The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
An abnormal pattern of breathing characterized by alternating periods of apnea and deep, rapid breathing. The cycle begins with slow, shallow breaths that gradually increase in depth and rate and is then followed by a period of apnea. The period of apnea can last 5 to 30 seconds, then the cycle repeats every 45 seconds to 3 minutes.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
Mitochondria in hepatocytes. As in all mitochondria, there are an outer membrane and an inner membrane, together creating two separate mitochondrial compartments: the internal matrix space and a much narrower intermembrane space. In the liver mitochondrion, an estimated 67% of the total mitochondrial proteins is located in the matrix. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p343-4)
Centrifugation, Density Gradient
Electron Transport Complex IV
A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane.
Electrophoresis, Polyacrylamide Gel
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
Hemeproteins whose characteristic mode of action involves transfer of reducing equivalents which are associated with a reversible change in oxidation state of the prosthetic group. Formally, this redox change involves a single-electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom (From Enzyme Nomenclature, 1992, p539). The various cytochrome subclasses are organized by the type of HEME and by the wavelength range of their reduced alpha-absorption bands.
The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)
An electrochemical technique for measuring the current that flows in solution as a function of an applied voltage. The observed polarographic wave, resulting from the electrochemical response, depends on the way voltage is applied (linear sweep or differential pulse) and the type of electrode used. Usually a mercury drop electrode is used.
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide using energy obtained from light rather than from the oxidation of chemical compounds. Photosynthesis comprises two separate processes: the light reactions and the dark reactions. In higher plants; GREEN ALGAE; and CYANOBACTERIA; NADPH and ATP formed by the light reactions drive the dark reactions which result in the fixation of carbon dioxide. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone
Electron Transport Chain Complex Proteins
A complex of enzymes and PROTON PUMPS located on the inner membrane of the MITOCHONDRIA and in bacterial membranes. The protein complex provides energy in the form of an electrochemical gradient, which may be used by either MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES or BACTERIAL PROTON-TRANSLOCATING ATPASES.
Electron Transport Complex I
A flavoprotein and iron sulfur-containing oxidoreductase complex that catalyzes the conversion of UBIQUINONE to ubiquinol. In MITOCHONDRIA the complex also couples its reaction to the transport of PROTONS across the internal mitochondrial membrane. The NADH DEHYDROGENASE component of the complex can be isolated and is listed as EC 126.96.36.199.
Chromatography, Ion Exchange
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Techniques used to separate mixtures of substances based on differences in the relative affinities of the substances for mobile and stationary phases. A mobile phase (fluid or gas) passes through a column containing a stationary phase of porous solid or liquid coated on a solid support. Usage is both analytical for small amounts and preparative for bulk amounts.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Rats, Inbred Strains
Respiratory Physiological Phenomena
Respiratory Physiological Processes
Reactive Oxygen Species
Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.
Membrane Potential, Mitochondrial
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Carbonyl Cyanide m-Chlorophenyl Hydrazone
Amino Acid Sequence
Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.
Citric Acid Cycle
A flavoprotein and iron sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. In eukaryotes the enzyme can be found as a component of mitochondrial electron transport complex I. Under experimental conditions the enzyme can use CYTOCHROME C GROUP as the reducing cofactor. The enzyme was formerly listed as EC 188.8.131.52.
Electron Transport Complex II
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.
Cytochrome c Group
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
Mitochondrial ADP, ATP Translocases
A class of nucleotide translocases found abundantly in mitochondria that function as integral components of the inner mitochondrial membrane. They facilitate the exchange of ADP and ATP between the cytosol and the mitochondria, thereby linking the subcellular compartments of ATP production to those of ATP utilization.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Chromatography, High Pressure Liquid
Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Electron Transport Complex III
A multisubunit enzyme complex that contains CYTOCHROME B GROUP; CYTOCHROME C1; and iron-sulfur centers. It catalyzes the oxidation of ubiquinol to UBIQUINONE, and transfers the electrons to CYTOCHROME C. In MITOCHONDRIA the redox reaction is coupled to the transport of PROTONS across the inner mitochondrial membrane.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
Anion Exchange Protein 1, Erythrocyte
A major integral transmembrane protein of the ERYTHROCYTE MEMBRANE. It is the anion exchanger responsible for electroneutral transporting in CHLORIDE IONS in exchange of BICARBONATE IONS allowing CO2 uptake and transport from tissues to lungs by the red blood cells. Genetic mutations that result in a loss of the protein function have been associated with type 4 HEREDITARY SPHEROCYTOSIS.
A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)
The two lipoprotein layers in the MITOCHONDRION. The outer membrane encloses the entire mitochondrion and contains channels with TRANSPORT PROTEINS to move molecules and ions in and out of the organelle. The inner membrane folds into cristae and contains many ENZYMES important to cell METABOLISM and energy production (MITOCHONDRIAL ATP SYNTHASE).
Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).
Gene Expression Regulation, Bacterial
A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
Body Temperature Regulation
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma. EC 184.108.40.206.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Prognostic value of nocturnal Cheyne-Stokes respiration in chronic heart failure. (1/97)BACKGROUND: Nocturnal Cheyne-Stokes respiration (CSR) occurs frequently in patients with chronic heart failure (CHF), and it may be associated with sympathetic activation. The aim of the present study was to evaluate whether CSR could affect prognosis in patients with CHF. METHODS AND RESULTS: Sixty-two CHF patients with left ventricular ejection fraction /=30/h and left atria >/=25 cm2. CONCLUSIONS: The AHI is a powerful independent predictor of poor prognosis in clinically stable patients with CHF. The presence of an AHI >/=30/h adds prognostic information compared with other clinical, echocardiographic, and autonomic data and identifies patients at very high risk for subsequent cardiac death. (+info)
High prevalence and persistence of sleep apnoea in patients referred for acute left ventricular failure and medically treated over 2 months. (2/97)AIMS: Cardiac failure patients were studied systematically using polysomnography 1 month after recovering from acute pulmonary oedema, and again after 2 months of optimal medical treatment for cardiac failure. METHODS AND RESULTS: This prospective study of consecutive patients was conducted in a cardiac care unit of a university hospital. V o(2)measurements and left ventricular ejection fraction were recorded. Thirty-four patients, initially recruited with pulmonary oedema, improved after 1 month of medical treatment to NYHA II or III. They were aged less than 75 years and had a left ventricular ejection fraction less than 45% at the time of inclusion. Age was 62 (9) years, body mass index= 27 (5) kg x m(-2)and an ejection fraction= 30 (10)%. Eighteen of the 34 patients (53%) had coronary artery disease. Twenty-eight of the 34 had sleep apnoea syndrome with an apnoea+hypopnoea index >15 x h(-1)of sleep. Thus, the prevalence of sleep apnoea in this population was 82%. Twenty-one of 28 (75%) patients had central sleep apnoea and seven of 28 (25%) had obstructive sleep apnoea. Patients with central sleep apnoea had a lower Pa co(2)than those with obstructive sleep apnoea (33 (5) vs 37 (5) mmHg, P<0.005). Significant correlations were found between apnoea+hypopnoea index and peak exercise oxygen consumption (r= -0.73, P<0.01), and apnoea+hypopnoea index and Pa co(2)(r= -0.42, P = 0.03). When only central sleep apnoea patients were considered, a correlation between apnoea+hypopnoea index and left ventricular ejection fraction was also demonstrated (r= -0.46, P<0.04). After 2 months of optimal medical treatment only two patients (both with central sleep apnoea) showed improvement (apnoea+hypopnoea index <15 x h(-1)). CONCLUSIONS: We have demonstrated a high prevalence of sleep apnoea, which persisted after 2 months of medical treatment, in patients referred for acute left ventricular failure. Central sleep apnoea can be considered a marker of the severity of congestive heart failure. (+info)
Second by second patterns in cortical electroencephalograph and systolic blood pressure during Cheyne-Stokes. (3/97)Little is known about how arousal develops during the ventilatory phase of Cheyne-Stokes breathing. This study employs neural network analysis of electroencephalograms (EEGs) to describe these changes and relate them to changes in systolic blood pressure, which is probably a subcortical marker of arousal. Six patients with Cheyne-Stokes respiration (apnoea/hypopnoea index 32-69 h(-1)) caused by stable chronic heart failure underwent polysomnography including arterial beat-to-beat systolic blood pressure determination. Periods of 15 sequential apnoeas during nonrapid eye movement sleep were identified for each subject. For each apnoea, the EEG was examined second-by-second using neural net analysis from 28 s before to 28 s after apnoea termination (first return of oronasal airflow), and this was compared with the systolic blood pressure pattern. During the apnoeic phase, sleep deepened progressively. Arousal started to develop at or just before apnoea termination and progresses through the breathing phase. The rise and fall in the systolic blood pressure closely followed the rise and fall in electroencephalographic sleep depth. In conclusion, during Cheyne-Stokes breathing, cortical electroencephalographic arousal begins at or just before the resumption of breathing. Cortical electroencephalographic sleep depth changes are closely mirrored by changes in arterial systolic blood pressure, suggesting that the state changes in the cortical and basal brain structures may be synchronous. (+info)
Oscillatory breathing patterns during wakefulness in patients with chronic heart failure: clinical implications and role of augmented peripheral chemosensitivity. (4/97)BACKGROUND: Oscillatory breathing patterns characterized by rises and falls in ventilation with apnea (Cheyne-Stokes respiration [CSR]) or without apnea (periodic breathing [PB]) commonly occur during the daytime in chronic heart failure (CHF). We have prospectively characterized patients with cyclical breathing in terms of clinical characteristics, indices of autonomic control, prognosis, and the role of peripheral chemosensitivity. METHODS AND RESULTS: To determine cyclical breathing pattern, power spectral analysis was applied to 30-minute recordings of respiration in 74 stable CHF patients. Analyses of heart rate variability and baroreflex sensitivity were used to assess autonomic balance. Peripheral chemosensitivity was assessed with the transient hypoxia method. We also determined whether the suppression of peripheral chemoreceptor activity (hyperoxia or dihydrocodeine) would influence the respiratory pattern. Cyclical respiration was found in 49 (66%) patients (22 [30%] CSR, 27 [36%] PB) and was associated with more advanced CHF symptoms, impaired autonomic balance, and increased chemosensitivity (0.80 and 0.75 versus 0.34 L. min(-1). %SaO(2)(-1), P<0.001, for CSR and PB versus normal breathing, respectively). Transient hyperoxia abolished oscillatory breathing in 7 of 8 patients. Dihydrocodeine administration decreased chemosensitivity by 42% (P=0.05), which correlated with improvement in respiratory pattern. Cyclical breathing predicted poor 2-year survival (relative risk 9.41, P<0.01, by Cox proportional hazards analysis), independent of peak oxygen consumption (P=0.04). CONCLUSIONS: An oscillatory breathing pattern during the daytime is a marker of impaired autonomic regulation and poor outcome. Augmented activity of peripheral chemoreceptors may be involved in the genesis of this respiratory pattern. Modulation of peripheral chemosensitivity can reduce or abolish abnormal respiratory patterns and may be an option in the management of CHF patients with oscillatory breathing. (+info)
Effects of continuous positive airway pressure on cardiovascular outcomes in heart failure patients with and without Cheyne-Stokes respiration. (5/97)BACKGROUND: Continuous positive airway pressure (CPAP) improves cardiac function in patients with congestive heart failure (CHF) who also have Cheyne-Stokes respiration and central sleep apnea (CSR-CSA). However, the effects of CPAP in CHF patients without CSR-CSA have not been tested, and the long-term effects of this treatment on clinical cardiovascular outcomes are unknown. METHODS AND RESULTS: We conducted a randomized, controlled trial in which 66 patients with CHF (29 with and 37 without CSR-CSA) were randomized to either a group that received CPAP nightly or to a control group. Change in left ventricular ejection fraction (LVEF) from baseline to 3 months and the combined mortality-cardiac transplantation rate over the median 2.2-year follow-up period were compared between the CPAP-treated and control groups. For the entire group of patients, CPAP had no significant effect on LVEF, but it was associated with a 60% relative risk reduction (95% confidence interval, 2% to 64%) in mortality-cardiac transplantation rate in patients who complied with CPAP therapy. Stratified analysis of patients with and without CSR-CSA revealed that those with CSR-CSA experienced both a significant improvement in LVEF at 3 months and a relative risk reduction of 81% (95% confidence interval, 26% to 95%) in the mortality-cardiac transplantation rate of those who used CPAP. CPAP had no significant effect on either of these outcomes in patients without CSR-CSA. CONCLUSIONS: CPAP improves cardiac function in CHF patients with CSR-CSA but not in those without it. Although not definitive, our findings also suggest that CPAP can reduce the combined mortality-cardiac transplantation rate in those CHF patients with CSR-CSA who comply with therapy. (+info)
Quantitative general theory for periodic breathing in chronic heart failure and its clinical implications. (6/97)BACKGROUND: In patients with chronic heart failure (CHF), periodic breathing (PB) predicts poor prognosis. Clinical studies have identified numerous risk factors for PB (which also includes Cheyne-Stokes respiration). Computer simulations have shown that oscillations can arise from delayed negative feedback. However, no simple general theory quantitatively explains PB and its mechanisms of treatment using widely-understood clinical concepts. Therefore, we introduce a new approach to the quantitative analysis of the dynamic physiology governing cardiorespiratory stability in CHF. METHODS AND RESULTS: An algebraic formula was derived (presented as a simple 2D plot), enabling prediction from easily acquired clinical data to determine whether respiration will be unstable. Clinical validation was performed in 20 patients with CHF (10 with PB and 10 without) and 10 healthy normal subjects. Measurements, including chemoreflex sensitivity (S) and delay (delta), alveolar volume (V(L)), and end-tidal CO(2) fraction (C), were applied to the stability formula. The breathing pattern was correctly predicted in 28 of the 30 subjects. The principal combined parameter (CS)x(delta/V(L)) was higher in patients with PB (14.2+/-3.0) than in those without PB (3.1+/-0.5; P:=0.0005) or in normal controls (2.4+/-0.5; P:=0.0003). This was because of differences in both chemoreflex sensitivity (1749+/-235 versus 620+/-103 and 526+/-104 L/min per atm CO(2); P:=0.0001 and P:<0.0001, respectively) and chemoreflex delay (0.53+/-0.06 vs 0.40+/-0.06 and 0.30+/-0.04 min; P:=NS and P:=0.02). CONCLUSION: This analytical approach identifies the physiological abnormalities that are important in the genesis of PB and explicitly defines the region of predicted instability. The clinical data identify chemoreflex gain and delay time (rather than hyperventilation or hypocapnia) as causes of PB. (+info)
Cognitive impairment in heart failure with Cheyne-Stokes respiration. (7/97)OBJECTIVES: To document the degree of cognitive impairment in stable heart failure, and to determine its relation to the presence of Cheyne-Stokes respiration during sleep. SUBJECTS: 104 heart failure patients and 21 healthy normal volunteers. METHODS: Overnight oximetry was used (previously validated as a screening tool for Cheyne-Stokes respiration in heart failure). Cognitive function was assessed using a battery of neuropsychological tests. Left ventricular function was assessed by echocardiography. RESULTS: Heart failure patients performed worse than the healthy volunteers in tests that measured vigilance. Reaction times were 48% slower (0.89 (0.03) s v 0.60 (0.05) s p < 0.005) and they hit twice as many obstacles on the Steer Clear simulator (75 (6.4) v 33 (4.6); p < 0.005). Cognitive impairment within the heart failure group was unrelated to either the presence of Cheyne-Stokes respiration, the degree of left ventricular dysfunction, or indices of nocturnal oxygenation. CONCLUSIONS: Vigilance was impaired in heart failure but this did not appear to be related to the presence of Cheyne-Stokes respiration during sleep. Impaired vigilance as measured on the Steer Clear test has been associated with an increased risk of motor vehicle accidents. The issue of fitness to drive in heart failure requires further attention. (+info)
Characterisation of breathing and associated central autonomic dysfunction in the Rett disorder. (8/97)AIM: To investigate breathing rhythm and brain stem autonomic control in patients with Rett disorder. SETTING: Two university teaching hospitals in the United Kingdom and the Rett Centre, Sweden. PATIENTS: 56 female patients with Rett disorder, aged 2-35 years; 11 controls aged 5-28 years. DESIGN: One hour recordings of breathing movement, blood pressure, ECG R-R interval, heart rate, transcutaneous blood gases, cardiac vagal tone, and cardiac sensitivity to baroreflex measured on-line with synchronous EEG and video. Breathing rhythms were analysed in 47 cases. RESULTS: Respiratory rhythm was normal during sleep and abnormal in the waking state. Forced and apneustic breathing were prominent among 5-10 year olds, and Valsalva breathing in the over 18 year olds, who were also most likely to breathe normally. Inadequate breathing peaked among 10-18 year olds. Inadequate and exaggerated breathing was associated with vacant spells. Resting cardiac vagal tone and cardiac sensitivity to baroreflex were reduced. CONCLUSIONS: Labile respiratory rhythms and poor integrative inhibition in Rett disorder suggest brain immaturity. Linking this to an early monoaminergic defect suggests possible targets for the MECP2 gene in clinical intervention. Exaggerated and inadequate autonomic responses may contribute to sudden death. (+info)
Cheyne-Stokes respiration - How is Cheyne-Stokes respiration abbreviated?
CSR - Cheyne-Stokes respiration. Looking for abbreviations of CSR? It is Cheyne-Stokes respiration. Cheyne-Stokes respiration listed as CSR
Cheyne-Stokes respiration - Wikipedia
Cheyne-Stokes respiration /ˈtʃeɪnˈstoʊks/ is an abnormal pattern of breathing characterized by progressively deeper, and sometimes faster, breathing followed by a gradual decrease that results in a temporary stop in breathing called an apnea. The pattern repeats, with each cycle usually taking 30 seconds to 2 minutes. It is an oscillation of ventilation between apnea and hyperpnea with a crescendo-diminuendo pattern, and is associated with changing serum partial pressures of oxygen and carbon dioxide. Cheyne-Stokes respiration and periodic breathing are the two regions on a spectrum of severity of oscillatory tidal volume. The distinction lies in what is observed at the trough of ventilation: Cheyne-Stokes respiration involves apnea (since apnea is a prominent feature in their original description) while periodic breathing involves hypopnea (abnormally small but not absent breaths). These phenomena can occur during wakefulness or during sleep, where they are called the central sleep apnea ...
Cardiac resynchronization therapy improves central sleep apnea and Cheyne-Stokes respiration in patients with chronic heart...
In HF patients, increased LV filling pressures can lead to pulmonary congestion and activation of pulmonary vagal irritant receptors, provoking hyperventilation and hypocapnia. Central sleep apnea occurs when arterial carbon dioxide partial pressures fall below the apneic threshold. The cycle length of alternating periods of hypocapnia-induced apnea and reflex hyperventilation (i.e., Cheyne-Stokes respiration ) is inversely proportional to cardiac output (12)and thus directly related to the severity of HF. A reduced LV function delays the circulation time between the lungs and the chemoreceptors (13)and increases the sensitivity of chemoreceptors, especially to carbon dioxide (14). The degree of carbon dioxide hypersensitivity is a major determinant of Cheyne-Stokes respiration (15). An increase in chemoreflex sensitivity is mirrored by an elevated ventilatory response to exercise in HF patients (16).. Our study is the first to show that CRT improves cardiac function and reduces the severity ...
Cheyne-Stokes respiration is not related to quality of life or sleepiness in heart failure
Background and aims: The effects of central sleep apnea in Cheyne-Stokes respiration on sleep-related symptoms and quality of life are not very well established. We aimed to investigate whether Cheyne-Stokes respiration is related to health-related quality of life. We also studied the impact on daytime sleepiness and nocturnal dyspnea.. Methods: Included were 203 consecutive patients, stabilized following in-hospital treatment for decompensated congestive heart failure. They underwent overnight cardiorespiratory sleep apnea recordings in hospital and answered a set of questions on symptoms and health-related quality of life questionnaires in the form of the Nottingham Health Profile and the Minnesota Living with Heart Failure Questionnaire. After excluding seven patients with predominantly obstructive apneas and 14 with insufficient recordings, 182 patients were included in the final analysis.. Results: One third of the patients had an apnea-hypopnea index (AHI) of ,30. Falling asleep in front ...
Continuous Positive Airway Pressure in Patients With Congestive Heart Failure and Cheyne-Stokes Respiration With Central Sleep...
Mehta and Groth raise several important points about our study. Because there was only a single reassessment of left ventricular ejection fraction (LVEF) 3 months into the trial, we could not evaluate whether improvements in LVEF were sustained beyond this period. However, we are presently conducting a long-term, multicenter, randomized trial of continuous positive airway pressure (CPAP) in patients with congestive heart failure (CHF) and Cheyne-Stokes respiration with central sleep apnea (CSR-CSA), the Canadian Positive Airway Pressure for Heart Failure (CANPAP) trial, with cardiac transplant-free survival as the primary outcome.R1 Serial measurements of LVEF will be made throughout the 5-year duration of the trial. This will allow us to determine whether early improvements in LVEF are sustained and related to the primary outcome.. Although we did not measure the effects of CPAP on the severity of CSR-CSA in our latest trial, we have done so previously. Naughton et alR2 demonstrated a 65% ...
Cognitive impairment in heart failure with Cheyne-Stokes respiration | Heart
We reasoned that Cheyne-Stokes respiration during sleep might lead to cognitive dysfunction as a result of either apnoea related cerebral hypoxia or increased sleep fragmentation. This hypothesis was based upon the observations from earlier studies in healthy volunteers and patients with obstructive sleep apnoea. Hypoxia has been shown to impair cognitive function in normal subjects at altitude1and in chronic obstructive pulmonary disease.13 Sleep fragmentation has been shown to increase subjective and objective measurements of daytime sleepiness2 14 and cognitive dysfunction2 in normal healthy volunteers.. Obstructive sleep apnoea is associated with cognitive impairment that is reversed by continuous positive airways pressure.15 The origin of this impairment is unclear. Findlay reported that nocturnal hypoxia alone predicted impaired cognitive function.16 Other investigators report that both hypoxia and sleep fragmentation have a role in generating cognitive dysfunction. Bedard and colleagues ...
Cheyne-Stokes Respiration & Intracerebral Hematoma & Seizure: Causes & Reasons - Symptoma
Cheyne-Stokes Respiration & Intracerebral Hematoma & Seizure Symptom Checker: Possible causes include Stroke. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
Cheyne-Stokes respiration | Diagnosaurus
Cheyne-Stokes respiration answers are found in the Diagnosaurus powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
Central Sleep Apnea Syndrome (Idiopathic CSA, Cheyne-Stokes Respiration, CSA due to a drug or substance, High-altitude Periodic...
Cancer Therapy Advisor provides pulmonary medicine specialists with the latest information to correctly diagnose the latest pulmonary medical conditions, recommend procedures and guides. Visit often for updates and new information.
breathing treatment for congestive heart failure
Registered Charity Number 1151848. Systolic congestive heart failure makes it difficult for the heart to pump blood through the body, meaning that other organs get less blood than they need. NLM Congestive heart failure (CHF) is a chronic heart condition that affects how the heart pumps blood. There are a lot of interesting things you can do with breathing, said Dr. Uber, Physicians can teach patients how to synchronize their breath properly and this requires little practice for 15 minutes a day. Copyright © 2014 Elsevier Inc. All rights reserved. Effect of cardiac resynchronization therapy on sleep quality, quality of life, and symptomatic depression in patients with chronic heart failure and Cheyne-Stokes respiration. Your vet may prescribe additional diuretics like furosemide. BPAP; CPAP; Central sleep apnea; Cheyne-Stokes respiration; Heart failure; Obstructive sleep apnea; Sleep apnea; Sleep-disordered breathing. Pumping Marvellous Foundation, Suite 111 Business First, Millennium City ...
Adaptive servoventilation improves cardiac function and respiratory stability.
Cheyne-Stokes respiration (CSR) in patients with chronic heart failure (CHF) is of major prognostic impact and expresses respiratory instability. Other parameters are daytime pCO₂, VE/VCO₂-slope during exercise, exertional oscillatory ventilation
CHEYNE-STOKES | Apnea Board
How serious is cheyne-stokes respiration and when is it important to seek medical attention? My device has indicated 1 episode on May 4, 2016 2 episodes on July 5, 2016 [AHI 11.93 CSR 15.06% 10:04:06
Publications - Institute for Bioengineering of Catalonia (IBEC)
Assessment of the dynamic interactions between cardiovascular signals can provide valuable information that improves the understanding of cardiovascular control. Heart rate variability (HRV) analysis is known to provide information about the autonomic heart rate modulation mechanism. Using the HRV signal, we aimed to obtain parameters for classifying patients with and without chronic heart failure (CHF), and with periodic breathing (PB), non-periodic breathing (nPB), and Cheyne-Stokes respiration (CSR) patterns. An electrocardiogram (ECG) and a respiratory flow signal were recorded in 36 elderly patients: 18 patients with CHF and 18 patients without CHF. According to the clinical criteria, the patients were classified into the follow groups: 19 patients with nPB pattern, 7 with PB pattern, 4 with Cheyne-Stokes respiration (CSR), and 6 non-classified patients (problems with respiratory signal). From the HRV signal, parameters in the time and frequency domain were calculated. Frequency domain ...
Adaptive servoventiation therapy (ASV) is designed to treat hypocapnic central sleep apnoea (Cheyne-Stokes respiration) in heart failure (HF) . It remains unclear whether this therapy increases stroke volume (SV) and if, this is mediated by a decrease in cardiac afterload due to increased parasympathetic nervous activity (PNA) or by a change in baroreceptor reflex sensitivity.. 12 patients with HF (12 male; 70 ± 9 years; NYHA ≥ II; EF ≤ 45% and Cheyne- Stokes respiration) and 14 healthy volunteers (13 male, 24 ± 4 years, EF ≥ 60%, AHI , 5/h) were ventilated non-invasively for 1 h with ASV (PaceWave™). Hemodynamic effects were analyzed non-invasively and compared to findings 30 min before and after ASV.. Changes in SV on ASV were significantly different between both groups (+5 ± 8% in HF patients vs. -4 ± 9% in volunteers, p=0.01). HF demonstrated a significant increase in markers of PNA (HFnuRRI) during ASV (56 ± 21 % vs. 68 ± 20 % on ASV; p=0.02), whereas volunteers showed a shift ...
JCSM - Detection of Sleep Disordered Breathing and Its Central/Obstructive Character Using Nasal Cannula and Finger Pulse...
The current study demonstrated for the first time that a novel computer algorithm based on a combination of nasal air flow and photoplethysmographic pulse wave signals may be used to accurately detect and differentiate obstructive and central sleep apnea events. In addition, an algorithm based on the pulse oximeter signal alone provided a good quantitative estimate of SDB severity.. OSA, the most common type of SDB, has been associated with cardiovascular, metabolic, and pulmonary comorbidities.20 In the light of a growing need for diagnosis and treatment of SDB patients, unattended home sleep studies using portable monitoring devices have been widely applied in the clinical setting. For instance, ambulatory cardiorespiratory polygraphy have been used for CSA/Cheyne-Stokes respiration detection in heart failure patients.2,21 According to the AASM, a minimum of heart rate, oxygen saturation, and respiratory analysis (e.g., by airflow or peripheral arterial tone) is required for out-of-center ...
Sleep-Disordered Breathing and Cardiovascular Disease | Circulation
CSA is especially relevant to CHF. The prevalence of CSA in CHF patients is dependent on various factors, such as heart failure etiology, gender, age, ejection fraction, and hemodynamic status, and has been estimated at 40% to 60%.2,3 Cheyne-Stokes respiration occurs during CSA and is a distinct pattern of periodic breathing with alternating crescendo-decrescendo sequences of hyperventilation and apnea (ie, complete breathing cessation).. CSA may have an important influence on prognosis, in that its presence is associated with increased mortality in CHF patients.3 This effect appears to be independent of other known risk factors, such as left ventricular ejection fraction or peak oxygen consumption.. Although the association of CSA with CHF has been recognized for decades, it is unclear whether CSA directly affects CHF pathophysiology and can therefore be causally linked to prognosis, or whether it is rather an index of the severity of CHF. Evidence implicating CSA in CHF progression includes ...
Publications - Institute for Bioengineering of Catalonia (IBEC)
High altitude periodic breathing (PB) shares some common pathophysiologic aspects with sleep apnea, Cheyne-Stokes respiration and PB in heart failure patients. Methods that allow quantifying instabilities of respiratory control provide valuable insights in physiologic mechanisms and help to identify therapeutic targets. Under the hypothesis that high altitude PB appears even during physical activity and can be identified in comparison to visual analysis in conditions of low SNR, this study aims to identify PB by characterizing the respiratory pattern through the respiratory volume signal. A number of spectral parameters are extracted from the power spectral density (PSD) of the volume signal, derived from respiratory inductive plethysmography and evaluated through a linear discriminant analysis. A dataset of 34 healthy mountaineers ascending to Mt. Muztagh Ata, China (7,546 m) visually labeled as PB and non periodic breathing (nPB) is analyzed. All climbing periods within all the ascents are ...
Papers with the keyword etiology classification and epidemiology of stoke | Read by QxMD
We investigated the relationship between sleep-disordered breathing (SDB) and Cheyne-Stokes respiration (CSR) while awake as well as mortality. Eighty-nine consecutive outpatients (29 females) with congestive heart failure (CHF; left ventricular ejection fraction, LVEF ,45%) were prospectively evaluated. The presence of SDB and of CSR while awake before sleep onset was investigated by polysomnography. SDB prevalence was 81 and 56%, using apnea-hypopnea index cutoffs ,5 and ,15, respectively. CHF etiologies were similar according to the prevalence of SDB and sleep pattern ...
Respiration - Wikipedia
Cheyne-Stokes respiration, an abnormal pattern of breathing characterized by progressively deeper and sometimes faster breathing, followed by a gradual decrease that results in a temporary stop in breathing called an ...
Pulmonary Disorders | Current Medical Diagnosis & Treatment 2018 | AccessMedicine | McGraw-Hill Medical
The pattern of breathing refers to the respiratory rate and rhythm, the depth of breathing or tidal volume, and the relative amount of time spent in inspiration and expiration. Normal values are a rate of 12-14 breaths per minute, tidal volumes of 5 mL/kg, and a ratio of inspiratory to expiratory time of approximately 2:3. Tachypnea is an increased rate of breathing and is commonly associated with a decrease in tidal volume. Respiratory rhythm is normally regular, with a sigh (1.5-2 times normal tidal volume) every 90 breaths or so to prevent collapse of alveoli and atelectasis. Alterations in the rhythm of breathing include rapid, shallow breathing, seen in restrictive lung disease and as a precursor to respiratory failure; Kussmaul breathing, rapid large-volume breathing indicating intense stimulation of the respiratory center, seen in metabolic acidosis; and Cheyne-Stokes respiration, a rhythmic waxing and waning of both rate and tidal volumes that includes regular periods of apnea. This last ...
Dicodid - Analgesics, Antitussives, Narcotics, ATC:R05DA03
Symptoms of overdose include respiratory depression (a decrease in respiratory rate and/or tidal volume, Cheyne-Stokes respiration, cyanosis), extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, dizziness, ringing in the ears, confusion, blurred vision, eye problems, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdose, apnea, circulatory collapse, cardiac arrest and death may occur. LD50=85.7mg/kg (subcutaneous, in mice ...
beat kidney disease pdf
ViewerPreferences/Metadata 22 0 R/Pages 170 0 R/PageLayout/SinglePage/OpenAction 174 0 R/StructTreeRoot 42 0 R/Type/Catalog/Lang(EN-US)>> endobj 174 0 obj endobj 175 0 obj /Font/ProcSet[/PDF/Text]/ExtGState>>/Type/Page>> endobj 176 0 obj stream Your kidneys filter extra potassium into your urine. A distinctive pattern called Cheyne-Stokes respiration might be heard: a loud, deep inhalation is followed by a pause of not breathing Kidneys are the bodys natural filter. Best Kidney Disease Treatments and Diet - You are About to Discover What Your Doctor Got Wrong About Kidney Disease And This Article Will Help You to Learn How to Reverse Your Kidney Failure Naturally!!!!! Popular Topics. Do not wait until later to cure your kidneys. ❤. Your treatment is based on your stage of kidney disease. Kidney Disease Solution Duncan Capicchiano October 30, 2020. Meanwhile, signs of kidney disease begin to appear. Ask your doctor or start treatment using Duncan Capicchianos ebook. The kidneys ...
Blu-Phen - Hypnotics and Sedatives, Anticonvulsants
CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur ...
Sleep-induced ventilatory dysfunction in Downs syndrome.
Three patients with Downs syndrome demonstrated severe sleep-induced ventilatory failure characterized by Cheyne-Stokes respiration with superimposed obstruction of the upper airway. Anatomic otolaryngologic factors were present in two of the three
Professor Ronney B Panerai - University of Leicester
Publications. Hanby MF, Panerai RB, Robinson TG, Haunton VJ (2017) Is cerebral vasomotor reactivity impaired in Parkinson disease?. Clinical Autonomic Research, 27 (2), pp. 107-111 10.1007/s10286-017-0406-x. Caldas J, Panerai RB, Bor-Seng-Shu E, Almeida J, Ferreira G, Cunha L, Nogueira R, Oliveira M, Jatene F, Robinson T, Hajjar L (2017) Cerebral hemodynamic with intra-aortic balloon pump: business as usual?. Physiological measurement, 10.1088/1361-6579/aa68c4. Nogueira RC, Panerai RB, Teixeira MJ, Robinson TG, Bor-Seng-Shu E (2017) Cerebral Hemodynamic Effects of Cheyne-Stokes Respiration in a Patient with Stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 10.1016/j.jstrokecerebrovasdis.2017.02.026. Caldas JR, Panerai RB, Haunton VJ, Almeida JP, Ferreira GSR, Camara L, Nogueira RC, Bor-Seng-Shu E, Oliveira ML, Groehs RRV, Ferreira-Santos L, Teixeira MJ, Galas FRBG, Robinson TG, Jatene FB, Hajjar LA (2017) Cerebral blood flow ...
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To diagnose brain ful stimuli; cheyne-stokes respiration is gradually increased from 9:75 73. Food and drug hypersensitivity often present with nonseminomatous germ-cell tumors. Section). Fiorino, c., reni, m., bolognesi, a., et al: Positron emission tomography scan or mr angiography have been suggested between the urinary ciated with diminished involvement in systemic by aortic root diameter, a moderately addicted patient initially requiring 31 40 < 26 mg/day, 55 mcg buccally tive dose, every 11 hours as needed the product of negative cul- ability to frighten 3 moderate, with patient compli- intellectual deterioration (memory impairment, inability to see an apparently prolonged and the tempo- transient relaxations of the major change in kidney cancer. When sulfonylureas, repaglinide glucose output becomes totally dependent on the right colon pouches, an appendiceal continence mecha- example, in the diagnosis by staphylococci or enterococci and when a single 32. Spective. These complications are ...
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Mg iv or less at i took viagra any time, or dexamethasone. Unlike the cheyne-stokes breathing pattern seen in patients who have long-term adverse effects secondary to mechanical ventilation. Antibiotics may be tried for adenosine deaminase deficiency ada is an accompanying sign of anterior third of calf adapted from way lw ed, current surgical diagnosis & typical features painless, progressively enlarging mass embryonal botryoid variant in childhood and adolescence is roughly months, although some patients may be. Recommended parenteral acyclovir dosage for iv use give mg/kg over minutes, can cause oxygen consumption normally decreases by mg/ dl. General considerations factors that are less dense before menopause than those listed have been described. N engl j med. I. What does this head ct image suggest a. Sleep is a nice example of a presynaptic neuron and all must be considered. Identification of the viral infections can be used to treat iatrogenic hypothyroidism in of patients, age is the ...
AirSense 10 AutoSet for Her
Premium auto-adjusting sleep apnoea therapy device for women. New AutoSet for Her algorithm. Built-in wireless connectivity. Cheyne-Stokes & central apnoea detection. AutoRamp.
THE RESUSCITATION OF THE CENTRAL NERVOUS SYSTEM OF MAMMALS | JEM
The cerebral circulation was interrupted for periods of three to eighty-one minutes by ligation of the innominate and left subclavian arteries proximal to the origin of the vertebral, in ninety-three cats. Eleven dogs were used in the earlier experiments.. The eye reflexes disappear very quickly and a period of high blood pressure follows the occlusion immediately; vagus inhibition causes cardiac slowing and a fall in blood pressure, followed by a second rise after the vagus center succumbs to anaemia. Respiration stops temporarily (twenty to sixty seconds) after the beginning of occlusion, and then follows a series of strong gasps of the Cheyne-Stokes type, after which it stops until some time after the restoration of the cerebral circulation. The respiratory and vagus centers lose their power of functioning at approximately the same time. Asphyxial slowing of the heart may occur without the agency of the vagus center. The blood pressure slowly falls to a level which is maintained throughout ...
GeorginaField from United Kingdom - Whats On Sanya
Jewett waves brachial autonomic plexus expiration lateral aspect bacterial encephalitis chorioallantoic Cheyne-Stokes psychosis dofn extrinsic color inferior articular process lamina suprachoroidea choroidea kinetochore fibers CT scan Aerococcus lateral nasal process ...
Cheyne-Stokes psychosis | definition of Cheyne-Stokes psychosis by Medical dictionary
Looking for online definition of Cheyne-Stokes psychosis in the Medical Dictionary? Cheyne-Stokes psychosis explanation free. What is Cheyne-Stokes psychosis? Meaning of Cheyne-Stokes psychosis medical term. What does Cheyne-Stokes psychosis mean?
Safety Alert Issued for ASV (Adaptive Servoventilation) Treatment in Patients with Heart Failure and Central Sleep Apnea -...
Please note the hotline information at the bottom of this posting. It is a press release issued by RESMED regarding ASV. If you have any questions/concerns about your specific type of machine, please call the hotline. ResMed Provides Update on Phase IV SERVE-HF Study of Adaptive Servo-Ventilation (ASV) Therapy In Central Sleep Apnea and Chronic Heart Failure. Study Did Not Meet Primary Endpoint. Safety Signal of Increased Cardiovascular Mortality Found For ASV Therapy In People With Predominant Central Sleep Apnea and Symptomatic Chronic Heart Failure. Results and Safety Signal Observed Only In This Specific Study Population San Diego, Calif. - May 13, 2015 - ResMed (NYSE: RMD) today announced that SERVE-HF, a multinational, multicenter, randomized controlled Phase IV trial did not meet its primary endpoint. SERVE-HF was designed to assess whether the treatment of moderate to severe predominant central sleep apnea with Adaptive Servo-Ventilation (ASV) therapy could reduce mortality and morbidity ...
Biot respiration • LITFL Medical Blog • Medical Eponym Library
We stated in the previous pages that the various authors who wrote about Cheyne-Stokes respiration had mentioned it in tuberculous meningitis. We have observed the case of a 16‐year‐old young man. We collected several pneumographic graphs. These graphs are conspicuously different from those that we saw in fig I, especially in that before and after the pause there is no respiratory movement that gradually decrease and increase; but, a respiration that is deep, dyspnoeic, like a big sigh from the patient during those moments. On the other hand Trousseau, whose astute observation cannot be doubted, noted in his Clinique (part II, page 240), that periodic irregularity of breathing is a sign of tuberculous meningitis; but the reading of this paragraph shows that it is not Cheyne-Stokes. Without wanting to come to a definitive conclusion, it seems that in meningitis it is not really the true type of Cheyne-Stokes respiration, but close to this type and more regular. It is an issue that should be ...
Cheyne-Stokes respiration on display | Student Health Service
John Cheyne was born in Leith in 1777, the son of a general practitioner. Initially apprenticed by his father, he studied for an M.D. at the University of Edinburgh, graduating in 1805. Cheyne worked as an army surgeon, then at the Ordnance Hospital at Leith Fort. In 1809, he moved to practice in Dublin where he became the first Professor of Medicine at Royal College of Surgeons in Ireland in 1813. While there he published his description of a phenomenon of malfunctioning breathing in very sick patients. He noted that the patients breathing would stop entirely for a quarter of a minute then it would start again slowly, increase by degrees until it was heaving quickly then gradually cease again, with a total of approximately 30 breaths per minute. Some of the principle causes of this condition are brain haemorrhaging, advanced renal failure, heart failure and narcotic poisoning, therefore it is often thought of as a sign of imminent death ...
Central sleep apnea: Implications for congestive heart failure<...
TY - JOUR. T1 - Central sleep apnea. T2 - Implications for congestive heart failure. AU - Garcia-Touchard, Arturo. AU - Somers, Virend. AU - Olson, Lyle J.. AU - Caples, Sean M.. PY - 2008/6. Y1 - 2008/6. N2 - Congestive heart failure (HF), an exceedingly common and costly disease, is frequently seen in association with central sleep apnea (CSA), which often manifests as a periodic breathing rhythm referred to as Cheyne-Stokes respiration. CSA has historically been considered to be a marker of heart disease, since improvement in cardiac status is often associated with the attenuation of CSA. However, this mirroring of HF and CSA may suggest bidirectional importance to their relationship. In fact, observational data suggest that CSA, associated with repetitive oxyhemoglobin desaturations and surges in sympathetic neural activity, may be of pathophysiologic significance in HF outcomes. In light of the disappointing results from the first large trial assessing therapy with continuous positive ...
Sleep at Altitude | High Altitude Health
Change in Breathing Pattern. Many theories state that the periodic breathing pattern, common during sleep at high altitude, is a potential cause of sleep disturbances. Periodic breathing is a form of Cheyne-Stokes respiration and reflects changes in neural signaling due to hypoxia and alkalosis during sleep.4 Hypoxia is a respiratory stimulant while alkalosis is a respiratory depressant.4 This mixed signaling is the source of the altered breathing during non-REM sleep encountered at altitudes over 2500 m. The frequency of periodic breathing during sleep increases as the altitude increases.3,4,7. Decreased Sleep Efficiency Compared with sea level, several studies have depicted that sleep at higher altitude is characterized by decreased sleep efficiency, prolonged superficial stages of sleep, and reduced stages of deep sleep.12 The image below is a qualitative representation of sleep structure recorded at sea level and at high altitude. The area encircled by the outer line reflects the time in ...
Examination is a chapter in the book, Pulmonology, containing the following 36 pages: Croup Score, Diehr Rule to Diagnose Pneumonia, Pneumonia Severity Index, Respiratory Rate, Kussmaul Respiration, Pectus Carinatum, Pectus Excavatum, Pulmonary Embolism Pretest Probability, Coin Test, Succussion Splash, Hyperventilation, Tachypnea, Bradypnea, Dyspnea Index, BODE Index, Severe Community Acquired Pneumonia Criteria, Mortality Prediction Tool for Patients with Community Acquired Pneumonia, Pneumonia IRVS Prediction Tool, COPD Population Screener Questionnaire, Respiratory Distress in Children with Pneumonia, Lung Exam, Asthma Exacerbation Severity Evaluation, Pulmonary Embolism Severity Index, Pulmonary Embolism Rule-Out Criteria, Cheyne-Stokes Respiration, Lung Function Questionnaire, COPD Exacerbation Decision Tool, COPD Assessment Test, Asthma-Related Death Risk Factors, Hammans Sign, SOAR Pneumonia Score, Hestia Criteria, Clinical Severity Scoring System Tool, STOP-Bang Questionnaire, Multidrug
ResMed Provides Update on Phase III SERVE-HF Study of Adaptive Servo-Ventilation (ASV) Therapy In Central Sleep Apnea and...
- Study Did Not Meet Primary Endpoint - Safety Signal of Increased Cardiovascular Mortality Found For ASV Therapy In People With Predominant Central Sleep Apnea
Exercise end-tidal CO|inf|2|/inf| predicts central sleep apnea in patients with heart failure<...
TY - JOUR. T1 - Exercise end-tidal CO2 predicts central sleep apnea in patients with heart failure. AU - Cundrle, Ivan. AU - Somers, Virend. AU - Johnson, Bruce David. AU - Scott, Christopher G.. AU - Olson, Lyle J.. PY - 2015/6/1. Y1 - 2015/6/1. N2 - BACKGROUND: Increased CO2 chemosensitivity and augmented exercise ventilation are characteristic of patients with heart failure (HF) with central sleep apnea (CSA). The aim of this study was to test the hypothesis that decreased end-tidal CO2 by cardiopulmonary exercise testing predicts CSA in patients with HF. METHODS: Consecutive ambulatory patients with New York Heart Association II to III HF were prospectively evaluated by CO2 chemosensitivity by rebreathe, cardiopulmonary exercise testing, and polysomnography (PSG). Subjects were classified as having either CSA (n = 20) or no sleep apnea (n = 13) by PSG; a central apnea-hypopnea index (AHI) ≥ 5 was used to define CSA. Subgroups were compared by t test or Mann-Whitney test and data summarized ...
FDA approved implantable device for central sleep apnea | BioSky
Central sleep apnea is a disorder where your breathing repeatedly pauses during sleep because the brain doesnt send the proper signals to the diaphragm (these are the muscles that control your breathing).. The U.S. Food and Drug Administration (FDA) today approved a new treatment option for patients with moderate to severe central sleep apnea. Its an implantable device called The Remedé System developed by Respicardia Inc.. The device is surgically placed under the skin in the upper chest area. Thin wires are inserted into the blood vessels near the nerve thats responsible for sending signals to the diaphragm to stimulate breathing. The system monitors the patients respiratory signals during sleep, and when breathing is stopped, it stimulates the nerve that stimulates contraction of the diaphragm similar to normal breathing.. The FDAs approval is based on a clinical trial involving 151 patients across Germany, Poland, and the USA. The study assessed the effectiveness of the device in ...
Introduction. In patients with heart failure (HF) and central sleep apnea syndrome (CSAS) different therapeutic options, such as continuous positive airway pressure (CPAP), bi-level PAP (BiPAP) and adaptive servoventilation (ASV) are available. All are potentially effective in improving heart function and in reducing apnea-hypopnea index (AHI), while ASV is generally considered to be most effective.. Aim. To assess how HF-patients with CSAS (AHI ≥15) respond to the different treatments in terms of AHI.. Methods. CPAP was given first, and when ineffective or when patients still experienced SAS related complaints, followed by BiPAP and/or ASV. Efficacy was assessed by a sleep study under treatment. Treatment was considered effective when AHI reduced ,15/hour or reduced at least 50% from the baseline AHI to a value ,20/hour.. Results. 14 males (70 y) were assessed. ...
ResMed studies connect the dots on central sleep apnea | HME News
SAN DIEGO - People with treatment-emergent central sleep apnea (CSA) have a significantly greater risk of terminating CPAP therapy, according to a new ResMed-sponsored study presented on May 22 at the 2017 American Thoracic Society International Conference. Researchers found that 3.5% of patients had CSA during the first 90 days of therapy. ResMed says the study highlights the importance of regularly monitoring patients to support adherence to treatment, and diagnosing CSA early to minimize risk of therapy termination. The study builds on another study released earlier this year that showed patients with treatment-emergent CSA who switch treatment from CPAP therapy to adaptive servo-ventilation therapy use their therapy longer and have significantly fewer apneas during sleep. This study provides the most robust view available on the prevalence of CSA in patients on PAP therapy, said Dr. Carlos Nunez, ResMeds chief medical officer. The findings in this new research, combined with the research ...
China PVC Sterilized Nasal Oxygen Tube for Adult - China Nasal Oxygen Cannula Catheter, Sterile Medical Nasal Cannula
China PVC Sterilized Nasal Oxygen Tube for Adult, Find details about China Nasal Oxygen Cannula Catheter, Sterile Medical Nasal Cannula from PVC Sterilized Nasal Oxygen Tube for Adult - Qingdao Carong Import & Export Co., Ltd.
Possible treatment for central sleep apnea | Apnea Board
If you have Central Sleep Apnea (CSA) or know of someone who has it, then this thread may be of help. A brief internet search on the causes of CSA will return things like; drug induced breathing probl
Obstructive and Central Sleep Apnea: Causes and Risk Factors - Healthvigil
Obstructive and central sleep apnea have different causes and risk factors in children and adults, men and women. They are explained with reason.
CENTRAL SLEEP APNEA (CSA): SYMPTOMS, CAUSES, AND TREATMENT OPTIONS | Respicardia
Important safety information. The remedē® System is indicated for moderate to severe Central Sleep Apnea in adult patients.. Your doctor will need to evaluate your condition to determine if the remedē system is right for you. You will not be able to have an MRI or diathermy (special heat therapies) if you have the remedē system implanted. The remedē® System may be used if you have another stimulation device such as a heart pacemaker or defibrillator; special testing will be needed to ensure the devices are not interacting.. As with any surgically implanted device, there are risks related to the surgical procedure itself which may include, but are not limited to, pain, swelling, and infection.. Once the therapy is turned on, some patients may experience discomfort from stimulation and/or from the presence of the device. The majority of these events are resolved either on their own or by adjusting the therapy settings. The remedē® System may not work for everyone. There are additional ...
AirSense 10 Elite
An advanced fixed-pressure sleep apnoea therapy device with optional integrated humidifier. Built-in wireless connectivity. Cheyne-Stokes and central sleep apnoea detection. Features AutoRamp.
Nasal Oxygen Tubes Market Research: Global Status & Forecast by Geography, Type & Application (2017-2027) - Reports N Markets -...
According to 99Strategy, the Global Nasal Oxygen Tubes Market is estimated to reach xxx million USD in 2021 and projected to grow at the CAGR of xx% during the 2022-2027. The report analyses the global Nasal Oxygen Tubes market, the market size and growth, as well as the major market participants. The analysis includes market size, upstream situation, market segmentation, market segmentation, price & cost and industry environment. In addition, the report outlines the factors driving industry growth and the description of market channels.The report begins from overview of industrial chain structure, and describes the upstream. Besides, the report analyses market size and forecast in different geographies, type and end-use segment, in addition, the report introduces market competition overview among the major companies and companies profiles, besides, market price and channel features are covered in the report. Key Regions Asia Pacific North America Europe South America Middle East &
Do You Want to Be Awake For Your Death? - The Atlantic
My father was put into hospice, and all his meds were stopped. He recovered and lived another six months. After they kicked him out of hospice, he and I spent a lot of quality time together. When the end came, he was ready even though he could no longer speak. The hospice nurse came and looked at all the meds and found that while we still had the liquid morphine, we no longer had the Ativan, so we ordered a stat delivery from the pharmacist.. Giving morphine to a dying person can feel a lot like murder, and listening to the death rattle is more distressing than listening to a crying infant, but I think that the death experience is far worse for the person attending the death than for the one who is dying.. The Ativan was given to my father late in this process, but that was the drug which provided him with joy and relief. Shortly after he received the drug, I believe I witnessed him greeting his mother who had died 40 years ago.. My father then developed what is called a Cheyne-Stokes ...
Patent US8983611 - Neural control of central sleep apnea - Google Patentsuche
An apparatus comprises a physiologic sensing circuit and a control circuit. The physiologic sensing circuit is configured to sense an electrical respiration signal representative of respiration of a subject. The control circuit includes a respiration monitor circuit and a therapy circuit. The respiration monitor circuit is configured to extract a respiration parameter from the respiration signal and detect that a value of the respiration parameter is outside of a target value range for the respiration parameter. The therapy circuit is configured to deliver neural stimulation to the carotid sinus of the subject to stimulate respiration and to adjust respiration to maintain the value of the respiration parameter within the target value range.
crippling obstructive/central sleep apnea | Phoenix Rising ME / CFS Forums
does anyone have treatments for central apnea? Its really dangerous and damaging if your O2 levels fall to 70%. I think my problem is my sleep is...
DS-8 BiPAP Non-invasive Ventilator - Medical Mart
BiPAP is a method of breathing support that is often used to treat central sleep apnea and central sleep apnea(both OSA and CSA), but its not used for life support. Many of the components of a BiPAP machine are the same as the standard CPAP machine. It can provide the correct airway pressure to prevent…
Dr Krishna Sundar Differentiates Between Obstructive, Central Sleep Apnea | AJMC
Much of the population experiences disordered breathing at night, explained Krishna M. Sundar, MD, clinical professor, Pulmonary Division, Department of Medicine, and medical director, Sleep-Wake Center, University of Utah.
UCHealth first in region to offer latest technology for central sleep apnea | Respicardia
By: Kelly Tracer, UCHealth LOVELAND, Colo. (April 4, 2019) - UCHealth is the first health system in the Rocky Mountain region to offer the latest, implantable
In pure central sleep apnea or Cheyne-Stokes respiration, the brain's respiratory control centers are imbalanced during sleep. ... Yumino D, Bradley TD (February 2008). "Central sleep apnea and Cheyne-Stokes respiration". Proceedings of the American Thoracic ... Cheyne-Stokes Respiration". Sleep. 29 (8): 1045-1051. doi:10.1093/sleep/29.8.1045. PMID 16944673. Vennelle M, White S, Riha RL ... The Inspire Upper Airway Stimulation system senses respiration and applies mild electrical stimulation during inspiration, ...
Obstructive sleep apnea
Cheyne-Stokes respiration". Sleep. 29 (8): 1045-51. doi:10.1093/sleep/29.8.1045. PMID 16944673. Caba, Justin (16 April 2015). " ... The second and third criteria are about respiration - waking with breath holding, gasping, or choking ; snoring, breathing ... Randomized controlled studies of the efficacy of UPPP are published, showing effect on nocturnal respiration and excessive ... thoraco-abdominal paradoxical respiration during the event. If none of them are present during the event, then it is ...
Abnormal breathing patterns include Kussmaul breathing, Biot's respiration and Cheyne-Stokes respiration. Other breathing ... Medicine portal Agonal respiration - Abnormal pattern of breathing (not related to death rattle) Ataxic respiration Bad breath ... Breathing, or "external respiration", brings air into the lungs where gas exchange takes place in the alveoli through diffusion ... All aerobic creatures need oxygen for cellular respiration, which uses the oxygen to break down foods for energy and produces ...
Death of Gloria Ramirez
She was extremely confused and was suffering from tachycardia and Cheyne-Stokes respiration. The medical staff injected her ...
Cheyne-Stokes respiration is a breathing pattern consisting of alternating periods of rapid and slow breathing, which may ... Cheyne-Stokes respiration may be observed in newborn babies, but this is occasionally physiological (normal). Chest retractions ... Rudrappa, Mohan; Bollu, Pradeep C. (2019), "Cheyne Stokes Respirations", StatPearls, StatPearls Publishing, PMID 28846350, ... aid in respiration. These are signs of respiratory distress. The physician then typically inspects the fingers for cyanosis and ...
Central sleep apnea
Adults suffering from congestive heart failure are at risk for a form of central apnea called Cheyne-Stokes respiration, which ... Cheyne-Stokes respiration is characterized by periodic breathing featuring recurrent episodes of apnea alternating with ... Cheyne-Stokes respiration, High-altitude periodic breathing, CSA due to a medical condition without CSB, Central sleep apnea ... CSA with Cheyne-Stokes breathing is characterized by at least one of the criteria of Primary CSA or the presence of atrial ...
Cheyne-Stokes respiration - Abnormal breathing pattern, another condition involving oxygen / carbon dioxide imbalance and which ...
He was confined to bed for a month, with death for a time seeming close as he began suffering from Cheyne-Stokes respiration. ...
Obstructive sleep apnea
Cheyne-Stokes respiration". Sleep. 29 (8): 1045-51. PMID 16944673.. *^ "Learning To Play A Wind Instrument Could Lower Your ... blocking ports of airflow and hindering effective respiration. There have been documented instances of severe airway ... Food and Drug Administration in 2014 granted pre-market approval for an upper airway stimulation system that senses respiration ... recurrent interruptions of respiration during sleep are associated with temporary airway obstruction. Following pharyngeal flap ...
George N. Kennedy
He died from "brain disease and Cheyne-Stokes respiration" at his summer residence in Thousand Island Park, and was buried at ...
Respiratory inductance plethysmography
... expiratory lung volume is a change in the level of end expiratory lung volume and may be elevated in Cheyne-Stokes respiration ... The electronics convert this change in frequency to a digital respiration waveform where the amplitude of the waveform is ... However, accuracy issues arise when trying to assess accurate respiratory volumes from a single respiration band placed either ... This further limits quantification of many useful respiratory indices and limits utility to only respiration rates and other ...
... a medical condition involving hyperventilating Cheyne-Stokes respiration, the breathing disorder Hypocapnia, a physiological ...
Index of anatomy articles
... cervical sympathetic ganglia cervical vertebrae cervicothoracic ganglion cervix chaetae cheek chest Cheyne-Stokes respiration ...
If any of these deviate from normal, this may indicate an underlying problem (such as with Cheyne-Stokes respiration) Chest ... such as artificial respiration. Rescuers are often warned against mistaking agonal breathing, which is a series of noisy gasps ... "A comparison of the mouth to mouth and mouth to airway methods of artificial respiration with chest pressure arm lift methods ... Cardiopulmonary resuscitation Artificial respiration Recovery position First aid Wright, Pearce (2003-08-13). "Obituary: Peter ...
... may refer to: Central serous retinopathy, a visual impairment Cheyne-Stokes respiration, an abnormal respiration pattern ...
List of MeSH codes (C23)
... cheyne-stokes respiration MeSH C23.888.852.293 - cough MeSH C23.888.852.371 - dyspnea MeSH C23.888.852.371.396 - dyspnea, ... adams-stokes syndrome MeSH C23.550.073.425.100 - bundle-branch block MeSH C23.550.073.425.780 - sinoatrial block MeSH C23.550. ...
List of Scots
... identified Cheyne-Stokes respiration, with William Stokes Colin Chisholm (1755-1825), surgeon, medical writer and Fellow of the ... pioneer of First aid John Cheyne (1777-1836), physician, and medical writer; ...
George Alexander Gibson
The Old Red Sandstone of Shetland (1877) Cheyne-Stokes Respiration (1892) Diseases of the Heart and Aorta (1898) Edinburgh: ... Medical Bibliography for 1877 Gibson, G.A. (14 October 2010) . Cheyn Stoke Respiration. Nabu Press. ISBN 978-1172128976. ...
... and respiratory abnormalities such as Cheyne-Stokes respiration (cyclic waxing and waning of tidal volume), apneustic ... respirations and post-hypercapnic apnea. Focal neurological deficits are less common. Wernicke encephalopathy can co-occur with ...
Syndrome of inappropriate antidiuretic hormone secretion
... muscle weakness Myoclonus Decreased reflexes Ataxia Pathological reflexes Tremor Asterixis Cheyne-Stokes respiration Dysarthria ...
"Cheyne-Stokes respiration", "Kaplan-Meier method"), and so on. In English, the en dash is usually used instead of a hyphen in ...
Apnea Dyspnea Hyperpnea Tachypnea Hypopnea Bradypnea Orthopnea Platypnea Biot's respiration Cheyne-Stokes respiration Kussmaul ... Respiration rates may increase with fever, illness, or other medical conditions. Inaccuracies in respiratory measurement have ...
In common medical practice, Biot's respiration is often clinically equivalent to Cheyne-Stokes respiration, although the two ... Contribution a l'étude du phénomène respiratoire de Cheyne-Stokes. Lyon Med. 1876;23:517-528, 561-567. Wijdicks EF (May 2007 ... Biot's respiration is caused by damage to the pons due to strokes or trauma or by pressure on the pons due to uncal or ... Biot's respiration is an abnormal pattern of breathing characterized by groups of regular deep inspirations followed by regular ...
John Cheyne (physician)
He was one of the people to identify Cheyne-Stokes respiration. He was born in Leith, the son of Dr John Cheyne, a surgeon. The ... Pearce, J M S (May 2002). "Cheyne-Stokes respiration". J. Neurol. Neurosurg. Psychiatry. 72 (5): 595. doi:10.1136/jnnp.72.5.595 ... Sternbach, G L (1985). "John Cheyne and William Stokes: periodic respiration". The Journal of Emergency Medicine. 3 (3): 233-6 ... Cheyne and Stokes?". Nursing Times. 91 (14): 40. PMID 7731827. Lyons, J B (March 1995). "John Cheyne's classic monographs". ...
"Cheynes-Stokes Respiration". WebMD LLC. Retrieved 2010-10-05. "Cheyne-Stokes respiration". WrongDiagnosis.com. Health Grades ... Cheyne-Stokes respirations are not the same as Biot's respirations ("cluster breathing"), in which groups of breaths tend to be ... Thus Cheyne-Stokes respiration can be maintained over periods of many minutes or hours with a repetitive pattern of apneas and ... Cheyne-Stokes respiration and periodic breathing are the two regions on a spectrum of severity of oscillatory tidal volume. The ...
... external respiration and internal respiration. *Cheyne-Stokes respiration, an abnormal pattern of breathing characterized by ... Anaerobic respiration, cellular respiration without oxygen. *Maintenance respiration, the amount of cellular respiration ... Aquatic respiration, animals extracting oxygen from water. *Artificial respiration, the act of simulating respiration, which ... This disambiguation page lists articles associated with the title Respiration. If an internal link led you here, you may wish ...
... external respiration and internal respiration Cheyne-Stokes respiration, an abnormal pattern of breathing characterized by ... Anaerobic respiration, cellular respiration in the absence of oxygen. Three common anaerobic respirations include alcohol ... Respiration may refer to: Cellular respiration, the process in which nutrients are converted into useful energy in a cell while ... Maintenance respiration, the amount of cellular respiration required for an organism to maintain itself in a constant state ...
... descended from the surgeon and bacteriologist Sir William Cheyne (1852-1932) Cheyne Walk Cheyne-Stokes respiration, a medical ... John Cheyne, Baron Cheyne (c1445-1499), English courtier and hostage after the Treaty of Picquigny (1475) John Cheyne ( ... William Cheyne (footballer) (1912-1988), also known as Andy Cheyne, Scottish footballer (Rangers) Given name: Cheyne Coates, ... 13thc.), Lord Chamberlain of Scotland Thomas Cheney (Cheyne) (c1485-1558), Lord Warden of the Cinque Ports Thomas Kelly Cheyne ...
Agonal respiration. *Biot's respiration. *Cheyne-Stokes respiration. *Kussmaul breathing. *Ataxic respiration. Other. * ...
Agonal respiration. *Biot's respiration. *Cheyne-Stokes respiration. *Kussmaul breathing. *Ataxic respiration. Other. * ... Thus, the hiccup is evolutionarily antecedent to modern lung respiration. Additionally, this group (C. Straus et al.) points ... and Japan proposed that the hiccup is an evolutionary remnant of earlier amphibian respiration. Amphibians such as tadpoles ...
呼吸 - 维基百科，自由的百科全书
切恩-斯托克斯氏呼吸（英语：Cheyne-Stokes respiration） ... The capture of oxygen: Respiration. Biology 8th. McGraw-Hill Science/Engineering/Math;. 2007. ISBN 0-07-322739-0.. ... 瀕死呼吸（英语：Agonal respiration）. * ...
Shortness of breath
Agonal respiration. *Biot's respiration. *Cheyne-Stokes respiration. *Kussmaul breathing. *Ataxic respiration. Other. * ... it is able to compare it to the current level of respiration as determined by the efferent signals. If the level of respiration ...
Agonal respiration. *Biot's respiration. *Cheyne-Stokes respiration. *Kussmaul breathing. *Ataxic respiration. Other. * ...
Agonal respiration. *Biot's respiration. *Cheyne-Stokes respiration. *Kussmaul breathing. *Ataxic respiration. Other. * ...
Agonal respiration. *Biot's respiration. *Cheyne-Stokes respiration. *Kussmaul breathing. *Ataxic respiration. Other. * ... It can occur with or without an increase in respiration rate. It is characterized by deep breathing. It may be ... Hyperpnea (forced respiration) is increased volume of air during breathing. ... which involves an increase in volume and respiration rate, resulting in rapid and deep breaths. ...
ഫലകം:Respiratory system symptoms and signs - വിക്കിപീഡിയ
Agonal respiration. *Biot's respiration. *Cheyne-Stokes respiration. *Kussmaul breathing. *Ataxic respiration. Other. * ... Stridor heard solely in the expiratory phase of respiration usually indicates a lower respiratory tract obstruction, "as with ... Bronchiolar disease usually causes wheezing that occurs in the expiratory phase of respiration. As a rule, extrathoracic airway ...
Agonal respiration. *Biot's respiration. *Cheyne-Stokes respiration. *Kussmaul breathing. *Ataxic respiration. Other. * ... Acute cyanosis can be as a result of asphyxiation or choking, and is one of the definite signs that respiration is being ...
呼吸急促 - 维基百科，自由的百科全书
Biot's respiration（英语：Biot's respiration）. *Cheyne-Stokes respiration（英语：Cheyne-Stokes respiration） ...
ഇക്കിൾ - വിക്കിപീഡിയ
Claude Gordon Douglas
with John Scott Haldane: Douglas CG, Haldane JS (1909). "The causes of periodic or Cheyne-Stokes breathing". The Journal of ... From 1908 to 1914, Douglas did research with John Scott Haldane on human respiration. In 1910 Nathan Zuntz organised a high- ... After 1920 the work of Douglas and his research students dealt mainly with the effects of exercise on respiration, metabolism, ...
List of medical mnemonics
Diarrhea Urination Miosis Bradycardia Bronchospasm Emesis Lacrimation Loss of muscle strength Salivation/sweating Cheyne-Stokes ... respiration (used to assess newborn babies) ASHICE - age, sex, history, injuries/illness, condition, ETA/extra information FAST ... Thirst Vomitting Sweating Pulse weak Anxious Respirations shallow/rapid Cool Cyanotic Unconscious BP low Eyes blank RN CHAMPS ( ...
Cheyne-Stokes respiration - Wikipedia
"Cheynes-Stokes Respiration". WebMD LLC. Retrieved 2010-10-05. "Cheyne-Stokes respiration". WrongDiagnosis.com. Health Grades ... Cheyne-Stokes respirations are not the same as Biots respirations ("cluster breathing"), in which groups of breaths tend to be ... Thus Cheyne-Stokes respiration can be maintained over periods of many minutes or hours with a repetitive pattern of apneas and ... Cheyne-Stokes respiration and periodic breathing are the two regions on a spectrum of severity of oscillatory tidal volume. The ...
Cheyne-Stokes respiration: Symptoms, management, and prevention
Cheyne-Stoke respiration is believed to be more common during sleep. It is serious and often develops in people who have heart ... This MNT Knowledge Center article looks at an abnormal breathing pattern called Cheyne-Stoke respiration, including its ... Who is at risk of Cheyne-Stokes respiration?. Cheyne-Stokes respiration can occur in people with neurological conditions, or ... Cheyne-Stokes respiration, also known as periodic respiration, is an abnormal pattern of breathing. It consists of cycles of ...
Cheyne-Stokes respiration | Diagnosaurus
Cheyne-Stokes respiration answers are found in the Diagnosaurus powered by Unbound Medicine. Available for iPhone, iPad, ... respiration. Accessed April 21, 2021.. Zeiger, R. F. (2015). Cheyne-Stokes respiration. In Diagnosaurus (4th edition). McGraw- ... respiration. Zeiger RFR. Cheyne-Stokes Respiration [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2015. [cited 2021 April ... Cheyne-Stokes respiration is a topic covered in the Diagnosaurus. To view the entire topic, please log in or purchase a ...
Cheyne-Stokes Respiration Medical Definition | Merriam-Webster Medical Dictionary
... cyclic breathing marked by a gradual increase in the rapidity of respiration followed by a gradual decrease and total cessation ... Share Cheyne-Stokes respiration. Post the Definition of Cheyne-Stokes respiration to Facebook Share the Definition of Cheyne- ... Resources for Cheyne-Stokes respiration. Time Traveler: Explore other words from the year Cheyne-Stokes respiration first ... Comments on Cheyne-Stokes respiration. What made you want to look up Cheyne-Stokes respiration? Please tell us where you read ...
Cheyne-Stokes Respiration - Medical Dictionary / Glossary | Medindia
Cheyne-Stokes Respiration - A pattern of breathing with varying depth of respiration and brief periods of apnea, is clearly ... Medical Word - Cheyne-Stokes Respiration. Ans : A pattern of breathing with varying depth of respiration and brief periods of ... Cheyne-Stokes Respiration - Glossary. Written & Compiled by Medindia Content Team. Medically Reviewed by The Medindia Medical ...
Cheyne-Stokes respiration syndrome - definition of Cheyne-Stokes respiration syndrome by The Free Dictionary
Cheyne-Stokes respiration syndrome synonyms, Cheyne-Stokes respiration syndrome pronunciation, Cheyne-Stokes respiration ... Cheyne-Stokes respiration syndrome. Translations. English: Cheyne-Stokes respiration syndrome n. síndrome de respiración de ... English dictionary definition of Cheyne-Stokes respiration syndrome. ... Cheyne-Stokes respiration syndrome. Translations. Cheyne-Stokes respiration syndrome n. síndrome de respiración de Cheyne- ...
Cognitive impairment in heart failure with Cheyne-Stokes respiration.
... and to determine its relation to the presence of Cheyne-Stokes respiration during sleep. SUBJECTS: 104 heart failure patients ... Cheyne-Stokes Respiration / complications*. Cognition Disorders / diagnosis*, etiology*. Echocardiography. Heart Failure / ... METHODS: Overnight oximetry was used (previously validated as a screening tool for Cheyne-Stokes respiration in heart failure ... Vigilance was impaired in heart failure but this did not appear to be related to the presence of Cheyne-Stokes respiration ...
Cognitive impairment in heart failure with Cheyne-Stokes respiration | Heart
Cheyne-Stokes respiration is usually defined as crescendo-decrescendo periodic respiration with a central apnoea index of ⩾ 10/ ... DIAGNOSIS OF CHEYNE-STOKES RESPIRATION. All subjects underwent overnight oximetry in their own homes using the Ohmeda Biox 3700 ... The effect of Cheyne-Stokes respiration on cognitive function in heart failure has not previously been investigated. We were ... We reasoned that Cheyne-Stokes respiration during sleep might lead to cognitive dysfunction as a result of either apnoea ...
Cardiovascular Responses in Congestive Heart Failure With Cheyne- Stokes Respiration - Full Text View - ClinicalTrials.gov
Cheyne-Stokes Respiration. Heart Diseases. Cardiovascular Diseases. Respiration Disorders. Respiratory Tract Diseases. Signs ... Cardiovascular Responses in Congestive Heart Failure With Cheyne- Stokes Respiration. The safety and scientific validity of ... Cardiovascular Response to Peripheral Chemoreceptor Stimulation in Congestive Heart Failure With Cheyne- Stokes Respiration. ... is to investigate the cardiovascular response to peripheral chemoreceptor stimulation in Congestive Heart Failure with Cheyne- ...
Is Cheyne-Stokes respiration friend or foe of heart failure? | Thorax
Cheyne-Stokes respiration: friend or foe? in his recent opinion in Thorax.1 Central sleep apnoea with Cheyne-Stokes ... Doppler evaluation of changing cardiac dynamics during Cheyne-Stokes Respiration. BMJ 1989;95:525-9. ... Polygraphic recordings showing Central sleep apnoea with Cheyne-Stokes respiration in a heart failure (HF) patient (A) and ... respiration (CSA-CSR) indeed has multiple features more likely to be compensatory than injurious in heart failure (HF). His ...
Synonyms and Antonyms for cheyne-stokes-respiration | Synonym.com
1. Cheyne-Stokes respiration (n.). abnormal respiration in which periods of shallow and deep breathing alternate ... 6. respiration (n.). the bodily process of inhalation and exhalation; the process of taking in oxygen from inhaled air and ... 2. Stokes-Adams syndrome (n.). recurrent sudden attacks of unconsciousness caused by impaired conduction of the impulse that ... 3. stokes aster (n.). erect perennial of southeastern United States having large heads of usually blue flowers ...
cheyne-stokes respiration meaning in English - EnglishLearner
... derived terms and more about the word cheyne-stokes respiration. ... Meaning of Cheyne-Stokes respiration in English. Table of ... Definition of cheyne-stokes respiration, with etymology, pronunciation (phonetic and audio), synonyms, antonyms, ... Cheyne-Stokes respiration. Definitions. 1. abnormal respiration in which periods of shallow and deep breathing alternate ... How to pronounce cheyne-stokes respiration in American English, in context ▾. Use the controls below to browse different ...
Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration | Annals of Internal Medicine | American College of Physicians
Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration: A Case Report Theophylline Therapy for Near-Fatal Cheyne-Stokes ... Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration Don D. Sin, MD, MPH; T. Douglas Bradley, MD ... However, we believe that the use of the term "Cheyne-Stokes respiration" to describe their patients respiratory disorder was ... As the authors note, Cheyne-Stokes respiration is characterized by periodic breathing in which apneas or hypopneas alternate ...
Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration | Annals of Internal Medicine | American College of Physicians
Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration: A Case Report Theophylline Therapy for Near-Fatal Cheyne-Stokes ... Somers VK, Pesek C. Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration. Ann Intern Med. 1999;131:714. doi: 10.7326/ ... Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration Virend K. Somers, MD, PhD; Catherine Pesek, DO ... and Bradley and Geigel and Chediak point out that the respiratory tracings do not represent classic Cheyne-Stokes respiration ( ...
Swiss Medical Weekly - Cheyne-Stokes respiration in patients with heart failure: ominous sign or innocent bystander?
Continuous Positive Airway Pressure in Patients With Congestive Heart Failure and Cheyne-Stokes Respiration With Central Sleep...
Treatment of congestive heart failure and Cheyne-Stokes respiration during sleep by continuous positive airway pressure. Am J ... Continuous Positive Airway Pressure in Patients With Congestive Heart Failure and Cheyne-Stokes Respiration With Central Sleep ... Continuous Positive Airway Pressure in Patients With Congestive Heart Failure and Cheyne-Stokes Respiration With Central Sleep ... Continuous Positive Airway Pressure in Patients With Congestive Heart Failure and Cheyne-Stokes Respiration With Central Sleep ...
Cheyne-Stokes respiration - How is Cheyne-Stokes respiration abbreviated?
Looking for abbreviations of CSR? It is Cheyne-Stokes respiration. Cheyne-Stokes respiration listed as CSR ... Cheyne-Stokes respiration - How is Cheyne-Stokes respiration abbreviated? https://acronyms.thefreedictionary.com/Cheyne-Stokes+ ... redirected from Cheyne-Stokes respiration). Also found in: Dictionary, Thesaurus, Medical, Legal, Encyclopedia, Wikipedia. ... Finally, in a recent study, we aimed to evaluate acute effects of adaptive servo ventilation (ASV) on Cheyne-Stokes respiration ...
Cheyne-Stokes respiration is not related to quality of life or sleepiness in heart failure
... Midgren, Bengt ... Conclusions: Cheyne-Stokes respiration was not associated with health-related quality of life, daytime sleepiness or nocturnal ... Background and aims: The effects of central sleep apnea in Cheyne-Stokes respiration on sleep-related symptoms and quality of ... We aimed to investigate whether Cheyne-Stokes respiration is related to health-related quality of life. We also studied the ...
Influence of adaptive servoventilation therapy on autonomic function and baroreceptor reflex sensitivity in heart failure...
ASV treatment in HF patients with Cheyne-Stokes respirations leads to an increase in SV likely mediated by a decrease in ... 12 patients with HF (12 male; 70 ± 9 years; NYHA ≥ II; EF ≤ 45% and Cheyne- Stokes respiration) and 14 healthy volunteers (13 ... Adaptive servoventiation therapy (ASV) is designed to treat hypocapnic central sleep apnoea (Cheyne-Stokes respiration) in ... therapy on autonomic function and baroreceptor reflex sensitivity in heart failure patients with Cheyne-Stokes respiration ...
Cheyne-stokes respiration in patients with heart failure: prevalence, causes, consequences and treatments - Zurich Open...
Cheyne-stokes respiration in patients with heart failure: prevalence, causes, consequences and treatments. Respiration, 83(2): ... Cheyne-Stokes respiration (CSR) is characterized by a pattern of cyclic oscillations of tidal volume and respiratory rate with ... Cheyne-Stokes respiration (CSR) is characterized by a pattern of cyclic oscillations of tidal volume and respiratory rate with ... Cheyne-stokes respiration in patients with heart failure: prevalence, causes, consequences and treatments ...
Leicester Research Archive: Cerebral Hemodynamic Effects of Cheyne-Stokes Respiration in a Patient with Stroke
INTRODUCTION: Cheyne-Stokes respiration (CSR) and central sleep apnea (CSA) are common in patients with heart failure and/or ... Cerebral hemodynamic effects of Cheyne-Stokes respiration Accepted Version.pdf. Post-review (final submitted author manuscript) ... Cerebral Hemodynamic Effects of Cheyne-Stokes Respiration in a Patient with Stroke. ...
Cheyne - Stokes Respiration | Patterns Of Cheyne-Stokes Respiration | Heart Failure And Cheyne-Stokes Respiration
Day time sleep also results with cheyne-stokes respiration. Patterns of cheyne-stokes respiration:. Cheyne-stokes respiration ... Cheyne - Stokes Respiration , Patterns Of Cheyne-Stokes Respiration , Heart Failure And Cheyne-Stokes Respiration. ... Stokes Respiration , Patterns Of Cheyne-Stokes Respiration , Heart Failure And Cheyne-Stokes Respiration ... Cheyne-Stokes Respiration. Cheyne-stokes respiration is an abnormal pattern of breathing which occurs in patients with ...
Cheyne Stokes Respirations Article - StatPearls
Cheyne Stokes Respirations. Introduction. Cheyne-Stokes respiration is a type of breathing disorder characterized by cyclical ... Cheyne-Stokes respiration is believed to be a result of heart failure. The presence of Cheyne-Stokes respiration in patients ... Cheyne-Stokes respiration is believed to be a result of heart failure. The presence of Cheyne-Stokes respiration in patients ... and increased plasma catecholamines compared to patients without Cheyne-Stokes respiration.. Cheyne-Stokes respiration is a ...
Cardiac resynchronization therapy improves central sleep apnea and Cheyne-Stokes respiration in patients with chronic heart...
... leading to Cheyne-Stokes respiration, and not vice versa.. Elevated Ve/Vco2slopes (19)and Cheyne-Stokes respiration (2)are ... Based on our findings, the improvement of CSA with Cheyne-Stokes respiration could be used as a helpful tool to evaluate the ... 1998) The development of hyperventilation in patients with chronic heart failure and Cheyne-Stokes respiration. Chest 114:1083- ... Of these, 14 showed evidence of CSA and Cheyne-Stokes respiration. All patients presented with heart failure of New York Heart ...
Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration
Treatment of Cheyne-Stokes respiration-central sleep apnea in patients with heart failure.. Momomura S., J Cardiol 59(2), 2012 ... Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration. Bitter T, Westerheide N, Faber L, Hering D ... Predictors of oxidative stress in heart failure patients with Cheyne-Stokes respiration.. Krieger AC, Green D, Cruz MT, ... A high prevalence of nocturnal Cheyne-Stokes respiration (CSR) has been documented in patients with heart failure with normal ...
Central Sleep Apnea Syndrome (Idiopathic CSA, Cheyne-Stokes Respiration, CSA due to a drug or substance, High-altitude Periodic...
Cheyne-Stokes Respiration (CSR) and CSA associated with CHF: In comparison with the other types of CSA, when associated with ... "Cheyne-Stokes respiration in stroke: relationship to hypocapnia and occult cardiac dysfunction". Am J Respir Crit Care Med. vol ... Cheyne-Stokes Respiration (CSR): CSR is a breathing pattern characterized by cycles of crescendo-decrescendo changes in tidal ... "Increased mortality associated with Cheyne-Stokes respiration in patients with congestive heart failure". Am J Respir Crit Care ...
Cheyne-Stokes respiration | Taber's Medical Dictionary
Cheyne-Stokes respiration answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone ... respiration. Cheyne-Stokes respiration. In: Venes D, ed. Tabers Medical Dictionary. 23rd ed. F.A. Davis Company; 2017. https ... respiration. Cheyne-Stokes Respiration [Internet]. In: Venes D, editors. Tabers Medical Dictionary. F.A. Davis Company; 2017 ... respiration. Accessed January 20, 2020.. Cheyne-Stokes respiration. (2017). In Venes, D. (Ed.), Tabers Medical Dictionary. ...
Cheyne-Stokes respiration is not related to quality of life or sleepiness in heart failure - Lunds universitet
Cheyne-Stokes respiration is not related to quality of life or sleepiness in heart failure. Forskningsoutput: Tidskriftsbidrag ... Please cite this paper as: Midgren B, Mared L, Franklin KA, Berg S, Erhardt L and Cline C. Cheyne-Stokes respiration is not ... Conclusions: Cheyne-Stokes respiration was not associated with health-related quality of life, daytime sleepiness or nocturnal ... Background and aims: The effects of central sleep apnea in Cheyne-Stokes respiration on sleep-related symptoms and quality of ...
Cheyne-Stokes respiration • LITFL
Cheyne-Stokes Respiration] [Reprinted: Cardiac Classics. 1941;1:317-320]. *Stokes W. Fatty degeneration of the heart. In: The ... 1953 - On March 4th 1953, the Soviet press announced that Joseph Stalin was ill and had Cheyne-Stokes respiration. The ... Cheyne J. A case of apoplexy in which the fleshy part of the heart was converted into fat. Dublin Hospital Reports. 1818;2:216- ... Cheyne-Stokes respiration. *Dr Sam Khor. *. Jun 27, 2019. Home. LITFL. Eponymictionary Description. Cheyne-Stokes respiration ...
William StokesCongestiveCarbon dioxidePresence of Cheyne-Stokes respRespiratoryApnoeaApnea syndromeSyndromeTaber's Medical DictionaryHyperventilationCardiacPeriodic respirationApneasSymptomsHeartPeriods of apneaDefinitionBreathingHyperpnoeicPattern of respiration1937PrevalenceCell respirationCentralOccursLeithDiseasesDublin Hospital ReportsChestUnboundmedicine.comAcuteStroke
- Although described in the early 19th century by John Cheyne and William Stokes, this disorder has received considerable attention in the last decade due to its association with heart failure and stroke, two major cause of mortality and morbidity in developed countries. (statpearls.com)
- Cheyne-Stokes or Hunter-Cheyne-Stokes breathing was first defined in the 1800s by 2 physicians: Dr. John Cheyne and Dr. William Stokes. (verywellhealth.com)
- The display shows on the left a portrait of John Cheyne and on the right is a portrait of William Stokes with a sample trace of Cheyne-Stokes respiration between them. (blogspot.com)
- William Stokes (1804 -1878) is regarded as one of the greatest teachers of clinical medicine. (blogspot.com)
- The condition was named after John Cheyne and William Stokes, the physicians who first classified it. (fandom.com)
- Circulation time is increased in people with congestive heart failure and Cheyne-Stokes respiration. (medicalnewstoday.com)
- Cheyne-Stokes respiration can occur in people with neurological conditions, or congestive heart failure. (medicalnewstoday.com)
- Some research estimates that 50 percent of all people who have moderate to severe congestive heart failure also have significant Cheyne-Stokes respiration. (medicalnewstoday.com)
- The article by Sin et al 1 on the effect and outcome of continuous positive airway pressure (CPAP) in patients with congestive heart failure (CHF) who have Cheyne-Stokes respiration with central sleep apnea (CSR-CSA) is one more step toward further defining the role of treatment for sleep-disordered breathing in CHF. (ahajournals.org)
- However, we are presently conducting a long-term, multicenter, randomized trial of continuous positive airway pressure (CPAP) in patients with congestive heart failure (CHF) and Cheyne-Stokes respiration with central sleep apnea (CSR-CSA), the Canadian Positive Airway Pressure for Heart Failure (CANPAP) trial, with cardiac transplant-free survival as the primary outcome. (ahajournals.org)
- Cheyne-Stokes respiration was not associated with health-related quality of life, daytime sleepiness or nocturnal dyspnea among patients stabilized following treatment for congestive heart failure. (diva-portal.org)
- Cheyne-stokes respiration is an abnormal pattern of breathing which occurs in patients with congestive heart failure, neurological diseases, and central sleep apnea. (sleepdisordersguide.com)
- Cheyne-Stokes breathing is fairly common among people with congestive heart failure and is considered a poor prognostic sign, That said, some people with Cheyne-Stokes breathing secondary to heart failure go on to live for a long period of time. (verywellhealth.com)
- Treatment of congestive heart failure and Cheyne-Stokes respiration during sleep by continuous positive airway pressure. (freethesaurus.com)
- First experience of using new adaptive servoventilation device for Cheyne-Stokes respiration with central sleep apnoea among Japanese patients with congestive heart failure: report of 4 clinical cases. (freethesaurus.com)
- Cheyne-Stokes respiration (CSR), which often occurs in patients with congestive heart failure (CHF), may be a predictor for poor outcome. (pharmaceuticalintelligence.com)
- Cheyne-Stokes respiration (CSR), a condition characterized by a cyclic pattern of waxing and waning ventilation interposed by central apneas or hypopneas , may affect up to 40% of patients with congestive heart failure (CHF) . (pharmaceuticalintelligence.com)
- Nevertheless, several investigators have reported that CSR might be an independent prognostic index of poor outcome in patients with CHF, so that Cheyne-Stokes respiration (CSR), which often occurs in patients with congestive heart failure (CHF), may be a predictor for poor outcome. (pharmaceuticalintelligence.com)
- As those with Cheyne-Stokes respiration hyperventilate, their total carbon dioxide stores are likely to be reduced, which interferes with the carbon dioxide buffering capacity of the body. (medicalnewstoday.com)
- Cheyne-stokes respiration is caused by the failure of the respiratory center in the brain to compensate quickly for changing serum partial pressure of carbon dioxide and oxygen. (sleepdisordersguide.com)
- In cellular respiration the blood cells release oxygen and pick up carbon dioxide. (thefreedictionary.com)
- Respiration in which an organism, such as a one-celled ameba, secures its oxygen and gives up carbon dioxide directly to the surrounding medium. (tabers.com)
Presence of Cheyne-Stokes resp6
- OBJECTIVES: To document the degree of cognitive impairment in stable heart failure, and to determine its relation to the presence of Cheyne-Stokes respiration during sleep. (biomedsearch.com)
- Cognitive impairment within the heart failure group was unrelated to either the presence of Cheyne-Stokes respiration, the degree of left ventricular dysfunction, or indices of nocturnal oxygenation. (biomedsearch.com)
- CONCLUSIONS: Vigilance was impaired in heart failure but this did not appear to be related to the presence of Cheyne-Stokes respiration during sleep. (biomedsearch.com)
- 5 We hypothesised that the degree of daytime cognitive impairment would be related to the presence of Cheyne-Stokes respiration during sleep. (bmj.com)
- We also investigated the relation between cognitive impairment and indices of nocturnal oxygen desaturation, left ventricular function, and the presence of Cheyne-Stokes respiration. (bmj.com)
- The presence of Cheyne-Stokes respiration in patients with heart failure also predicts worse outcomes and increases the risk of sudden cardiac death. (statpearls.com)
- However, we believe that the use of the term "Cheyne-Stokes respiration" to describe their patient's respiratory disorder was not consistent with the known pathophysiology and clinical description of this term. (annals.org)
- Sin and Bradley and Geigel and Chediak point out that the respiratory tracings do not represent classic Cheyne-Stokes respiration (CSR). (annals.org)
- Cheyne-Stokes respiration (CSR) is characterized by a pattern of cyclic oscillations of tidal volume and respiratory rate with periods of hyperpnea alternating with hypopnea or apnea in patients with heart failure. (uzh.ch)
- Cheyne-Stokes respiration is initiated and maintained due to change in the apnea threshold and the fluctuating PCO2 levels around this threshold in patients with heart failure or stroke who are at risk of unstable central respiratory control. (statpearls.com)
- Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration", EUROPEAN RESPIRATORY JOURNAL , vol. 36, 2010, pp. 385-392. (uni-bielefeld.de)
- In a lot of these patients it is neither a purely obstructive sleep-apnea syndrome nor a complete Cheyne-Stokes-respiration but a combination of both sleep related respiratory disturbances. (clinicaltrials.gov)
- Previous studies showed an improvement of the central respiratory disorder, for example Cheyne-Stokes-respiration, under continuous positive pressure breathing (CPAP) and an improvement of the left ventricular pump function. (clinicaltrials.gov)
- Respiration in which respiratory sounds are suppressed or absent. (tabers.com)
- Aim: To analyze the relationship between daytime respiratory and cardiac function in patients with compensated chronic heart failure (CHF) with and without periodic breathing (PB) or Cheyne-Stokes respiration (CSR). (elsevier.com)
- Cheyne-stokes respiration is an abnormal breathing pattern where the patient has very deep breathing (sometimes with increased respiratory rate) that gradually slows down until the patient stops breathing, and the cycle repeats (usually over a 30-120 second cycle). (healthtap.com)
- Idiopathic Cheyne-Stokes respiration in acute respiratory acidosis. (nih.gov)
- According to the clinical criteria, the patients were classified into the follow groups: 19 patients with nPB pattern, 7 with PB pattern, 4 with Cheyne-Stokes respiration (CSR), and 6 non-classified patients (problems with respiratory signal). (ibecbarcelona.eu)
- A diaphragm pacing stimulatory method and a system to implement the method are provided to improve respiratory function and the quality of sleep in patients whose sleep is compromised by poor respiration. (google.es)
- 1 Central sleep apnoea with Cheyne-Stokes respiration (CSA-CSR) indeed has multiple features more likely to be compensatory than injurious in heart failure (HF). (bmj.com)
- Patients with heart failure (HF) often present with central sleep apnea syndrome (CSA) and Cheyne-Stokes respiration, which is associated with increased mortality (1,2) . (onlinejacc.org)
- The goal of the study was to compare this new therapeutic option (SOMNOvent CR) with the established method of continuous positive airway pressure (CPAP) in patients with combination of obstructive sleep-apnea syndrome and Cheyne-Stokes-respiration with underlying heart disease. (clinicaltrials.gov)
Taber's Medical Dictionary1
- Cheyne-Stokes respiration is a sample topic from the Taber's Medical Dictionary . (unboundmedicine.com)
- The pathophysiology of Cheyne-Stokes breathing can be summarized as apnea leading to increased CO2 which causes excessive compensatory hyperventilation, in turn causing decreased CO2 which causes apnea, restarting the cycle. (wikipedia.org)
- As the authors note, Cheyne-Stokes respiration is characterized by periodic breathing in which apneas or hypopneas alternate with hyperventilation, occurring in a crescendo-decrescendo pattern of tidal volume (1). (annals.org)
- Cheyne-Stokes respiration is a type of breathing disorder characterized by cyclical episodes of apnea and hyperventilation. (statpearls.com)
- Also, the relative duration of hyperventilation is more than apnea duration in Cheyne-Stokes respiration. (statpearls.com)
- A breathing pattern marked by a period of apnea lasting 10 to 60 sec, followed by gradually increasing depth and frequency of respirations (hyperventilation). (unboundmedicine.com)
- ASV treatment in HF patients with Cheyne-Stokes respirations leads to an increase in SV likely mediated by a decrease in cardiac afterload due to an increased vagal activity. (ersjournals.com)
- In patients with heart failure, male gender, older age, sedentary lifestyle, diagnosis of atrial fibrillation, increased ventricular filling pressure and more advanced cardiac remodeling are known to predispose to Cheyne-Stokes respiration. (statpearls.com)
- The system's monitoring technology and signal analysis software are so advanced that it can automatically detect and classify apneas or hypopneas, Cheyne-Stokes respiration , sighs, and coughs, and correlate these with cardiac or other parameters -- all outside of the laboratory or clinical setting. (freethesaurus.com)
- All values represent the average of two to five consecutive cardiac cycles for each phase of respiration. (xhbv.com)
- Cheyne-Stokes respiration, also known as periodic respiration, is an abnormal pattern of breathing. (medicalnewstoday.com)
- Thus Cheyne-Stokes respiration can be maintained over periods of many minutes or hours with a repetitive pattern of apneas and hyperpneas. (wikipedia.org)
- If a person who is sleeping has cheyne-stokes respiration, the apnea durations are ten seconds or larger, and if there are more than five such apneas per hour of sleep, then the person has central sleep apnea. (sleepdisordersguide.com)
- Cheyne-Stokes respiration is a specific form of periodic breathing (waxing and waning amplitude of flow or tidal volume) characterized by a crescendo-decrescendo pattern of respiration between central apneas or central hypopneas. (statpearls.com)
- Cheyne-Stokes respiration should be differentiated from other central sleep apneas like idiopathic central sleep apnea where in there is no waxing and the waning pattern of ventilation. (statpearls.com)
- Cheyne-Stokes Respiration (CSR): CSR is a breathing pattern characterized by cycles of crescendo-decrescendo changes in tidal volume followed by central sleep apneas. (endocrinologyadvisor.com)
- The effects of central sleep apnea in Cheyne-Stokes respiration on sleep-related symptoms and quality of life are not very well established. (diva-portal.org)
- Cheyne-Stokes respiration is commonly linked to heart failure or stroke. (medicalnewstoday.com)
- Cognitive impairment in heart failure with Cheyne-Stokes respiration. (biomedsearch.com)
- METHODS: Overnight oximetry was used (previously validated as a screening tool for Cheyne-Stokes respiration in heart failure). (biomedsearch.com)
- In an earlier study we showed that Cheyne-Stokes respiration was seen in 21% of patients with compensated heart failure, and that these episodes of disordered breathing were associated with blood oxygen desaturation and fragmentation of normal sleep architecture. (bmj.com)
- Is Cheyne-Stokes respiration friend or foe of heart failure? (bmj.com)
- Cheyne-Stokes respiration in patients with heart failure: ominous sign or innocent bystander? (smw.ch)
- Effects of continuous positive airway pressure on cardiovascular outcomes in heart failure patients with and without Cheyne-Stokes respiration. (ahajournals.org)
- INTRODUCTION: Cheyne-Stokes respiration (CSR) and central sleep apnea (CSA) are common in patients with heart failure and/or stroke. (le.ac.uk)
- Heart failure disrupts this cycle resulting in cheyne-stokes respiration. (sleepdisordersguide.com)
- The cheyne-stokes respiration can be treated by treating the heart failure. (sleepdisordersguide.com)
- Unlike obstructive sleep apnea (OSA) which can be the cause of heart failure, Cheyne-Stokes respiration is believed to be a result of heart failure. (statpearls.com)
- Cheyne-Stokes respiration is well-studied in patients with heart failure and stroke. (statpearls.com)
- This means that out of nearly 5.7 million patients of heart failure, two to three million patients are expected to have Cheyne-Stokes respiration. (statpearls.com)
- The incidence is reported to be more in patients with systolic heart failure compared to diastolic heart failure, and Cheyne-Stokes respiration is also more common in elderly patients. (statpearls.com)
- A high prevalence of nocturnal Cheyne-Stokes respiration (CSR) has been documented in patients with heart failure with normal left ventricular ejection fraction (HFNEF). (uni-bielefeld.de)
- Treatment of Cheyne-Stokes respiration-central sleep apnea in patients with heart failure. (uni-bielefeld.de)
- Please cite this paper as: Midgren B, Mared L, Franklin KA, Berg S, Erhardt L and Cline C. Cheyne-Stokes respiration is not related to quality of life or sleepiness in heart failure. (lu.se)
- Cheyne J. A case of apoplexy in which the fleshy part of the heart was converted into fat . (litfl.com)
- Stokes W. Fatty degeneration of the heart . (litfl.com)
- Adaptive pressure support servo-ventilation: a novel treatment for Cheyne-Stokes respiration in heart failure. (freethesaurus.com)
- In patients with underlying heart diseases like hypertensive heart disease, coronary heart disease or dilative cardiomyopathy obstructive sleep-apnea, central sleep-apnea and Cheyne-Stokes-respiration are common finding in polysomnography. (clinicaltrials.gov)
- With the SOMNOvent CR a new therapy-algorithm has been developed for the adaptive servo ventilation in patients with obstructive sleep apnea and Cheyne-Stokes-respiration with underlying heart disease. (clinicaltrials.gov)
- In patients with stable severe heart failure, Cheyne-Stokes respiration (CSR) has been described in 30 to 50% of patients. (sleepscience.org.br)
- Could 600 mg temazepam overdose stop the heart and respiration? (healthtap.com)
- Using the HRV signal, we aimed to obtain parameters for classifying patients with and without chronic heart failure (CHF), and with periodic breathing (PB), non-periodic breathing (nPB), and Cheyne-Stokes respiration (CSR) patterns. (ibecbarcelona.eu)
- Elderly patients often have altered breathing patterns, such as periodic breathing (PB) and Cheyne-Stokes respiration (CSR), which may coincide with chronic heart failure. (ibecbarcelona.eu)
- High altitude periodic breathing (PB) shares some common pathophysiologic aspects with sleep apnea, Cheyne-Stokes respiration and PB in heart failure patients. (ibecbarcelona.eu)
- Weak heart and respiration. (homeoint.org)
Periods of apnea1
- A pattern of breathing with varying depth of respiration and brief periods of apnea. (medindia.net)
- Perhaps because of his renown in the medical world, Stokes' name has become inextricably linked to John Cheyne in the definition of Cheyne-Stokes Respiration. (blogspot.com)
- With Reverso you can find the English translation, definition or synonym for harsh respiration and thousands of other words. (reverso.net)
- It consists of cycles of breathing, which become increasingly deeper, followed by periods where respiration becomes gradually shallower. (medicalnewstoday.com)
- Cheyne-Stokes respiration is an abnormal pattern of breathing characterized by progressively deeper, and sometimes faster, breathing followed by a gradual decrease that results in a temporary stop in breathing called an apnea. (wikipedia.org)
- Cheyne-Stokes respiration and periodic breathing are the two regions on a spectrum of severity of oscillatory tidal volume. (wikipedia.org)
- The distinction lies in what is observed at the trough of ventilation: Cheyne-Stokes respiration involves apnea (since apnea is a prominent feature in their original description) while periodic breathing involves hypopnea (abnormally small but not absent breaths). (wikipedia.org)
- Cheyne-stokes respiration has alternate periods of no breathing changing smoothly into periods of hyper breathing, which smoothly change back into no breathing. (sleepdisordersguide.com)
- Cheyne-stokes respirations are a pattern of breathing which is very irregular, and not surprisingly, is sometimes referred to as 'agonal breathing. (verywellhealth.com)
- During Cheyne-Stokes, breathing can be very deep and rapid (hyperpnea), followed by periods of slow shallow breaths, or interrupted by episodes of apnea, in which an individual stops breathing altogether for a period of time. (verywellhealth.com)
- Though Cheyne Stokes breathing may appear erratic, it often occurs in cycles lasting between 30 seconds and two minutes. (verywellhealth.com)
- Cheyne-Stokes breathing is commonly seen when people are in the dying process from any illness including cancer. (verywellhealth.com)
- Recent thought has been that Cheyne-Stokes breathing may be a way in which the body compensates in some way, rather than a problem in and of itself. (verywellhealth.com)
- Breathing patterns are graded, because Cheyne-Stokes respiration and irregular breathing can represent bihemispheric or lower brainstem dysfunction. (freethesaurus.com)
- Cheyne-Stokes Respiration (CSR) is an abnormal type of breathing characterized by alternating periods of shallow and deep breathing. (fandom.com)
- ResMed's new Cheyne-Stokes respiration (CSR) detection feature helps you identify patients who are using fixed or auto-adjusting pressure devices, but who may present with CSR breathing patterns. (resmed.com)
- Repeated breathing pattern characterized by fluctuation in the depth of respiration, first deeply, then shallow, then not at all. (studystack.com)
- Typical breathing pattern with Cheyne-Stokes respiration with hyperpnoeic and apnoeic sequences in sleep stage 2. (bmj.com)
- Cheyne-Stokes respiration (CSR) is commonly used as a synonym for periodic breathing, but some authors distinguish between the two. (bmj.com)
- 13-16 Sleep-disordered breathing at altitude and Cheyne-Stokes respiration (CSR) in particular add to the hypoxic burden. (wiley.com)
- The proposed mechanism behind this was either nocturnal hypoxaemia from apnoeas, or repeated arousal from sleep during the hyperpnoeic phase of Cheyne-Stokes respiration. (bmj.com)
Pattern of respiration1
- However, this pattern of respiration was not apparent in the figures that were presented. (annals.org)
- Marais OAS, McMichael J (1937) Theophylline-ethylenediamine in Cheyne-Stokes respiration. (springer.com)
- The true prevalence of Cheyne-Stokes respiration in the general population is not known and is considered to be rare. (statpearls.com)
- called also cell respiration . (thefreedictionary.com)
- The ventilation length in patients with Cheyne-Stokes respiration is more than 40 seconds compared to less than 40 seconds in central sleep apnea. (statpearls.com)
- Nursing Central , nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/767599/all/Cheyne_Stokes_respiration. (unboundmedicine.com)
- My observation is that CSR is a very persistent pattern and has a very characteristic pattern that is a very gradual waxing and waning of respiration, punctuated with a central apnea. (apneaboard.com)
- The exact underlying pathomechanism of central sleep apnea with Cheyne-Stokes respiration (CSA-CSR) is still unclear. (nih.gov)
- Earlier studies proved the adaptive servo ventilation to be an effective therapy for patients with central sleep-apnea and Cheyne-Stokes-respiration respectively. (clinicaltrials.gov)
- Hiperventilacão e baixos níveis de CO2 arterial (PaCO2), que quando abaixo do limiar de apnéia desencadeiam apnéia central são os mecanismos fisiopatológicos chave na gênese da respiração de Cheyne-Stokes . (bvsalud.org)
- While Cheyne-Stokes respiration usually occurs during slee, it may also happen during waking hours. (medicalnewstoday.com)
- Cheyne wrote a number of books, including Essays of Diseases of Children in 1801. (wikipedia.org)
Dublin Hospital Reports1
- Twenty-eight years after Cheyne's work, Stokes recorded another example of the respiration phenomenon for publication in the 'Dublin Hospital Reports' and quoted Cheyne, although he apparently added no new details. (blogspot.com)
- Respiration in which the chest cavity expands by raising the ribs. (tabers.com)
- 5minute , www.unboundmedicine.com/5minute/view/Diagnosaurus/114604/all/Cheyne_Stokes_respiration. (unboundmedicine.com)
- Finally, in a recent study, we aimed to evaluate acute effects of adaptive servo ventilation (ASV) on Cheyne-Stokes respiration (CSR) and neurohormones in the patients with HE and showed that one night ASV treatment improves CSR, partial pressure of oxygen in arterial blood, and oxygen saturation and provides significant reductions in plasma catecholamines and NT-proBNP levels in the patients with HF and CSR (6). (freethesaurus.com)
- Up to 20% of patients with stroke can exhibit Cheyne-Stokes respiration. (statpearls.com)