively for one month, and had repeated blood draws for serological assays (50% plaque-reduction neutralization test) for one year. Except for transient arthralgia in five CHIK vaccinees, the number and severity of local and systemic reactions and abnormal laboratory tests after immunization were similar in CHIK vaccinees and placebo recipients. Fifty-seven (98%) of 58 evaluable CHIK vaccinees developed CHIK neutralizing antibody by day 28, and 85% of vaccinees remained seropositive at one year after immunization. No placebo recipients seroconverted. This promising live vaccine was safe, produced well-tolerated side effects, and was highly immunogenic. (+info)Complete nucleotide sequence of chikungunya virus and evidence for an internal polyadenylation site. (5/380)
In this study, the complete genomic sequence of chikungunya virus (CHIK; S27 African prototype) was determined and the presence of an internal polyadenylation [I-poly(A)] site was confirmed within the 3' non-translated region (NTR) of this strain. The complete genome was 11805 nucleotides in length, excluding the 5' cap nucleotide, an I-poly(A) tract and the 3' poly(A) tail. It comprised two long open reading frames that encoded the non-structural (2474 amino acids) and structural polyproteins (1244 amino acids). The genetic location of the non-structural and structural proteins was predicted by comparing the deduced amino acid sequences with the known cleavage sites of other alphaviruses, located at the C-terminal region of their virus-encoded proteins. In addition, predicted secondary structures were identified within the 5' NTR and repeated sequence elements (RSEs) within the 3' NTR. Amino acid sequence homologies, phylogenetic analysis of non-structural and structural proteins and characteristic RSEs revealed that although CHIK is closely related to o'nyong-nyong virus, it is in fact a distinct virus. The existence of I-poly(A) fragments with different lengths (e.g. 19, 36, 43, 91, 94 and 106 adenine nucleotides) at identical initiation positions for each clone strongly suggests that the polymerase of the alphaviruses has a capacity to create poly(A) by a template-dependant mechanism such as 'polymerase slippage', as has been reported for vesicular stomatitis virus. (+info)Effect of temperature stress on immature stages and susceptibility of Aedes aegypti mosquitoes to chikungunya virus. (6/380)
A high temperature stress of 44.5 degrees C for 10 minutes on the larval stages was found to affect the susceptibility of adult Aedes aegypti mosquitoes to chikungunya virus. At this temperature, the mortality of the mosquito larvae was found to be approximately 95%, whereas a temperature greater than 45 degrees C for 10 minutes was found to be lethal. A temperature tolerant (TT) strain was developed by exposing the larvae to a temperature of 44.5 degrees C for 10 minutes at every generation for five generations. This strain was established to determine whether increase in the susceptibility was due to any selection pressure of higher temperature or to the influence of other intrinsic factors such as expression of immunoresponsive (IR) genes. Other studies on these mosquito strains showed that when maintained at 28 +/- 1 degrees C, there was no difference in the larval duration and mortality in the immature stages, but the mean survival of female mosquitoes in the TT strain was 5-6 days longer. Conversely, when mosquitoes were maintained throughout at 37 degrees C the mean survival of the mosquitoes decreased drastically in both strains, but the mean survival of females in the TT strain was 5-6 days longer compared with the unstressed controls. This increases the probability of at least one more blood meal. Fecundity of the TT strain was found to be lower than that of the control mosquitoes. Data suggest that expression of certain IR genes was affected by the heat shock. Some of these genes were up-regulated and down-regulated, which may have affected the susceptibility of mosquitoes to the virus. Although there was some selection in the temperature-tolerant individuals in the TT strain, when stressed by heat they showed expression of IR genes in a pattern similar to that in the normal controls. It appears that an increase in temperature above the average temperature of an area might help increase the proportion of virus-susceptible mosquitoes in the population. Such an increase in temperature in an endemic area would not only enhance the selection of temperature-tolerant individuals in a population having more longevity, but would also affect both intrinsic and extrinsic factors by reducing the extrinsic incubation period and increasing susceptibility of mosquitoes to viruses due to affected expression of IR genes. (+info)Differential infectivities of o'nyong-nyong and chikungunya virus isolates in Anopheles gambiae and Aedes aegypti mosquitoes. (7/380)
O'nyong-nyong virus (ONNV) and chikungunya virus (CHIKV) are closely related alphaviruses that cause human disease in Africa and Asia. Like most alphaviruses, CHIKV is vectored by culicine mosquitoes. ONNV is considered unusual as it primarily infects anopheline mosquitoes; however, there are relatively few experimental data to support this. In this study, three strains of ONNV and one strain of CHIKV were evaluated in Anopheles gambiae and Aedes aegypti mosquitoes and in four cell lines. As predicted, CHIKV was not infectious to An. gambiae, and we observed strain-variability for ONNV with respect to the ability of the virus to infect An. gambiae and Ae. aegypti. The species specificity in vivo was reflected by in vitro experiments using culicine and anopheline-derived cell lines. (+info)Determinants of vector specificity of o'nyong nyong and chikungunya viruses in Anopheles and Aedes mosquitoes. (8/380)
The alphaviruses o'nyong nyong virus (ONNV) and chikungunya virus (CHIKV) provide a unique system to study the viral genes involved in vector specificity. ONNV infects both anopheline and culicine mosquitoes, whereas CHIKV infects only culicine mosquitoes. In this study, chimeric viruses were constructed that contained genes from both ONNV and CHIKV. These chimeras and previously described full-length infectious clones of ONNV and CHIKV were evaluated in Anopheles gambiae and Aedes aegypti mosquitoes. Virus derived from the infectious clones of ONNV and CHIKV retained the vector specificity of the parental viruses. All six of the chimeras were found to infect Ae. aegypti mosquitoes at high rates but only the chimera containing viral genes encoding all of the structural proteins of ONNV was able to infect An. gambiae mosquitoes. These data indicate that all of the viral structural proteins are necessary for ONNV to infect An. gambiae mosquitoes. (+info)
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Rheumatoid arthritis after Chikungunya fever: a prospective follow-up study of 21 cases | Annals of the Rheumatic Diseases
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The American Journal of Tropical Medicine and Hygiene | Chikungunya Virus Infection and Transmission in Five Species of...
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ToxExpo 2021
Antibody Based Therapeuticcs for Chikungunya Virus - Michael Diamond
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Diseases Caused By Mosquitoes: Mosquito Bite Diseases- Odomos
Ebola virus disease
The four are Bundibugyo virus (BDBV), Sudan virus (SUDV), Taï Forest virus (TAFV) and one simply called Ebola virus (EBOV, ... The virus responsible for the initial outbreak, first thought to be Marburg virus, was later identified as a new type of virus ... Main articles: Ebola virus cases in the United States, Ebola virus disease in Spain, and Ebola virus disease in the United ... Virus taxonomy classification and nomenclature of viruses; 8th report of the International Committee on Taxonomy of Viruses. ...
Neglected tropical diseases
The virus was first isolated from an outbreak in Tanzania in 1952. Chikungunya virus is a member of the genus Alphavirus and ... Chikungunya virus , CDC". www.cdc.gov. 17 December 2018. Retrieved 17 March 2020. Chikungunya, WHO, archived from the original ... viruses (dengue and chikungunya, rabies).[citation needed] The World Health Organization recognizes the twenty diseases below ... The word chikungunya is from the Makonde which means "that which bends up", and this refers to the effect of the debilitating ...
Silvestrol
Henss L, Scholz T, Grünweller A, Schnierle BS (October 2018). "Silvestrol Inhibits Chikungunya Virus Replication". Viruses. 10 ... Elgner F, Sabino C, Basic M, Ploen D, Grünweller A, Hildt E (March 2018). "Inhibition of Zika Virus Replication by Silvestrol ... January 2017). "The natural compound silvestrol is a potent inhibitor of Ebola virus replication". Antiviral Research. 137: 76- ... ". Viruses. 10 (4): 149. doi:10.3390/v10040149. PMC 5923443. PMID 29584632. Müller C, Schulte FW, Lange-Grünweller K, Obermann ...
Edward McSweegan
There, he reported on a number of pathogens, including Zika, chikungunya, and Hepatitis C. He worked at the Global Virus ... "Global Virus Network Staff". Global Virus Network. Archived from the original on 2015-03-15. Retrieved 6 September 2020. ... McSweegan, E; Weaver, SC; Lecuit, M; Frieman, M; Morrison, TE; Hrynkow, S (August 2015). "The Global Virus Network: Challenging ... Mcsweegan was detailed by the NIH to the Global Virus Network, where he became a program manager. ...
Reverse zoonosis
Yellow fever viruses, Dengue fever viruses, and Zika viruses are of the Flavivirus genera and Chikungunya virus is of the ... Chikungunya: The Chikungunya virus is a single stranded RNA alphavirus typically transmitted by the Aedes mosquitoes to another ... The animal reservoir of the virus maintains a suitable virus level in the blood to allow the infection of a vector mosquito. A ... Tsetsarkin, Konstantin A; Chen, Rubing; Weaver, Scott C (February 2016). "Interspecies transmission and chikungunya virus ...
Priority review
Chikungunya virus disease (added in 2018 final order). *Cryptococcal meningitis (added in 2018 final order) ... Extension to ebola virus[edit]. In December 2014, the Senate approved a bill that would add the Ebola virus to the Priority ... Zika virus disease (added in 2016 by Pub. L. 114-146). *Any other infectious disease for which there is no significant market ... The Ebola virus is a type of Filovirus. According to the Congressional Budget Office, enactment of the law does not have an ...
Sabin Vaccine Institute
CS1 maint: discouraged parameter (link) Dipali Pathak (30 August 2016). "Grant to develop chikungunya virus vaccine awarded". ... CS1 maint: discouraged parameter (link) "Sabin Institute To Develop GSK's Ebola and Marburg Virus Vaccines". www. ... "Sabin Institute To Develop GSK's Ebola and Marburg Virus Vaccines". www.precisionvaccinations.com. Retrieved 2020-05-20. Miller ...
List of epidemics
Chikungunya outbreaks Chikungunya virus [85]. , 50 Pakistan 2006 2006 dengue outbreak in Pakistan dengue fever [86]. ... 2015-16 Zika virus epidemic Zika virus. Hundreds (as of 1 April 2016[update]) Africa 2016 2016 yellow fever outbreak in Angola ... 2013-14 chikungunya outbreak Chikungunya [114]. 40 Madagascar 2014-present 2014 Madagascar plague outbreak Bubonic plague [115] ... 2018 Nipah virus outbreak Nipah virus infection 1,743 (as of 21 July 2019[update]) Democratic Republic of the Congo & Uganda ...
Pathogen
... and rubella viruses and the influenza virus.[30] Some viruses such as HIV, dengue, and chikungunya do not have vaccines ... Examples of viruses that undergo this process are herpes simplex virus, human immunodeficiency virus, and vaccinia virus.[44] ... VirusesEdit. Main article: Virus. Viruses are small particles, typically between 20 and 300 nanometers in length,[15] ... "Symptoms, Diagnosis, & Treatment , Chikungunya virus , CDC". www.cdc.gov. 2018-12-17. Retrieved 2019-11-06.. ...
Prohibitin
Human prohibitin 1 has some activity as a virus receptor protein, having been identified as a receptor for Chikungunya Virus ( ... "Identification of prohibitin as a Chikungunya virus receptor protein". Journal of Medical Virology. 84 (11): 1757-70. doi: ... CHIKV) and Dengue Virus 2 (DENV-2). Little else is known about the activity of the prohibitins in viral pathogenesis. ...
Sonja Buckley
"Isolation of chikungunya virus contaminating an Aedes albopictus cell line." Journal of General Virology 27.1 (1975): 97-100. ... Her first research "assignment was to study the spread of the polio virus in East Baltimore neighborhoods". After working as a ... "Lassa fever, a new virus disease of man from West Africa." The American journal of tropical medicine and hygiene 19.4 (1970): ... She was the first person to culture Lassa virus, the causative agent of Lassa fever, a potentially deadly disease that ...
Malir District
"Aedes aegypti mosquito responsible for Chikungunya virus in Karachi: report". Dunya News tv. 21 December 2016. Retrieved 21 ... as thousands of patients were affected by mysterious Chikungunya virus in December, 2016. Despite joint denial by WHO and ... Provincial Government of Sindh discloses that aedes aegypti mosquito is responsible for spreading Chikungunya in the area. The ... "More patients arrive at Karachi hospital with symptoms of mysterious virus". Geo News tv. Retrieved 21 December 2016. " ...
Multiomics
"Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases". Molecular Systems Biology. 14 (8): ... Shoaib; Monga, Isha; Dar, Showkat Ahmad; Singh, Sandeep (2016-09-16). "ZikaVR: An Integrated Zika Virus Resource for Genomics, ... such as pediatric chikungunya, as well as noncommunicable autoimmune diseases. Integrative omics has also been employed ... a multiomic resource for Zika virus data Ecomics, a normalized multi-omic database for Escherichia coli data, GourdBase, ...
Makonde language
"Four cases of acute flaccid paralysis associated with chikungunya virus infection". Epidemiol Infect. 136 (9): 1277-80. doi: ... New Updated Guthrie List Online Morens DM and Fauci AS (2014). "Chikungunya at the Door - Déjà Vu All Over Again?". New England ... Chikungunya', which is derived from the Makonde root verb kungunyala (meaning "that which bends up", "to become contorted," or ...
Andrew Kasarskis
"Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases". Molecular Systems Biology. 14 (8): ...
Chandrakant Lahariya
Lahariya, C; Pradhan, SK (December 2006). "Emergence of chikungunya virus in Indian subcontinent after 32 years: A review". ...
Emergent BioSolutions
Another is focused on the chikungunya virus which is transmitted by mosquitoes. The transaction provides Emergent with a Swiss ... As of the end of June 2016, 60 countries and territories had reported transmission of the Zika virus from mosquitoes. Emergent ... the virus which causes COVID-19. Human testing began in 2020, and the vaccine received Emergency Use Authorization from the FDA ... could become the first company to develop a vaccine for the virus. Emergent spun off its biosciences division in August 2016, ...
Neglected tropical diseases in India
"Emergence of chikungunya virus in Indian subcontinent after 32 years: A review". Journal of Vector Borne Diseases. 43 (4): 151- ... The WHO groups dengue and chikungunya fever together, but these are separate conditions. India had chikungunya cases before ... "The resurgence of chikungunya in India". Ideas for India - Evidence based policy. Sudarshan, M.K.; Madhusudana, S.N.; Mahendra ... Muniaraj, M (March 2014). "Fading chikungunya fever from India: beginning of the end of another episode?". The Indian Journal ...
Aedes albopictus
albopictus is known to transmit pathogens and viruses, such as the yellow fever virus, dengue fever, Chikungunya fever, and ... The Asian tiger mosquito was also the transmitter of the virus in the first and only outbreak of Chikungunya fever on the ... Evidently, mutated strains of the Chikungunya virus are being directly transmitted through Ae. albopictus particularly well and ... Tsetsarkin, KA; Vanlandingham, DL; McGee, CE; Higgs, S (2007). "A Single Mutation in Chikungunya Virus Affects Vector ...
Mosquito-borne disease
Examples are the Zika virus, chikungunya virus, yellow fever and dengue fever. The re-emergence of the viruses has been at a ... Flaviviridae viruses transmissible via vectors like mosquitoes include West Nile virus and yellow fever virus, which are single ... Laboratory blood tests can identify evidence of chikungunya or other similar viruses such as dengue and Zika. Blood test may ... "Testing for Zika Virus". CDC. 2017-08-30. Retrieved 2017-10-01. "Chikungunya". World Health Organization. Retrieved 2017-10-01 ...
Microcephaly
"Perinatal Chikungunya Virus-Associated Encephalitis Leading to Postnatal-Onset Microcephaly and Optic Atrophy". The Pediatric ... In addition, viruses such as cytomegalovirus (CMV) or Zika have been shown to infect and kill the primary stem cell of the ... Li, C; Xu, D; Ye, Q; Hong, S; Jiang, Y; Liu, X; Zhang, N; Shi, L; Qin, CF; Xu, Z (7 July 2016). "Zika Virus Disrupts Neural ... A study published in The New England Journal of Medicine has documented a case in which they found evidence of the Zika virus ...
ChAdOx1
"Assessment of Immunogenicity and Neutralisation Efficacy of Viral-Vectored Vaccines Against Chikungunya Virus". Viruses. 11 (4 ... There are also investigation lines that use the vector for vaccines against the Zika virus (ChAdOx1 ZIKV) and the Chikungunya ... virus (ChAdOx1 sCHIKV). The ChAdOx1 vector has been used as a platform for a vaccine against coronavirus disease since the ...
Pravindra Kumar
Sharma, Rajesh; Kesari, Pooja; Kumar, Pravindra; Tomar, Shailly (2018). "Structure-function insights into chikungunya virus ... "Crystal structure of chikungunya virus nsP2 cysteine protease reveals a putative flexible loop blocking its active site". ... Chikungunya Bacillus subtilis India portal Physics portal Chemistry portal Medicine portal Please see Selected bibliography ...
Gary Nabel
A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection. Nat. Med. 16(3):334- ... Nabel discovered the first effective vaccine candidates for Ebola, Chikungunya and encephalitis viruses through his approach to ... He developed the first Chikungunya virus vaccine effective in primates and advanced universal influenza vaccines of ... Chikungunya, and Epstein-Barr virus. He led research on viral molecular biology, protein structure, and immunotherapy, which ...
Health in Bangladesh
Here is the Clinical features of Chikungunya virus infections compared with dengue virus infections. Diagnosis Several methods ... Dengue and Chikungunya. Chikungunya Chikungunya is one of the neglected tropical diseases of Bangladesh. It is a viral disease ... In the South-East Asia region, Chikungunya virus is maintained in the human population by a human-mosquito-human transmission ... Treatment There is no vaccine to prevent or anti-viral drugs to treat Chikungunya virus. Treatment is directed primarily at ...
Dengue fever outbreaks
Polynesia experienced an 'unprecedented' series of outbreaks (14), along with Chikungunya and Zika virus. In only 7 weeks, in ... therefore their infections may also be due to chikungunya, a coinfection of both, or even other similar viruses. The first ... American visitors to and visitors from dengue-endemic regions will continue to present a potential pathway for the dengue virus ... Relation of disease severity to antibody response and virus recovered". The Yale Journal of Biology and Medicine. 42 (5): 311- ...
Aedes hensilli
"Aedes hensilli as a Potential Vector of Chikungunya and Zika Viruses". PLoS Neglected Tropical Diseases. pp. e3188. doi:10.1371 ... hensilli is a potential vector of dengue virus and Zika virus and laboratory studies have indicated that it could play a role ... Fritz, C L; Savage, H M; Yolwa, A; Gubler, D J; Vorndam, V; Rutstein, D (1 April 1998). "Epidemic of dengue-4 virus in Yap ...
Zika fever
"Help Control Mosquitoes that Spread Dengue, Chikungunya, and Zika Viruses" (PDF). Chikungunya Virus Home: Fact Sheets and ... "Zika Virus". CDC. 5 November 2014. Retrieved 20 June 2019. "Symptoms, Diagnosis, & Treatment of Zika Virus". Zika Virus Home. ... Zika virus has been isolated from semen samples, with one person having 100,000 times more virus in semen than blood or urine, ... Zika virus is a mosquito-borne flavivirus closely related to the dengue and yellow fever viruses. While mosquitoes are the ...
Anguilla women's national football team
Anguilla withdrew before the start of the competition due to the outbreak of Chikungunya virus. This means that Anguilla's last ...
Virus-Taxonomie
Genus Alphavirus, mit Species Chikungunya-Virus (CHIKV), Mayaro-Virus (MAYV), Ross-River-Virus (RRV), sowie Sindbis-Virus (SINV ... Usutu-Virus - en. Usutu virus (USUV), Zika-Virus - en. Zika virus (ZIKV), sowie Gelbfieber-Virus - en. Yellow fever virus (YFV) ... Genus ‚Negevirus', mit Species ‚Blackford virus', ‚Bofa virus', ‚Buckhurst virus', ‚Marsac virus', sowie ‚Muthill virus'[53] ... Sorghum mosaic virus (SrMV), Lily-Mottle-Virus - en. Lily mottle virus (LMoV), sowie Sellerie-Virus Y - en. Apium virus Y (ApVY ...
Lassa fever
Lujo virus. References[edit]. *^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad "Lassa fever". WHO. March 2016 ... Confirmation is by laboratory testing to detect the virus's RNA, antibodies for the virus, or the virus itself in cell culture. ... The Lassa virus is one of several viruses identified by WHO as a likely cause of a future epidemic. They therefore list it for ... Lassa virus is a member of the Arenavirida family of viruses.[7] Specifically it is an old world arenavirus, which is enveloped ...
Antonine Plague
"Origin of measles virus: divergence from rinderpest virus between the 11th and 12th centuries.", Virol. J., 7 (52). ... Chikungunya outbreaks (2006). *Pakistani dengue (2006). *Iraqi cholera (2007). *Zimbabwean cholera (2008-2009) ... "Origin of the Measles Virus: Divergence from Rinderpest Virus Between the 11th and 12th Centuries". Virology. 7: 52-55. doi ...
Yellow fever
"Impact of Wolbachia on Infection with Chikungunya and Yellow Fever Viruses in the Mosquito Vector Aedes aegypti". PLOS ... Other viral hemorrhagic fevers, such as Ebola virus, Lassa virus, Marburg virus, and Junin virus, must be excluded as the cause ... Viruses reach the stomach of the mosquito, and if the virus concentration is high enough, the virions can infect epithelial ... Yellow fever is caused by yellow fever virus, a 40- to 50-nm-wide enveloped RNA virus, the type species and namesake of the ...
Artificial induction of immunity
Anthrax is now known to be caused by a bacterium, and rabies is known to be caused by a virus. The microscopes of the time ... a virus, or a prion. At present, the science to understand this process is available but not the technology to perform it.[25] ... could reasonably be expected to show bacteria, but imaging of viruses had to wait until the development of electron microscopes ...
டெங்குக் காய்ச்சல் - தமிழ் விக்கிப்பீடியா
2.0 2.1 2.2 2.3 Chen LH, Wilson ME (October 2010). "Dengue and chikungunya infections in travelers". Curr. Opin. Infect. Dis. ... 4.0 4.1 Rodenhuis-Zybert IA, Wilschut J, Smit JM (August 2010). "Dengue virus life cycle: viral and host factors modulating ... "Dengue virus pathogenesis: an integrated view". Clin. Microbiol. Rev. 22 (4): 564-81. doi:10.1128/CMR.00035-09. பப்மெட் ... arthropod-borne viruses) ஆர்போ எனும் பெயர்கொண்டும் அழைக்கப்படுகின்றன.[3] ...
Chikungunya
... is an infection caused by the chikungunya virus (CHIKV).[3] Symptoms include fever and joint pains.[2] These ... Chikungunya virus is passed to humans when a bite from an infected mosquito breaks the skin and introduces the virus into the ... Chikungunya virus (CHIKV), is a member of the genus Alphavirus, and family Togaviridae. It was first isolated in 1953 in ... to those exposed to a high risk of chikungunya infection. No antiviral treatment for Chikungunya virus is currently available, ...
Category:Low-importance virus articles
Talk:2013-14 chikungunya outbreak. *Talk:2013-2014 Zika virus outbreaks in Oceania ... Pages in category "Low-importance virus articles". The following 200 pages are in this category, out of approximately 1,493 ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Category:Low-importance_virus_articles&oldid=388350164" ...
Respiratory syncytial virus vaccine
A respiratory syncytial virus vaccine (RSV vaccine) is a vaccine which prevents infection by respiratory syncytial virus. No ... Mejias, Asuncion; Rodriguez-Fernandez, Rosa; Peeples, Mark E.; Ramilo, Octavio (October 2019). "Respiratory Syncytial Virus ... "Respiratory syncytial virus vaccines". Clinical Microbiology Reviews. 11 (3): 430-9. doi:10.1128/CMR.11.3.430. PMC 88889. PMID ... "The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates" (PDF). The Lancet ...
आइसीडी-१० अध्याय ब - विकिपीडिया
A92.0) Chikungunya virus disease. *(A92.1) O'nyong-nyong fever. *(A92.2) Venezuelan equine fever ... B20-B24) Human immunodeficiency virus (HIV) disease[संपादित करें]. *(B20.) Human Immunodeficiency Virus (HIV) disease Resulting ... B24.) Unspecified Human Immunodeficiency Virus (HIV) Disease. (B25-B34) Other viral diseases[संपादित करें]. *(B25.) ... B21.) Human Immunodeficiency Virus (HIV) disease Resulting in malignant neoplasms *(B21.0) HIV disease resulting in Kaposi's ...
Immunologic adjuvant
There are many adjuvants, some of which are inorganic (such as alum), that also carry the potential to augment immunogenicity.[7][8] Two common salts include aluminium phosphate and aluminium hydroxide. Aluminium salts are the most commonly-used adjuvants in human vaccines. Their adjuvant activity was described in 1926.[9] The precise mechanism of alum action remains unclear but some insights have been gained. For instance, alum can trigger dendritic cells (DC) and other immune cells to secrete interleukin-1β (IL-1β), an immune signal that promotes antibody production. Alum adheres to the cell's plasma membrane and rearranges certain lipids there. Spurred into action, the DC picks up the antigen and speeds to a lymph node, where it sticks tightly to a helper T cell and presumably induces an immune response. A second mechanism depends on alum killing immune cells at the injection site although researchers aren't sure exactly how alum kills these cells. It has been speculated that the dying ...
Rotavirus vaccine
The fifth reassortant virus expresses the attachment protein VP4, (type P1A), from the human rotavirus parent strain and the ... Rotavirus antigens for parenteral delivery, such as the P2-VP8 candidate, can be expressed as virus-like particles prepared in ... Both are taken orally and contain disabled live virus. ... and killed virus. These novel approaches are being pursued ...
Hepatocyte growth factor
HGF may further play a role as an indicator for prognosis of chronicity for Chikungunya virus induced arthralgia. High HGF ... "Persistent arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony ...
එන්නත් - විකිපීඩියා
කුඩා ළමුන්ගේ ප්රතිශක්තිකරණ පද්ධතිය එන්නත් කිරීමකින් පසුව ඒ සදහා ප්රතිශක්තිකරණ ක්රියාවලීන් ඇති කිරීමට සමත් අන්දමට වර්ධනය වූ පසුව එන්නත් ලබාදීම මගින් රෝග සඳහා ආරක්ෂාව ලබාදිය හැකිය. අමතර එන්නත් වර්ග ලබාදීම මගින් පුර්ණ ප්රතිශක්තීකරණය ලබාදීමට පුළුවන. මෙමගින් සංකීර්ණ එන්නත් වැඩසටහනක් නිර්මාණය වුණි. ඇමරිකා එක්සත් ජනපදයෙහි ප්රතිශක්තීකරණ ක්රියාවලිය හා සම්බන්ධ උපදේශාත්මක ...
Hantavirus vaccine
This virus-related article is a stub. You can help Wikipedia by expanding it. *v ... The first hantavirus vaccine was developed in 1990 initially for use against Hantaan River virus which causes one of the most ... They include a recombinant vaccine and vaccines derived from HTNV and PUUV viruses. However, their prospects are unclear.[1] ... Other hantaviruses for which the vaccine is used include Seoul (SEOV) virus. However the vaccine is thought not to be effective ...
Ivermectin
... is also being studied as a potential antiviral agent against the viruses chikungunya and yellow fever.[66] ... abamectin and ivermectin as antivirals against chikungunya and other alphaviruses". Antiviral Research. 126: 117-24. doi: ...
Smallpox
Variola virus Smallpox was caused by infection with Variola virus, which belongs to the genus Orthopoxvirus, the family ... While the Dryvax virus was cultured in the skin of calves and freeze-dried, ACAM2000s virus is cultured in kidney epithelial ... During the 19th century, the cowpox virus used for smallpox vaccination was replaced by vaccinia virus. Vaccinia is in the same ... In 2017, Canadian scientists recreated an extinct horse pox virus to demonstrate that the smallpox virus can be recreated in a ...
എച്ച് ഐ ബി വാക്സിൻ - വിക്കിപീഡിയ
ഹീമൊഫെലസ് ഇൻഫ്ലുവെൻസെ ടൈപ്പ് ബി വാക്സിൻ (Haemophelus influenzae type B) (HIB) അണുബാധ തടയുന്നതിനുള്ള പ്രതിരോധ മരുന്നാണു Haemophelus influenzae type B വാക്സിൻ. ഈ വാക്സിനെ ഒരു ദൈനംദിന വാക്സിനേഷൻ പ്രക്രിയയിൽ ഉൾപെടുത്തിയിട്ടുള്ള രാജ്യങ്ങളിൽ HIB അണുബാധ 90% ൽ അധികം കുറഞ്ഞിട്ടുണ്ട് അതുകൊണ്ടുതന്നെ മെനിഞ്ചൈറ്റിസ്, ന്യൂമോണിയ, എപ്പിഗ്ലൊട്ടിസ് എന്നീ രോഗങ്ങളും കുറഞ്ഞിട്ടുണ്ട്.[1] ...
Molluscum contagiosum
MC is caused by a poxvirus called the molluscum contagiosum virus (MCV).[1] The virus is spread either by direct contact ... Molluscum contagiosum virus spread by direct contact or contaminated objects[4]. Risk factors. Weak immune system, atopic ... Rubella virus *Rubella. *Congenital rubella syndrome ("German measles" ). *Alphavirus infection. *Chikungunya fever ... Chen, X; Anstey, AV; Bugert, JJ (October 2013). "Molluscum contagiosum virus infection". Lancet Infectious Diseases. 13 (10): ...
Lassa virus
Lassa viruses[12][13] are enveloped, single-stranded, bisegmented, ambisense RNA viruses. Their genome[14] is contained in two ... Lassa virus is an emerging virus and a select agent, requiring Biosafety Level 4-equivalent containment. It is endemic in West ... The life cycle of Lassa virus is similar to the Old World arenaviruses. Lassa virus enters the cell by the receptor-mediated ... "Viruses. 4: 2031-2048. doi:10.3390/v4102031. PMC 3497040. PMID 23202452.. *^ a b Donaldson, Ross I. (2009). The Lassa Ward:One ...
Chickenpox
This is to keep the virus in circulation thereby exposing the population to the virus at an early age, when it is less harmful ... After a chickenpox infection, the virus remains dormant in the body's nerve tissues. The immune system keeps the virus at bay, ... "Understanding Viruses (2nd ed.). Jones & Bartlett. p. 459. ISBN 978-0-7637-8553-6. . Archived from the original on 1 October ... Rubella virus *Rubella. *Congenital rubella syndrome ("German measles" ). *Alphavirus infection. *Chikungunya fever ...
List of vaccine topics
Chikungunya vaccine[5]. *Dengue vaccine for humans[6]. *Eastern Equine encephalitis virus vaccine for humans[7] ... Virus. Diseases or conditions. Vaccine(s). Brands Hepatitis A virus. Hepatitis A. Hepatitis A vaccine. Havrix, Avaxim, VAQTA, ... Polio virus. Poliomyelitis. Polio vaccine. Kinrix, Quadracel, Pediarix, Pentacel, Pediacel, Ipol Rabies virus. Rabies. Rabies ... Variola virus. Smallpox. Smallpox vaccine. Dryvax, ACAM2000, Imvanex Yellow fever virus. Yellow fever. Yellow fever vaccine. YF ...
Category:Diseases spread by insects - Simple English Wikipedia, the free encyclopedia
Text is available under the Creative Commons Attribution/Share-Alike License and the GFDL; additional terms may apply. See Terms of Use for details ...
Wolbachia, a enciclopedia libre
Nora virus, nodavirus Flock house, virus da parálise do grilo, virus Chikungunya, e virus do Nilo occidental.[18][19][20] No ... As moscas infectadas pola bacteria son máis resistentes a virus de ARN como o virus de Drosophila C, ... 2009). "A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium". Cell 139 (7): 1268-78 ... Hedges, Lauren; Brownlie, Jeremy; O'Neill, Scott; Johnson, Karyn (2008). "Wolbachia and Virus Protection in Insects". Science ...
World Health Day
... chikungunya, Japanese encephalitis and yellow fever.[14] More than half of the world's population is at risk of these diseases ... viruses, parasites or chemical substances - is responsible for more than 200 diseases, and is linked to the deaths of some 2 ...
Kaposi's sarcoma-associated herpesvirus
Infection with this virus is thought to be lifelong, but a healthy immune system will keep the virus in check. Many people ... When the virus enters into lytic replication, thousands of virus particles can be made from a single cell, which usually ... When the virus reactivates into lytic replication, it is believed that the virus genome is replicated as a continuous linear ... The mechanisms by which the virus is contracted are not well understood. Healthy individuals can be infected with the virus and ...
Natural killer cell
Chikungunya virus, HIV, or viral hepatitis. However, whether these virus infections trigger the expansion of adaptive NKG2C+ NK ... For NK cells to defend the body against viruses and other pathogens, they require mechanisms that enable the determination of ... NK cells provide rapid responses to virus-infected cells, acting at around 3 days after infection, and respond to tumor ... The distinction between apoptosis and cell lysis is important in immunology: lysing a virus-infected cell could potentially ...
വില്ലൻ ചുമ വാക്സിൻ - വിക്കിപീഡിയ
വില്ലൻചുമയെ പ്രതിരോധിക്കുന്ന വാക്സിൻ ആണ് പെർട്ടുസ്സിസ് വാക്സിൻ(Pertussis vaccine).[1] ഇവ പ്രധാനമായും രണ്ടുതരത്തിലാണുള്ളത്: മുഴു-കോശ വാക്സിനും അസെല്ലുലാർ വാക്സിനും. മുഴുകോശ വാക്സിൻ ഏകദേശം 78% ഫലപ്രദമാണ് അതേസമയം അസെല്ലുലാർ വാക്സിൻ 71 മുതൽ 85% വരെ ഫലപ്രദമാണ്. വർഷം തോറും ഈ വാക്സിന്റെ വീര്യം 2 മുതൽ 10 % വരെ കുറഞ്ഞു വരുന്നതായും അസെല്ലുലാർ വാക്സിന്റെ കാര്യത്തിൽ ദ്രുത ഗതിയിൽ കുറഞ്ഞു വരുന്നതായും ...
Chikungunya virus | CDC
Information on Chikungunya virus. Provided by the U.S. Centers for Disease Control and Prevention. ... chikungunya virus was found for the first time in the Americas on islands in the Caribbean. There is a risk that the virus will ... Chikungunya virus is spread to people by the bite of an infected mosquito. The most common symptoms of infection are fever and ... When traveling to countries with chikungunya virus, use insect repellent, wear long sleeves and pants, and stay in places with ...
ArboCat Virus: Chikungunya (CHIKV)
Virus Sections. Virus Name/Prototype. Original Source. Method of Isolation. Virus Properties. Antigenic Relationship. Biologic ... Arthropod species & virus source(a) Method of Infection log10/ml (b) Incubation period (c) Transmision by bite (d) Assay of ... Click on the PDF icon to the left to view a copy of this virus entry in PDF format. You can get a copy of the PDF viewer by ...
ArboCat Virus: Chikungunya (CHIKV)
Chikungunya virus: MedlinePlus Medical Encyclopedia
The name chikungunya (pronounced chik-en-gun-ye) is an African word meaning bent ... Chikungunya is a virus passed to humans by the bite of infected mosquitoes. Symptoms include fever and severe joint pain. ... How Chikungunya Can Spread. Mosquitoes spread the virus to humans. Mosquitoes pick up the virus when they feed on infected ... Chikungunya virus. www.cdc.gov/chikungunya. Updated December 17, 2018. Accessed May 29, 2019. ...
Chikungunya Virus Infection Symptoms & Treatment
Read information written by doctors about Chikungunya virus infection transmission (how you get it), common symptoms are fever ... What are Chikungunya virus infection symptoms and signs?. *How do health care professionals diagnose Chikungunya virus ... What are Chikungunya virus infection symptoms and signs?. *How do health care professionals diagnose Chikungunya virus ... home/infectious disease health center/infectious disease a-z list/chikungunya virus infection center /chikungunya virus ...
Chikungunya virus, southeastern France. - PubMed - NCBI
Phylogenetic relationships among chikungunya virus isolates from cases of chikungunya fever in France, based on complete E2-6K- ... Chikungunya virus, southeastern France.. Grandadam M1, Caro V, Plumet S, Thiberge JM, Souarès Y, Failloux AB, Tolou HJ, Budelot ... In September 2010, autochthonous transmission of chikungunya virus was recorded in southeastern France, where the Aedes ... viral genomes of imported and autochthonous isolates indicated new features for the potential emergence and spread of the virus ...
Chikungunya virus infection: an overview. - PubMed - NCBI
Chikungunya virus infection: an overview.. Caglioti C1, Lalle E, Castilletti C, Carletti F, Capobianchi MR, Bordi L. ... Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus belonging to the Togaviridae family, first isolated in Tanzania ... Diagnosis is based on the detection of virus by molecular methods or by virus culture on the first days of infection, and by ... Differential diagnosis should take into account the cross-reactivity with other viruses from the same antigenic complex (i.e. ...
Chikungunya Virus Arrives In Americas - Business Insider
... the chikungunya virus had infected at least 200 people. But in the last week alone, it infected more than twice that number. ... Other famous examples include the West Nile virus and dengue fever. Both dengue and the chikungunya virus are spread by the ... From early December to mid-January, the chikungunya virus had infected at least 200 people, epidemiologists say. But in the ... The virus is not usually fatal, though, with 1 death in every 1,000 cases, and then usually only in the elderly or immune- ...
Chikungunya Virus Infection Symptoms & Treatment
Read information written by doctors about Chikungunya virus infection transmission (how you get it), common symptoms are fever ... What are Chikungunya virus infection symptoms and signs?. *How do health care professionals diagnose Chikungunya virus ... Chikungunya Virus (Chikungunya Infection). *Medical Author: Charles Patrick Davis, MD, PhD *Medical Editor: Melissa Conrad ... The infection caused by Chikungunya virus is was first described in East Africa in 1952. The virus is transmitted by mosquitoes ...
2020 Case Counts in the US | Chikungunya virus | CDC
Information on Chikungunya virus. Provided by the U.S. Centers for Disease Control and Prevention. ... Laboratory-confirmed chikungunya virus disease cases reported to ArboNET by state or territory - United States. Travel- ... Chikungunya virus disease cases* reported to ArboNET by states and territories - United States, 2020 (as of May 25, 2021). ... Chikungunya virus disease became a nationally notifiable condition in 2015. Cases are reported to CDC by state and local health ...
Threatwatch: Chikungunya virus spreads in the Americas | New Scientist
... raising the prospect of the virus spreading across the Americas ... Caribbean has reported locally acquired cases of chikungunya, ... Threatwatch: Chikungunya virus spreads in the Americas. Threatwatch is your early warning system for global dangers, from ... A dozen people on the tiny Caribbean island of St Martin have been infected with the chikungunya virus. It is the first time ... But blood samples sent for testing in France confirmed the presence of chikungunya. The virus would have been brought to the ...
BioCollections Worldwide Chikungunya Virus Assay | GenomeWeb
... assay follows the US Centers for Disease Control and Preventions real-time RT-PCR protocol for detection of Chikungunya virus ... BioCollections Worldwide said today that it is now offering a laboratory-developed test for the detection of Chikungunya virus ... BioCollections Worldwide said today that it is now offering a laboratory-developed test for the detection of Chikungunya virus ... assay follows the US Centers for Disease Control and Preventions real-time RT-PCR protocol for detection of Chikungunya virus ...
Chikungunya Virus Has Spread To US
Chikungunya virus has made its appearance well known in the United States this year. In fact, cases have gone from a normal 28 ... The virus was first recorded in 1952 in Africa then Asia, but in 2013 it began to spread to the Caribbean and Haiti. Travelers ... The virus is transmitted by mosquito, but not human to human. Fortunately, it isnt fatal, but it is extremely painful. ... Chikungunya causes a rash, fever, and excruciating joint pain that last from five to seven days. However, Dr. William Schaffner ...
Two Contract Mosquito-Borne Chikungunya Virus in Florida - WSJ
Public health officials in Florida on Thursday confirmed that two people in the state contracted the mosquito-borne chikungunya ... Two Contract Mosquito-Borne Chikungunya Virus in Florida. Puerto Rico Declares Chikungunya Epidemic With Over 100 Confirmed ... The virus, which is transmitted from mosquitoes to humans and vice versa, has been spreading rapidly through the Caribbean ... health officials in Florida said Thursday that two people in the state contracted the mosquito-borne chikungunya virus locally ...
Dropbox - virus chikungunya en las americas sep 2014.pdf
Chikungunya Virus Confirmed in 15 States: CDC
A mosquito-borne virus that has sickened tens of thousands of people throughout the Carribbean is now threatening the U.S., ... The chikungunya virus - or chik-v - causes high fever and severe pain, and there is no vaccine to prevent it, CBS News ... this virus, back to the United States, Dr. Schaffner said. We have the kind of mosquito that will transmit this virus here in ... A mosquito-borne virus that has sickened tens of thousands of people throughout the Carribbean is now threatening the U.S., ...
Chikungunya: a re-emerging virus
... a virus transmitted by Aedes spp mosquitoes--has re-emerged in Africa, southern and southeastern Asia, and the Indian Ocean ... Chikungunya: a re-emerging virus Lancet. 2012 Feb 18;379(9816):662-71. doi: 10.1016/S0140-6736(11)60281-X. Epub 2011 Nov 17. ... In the past decade, chikungunya--a virus transmitted by Aedes spp mosquitoes--has re-emerged in Africa, southern and ... The virus is endemic to tropical regions, but the spread of Aedes albopictus into Europe and the Americas coupled with high ...
Chikungunya virus | MSDSonline
PATHOGENICITY/TOXICITY: Translated from the African dialect of Swahili or Makonde, chikungunya means, "that which bends up" (1 ... SUSCEPTIBILITY TO DISINFECTANTS: No information specific to CHIKV; however, most lipid enveloped viruses are sensitive to 70% ( ... SYNONYM OR CROSS REFERENCE: CHIKV (1-6), CHIK (2, 7-9), and chikungunya fever (2, 10). ... the virus was isolated repeatedly from numerous countries in Central and Southern Africa, including Sudan, Uganda, Democratic ...
Structural basis of Chikungunya virus inhibition by monoclonal antibodies | PNAS
Mayaro virus (MAYV), Ross River virus (RRV), Sagiyama virus, Semliki Forest virus (SFV) and Una virus (SI Appendix, Fig. S9B). ... Environmental Research Institute for the generous gifts of the Chikungunya virus Ross strain and Chikungunya virus East African ... Dynamics of chikungunya virus cell entry unraveled by single-virus tracking in living cells. J. Virol. 90, 4745-4756 (2016).. ... Chikungunya virus (CHIKV), a single-stranded positive-sense RNA envelope virus, is an emerging alphavirus transmitted to humans ...
How Will Chikungunya Virus Spread? DARPA Announces Challenge | Live Science
Defense Advanced Research Projects Agency is asking innovators to build models that predict the spread of chikungunya virus ... DARPAs challenge, called CHIKV (which stands for chikungunya virus), aims to find ways to forecast the spread of the virus, ... This image shows magnified particles of the Chikungunya virus, which is spread by mosquitos. The virus was found in the ... How Will Chikungunya Virus Spread? DARPA Announces Challenge. By Bahar Gholipour 15 August 2014. ...
Guillain-Barre syndrome complicating chikungunya virus infection | SpringerLink
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which presents with symptoms of fever, rash, arthralgia, and ... Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which presents with symptoms of fever, rash, arthralgia, and ... Guillain-Barre syndrome Chikungunya virus Plasmapharesis Mosquito-borne diseases This is a preview of subscription content, log ... Chandak NH, Kashyap RS, Kabra D et al (2009) Neurological complications of chikungunya virus infection. Neurol India 57:177-180 ...
'Super-adapted' chikungunya virus a possibility - The Hindu
The chikungunya virus circulating in parts of India as well as Sri Lanka and South-East Asia could gain the ability to spread ... Super-adapted chikungunya virus a possibility N. Gopal Raj June 25, 2014 21:59 IST Updated: June 25, 2014 21:59 IST ... The chikungunya virus circulating in parts of India as well as Sri Lanka and South-East Asia could gain the ability to spread ... Although the E2-K252Q mutation has continued to turn up in chikungunya viruses isolated in Kerala, the E2-L210Q had not been ...
Chikungunya Virus | J. Craig Venter Institute
Comprehensive Genome Scale Phylogenetic Study Provides New Insights on the Global Expansion of Chikungunya Virus. ... Differing epidemiological dynamics of Chikungunya virus in the Americas during the 2014-2015 epidemic. ... Chikungunya (CHIKV) has been the cause of multiple outbreaks and infects greater than one million people every year. CHIKV was ... which increases the need to better understand the sequence diversity of these viruses and how any viral mutations affect the ...
Chikungunya Virus
... Chikungunya (pronunciation: chik-en-gun-ye) virus is transmitted to people by mosquitoes. The most common ... There is no vaccine to prevent or medicine to treat Chikungunya virus. If you believe you have Chikungunya, prevent mosquito ... Chikungunya virus was found for the first time in the Americas on islands in the Caribbean. There is a risk that the virus will ... During the first week of infection, Chikungunya virus can be found in the blood and passed from an infected person to a ...
Mexico detects first case of mosquito-borne chikungunya virus | Fox News
Mexico has detected its first domestic case of the painful mosquito-borne viral disease chikungunya in the southwest of the ... Chikungunya, a virus more commonly found in Africa and Asia and transmitted by the aedes aegypti mosquito that causes dengue ... Mexico detects first case of mosquito-borne chikungunya virus. Published November 17, 2014. Reuters ... Chikungunya has already appeared in much of the Caribbean, Central America and the United States. A handful of people have had ...
Faster, cheaper test developed for chikungunya virus - SciDev.Net
... a mosquito-bourne virus common in Africa and Asia. ... Faster, cheaper test developed for chikungunya virus. By: ... Chikungunya virus is spread by mosquitoes. It causes high fevers and severe pain in ankle and wrist joints. The disease affects ... Chikungunya virus is spread by mosquitoes. It causes high fevers and severe pain in ankle and wrist joints. The disease affects ... Faster, cheaper test developed for chikungunya virus. By Sanjit Bagchi. Researchers from Japan and India have developed a rapid ...
Chikungunya Virus Treatment & Management: Approach Considerations, Prevention, Future Perspectives
Chikungunya fever is a self-remitting febrile viral illness that has been associated with frequent outbreaks in tropical ... encoded search term (Chikungunya Virus) and Chikungunya Virus What to Read Next on Medscape ... Research into development of a live-virus and attenuated-virus vaccine against Chikungunya virus is ongoing. However, no ... Zika and chikungunya: mosquito-borne viruses in a changing world. Ann N Y Acad Sci. 2017 Jul. 1399 (1):61-77. [Medline]. ...
Chikungunya virus-like particle vaccine
Chikungunya virus (CHIKV) is an arthropod-borne alphavirus (family Togaviridae) and is the causative agent of chikungunya fever ... Chikungunya virus (CHIKV) is an arthropod-borne alphavirus (family Togaviridae) and is the causative agent of chikungunya fever ... chikungunya virus - virus-like particles - viral diseases - aedes albopictus - disease vectors - vaccines - vaccine development ... live-attenuated virus, chimeric virus vaccines, DNA vaccines, adenoviral vectored vaccines, subunit protein vaccines and virus- ...
CHIKVInfectionMosquitoesFeverOutbreaksAlphavirusEndemicInfectionsOutbreak of chikungunyaEpidemicAntibodyChik-en-gun-yeFloridaPathogenesisTravelersTransmissionTransmitAmericasRashImmunityRarely fatalAcuteViral diseaseReplicationCaribbeanHumansDiseaseZika and Chikungunya VirusesCase of Chikungunya virusTest for chikungunya virusStrain of chikungunya virusStrains of chikungunya virusFatalIllnessSpreadIndiaDiseasesDengue virusOfficialsPrevalentVaccinesPresence of chikungunyaAedes aegypti and aedes albopictusSevere joint painAlbopictus
CHIKV53
- Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus belonging to the Togaviridae family, first isolated in Tanzania in 1952. (nih.gov)
- PATHOGENICITY/TOXICITY: Translated from the African dialect of Swahili or Makonde, chikungunya means, "that which bends up" (1, 2, 12), "what bends" (10), or "to walk bent over" (13), and refers to the effect of the incapacitating arthralgia experienced by patients with CHIKV fever (1). (msdsonline.com)
- Chikungunya virus (CHIKV) is a significant human pathogen that causes debilitating and long-lasting arthritis. (pnas.org)
- Chikungunya virus (CHIKV) is an emerging viral pathogen that causes both acute and chronic debilitating arthritis. (pnas.org)
- DARPA's challenge , called CHIKV (which stands for chikungunya virus), aims to find ways to forecast the spread of the virus, and predict future outbreaks in the Caribbean, along with North, Central and South America. (livescience.com)
- Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which presents with symptoms of fever, rash, arthralgia, and occasional neurologic disease. (springer.com)
- 2010) A child with serious chikungunya virus (CHIKV) infection requiring intensive care, after an outbreak. (springer.com)
- I think it is important to do comprehensive surveillance to monitor both CHIKV [chikungunya virus] evolution and rates of herd immunity and disease incidence. (thehindu.com)
- Chikungunya (CHIKV) has been the cause of multiple outbreaks and infects greater than one million people every year. (jcvi.org)
- 1,776 inhabitants to determine chikungunya virus (CHIKV) thralgia is often severely debilitating and may last for seroprevalence, identify factors associated with expo- sure, and estimate the symptomatic infection rate. (cdc.gov)
- After the introduction of CHIKV into the Carib- ciodemographic and clinical data by interview and tested bean region in 2013, the virus spread rapidly, caus- serum samples for CHIKV IgG. (cdc.gov)
- Chikungunya virus (CHIKV) is an arthropod-borne alphavirus (family Togaviridae ) and is the causative agent of chikungunya fever. (wur.nl)
- Dengue virus (DENV) and Chikungunya virus (CHIKV) are arboviruses that share the same Aedes mosquito vectors and thus overlap in their endemic areas. (hindawi.com)
- Dengue virus (DENV) and Chikungunya virus (CHIKV) are single-stranded, positive-sense RNA viruses. (hindawi.com)
- While DENV and CHIKV present similarly as an acute febrile illness, these two viruses have vastly different management strategies and outcomes. (hindawi.com)
- The mosquito-transmitted Chikungunya virus (CHIKV) is associated with increased morbidity and debilitating chronic musculoskeletal disease in infected humans. (springer.com)
- Chikungunya virus (CHIKV, family Togaviridae, genus Alphavirus) was first isolated during an epidemic in Tanzania in 1952 and 1953 (1). (thefreelibrary.com)
- CHIKV and dengue virus (DENV) are both transmitted by Aedes mosquitoes, such as A. aegypti and A. albopictus. (thefreelibrary.com)
- A new method of vaccine creation for Chikungunya virus (CHIKV) using a technique called large scale random codon re-encoding was developed by researchers. (medindia.net)
- Arthritogenic alphaviruses, including Chikungunya virus (CHIKV), are responsible for acute fever and arthralgia, but can also lead to chronic symptoms. (plos.org)
- Chikungunya virus (CHIKV) is an arthropod-borne virus that belongs to the Alphavirus genus. (plos.org)
- Chikungunya virus (CHIKV) is an arbovirus transmitted to humans by mosquito bite. (archives-ouvertes.fr)
- Chikungunya virus (CHIKV), an Old World alphavirus, is transmitted to humans by infected mosquitoes and causes acute rash and arthritis, occasionally complicated by neurologic disease and chronic arthritis. (pnas.org)
- Chikungunya virus (CHIKV) is an arbovirus capable of causing a severe and often debilitating rheumatic syndrome in humans. (jci.org)
- This virus, which we term SKE, displayed diminished replication in skeletal muscle cells in a mouse model of CHIKV disease. (jci.org)
- To the Editor: Chikungunya virus (CHIKV) first emerged in Indian Ocean islands off the eastern coast of Africa in 2005 and was responsible for large-scale epidemics on the islands of Reunion, Comoros, Mayotte, Mauritius, Madagascar, and Seychelles (1-4). (thefreelibrary.com)
- To report demographic and self-reported clinical characteristics associated with persistent and severe arthralgia 8-12 months post-chikungunya virus (CHIKV) infection. (uwi.edu)
- Chikungunya virus (CHIKV) is an emerging arbovirus associated with several recent large-scale epidemics. (nih.gov)
- Chikungunya fever is an acute febrile illness caused by the chikungunya virus (CHIKV), which is transmitted to humans by Aedes mosquitoes. (eurosurveillance.org)
- This enables estimation of the current total population-at-risk of CHIKV transmission and identification of areas where the virus may spread to in the future. (eurosurveillance.org)
- The Ross River Virus (RRV) and Chikungunya Virus (CHIKV) are mosquito-borne alphavirus infections. (medindia.net)
- Several arboviruses, including dengue virus (DENV), Zika virus (ZIKV) and chikungunya virus (CHIKV), transmitted by Aedes mosquitoes, circulate in northeast Brazil. (unboundmedicine.com)
- Chikungunya virus (CHIKV) is a re-emerging alphavirus that causes debilitating acute and chronic arthritis. (jimmunol.org)
- Chikungunya virus (CHIKV) is a re-emerging mosquito-borne enveloped alphavirus in the Togaviridae family. (jimmunol.org)
- Historically, CHIKV was transmitted principally by Aedes aegypti mosquitoes, but in 2006 the virus acquired a single mutation (A226V) in the E1 protein that facilitated enhanced replication and transmission in Aedes albopictus mosquitoes, which expanded its geographical range ( 5 ). (jimmunol.org)
- After inoculation of CHIKV into the skin, the virus likely replicates in fibroblasts, mesenchymal cells, and osteoblasts ( 20 , 21 ). (jimmunol.org)
- The Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus that can cause widespread outbreaks of a debilitating arthritis-like human disease. (sciencephoto.com)
- Since the role of cellular kinases in alphavirus replication is unknown, we profiled kinetic changes in host kinase abundance and phosphorylation following chikungunya virus (CHIKV) infection of fibroblasts. (asm.org)
- Chikungunya virus (CHIKV) causes a febrile disease associated with chronic arthralgia, which may progress to neurological impairment. (asm.org)
- Chikungunya fever (CF) is an ongoing public health problem in tropical and subtropical regions of the world, where control of the CHIKV vector, Aedes mosquitos, has failed. (asm.org)
- The rheumatic symptoms associated with chikungunya virus (CHIKV) infection include polyarthralgia, polyarthritis, morning stiffness, joint edema, and erythema. (mdpi.com)
- Chikungunya virus (CHIKV) is a small (60-70 nm, 12 Kb), single-stranded positive-sense RNA virus in the Alphavirus genus of the Togaviridae family [ 1 , 2 ]. (mdpi.com)
- Chikungunya virus (CHIKV) is a positive-sense RNA virus transmitted by Aedes mosquitoes. (mdpi.com)
- CHIKV establishes a persistent infection in NHPs, particularly in cynomolgus macaques, because infectious virus could be recovered from spleen, liver, and muscle as late as 44 days post infection. (mdpi.com)
- Chikungunya virus (CHIKV) is a mosquito-transmitted RNA virus that causes acute febrile illness and severe debilitating joint pain. (mdpi.com)
- CHIKV belongs to the Semliki Forest virus clade of Old World Alphaviruses [ 1 , 2 ]. (mdpi.com)
- In 2006, an outbreak of Chikungunya virus (CHIKV) of the Asian genotype affected over 200 people in Bagan Panchor village in Malaysia. (ajtmh.org)
- albopictus highlighting the co-ancestry of the different derived populations and the dissemination and transmission efficiencies for Chikungunya virus (CHIKV). (pasteur.fr)
- Chikungunya virus (CHIKV) has been detected sporadically since the 1950s and includes three distinct co-circulating genotypes. (jcvi.org)
- Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for several significant outbreaks of debilitating acute and chronic arthritis and arthralgia over the past decade. (asm.org)
- Zika virus (ZIKV) and chikungunya virus (CHIKV) are highly pathogenic arthropod-borne viruses that present a serious health threat to humans. (wur.nl)
- aegypti was competent for both viruses with transmission rates up to 73% (ZIKV) and 21% (CHIKV). (wur.nl)
- FORT COLLINS, Colo.--(BUSINESS WIRE)--Inviragen, Inc. today announced that the National Institute of Allergy and Infectious Diseases (NIAID), a division of the National Institutes of Health, has awarded a four-year grant of over $3 million for the characterization and development of a novel recombinant chikungunya virus (CHIKV) vaccine. (fiercebiotech.com)
Infection88
- There is no vaccine to prevent or medicine to treat chikungunya virus infection. (cdc.gov)
- The infection caused by Chikungunya virus is was first described in East Africa in 1952. (medicinenet.com)
- Is Chikungunya virus infection contagious? (medicinenet.com)
- Chikungunya virus infection is not considered to be contagious because there is no direct human to human transfer of Chikungunya viruses, so infected individuals cannot directly transfer the virus to another human because the virus has to pass through a mosquito first. (medicinenet.com)
- What are Chikungunya virus infection symptoms and signs? (medicinenet.com)
- The Chikungunya disease may be diagnosed by blood antibody tests that distinguish between this infection and dengue fever , a similar viral disease, and other diseases. (medicinenet.com)
- Chikungunya virus infection: an overview. (nih.gov)
- Diagnosis is based on the detection of virus by molecular methods or by virus culture on the first days of infection, and by detection of an immune response in later stages. (nih.gov)
- What is the treatment for Chikungunya virus infection? (rxlist.com)
- Once a person recovers from Chikungunya infection, researchers suggest the person develops life-long immunity to the virus type. (rxlist.com)
- Is it possible to prevent a Chikungunya virus infection? (rxlist.com)
- The assay follows the US Centers for Disease Control and Prevention's real-time RT-PCR protocol for detection of Chikungunya virus, and detects cases in the acute stage of infection in about five hours, BCW said. (genomeweb.com)
- Both groups of researchers found a potential means to stop T cells from inappropriately trafficking to the joints and causing arthritis, a hallmark of acute Chikungunya virus infection - using a mouse model of the disease. (eurekalert.org)
- Chandak NH, Kashyap RS, Kabra D et al (2009) Neurological complications of chikungunya virus infection. (springer.com)
- Handler MZ, Handler NS, Stephany MP et al (2016) Chikungunya fever: an emerging viral infection threatening North America and Europe. (springer.com)
- Lebrun G, Chadda K, Reboux A-H et al (2009) Guillain-Barré syndrome after chikungunya infection. (springer.com)
- Wielanek AC, Monredon JD, Amrani ME et al (2007) Guillain-Barré syndrome complicating a chikungunya virus infection. (springer.com)
- During 2011-2013, a nationwide outbreak of chikungunya fever surveillance under the Philippine Integrated Disease virus infection occurred in the Philippines. (cdc.gov)
- The most common symptoms of Chikungunya virus infection are fever and joint pain. (cor.net)
- During the first week of infection, Chikungunya virus can be found in the blood and passed from an infected person to a mosquito through mosquito bites. (cor.net)
- Poor glycemic control in patients with diabetes who have Chikungunya infection has been reported. (medscape.com)
- In 2017, Chang et al reported that, although about 25% of individuals with Chikungunya infection eventually develop persistent arthritis, follow-up testing revealed no detectable Chikungunya virus on synovial fluid analysis among 38 study participants. (medscape.com)
- These two viruses also cause similar clinical presentations, especially in the initial stages of infection, with neither virus possessing any specific distinguishing clinical features. (hindawi.com)
- Concurrent infection with both viruses, transmitted from either two different mosquitos or one dually infected mosquito, is possible [ 5 , 6 ]. (hindawi.com)
- Barry Alto, an associate professor of entomology at the UF Institute of Food and Agricultural Sciences, led a team of UF/IFAS researchers that measured mosquito infection and transmission of the emergent strains of chikungunya -- Asian and Indian Ocean - in Aedes aegypti and Aedes albopictus mosquitoes. (newswise.com)
- Chikungunya infection is notifiable in New Zealand as an arboviral disease. (health.govt.nz)
- Chikungunya virus infection should be considered in patients with acute onset of fever and polyarthralgia, especially travellers who have recently returned from areas with known virus transmission. (health.govt.nz)
- As Chikungunya infection may cause a rash that could be confused other diseases such as dengue and measles, these other diseases do need to be ruled out. (health.govt.nz)
- They were also interested in studying the mechanisms behind Zika virus infection and transmission in mosquitoes. (eurekalert.org)
- Four, seven, 10 and 17 days after the mosquitoes fed on Zika-virus-infected blood the researchers tested them for Zika virus infection, assessed whether the virus had disseminated -- or spread to other tissues in the mosquito, and examined whether the virus made its way to the mosquito saliva, where it must be present to be transmitted. (eurekalert.org)
- If people develop arthritis as a result of infection with the virus, they are given anti-inflammatory drugs, he said. (livescience.com)
- Since there is no vaccine to prevent chikungunya and no medicine to treat it, people who are traveling to these areas should be aware of this infection and take steps to avoid mosquito bites , such as wearing repellent and long-sleeves and pants if possible," Gérardin said. (livescience.com)
- Among the adults who were infected with the virus and developed encephalitis as a result of the infection, the disabilities included dementia and epilepsy, according to the study, published today (Nov. 25) in the journal Neurology. (livescience.com)
- Chikungunya virus infection is common in Thailand, and routine use of diagnostic assays is needed. (thefreelibrary.com)
- Chicken pox is an acute and highly contagious viral infection caused by the varicella zoster virus. (medindia.net)
- We report eight recent cases of Chikungunya virus infection in travellers to Australia. (mja.com.au)
- C hikungunya virus is a mosquito-borne alphavirus infection first described in Tanzania in 1952. (mja.com.au)
- We report eight cases of Chikungunya virus infection in travellers to Australia between February 2006 and September 2007. (mja.com.au)
- The eight cases of Chikungunya virus infection were identified after reviewing the database of the Victorian Infectious Diseases Reference Laboratory between February 2006 and September 2007. (mja.com.au)
- The review was undertaken to raise awareness among medical practitioners of Chikungunya virus infection. (mja.com.au)
- The first patient diagnosed with Chikungunya virus infection was a 59-year-old Mauritian man who presented to hospital 5 days after travelling from Mauritius for the 2006 Commonwealth Games. (mja.com.au)
- These eight patients illustrate the typical clinical presentation of Chikungunya virus infection. (mja.com.au)
- Chikungunya virus infection is believed to confer lifelong immunity. (mja.com.au)
- The viraemic phase of alphaviruses is 2-8 days, so the success of RT-PCR to detect the virus depends on early presentation and the clinical suspicion of a possible alphavirus infection. (mja.com.au)
- Is the Subject Area "Chikungunya infection" applicable to this article? (plos.org)
- In 2006, a Chikungunya outbreak occurred in La Réunion Island, during which we constituted a prospective cohort of viremic patients (n = 180) and defined the clinical and biological features of acute infection. (plos.org)
- It also illustrates how the analysis of clinical and biological data from human cohorts and the development of animal and cellular models of infection has helped to identify the tissue and cell tropisms of the virus and to decipher host responses in benign, severe or persistent disease. (archives-ouvertes.fr)
- Given chikungunya's inevitable crossover to America, here's what you need to know about the virus - and how you can protect yourself from infection. (foxnews.com)
- Chikungunya is a viral infection transmitted to humans by infected mosquitos - mainly by the Aedes aegypti and Aedes albopictus species. (foxnews.com)
- Infection of the chikungunya virus occurs when a person gets bitten by a mosquito that has previously fed on another infected individual. (foxnews.com)
- The virus, first identified in Tanzania in 1953, causes severe rashes and joint pains, but is rarely fatal, and the infection was considered benign. (virology.ws)
- Since its discovery over 50 years ago, infection by chikungunya virus was known to be spread by mosquitoes, primarily Aedes aegypti , which feeds almost exclusively on humans. (virology.ws)
- Since the first documented autochthonous transmission of chikungunya virus in the Caribbean island of Saint Martin in 2013, the infection has been reported within the Caribbean region as well as North, Central and South America. (eurosurveillance.org)
- As of Dec. 10, the WHO states that "two confirmed, four probable, and twenty suspected cases of chikungunya infection have been reported. (medicaldaily.com)
- In late 2013, chikungunya virus was found for the first time in the Americas on islands in the Caribbean… There is no vaccine to prevent or medicine to treat chikungunya virus infection. (cogwriter.com)
- A new method for permanently marking cells infected with chikungunya virus could reveal how the virus continues to cause joint pain for months to years after the initial infection, according to a study published August 29 in the open-access journal PLOS Pathogens by Deborah Lenschow of Washington University School of Medicine in St. Louis, and colleagues. (brightsurf.com)
- Approximately 30 to 60 percent of people infected with the virus continue to experience joint pain for months to years after the initial infection. (brightsurf.com)
- Using this system, they show in mice that marked cells surviving chikungunya virus infection are a mixture of muscle and skin cells that are present for at least 112 days after initial virus inoculation. (brightsurf.com)
- Treatment of mice with an antibody that blocks chikungunya virus infection reduces the number of marked cells in the muscle and skin. (brightsurf.com)
- Taken together, the findings provide further evidence for musculoskeletal cells as targets of chikungunya virus infection in the acute and chronic stages of disease. (brightsurf.com)
- 2019) Dermal and muscle fibroblasts and skeletal myofibers survive chikungunya virus infection and harbor persistent RNA. (brightsurf.com)
- A particular cause for concern for the people affected is an increase in the number of cases of brain malformations in newborns (microcephaly), for which a link with Zika virus infection has meanwhile been confirmed. (infectioncontroltoday.com)
- Symptoms of Zika virus infection include rashes, headaches, joint and muscle pain, conjunctivitis and sometimes fever. (infectioncontroltoday.com)
- The cycle of infection is: a mosquito bites a person (or certain animals) that has the virus. (patriotledger.com)
- Although after someone is infected with chikungunya, they seem to develop lifelong immunity (so they cannot get infected a second time), at this time there is no vaccination to prevent a first infection. (patriotledger.com)
- Chikungunya, a viral infection transmitted to humans by infected mosquitoes, originated in southeast Africa and was first described in Tanzania in 1952. (pestworld.org)
- Typical symptoms of Chikungunya infection include the rapid onset of severe joint pains (especially in the hands and feet) and fever. (pestworld.org)
- Since a vaccine to prevent Chikungunya does not exist, it is best to try and avoid infection in the first place. (pestworld.org)
- The current Indian Ocean epidemic and Italian outbreak have featured prominently on Internet infectious disease bulletins, and Chikungunya virus infection had been anticipated in travellers from the outbreak areas. (edu.au)
- BCW's Real-Time Reverse Transcription Polymerase Chain Reaction (RT-PCR) test detects cases in the acute stage of the Chikungunya infection, with results about five hours after the sample has been received. (infectioncontroltoday.com)
- This test will help doctors and health authorities to quickly differentiate Chikungunya infection from other mosquito borne viruses that share the same health symptoms," says Sixto Pacheco, president and CEO of BCW. (infectioncontroltoday.com)
- Chikungunya fever (CHIKF) is an emerging viral infection that has spread widely, along with its Aedes vectors, throughout the tropics and beyond, causing explosive epidemics of acute illness and persistent disabling arthritis. (mdpi.com)
- Is Chikungunya Infection Dangerous? (ms.gov)
- The Mississippi State Department of Health has confirmed a number of cases of chikungunya virus infection in Mississippi residents recently returned from Haiti and the Dominican Republic. (ms.gov)
- If you are sick with the symptoms of chikungunya, or you have been diagnosed with chikungunya infection, you can spread the disease to others through mosquito bites. (ms.gov)
- Do not use this information to diagnose or ayurvedic treatment of allergy-immunity-infection-fever and/or chikungunya without consulting the doctor. (dabur.com)
- While we have products /ayurvedic medicines for allergy-immunity-infection-fever and/or chikungunya, you must consult an authorized physician before taking any of the products. (dabur.com)
- In a first step, a group of researchers including Thomas F. Meyer (Max Planck Institute for Infection Biology) identifed the proteins which the virus absolutely requires for replication in infected human host cells, by using a genome-wide screening. (uni-muenchen.de)
- After an outbreak of Chikungunya infection in Emilia-Romagna Region (North-eastern Italy), a survey was performed to estimate the seroprevalence of antibody to Chikungunya virus and the proportion of asymptomatic infections, to identify factors associated with infection, and evaluate the performance of the surveillance system. (ajtmh.org)
- This study provides basic parameters for modeling the transmission potential of outbreaks and planning control measures for Chikungunya infection in temperate settings. (ajtmh.org)
- We feel we have now identified a fundamental mechanism which the chikungunya virus uses during infection that determines how dangerous the chikungunya infection will be," says study leader Anthony K. L. Leung, PhD, an assistant professor in the Department of Biochemistry and Molecular Biology at the Bloomberg School. (jhsph.edu)
- The results of these studies open a whole new area of investigation into how cells control virus infection and how viruses that cause severe disease can circumvent that control," says Diane E. Griffin, a professor in W. Harry Feinstone Department of Molecular Microbiology and Immunology at the Bloomberg School. (jhsph.edu)
- For the research, Leung, Griffin and their colleagues, using neuronal cells and mouse models, uncovered a fundamental mechanism that determines how dangerous the chikungunya infection will be. (jhsph.edu)
- Without this ability, the virus did not replicate and could not cause an infection. (jhsph.edu)
- This shows us that the virus must break the bond between protein and ADP-ribose to cause infection - which gives us a road map for how to keep infected cells intact and healthy," Leung says. (jhsph.edu)
- Symptoms of virus infection are usually mild, including fever, rash, headache and pain and swelling in the joints. (southeastagnet.com)
- They later tested mosquitoes several days apart to determine how mosquito species and geographic origin may influence infection and how well the mosquitoes may be able to transmit the virus by biting a person. (southeastagnet.com)
- Cases of Chikungunya infection in the US are believed to be transmitted from the Yellow Fever Mosquito, Aedes aegypti, which is common in warmer states like Texas, Louisiana, Mississippi, Alabama, Georgia, and Florida. (trulynolen.com)
Mosquitoes62
- Chikungunya is a virus passed to humans by the bite of infected mosquitoes. (medlineplus.gov)
- This means that mosquitoes in those areas have the virus and are spreading it to humans. (medlineplus.gov)
- Mosquitoes spread the virus to humans. (medlineplus.gov)
- Mosquitoes pick up the virus when they feed on infected people. (medlineplus.gov)
- The mosquitoes that spread chikungunya are the same type that spread dengue fever , which has similar symptoms. (medlineplus.gov)
- The best way to avoid getting the virus is to avoid getting bitten by mosquitoes. (medlineplus.gov)
- If you get chikungunya, try to avoid getting bitten by mosquitoes so you do not pass the virus to others. (medlineplus.gov)
- The virus is transmitted by mosquitoes and belongs to the family Togaviridae in the genus Alphavirus . (medicinenet.com)
- Humans are infected when Aedes aegypti and albopictus mosquitoes, containing Chikungunya virus, bite humans. (medicinenet.com)
- The viruses then multiply in humans and can then be picked up by other uninfected mosquitoes when they bite infected humans to complete the viral replication cycle. (medicinenet.com)
- However, outbreaks can occur in populations where a number of both mosquitoes and humans are infected with the virus. (medicinenet.com)
- Poor people are most at risk because they have less protection from mosquitoes, warns Peter Hotez of Baylor College of Medicine in Houston, Texas, but they are unlikely to be diagnosed with an exotic foreign virus - especially since most doctors do not have a specific test for the virus. (newscientist.com)
- The virus can spread into a new area if an infected person arrives and is then bitten by Aedes mosquitoes. (newscientist.com)
- West Nile virus invaded in 1999 and is now endemic, and tiger mosquitoes recently gave dengue fever to a man in Long Island, New York , the first ever case in the state. (newscientist.com)
- The virus, which is transmitted from mosquitoes to humans and vice versa, has been spreading rapidly through the Caribbean since it was first identified on the island of St. Martin in. (wsj.com)
- There's a concern that people from the United States who go to the Caribbean might be bitten by infected mosquitoes and then bring this illness, this virus, back to the United States,' Dr. Schaffner said. (newsmax.com)
- In the past decade, chikungunya--a virus transmitted by Aedes spp mosquitoes--has re-emerged in Africa, southern and southeastern Asia, and the Indian Ocean Islands as the cause of large outbreaks of human disease. (nih.gov)
- Chikungunya (pronunciation: chik-en-gun-ye) virus is transmitted to people by mosquitoes. (cor.net)
- The virus is spread by bites from infected Aedes mosquitoes. (cor.net)
- Chikungunya virus is spread by mosquitoes. (scidev.net)
- Both cases involved persons infected with the virus following visits to the Caribbean, then both were bitten by uninfected mosquitoes in Florida, which then transmitted the virus further. (rt.com)
- Can Florida Mosquitoes Transmit New Strains of Painful Chikungunya Virus? (newswise.com)
- Researchers want to evaluate the ability of Florida mosquitoes to transmit chikungunya because the virus was transmitted in Florida as part of an outbreak throughout the Americas in 2014. (newswise.com)
- Chikungunya is a febrile viral illness transmitted by mosquitoes. (health.govt.nz)
- The mosquitoes that are able to transmit Chikungunya virus are not normally found in New Zealand, therefore Chikungunya should only be considered in people who have recently travelled overseas. (health.govt.nz)
- The mosquitoes that are able to spread Chikungunya virus are not normally found in New Zealand. (health.govt.nz)
- Researchers led by Jorge Osorio, a UW-Madison professor of pathobiological sciences, and Scott O'Neill of the the Eliminate Dengue Program (EDP) and Monash University in Melbourne, Australia, are already releasing mosquitoes harboring the Wolbachia bacterium in pilot studies in Colombia, Brazil, Australia, Vietnam and Indonesia to help control the spread of dengue virus. (eurekalert.org)
- While not typically found in the Aedes aegypti mosquito -- the species that also transmits dengue, chikungunya and yellow fever viruses -- O'Neill discovered in the early 1990s that Wolbachia could be introduced to the mosquito in the lab and would prevent the mosquitoes from transmitting dengue virus. (eurekalert.org)
- In the study, the team infected mice with Zika virus originally isolated from a human patient and allowed mosquitoes from Medellin to feed on the mice either two or three days after they were infected. (eurekalert.org)
- The mosquitoes were either harboring the same strain of the Wolbachia bacteria (called wMel) used in field studies or were Wolbachia -free and the mice had levels of virus in their blood similar to humans infected with Zika virus. (eurekalert.org)
- An additional group of mosquitoes, both wild-type and Wolbachia -infected, was allowed to feed instead from a membrane containing sheep's blood spiked with a high concentration of Zika virus, per other standard laboratory studies. (eurekalert.org)
- Chikungunya virus is transmitted to people by mosquitoes. (livescience.com)
- This virus is not spread person to person, but rather by the bite of certain mosquitoes. (tbo.com)
- The cases of the virus, transmitted to humans through mosquitoes, have also been confirmed in North Carolina, Nebraska and Indiana. (rt.com)
- Native mosquitoes also can carry the viruses. (baltimoresun.com)
- A virus by the name of chikungunya, which is carried by mosquitoes, has spread to the Americas, appearing in the Carribean, the WHO states. (medicaldaily.com)
- The virus, which is transmitted by mosquitoes, causes a rare form of viral fever. (sciencephoto.com)
- However, the virus is now widespread in the Caribbean and it's likely only a matter of time before it is found in mosquitoes in the United States, possibly as early as this summer, according to the CDC. (cogwriter.com)
- So there is transmission of the virus between people and mosquitoes going on right now in both those locations," she said. (cogwriter.com)
- Aedes mosquitoes transmit chikungunya virus to people. (cogwriter.com)
- Chikungunya virus is spread by mosquitoes and causes severe joint and muscle pain. (brightsurf.com)
- Zika viruses are usually transmitted by Aedes mosquitoes, but can also be trans-mitted sexually. (infectioncontroltoday.com)
- Chikungunya viruses are also transmitted by Aedes mosquitoes and cause symptoms similar to Zika virus infections. (infectioncontroltoday.com)
- Chikungunya (which means "stooped walk" in a Tanzanian language, named because the joint pain from it makes people walk in a bent over fashion) is a viral illness transmitted by infected mosquitoes (only certain types of mosquitoes can carry this virus). (patriotledger.com)
- although I am unaware of any cases transmitted from infected mosquitoes within the U.S., the types of mosquitoes that can carry this virus do exist here, so it is likely just a matter of time until there are cases of chikungunya acquired within the U.S. borders. (patriotledger.com)
- however, other diseases, such as dengue fever, may have similar symptoms (and indeed dengue fever may be transmitted by the same types of mosquitoes and in the same geographic areas as chikungunya), so definitive diagnosis may be challenging. (patriotledger.com)
- Finally, patients who are diagnosed with Chikungunya should avoid additional exposure to mosquitoes to help prevent the further spread of the virus to other mosquitoes and subsequently to other people. (pestworld.org)
- The virus is spread through a variety of mosquitoes called Aedes Aegypti and Aedes Albopictus, said Weber-Morgan Health Department public relations director Lori Buttars. (revolutionradio.org)
- Unlike West Nile virus, these mosquitoes are daytime biters. (revolutionradio.org)
- Mosquitoes that carry chikungunya virus are mainly active in the daytime, but mosquitoes that are active toward dawn and dusk can carry other diseases, such as West Nile virus. (ms.gov)
- The virus is transmitted to people by mosquitoes, with the most common symptoms being fever and joint pain, and other symptoms including headache, muscle pain, joint swelling, or rash. (revolutionradio.org)
- The Centre said there was a risk the virus could spread in Europe if infected patients were bitten by mosquitoes upon their return home and those mosquitoes then infected other people. (repeatingislands.com)
- Chikungunya is an RNA viral disease, transmitted to humans by infected Aedes aegypti or Aedes albopictus mosquitoes. (aimsciences.org)
- A global sensitivity analysis using the reproduction number indicates that the mosquito biting rate, the transmission probability per contact of mosquitoes and of humans, mosquito recruitment rate and the death rate of the mosquitoes are the parameters with the most influence on Chikungunya transmission dynamics. (aimsciences.org)
- Furthermore, the disease is spread by the same mosquitoes that transmit the dengue and Zika viruses. (jhsph.edu)
- Chikungunya: the specific interactions between the genotypes of mosquitoes and viruses have influenced Ae. (pasteur.fr)
- Thus, the specific interactions between the genotypes of mosquitoes and viruses have influenced Ae. (pasteur.fr)
- Yellow fever and Asian tiger mosquitoes from Florida and Brazil can transmit an Asian strain of chikungunya virus that's emerging in North, South and Central America, a University of Florida scientist says. (southeastagnet.com)
- In the study, researchers from Oswaldo Cruz Institute in Rio de Janeiro and UF/IFAS compared the abilities of yellow fever and Asian tiger mosquitoes from Brazil and Florida to transmit an emergent Asian strain of chikungunya virus present in North, South and Central America, Alto said. (southeastagnet.com)
- Scientists conducted a laboratory experiment that let groups of mosquitoes eat chikungunya virus- infected blood. (southeastagnet.com)
- However, mosquitoes are known to carry and transmit various viruses such as the deadly West Nile Virus, which has claimed the lives of 66 people since it was first discovered in the United States. (trulynolen.com)
- A substantial proportion of mosquitoes became saliva-positive for both viruses (12%), suggesting that Ae. (wur.nl)
Fever45
- Phylogenetic relationships among chikungunya virus isolates from cases of chikungunya fever in France, based on complete E2-6K-E1 nucleotide sequence (2,771 nt) analysis. (nih.gov)
- Other famous examples include the West Nile virus and dengue fever. (businessinsider.com)
- Chikungunya causes a rash, fever, and excruciating joint pain that last from five to seven days. (webpronews.com)
- Take pain relievers and fever reducers and just let the virus run its course, because there is no cure. (webpronews.com)
- The chikungunya virus - or 'chik-v' - causes high fever and severe pain, and there is no vaccine to prevent it, CBS News reports. (newsmax.com)
- The chikungunya fever will last for three, four, five days. (newsmax.com)
- The chikungunya virus causes fever and debilitating joint pain, and until recently was found only in Africa and Southeast Asia. (livescience.com)
- People infected with chikungunya virus experience fever and joint pain, and may develop muscle aches, headaches, joint swelling or rashes. (livescience.com)
- GBS is a rare neurological complication which may occur after subsidence of fever and constitutional symptoms by several neurotropic viruses. (springer.com)
- Tilak R, Ray S, Tilak VW, Mukherji S (2016) Dengue, chikungunya and the missing entity-Zika fever: a new emerging threat. (springer.com)
- tients suspected to have chikungunya fever manifesting with symptoms such as fever, rash, and arthralgia. (cdc.gov)
- Previous studies persons suspected to have chikungunya within 5 days after of chikungunya fever in the Philippines focused on clini- symptom onset. (cdc.gov)
- Chikungunya, a virus more commonly found in Africa and Asia and transmitted by the aedes aegypti mosquito that causes dengue fever, was first detected in the eastern Caribbean at the start of 2014. (foxnews.com)
- However, it remains unclear with residences served by unpaved streets, a presump- whether the attack rates in outbreaks in large popu- tive clinical diagnosis of chikungunya, and recall of an epi- lation centers in the Americas created sufficiently sode of fever with arthralgia in 2015-2016. (cdc.gov)
- No specific antiviral treatment is available for Chikungunya fever. (medscape.com)
- It is important to exclude other serious infections similar to Chikungunya fever such as dengue, malaria, or bacterial infections. (medscape.com)
- People with suspected Chikungunya fever should avoid mosquito exposure during the first week of viremia to prevent local transmission of the illness. (medscape.com)
- Chikungunya fever is an emerging global disease with several intriguing and unanswered questions such as the reason for sudden major rapid outbreaks with disease-free intervals, mode of survival or maintenance of the virus in nature between epidemics, factors that trigger the outbreaks, and strain replacements during outbreaks. (medscape.com)
- Update: chikungunya fever diagnosed among international travelers--United States, 2006. (medscape.com)
- Chikungunya fever in the United States: a fifteen year review of cases. (medscape.com)
- The virus results in high fever for up to five days and a longer period of severe joint pain in the extremities that renders patients largely immobile. (rt.com)
- The virus causes chikungunya fever - a painful condition whose symptoms include joint pain and swelling, headache, muscle pain or rash and in some instances, chronic rheumatoid arthritis that last for months to years. (newswise.com)
- Between 2014 and 2016, more than 3,800 imported human cases of chikungunya fever in Florida highlighted the risk of contracting the illness, according to the new UF/IFAS study. (newswise.com)
- CDC officials believe Chikungunya will behave like dengue fever, which has seen sporadic cases but not widespread outbreaks. (longislandpress.com)
- Catching the mosquito-borne virus chikungunya usually leads to fever and severe pain, but a new study shows it may also lead to inflammation in the brain, and even death in some people. (livescience.com)
- People who catch the virus are typically treated with fever-reducing medications and painkillers, Gérardin told Live Science. (livescience.com)
- The most common signs of the virus are fever and joint pain, typically in multiple different joints. (foxnews.com)
- That is raising concern over the possible spread of the virus, which is not usually fatal but can cause fever and debilitating joint pain and cannot be treated. (baltimoresun.com)
- Experts with the federal Centers for Disease Control and Prevention said they believe chikungunya will behave similarly to dengue fever in the United States, with cases imported from other parts of the world causing sporadic local transmission but no major outbreaks. (baltimoresun.com)
- Most people who contract West Nile virus, meanwhile, do not develop symptoms, but those who do typically develop a combination of fever, headache, body aches, skin rash and swollen lymph glands. (baltimoresun.com)
- Symptoms of chikungunya - fever, nausea and severe pain, mainly in the joints - can persist for months, according to the WHO, Pravada.Ru notes (2/28). (kff.org)
- Cummulative Number of Reported Cases of Chikungunya Fever in the Americas, by Country or Territory 2014. (eurosurveillance.org)
- Although chikungunya fever is rarely fatal, patients can experience debilitating symptoms that last from months to years. (eurosurveillance.org)
- Because there is no specific antiviral drug treatment for Chikungunya, physicians direct patients to use over the counter analgesics and medication to control fever, and to get plenty of rest and fluids. (pestworld.org)
- Chikungunya (CHIK) fever is a re-emerging Aedes mosquito-transmitted viral disease caused by CHIK virus belonging to the Togaviridae family of genus Alphavirus. (infectioncontroltoday.com)
- Like many other arboviral diseases, chikungunya fever (CHIKF) is transmitted by mosquito vectors, primarily Aedes aegypti and Aedes albopictus [ 3 ]. (mdpi.com)
- There is currently no vaccine or medication to prevent chikungunya fever. (revolutionradio.org)
- Chikungunya virus causes fever, muscle and joint pain, and swelling of the joints. (ms.gov)
- If you develop symptoms of fever and joint pain within 14 days of traveling from countries in the Caribbean or other countries with known local transmission of chikungunya virus, you should see your healthcare provider and mention your recent travel. (ms.gov)
- Chikungunya produces symptoms similar to dengue , including high fever, joint pain and skin rash. (medicalxpress.com)
- The Health Department in American Samoa says it has confirmed the acute rash outbreak as cases of Chikungunya, a virus similar to dengue fever. (revolutionradio.org)
- There is currently no vaccine or treatment for the mosquito-born virus which resembles dengue fever and can cause fever, skin rash and joint pain. (repeatingislands.com)
- The Dengue fever is spread due to the bite of an infected Aedes aegypti mosquito infected with Dengue virus. (dabur.com)
- People can get the chikungunya virus if they're bitten by an infected yellow fever mosquito, also known as Aedes aegypti or the Asian tiger mosquito, known as Aedes albopictus , said Alto, a faculty member at the UF/IFAS Florida Medical Entomology Laboratory in Vero Beach, Florida. (southeastagnet.com)
- Since 2015, both viruses circulate in the same geographical regions of the Americas and are predominantly transmitted by the Yellow Fever mosquito Ae. (wur.nl)
Outbreaks10
- However, ten years back, a novel form of the virus emerged in coastal Kenya, which then spread to countries around the Indian Ocean, including India, causing huge outbreaks. (thehindu.com)
- Whereas mosquito-based surveillance is the preferred method for monitoring or predicting West Nile virus outbreaks, it is not the preferred method for monitoring or predicting Chikungunya outbreaks. (cor.net)
- Newswise - GAINESVILLE, Fla. --- University of Florida scientists are starting to better understand the ability of two Florida mosquito species to transmit two strains of chikungunya virus that have caused outbreaks of human disease around the world. (newswise.com)
- Outbreaks of chikungunya have occurred in many regions of the world, including Africa, Asia, and the Caribbean islands, the researchers said. (livescience.com)
- Now that chikungunya is in the United States, CDC officials think it will behave like dengue virus, with imported cases causing occasional local transmissions but not widespread outbreaks. (tbo.com)
- Millions of people have contracted Zika and chikungunya virus infections since the outbreaks that have been striking Latin America since 2013. (infectioncontroltoday.com)
- It is thought that most people infected with chikungunya develop symptoms within two days to two weeks after the virus is transmitted from the bite of an infected mosquito, although some studies after outbreaks in Africa have shown that up to 50 percent of people who were infected, as demonstrated by antibodies to the virus in their blood tests, did not report any symptoms. (patriotledger.com)
- During outbreaks of Chikungunya - or if mosquito populations surge - community-wide insect/vector control programs may be activated and travelers should heed these warnings. (pestworld.org)
- Prior to 2013, chikungunya virus outbreaks had been identified in countries in Africa, Asia, Europe and the Indian and Pacific Oceans. (jhsph.edu)
- Our findings suggest that mosquito-virus interactions of both these mosquito species may vary by geographic population - whether that's in Brazil or Florida - which may impact public health measures and should be considered during outbreaks of this mosquito-borne disease," said Honório. (southeastagnet.com)
Alphavirus3
- We extracted virus (family Togaviridae , genus Alphavirus ). (cdc.gov)
- Chikungunya virus was diagnosed by performing a generic alphavirus reverse transcriptase polymerase chain reaction (RT-PCR) on serum. (mja.com.au)
- Blood taken at admission was positive for alphavirus RT-PCR, and sequencing confirmed Chikungunya virus. (mja.com.au)
Endemic6
- The virus is endemic to tropical regions, but the spread of Aedes albopictus into Europe and the Americas coupled with high viraemia in infected travellers returning from endemic areas increases the risk that this virus could establish itself in new endemic regions. (nih.gov)
- The findings indicated that even more efficient chikungunya virus transmission by A. albopictus "will likely evolve when combinations of these second-step mutations occur in their current ranges of endemic circulation in India and Southeast Asia, followed by their likely global spread," the scientists noted in the paper. (thehindu.com)
- Should a super-adapted strain arise, rising levels of immunity to chikungunya in regions where it is endemic might prevent an increase in disease incidence in the local population, said Dr. Weaver in an email. (thehindu.com)
- Chikungunya has been endemic in parts of Africa for a long time. (patriotledger.com)
- Rather, travelers are advised to take a number of precautions when staying in countries where Chikungunya is endemic. (pestworld.org)
- The resulting virus fails to replicate in its mosquito vector, an important safety feature when immunizing travelers or laboratory personnel in non-endemic locations. (fiercebiotech.com)
Infections15
- As of December 2014, 41 countries or territories in the Caribbean, Central America, South America and North America have had laboratory-confirmed Chikungunya infections. (medicinenet.com)
- How do health care professionals diagnose Chikungunya virus infections? (medicinenet.com)
- The best way to prevent Chikungunya infections is to avoid getting mosquito bites. (rxlist.com)
- Two new studies explore strategies that could offer relief from the debilitating joint pain caused by Chikungunya virus infections, an emerging disease with no known therapies. (eurekalert.org)
- Lewthwaite P, Vasanthapuram R, Osborne JC et al (2009) Chikungunya virus and central nervous system infections in children, India. (springer.com)
- Health officials in Florida also reported the first domestically acquired chikungunya infections in the United States. (rt.com)
- News of the local residents' infections came last week shortly after the U.S. Centers for Disease Control and Prevention (CDC) confirmed the first case of Chikungunya to be contracted within the continental United States, in Florida. (longislandpress.com)
- Given the conservation of viral macrodomains in all alphaviruses and coronaviruses, our study may guide the design of small molecule chemical compounds that block hydrolase activity for treatment of a range of virus infections. (pnas.org)
- This virus is also widespread in Latin America and can cause symptoms similar to those of Zika infections but presumably does not cause malformations. (infectioncontroltoday.com)
- Subsequently, infections can solely be confirmed by detecting the antibodies against the virus produced by the infected individual. (infectioncontroltoday.com)
- However, vaccinations and infections with similar viruses hamper precise antibody detection. (infectioncontroltoday.com)
- Patients with confirmed Zika or chikungunya virus infections were included in the study. (infectioncontroltoday.com)
- In Zika virus infections, the virus concentration is already so low in the first week that particularly sensitive testing is required and combined antibody testing should be done. (infectioncontroltoday.com)
- We can see very clearly that a combination of several testing procedures must be used to obtain precise Zika virus test results, particularly in tropical regions where people contract infections with many viruses that are related to each other,' Drexler concludes. (infectioncontroltoday.com)
- Prompt diagnosis of Chikungunya virus infections is of public health significance as the mosquito vectors for transmission exist in Australia. (edu.au)
Outbreak of chikungunya3
- In 2004, an outbreak of chikungunya disease started in Kenya and spread to islands in the Indian Ocean and finally India, where it had not been reported for 32 years. (virology.ws)
- Ledrans M, Quatresous I, Renault P, Pierre V. Outbreak of chikungunya in the French Territories, 2006: lessons learned. (eurosurveillance.org)
- There has been a recent outbreak of Chikungunya, a mosquito-borne disease prevalent in India and Southeastern Asia. (trulynolen.com)
Epidemic12
- Differing epidemiological dynamics of Chikungunya virus in the Americas during the 2014-2015 epidemic. (jcvi.org)
- Puerto Rican health officials declared Thursday an epidemic of chikungunya, a mosquito-borne virus that has shown up in more than 200 confirmed cases across the island as of late last month. (rt.com)
- In the study, researchers looked at an epidemic of the virus on Reunion Island, in the Indian Ocean near Madagascar, that lasted from 2005 to 2006 and sickened 300,000 people. (livescience.com)
- As clinicians became aware of the Indian Ocean epidemic, unwell travellers returning from affected countries were tested for Chikungunya virus. (mja.com.au)
- Our observation that a single amino acid substitution can influence vector specificity provides a plausible explanation of how this mutant virus caused an epidemic in a region lacking the typical vector. (nih.gov)
- The risk of autochthonous transmission of chikungunya virus becoming established in Spain may be elevated due to the large numbers of travellers returning to Spain from countries affected by the 2013 epidemic in the Caribbean and South America, as well as the existence of the Aedes albopictus vector in certain parts of Spain. (eurosurveillance.org)
- Chikungunya: Evolutionary history and recent epidemic spread. (eurosurveillance.org)
- The virus: isolation, pathogenic properties and relationship to the epidemic. (eurosurveillance.org)
- In 2015-2016 in the Recife Metropolitan Region, we detected the tail end of a Zika epidemic, which was displaced by a chikungunya epidemic. (unboundmedicine.com)
- This information is essential to better estimate the risks of chikungunya emergence, specifying the strong genetic proximity of the mosquito in South-East France with that of La Reunion Island, where the largest chikungunya epidemic ever occurred in France, and more generally in Europe. (pasteur.fr)
- Chikungunya is an epidemic disease in Brazil and a potential risk in Florida," Alto said. (southeastagnet.com)
- Nearly 250 people have contracted the virus in Puerto Rico, where health officials have declared an epidemic. (travelagentcentral.com)
Antibody5
- Corroborating these results further, Jonathan Miner and colleagues found that the rheumatoid arthritis drug Abatacept (which hinders T cell activation in the lymph nodes) decreased inflammation in the joints of infected mice, and abolished arthritis completely when given in combination with an antibody targeting the virus. (eurekalert.org)
- Available diagnostic tests are aimed at detection of the virus, its antigenic components, or the host immune antibody response. (hindawi.com)
- Transplacental chikungunya virus antibody kinetics, Thailand. (thefreelibrary.com)
- Each Chikungunya virus Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. (novusbio.com)
- Chikungunya Virus Monoclonal antibody specifically detects Chikungunya Virus in Virus samples. (fishersci.com)
Chik-en-gun-ye1
- The name chikungunya (pronounced "chik-en-gun-ye") is an African word meaning "bent over in pain. (medlineplus.gov)
Florida15
- MIAMI-Public health officials in Florida said Thursday that two people in the state contracted the mosquito-borne chikungunya virus locally, the first confirmed cases in which the disease was acquired in the continental U.S. rather than overseas. (wsj.com)
- Cases of the virus have turned up in New York, Florida, and other states, according to the CDC. (newsmax.com)
- Scientists confirmed the first case of chikungunya in Florida in 2014. (newswise.com)
- Transmission of chikungunya virus in the U.S. is a major public health concern," said Alto, a faculty member at the UF/IFAS Florida Medical Entomology Laboratory in Vero Beach, Florida. (newswise.com)
- In 2014, a Florida man became the first person to become infected with the virus in the U.S. (previously, other people had been diagnosed with chikungunya in the U.S., but they had contracted the virus while traveling elsewhere). (livescience.com)
- In both, they said, a person infected with the virus after visiting the Caribbean was then bitten again by an uninfected mosquito in Florida, which then transmitted the illness further. (tbo.com)
- Florida has been the worst hit by the virus, with at least 25 cases reported in the state, according to the US Centers for Disease Control and Prevention. (rt.com)
- The Florida Department of Health released a set of guidelines in order to avoid becoming infected and spreading the virus. (rt.com)
- State health officials are urging Marylanders to be wary of mosquito-borne diseases like West Nile virus and, now, the dengue-like virus chikungunya - raising concerns after it was reported in a Florida man Thursday. (baltimoresun.com)
- Just one week after health officials warned Florida inhabitants of the mosquito-borne virus chikungunya spreading through their state, several more states have reported cases of the disease. (medicaldaily.com)
- So far, Florida has experienced 25 cases, but North Carolina, Nebraska, and Indiana have all confirmed several chikungunya cases this week. (medicaldaily.com)
- The Asian strain of the virus is not currently circulating in Florida, and Barry Alto, associate professor of entomology at the UF Institute of Food and Agricultural Sciences, said that he can't predict whether it will cause local transmission in the Sunshine State this year. (southeastagnet.com)
- That year, scientists confirmed the first case of chikungunya in Florida. (southeastagnet.com)
- The mosquito-borne virus has spread through the Caribbean, and the first two cases in the United Stated were reported last week in Florida. (travelagentcentral.com)
- Specifically, we identified multiple introductions in both Nicaragua and Florida, with rapid local spread of viruses in Nicaragua but limited autochthonous transmission in Florida in the US. (jcvi.org)
Pathogenesis3
- This Seminar focuses on the re-emergence of this disease, the clinical manifestations, pathogenesis of virus-induced arthralgia, diagnostic techniques, and various treatment modalities. (nih.gov)
- Chikungunya virus pathogenesis: From bedside to bench. (archives-ouvertes.fr)
- Chikungunya in Infants and Children: Is Pathogenesis Increasing? (mdpi.com)
Travelers11
- There is a risk that the virus will be imported to new areas by infected travelers. (cdc.gov)
- Travelers to those countries where Chikungunya is prevalent are advised to use mosquito repellent with DEET and to wear long sleeves and pants. (webpronews.com)
- An average of 28 cases Chikungunya had been reported annually in the nation from 2006 to '13, mostly from travelers returning from Asia. (longislandpress.com)
- But, the spike in Chikungunya-infected travelers entering the nation increases the chances of local transmission. (longislandpress.com)
- More than 230 chikungunya cases have been reported in Americans this year, but all the others were travelers believed to have been infected elsewhere. (tbo.com)
- They involve travelers who returned from the Dominican Republic on May 17 and May 29, said state officials, adding that authorities are currently investigating several other suspicious cases of the virus. (rt.com)
- Given the amount of U.S. travelers who vacation on these tropical islands each year, health experts believe chikungunya will soon spread beyond the Caribbean Sea, setting up shop in its neighboring continents. (foxnews.com)
- Cases of chikungunya have been reported in travelers returning to the US, although transmission within the country has not been reported. (virology.ws)
- Chikungunya virus is a mosquito-borne disease especially prevalent in the Caribbean, where it can infect U.S. travelers. (ms.gov)
- Chikungunya can spread from person to person through the bite of a mosquito once travelers return home. (ms.gov)
- U.S. travelers contracted the virus in tropical destinations including Anguilla , the Dominican Republic , Guyana, Haiti , Indonesia, Tonga and the U.S. Virgin Islands , according to the Centers for Disease Control and Prevention. (travelagentcentral.com)
Transmission13
- In September 2010, autochthonous transmission of chikungunya virus was recorded in southeastern France, where the Aedes albopictus mosquito vector is present. (nih.gov)
- The ease with which people travel will make it difficult to break the continuing transmission of chikungunya, warns Hervé Zeller, head of emerging diseases at ECDC. (newscientist.com)
- Chikungunya virus is a mosquito-borne illness that has rapidly spread throughout the Americas, with more than 1.7 million suspected cases since the first incidence of local transmission was detected in the Caribbean in 2013. (eurekalert.org)
- The chikungunya virus circulating in parts of India as well as Sri Lanka and South-East Asia could gain the ability to spread more efficiently by combining mutations, becoming 'super-adapted' for transmission by the Asian tiger mosquito, Aedes albopictus , according to research published recently. (thehindu.com)
- Samples were collected from pa- the transmission pattern of this virus in the Philippines. (cdc.gov)
- Alto views the new findings as useful measurements that can be used in risk assessment by scientists as they model chikungunya transmission. (newswise.com)
- Researchers at the University of Wisconsin-Madison have confirmed that a benign bacterium called Wolbachia pipientis can completely block transmission of Zika virus in Aedes aegypti , the mosquito species responsible for passing the virus to humans. (eurekalert.org)
- But it all changed in 2013, when health experts found that sustained transmission of the chikungunya virus had occurred in the Caribbean, meaning people on the islands were starting to become infected by local mosquitos. (foxnews.com)
- The Pan-American Health Organization (PAHO), a regional arm of the World Health Organization (WHO), on Tuesday "unveiled new guidelines to help countries throughout the Americas detect and prevent transmission of the mosquito-borne chikungunya virus - a disease which has already infected more than two million people around the world," the U.N. News Centre reports. (kff.org)
- This has important implications with respect to how viruses may establish a transmission cycle when introduced into a new area. (nih.gov)
- This is the first time that locally acquired transmission of chikungunya has been detected in the WHO Americas Region," the WHO said in a statement . (medicaldaily.com)
- Coloured transmission electron micrograph (TEM) of chikungunya virus particles (yellow). (sciencephoto.com)
- In this paper, an age-structured deterministic model for the transmission dynamics of Chikungunya virus is presented. (aimsciences.org)
Transmit2
- We have the kind of mosquito that will transmit this virus here in the U.S. (newsmax.com)
- In a newly published study led by Brazilian scientist Nildimar Honório of the Oswaldo Cruz Institute, Alto helped assess the ability of the two mosquito species to transmit chikungunya. (southeastagnet.com)
Americas14
- In late 2013, chikungunya virus was found for the first time in the Americas on islands in the Caribbean. (cdc.gov)
- Although Chikungunya virus has been mainly reported in Africa, Asia, Europe, and the islands in the Indian and Pacific oceans, it has spread to the Americas recently. (medicinenet.com)
- It is the first time the mosquito-borne virus is known to have spread in the Americas. (newscientist.com)
- In the Americas, only Brazil, Canada, the US and the French territories of French Guiana, Guadeloupe and Martinique have the capability to test for the virus, says Donna Eberwine-Villagrán of PAHO. (newscientist.com)
- But "controlling the spread of [insect-borne] viruses in the Americas has not been very successful," admits PAHO in its chikungunya response report. (newscientist.com)
- The U.S. Defense Advanced Research Projects Agency, or DARPA, is challenging innovators to build models to predict how the mosquito-borne chikungunya virus could spread across countries in the Americas. (livescience.com)
- But since last year, the virus has spread to the Americas, and has infected thousands of people in the Caribbean. (livescience.com)
- There is no commercial vaccine for the virus, which was detected for the first time in the Americas late last year. (foxnews.com)
- Chikungunya has been identified in nearly 40 countries in Asia, Africa, Europe and the Americas. (health.govt.nz)
- The arrival of chikungunya virus, first in the tropical Americas and now in the United States, underscores the risks posed by this and other exotic pathogens," said Roger Nasci, of the Centers for Disease Control and Prevention, in a prepared statement. (tbo.com)
- According to WHO, Chikungunya was first described during an outbreak in southern Tanzania in 1952, eastern Africa, and since then has been detected in nearly 40 countries in Asia, Africa, Europe and also in the Americas. (rt.com)
- The guidelines' authors, PAHO adviser on viral diseases Otavio Oliva and PAHO adviser on dengue Jose Luis San Martin, warned that the fact that people in the Americas have not been exposed to chikungunya virus, placed the region at particular risk for the introduction and spread of the virus," the news service adds (2/28). (kff.org)
- But since 2013, chikungunya, which is debilitating but rarely fatal, has been detected throughout the Americas, with more than 1.7 million suspected cases in this region alone. (jhsph.edu)
- Chikungunya is a virus of the Togaviridae family which has affected different parts of the world on several occasions: 2004 in the Indian Ocean, 2007 in Africa, 2007 in Europe, 2011 in the Pacific region, and 2013 in the Americas. (pasteur.fr)
Rash2
- Chikungunya disease is characterized by polyarthralgia, sometimes associated with rash. (plos.org)
- Like any viral syndrome, chikungunya can also cause muscle aches, headaches, rash and joint swelling. (foxnews.com)
Immunity2
Rarely fatal5
- The virus is rarely fatal, according to health officials. (rt.com)
- The rarely fatal virus causes symptoms such as severe fevers, arthritic-like joint paint, muscle pain, headaches, joint swelling and rashes. (longislandpress.com)
- Chikungunya virus is rarely fatal. (tbo.com)
- Chikungunya is rarely fatal and typically spread to humans through mosquito bites. (medicaldaily.com)
- Although Chikungunya is rarely fatal, symptoms of the illness include high fevers in excess of 102 °F, severe headaches, nausea, vomiting, conjunctivitis, and severe joint pain that typically lasting for about two weeks. (trulynolen.com)
Acute2
- This study demonstrates that chronic arthralgia is a frequent complication of acute Chikungunya disease and suggests that it results from a local rather than systemic inflammation. (plos.org)
- Chikungunya disease is characterized by acute transient febrile arthralgic illness, but can also lead to chronic incapacitating arthralgia. (plos.org)
Viral disease3
- Mexico has detected its first domestic case of the painful mosquito-borne viral disease chikungunya in the southwest of the country, the state government of Chiapas said on Saturday. (foxnews.com)
- Using this approach, a group from the UMR_D 190, Emerging viruses Department in Marseille, France in collaboration with the University of Sydney, Australia, showed that the engineered viruses exhibit a stable phenotype with a significantly decreased viral fitness (i.e., replication capacity), making it a new vaccine candidate for the emerging viral disease. (medindia.net)
- Health Minister Violeta Menjivar said at least 1,200 people have been formally diagnosed with the chikungunya viral disease, although the positive testing must still be confirmed by the US Centers for Disease Control and Prevention. (medicalxpress.com)
Replication7
- Some time during 2005 a virus was selected with a single amino acid change in the envelope glycoprotein which allows efficient replication in Aedes albopictus, the predominant mosquito in Réunion. (virology.ws)
- The amino acid change enhances viral replication in the mosquito, leading to much higher levels of virus in the salivary gland. (virology.ws)
- For this purpose, the researchers switched off each individual gene of the human cells in a complex automated process, infected the modified cells, and then analyzed the extent of virus replication. (uni-muenchen.de)
- This enabled them to identify more than 100 human proteins that are essential for the replication of the virus. (uni-muenchen.de)
- In cooperation with virologists including Marc Lecuit of the Institut Pasteur (Paris), as well as researchers from the Charité and the Steinbeis Innovation Center in Berlin, the Institute of Technology in Tartu, Estonia, and Bracher's research group at the Department of Pharmacy, the scientists identified the substances which can control these important human proteins and thus inhibit the replication of the virus. (uni-muenchen.de)
- Another study published in the journal Emerging Infectious Diseases showed that the turmeric compound decreased viral replication by more than 90 percent in cultured cells infected with influenza-A. The compound was also found to inhibit the virus from infecting other cells. (naturalnews.com)
- Another study by McMaster University researchers revealed that the turmeric compound stopped both simplex-1 and herpes simplex-2 viruses from spreading by preventing the replication of the viruses in infected T-cells. (naturalnews.com)
Caribbean25
- In 2013 the virus had spread to the Caribbean islands. (medicinenet.com)
- A dozen people on the tiny Caribbean island of St Martin have been infected with the chikungunya virus. (newscientist.com)
- The virus was first recorded in 1952 in Africa then Asia, but in 2013 it began to spread to the Caribbean and Haiti. (webpronews.com)
- Most chikungunya patients in the United States were infected when traveling in the Caribbean, but four Americans have caught the virus inside this country . (livescience.com)
- Chikungunya has already appeared in much of the Caribbean, Central America and the United States. (foxnews.com)
- The virus was introduced into the Caribbean region late last year, according to AP. (rt.com)
- As of July 11, the Pan American Health Organization recorded more than 354,000 suspected and confirmed cases of chikungunya across the Caribbean. (rt.com)
- The chikungunya virus, a mosquito-borne illness that causes high fevers and sometimes intense pain, is spreading rapidly throughout the Caribbean. (foxnews.com)
- Now the virus is widespread, with up to 17 different countries in the Caribbean reporting cases of the disease. (foxnews.com)
- The virus spread quickly through the Caribbean, starting on the French side of the island of Saint Martin, and into South and Central America late last year. (baltimoresun.com)
- Chikungunya outbreak in the Caribbean region, December 2013 to March 2014, and the significance for Europe. (eurosurveillance.org)
- An African mosquito-bred virus by the name of "chikungunya" has been confirmed in two cases in the French part of the Caribbean isle of Saint Martin, located off the eastern coast of Puerto Rico, and situated between North and South America. (medicaldaily.com)
- Chikungunya - which triggers a very painful but seldom fatal illness - is already common in central and southern Africa, southern Asia and has recently spread to 17 countries in the Caribbean, the CDC noted. (cogwriter.com)
- More recently, Chikungunya has been reported in at least 15 Caribbean islands, including Hispaniola (Haiti & Santo Domingo), as well as French Guiana on mainland South America. (pestworld.org)
- Chikungunya, once confined to Africa and Asia, is now prevalent in the Caribbean and bordering countries in South and Central America, including Haiti and the Honduras. (ms.gov)
- Mississippians who travel to the Dominican Republic, Haiti, Puerto Rico or other Caribbean countries are at risk of chikungunya virus. (ms.gov)
- Cases of chikungunya have occurred on the Caribbean island of Saint Martin, marking the first time the mosquito-borne disease has spread in the western hemisphere, the World Health Organisation (WHO) said on Tuesday. (medicalxpress.com)
- A mosquito-borne virus that was detected for the first time in Haiti last week has quickly spread throughout the Caribbean nation, a health official said Tuesday. (medicalxpress.com)
- A nasty mosquito-borne virus that has been spreading rapidly in the Caribbean has made its way to the U.S. Virgin Islands, authorities said Wednesday. (medicalxpress.com)
- The number of suspected and confirmed cases of chikungunya virus in Caribbean countries has risen sharply over past weeks, health officials say. (repeatingislands.com)
- According to Karen Weintraub ( National Geographic ) Chikungunya has plagued other parts of the world-particularly Asia and Africa-for decades, becoming more prevalent in recent years, but it arrived in the Caribbean only in December and has already infected as many as 250,000 people there. (repeatingislands.com)
- Most of the chikungunya cases have occurred in the Caribbean islands, Africa, and East Asia, and now that they've arrived in the U.S., the CDC is concerned about an outbreak here. (medicaldaily.com)
- So far this year we've recorded eight travel-associated cases, and seven of them have come from countries in the Caribbean, where we know the virus is being transmitted," Roger Nasci, chief of the CDC's Arboviral Disease Branch in the Division of Vector-Borne Diseases, told CNN . (medicaldaily.com)
- The chikungunya virus , the mysterious mosquito-borne virus first discovered in the Caribbean on the sister islands of St. Maarten/St. Martin, is continuing to spread throughout the United States with recent news that 25 New Jersey residents have tested positive for the virus following a Caribbean vacation. (travelagentcentral.com)
- On Wednesday, stltoday.com reported that a 38-year-old St. Louis County woman was infected with the mosquito-borne virus chikungunya while traveling in the Caribbean. (travelagentcentral.com)
Humans3
- The mutation, known as 'E2-L210Q,' further enhanced the virus' ability to replicate in the A. albopictus mosquito and thereby increase its circulation among humans. (thehindu.com)
- Alphaviruses are arthropod-transmitted RNA viruses that can cause arthralgia, myalgia, and encephalitis in humans. (asm.org)
- The virus is spread to humans through mosquito bites, and it causes symptoms of splitting headaches, high fevers, and aching joints. (medicaldaily.com)
Disease20
- For the most up-to-date information, please visit the Centers for Disease Control and Prevention's (CDC) website -- www.cdc.gov/chikungunya . (medlineplus.gov)
- Chikungunya virus disease became a nationally notifiable condition in 2015. (cdc.gov)
- A new mosquito-borne virus that has sickened tens of thousands of people throughout the Carribbean is now threatening the U.S., with cases confirmed in 15 states, the Centers for Disease Control and Prevention Reports. (newsmax.com)
- This is an infographic describing the disease burden of Chikungunya virus. (eurekalert.org)
- Infected patients are at-risk for long-term joint stiffness and pain, which increases the need to better understand the sequence diversity of these viruses and how any viral mutations affect the severity of disease in the human host. (jcvi.org)
- This year, 571 cases of chikungunya virus disease have been reported so far in 42 U.S. states, including cases contracted both here and elsewhere. (livescience.com)
- "It will be more difficult for the virus to establish itself here," Dr. William Schaffner, an infectious disease specialist at Vanderbilt University Medical Center in Nashville, Tennessee told Tech Times. (rt.com)
- 1 Chikungunya is believed to be derived from an East African dialect describing the contorted posture of patients with the severe joint pain characteristic of this disease. (virology.ws)
- Weaver SC , Lecuit M . Chikungunya virus and the global spread of a mosquito-borne disease. (eurosurveillance.org)
- Chikungunya disease does not often result in death, but its symptoms can be severe and disabling, officials said. (cogwriter.com)
- According to the Centers for Disease Control and Prevention (CDC), as of June 10, a total of 39 chikungunya cases have been reported from U.S. states and territories. (pestworld.org)
- During the recent outbreak the virus was also found to cause long-term joint pain, severe neurological disease and even fatalities. (infectioncontroltoday.com)
- According to the Center for Disease Control and Prevention (CDC), as of Dec. 16, 2014 a total of 2,021 Chikungunya virus disease cases have been reported in the United States. (infectioncontroltoday.com)
- There is no vaccine or treatment for chikungunya , which has infected millions of people in Africa and Asia since the disease was first recorded in 1952. (medicalxpress.com)
- The Centers for Disease Control and Prevention (CDC) will be monitoring the spread of the virus in various states this summer, specifically in Nevada, New York, California, Arkansas, Maryland, Connecticut, Minnesota, Virginia, Puerto Rico and the U.S. Virgin Islands. (medicaldaily.com)
- Researchers led by the Johns Hopkins Bloomberg School of Public Health have identified a mechanism by which the chikungunya virus infects healthy cells and controls how severe the disease it causes will be, a mechanism they believe can be found in a number of other related viruses for which there are no treatments or licensed vaccines. (jhsph.edu)
- This mechanism depends on a class of conserved protein domains -- called macrodomains -- that are found in several viruses that cause human disease, such as hepatitis E virus, rubella virus, all coronaviruses and all alphaviruses. (jhsph.edu)
- Our study measuring the mosquito's ability to pass along the disease contributes to our understanding of the epidemiology of chikungunya. (southeastagnet.com)
- Although Chikungunya may be relatively new to the United States, the mosquito that transmits the disease is not. (trulynolen.com)
- According to the researchers, this effect proved especially beneficial - as exposure to the HCV virus caused severe liver disease and was known to affect more than 160 million people around the world. (naturalnews.com)
Zika and Chikungunya Viruses1
- According to a team of researchers from the Pasteur Institute in France, the turmeric compound not only inhibited the growth of zika and chikungunya viruses, but also halted the ability of these harmful viruses to infect otherwise healthy cells. (naturalnews.com)
Case of Chikungunya virus1
- The Mississippi State Department of Health is investigating its first potential case of chikungunya virus, a mosquito-borne illness traditionally found in Africa and Asia. (cogwriter.com)
Test for chikungunya virus2
- Researchers from Japan and India have developed a rapid and effective test for chikungunya virus that will more suitable for use in developing countries than current diagnostic techniques. (scidev.net)
- No laboratories in New Zealand currently test for Chikungunya virus. (health.govt.nz)
Strain of chikungunya virus1
- The Indian Ocean strain of chikungunya virus caused an outbreak in the Indian Ocean region with an estimated 1.5 million human cases from 2004 to 2006, Alto said. (newswise.com)
Strains of chikungunya virus2
- A226V strains of Chikungunya virus, Reunion island, 2010. (thefreelibrary.com)
- S.v. A226V strains of Chikungunya virus, Reunion island, 2010. (thefreelibrary.com)
Fatal4
- The virus is not usually fatal, though, with 1 death in every 1,000 cases , and then usually only in the elderly or immune-compromised. (businessinsider.com)
- Chikungunya is spread by two mosquito species, and is typically not fatal. (foxnews.com)
- Chikungunya is generally not fatal, but the painful symptoms have led people to say "It won't kill you, but it may make you wish you were dead! (pestworld.org)
- The virus, which is transmitted by the Asian tiger mosquito, triggers flu-like symptoms that can last for months and in rare cases can be fatal. (uni-muenchen.de)
Illness3
- If you believe you have Chikungunya, prevent mosquito bites for the first week of your illness. (cor.net)
- State epidemiologist Anna Likos said in order for the virus to be transmitted from an infected person to an uninfected mosquito, they must be bitten within the first week of illness. (tbo.com)
- It can cause illness for 7 to 10 days, however, and those infected with chikungunya are more likely to develop symptoms. (ms.gov)
Spread20
- Chikungunya virus is spread to people by the bite of an infected mosquito. (cdc.gov)
- They spread the virus when they bite other people. (medlineplus.gov)
- Let your provider know if you have traveled recently in an area where the virus is spread. (medlineplus.gov)
- How does Chikungunya virus spread? (medicinenet.com)
- Sequence analysis of the viral genomes of imported and autochthonous isolates indicated new features for the potential emergence and spread of the virus in Europe. (nih.gov)
- Both dengue and the chikungunya virus are spread by the Aedes aegypti mosquito, and symptoms of both viruses appear similar, making detection of chikungunya more difficult. (businessinsider.com)
- So when you contract Chikungunya , the advice is to stay indoors on quarantine so that you don't spread it. (webpronews.com)
- This image shows magnified particles of the Chikungunya virus, which is spread by mosquitos. (livescience.com)
- If a person is infected and bitten by a mosquito, that mosquito may later spread the virus by biting another person. (cor.net)
- An infected mosquito can then spread the virus to other people. (cor.net)
- Vector control plays a key role in preventing the spread of Chikungunya virus. (medscape.com)
- Matthew Aliota, a scientist at the UW-Madison School of Veterinary Medicine (SVM) and first author of the paper -- published today (July 1, 2016) in the journal Scientific Reports -- says the bacteria could present a "novel biological control mechanism," aiding efforts to stop the spread of Zika virus. (eurekalert.org)
- There are not yet any approved Zika virus vaccines or antiviral medications, and ongoing mosquito control strategies have not been adequate to contain the spread of the virus. (eurekalert.org)
- It is a re-emerging virus that has a risk to spread globally, given the expanding dissemination of its mosquito vectors. (plos.org)
- Once again, human travel may have contributed to the rapid spread of the virus between islands because imported and autochthonous cases on Reunion Island occurred after a holiday period for residents on Reunion Island who often traveled to Madagascar. (thefreelibrary.com)
- The findings reinforce the need for officials to be on the lookout for dengue and chikungunya cases, and to find ways to control its spread in India. (medindia.net)
- It's not the first Georgia case of chikungunya, which is spread through mosquito bites. (cogwriter.com)
- Health officials in the Dominican Republic say a mosquito-borne virus has spread widely since making its first appearance in the country. (medicalxpress.com)
- Originating from the tropical range, the Chikungunya virus has spread increasingly to the north in recent years, and already reached the southern United States. (uni-muenchen.de)
- Chikungunya Virus Continues to Spread Throughout the U.S. (travelagentcentral.com)
India2
- Strains of this virus found in islands off Africa, states in India such as Kerala, Sri Lanka and in countries in South-East Asia had a mutation that allowed it to be passed on by the A. albopictus mosquito as well. (thehindu.com)
- A decade ago, the virus caused a major outbreak in the islands of the Indian Ocean, then reached India and Southeast Asia. (archives-ouvertes.fr)
Diseases9
- Phylogenetic analysis identified 28 Asian genotype vi- and Reemerging Infectious Diseases, Muntinlupa City ruses and 3 ECSA genotype viruses (Figure 1). (cdc.gov)
- Chikungunya has been on the U.S. public health radar for some time," said Dr. Lyle Petersen, director of the CDC's Division of Vector-Borne Diseases. (longislandpress.com)
- Diagnosis of Chikungunya will first and foremost be by exclusion of other diseases such as dengue and measles, based on symptoms and travel history. (health.govt.nz)
- We also examined antibodies to dengue viruses in the same sample (6) to increase our understanding of the epidemiologic features of both diseases. (thefreelibrary.com)
- We expect to see West Nile virus cases each year because it is established in Maryland, but we are also looking for imported mosquito-borne diseases in Maryland residents,' Dr. Katherine Feldman, Maryland public health veterinarian, said in a statement. (baltimoresun.com)
- Diseases caused by these viruses are of great public health relevance, however, their epidemiological features in areas where the three viruses co-circulate are scarce. (unboundmedicine.com)
- Your doctor may order blood tests to look for Chikungunya or other similar diseases. (pestworld.org)
- This Protocol allows BCW's mobile team to collect samples globally for Chikungunya and other emerging infectious diseases. (infectioncontroltoday.com)
- The findings, published Jan. 30 in the Proceedings of the National Academy of Sciences, could be a first step toward developing drugs to treat or prevent diseases caused by alphaviruses (such as chikungunya) and coronaviruses (such as SARS). (jhsph.edu)
Dengue virus2
- Zika virus belongs to the same family as dengue virus and Aliota and Osorio -- with co-authors Stephen Penaido at SVM and Ivan Dario Velez, at the Universidad de Antioquia in Medellin, Colombia -- asked whether Wolbachia -harboring Aedes aegypti may also be effective against Zika virus. (eurekalert.org)
- A new study reveals how dengue virus manages to reproduce itself in an infected person without triggering the body's normal defenses. (medicalxpress.com)
Officials11
- Officials are sounding the alarm about the growing national threat of another mosquito-borne tropical virus known as Chikungunya, which recently infected three Long Islanders, who contracted it while traveling abroad. (longislandpress.com)
- WEST PALM BEACH - Health officials say that for the first time, an American has been infected with chikungunya by a mosquito here in the United States. (tbo.com)
- That's why health officials believe the virus is spreading here: The two cases had not recently left the country. (tbo.com)
- US health officials are on high alert as a mosquito-borne virus that yet has no cure has struck six of the US states. (rt.com)
- The latest case of the virus has been confirmed by Tennessee officials as the resident of Madison County, has been tested positive for the virus. (rt.com)
- State health officials said this week they have begun annual monitoring for West Nile and also for chikungunya, urging residents to avoid mosquito bites by using repellent, wearing long sleeves and pants when concerned about mosquito exposure, and clearing yards and other outside areas of potential mosquito breeding grounds. (baltimoresun.com)
- Costa Rican Health Ministry officials on Thursday confirmed two more cases of the chikungunya virus. (ticotimes.net)
- Last month, officials issued a preventive alert prompted by a report of 300 confirmed cases of chikungunya in that country. (ticotimes.net)
- The chikungunya virus won't likely kill you, but you won't forget having it, either, say health officials. (revolutionradio.org)
- The macrodomain in the chikungunya virus is similar in all alphaviruses, which encompass several viruses that have no cure or treatment such as Venezuelan equine encephalitis virus (which U.S. officials consider a potential bioterrorist threat) and the Mayaro virus, which some scientists have called the "next Zika. (jhsph.edu)
- According to the 7online.com report, health officials said the virus is not contagious from person to person, is typically not life threatening and will likely resolve on its own. (travelagentcentral.com)
Prevalent3
- Where is Chikungunya virus most prevalent? (medicinenet.com)
- other cases had been reported in people who had recently traveled to areas where the virus is prevalent. (baltimoresun.com)
- However, one of the mosquito species that carries the virus is prevalent in Brazil. (cogwriter.com)
Vaccines4
- There are currently no vaccines for chikungunya, but findings from a small study published today (Aug. 15) have shown promise that one could be developed. (livescience.com)
- A broad range of vaccine strategies have been proposed and described, including inactivated virus formulations, live-attenuated virus, chimeric virus vaccines, DNA vaccines, adenoviral vectored vaccines, subunit protein vaccines and virus-like particle (VLP) formulations. (wur.nl)
- Now we need to use this information to help us find drugs or develop vaccines to stop the virus. (jhsph.edu)
- Vaccines in preclinical research stages include a chikungunya vaccine, a low-cost human papilloma virus vaccine, vaccines to protect against new forms of influenza, a vaccine to protect against West Nile and a combination plague/smallpox vaccine for biodefense. (fiercebiotech.com)
Presence of chikungunya2
- But blood samples sent for testing in France confirmed the presence of chikungunya . (newscientist.com)
- They did this by testing mosquito saliva for the presence of chikungunya virus. (southeastagnet.com)
Aedes aegypti and aedes albopictus1
- The mosquitos that carry the Chikungunya virus (aedes aegypti and aedes albopictus) can bite during the day and at night, both indoors and outdoors, and often live around buildings in urban areas. (pestworld.org)
Severe joint pain2
Albopictus6
- A team of scientists led by Scott C. Weaver of the University of Texas Medical Branch at Galveston in the U.S. has identified more E2 mutations, each of which, along with the change in the E1 protein, made the virus more efficient in establishing itself in A. albopictus . (thehindu.com)
- A lab-created virus with both the E2-L210Q and E2-K252Q mutations was far more effective than either one of those mutations at colonising A. albopictus . (thehindu.com)
- Both viruses are arthropod-borne viruses (arboviruses) sharing a common vector: mosquitos of the Aedes genus, specifically A. aegypti and A. albopictus [ 4 ]. (hindawi.com)
- People can get sick from chikungunya after an infected mosquito of the species Aedes aegypti, seen here, or Aedes albopictus bites them. (newswise.com)
- To further complicate matters, not only is Aedes albopictus now a good host for chikungunya virus, but the mosquito is spreading across the globe from eastern Asia to Europe and the United States. (virology.ws)
- albopictus vector competence for chikungunya virus through an adaptive co-evolution process. (pasteur.fr)