Models, Chemical

Chemical Phenomena

Multiple Chemical Sensitivity

Chemical Industry

Magnetic Resonance Spectroscopy

Chemical Warfare

Organic Chemicals

Hazardous Substances

Inorganic Chemicals

Burns, Chemical

Molecular Structure

Chemical Warfare Agents

Water Pollutants, Chemical

Environmental Pollutants

Databases, Chemical

Chemistry

Molecular Sequence Data

Models, Molecular

Carcinogens

Nuclear Magnetic Resonance, Biomolecular

Toxicity Tests

Xenobiotics

Small Molecule Libraries

Structure-Activity Relationship

Endocrine Disruptors

Mass Spectrometry

Kinetics

Toxicology

Chromatography, High Pressure Liquid

Sympathectomy, Chemical

Gas Chromatography-Mass Spectrometry

Amino Acid Sequence

Cross-Linking Reagents

Environmental Exposure

Phenols

Binding Sites

Stimulation, Chemical

Chemical Terrorism

Protein Conformation

Oils, Volatile

Evolution, Chemical

Mutagens

Molecular Conformation

Animal Testing Alternatives

Drug Evaluation, Preclinical

Amino Acids

Environmental Monitoring

Models, Biological

Pesticides

Carcinogenicity Tests

Irritants

Protein Binding

Oxidation-Reduction

Escherichia coli

Biological Assay

Temperature

Plant Extracts

Mutagenicity Tests

Hydrocarbons

Water

Glycosides

Dose-Response Relationship, Drug

Indicators and Reagents

Chemical Hazard Release

Solvents

Proteins

Time Factors

High-Throughput Screening Assays

Chemical Fractionation

United States Environmental Protection Agency

Drug Design

Spectrophotometry, Ultraviolet

Pharmaceutical Preparations

Occupational Exposure

Stereoisomerism

Diethyl Pyrocarbonate

Chemical Engineering

Catalysis

Spectrometry, Mass, Fast Atom Bombardment

Spectrophotometry, Infrared

Base Sequence

Ecotoxicology

Quantitative Structure-Activity Relationship

Physicochemical Phenomena

Carbohydrates

Chromatography, Thin Layer

Thermodynamics

Benzhydryl Compounds

Chemistry, Physical

Peptides

Hydrolysis

Chemistry Techniques, Analytical

Drug Discovery

Mutation

Environmental Pollution

DNA

Surface Properties

Hydrocarbons, Halogenated

Nitrogen Isotopes

Cysteine

Hot Temperature

Tetrahydrocannabinol

Lye

JEL classification codes

Kimetsan

Industrial organization

Tony Clement

Occupational exposure limit

Dextromethorphan

Dawa Limited

Quantitative structure-activity relationship

4-Methoxybutyrfentanyl

FKBP

MDMB-CHMICA

Ablation

Proline racemase

Alpha-Pyrrolidinopentiophenone

5F-EMB-PINACA

List of psychoactive plants

Ozanimod

Equilibrium chemistry

Crosslinking of DNA

List of benzodiazepines

5F-APINACA

N-Ethylbuphedrone

BET inhibitor

Government Pharmaceutical Organization

Coenzyme Q10

Diabetes mellitus type 1

Serotonin releasing agent

Phototoxicity

Federal Insecticide, Fungicide, and Rodenticide Act

Levomethamphetamine

100,000,000 Guinea Pigs

Type 2 diabetes

Budipine

2,3-Bisfosfoglicerinska kiselina

Indinavir

Alternative medicine

Αμινά Γκουρίμπ - Βικιπαίδεια

QIAGEN Silicon Valley

Sarin - Wikipedija, prosta enciklopedija

Streptococcus pneumoniae

Vinca alkaloid

Positron emission tomography

Sensitization

Ebola

Pre-Bötzinger complex

GABRA4

Acne

Rituximab

Aluminijum arsenid - Википедија

Códigos de classificação JEL - Wikipédia, a enciclopédia livre

Theanine - Simple English Wikipedia, the free encyclopedia

Substance P

Template:Infobox tin

Rituximab

Oxazoline

Metanefrin

Alcoholic drink

Levothyroxine

Compounds1

• Look around you… each product that we use is a product of chemical compounds or an intermediate. (uprm.edu)

Biomolecular Engineering1

• He then moved to the Chemical and Biomolecular Engineering department at the University of Illinois at Urbana-Champaign, where he obtained his Ph.D. under the tutelage of Prof. Huimin Zhao developing cooperative one-pot chemoenzymatic reactions. (ufl.edu)

Catalysis1

• The meeting captivated a vicinity of utilitarian discussions on novel subjects like Advances in Catalysis, Chemical Reaction Engineering, Environmental Catalysis and Nano Catalysis, Biocatalysis, Biotransformation and Organocatalysis, Photochemistry, Photobiology and Electrochemistry, to mention a few. (magnusgroup.org)

Engineering16

• Chemical Engineering combines three basic physical sciences: chemistry, physics and biology, alongside mathematics, and applies them to the design, analysis, and control of chemical, physical and biological processes, including a risks assessment of them. (uprm.edu)
• Which products surround you as a result of Chemical Engineering work? (uprm.edu)
• Pursuing a Chemical Engineering Bachelor at UPRM takes five years. (uprm.edu)
• Yet, Chemical Engineering students differ, since their curriculum is also oriented towards a strong preparation in chemistry fundamentals during the first years. (uprm.edu)
• If you have these qualities, you should consider Chemical Engineering as your profession of choice. (uprm.edu)
• The Department of Chemical Engineering proudly welcomes three new faculty members. (ufl.edu)
• He emigrated to the U.S. where he received his B.S. degree in Chemical Engineering from North Carolina State University. (ufl.edu)
• Mérida is a recent graduate of the University of Puerto Rico, Mayagüez Chemical Engineering Ph.D. program. (ufl.edu)
• His current teaching interests include Unit Operations, Bioprocess Engineering, and nanoparticle-based Drug Delivery. (ufl.edu)
• The BS in Chemical Engineering is accredited by the Engineering Accreditation Commission of ABET, http://www.abet.org. (sdsmt.edu)
• Chemical engineering deals with the design and development of procedures to create products - products like food and fuel. (sdsmt.edu)
• With a degree in chemical engineering from South Dakota Mines, you can work in jobs that increase crop yields to combat world hunger, create new materials, reduce pollution, and meet energy demands. (sdsmt.edu)
• Chemical engineers are in high demand, especially chemical engineering graduates from South Dakota Mines. (sdsmt.edu)
• The average starting salary for a Mines chemical engineering graduate is $69,848. (sdsmt.edu)
• South Dakota Mines chemical engineering grades are in high demand due to the large number of industries that depend on the synthesis and processing of chemicals and materials. (sdsmt.edu)
• As a chemical engineering major at South Dakota Mines, you don't have to wait to participate in research. (sdsmt.edu)

Mold1

• There is not a fitted mold of qualities to become a Chemical Engineer, however, the above mentioned characteristics could indicate a potential successful candidate in this career. (uprm.edu)

Chemistry1

• They do this by applying the principles of chemistry, biology, physics, and math to solve the problems that occur during the production of chemicals, fuel, drugs, food, and a myriad of other products. (sdsmt.edu)

Physical1

• There are physical phenomenon fundamentals that are important to Chemical Engineers as they develop and implement them in chemical processes. (uprm.edu)

Engineers8

• Chemical engineers discover, develop and implement creative solutions to current world problems in order to benefit humankind. (uprm.edu)
• In a simpler way, Chemical engineers transform raw matter or chemicals into a more valuable and useful products. (uprm.edu)
• Chemical engineers lead to larger scales what the chemists elaborate on a laboratory in much smaller scales. (uprm.edu)
• Once a potential product is identified, chemical engineers verify if it can be produced on larger scales, which is the efficiency and at what pressure and temperature conditions can be done, etc. (uprm.edu)
• Who are good Chemical Engineers? (uprm.edu)
• Design engineers formulate the equipment and plant specifications in order to implement the desired chemical process, it also evaluates its construction and startup. (uprm.edu)
• Chemical engineers take raw materials and create every day, usable products. (sdsmt.edu)
• Chemical engineers (and biological engineers) are instrumental in creating pharmaceuticals and lifesaving devices such as the artificial kidney. (sdsmt.edu)

Toxicity15

• Whereas historically drugs such as heroin and cocaine have been considered the "dangerous" drugs, in recent years, prescription drug abuse has far surpassed "illegal" drugs as agents of lethal drug toxicity. (medscape.com)
• Alcohol Interactions with Drugs and Chemicals is a concise volume that identifies, documents, and assesses the capacity of alcohol to alter the toxicity of chemical pollutants and drugs in animal models and humans. (routledge.com)
• Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a drug, reaction to a drug or drug abuse. (medindia.net)
• We provide an overview of computational systems biology approaches as applied to the study of chemical- and drug-induced toxicity. (frontiersin.org)
• We describe three case studies of complementary multi-scale computational modeling approaches to understand perturbation of toxicity pathways in the human liver as a result of exposure to environmental contaminants and specific drugs. (frontiersin.org)
• Central to this vision is the idea of "toxicity pathways" - innate cellular signaling pathways that are perturbed by chemicals and pharmaceuticals, and the determination of chemical concentration ranges where those perturbations are likely to be excessive, thereby leading to adverse health effects if present for a prolonged duration in an organism. (frontiersin.org)
• In 2009, the U.S. Environmental Protection Agency published its Strategic Plan for Evaluating the Toxicity of Chemicals ( U.S.EPA, 2009 ), which also envisions dynamic mathematical modeling as a key component of risk assessment linking toxicity pathways to dose-response. (frontiersin.org)
• Derivatives of lumiracoxib were synthesised to understand the contribution of different chemical groups to toxicity. (phys.org)
• Changes to compound stability (via formation of oxidised products, -OH), chemical reactivity, and metabolite formation were observed and they allude to the mechanism for causing toxicity. (phys.org)
• A research team led by Prof HO Han Kiat from the Department of Pharmacy, NUS has discovered the mechanisms involved when minor chemical modifications such as a single substitution of a small halogen or alkyl group (functional groups in chemical structures) of pharmaceutical drugs alters the toxicity profile of the drugs. (phys.org)
• By understanding the specific mechanisms contributing to the toxicity, pharmaceutical scientists can modify the chemical structure so as to develop drugs which are more effective and safe. (phys.org)
• As part of the research, the team used a pair of anti-inflammatory drugs, diclofenac and lumiracoxib, that differ minimally in terms of structure, but exhibit profound differences in terms of toxicity. (phys.org)
• Many other compounds with small chemical changes were also synthesised and evaluated for their potential to cause toxicity and how they may be metabolised differently in liver cells. (phys.org)
• Structure-toxicity relationship and structure-activity relationship study of 2-phenylaminophenylacetic acid derived compounds, Food and Chemical Toxicology (2014). (phys.org)
• The new tests use cell cultures rather than animals to establish the toxicity of cancer drugs and identify contaminated drugs. (timeshighereducation.com)

20195

• David Paul Lambert was sentenced to eight years and two months in prison at the start of 2019 on numerous offences including possession of a range of dangerous drugs. (gympietimes.com.au)
• Global Antibacterial Drugs Market 2015-2019 is a new research report added by Sandlerresearch.org under the Pharmaceutical category. (pitchengine.com)
• The analysts forecast global antibacterial drugs market to grow at a CAGR of 1.06% over the period 2014-2019. (pitchengine.com)
• This report covers present scenario and growth prospects of the global antibacterial drugs market for 2015-2019. (pitchengine.com)
• The report, Global Antibacterial Drugs Market 2015-2019 , has been prepared based on an in-depth market analysis with inputs from industry experts. (pitchengine.com)

Alcohol11

• Several medical examiners' offices that routinely test for alcohol and drugs of abuse report finding some substance on toxicologic analysis in at least 50% of their cases. (medscape.com)
• Alcohol Interactions with Drugs and Chemicals will be a valuable reference tool for environmental scientists, toxicologists, epidemiologists, and alcohol researchers studying the interactions of alcohol with drugs and chemical pollutants. (routledge.com)
• Alcohol and other drug abuse is estimated to cost the nation over $160 billion per year in lost productivity, health care costs, and crime. (druglibrary.org)
• There are constant reminders in the news media of the ever-present effects of alcohol and other drug abuse. (druglibrary.org)
• Health care professionals witness the effects of alcohol and other drug use on the health of the population every day. (druglibrary.org)
• Outpatient alcohol and drug treatment serving Crow Wing County and surrounding areas. (brainerd.com)
• Alcohol is a Drug? (bradfordhealth.com)
• As the most widely used and accepted drug, alcohol has wrecked havoc on millions of families. (bradfordhealth.com)
• Millions of people affected by drugs and alcohol continue to endure the damages of addiction because they don't think they can afford to get help. (bradfordhealth.com)
• SB-1247 Vessels: operation under the influence of alcohol or drugs: chemical testing. (ca.gov)
• They have a four times higher rate of drug, drug and alcohol abuse. (coursera.org)

Researchers16

• Researchers at the University of Warwick found that when the chemical, Sodium Formate, is used in combination with a metal-based cancer treatment it can greatly increase its ability to shut down cancer cells. (eurekalert.org)
• The Warwick researchers developed a novel method for binding Sodium Formate with JS07 to form a more potent form of the drug. (eurekalert.org)
• The discovery also allows the researchers to make variations of the psammaplin A chemical and to use these variants to further understand the anti-cancer activity of this natural product. (earthtimes.org)
• Researchers have been looking at the effects of drugs on fish over the course of several years, and the results show evidence that the drugs humans use are harming fish. (aquasana.com)
• Swedish researchers tested an anti-anxiety drug called oxazepam (found in water sources) on perch in the lab. (aquasana.com)
• Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment - called environmental estrogens - can produce infertility , abnormal reproductive development, including "precocious puberty ," and promote breast cancer. (medicalnewstoday.com)
• They found that by combining data about structural disturbances from many structures with activity profiles of their ligands (the estrogenic chemicals), researchers can identify the sub-ångström details that determine endocrine disruption. (medicalnewstoday.com)
• Researchers at the University of North Carolina began testing soaps after local nurses noticed an unusual uptick in positive drug tests on infants. (rawstory.com)
• Researchers added that less than 0.1 mililiters of these chemicals in a drug test sample could contaminate the results. (rawstory.com)
• To overcome this hurdle, researchers at University of California, San Diego School of Medicine have developed a way to chemically disguise RNAi drugs so that they are able to enter cells. (healthcanal.com)
• First, researchers generate RNAi drugs with a sequence that corresponds to the gene blueprint for the disease protein and then delivers them into cells. (healthcanal.com)
• That problem in the brain may be corrected by low doses of drugs used to treat anxiety and epileptic seizures, researchers from the University of Washington say. (medicaldaily.com)
• As the researchers call for immediate clinical trials, Astra-Zeneca has begun testing benzodiazepines and newer such drugs on people with autism. (medicaldaily.com)
• A study just published in the journal Substance Use & Misuse by researchers affiliated with New York University's Center for Drug Use and HIV Research (CDUHR), examined a national sample of high school seniors to determine who is currently at high risk for ecstasy use. (bio-medicine.org)
• Results suggest that while there are many important sociodemographic factors associated with ecstasy use, the researchers note that prevention of other drug use may be the most important factor in preventing ecstasy use, in part, because use of other drugs appears to override protective effects of certain characteristics. (bio-medicine.org)
• Given the positive expectations of experiences many adolescents associate with ecstasy, the researchers say that prevention efforts should focus on educating adolescents and young adults at highest risk with regard to the potential harmful effects of ecstasy, and just as importantly, education needs to continue to focus on preventing use of drugs that normally precede ecstasy use. (bio-medicine.org)

Dependency5

• A battle with chemical dependency may feel hopeless, but there is help available! (brainerd.com)
• The Brainerd Lakes Area is home to several programs for rehabilitation and chemical dependency care including medical care, counseling, and in patient treatment program. (brainerd.com)
• The chemical dependency team and addiction recovery services at Essentia Health-St. Joseph's Medical. (brainerd.com)
• Several relapse warning signs appear before you fall completely back into chemical dependency. (bradfordhealth.com)
• Chemical dependency is a mental, emotional, physical and spiritual problem and must be treated as such for successful recovery. (drug-rehab-center-hotline.com)

Intermediates2

• The chemical industry is already accustomed to tight controls over the smaller-volume domestic trade in pharmaceutical precursors, or chemical intermediates. (joc.com)
• It has been used to synthesize Musk 105 , 10-hydroxy-2-decylenic acid (queen acid) , as the intermediates of new drug for resistance to senile dementia -idebenone, and other medicine ,etc. (alibaba.com)

Psychotropic drugs2

• While others have envisioned a causal role for psychotropic drugs in idiopathic autism, we were astonished to find evidence that this might occur at very low dosages, such as those found in aquatic systems," said lead scientist Dr Michael Thomas. (prisonplanet.com)
• The Waynesville Police Department receives about a dozen calls a week related to synthetic drugs, which in essence are plants that have been sprayed with a number of unknown chemicals and psychotropic drugs, Hollingsed said. (smokymountainnews.com)

Pharmaceuticals3

• The congressional subcommittee's list includes chemical precursors, such as ephedrine and pseudoephedrine, which are used widely to make non- prescription pharmaceuticals. (joc.com)
• Chemicals in pharmaceuticals such as anti-seizure medications and anti-depressants may also contribute, since they mimic estrogen. (aquasana.com)
• Drugs and Pharmaceuticals: Safety Considerations. (wiley.com)

Exposure8

• Given their ubiquitous existence in the environment and our consumer products, it is challenging to entirely avoid exposures to these chemicals, although choosing products that are free of PFAS can help reduce the exposure," Sun said. (drugs.com)
• 4) Drug exposure to the nursing infant may be minimized by having the mother take the medication just after she has breast-fed the infant and/or just before the infant is due to have a lengthy sleep period. (aappublications.org)
• The new research shows how high-resolution imaging techniques could give scientists a window into how exposure to these chemicals may impact public health. (medicalnewstoday.com)
• Exposure to a wide variety of chemicals and drugs has become common in industrial, laboratory, and even household environments. (wiley.com)
• Drug and Chemical Toxicology is a quarterly peer-reviewed medical journal that publishes full-length research papers, review articles, and short communications that encompass a broad spectrum of toxicological data surrounding risk assessment and harmful exposure. (wikipedia.org)
• Edward was diagnosed as suffering from severe Aplastic Anaemia in April 1986 following exposure to a number of toxic chemicals at his workplace and, although it was not recognised by us at the time, he also suffered several of the documented symptoms of chemical poisoning (memory loss, jaundice, extreme fatigue etc.) in the weeks and months before diagnosis. (whale.to)
• During our investigations it became increasingly obvious that serious and often fatal blood disorders resulting from exposure to drugs, chemicals and radiation - with implications that these conditions are pre-cancerous - could often be avoided with public awareness. (whale.to)
• Such drugs when combined with the clinically approved drugs, would give a wider set of drugs to tackle MEN2, a second line of defence if/when patient relapse occurs and it would allow more diverse approaches for MEN2 treatment involving drug holidays, where short exposure to varying types of RET inhibitors, reduce the opportunity for drug resistance arising. (amend.org.uk)

Molecular7

• Nettles and his colleagues reasoned that they could use a similar approach with x-ray crystallography to compare molecular snapshots, or structures, and better understand how estrogenic chemicals control receptor activity. (medicalnewstoday.com)
• Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel," Molecular Cancer Therapeutics , vol. 5, no. 4, pp. 853-867, 2006. (hindawi.com)
• Many current approaches use nanoparticles to deliver RNAi drugs into cells," said Steven F. Dowdy, PhD, professor in the Department of Cellular and Molecular Medicine and the study's principal investigator. (healthcanal.com)
• While nanotechnology protects the RNAi drug, from a molecular perspective nanoparticles are huge, some 5,000 times larger than the RNAi drug itself. (healthcanal.com)
• As for the solving of this task, it may be reached only in the case of successful fundamental studies of mechanisms of toxic action of different classes of chemicals performed at different biological levels (systemic, organ/tissue, cellular and molecular levels of research). (biomedsearch.com)
• By analyzing the correlation patterns between GPCRs and ligands, we can gain more detailed knowledge about their conserved molecular recognition patterns and improve drug design efforts by focusing on inferred candidates for GPCR-specific drugs. (biomedsearch.com)
• Jeremy Smith, Governor's Chair for Molecular Biophysics at the University of Tennessee, Knoxville, and director of the Center for Molecular Biophysics at Oak Ridge National Laboratory, has worked with a research team from the UT Health Science Center to discover a chemical compound that could lower sugar levels as effectively as the diabetes drug metformin but with a lower dose. (medicalxpress.com)

Substance5

• This category lists articles that have a second identifier in {{Infobox drug}} , introducing a second chemical substance. (wikipedia.org)
• Mix drugs with an undesirable substance, such as cat litter or used coffee grounds. (aquasana.com)
• And [two], standard drug tests provide society with very little useful information regarding whether someone actually used a particular substance, when they last used a particular substance, or whether they were impaired at the time they were tested. (rawstory.com)
• The way the drugs are made and sold one can never be sure what type of chemicals the substance contains, he added. (smokymountainnews.com)
• The police receive calls either when parents find the substance among their children's possessions or a child has grown suddenly violent or passed out as a result of ingesting synthetic drugs. (smokymountainnews.com)

Pathways4

• CRISPR/Cas9-based screens, which are largely limited to a gene's loss of function, have already been very successful in identifying drug targets and pathways related to the drug's mode of action. (nih.gov)
• After exposing fish to two different anti-depressant drugs, Prozac and venlafaxine, and a seizure-controlling drug called carbamazepine, experts from the University of Idaho were 'astonished' after observing changes in the genetic pathways of the fish. (prisonplanet.com)
• Some adverse events are predictable consequences of the known mechanism of a drug, but others are not predicted and seem to result from 'off-target' pathways. (pubmedcentralcanada.ca)
• It is not surprising that evolutionary relationships might lead to shared drug-binding capabilities in protein paralogs found across a wide range of cell types and biological pathways. (pubmedcentralcanada.ca)

Compound7

• Developed by Warwick's Department of Chemistry, the drug, a compound of the metal ruthenium called JS07, is capable of exploiting a cancer cell's natural weaknesses and disrupts its energy generation mechanism. (eurekalert.org)
• Innovative drug is defined as a chemical compound with new and clearly defined structure, pharmacological property(ies) and apparent clinical value. (lexology.com)
• In a study published online Dec. 3 in the Journal of Pharmacology and Experimental Therapeutics, scientists from the University of Michigan report that a compound called benzodiazepine-423 (Bz-423)---a chemical cousin of the anti-anxiety drugs Valiumâ and Xanaxâ---suppresses cell growth in a model of psoriasis. (innovations-report.com)
• However, there is no way to know the exact chemical make-up of a compound unless it is tested. (smokymountainnews.com)
• To compound the problem, protein-ligand studies have found that a single drug can bind targets with vastly different pharmacology and that about 35% of known drugs have two or more targets [ 5 ]. (pubmedcentralcanada.ca)
• Chemical compound shows promise as alternative to opioid pain. (bio-medicine.org)
• This chemical compound lowers sugar levels in mice as effectively as metformin, but with a 30-times lower dose," Smith said. (medicalxpress.com)

Toxic chemicals1

• Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. (aspetjournals.org)

Biological11

• Gary D. Strahan uses physico-chemical techniques to understand biological systems relevant to pharmaceutical discovery and agricultural and natural product analyses. (wiley.com)
• Dr Fuchter points out that the new chemical routes toward the natural product psammaplin A were developed with the particular view to preparing diverse variants for biological assessment. (earthtimes.org)
• Glycol chitosan (GC) and its derivatives have been extensively investigated as safe and effective drug delivery carriers because of their unique physiochemical and biological properties. (mdpi.com)
• It provides interaction data between GPCRs and their ligands, along with chemical information on the ligands, as well as biological information regarding GPCRs. (biomedsearch.com)
• These data are connected with each other in a relational database, allowing users in the field of Chemical Genomics research to easily retrieve such information from either biological or chemical starting points. (biomedsearch.com)
• The study, appearing in the Journal of Biological Chemistry , investigated how the drug nifurtimox works to kill off the trypanosome. (qmul.ac.uk)
• Co-author of the study, Dr Shane Wilkinson from Queen Mary's School of Biological and Chemical Sciences, said: "Hopefully our research will lead to the development of anti-parasitic medicines which have fewer side effects than Nifurtimox and are more effective. (qmul.ac.uk)
• Dr Wilkinson and his colleagues Dr Belinda Hall and Mr Christopher Bot from Queen Mary's School of Biological and Chemical Sciences focused their research on the characterisation of the breakdown product from nifurtimox. (qmul.ac.uk)
• With the increasing prevalence of drug-resistant parasites, considerable interest now exists in the identification of new biological targets for the development of new malaria chemotherapeutics. (upenn.edu)
• Se SVT Västnytts inslag om Vinnova-projektet "Challenge-driven innovation - Next generation´s test system for faster and more secure biological evaluation of drugs, materials and chemicals" som Acreo deltar i. (acreo.se)
• Some criminologists argue that the appearance of a lower recidivism rate in male sex offenders who take chemical castration treatment than in those who do not can be explained by factors other than biological effects of the medication. (wikipedia.org)

Humans3

• Like other animal model research, scientists theorize that unwanted drugs getting into our water supplies may also have negative health effects on humans, but without extensive studies, this is conjecture. (aquasana.com)
• Finally, because the stereochemistry of the principal metabolite of cimetidine and (S)-nicotine in small experimental animals is distinct from that observed in humans, it is likely that species variation in predominant FMO isoforms exist and this may have important consequences for the choice of experimental animals in human preclinical drug design and development programs. (nih.gov)
• Thus, the results presented in this study provide useful information for the study of drug biotransformation in humans and for the basis of drug toxicities, carcinogenesis and teratogenesis. (aspetjournals.org)

Approaches2

• This chemogenomic approach combined with latest sequencing technologies allows deconvolution of drug targets and characterization of drug-target binding interfaces at amino acid resolution, therefore nicely complementing existing biochemical approaches. (nih.gov)
• drugs chemicals and approaches? (windhover.org)

Fine chemicals1

• We're a professional manufacturer of fine chemicals, a premium aerospace supplier, with 47 years history and 5 R&D bases. (alibaba.com)

Imbalance4

• This book overturns the idea that psychiatric drugs work by correcting chemical imbalance and analyzes the professional, commercial and political vested interests that have shaped this view. (palgrave.com)
• New research gives hope to soon treating the "chemical imbalance" underlying autism spectrum disorder. (medicaldaily.com)
• The biology of autism spectrum disorder may be as simple as the "chemical imbalance" illustrated by cartoon blobs in Pfizer's classic 2002 commercial spot for Zoloft. (medicaldaily.com)
• After repeated use of addictive drugs it is progressively more difficult for the neurotransmitters to recover after the drugs wear off, which eventually creates a chemical imbalance in the brain. (drug-rehab-center-hotline.com)

Metabolites4

• Pharmaceutical drugs are broken down by enzymes in the liver into their metabolites, which are subsequently excreted in the faeces and urine. (phys.org)
• In conjunction with asymmetric chemical syntheses and spectral, chiroptical, chromatographic and stereochemical correlation methods, we have developed procedures for the quantification of sulfoxide enantiomers and tertiary amine N-oxide diastereomer metabolites arising from the action of the adult human liver and other flavin-containing monooxygenases (FMOs). (nih.gov)
• through a chemical process the liver breaks the drug down into by-products called metabolites. (drug-rehab-center-hotline.com)
• The fat tissue acts as a sponge to absorb the dangerous drug metabolites then slowly releases them back into the blood stream where they begin the process to be re-metabolized. (drug-rehab-center-hotline.com)

Urine4

• urine is the primary body fluid used for drug screening. (medscape.com)
• Our bodies absorb some of the drugs we take, but residual amounts pass through us (in our urine or stool) and are flushed down the toilet, although these amounts are very small in comparison. (aquasana.com)
• In other words, it would not be surprising to find trace amounts of these products in urine, saliva or hair follicles - putting a huge question mark on the validity of less expensive drug tests conducted by employers and law enforcement agencies around the nation. (rawstory.com)
• Only in an environment of criminal drug prohibition can people judged solely on the contents of their urine, rather than on their behavior and performance. (rawstory.com)

Discovery7

• This research method could also be used to speed up the discovery of new drugs for breast cancer and many other diseases, added study senior author Kendall Nettles, associate professor at TSRI. (medicalnewstoday.com)
• Drugs: Discovery and Development. (wiley.com)
• But the real excitement of the discovery is the potential impact on a large class of peptide drugs, Gellman says. (healthcanal.com)
• GLIDA: GPCR--ligand database for chemical genomics drug discovery--database and tools update. (biomedsearch.com)
• We hope that it will prove very useful for Chemical Genomics research and GPCR-related drug discovery. (biomedsearch.com)
• This new approach to diabetes drug discovery has been published in PLOS One , a peer-reviewed open access scientific journal. (medicalxpress.com)
• My own attitude is one of cautious optimism, which in drug discovery is usually the best you can have. (fieldofscience.com)

Reactivity3

• They specifically highlighted the ingredients polyquaternium 11 and cocamidopropyl betaine as "showing strong reactivity" with chemicals in less expensive drug tests, producing the positive result for marijuana. (rawstory.com)
• The chemical reactivity of as-anodized porous silicon is shown to have an adverse effect on a model drug (Lansoprazole) loaded into the pores. (springer.com)
• Sailor MJ (2014) Chemical reactivity and surface chemistry of porous silicon. (springer.com)

Reactions10

• the study of the rates of chemical reactions. (drugs.com)
• In their paper, the UCR chemists discuss a set of chemical reactions involving the use of catalysts other than those that are CAAC-based. (redorbit.com)
• All of this can dramatically reduce the cost of manufacturing drugs, given that pharmaceutical companies are increasingly using carbene-supported catalysts for their chemical reactions. (redorbit.com)
• Now it mostly appears when it's unintentionally produced from chemical reactions at industrial sites. (healthline.com)
• Experts from the University of Nottingham have created a self-sustaining circuit of reactions which is a greener and more efficient method of chemical production. (nottingham.ac.uk)
• In their paper Self-sustaining closed-loop multienzyme mediated conversion of amines into alcohols in continuous reactions , published in Nature Catalysis , Drs Francesca Paradisi and Martina Contente of the University of Nottingham produce chemicals more efficiently through a looped set of reactions using enzymes in flow. (nottingham.ac.uk)
• Dr Paradisi, Associate Professor in Biocatalysis and Enzyme Engineering in the School of Chemistry, explained that water is often used as the medium in which enzyme mediated chemical reactions can take place but there is an issue in disposing of the waste at the end of the process. (nottingham.ac.uk)
• We also discovered that working in this way meant the yields of some "tricky to make" high-value products are also much higher than for traditional chemical reactions - by over 20-fold. (nottingham.ac.uk)
• For example, highly publicized cases of severe adverse reactions recently resulted in a US Food and Drug Administration advisory panel suggesting that the popular pain relievers Percocet and Vicodin be banned [ 2 ]. (pubmedcentralcanada.ca)
• Royalty free and rights managed images of allergic reactions of drugs and other chemicals. (sciencephoto.com)

Diseases7

• The drug, a small molecule called TAK-935, inhibits the enzyme cholesterol 24-hydroxylase, which may have a role in central nervous system diseases such as epilepsy. (acs.org)
• Drugs and Human Diseases. (wiley.com)
• Also, these chemicals may be industrial hazards promoting the origin and development of various occupational diseases. (biomedsearch.com)
• At present, resistance to the drugs used in the treatment of many infectious diseases is increasing, while microbial infections are being found to be responsible for more life threatening diseases than previously thought. (ijpsonline.com)
• Many myths, theories, and speculations exist as to the exact etiology of the diseases, drugs, and chemicals that affected the creativity and productivity of famous sculptors, classic painters, classic music composers, and authors. (healthyplace.com)
• Diseases, drugs, and chemicals may have influenced their creativity and productivity. (healthyplace.com)
• To calculate the market size, the report considers revenue generated from the sales of various prescription drugs along with the generic drugs used for the treatment of various infectious diseases caused by the different strains of bacteria. (pitchengine.com)

Antiviral1

• Foscarnet sodium is an antiviral drug for the treatment of CMV retinitis, currently in the form of twice-weekly intravitreal injection. (rsc.org)

Development9

• We are confident that our results will lead to the development of a new, highly selective generation of Alzheimer's drugs," explained Demuth. (eurekalert.org)
• Click chemistry for drug development and diverse chemical-biology applications. (nih.gov)
• This change may incentivize multinational companies wishing to bring innovative drugs to China to start their product development in China earlier in the process than before in order to realize marketing advantages. (lexology.com)
• Among these, cyanobactins have sparked attention due to their interesting bioactivities and for their potential to be prospective candidates in the development of drugs. (mdpi.com)
• The combination of drugs with external devices to control light may contribute to the development of personalized medicine in which treatments can be adapted to each patient, limiting the time given regions are treated, thus markedly reducing unwanted effects. (nanowerk.com)
• It therefore is a good starting point for the development of a new and effective drug to fight diabetes. (medicalxpress.com)
• our biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and chemical manufacturing. (eindiabusiness.com)
• My work presented here focuses on the development and use of chemical tools to study malarial proteases, a class of enzymes that have been shown to play essential roles throughout the parasite lifecycle, but the majority of which though are still uncharacterized. (upenn.edu)
• This drug resistance arises because the cancer cells mutate to shrug off the effectiveness of the anti-cancer drug, in an analogous process to the development of antibiotic resistance in bacteria. (amend.org.uk)

Prevalence4

• The prevalence of drug use is reiterated here to emphasize the vital role that toxicologic analysis plays in autopsy pathology. (medscape.com)
• Although the incidence of false-positive results is low, such tests are less reliable when the prevalence of drug abuse is also low. (druglibrary.org)
• To rid the workplace of drugs, the prevalence of drug abuse needs to be known as well as whether, in fact, such abuse is directly related to workplace outcomes, such as productivity, safety, and product integrity. (druglibrary.org)
• While such reports tend to emphasize the seriousness of the drug abuse problem, they do not actually estimate the prevalence of drug use in the workplace. (druglibrary.org)

Biology5

• The study was published online ahead of print in the journal Cell Chemical Biology . (medicalnewstoday.com)
• Pathway mapping and modeling based on network biology concepts are a key component of the vision laid out in this report for a more biologically based analysis of dose-response behavior and the safety of chemicals and drugs. (frontiersin.org)
• Chemical systems biology, or the application of systemwide tools to the analysis of pharmacological responses, can help address the lack of efficacy and undesired off-target effects [ 3 ]. (pubmedcentralcanada.ca)
• 7 ]) have used a chemical systems biology approach to explain the serious side-effects of a drug that was being trialed for prevention of cardiovascular disease. (pubmedcentralcanada.ca)
• Dr. Devi and her team are currently working with co-author Marta Filizola, PhD, Associate Professor of Structural and Chemical Biology at Mount Sinai, to learn how CYM51010 binds to the protein complex. (bio-medicine.org)

Interaction3

• Masamichi Tsuboi studies DNA and RNA structures, drug-DNA interaction, protein conformation, protein-nucleic acid recognition, and virus structure using a variety of physicochemical and biomedical techniques including X-ray diffraction, UV-Visible, IR/Raman , and NMR spectroscopy. (wiley.com)
• By inducing single nucleotide changes using an alkylating reagent, it is possible to generate amino acid changes that perturb the interaction between a drug and its direct target, resulting in drug resistance. (nih.gov)
• The number of confident predictions grows faster than the number of known structures, suggesting that this approach will play a key role in completing the protein-chemical interaction repertoire. (plos.org)

Chemotherapy4

• Cancers that respond to the administration of this drug as part of a controlled chemotherapy regimen are Hodgkins Lymphoma, non-small cell lung cancer, head and neck cancer, breast cancer, and testicular cancer. (enotes.com)
• Vinblastine has several interesting chemical properties in it's application as a chemotherapy drug regimen. (enotes.com)
• The benefit to society, of course, would be that vinblastine is an effective chemotherapy drug, one that helps eradicate cancer cells by destroying the formation of those cancer cells within the confines of their reproductive cell cycle. (enotes.com)
• One of the tests is designed to assist the dosage of some highly toxic drugs used in chemotherapy for cancer, a disease which causes almost a million deaths in the EU every year. (timeshighereducation.com)

Adverse4

• Chemical modifications can cause the drug to have both beneficial and adverse effects on patients. (phys.org)
• Drug-related adverse events affect approximately 2 million patients in the United States each year, resulting in about 100,000 deaths [ 1 ]. (pubmedcentralcanada.ca)
• The laboratory assays currently used to evaluate potential adverse drug effects can be costly and time-consuming. (pubmedcentralcanada.ca)
• The research recorded a continuation of this more positive behaviour after the administration of the drug had ended with no evidence of adverse side effects and recommended medroxyprogesterone acetate along with counselling as a successful method of treatment for serial sex offenders. (wikipedia.org)

Manufacture1

• Interestingly, psammaplin A and our man-made variants show high selectivity in lab-based experiments, which is an important feature for the design and manufacture of future drugs. (earthtimes.org)

Proteins5

• The basic premise is that two proteins sharing a common bound chemical will likely share others. (plos.org)
• We show for a benchmark that known protein-chemical structures are reconstructed with good accuracy and sometimes via very different proteins and chemicals. (plos.org)
• We exploited the basic premise that if two proteins in the network share one bound chemical they are likely to share others. (plos.org)
• A single prediction candidate ( Figure 1 ) involves combining three protein-chemical complex structures, two of which involve two distinct proteins (P 1 and P 2 ) binding a common ligand (L a ) and a third where one protein (P 1 ) binds another ligand (L b ). (plos.org)
• Traditionally, the oral route cannot be employed for the delivery of macromolecular drugs such as proteins and peptides due, in large part, to limited transport across the epithelial membrane. (springer.com)

Pharmaceutical drugs1

• NUS pharmaceutical scientists have discovered the mechanisms involved when small chemical modifications to certain pharmaceutical drugs may cause harm instead of improving treatment. (phys.org)

Search2

• The indexer can also go to the MeSH Browser, type the name of the chemical, and search for the exact term. (nih.gov)
• Our approach could prove crucial to stimulate the search for a second and third generation of improved drugs to treat MEN2 disease and to help benefit patients. (amend.org.uk)

Treatment12

• In cities and towns that use wastewater treatment plants, prescription and over-the-counter drugs are poured down the sink or flushed down the toilet, pass through the treatment system, and then may enter rivers and lakes. (aquasana.com)
• Drug-Rehab.org will place you in contact with a trained advisor from one of our sponsoring treatment providers. (drug-rehab.org)
• It is a concise, powerful, well-referenced and well-constructed critique of psychiatric drug treatment. (palgrave.com)
• This means that these drugs, modified to enhance treatment, may instead be undesirable for the patient. (phys.org)
• Vinblastine is an antimicrotubule drug used in the treatment of various kinds of cancer. (enotes.com)
• These are very exciting results because they suggest that existing drugs - called benzodiazepines - might be useful in treatment of the core deficits in autism," senior study leader William Catterall said in a statement . (medicaldaily.com)
• drugs chemicals for' seller' in Psycholinguistic treatment. (windhover.org)
• Metformin, a drug that lowers the liver's production of sugar and decreases risk of mortality, is currently recommended as a first-line treatment. (medicalxpress.com)
• Eventually the drug user is completely addicted and it becomes nearly impossible to stop taking the drugs without a comprehensive treatment program. (drug-rehab-center-hotline.com)
• These types of treatment programs begin treatment with a holistic detox that help cleans the body of drug deposits accumulated in the fat cells. (drug-rehab-center-hotline.com)
• Chemical castration is generally considered reversible when treatment is discontinued, although permanent effects in body chemistry can sometimes be seen, as in the case of bone density loss increasing with length of use of DMPA. (wikipedia.org)
• One hypothesis is that men who accept the negative effects of hormonal treatment in exchange for shorter prison sentence are distinct in that they value freedom from incarceration higher than men who rather stay in prison for a longer time than face the side effects of chemical castration. (wikipedia.org)

Resistance1

• A recent review by Giordano and Petrelli, for example, describes their approach to developing multi-target drugs for cancer therapy while avoiding drug resistance by targeting multiple tyrosine kinase receptors [ 6 ]. (pubmedcentralcanada.ca)

Found13

• MeSH contains thousands of chemicals, so it is likely that the specific chemical in a given article can be found by searching the MeSH Browser. (nih.gov)
• For example, the drug Propranolol can be readily found using either method. (nih.gov)
• The Introduction and Epidemiology sections have both mentioned that drugs are found in 50% of forensic autopsies (when tested) and that drugs or medications are responsible for causing or contributing to death in over 20% of deaths unrelated to natural causes in the United States. (medscape.com)
• The study can't prove cause-and-effect, but "found that individuals with higher blood levels of these chemicals had more difficulties of maintaining weight loss after dieting," said study lead author Dr. Qi Sun. "This pattern is primarily observed in women. (drugs.com)
• A report in a recent edition of Organic & Biomolecular Chemistry , the journal of the Royal Society of Chemistry, described how a young scientist from Imperial College London had been awarded a grant of £106,079 to investigate naturally occurring chemicals found in sea sponges in an effort to find out more about anti-cancer drugs. (earthtimes.org)
• More detailed information on specific chemicals and families of chemicals can be found in their respective articles. (drugs-forum.com)
• They found that just traces of common medications and other chemicals in the water were enough to bring about autism. (prisonplanet.com)
• There, Dowdy's team found that siRNNs were significantly more effective at blocking target protein production than typical RNAi drugs - demonstrating that once siRNNs get inside a cell they can do a better job. (healthcanal.com)
• Studies found that the effect of another brain chemical called glutamate, which when perturbed is thought to cause dyskinesias, was also inhibited through by this drug. (michaeljfox.org)
• Police, local radio RPP said, found drug making chemicals and supplies, including 620 kilograms of sulfuric acid, 720 kilograms of kerosene, 600 kilograms of formic acid, 100 kilograms of calcium oxide, and 10 kilograms of baking soda. (livinginperu.com)
• Smith's computations found several chemicals that might activate the protein, and the Quarles laboratory at UTHSC tested each. (medicalxpress.com)
• No clear sex-related differences in individual P-450 contents and drug- and carcinogen-metabolizing activities were detected in 60 human samples, except that P-450 1A2-dependent activities were found to be higher in mean than in women in the Caucasian population only. (aspetjournals.org)
• We delineated many important sociodemographic risk factors, but the most consistent and important risk factor we found is use of other drugs. (bio-medicine.org)

Laboratory1

• We are leading suppliers of laboratory chemicals, plastic wares, glass wares, instruments and equipments, in jaipur and rajasthan. (eindiabusiness.com)

Backbone3

• Unfortunately, due to their size and negatively charged chemical groups (phosphates) on their backbone, RNAi drugs are repelled by the cellular membrane and cannot be delivered into cells without a special delivery agent. (healthcanal.com)
• Potentially, the "alter-the-backbone" strategy could allow oral dosing of the rather fragile peptide drugs, which today must be injected to avoid destruction in the stomach and small intestine. (healthcanal.com)
• The backbone of nifurtimox contains a chemical group called a nitro linked to a ring structure called a furan," Dr Wilkinson explained. (qmul.ac.uk)

Castration6

• Late king of Pop Michael Jackson had a "chemical castration" drug to suppress his sexual urges towards under-age boys, if reports are to be believed. (medindia.net)
• Chemical castration is castration via anaphrodisiac drugs, whether to reduce libido and sexual activity, to treat cancer, or otherwise. (wikipedia.org)
• Unlike surgical castration, where the gonads are removed through an incision in the body, chemical castration does not remove organs, nor is it a form of sterilization. (wikipedia.org)
• The first use of chemical castration occurred in 1944, when diethylstilbestrol was used with the purpose of lowering men's testosterone. (wikipedia.org)
• Chemical castration is often seen as an easier alternative to life imprisonment or the death penalty because it allows the release of sex offenders while reducing or eliminating the chance that they reoffend. (wikipedia.org)
• These scientists explain apparently lower recidivism as an artifact of men who accept chemical castration being more engaged in hiding the evidence for reoffending, and that paroling such offenders constitute a risk of releasing criminals who commit as many new crimes as others but are better at hiding it. (wikipedia.org)

Peptide drugs1

• Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs. (springer.com)

Toxicology2

• Entire textbooks have been written on forensic toxicology and individual drugs and chemicals that can cause death. (medscape.com)
• He is also the editor of Toxicology of Pesticides in Animals, and author of Safety Evaluation of Environmental Chemicals. (wiley.com)

Liver2

• Smith, together with Jerome Baudry, of the University of Alabama at Huntsville, and graduate student Karan Kapoor, of the University of Illinois at Urbana-Champaign, used high-performance computing to create sophisticated simulations to suggest chemicals that could activate GPRC6A, a protein that regulates sugar levels by simultaneously correcting abnormalities in pancreatic insulin secretion, glucose uptake into skeletal muscle, and liver regulation of glucose and fat metabolism. (medicalxpress.com)
• There are three, 5 inch bottles labeled as follows: LIVER SPECIAL, CATARRH CHRONIC, and MERCURY PROTO IODIDE (the Mercury example mentions the Food and Drugs Act of 1906 on the label. (trocadero.com)

Harmful3

• A new drug candidate previously shown to reduce harmful side effects of the autoimmune disease lupus also may be useful in treating psoriasis. (innovations-report.com)
• The book explains the beneficial and harmful aspects of a broad range of materials to which students, trainees, skilled workers, managers, and personnel associated with regulatory agencies are exposed, with the purpose of helping them avoid the illnesses associated with the misuse of chemicals and drugs. (wiley.com)
• The drug detoxification is achieved through a strict regimen of vitamins, minerals and other natural supplements in combination with exercise, and a low temperature sauna which rids the body of the harmful drug residue. (drug-rehab-center-hotline.com)

Selective3

• The team's preliminary results indicate that these psammaplin A variants are more potent than the natural product and that they could well form the basis of new selective drugs in the future. (earthtimes.org)
• The sheer volume of trade in some of these chemicals, such as acetone, of which 4 billion pounds a year are produced by 10 major global companies, will complicate a reporting requirement that is not selective. (joc.com)
• Currently, the best treatments for skin lesions associated with psoriasis are topical steroids, but the problem with those drugs is that they're not selective for the disease-causing cells. (innovations-report.com)

Effects19

• Understand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. (wiley.com)
• Some of them produce effects similar to illegal drugs. (drugs-forum.com)
• Until we have conclusive studies analyzing the effects of unwanted drugs in our water, it is best to be safe and install a water filter. (aquasana.com)
• There are also protein drugs approved for use in treating psoriasis, but those drugs are injected instead of applied topically, which makes them more costly, less convenient and more likely to cause side effects since they are delivered throughout the body. (innovations-report.com)
• The Waynesville Police Department, in cooperation with residents, schools and other law enforcement agencies, has started hosting meetings around Haywood County to generate greater awareness of synthetic drugs and their side effects. (smokymountainnews.com)
• A study was commissioned to investigate the consequences of the use of BZP as a recreational drug but it was abandoned because of the unpleasant side effects reported by volunteers. (drugs-forum.com)
• it] is far from one-sided, and argues that rather than discarding drugs we should use them properly and concentrate on their effects rather than upon traditional but ultimately unscientific assumptions. (palgrave.com)
• Finally, the numerous side effects of multiple new drugs may serve as causes of a number of different health disorders. (biomedsearch.com)
• Informative guides on ecstasy, ecstasy effects, ecstasy pills, ecstasy dangers, ecstasy drug tests, mixing ecstasy with other drugs and the legality of ecstacy. (thegooddrugsguide.com)
• Learn the risks and effects of abusing inhaled chemicals. (thegooddrugsguide.com)
• Know the basics about ketamine, as well as understand ketamine effects, ketamine addiction, ketamine dangers, ketamine drug tests, and the results of ketamine mixing with other drugs. (thegooddrugsguide.com)
• Traditional drug design has relied heavily on the one drug-one target paradigm [ 3 ], but this may overlook system-wide effects that cause the drug to be unsuccessful. (pubmedcentralcanada.ca)
• A systems view of the body's responses to a drug threatens the simplicity of the one drug-one target paradigm, but could provide a framework for considering all effects, and not just those that are targeted. (pubmedcentralcanada.ca)
• The AUL model ensures that women considering a drug-induced abortion receives comprehensive information on abortion-inducing drugs, including the potential to reverse the effects of the drugs should she change her mind. (aul.org)
• This study will examine the effects of certain investigational anti-cancer drugs on the genetic and protein makeup of cells. (clinicaltrials.gov)
• and 2) predict which patients will have a greater chance of developing side effects or a greater chance of benefiting from the drug. (clinicaltrials.gov)
• A drug may be sterilised, but not necessarily free from all traces of bacteria and this can lead to side-effects such as fever, pain and shock. (timeshighereducation.com)
• Addictive drugs produce similar effects in the brain as the natural chemicals. (drug-rehab-center-hotline.com)
• All these side effects are extremely painful, and will usually drive a person to go back taking the very drugs that have caused the pain. (drug-rehab-center-hotline.com)

Scientists1

• Scientists have uncovered the mechanisms behind a drug used to treat African sleeping sickness and Chagas disease, infections caused by trypanosome parasites which result in 60,000 deaths each year. (qmul.ac.uk)

Structures2

• His work has emphasized spectroscopic methods, NMR, and computational modeling to determine the structures and properties of multistranded DNA, drug-DNA complexes, carbohydrates, and other biomolecules, as well as metabonomic and chemometric studies. (wiley.com)
• The aim of this review is to update the current knowledge of cyanobactins, recognized as being produced by cyanobacteria, and to emphasize their genetic clusters and chemical structures as well as their bioactivities, ecological roles and biotechnological potential. (mdpi.com)

Endogenous1

• Blood is also the way we get rid of waste products of cellular metabolism (endogenous toxins), and chemicals, drugs and toxins from exogenous sources. (totalhealthinstitute.com)

Widely2

• The Food and Drug Administration (FDA) announced it's currently testing the widely used diabetes drug metformin for a cancer-causing contaminant known as N-nitrosodimethylamine (NDMA). (healthline.com)
• In fact, changes to even a single atom in a chemical or endocrine therapy drug can often drive widely divergent outcomes, but the resolution of the typical crystal structure does not allow visualization of these small changes. (medicalnewstoday.com)

Takeda Pharmaceutical2

• Affymax and its Japanese partner Takeda Pharmaceutical have voluntarily recalled the anemia drug Omontys after about a year on the U.S. market. (acs.org)
• In a reverse of the usual big pharma-biotech relationship, the New York City-based biotech firm Ovid Therapeutics will help develop a Takeda Pharmaceutical drug for rare pediatric epilepsy. (acs.org)

Products10

• The DEA says the products are made of plant material coated with chemicals that claim to mimic THC, the key ingredient in marijuana. (cnn.com)
• Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. (drugs.com)
• It may contaminate the products during the manufacturing process or through how the drugs are stored or packed. (healthline.com)
• The chemicals are not in any way related to marijuana and both are used in hundreds of products like toothpaste, shampoo, makeup, hair dye and household cleaning agents. (rawstory.com)
• They chose to add an additional category (Class D) to their misuse of drugs legislation, based on that in the UK, and introduced an age-related prohibition on the sale of BZP and related products. (drugs-forum.com)
• Guidance for industry : incorporation of physical-chemical identifiers into solid oral dosage form drug products for anticounterfeiting. (worldcat.org)
• I thought you might be interested in this item at http://www.worldcat.org/oclc/565894701 Title: Guidance for industry : incorporation of physical-chemical identifiers into solid oral dosage form drug products for anticounterfeiting. (worldcat.org)
• Pharmaceutical and chemicals companies have to demonstrate that the drug products they are developing are reproducibly effective and efficient, meeting their desired Quality Target Product Profile (QTPP). (chemicals-technology.com)
• We are leading manufacturer and exporter of industrial chemical, chemical and chemical products, acids, etc. (eindiabusiness.com)
• Ab enterprises are exporters of quality indian food chemicals, industrial chemicals merchant exporter, merchant exporter of food products, industrial self adhesive tapes merchant exporter, quality merchant exporter for paper bags and envelopes, torans and decorative products or industrial consumable etc. (eindiabusiness.com)

Design6

• This review summarizes the versatile chemical modification methods that can be used to design GC-based drug carriers and describes their recent applications in disease therapy. (mdpi.com)
• The UTHSC team verified its potency and used this starting point to design an even more effective chemical . (medicalxpress.com)
• The image is from an article about computer-aided design and it looks both like a major communications failure (chemical-free drugs, anyone? (fieldofscience.com)
• as well as a massive dollop of hype about computer-aided drug design. (fieldofscience.com)
• It's intriguing to consider both how we are still considering pretty much the same questions about computational drug design that we were in 1981 as well as how much progress we have made on various fronts since then. (fieldofscience.com)
• The part about drug design was almost a throwaway with almost no explanation in the text. (fieldofscience.com)

Genetic3

• One application requiring massive parallel sequencing is forward genetic screening based on chemical mutagenesis. (nih.gov)
• Here we describe a general protocol for a chemical mutagenesis-based forward genetic screen applicable for drug-target deconvolution. (nih.gov)
• Vasconcelos, V. Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge. (mdpi.com)

Toxicities1

• However, it is a less known fact that the same alterations may worsen drug toxicities as an unintended effect. (phys.org)

Suppress2

• A separate and special population of modern health-hazardous chemicals is a group of agents which selectively suppress protein synthesis in mammalian cells and tissues due to the direct effect on the translation machinery elements or on the messenger RNA processing steps. (biomedsearch.com)
• People will go to great lengths to get more of the drugs to reach that high, and suppress the painful symptoms of withdrawal. (drug-rehab-center-hotline.com)

Emphasize1

• The results presented here emphasize the importance of understanding enhancer mechanism and uncover a zwitterionic surfactant capable of safely and effectively achieving intraepithelial drug delivery in vitro . (springer.com)

Potent1

• Neurospecific translation control and the problem of potent danger of drugs and chemicals: a caution. (biomedsearch.com)