Click Chemistry: Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.Chemistry, Clinical: The specialty of ANALYTIC CHEMISTRY applied to assays of physiologically important substances found in blood, urine, tissues, and other biological fluids for the purpose of aiding the physician in making a diagnosis or following therapy.Chemistry, Organic: The study of the structure, preparation, properties, and reactions of carbon compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Clinical Chemistry Tests: Laboratory tests demonstrating the presence of physiologically significant substances in the blood, urine, tissue, and body fluids with application to the diagnosis or therapy of disease.Chemistry: A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.Chemistry, Analytic: The branch of chemistry dealing with detection (qualitative) and determination (quantitative) of substances. (Grant & Hackh's Chemical Dictionary, 5th ed)Combinatorial Chemistry Techniques: A technology, in which sets of reactions for solution or solid-phase synthesis, is used to create molecular libraries for analysis of compounds on a large scale.Blood Chemical Analysis: An examination of chemicals in the blood.Alkynes: Hydrocarbons with at least one triple bond in the linear portion, of the general formula Cn-H2n-2.Chemistry, Pharmaceutical: Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.Nobel PrizeMolecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Chemistry Techniques, Synthetic: Methods used for the chemical synthesis of compounds. Included under this heading are laboratory methods used to synthesize a variety of chemicals and drugs.Green Chemistry Technology: Pollution prevention through the design of effective chemical products that have low or no toxicity and use of chemical processes that reduce or eliminate the use and generation of hazardous substances.Organic Chemistry Phenomena: The conformation, properties, reaction processes, and the properties of the reactions of carbon compounds.Chemistry Techniques, Analytical: Methodologies used for the isolation, identification, detection, and quantitation of chemical substances.Chemistry, Physical: The study of CHEMICAL PHENOMENA and processes in terms of the underlying PHYSICAL PHENOMENA and processes.Evolution, Chemical: Chemical and physical transformation of the biogenic elements from their nucleosynthesis in stars to their incorporation and subsequent modification in planetary bodies and terrestrial biochemistry. It includes the mechanism of incorporation of biogenic elements into complex molecules and molecular systems, leading up to the origin of life.Surface Properties: Characteristics or attributes of the outer boundaries of objects, including molecules.Cyclization: Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Azides: Organic or inorganic compounds that contain the -N3 group.Biochemistry: The study of the composition, chemical structures, and chemical reactions of living things.Models, Chemical: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).Catalysis: The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.Cosmic Dust: Finely divided solid matter with particle sizes smaller than a micrometeorite, thus with diameters much smaller than a millimeter, moving in interplanetary space. (NASA Thesaurus, 1994)Drug Design: The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of molecular properties such as activity of functional groups, molecular geometry, and electronic structure, and also on information cataloged on analogous molecules. Drug design is generally computer-assisted molecular modeling and does not include pharmacokinetics, dosage analysis, or drug administration analysis.Extraterrestrial Environment: The environment outside the earth or its atmosphere. The environment may refer to a closed cabin (such as a space shuttle or space station) or to space itself, the moon, or other planets.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Biogenesis: The origin of life. It includes studies of the potential basis for life in organic compounds but excludes studies of the development of altered forms of life through mutation and natural selection, which is BIOLOGICAL EVOLUTION.Atmosphere: The gaseous envelope surrounding a planet or similar body. (From Random House Unabridged Dictionary, 2d ed)Organic Chemistry Processes: The reactions, changes in structure and composition, the properties of the reactions of carbon compounds, and the associated energy changes.Organic Chemicals: A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.Polymers: Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).Astronomy: The science concerned with celestial bodies and the observation and interpretation of the radiation received in the vicinity of the earth from the component parts of the universe (McGraw Hill Dictionary of Scientific and Technical Terms, 5th ed)Quantum Theory: The theory that the radiation and absorption of energy take place in definite quantities called quanta (E) which vary in size and are defined by the equation E=hv in which h is Planck's constant and v is the frequency of the radiation.Water: A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Molecular Conformation: The characteristic three-dimensional shape of a molecule.Photoelectron Spectroscopy: The study of the energy of electrons ejected from matter by the photoelectric effect, i.e., as a direct result of absorption of energy from electromagnetic radiation. As the energies of the electrons are characteristic of a specific element, the measurement of the energy of these electrons is a technique used to determine the chemical composition of surfaces.Copper: A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.Adsorption: The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.History, 19th Century: Time period from 1801 through 1900 of the common era.Carbonates: Salts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed)Nanotechnology: The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.Radiochemistry: The study of the chemical and physical phenomena of radioactive substances.Drug Discovery: The process of finding chemicals for potential therapeutic use.Indicators and Reagents: Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)Magnetic Resonance Spectroscopy: Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).Enzymes: Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.Gases: The vapor state of matter; nonelastic fluids in which the molecules are in free movement and their mean positions far apart. Gases tend to expand indefinitely, to diffuse and mix readily with other gases, to have definite relations of volume, temperature, and pressure, and to condense or liquefy at low temperatures or under sufficient pressure. (Grant & Hackh's Chemical Dictionary, 5th ed)Biological Products: Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.Coordination Complexes: Neutral or negatively charged ligands bonded to metal cations or neutral atoms. The number of ligand atoms to which the metal center is directly bonded is the metal cation's coordination number, and this number is always greater than the regular valence or oxidation number of the metal. A coordination complex can be negative, neutral, or positively charged.Quality Control: A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)Organometallic Compounds: A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Structure-Activity Relationship: The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.Exobiology: The interdisciplinary science that studies evolutionary biology, including the origin and evolution of the major elements required for life, their processing in the interstellar medium and in protostellar systems. This field also includes the study of chemical evolution and the subsequent interactions between evolving biota and planetary evolution as well as the field of biology that deals with the study of extraterrestrial life.Photochemical Processes: Chemical reactions effected by light.Nanoparticles: Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.History, 18th Century: Time period from 1701 through 1800 of the common era.Kinetics: The rate dynamics in chemical or physical systems.Autoanalysis: Method of analyzing chemicals using automation.Mass Spectrometry: An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.Sulfhydryl Compounds: Compounds containing the -SH radical.Biology: One of the BIOLOGICAL SCIENCE DISCIPLINES concerned with the origin, structure, development, growth, function, genetics, and reproduction of animals, plants, and microorganisms.Solar System: The group of celestial bodies, including the EARTH, orbiting around and gravitationally bound by the sun. It includes eight planets, one minor planet, and 34 natural satellites, more than 1,000 observed comets, and thousands of lesser bodies known as MINOR PLANETS (asteroids) and METEOROIDS. (From Academic American Encyclopedia, 1983)Hydrocarbons, Cyclic: Organic compounds composed exclusively of carbon and hydrogen forming a closed ring that may be either alicyclic or aromatic.Small Molecule Libraries: Large collections of small molecules (molecular weight about 600 or less), of similar or diverse nature which are used for high-throughput screening analysis of the gene function, protein interaction, cellular processing, biochemical pathways, or other chemical interactions.Hematologic Tests: Tests used in the analysis of the hemic system.Amines: A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)Metals: Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)Fullerenes: A polyhedral CARBON structure composed of around 60-80 carbon atoms in pentagon and hexagon configuration. They are named after Buckminster Fuller because of structural resemblance to geodesic domes. Fullerenes can be made in high temperature such as arc discharge in an inert atmosphere.Ligands: A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)Silanes: Compounds similar to hydrocarbons in which a tetravalent silicon atom replaces the carbon atom. They are very reactive, ignite in air, and form useful derivatives.Nanostructures: Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES.Crystallography, X-Ray: The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)History, 20th Century: Time period from 1901 through 2000 of the common era.Chemical Phenomena: The composition, conformation, and properties of atoms and molecules, and their reaction and interaction processes.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Ecotoxicology: The study of ENVIRONMENTAL POLLUTION and the toxic effects of ENVIRONMENTAL POLLUTANTS on the ECOSYSTEM. The term was coined by Truhaut in 1969.Dendrimers: Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS.Carbon: A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.Peptides: Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.Chemical Processes: The reactions and interactions of atoms and molecules, the changes in their structure and composition, and associated energy changes.Biosensing Techniques: Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal.Microscopy, Scanning Tunneling: A type of scanning probe microscopy in which a very sharp conducting needle is swept just a few angstroms above the surface of a sample. The tiny tunneling current that flows between the sample and the needle tip is measured, and from this are produced three-dimensional topographs. Due to the poor electron conductivity of most biological samples, thin metal coatings are deposited on the sample.Electrons: Stable elementary particles having the smallest known negative charge, present in all elements; also called negatrons. Positively charged electrons are called positrons. The numbers, energies and arrangement of electrons around atomic nuclei determine the chemical identities of elements. Beams of electrons are called CATHODE RAYS.Thermodynamics: A rigorously mathematical analysis of energy relationships (heat, work, temperature, and equilibrium). It describes systems whose states are determined by thermal parameters, such as temperature, in addition to mechanical and electromagnetic parameters. (From Hawley's Condensed Chemical Dictionary, 12th ed)Metal Nanoparticles: Nanoparticles produced from metals whose uses include biosensors, optics, and catalysts. In biomedical applications the particles frequently involve the noble metals, especially gold and silver.Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.PhotochemistryFluorescent Dyes: Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Oxygen: An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.Electrochemistry: The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.Particle Size: Relating to the size of solids.Alkenes: Unsaturated hydrocarbons of the type Cn-H2n, indicated by the suffix -ene. (Grant & Hackh's Chemical Dictionary, 5th ed, p408)Sulfur Compounds: Inorganic or organic compounds that contain sulfur as an integral part of the molecule.Elements: Substances that comprise all matter. Each element is made up of atoms that are identical in number of electrons and protons and in nuclear charge, but may differ in mass or number of neutrons.Molecular Probes: A group of atoms or molecules attached to other molecules or cellular structures and used in studying the properties of these molecules and structures. Radioactive DNA or RNA sequences are used in MOLECULAR GENETICS to detect the presence of a complementary sequence by NUCLEIC ACID HYBRIDIZATION.Biomimetics: An interdisciplinary field in materials science, ENGINEERING, and BIOLOGY, studying the use of biological principles for synthesis or fabrication of BIOMIMETIC MATERIALS.Iron: A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.Spectrum Analysis: The measurement of the amplitude of the components of a complex waveform throughout the frequency range of the waveform. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Cyclooctanes: A group of compounds with an 8-carbon ring. They may be saturated or unsaturated.Wettability: The quality or state of being wettable or the degree to which something can be wet. This is also the ability of any solid surface to be wetted when in contact with a liquid whose surface tension is reduced so that the liquid spreads over the surface of the solid.Meteoroids: Any solid objects moving in interplanetary space that are smaller than a planet or asteroid but larger than a molecule. Meteorites are any meteoroid that has fallen to a planetary surface. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Agrochemicals: Chemicals used in agriculture. These include pesticides, fumigants, fertilizers, plant hormones, steroids, antibiotics, mycotoxins, etc.Volcanic Eruptions: The ash, dust, gases, and lava released by volcanic explosion. The gases are volatile matter composed principally of about 90% water vapor, and carbon dioxide, sulfur dioxide, hydrogen, carbon monoxide, and nitrogen. The ash or dust is pyroclastic ejecta and lava is molten extrusive material consisting mainly of magnesium silicate. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Ions: An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Biological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Pharmaceutical Preparations: Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.Physicochemical Phenomena: The physical phenomena describing the structure and properties of atoms and molecules, and their reaction and interaction processes.Nanomedicine: The branch of medicine concerned with the application of NANOTECHNOLOGY to the prevention and treatment of disease. It involves the monitoring, repair, construction, and control of human biological systems at the molecular level, using engineered nanodevices and NANOSTRUCTURES. (From Freitas Jr., Nanomedicine, vol 1, 1999).Laboratories: Facilities equipped to carry out investigative procedures.Cycloaddition Reaction: Synthetic organic reactions that use reactions between unsaturated molecules to form cyclical products.Cross-Linking Reagents: Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Physics: The study of those aspects of energy and matter in terms of elementary principles and laws. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Environmental Pollution: Contamination of the air, bodies of water, or land with substances that are harmful to human health and the environment.History, 21st Century: Time period from 2001 through 2100 of the common era.Clinical Laboratory Techniques: Techniques used to carry out clinical investigative procedures in the diagnosis and therapy of disease.Solid-Phase Synthesis Techniques: Techniques used to synthesize chemicals using molecular substrates that are bound to a solid surface. Typically a series of reactions are conducted on the bound substrate that results in either the covalent attachment of specific moieties or the modification of existing function groups. These techniques offer an advantage to those involving solution reactions in that the substrate compound does not have to be isolated and purified between the reaction steps.Hydrocarbons, FluorinatedBenzene DerivativesChromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Heterocyclic Compounds: Ring compounds having atoms other than carbon in their nuclei. (Grant & Hackh's Chemical Dictionary, 5th ed)Silicon: A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Glass: Hard, amorphous, brittle, inorganic, usually transparent, polymerous silicate of basic oxides, usually potassium or sodium. It is used in the form of hard sheets, vessels, tubing, fibers, ceramics, beads, etc.Polyethylene Glycols: Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.Laboratories, Hospital: Hospital facilities equipped to carry out investigative procedures.Lightning: An abrupt high-current electric discharge that occurs in the ATMOSPHERE and that has a path length ranging from hundreds of feet to tens of miles. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Silicon Dioxide: Transparent, tasteless crystals found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite. The compound is insoluble in water or acids except hydrofluoric acid.Halogens: A family of nonmetallic, generally electronegative, elements that form group 17 (formerly group VIIa) of the periodic table.Evolution, Planetary: Creation and development of bodies within solar systems, includes study of early planetary geology.Drug Delivery Systems: Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.Oligonucleotides: Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed)Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.Aldehydes: Organic compounds containing a carbonyl group in the form -CHO.Solutions: The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)Blood Urea Nitrogen: The urea concentration of the blood stated in terms of nitrogen content. Serum (plasma) urea nitrogen is approximately 12% higher than blood urea nitrogen concentration because of the greater protein content of red blood cells. Increases in blood or serum urea nitrogen are referred to as azotemia and may have prerenal, renal, or postrenal causes. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)Chemistry, Inorganic: A field of chemistry which pertains to chemical compounds or ions that do not contain the element carbon (with the exception of carbon dioxide and compounds containing a carbonate radical, e.g., calcium carbonate).Acid Rain: Acidic water usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water.Nucleic Acids: High molecular weight polymers containing a mixture of purine and pyrimidine nucleotides chained together by ribose or deoxyribose linkages.Catalytic Domain: The region of an enzyme that interacts with its substrate to cause the enzymatic reaction.Spectrum Analysis, Raman: Analysis of the intensity of Raman scattering of monochromatic light as a function of frequency of the scattered light.Calcium Carbonate: Carbonic acid calcium salt (CaCO3). An odorless, tasteless powder or crystal that occurs in nature. It is used therapeutically as a phosphate buffer in hemodialysis patients and as a calcium supplement.Brain Chemistry: Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.Hydrogen Bonding: A low-energy attractive force between hydrogen and another element. It plays a major role in determining the properties of water, proteins, and other compounds.Nucleic Acid Probes: Nucleic acid which complements a specific mRNA or DNA molecule, or fragment thereof; used for hybridization studies in order to identify microorganisms and for genetic studies.IminesNitrogen Oxides: Inorganic oxides that contain nitrogen.Groundwater: Liquid water present beneath the surface of the earth.Protons: Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion.Hydrogen: The first chemical element in the periodic table. It has the atomic symbol H, atomic number 1, and atomic weight [1.00784; 1.00811]. It exists, under normal conditions, as a colorless, odorless, tasteless, diatomic gas. Hydrogen ions are PROTONS. Besides the common H1 isotope, hydrogen exists as the stable isotope DEUTERIUM and the unstable, radioactive isotope TRITIUM.Saturn: The sixth planet in order from the sun. It is one of the five outer planets of the solar system. Its twelve natural satellites include Phoebe and Titan.Microscopy, Atomic Force: A type of scanning probe microscopy in which a probe systematically rides across the surface of a sample being scanned in a raster pattern. The vertical position is recorded as a spring attached to the probe rises and falls in response to peaks and valleys on the surface. These deflections produce a topographic map of the sample.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Bromine: A halogen with the atomic symbol Br, atomic number 36, and atomic weight 79.904. It is a volatile reddish-brown liquid that gives off suffocating vapors, is corrosive to the skin, and may cause severe gastroenteritis if ingested.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Anions: Negatively charged atoms, radicals or groups of atoms which travel to the anode or positive pole during electrolysis.Microfluidic Analytical Techniques: Methods utilizing the principles of MICROFLUIDICS for sample handling, reagent mixing, and separation and detection of specific components in fluids.Free Radicals: Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.Interdisciplinary Studies: Programs of study which span the traditional boundaries of academic scholarship.Ferric Compounds: Inorganic or organic compounds containing trivalent iron.Earth (Planet): Planet that is the third in order from the sun. It is one of the four inner or terrestrial planets of the SOLAR SYSTEM.Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)Eagles: Large members of the FALCONIFORMES order of birds, family Accipitridae, most especially the genera Aquila, Haliaeetus, Harpia, and Circaetus. They are characterized by their powerful talons, which carry long, curved, pointed claws and by their opposable hindtoe.Microfluidics: The study of fluid channels and chambers of tiny dimensions of tens to hundreds of micrometers and volumes of nanoliters or picoliters. This is of interest in biological MICROCIRCULATION and used in MICROCHEMISTRY and INVESTIGATIVE TECHNIQUES.KetonesCations: Positively charged atoms, radicals or groups of atoms which travel to the cathode or negative pole during electrolysis.Hydrophobic and Hydrophilic Interactions: The thermodynamic interaction between a substance and WATER.Bilirubin: A bile pigment that is a degradation product of HEME.Computer Simulation: Computer-based representation of physical systems and phenomena such as chemical processes.Substrate Specificity: A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.Spectroscopy, Fourier Transform Infrared: A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.Biochemical Phenomena: The chemical processes, enzymatic activities, and pathways of living things and related temporal, dimensional, qualitative, and quantitative concepts.Seawater: The salinated water of OCEANS AND SEAS that provides habitat for marine organisms.Macrocyclic Compounds: Cyclic compounds with a ring size of approximately 1-4 dozen atoms.Natural Science Disciplines: The sciences dealing with processes observable in nature.Isotope Labeling: Techniques for labeling a substance with a stable or radioactive isotope. It is not used for articles involving labeled substances unless the methods of labeling are substantively discussed. Tracers that may be labeled include chemical substances, cells, or microorganisms.Carboxylic Acids: Organic compounds containing the carboxy group (-COOH). This group of compounds includes amino acids and fatty acids. Carboxylic acids can be saturated, unsaturated, or aromatic.Lanthanoid Series Elements: Elements of the lanthanoid series including atomic number 57 (LANTHANUM) through atomic number 71 (LUTETIUM).Halogenation: Covalent attachment of HALOGENS to other compounds.Phosphorus: A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.Polystyrenes: Polymerized forms of styrene used as a biocompatible material, especially in dentistry. They are thermoplastic and are used as insulators, for injection molding and casting, as sheets, plates, rods, rigid forms and beads.HydrocarbonsAlpha Particles: Positively charged particles composed of two protons and two NEUTRONS, i.e. equivalent to HELIUM nuclei, which are emitted during disintegration of heavy ISOTOPES. Alpha rays have very strong ionizing power, but weak penetrability.Organophosphorus Compounds: Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.Transition Elements: Elements with partially filled d orbitals. They constitute groups 3-12 of the periodic table of elements.Biocatalysis: The facilitation of biochemical reactions with the aid of naturally occurring catalysts such as ENZYMES.Hydroxyl Radical: The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.Alkylation: The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group.Graphite: An allotropic form of carbon that is used in pencils, as a lubricant, and in matches and explosives. It is obtained by mining and its dust can cause lung irritation.

Within- and between-subject variation in commonly measured anthropometric and biochemical variables. (1/527)

BACKGROUND: The biological variation of some commonly assessed metabolic variables in healthy subjects has not been studied extensively. The aim of the study was to assess, in 12 healthy subjects (6 male and 6 female; mean (SD) age; 22.7 (1.5) years) following an overnight fast, the day-to-day variation of body fat (impedance method), triglycerides, nonesterified fatty acid (NEFAs), glycerol, 3-hydroxybutyrate (3-OHB), lactate, glucose, insulin (RIA), C-peptide, and glucagon on 12 consecutive days. METHODS: Between- and within-subject coefficients of variation (CVG and CVW) were estimated using a random effects analysis of variance, and assay variation was subtracted to give the coefficient of within-subject biological variation (CVI). Individuality indices were calculated as CVW/CVG. RESULTS: The overall means, CVI, and individuality indices were as follows: for body fat, 24.2%, 10%, and 0.3; for triglycerides, 0.61 mmol/L, 21%, and 1.1; for NEFAs, 376 micromol/L, 45%, and 1.4; for glycerol, 48 micromol/L, 36%, and 0.8; for 3-OHB, 43 micromol/L, 61%, and 1.5; for lactate, 0.88 mmol/L, 31%, and 1.1; for glucose, 4.9 mmol/L, 4.8%, and 0.7; for insulin, 52 pmol/L, 26%, and 1.0; for C-peptide, 0.39 nmol/L, 24%, and 0.9; and for glucagon, 53 ng/L, 19%, and 0.8. CONCLUSIONS: The data presented here are necessary for the evaluation of several important metabolic variables in individual and group studies. The biological variation of some metabolites makes it difficult to characterize the status of healthy subjects with a single measurement.  (+info)

Affinity chromatography: a review of clinical applications. (2/527)

Affinity chromatography is a type of liquid chromatography that makes use of biological-like interactions for the separation and specific analysis of sample components. This review describes the basic principles of affinity chromatography and examines its use in the testing of clinical samples, with an emphasis on HPLC-based methods. Some traditional applications of this approach include the use of boronate, lectin, protein A or protein G, and immunoaffinity supports for the direct quantification of solutes. Newer techniques that use antibody-based columns for on- or off-line sample extraction are examined in detail, as are methods that use affinity chromatography in combination with other analytical methods, such as reversed-phase liquid chromatography, gas chromatography, and capillary electrophoresis. Indirect analyte detection methods are also described in which immunoaffinity chromatography is used to perform flow-based immunoassays. Other applications that are reviewed include affinity-based chiral separations and the use of affinity chromatography for the study of drug or hormone interactions with binding proteins. Some areas of possible future developments are then considered, such as tandem affinity methods and the use of synthetic dyes, immobilized metal ions, molecular imprints, or aptamers as affinity ligands for clinical analytes.  (+info)

History of clinical chemistry in a children's hospital (1914-1964). (3/527)

The historical development of a charitable children's hospital and the evolution of its clinical laboratory are presented. With the appearance of practical quantitative blood chemistry tests in the period between the two World Wars, applications to pediatrics were hampered by the need for ultramicro procedures then unavailable and for improved skin-puncture blood sampling. World War II brought economic demands that forced the hospital to privatize its beds and to charge fee-for-services. In turn, this brought added income, allowing the hiring or subsidizing of a professional staff, including the clinical chemist. The development of ultramicro blood chemistry followed, along with improved skin-puncture technology.  (+info)

A golden age of clinical chemistry: 1948-1960. (4/527)

This segment of history aims to inform the new, and remind the not-so-new, members of the profession about the relatively recent period that initiated the dominant role played by technological innovation in the modern investigation of disease. The 12 years from 1948 to 1960 were notable for introduction of the Vacutainer tube, electrophoresis, radioimmunoassay, and the AutoAnalyzer. Also appearing during this interval were new organizations, publications, programs, and services that established a firm foundation for the professional status of clinical chemists. It was a golden age.  (+info)

A reference method laboratory network for cholesterol: a model for standardization and improvement of clinical laboratory measurements. (5/527)

BACKGROUND: Accurate and precise measurement of blood cholesterol plays a central role in the National Cholesterol Education Program's strategy to reduce the morbidity and mortality attributable to coronary heart disease. Matrix effects hamper the ability of manufacturers to adequately calibrate and validate traceability to the National Reference System for Cholesterol (NRS/CHOL). CDC created the Cholesterol Reference Method Laboratory Network (CRMLN) to improve cholesterol measurement by assisting manufacturers of in vitro diagnostic products with validation of the traceability of their assays to the NRS/CHOL. METHODS: CRMLN laboratories established the CDC cholesterol reference method (modification of the Abell-Levy-Brodie-Kendall chemical method) and are standardized using CDC frozen serum reference materials. CRMLN laboratories use common quality-control materials and participate in monthly external performance evaluations conducted by CDC. The CRMLN performance criteria require member laboratories to agree with CDC within +/-1.0% and maintain a CV < or =2.0%. RESULTS: From 1995 to 200 the CRMLN laboratories met the accuracy criterion 97% of the time and the precision criterion 99% of the time. During this time period, the CRMLN maintained an average bias to CDC of 0.01% and an average collective CV of 0.33%. CONCLUSIONS: CDC established the CRMLN as the first international reference method laboratory network. The CRMLN assists manufacturers in the validation of the calibration of their diagnostic products so that clinical laboratories can measure blood cholesterol more reliably. The CRMLN can serve as a model for other clinical analytes where traceability to a hierarchy of methods is needed and matrix effects of the field methods with processed calibrators or reference materials are present.  (+info)

Establishment and characteristics of four sub-strains of F344 rats reared on various low protein and low energy diets. (6/527)

Four sub-strains, reared by sib-mating and having for their origin the F344/DuCrj strain of rats, were established by feeding with different levels of low protein and low energy diets, and their characteristics investigated. The amounts of crude protein (CP) and digestible energy (DE) in the four diets were 17.6%-3.0 kcal, 10.5%-2.5 kcal, 8.4%-2.0 kcal, and 10.5%-2.5 kcal, respectively, and the four sub-strains established here were provisionally designated as F344/Tig1, F344/Tig2, F344/Tig3 and F344/Tig4, respectively. Intakes of nitrogen-corrected metabolizable energy (MEn) did not differ, and a large intake of digestible crude protein (DCP) was observed in F344/Tig1 rats. The body weight of rats provided with lower-nutrient diets showed a tendency to decrease until the F2 generation, but no change among the generations was seen subsequently, and the same compiled differences in protein content were maintained. Similar transitions were observed in the lifetime rearing test. Though F344/Tig3 rats, which were reared on minimum nutrients, showed a tendency to delayed puberty, we were easily able to breed four pairs in every generation using procedures similar to those used for other strains of rats. There were no differences among the F344/Tig1 to -3 strains of rats in body length, digestive tract length, or organ weight per body weight, and all the rats had a normal range of biochemical values. But the F344/Tig4 showed a high glutamic-oxaloacetic transaminase (GOT), and a tendency to decreased liver function and a shorter lifespan. These sub-strains of F344 rats clarified differences in fatty acid compositions, such as docosahexaenoic acid (DHA) in serum, liver and the brain. The rats were intended to be useful animal models for the study of nutritional environments and their influence on the memory and learning.  (+info)

Reference intervals for glucose, beta-cell polypeptides, and counterregulatory factors during prolonged fasting. (7/527)

To establish reference intervals for the pancreatic beta-cell response and the counterregulatory hormone response to prolonged fasting, we studied 33 healthy subjects (16 males, 17 females) during a 72-h fast. Glucose, insulin, C-peptide, and proinsulin levels decreased (P < 0.001), and the levels of counterregulatory factors increased during the fast [P < 0.05; glucagon and free fatty acids (FFA) with a linear increase and epinephrine, norepinephrine, and cortisol with a clear underlying circadian rhythm]. Growth hormone secretion increased from the first to third day of fasting (P < 0.05) but actually decreased from the second to third day of fasting (P = 0.03). Males had higher glucose and glucagon levels and lower FFA levels during the fast (P < 0.05), whereas no effect of gender on beta-cell polypeptides was observed. A high body mass index resulted in higher insulin and C-peptide levels during the fast (P < 0.05). In conclusion, we have provided reference intervals for glucoregulatory factors during a 72-h fast. We observed a diminished beta-cell response concomitant with an increased secretion of counterregulatory hormones. These results should be of clinical and scientific value in the investigation of hypoglycemic disorders.  (+info)

Toxicology and carcinogenesis studies of p,p'-dichlorodiphenyl sulfone in rats and mice. (8/527)

p,p'-Dichlorodiphenyl sulfone (DDS) is used as a starting material in the production of polysulfones and polyethersufones, a family of thermoplastics. DDS was studied because of its high production volume and use. In toxicology studies, 10 Fischer 344 rats and 10 B6C3F1 mice/sex/group were fed diets containing 0, 30, 100, 300, 1,000 or 3,000 ppm DDS for 14 weeks. All animals survived until the end of the studies. Mean body weights of groups exposed to 300 ppm or greater were significantly decreased. Liver and kidney in rats and liver in mice were the major target organs of DDS toxicity. Dose-related increases in liver weights and incidences of centrilobular hepatocyte hypertrophy were observed in DDS-exposed groups. Nephropathy was seen in male and female rats only at and above 300 ppm. Neurotoxicity evaluations were negative in DDS-treated animals. Clinical chemistry and hematology parameters were minimally affected. In the 2-year toxicity and carcinogenicity studies, 50 rats and 50 mice/sex/group were fed diets containing 0, 10 (male rats), 30, 100, or 300 ppm DDS for 104 to 105 weeks. Survival of exposed groups was not affected. There were no clinical signs of toxicity related to DDS exposure. Final mean body weights were 2-17% lower in DDS-treated groups. Liver was the only target organ of DDS-induced toxicity. The incidence of centrilobular hepatocyte hypertrophy in mice and rats, and the incidence of bile duct hyperplasia and centrilobular degeneration in female rats was significantly greater than in controls. A no-observed-adverse-effect level (NOAEL) of 30 ppm DDS in the diet (1.5 mg/kg body weight) was established for rats. DDS was not carcinogenic in these studies.  (+info)

3,816 Clinical Laboratory Scientist jobs available on Indeed.com. Clinical Laboratory Scientist, Scientist, Clinical Laboratory Scientist II and more!
Todays top 242 Clinical Laboratory Scientist jobs in New York, NY. See salaries, check reviews and get hired. New Clinical Laboratory Scientist jobs added daily.
The analytical goals inferred desirable by a group of clinicians for the imprecisions of a wide range of analytes have been studied by survey. The goals required have not in general become more stringent in the past decade and are not as demanding as those promulgated by laboratory professionals. Clinical biochemistry laboratories can now attain analytical imprecisions which satisfy the general demands of clinicians except for analyses of calcium and of low levels of glucose. The lack of published data on analytical goals does not allow wide comparison of criteria for performance standards with the results of this study.. ...
2ndInternational conference on Clinical Chemistry and Laboratory Medicine. September 28-29, 2017 Atlanta, Georgia, USA.. Theme:. An Insight into advancement of medicine by extending the frontiers of clinical chemistry and laboratory medicine. The Conference organized by the Conference Series was an outstanding American event devoted to the Pharmaceuticals Practice of Chemistry and research findings, and it gave participants a platform to discussing the clinical practice, Clinical trials, Laboratory medicines and consequences and challenges in Clinical Chemistry &Laboratory Medicine industry and to discover novel opportunities, meet colleagues, and broaden their knowledge. Conference was organized very well. It broadly covered all disciplines of Clinical Chemistry &Laboratory Medicine from fundamental research to applications.Everyone interested in the future of innovating new critical analysis data - clinical analytical techniques and majorly in Clinical Chemistry &Laboratory Medicine is ...
HTF Market Intelligence released a new research report of 166 pages on title Clinical Chemistry Analyzers - Medical Devices Pipeline Assessment, 2016 with
EKF Diagnostics, the global in vitro diagnostics company, launched the Altair™ 240 clinical chemistry analyzer to the European market at Medica 2015, Düsseldorf, 16-19th November.
Atellica Solution immunoassay and clinical chemistry analyzers with revolutionary sample management and intelligent scheduling software
SAN DIEGO, Jan. 22, 2018 (GLOBE NEWSWIRE) -- Diazyme Laboratories, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted 510(K) clearance to market its EZVitamin D assay for Clinical Chemistry Analyzers. Diazymes two ...
Level Descriptors:. The Clinical Laboratory Scientist job family consists of four levels which are distinguished based on the complexity of assigned duties, the expertise required to complete various assignments, and the responsibility assigned for providing leadership to others.. Level I Code: X14A Salary Band: J. This is the basic level of this job family where incumbents perform a wide variety of routine clinical laboratory tests.. Knowledge, Skills and Abilities required at this level include knowledge of the basic principles of chemistry, biology, and microbiology methods and techniques of laboratory analysis; of the hazards of laboratory activities and related safety practices; and of the principles of microbiological, immunological, and biochemical reagents and standard examinations. Ability is required to perform basic microbiological, immunological, and biochemical analysis; to establish and maintain effective working relationships with others; to follow instructions, both orally and in ...
I had the privilege of giving the keynote address to several hundred union members on April 26, 2014 at an event entitled "The Clinical Laboratory Scientist in the Modern Healthcare Delivery System". It was a wonderful and timely opportunity to share deep background on the underlying drivers of the health care crisis in our nation, how the PPACA and other market forces are driving health care transformation at an accelerated pace, and how members as frontline staff can contribute to successful change.. The event was sponsored by the Institute for Continuing Education of the 1199SEIU League Training and Upgrading Fund and 1199SEIU United Healthcare Workers East Professional and Technical Department. This program is part of the continuing education for tens of thousands of union members provided by the Union and its Training Funds. The venue was the John Jay College in Manhattan, but also included live video feed and webcast to hundreds of others who could not be present. Attendees included union ...
Hospital Main Campus is now hiring a Clinical Laboratory Scientist Flow Cytometry in Seattle, Washington. Review all of the job details and apply today!
Exciting opportunity in Madison, WI for Exact Sciences as a Lead Certified Clinical Laboratory Scientist - Tuesday - Friday, 8:00pm - 6:30am shift
Complete report $6,100. DataPack (test volumes, sales forecasts, supplier shares) $3,950.. 2016 Spain Clinical Chemistry and Immunodiagnostic Markets is a new strategic analysis of major business opportunities emerging in the Spanish clinical chemistry and immunodiagnostic markets during the nextfive years. The report explores future trends in the Spanish market; provides estimates of the specimen, test and sales volumes, as well as major suppliers sales and market shares; compares features of leading analyzers; profiles key competitors; and identifies specific product and marketing opportunities emerging during the next five years.. The report provides five-year volume and sales forecasts for over 100 clinical chemistry, TDM, endocrine, cancer, immunoprotein and abused drug assays performed in hospitals, commercial laboratories, physician offices, and ambulatory care centers, including controls, calibrators and consumables.. Rationale. The clinical chemistry and immunodiagnostic markets are ...
Clinical chemistry is generally concerned with the analysis of various markers in body fluids, mostly serum and plasma. Clinical chemistry is a crucial component in the early detection, treatment and management of human diseases and health disorders. The discipline uses a variety of techniques such as spectrophotometry, fluorometry, nephelometry, turbidimetry, electrochemistry, electrophoresis, chromatography, mass spectrometry, and immunoassay.. Our laboratory performs diagnostic tests such as cholesterol, lipids, lipoproteins, serum and fluid proteins, glucose and other carbohydrates, minerals, bone markers, cardiac markers, and tumor markers. We also perform tests to investigate the functions of thyroid, pituitary, adrenal, reproductive, pulmonary and renal systems, acid-base, water and electrolyte disorders, blood gases, pancreatic and intestinal functions, liver and biliary diseases, and nutritional deficiencies, therapy and monitoring. Clinical chemistry is front-and-center of diagnostics ...
Biography. Volkher Scharnhorst received his PhD for research on W1 proteins and their functions in growth and differentiation at the department of Medical Biochemistry at Leiden University in 2000. After his PhD he became a resident in clinical chemistry in the clinical laboratory of Máxima Medical Centre in Veldhoven. During his time as resident Volkher Scharnhorst became lecturer chemical pathology at the Fontys Hogeschool. He received his admission to the registry of clinical chemists in 2004 after which he became a clinical chemist at Atrium Medisch Centrum. In 2006, he continued his career in Catharina Hospital. In 2007, he was appointed member of the Medical Ethics Board (METC) and became head of the clinical laboratory of Catharina Hospital. His research focuses on use of biomarkers in diagnosing and monitoring disease with emphasis on improvement of analytical techniques and interpretation of test results. In 2012, the Technical University Eindhoven installed him as lecturer and in ...
An automated analyser is a medical laboratory instrument designed to measure different chemicals and other characteristics in a number of biological samples quickly, with or without minimal human assistance ...
Diazymes Ferritin Assay provides an effective test method for laboratories of virtually all sizes," said Dr. Chong Yuan, Managing Director of Diazyme Laboratories. "The sensitivity of the assay allows ferritin levels to be measured very efficiently and effectively. This high-throughput liquid stable assay provides precise test results, is user friendly, cost effective and has excellent correlation to the existing commercial methods." Diazyme Laboratories is a division of General Atomics headquartered in La Jolla, California. Diazyme uses its enzyme platform technologies to develop innovative assays for clinical and research uses with reduced costs and improved performance. Products include diagnostic blood tests for cardiac markers, diabetes, nutritional assessment, liver disease, renal disease and electrolytes. Information regarding Diazymes enzyme technology and related products can be found on its website at www.diazyme.com. ...
The Clinical Chemistry laboratory provides routine and state of the art specialized assays for patient care. The laboratory is open and staffed 24 hours a day, seven days a week, and tests of an urgent nature are available around the clock. One or more of the laboratory directors are available at all times for consultation and/or to facilitate use of the laboratorys services.. Clinical Chemistry laboratories generate over three million test results a year, offering assays for nearly 200 different clinically important constituents. Assays are carried out using a wide variety of techniques ranging from fully automated instruments to high performance liquid chromatography and tandem mass spectrometry.. ...
Assay developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc.. Die Produktverfügbarkeit/Spezifikationen können von Land zu Land variieren und unterliegen den jeweiligen regulativen Anforderungen. Für weitere Informationen wenden Sie sich bitte an den für Sie zuständigen Siemens Healthineers Mitarbeiter. ...
These biographical articles are commissioned to present the achievements of distinguished clinical chemists, as well as their philosophical views on their professional life and the field of clinical chemistry.
Some thoughts on practicing clinical chemistry in Canada As a Canadian training in the US, my desire has always been to return to Canada once I completed my fellowship. As the time draws nearer, however, I have come to realize that I dont actually know very much about what it means to be a clinical chemist in my home country. I suspected that there are some similarities with the US, and I knew for certain that there were differences. But what exactly were they?
Dedicated to achieving better health through laboratory medicine, the American Association for Clinical Chemistry, AACC, brings together more than 50,000 clinical laboratory professionals, physicians, research scientists, and business leaders from around the world focused on clinical chemistry, molecular diagnostics, mass spectrometry, translational medicine, lab management, and other areas of breaking laboratory science. Since 1948, AACC has worked to advance the common interests of the field, providing programs that advance scientific collaboration, knowledge, expertise, and innovation. For more information, visit www.aacc.org.. ...
Concerned by the 1995 paper of Reid et al. (3), I had made a list of the seven standards that they studied and used it as a checklist when working with authors of reports submitted to Clinical Chemistry. The first manuscript to which this checklist was applied contained six of the seven items of information on the list. The missing item was the imprecision of the test-and this was a manuscript from an investigator in the field of clinical chemistry, a specialty for which assessment of imprecision of assays is a part of ones being. The aphorism, "Mankind needs not so much to be educated as reminded", came to mind.. Other editors had become concerned with the quality of reporting of a different kind of clinical study, the randomized controlled trial (RCT) of drugs and other therapies. RCTs were (and are) highly influential, but the vulnerability to bias of a given study often could not be discerned from the published reports. In 1996, a group of medical journals published a key guideline and ...
Precision care is critical to clinical chemistry diagnostics. From general chemistry testing to toxicology and cardiac monitoring, the products featured in our Cardinal Health Clinical Chemistry portfolio accommodate the requirements of todays laboratories. Whether performing routine chemistry panels, tageted immunoassays, or molecular assays, we offer the product you need at the right price.
The hospital clinical chemistry and immunodiagnostic market is undergoing a significant transformation which is caused by the convergence of advanced and high end technologies, intensifying competition, the introduction of strict, new regulations, IT, automation, and engineering. Some of the segments such as routine chemistry are on the verge of already resembling the commodity market. In this type of market, cost per test and product positioning are much more critical and important than the underlying technology. Thus, this kind of budding marketplace thus creates lucrative opportunities for a range of new auxiliary products, reagent systems, and new instruments such as calibrators, controls, and specimen preparation devices. Hospital clinical chemistry is the field of clinical pathology which is related to the examination of the body such as urine, blood, etc. Immunodiagnostics is the method of diagnostic based on the antibody-antigen reaction.. The research report is a complete inspection of ...
Mexico Clinical Chemistry Reagents and Analyzers Market Analysis 2021: Supplier Strategies, Volume and Sales Forecasts, Technology and Instrumentation Review Mexico Clinical Chemistry Reagents and Analyzers - Market research report and industry analysis - 10899126
Israel Clinical Chemistry Reagents and Analyzers Market Analysis 2021: Supplier Strategies, Volume and Sales Forecasts, Technology and Instrumentation Review Israel Clinical Chemistry Reagents and Analyzers - Market research report and industry analysis - 10899106
www.MOLUNA.de Tietz Fundamentals of Clinical Chemistry and Molecular Diagnosti [4188307] - A condensed, student-friendly version of Tietz Textbook of Clinical Chemistry, this text uses a laboratory perspective to provide you with the chemistry fundamentals you need to work in a real-world, clinical lab. Accurate chemical structures are included to explain the key chemical features of relevant molecules. Offering complete, accurate coverage
This new report from VPGMarketResearch.com provides strategic assessments of major clinical chemistry and immunodiagnostic product suppliers and emerging market entrants. The report presents strategic profiles of 25 current and emerging suppliers of clinical chemistry and immunodiagnostic products, including their sales, market shares, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.. Contains 42 pages. ...
Our range of clinical chemistry reagents is extensive and is sure to meet your needs. As we invest heavily in research and development, our clinical chemistry portfolio is constantly expanding to provide you with an increased choice of high quality reagents ...
In article ,1b7cc$d224.3e at News_1,, carlg ,carlg at ultranet.com, says: , ,Does anyone know if there is a web page for the Journal ,of Clinical Chemistry or some way of getting an index ,online? , ,Thanks for your helpl. The table of contents for Clinical Chemistry is posted on the bionet.journals.contents news group and the bionet journals web pages. A direct web page is planned by the journal for sometime this year ...
Clinical chemistry , Clinical chemistry , کتابخانه دیجیتالی دانشگاه علوم پزشکی و خدمات درمانی شهید بهشتی
SKU: AP3877 Categories: Clinical Chemistry, Clinical Chemistry Analysers, Diagnostic Reagents, RX daytona, RX daytona and RX imola Reagents, RX imola, Veterinary Reagents Method: AMP Format: Lyophilised Size: R1 6x17.5ml, R2 6x3.5ml Assay Range: Measuring range 18.3 to 1117 U/l Working Stability: To expiry at +2 to +8℃ Available Applications: Applications are available for a wide range of instruments Tags: Assay, Clinical Chemistry Reagents, RX daytona, RX imola, Veterinary Reagents ...
The service is organized into a Laboratory Medicine section and a Pathology section. The Laboratory Medicine Section has 8 subsections: Chemistry, Hematology, Blood Bank, Microbiology, Molecular Diagnostics, Mycobacteriology, Virology, and Specimen Acquisition and Processing. The Mycobacteriology, Virology, and Molecular Diagnostics laboratories perform testing for the New England Veterans Integrated Service Network (VISN) and other VA facilities nationwide.. The Chemistry, Hematology, and Blood Bank are all open 24/7, though some testing services have limited availability on nights, weekends, and holidays. Microbiology is staffed during the day, 7 days a week. The Molecular Diagnostics, Virology, and Mycobacteriology laboratories are open during the day, M-F.. Four attending faculty cover the Laboratory Medicine Section. Faculty are available 24/7 for consultations and questions via the Laboratory Medicine resident on-service.. ...
The Joint Committee for Traceability in Laboratory Medicine or JCTLM is collaboration between the International Committee for Weights and Measures (CIPM), the International Federation for Clinical Chemistry and Laboratory Medicine (IFCC), and the International Laboratory Accreditation Cooperation (ILAC). The goal of the JCTLM is to provide a worldwide platform to promote and give guidance on internationally recognized and accepted equivalence of measurements in laboratory medicine and traceability to appropriate measurement standards. ...
Clinical laboratory technicians generate critical data for identifying and treating cancer, heart disease, diabetes and other illnesses.
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Trends in Clinical Chemistry Testing - The introduction of new instrumentation has made clinical laboratory testing less challenging for laboratory managers.
Postdoctoral Training Program in Clinical Chemistry OverviewProgram Length: Two yearsSession Dates: July 1 - June 30Program Structure: Series of hospital-based rotations as well as course work, tutorials and journal clubsEvaluation Methods: Direct Observation and Oral Exams
Postdoctoral Training Program in Clinical Chemistry OverviewProgram Length: Two yearsSession Dates: July 1 - June 30Program Structure: Series of hospital-based rotations as well as course work, tutorials and journal clubsEvaluation Methods: Direct Observation and Oral Exams
The following is a list of chemistry societies: Contents : Top A B C D E F G H I J K L M N O P Q R S T U V W X Y Z See also References Notes Alpha Chi Sigma (ΑΧΣ) American Association for Clinical Chemistry American Chemical Society American Crystallographic Association American Institute of Chemical Engineers (AIChE) American Institute of Chemists(AIC) American Oil Chemists Society American Society of Brewing Chemists American Society for Mass Spectrometry Association of Analytical Communities (AOAC International) Association of Greek Chemists Belgian Society of Biochemistry and Molecular Biology Biochemical Society Canadian Society for Chemical Technology (CSCT) Canadian Society of Clinical Chemists - (CSCC) Chemical Abstracts Service (CAS) Chemical Heritage Foundation (CHF) Chemical Institute of Canada (CIC) Chemical Society Located in Taipei (CSLT) Chemical Society of Japan (CSJ) Chemical Society of Nigeria (CSN) Chemical Society of Pakistan Chemical Society of Peru Chinese-American ...
Randox today announced that the Food and Drug Administration has cleared the companys HbA1c quality control, a product used to ensure accuracy in diagnosis and the ongoing monitoring of diabetes.. Randoxs Acusera HbA1c is a lyophilized control, enhancing stability and longevity, with assayed values provided for HPLC and a wide range of clinical chemistry analyzers. It is a 100% human whole blood control, which helps minimize matrix effects reducing lot-to-lot variations between batches. When reconstituted the control remains stable for 4 weeks at +2 - 8°C. The control is available in levels 1 and 2, and a calibrator is also available.. The FDA has also cleared for use two Randox clinical chemistry controls, namely Aldolase calibrator and controls, and Ammonia Ethanol control.. Acusera Aldolase calibrator and controls can be used when testing for liver damage as well as skeletal muscle diseases such as muscular dystrophy. Randox Aldolase control is available in levels 2 and 3 and is ...
A Committee on Standards was established in 1966 "to instigate and promote theoretical and practical developments in the field of standards and standardisation in clinical chemistry - in its broadest sense." During its first decade, the main efforts of the Committee were directed toward (1) analytical nomenclature, (2) reference materials and methods, and (3) quality control. Its achievements during this period are illustrated by the list of publications on these topics. Following a Council decision in 1978, efforts have been made to extend its work to include more subjects of interest both to clinicians and clinical chemists and laboratorians. Accordingly, the name of the Committee was changed to the Scientific Committee and later to the Scientific Division.. The Division and its activities are managed by an Executive Committee. This Committee is responsible for (1) developing a mission statement, (2) developing strategy and tactics, (3) initiating and managing projects, and (4) generating and ...
Dr. Gronowski is a Professor of Pathology & Immunology, and Obstetrics & Gynecology at Washington University School of Medicine (St. Louis Missouri). She is Associate Medical Director of the Clinical Chemistry and Serology & Immunology laboratories at Barnes-Jewish Hospital. Dr. Gronowski received her Ph.D. in Endocrinology- Reproductive Physiology from University of Wisconsin, and is a diplomate of the American Board of Clinical Chemistry. Dr. Gronowski is past president of the American Board of Clinical Chemistry and the American Association for Clinical Chemistry. Her research focuses primarily on the laboratory diagnostics of endocrinology and reproductive physiology with a particular emphasis on maternal fetal medicine. She edited the book entitled "Handbook of Clinical Laboratory Testing During Pregnancy". ...
Australia In Vitro Diagnostics (IVD) Market Outlook to 2024 - Clinical Chemistry, Genetic Testing, Hematology, Histology and Cytology, Immuno Chemistry, Infectious Diagnostics and Microbiology Culture is a market research report available at US $5995 for a Single User PDF License from RnR Market Research Reports Library.
India In Vitro Diagnostics (IVD) Market Outlook to 2024 - Clinical Chemistry, Genetic Testing, Hematology, Histology and Cytology, Immuno Chemistry, Infectious Diagnostics and Microbiology CultureGlobalDatas new report, India In Vitro
I. IDENTIFICATION: ( 1 PT. EACH). 1. The supernatant fluid when clotted blood has been centrifuged.. 2. The supernatant fluid when anti-coagulated blood has been centrifuged.. 3. The reference method for cholesterol.. 4. A process wherein a needle is introduced into a vein to obtain blood.. 5. The simplest form of carbohydrate.. 6. How many minutes do you centrifuge the blood for serum preparation?. 7. It is the precision and accuracy of a method.. 8. The reference method for glucose. 9. The normal pH of serum.. 10. The most common sample for clinical chemistry.. ANSWERS ARE FOUND IN THIS POST. ...
Synopsis: A condensed, student-friendly version of Tietz Textbook of Clinical Chemistry, this text uses a laboratory perspective to provide you with the chemistry fundamentals you need to work in a real-world, clinical lab. Accurate chemical structures are included to explain the key chemical features of relevant molecules. Offering complete, accurate coverage of key topics in the field, its everything that you expect from the Tietz name! ...
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Clinical Chemistry 2. Long -Quiz Laboratory. Spectrophotometer, Potassium & Chloride. Name:____________________________________________ Rating__________________. Date:_____________________________________________ Section:_________________. 1. __________________________________________ The best AC for potassium determination. (specify). 2. __________________________________________The best sample for chloride determination.(Specify). 3. __________________________________________Indicate whether potassium is n anion or cation.. 4. __________________________________________ Indicate whether chloride is n anion or cation.. 5. __________________________________________Indicate whether potassium is intracellular or extracellular.. 6. __________________________________________ Indicate whether chloride is intracellular or extracellular.. 7. __________________________________________Normal value for potassium in blood sample. 8. __________________________________________Normal value for chloride in ...
ON THE COVER Iron Heart. In the same way that iron rebar has contributed to the heart image here, in humans, iron makes an important contribution to heart health. Although iron is essential to the function of many tissues, iron is highly reactive and can cause oxidative stress and is sequestered by transferrin in blood and bound to ferritin in tissues. Hepcidin is also a regulator of iron, but there have been conflicting results about the relationship between hepcidin concentrations and cardiovascular mortality. This issue of Clinical Chemistry contains important results from the Ludwigshafen Risk and Cardiovascular Health Study where the authors investigated the role of iron metabolism and hepcidin in cardiovascular and total mortality in patients undergoing coronary angiography. (See page 849.) Reproduced with permission from Flickr/Mattias Rizzi. ...
Focuses specifically on understanding potential problems and sources of error in management of the clinical chemistry testing procedures, how to anticipate and avoid such problems, and how to manage them if they occur.
Clinical chemistry in the arena of paediatrics often involves some special concerns which are not commonly encountered in laboratories that perform testing on primarily adult populations
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CHEM 1013 General Chemistry I Exams (0 semester hours) Hour exams for CHEM 1311. Corequisites: CHEM 1111 and CHEM 1311. (0-0) S CHEM 1014 General Chemistry II Exams (0 semester hours) Hour exams for CHEM 1312. Corequisites: CHEM 1112 and CHEM 1312. (0-0) S CHEM 1111 (CHEM 1111) General Chemistry Laboratory I (1 semester hour) Introduction to the chemistry laboratory. Experiments are designed to demonstrate concepts covered in CHEM 1311; including properties and reactions of inorganic substances and elementary qualitative and quantitative analysis. Corequisites: CHEM 1013 and CHEM 1311. (0-3) S CHEM 1112 (CHEM 1112) General Chemistry Laboratory II (1 semester hour) A continuation of CHEM 1111 demonstrating the concepts covered in CHEM 1312, including acid base chemistry, reaction kinetics, electrochemistry, polymers, and organic synthesis. Prerequisite: CHEM 1111 or CHEM 1115. Corequisites: CHEM 1014 and CHEM 1312. (0-3) S CHEM 1115 Honors Freshman Chemistry Laboratory I (1 semester hour) This ...
Volpi develops, industrializes and manufactures optoelectronic module solutions for in vitro diagnostics and life science research (fluorescence, reflectometry, chemiluminescence, calorimetry, spectroscopy). Applications include modules for PCR, next-generation sequencing, immunoassay systems and clinical chemistry analyzers. Based in the USA and Switzerland, certified ISO 13485, Volpi provides comprehensive systems engineering combined with lean manufacturing throughout the product life cycle.. ...
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The WSMR Chemistry Laboratory is a modern, all purpose state-of-the-art facility with a varied menu of services for our Army, Navy, Air Force, NASA, Contractor, and Commercial customers. The scope of work within the facility is subdivided into two broad areas: Test Support and Environmental Analysis. Test Support services include: (1) Conformance testing of material such as petroleum, oil and lubricants, breathing air, missile and rocket propellants; (2) explosives analysis of bulk material and breakdown products; (3) failure analysis of mal-performing systems that have a potential chemical cause; (4) toxic/noxious gas testing for incursion of missile and rocket exhaust by-products into crew cab breathing zones (man-rating); (5) special chemical problems for which no standard testing protocol exists. Environmental measurements are dedicated to the analysis of hazardous wastes, wastewater, ground and surface water, and soil in accordance with Environmental Protection Agency procedures. The ...
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The Clinical Chemistry Laboratories provide routine analyses relying heavily on automated random access analyzers with multiple methodologies. A number of manual assays and urinalyses are also performed. Certain hormone assays, selected enzyme activity assays, serum tumor markers, various hepatitis tests, special amniotic fluid chemistries, glycosylated hemoglobin, as well as various infrequently ordered RIA, EIA and manual procedures are also provided.. Suggested reference ranges are provided for listed analytes in terms of conventional and System Internationale (SI) units. The reasons for using SI units in preference to conventional units are beyond the scope of this manual. In short, the international community of biochemists suggests using the liter (L) as the "volume" of choice and using the "mole" rather than the "gram" whenever possible in describing concentration values. However, concentration values are expressed in grams rather than moles in two general cases: 1) when the analyte being ...
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Since pharmacogenetic clinical recommendations are based on phenotype, the assignment of phenotype based on genotype is an important aspect to clinical implementation and reporting of different inferred phenotypes across laboratories and guidelines has created considerable confusion and inconsistencies in recommendations. To maximize the utility of pharmacogenetic test results, it is desirable to standardize the phenotype prediction from genotype data. The purpose of this project was to determine consensus among CYP2D6 experts as to the definitions used to assign CYP2D6 phenotype based on genotype.. ...
Glomerular disorders are an important cause of kidney disease in dogs and cats, but their diagnostic evaluation, classification, and management remain enigmatic and uncharacterized compared to other renal pathology. Accurate diagnosis of a patients glomerular disease provides insights into the disorders pathogenesis and prognosis, as well as guidelines for appropriate treatment. In human beings, specific glomerular diseases are characterized (and thus are identified) by their light microscopic, immunopathologic, and electron microscopic features which are correlated with the particular clinical and clinicopathologic findings that are exhibited by affected patients.. The purpose of this initiative is to employ the use of all three diagnostic modalities, used in human nephropathology, to accurately characterize glomerular disease in proteinuric dogs, and to relate these findings to clinicopathologic presentation and outcome. This is achieved by establishing an international network of ...
Glomerular disorders are an important cause of kidney disease in dogs and cats, but their diagnostic evaluation, classification, and management remain enigmatic and uncharacterized compared to other renal pathology. Accurate diagnosis of a patients glomerular disease provides insights into the disorders pathogenesis and prognosis, as well as guidelines for appropriate treatment. In human beings, specific glomerular diseases are characterized (and thus are identified) by their light microscopic, immunopathologic, and electron microscopic features which are correlated with the particular clinical and clinicopathologic findings that are exhibited by affected patients.. The purpose of this initiative is to employ the use of all three diagnostic modalities, used in human nephropathology, to accurately characterize glomerular disease in proteinuric dogs, and to relate these findings to clinicopathologic presentation and outcome. This is achieved by establishing an international network of ...
Non-viral Delivery Methods for Gene Therapy Main supervisor: Professor Edvard Smith, Karolinska institute, Department of Laboratory Medicine, Division of Clinical Research Center Specialists: Docent Lars Frelin, Karolinska institute, Department of Laboratory Medicine, Division of Clinical Microbiology Professor Einar Hallberg, Stockholm university, Department of Neurochemistry Docent Theocharis Panaretakis, Karolinska institute, Departmentof Oncology-Pathology
TY - JOUR. T1 - S100B protein increases in human blood and urine during stressful activity. AU - Gazzolo, Diego. AU - Florio, Pasquale. AU - Zullino, Emma. AU - Giovannini, Lia. AU - Scopesi, Fabio. AU - Bellini, Carlo. AU - Peri, Valentina. AU - Mezzano, Paola. AU - Petraglia, Felice. AU - Michetti, Fabrizio. PY - 2010/9/1. Y1 - 2010/9/1. KW - human biological fluids. KW - S100B. KW - stress. UR - http://www.scopus.com/inward/record.url?scp=77957306581&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=77957306581&partnerID=8YFLogxK. U2 - 10.1515/CCLM.2010.262. DO - 10.1515/CCLM.2010.262. M3 - Article. C2 - 20604725. AN - SCOPUS:77957306581. VL - 48. SP - 1363. EP - 1365. JO - Clinical Chemistry and Laboratory Medicine. JF - Clinical Chemistry and Laboratory Medicine. SN - 1434-6621. IS - 9. ER - ...
We look forward to receiving your manuscript! Hybrid Open Access For complete details on hybrid open access publishing at De Gruyter please see: https://www.degruyter.com/page/560 Effective 1st January 2016, authors from an institution affiliated with either the Association of Dutch Universities (VSNU), the Consortium of Swiss Academic Libraries or some UK libraries participating in the Jisc Collections SMP may publish primary research and review articles open access in any of De Gruyters OnlineOpen journals at a discount of 90% of the APC price. For more information and to confirm whether your institution is eligible please see the following: The Netherlands: https://www.degruyter.com/page/1461 ...
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ASQ/ANSI/ISO 7870-5:2014 establishes a guide to the use and understanding of specialized control charts in situations where commonly used Shewhart control chart approach to the methods of statistical control of a process may either be not applicable or less efficient in detecting unnatural patterns of variation of the process.. ...
Beacon Analytical Systems, Inc. ("Beacon") warrants the products manufactured by it against defects in materials and workmanship when used in accordance with the applicable instructions for a period not to extend beyond a products printed expiration date. BEACON MAKES NO OTHER WARRANTY, EXPRESSED OR IMPLIED. THERE IS NO WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. The warranty provided herein and the data, specifications and descriptions of Beacon products appearing in published catalogues and product literature may not be altered except by express written agreement signed by an officer of Beacon. Representations, oral or written, which are inconsistent with this warranty or such publications are not authorized and, if given, should not be relied upon.. In the event of a breach of the foregoing warranty, Beacons sole obligation shall be to repair or replace, at its option, any product or part thereof that proves defective in materials or workmanship within the warranty ...
Analytical systems and methods that use a modular interface structure for providing an interface between a sample substrate and an analytical unit, where the analytical unit typically has a particular interface arrangement for implementing various analytical and control functions. Using a number of variants for each module of the modular interface structure advantageously provides cost effective and efficient ways to perform numerous tests using a particular substrate or class of substrates with a particular analytical and control systems interface arrangement. Improved optical illumination and detection system for simultaneously analyzing reactions or conditions in multiple parallel microchannels are also provided. Increased throughput and improved emissions detection is provided by the present invention by simultaneously illuminating multiple parallel microchannels at a non-normal incidence using an excitation beam including multiple excitation frequencies, and simultaneously detecting emissions from
Please leave us your contact information so we can keep you updated on alumni activities and events, and reestablish your contact with other alumni and faculty.. With the national shortage of clinical laboratory scientists, we receive many phone calls and emails from facilities searching for qualified individuals. If you are interested in seeing these opportunities, let us know and we will include you in the electronic job postings.. ...
An analytical system comprised as a base unit, an adapter, and a sample substrate. The adapter is attached to an attachment region on the base unit, and the sample substrate is attached to an attachment region on the adapter. The adapter permits the base unit to be interfaced with a wide variety of different sample substrates to perform chemical and biological analytical analyses.
Dear All,. following the agreement on mutual cooperation between EFLM and W. de Gruyter for Clinical Chemistry and Laboratory Medicine journal (CCLM), it has been planned to send regularly to the EFLM contacts the table of contents of CCLM issues and the list of future titles as well. I do hope you will appreciate the initiative which is intended as a further service by EFLM to our European professional community. CCLM is published on a monthly basis and is the most relevant Journal on Clinical Chemistry in Europe; it is a valuable and updated source of knowledge for the professionals in the field, well recognized all over the world. The CCLM 2016 Impact Factor is 3.432.. With kindest regards ...
Evidence-based medicine as applied to laboratory medicine for laboratorians, clinicians, and other related health professionals working in the laboratory sciences.
This is a special course for science majors and minors who plan on pursuing a career in chemistry education at the secondary school level. Topics include laboratory and stockroom management, planning and running high school-level chemistry laboratory experiments, and mastery of chemistry content related to the high school curriculum. Students also have the opportunity to function as teaching assistants in lower-division chemistry laboratories. 2 hours lecture, 2 hours activity. (020153) ...
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WPA Lecture Series: Dr. Zia Khan (November 15, 2016) WPA started off our first Guest Lecture Series of the 2016-2017 school year with Dr. Zia Khan. As the Chair of BMSc Program in Pathology and the Director of Research of Pathology and Laboratory Medicine, Dr. Khans talk drew attendance from variety of undergraduate and graduate students. His personal speech about his journey into academia was inspiring and motivational. It was a reminder that the journey to reach our goals will be difficult, but the challenges will be worthwhile in the long run.. ...
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The Department of Pathology and Laboratory Medicine helps physicians and researchers better understand the causes and effects of given diseases and conditions to help determine treatment options.
The lab is presently particularly interested in two genes, JAZF1 and JJAZ1/SUZ12, which we discovered to be fused in the cells of certain uterine tumors. JJAZ1 is a Polycomb group gene, the product of which is essential for histone methylations that regulate chromatin remodeling and activity. We have investigated how the JAZF1-JJAZ1 fusion functions in oncogenesis and found that its action has features not previously described in cancer. Recently, we discovered that JAZF1-JJAZ1 RNA is produced by hormonally regulated trans-splicing between the pre-mRNAs for the two genes in normal endometrium. This discovery has led us to explore other examples of recombination between RNAs, which is much more common than previously thought. Relative to JJAZ1, little is known about the function of JAZF1, although single nucleotide polymorphisms in this gene are associated with altered risk for type 2 diabetes and prostate cancer. We are currently investigating the mechanisms of these associations ...
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Clinical Chemistry. 2000 Nov;46(11):1787-95. Paul BD, McWhorter LK, Smith ML. Electron ionization mass fragmentometric ...
The early years of discovery". Clinical Chemistry. 43 (4): 680-5. PMID 9105273.. ... "The Journal of Biological Chemistry. 223 (2): 897-905. PMID 13385237.. *^ Burns JJ, Moltz A, Peyser P (December 1956). "Missing ... "Frontiers in Chemistry. 5: 50. Bibcode:2017FrCh....5...50M. doi:10.3389/fchem.2017.00050. PMC 5504230. PMID 28744455.. ... "The American Journal of Clinical Nutrition. 54 (6 Suppl): 1135S-1140S. doi:10.1093/ajcn/54.6.1135s. PMID 1720597.. ...
"Clinical Chemistry. 56 (2): 202-11. doi:10.1373/clinchem.2009.134858. PMID 19926773.. ... "Clinical Journal of the American Society of Nephrology. 3 (5): 1542-7. doi:10.2215/CJN.01220308. PMC 4571147. PMID 18562594.. ... "The Journal of Clinical Endocrinology and Metabolism. 95 (3): 1076-83. doi:10.1210/jc.2009-1797. PMC 2841532. PMID 20061416.. ... "The Journal of Clinical Endocrinology and Metabolism. 93 (9): 3381-8. doi:10.1210/jc.2007-2702. PMC 2567851. PMID 18593774.. ...
"Clinical Chemistry. 46 (7): 976-988.. CS1 maint: Uses authors parameter (link) ... "Journal of Materials Chemistry. 16 (33): 3391-3395. doi:10.1039/B607022A.. *^ "Olive Oil Times". Retrieved September 13, 2014. ... Moore J, Kelsberg G, Safranek S (December 2012). "Clinical Inquiry: Do any topical agents help prevent or reduce stretch marks ... a meta-analysis of 26 clinical trials reported that high-polyphenol olive oil improved measures of total cholesterol, HDL ...
"Clinical Chemistry. 40 (3): 411-6. PMID 8131277.. *^ Stahl W, Schwarz W, Sundquist AR, Sies H (April 1992). "cis-trans isomers ... "Clinical Microbiology Reviews. 10 (1): 1-18. PMC 172912 . PMID 8993856.. *^ Chaudière J, Ferrari-Iliou R (1999). "Intracellular ... "The Journal of Biological Chemistry. 265 (26): 15361-4. PMID 2394726.. *^ Padayatty SJ, Katz A, Wang Y, Eck P, Kwon O, Lee JH, ... "The Journal of Biological Chemistry. 269 (13): 9397-400. PMID 8144521.. *^ Wells WW, Xu DP, Yang YF, Rocque PA (September 1990 ...
Chemistry. 135 Clinical Medicine. 135 Computer Science. 92 Economics & Business. 85 Engineering. 152 ... These include a parade, a magic show performed by the chemistry department, the Doxie Derby (dachshund races), film screenings ...
Clinical Chemistry. 56 (7): 1119-1127. doi:10.1373/clinchem.2009.141549. PMID 20448188. Bohr, Vilhelm; R. Michael Anson (1999 ...
Clinical Chemistry. 47 (4): 624-630. ISSN 0009-9147. PMID 11274010. Leong, Anthony S-Y; Cooper, Kumarason; Leong, F Joel W-M ( ... Clinical Chemistry. 47 (4): 624-630. ISSN 0009-9147. PMID 11274010. Thomas SN, Zhu F, Schnaar RL, Alves CS, Konstantopoulos K ( ... Clinical Chemistry. 47 (4): 624-630. Maestranzi, S.; Przemioslo, R.; Mitchell, H.; Sherwood, RA. (Jan 1998). "The effect of ... However, the serum levels are raised in some types of cancer, which means that it can be used as a tumor marker in clinical ...
Clinical Chemistry. 54 (1): 77-85. doi:10.1373/clinchem.2007.089896. PMID 18024531.. ... Tuch BE (September 2006). "Stem cells--a clinical update". Australian Family Physician. 35 (9): 719-21. PMID 16969445.. ... "Embryonic Stem Cell Therapy At Risk? Geron Ends Clinical Trial". ScienceDebate.com. Retrieved 2011-12-11.. ... Risks and Ethical Considerations in Translation of Stem Cell Research to Clinical Applications in Parkinson's Disease". Journal ...
Clinical Chemistry. 47 (12): 2164-5. PMID 11719487. Burbos, Nikolaos; Shiner, Alice M.; Morris, Edward (2008). "Severe ...
Clinical chemistry. Normal Plasma immunoglobulins. Normal Haematology. Normal Peripheral blood lymphocytes. Normal ... Clinical significance[edit]. MYH9-related disease. Mutations in MYH9 cause a Mendelian autosomal-dominant disorder known as ... The recent definition of genotype-phenotype correlations allows prediction of the clinical evolution of the disease in most ... The Journal of Biological Chemistry. 279 (40): 41263-6. doi:10.1074/jbc.C400352200. PMID 15292239.. ...
Clinical chemistry. Normal Plasma immunoglobulins. Normal Haematology. Normal Peripheral blood lymphocytes. Normal ... The Journal of Biological Chemistry. 237: 2611-9. PMID 13895983.. *^ Yehudai-Resheff S, Zimmer SL, Komine Y, Stern DB (March ...
Clinical Chemistry. 20 (1): 36-40. PMID 4809470.. *. Morris, L. J. (1966). "Separations of lipids by silver ion chromatography ... Ion Exchange in Analytical Chemistry International Series of Monographs in Analytical Chemistry. Burlington: Elsevier Science. ... Clinical utility[edit]. A use of ion chromatography can be seen in the argentation ion chromatography.[citation needed] Usually ... 1992). "Ion Chromatography the State of the Art". Analytical Chemistry. 64 (15): 775A-783A. doi:10.1021/ac00039a722.. ...
Clinical Chemistry. 45 (5): 593-615. PMID 10222345.. *^ "GE Healthcare Life Sciences, Immobilized lectin". Archived from the ... Luppa, Peter (2018). Point-of-care testing : principles and clinical applications. Berlin, Germany: Springer. pp. 71-72. ISBN ... Clinical adaptations have applied this type of chromatography for use in determining long term assessment of diabetic patients ... "Affinity Chromatography: A Review of Clinical Applications" (PDF) ...
Clinical Chemistry. 29 (8): 1474-1479. PMID 6191885.. CS1 maint: multiple names: authors list (link). ... Journal of Radioanalytical and Nuclear Chemistry Articles. 115 (2): 263-288. doi:10.1007/BF02037443. ISSN 0236-5731.. ... Journal of Radioanalytical and Nuclear Chemistry. 263 (1): 13-18. doi:10.1007/s10967-005-0004-6. ISSN 0236-5731.. ...
Clinical chemistry. Normal. Haematology. Normal. Peripheral blood lymphocytes. Normal. Micronucleus test. Normal. ... Clinical significance[edit]. Chromosomal rearrangements and altered expression of this gene have been implicated in several ... Its potential clinical use in the therapeutic decision making process is substantiated by a vast body of literature validating ... In the adult organism it is usually elevated due to nervous system damage, which makes it a potential clinical marker. ...
Clinical Chemistry. 36 (2): 225-9. PMID 2137384.. *^ Lawen A (October 2015). "Biosynthesis of cyclosporins and other natural ... Clinical Journal of the American Society of Nephrology. 4 (2): 481-508. doi:10.2215/CJN.04800908. PMID 19218475.. ... "Journal of Clinical Investigation. 120 (10): 3680-7. doi:10.1172/JCI43171. PMC 2947235 . PMID 20890047.. ... "Clinical Drug Investigation. 33 (1): 25-34. doi:10.1007/s40261-012-0029-x. PMC 3586182 . PMID 23179472.. ...
2009). "Next Generation Sequencing: From Basic Research to Diagnostics". Clinical Chemistry. 55 (4): 41-47. doi:10.1373/ ...
Clinical chemistry. Normal Haematology. Normal Peripheral blood lymphocytes. Normal Heart weight. Normal ... The Journal of Biological Chemistry. 275 (30): 22780-9. doi:10.1074/jbc.M001500200. PMID 10807909.. ... The Journal of Biological Chemistry. 276 (42): 39067-75. doi:10.1074/jbc.M104831200. PMID 11495908.. ...
"Clinical Chemistry. 43 (11): 2091-8. PMID 9365393.. *^ a b von Deutsch DA, Abukhalaf IK, Lapu-Bula R (15 October 2003). " ... Chemistry[edit]. Main article: Dihydrotestosterone § Chemistry. See also: List of androgens/anabolic steroids and List of ... It reached phase II clinical trials for hypogonadism and BPH and phase III clinical studies for cachexia but development was ... Hohl A (30 March 2017). Testosterone: From Basic to Clinical Aspects. Springer. pp. 91-. ISBN 978-3-319-46086-4. .. ...
Clinical Chemistry. 52 (9): 1679-1684. doi:10.1373/clinchem.2005.058040. PMID 16873295.. ... Canadian Diabetes Association Clinical Practice Guidelines Expert Committee. Canadian Diabetes Association 2003 Clinical ... "BMJ (Clinical Research Ed.). 350: h102. doi:10.1136/bmj.h102. PMC 4301599. PMID 25609400.. ... "BMJ (Clinical Research Ed.). 319 (7219): 1223-7. doi:10.1136/bmj.319.7219.1223. PMC 28269. PMID 10550081.. ...
Clinical Chemistry. 10 (12): 1117-20. PMID 14240747.. *^ Travis, John C.; Zwinkels, JC; Mercader, F; Ruíz, A; Early, EA; Smith ...
"Discontinuation of the bleeding time test without detectable adverse clinical impact". Clinical Chemistry. 47 (7): 1204-1211. ... "The preoperative bleeding time test lacks clinical benefit: College of American Pathologists' and American Society of Clinical ... "The preoperative bleeding time test lacks clinical benefit: College of American Pathologists' and American Society of Clinical ... "Blood Chemistries". Archived from the original on August 14, 2007. Retrieved 2009-01-02. Schafer, Andrew I.; Loscalzo, Joseph ( ...
Roberts, R; Stewart, AF (January 2012). "9p21 and the genetic revolution for coronary artery disease". Clinical Chemistry. 58 ( ... "World Journal of Clinical Cases. 3 (2): 163-70. doi:10.12998/wjcc.v3.i2.163. PMC 4317610 . PMID 25685763.. ... "BMJ (Clinical Research Ed.). 349: g4490. doi:10.1136/bmj.g4490. PMC 4115152 . PMID 25073782.. ... Numerous clinical trials were performed, either applying protein (angiogenic growth factor) therapies, such as FGF-1 or VEGF, ...
... of the American Association for Clinical Chemistry,[5][6] which later evolved into an area committee of the Clinical and ... "Clinical Chemistry 46, No. 5, 2000, pgs. 246-250" (PDF). Archived (PDF) from the original on 2011-06-07. Retrieved 2009-02-20. ... "The Clinical Chemist: Masahide Sasaki, MD, PhD (August 27, 1933 - September 23, 2005)". Clinical Chemistry. 52 (4): 791-792. ... Laboratories devoted to activities such as high-throughput screening, combinatorial chemistry, automated clinical and ...
Clinical and Experimental Immunology. May 2014, 176 (2): 266-74. PMC 3992039. PMID 24450998. doi:10.1111/cei.12277.. ... The Journal of Biological Chemistry. December 2015, 290 (51): 30204-11. PMC 4683245. PMID 26468291. doi:10.1074/jbc.R115.685990 ... The Journal of Clinical Investigation. 2007-05, 117 (5): 1119-1127. ISSN 0021-9738. PMC 1857272. PMID 17476341. doi:10.1172/ ... Clinical Immunology. 2012-02-10, 142 (2): 105-106. doi:10.1016/j.clim.2011.11.009 (英语).. ...
The Clinical Chemistry Branch (CCB) develops and improves methods for assessing disease status associated with and the risk for ... Ultimately, the findings from these research studies are translated into clinical applications, thus enabling doctors to tailor ...
Investigations: Essential clinical chemistry. BMJ 2003; 327 doi: https://doi.org/10.1136/sbmj.0309314 (Published 01 September ... William Marshall, reader and honorary consultant in clinical biochemistry1. *. 1Guys, Kings, and St Thomass School of ... Suneeta Kochhar fourth year medical student, William Marshall reader and honorary consultant in clinical biochemistry ... Suneeta Kochhar and William Marshall kick off a new series on basic clinical investigations. They explain what biochemistry ...
An automated analyser is a medical laboratory instrument designed to measure different chemicals and other characteristics in a number of biological samples quickly, with or without minimal human assistance ...
National Jewish Health Advanced Diagnostic Laboratories offer a comprehensive menu of clinical chemistry and hematology ... Clinical Chemistry and Hematology Tests. *Chemistry panels, including metabolic, comprehensive, anemia and lipid profiles ... Our clinical chemistry and hematology tests are available for clinical diagnostics and research studies. ... Routine Laboratory Testing: Clinical Chemistry & Hematology. Ronald Joseph Harbeck, PhD, Director. National Jewish Health ...
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Purchase Advances in Clinical Chemistry, Volume 32 - 1st Edition. Print Book & E-Book. ISBN 9780120103324, 9780080566306 ... Advances in Clinical Chemistry, Volume 32 1st Edition. 0.0 star rating Write a review ... Every informed laboratory staff must have available a copy of this volume. --Clinical Chemistry For more than thirty years, ... Each volume of Advances in Clinical Chemistry contains an index, and each chapter includes references. ...
... research scientists and other individuals involved with clinical chemistry and related disciplines. Founded in 1948, the ... AACCs vision is to provide leadership in advancing the practice and profession of clinical laboratory science and its ... AACC offers many programs that address the scientific, clinical, technical, and management challenges facing laboratory ... AACC is an international scientific/medical society of clinical laboratory professionals, physicians, ...
U.S.A., Total Clinical Chemistry and Immunoassay. Reagent Market Forecast By Test Category. U.S.A., Clinical Chemistry and ... U.S.A., Total Clinical Chemistry and Immunoassay. Test Volume Forecast By Test Category. U.S.A., Routine Chemistry Test Volume ... 2014 Opportunities in the US Clinical Chemistry and Immunodiagnostic Market is a new strategic analysis of major business ... U.S.A., Major Suppliers of Clinical Chemistry. Analyzers, Estimated Instrument Sales and Market Shares. U.S.A., Major Suppliers ...
... of Clinical Chemistry or some way of getting an index ,online? , ,Thanks for your helpl. The table of contents for Clinical ... Previous message: Journal of Clinical Chemistry *Next message: Distributor seeks new products: microbiology and clinical ... Previous message: Journal of Clinical Chemistry *Next message: Distributor seeks new products: microbiology and clinical ... Journal of Clinical Chemistry. Robert Rej bobrej at wadsworth.org Fri Jan 12 08:59:37 EST 1996 * ...
Newswise registered institution American Association for Clinical Chemistry (AACC) up-to-the-minute news, press releases, and ... the American Association for Clinical Chemistry, AACC, brings together more than 50,000 clinical laboratory professionals, ... AACCs Journals, Clinical Chemistry and The Journal of Applied Laboratory Medicine, to Be Published through Oxford University ... Breaking Research in AACCs Clinical Chemistry Journal Debunks the Claim That Vitamin D and Fish Oil Supplements Reduce ...
Congress of Clinical Chemistry and Laboratory Medicine / 10th Annual Meeting of the German Society for Clinical Chemistry and ... Clinical Chemistry and Laboratory Medicine (CCLM). Published in Association with the European Federation of Clinical Chemistry ... Congress of Clinical Chemistry and Laboratory Medicine. *Non-invasive prenatal diagnostics of aneuploidy using next-generation ... Current and future use of "dried blood spot" analyses in clinical chemistry by Lehmann, Sylvain/ Delaby, Constance/ Vialaret, ...
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Congress of Clinical Chemistry and Laboratory Medicine / 10th Annual Meeting of the German Society for Clinical Chemistry and ... Clinical Chemistry and Laboratory Medicine (CCLM). Published in Association with the European Federation of Clinical Chemistry ... Current and future use of "dried blood spot" analyses in clinical chemistry by Lehmann, Sylvain/ Delaby, Constance/ Vialaret, ... Non-invasive prenatal diagnostics of aneuploidy using next-generation DNA sequencing technologies, and clinical considerations ...
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  • The report provides five-year volume and sales forecasts for over 100 clinical chemistry, TDM, endocrine, cancer, immunoprotein and abused drug assays performed in hospitals, commercial laboratories, physician offices, and ambulatory care centers, including controls, calibrators and consumables. (prnewswire.com)
  • The CLSI ® guideline was written to ensure the use of a basic level of water purity so that clinical chemistry assays could be run safely. (sigmaaldrich.com)
  • General chemistry, electrolyte, lipid and protein assays seek to measure ions (e.g. (sigmaaldrich.com)
  • In general, the requirements that apply to water used in the genomics field also apply to water used by clinical laboratories performing these types of assays. (sigmaaldrich.com)
  • This range includes a large selection of clinical chemistry assays, controls and calibrators, which are fully compatible with most major brand open channel chemistry analyzers, including the Altair™ 240. (news-medical.net)
  • Extensive test menu covers a full range of assays and applications, including basic chemistries, electrolytes, enzymes, full lipid profiles, and derived tests. (dotmed.com)
  • In this review, we provide a brief outline of the metabolism of lactate, the pathophysiology of lactic acidosis, the clinical significance of D-lactate, the role of lactate measurement in acutely ill patients, the methods used to measure lactate in blood or plasma and some of the methodological issues related to interferences in these assays, especially in the case of ethylene glycol poisoning. (degruyter.com)
  • An actual experience involving a clinical chemist who needed assistance interpreting complex automated serology assays, and a microbiologist who had to figure out all of the numbers and quality metrics associated with automated chemistry analyzers, is what inspired the idea for this session. (aacc.org)
  • Now that the Ebola virus has arrived in the U.S., the ability of clinical laboratories to quickly identify patients who need treatment and require isolation will play a critical role in preventing an outbreak. (newswise.com)
  • Phase 1 consists of a 12 month series of rotations through clinical chemistry laboratories in the Department of Laboratory Medicine at MSKCC and Columbia University Medical Center. (mskcc.org)
  • According to the American Society of Clinical Pathologists, more than five billion tests are performed yearly in today's laboratories. (vinu.edu)
  • Clinical chemistry in the arena of paediatrics often involves some special concerns which are not commonly encountered in laboratories that perform testing on primarily adult populations. (els.net)
  • The new technology aims to introduce digital chemistry into clinical lab management through powerful data intelligence, operational improvements, and a new standard for quality and efficiency that will help clinical laboratories keep up with the ever-changing landscape of global healthcare. (mddionline.com)
  • Current President is Michael Bennett, PhD, and the association headquarters are located in Washington, D.C. (United States) AACC's approximately 8,000 members come from all areas of lab medicine-clinical and research laboratories, diagnostic companies, government agencies, original equipment manufacturers, and more. (wikipedia.org)
  • The journal covers developments in fundamental and applied research into science related to clinical laboratories. (wikipedia.org)
  • While still in high school, Arnold started his own business, "Bloomington Research Laboratories", doing analytic chemistry for the local gas company. (wikipedia.org)
  • The Express Plus clinical chemistry analyzer is a fully automated walk away system designed for maximum productivity, convenience and reliability. (bio-medicine.org)
  • A clinical analyzer for determining the presence or amount of an analyte in a sample includes at least one reagent supply and at least one reaction containment device for containing a volume of sample and a volume of said at least one reagent from said at least one reagent supply. (google.com)
  • EKF Diagnostics, the global in vitro diagnostics company, launched the Altair™ 240 clinical chemistry analyzer to the European market at Medica 2015, Düsseldorf, 16-19th November. (news-medical.net)
  • Retrieved on April 08, 2020 from https://www.news-medical.net/news/20151110/New-clinical-chemistry-analyzer-launched-by-EKF-at-Medica-2015.aspx. (news-medical.net)
  • He was active in the Spectroscopy Society and the Society of Analytical Chemists, and was one of the organizers of the first Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (PITTCON), held in 1950. (wikipedia.org)
  • At its inception as a tool of analytical chemistry, LC-MS/MS spread rapidly and indeed continues to do so in (amongst others) bioanalytical fields, owing to its selectivity for analytes of interest. (wikipedia.org)
  • The CV or RSD is widely used in analytical chemistry to express the precision and repeatability of an assay. (wikipedia.org)
  • Among other publications, he co-authored the books Course Notes on the Interpretation of Infrared and Raman Spectra (2004) and A Philatelic Ramble Through Chemistry (1998). (wikipedia.org)
  • In 1998 he co-authored the standard work in this area, A Philatelic Ramble Through Chemistry with Edgar Heilbronner. (wikipedia.org)
  • These volumes clarify the areas of molecular biology, informatics, and the monitoring of physiological parameters in critical situations as they pertain to clinical chemistry. (elsevier.com)
  • Current projects include: Visiting Lecturer Program Clinical Molecular Biology Courses Expanding knowledge in Evidence Based Medicine Managing the quality of Laboratory tests Courses and workshops in specialized areas Its mission is to provide worldwide communication about the work of IFCC to clinical laboratory scientists, physicians and health policy -makers and to provide continuing education, materials and services. (wikipedia.org)
  • Herzenberg was born in New York City, U.S.A.. He received his bachelor's degree in 1952 from Brooklyn College in biology and chemistry. (wikipedia.org)
  • Mendel studied classics, economics and the humanities, as well as biology and chemistry at Yale University and graduated with honors in 1891. (wikipedia.org)
  • Following Swiss tradition, she was educated at home with her brothers: her studies included Latin (essential for the sciences), chemistry, biology, and history, as well as topics more usual for young ladies in England. (wikipedia.org)
  • Laboratory robotics is the act of using robots in biology or chemistry labs. (wikipedia.org)
  • Since 1935, ion exchange chromatography rapidly manifested into one of the most heavily leveraged techniques, with its principles often being applied to majority of fields of chemistry, including distillation, adsorption, and filtration. (wikipedia.org)
  • When Jane became interested in learning more about chemistry, they conducted experiments together in a home laboratory, discussing the scientific principles involved. (wikipedia.org)
  • Ortho-Clinical Diagnostics, Inc. (google.com)
  • Ortho Clinical Diagnostics, a global leader in diagnostic platforms and technologies, recently announced that its new digital chemistry system known as the VITROS XT 7600 has received the CE mark ahead of its launch overseas. (mddionline.com)
  • Typically students in clinical pharmaceutical chemistry use the same curriculum as medical students, but specialize in medicinal and organic chemistry after and during the theoretical/early clinical studies. (wikipedia.org)
  • As a result, Beckman changed his major from organic chemistry to physical chemistry, where he worked with Worth Rodebush, T. A. White, and Gerhard Dietrichson. (wikipedia.org)
  • In 1905 she moved to the University of Chicago, pursuing a doctorate in organic chemistry. (wikipedia.org)
  • While there, he abandoned the dream of becoming a doctor, and during his sophomore year, he consumed organic chemistry, earning a bachelor's degree in three years, followed by his master's in 1904. (wikipedia.org)
  • Then Mendel found a position for McCollum at the University of Wisconsin-Madison, not in his preferred organic chemistry, but as an instructor in agricultural chemistry. (wikipedia.org)
  • Researchers demonstrate that plasma is preferable for prospective clinical applications of liquid biopsy. (aacc.org)
  • Although a liquid biopsy of circulating tumor cells has been validated and approved by the FDA as a useful prognostic method for various types of cancer, its clinical implementation is not yet widespread. (wikipedia.org)
  • Each volume of Advances in Clinical Chemistry contains an index, and each chapter includes references. (elsevier.com)
  • Advances in addressing the very large numbers of clinical samples that arise on routine screening programs such as those involved in inborn errors of metabolism studies are discussed. (wiley.com)
  • Chris Anfinsen, Richards's friend and his colleague as editors of Advances in Protein Chemistry and who recommended the Carlsberg Lab to him, was also an avid sailor, and they sometimes joined forces. (wikipedia.org)
  • From radiation therapy to clinical trials to check-ins with your doctor, your care is made as convenient as possible. (mskcc.org)
  • Clinical trials are arguably the most important steps in proving drug effectiveness and safety for public use. (wiley.com)
  • Clinical Trials Handbook provides a comprehensive and thorough reference on the basics and practices of clinical trials. (wiley.com)
  • With unique information on such current issues as adverse event reporting (AER) systems, adaptive trial designs, and crossover trial designs, Clinical Trials Handbook will be a ready reference for pharmaceutical scientists, statisticians, researchers, and the many other professionals involved in drug development. (wiley.com)
  • Clinical trials are invaluable in testing new treatments, drugs and technologies. (mcw.edu)
  • We're challenging existing models of care with new ideas across the spectrum of discovery-from basic science, to clinical trials, to public policy changes. (mcw.edu)
  • Clinical trials have found possible efficacy in those with post-traumatic stress disorder (PTSD). (wikipedia.org)
  • A 2014 meta analysis of 21 clinical trials of venlafaxine for the treatment of depression in adults found that compared to placebo, venlafaxine reduced the risk of suicidal thoughts and behavior. (wikipedia.org)
  • Clinical chemistry is front-and-center of diagnostics in patient care. (mcw.edu)
  • Chromatography has a vast array of clinical applications, and though the chromatographic methods were first introduced decades ago, new applications of this technology are being used to explore previously inaccessible frontiers in clinical diagnostics and toxicological testing. (wiley.com)
  • Functional staging has the advantage of evaluating the whole liver and directly measuring hepatic function that determines many clinical outcomes. (wikipedia.org)
  • eTBLAST is a now-defunct free text similarity service search engine which offered access to the MEDLINE database, the National Institutes of Health (NIH) CRISP database, the Institute of Physics (IOP) database, Wikipedia, arXiv, the NASA technical reports database, Virginia Tech class descriptions and a variety of databases of clinical interest. (wikipedia.org)
  • Built upon the foundation of the 14-part Guide to Scientific Writing , which focuses on how to organize and write a scientific paper, the Clinical Chemistry Guide to Manuscript Review will help scientists better understand what editors, journals, and even authors want in a peer review. (aacc.org)
  • Ultimately, the findings from these research studies are translated into clinical applications, thus enabling doctors to tailor treatment for their patients. (cdc.gov)
  • Clinical Applications of Mass, pp. 27-36. (els.net)
  • An up-to-date book devoted to clinical and toxicological applications of chromatographic methods will serve as an instructional and reference text, useful to students, laboratory technicians, and researchers. (wiley.com)
  • Aimed at both undergraduate and postgraduate readers, this unique text provides readers with a fully-integrated presentation of all aspects of the science of anticancer drugs, including their chemistry, pharmacology, and clinical applications. (wiley.com)
  • She will also discuss future applications, and how the partnership with chemistry can play into that technology sharing. (aacc.org)
  • New Diagnostic Methods for Inflammations of the Human Central Nervous System by Cerebrospinal Fluid Analysis, Workshop Conference of the German Society for Clinical Chemistry, Marburg a. d. (degruyter.com)
  • In clinical chemistry it has been suggested as a proliferation marker for prognosis, verification of diagnosis, control of treatment (particularly as a companion diagnostic) and follow-up of malignant disease. (wikipedia.org)
  • Diagnostic dilemmas in which different diseases may present with similar clinical signs and laboratory data are also included. (routledge.com)
  • He was initiated into Zeta Chapter of Alpha Chi Sigma, the chemistry fraternity, in 1921 and the Gamma Alpha Graduate Scientific Fraternity in December 1922. (wikipedia.org)
  • Capping his illustrious career Mendel was appointed Sterling Professor of Physiological Chemistry in 1921. (wikipedia.org)
  • Mendel wrote many articles and published Changes in the Food Supply and Their Relation to Nutrition (1916) and Nutrition, the Chemistry of Life (1923). (wikipedia.org)
  • Biologically, fructosamines are recognized by fructosamine-3-kinase, which may trigger the degradation of advanced glycation end-products (though the true clinical significance of this pathway is unclear). (wikipedia.org)