Chalones: from aqueous extracts to oligopeptides. (1/5)The term "chalone" was coined about 40 years ago to describe endogenous growth-inhibiting factors with a tissue-specific and reversible effect. A large number of "chalones" were reported in the 1970's and early 80's. The term was, however, used rather indiscriminately and attempts at purification of the active component(s) were without success. As a result, most laboratories lost interest. Then, in the early 1980's, two different research teams demonstrated that the active growth-inhibiting constituents were N-substituted oligopeptides. In the following years, similar oligopeptides were characterized in extracts of liver, the large bowel, melanocytes, lymphocytes, and neuroblastoma, in addition to the two first ones from monomyelopoietic cells and epidermis, respectively. All peptides have a bell-shaped dose response pattern and optimal effect at very low concentrations. Several of them inhibit growth even in tumors derived from the respective organs. Preliminary studies have revealed that two of the oligopeptides alter the expression of growth- and differentiation-related genes. Quite recently, some papers are again using the term "chalone" and a short review therefore seems appropriate. (+info)
The secreted Dictyostelium protein CfaD is a chalone. (2/5)(+info)
Cell lineages and the logic of proliferative control. (3/5)(+info)
A Dictyostelium chalone uses G proteins to regulate proliferation. (4/5)(+info)
eIF2alpha kinases control chalone production in Dictyostelium discoideum. (5/5)(+info)
... may refer to: Chalone, California, former name of Metz, California Chalone AVA, American Viticultural Area in Monterey ... County, California Chalone, a group of tissue-specific water-soluble substances produced within a tissue and that inhibit ... cells of that tissue and whose action is reversible This disambiguation page lists articles associated with the title Chalone. ...
Chalone Wine Group also owned about 24% of the Chateau Duhart-Milon estate in France. In 2005, Chalone Wine Group was purchased ... Chalone Vineyard is located in the Chalone AVA south of San Francisco, California, United States, on an unusual geological ... Today, Chalone Vineyard produces Chardonnay, Pinot noir, Pinot blanc, Chenin blanc, Syrah, Grenache and Grenache Rose. Chalone ... All 11 judges awarded their top scores to either Chalone Vineyard or Chateau Montelena, also of California. Chalone grew and ...
The Chalone AVA is an American Viticultural Area in the Monterey and San Benito counties of California, located in the Gabilan ... The 8,640 acres (3,496 ha) region is named for the nearby Chalone peaks. The region has limestone and decomposed granite soil. ... California wine "§ 9.24 Chalone" (Title 27: Alcohol, Tobacco and Firearms; Part 9 - American Viticultural Areas; Subpart C - ... "Chalone (AVA): Appellation Profile". Appellation America. 2007. Retrieved January 24, 2008. v t e (California articles missing ...
Chalone, W.G. (2005). "The palaeobotanical work of Marie Stopes". Geological Society of London, Special Publications. 241 (1): ...
Other brands, such as Navarro Correas and Chalone Vineyard, were sold separately. In December 2015, Diageo announced a US$10 ... "Foley Family Wines Buys Chalone Vineyards". WineSpectator.com. Retrieved 11 December 2019. "Diageo invests £10m in Stauning ...
He's currently playing for the France ProA club Elan Chalon. ES Chalon-Sur-Saône (ProA) added to their roster 28-year-old ...
His sporting career began with Pedale Chalone. He competed in the team time trial at the 1968 Summer Olympics. Livre d`Or 1965 ...
Escoto, Timothy (January 24, 2013). "King CIty Rustler Paralympic athlete visits Chalone Peaks". Archived from the original on ...
The vineyard grew into the Chalone Wine Group now owned by Diageo. Graff was one of the first to bring barrel fermentation and ... He and his family purchased Chalone Vineyard in 1965. In the Judgment of Paris wine competition, it was ranked third out of ten ...
In 1986, Acacia was sold to Chalone for $8 million. Since the 1990s, Acacia, producing under Chalone, has focused on Chardonnay ... In 2005, the Chalone Wine Group was purchased by Diageo, one of the largest wine and spirits company in the world, for $260 ... Chalone Vineyard Treasury Wine Estates Category:Wineries in Napa Valley Wikimedia Commons has media related to Acacia Winery. ... "Chalone Loses Key Winemaker; Viader Hires New One". Wine Spectator. 1999-03-03. Retrieved 2021-11-03. International Pinot Noir ...
History of California wine
Six of the nine judges ranked Chateau Montelena's '73 vintage number one; Chalone Vineyard came in third and Spring Mountain ...
... (1876 in Chalone-sur-Saône - 1965) was a French psychiatrist. He founded what was known as the Algiers School of ...
... chalone' and how they have shifted with time". Autonomic and Autacoid Pharmacology. 35 (4): 51-8. doi:10.1111/aap.12037. PMID ...
Keppel Hesselink JM (December 2015). "The terms 'autacoid', 'hormone' and 'chalone' and how they have shifted with time". ...
Metz (formerly, Chalone) is an unincorporated community in the Salinas Valley, in Monterey County, California. It is located on ... The place was originally called Chalone when the railroad was built to the site in 1886. Upon the establishment of the post ...
Pinnacles National Park
A fire lookout was built by the CCC on Chalone Peak in 1935, but was destroyed by fire in 1951 and replaced by a frame ... The original location of the San Andreas can be seen in the Chalone Creek fault. Two other large faults are known to run ... Elevation within the boundaries range from 824 to 3,304 feet (251 to 1,007 m) at the peak of North Chalone Peak. According to ... as well as South Chalone Peak, the second-highest peak in the park. The wilderness includes the creeks and canyons that are ...
In 2000, Monte Xanic allied with the Wine Chalone Group to enter the U.S. market. Aeromexico began offering Monte Xanic in its ...
... molecular genetic revival of the chalone hypothesis". Curr. Opin. Hematol. 10 (1): 49-54. doi:10.1097/00062752-200301000-00008 ...
Hans Backoff Escudero
In 2000, Xanic formed an alliance with the Wine Chalone Group to enter the U.S. market. By 2003, sales were up to 40,000 cases ...
... spelled ch alone and tch when geminated, after some i but not others. For example, the second person singular pronoun ilvit - ...
Some of the vineyards and wineries located nearby are Chalone, Scheid, Paraiso Vineyards, Pisoni Vineyards, Hahn Estate, San ... Other notable wineries include Chalone Vineyard, Paraiso Springs Vineyards, Hahn Estate Winery, Zabala Vineyards, Richard Boyer ...
All 11 judges awarded their top scores to either the Chardonnays from Chateau Montelena or Chalone Winery, another California ...
Judgment of Paris (wine)
USA - 1974 Chalone Winery USA - 1973 Chateau Montelena USA - 1973 Spring Mountain Vineyard France - 1972 Puligny-Montrachet Les ...
National parks in California
The elevation in the park ranges from 824 to 3,304 feet (251 to 1,007 m) at the peak of North Chalone Peak. The park is also ...
For the 2013 vintage, Testarossa produced 12 Chardonnay wines: Chalone, Santa Lucia Highlands, Cuvee Los Gatos, Diana's ... Chalone AVA, Santa Lucia Highlands AVA, Arroyo Grande Valley AVA, Santa Maria Valley AVA, and the Sta. Rita Hills AVA. ...
Malibu Coast AVA
... with the help of Dick Graff of Monterey's Chalone Vineyard. Today the appellation is home to 52 commercial grape growers and ...
The most important winemaker to help Enologix was Richard Graff of Chalone Vineyard, who insisted that McCloskey prove the ... It was tested with winemakers in California, Oregon, Washington and France between 1989 and 1993, including Chalone Vineyard, ...
The first one is accumulation of TAS effectors in tissue (comutons, chalones, and contactins), which possess a unique feature ... chalones and contactins, which are produced by the cells of a tissue under a stressor's influence. This distinguishes the ...
List of MeSH codes (D12.644)
... chalones MeSH D12.644.456.300 - delta sleep-inducing peptide MeSH D12.644.456.345 - dipeptides MeSH D12.644.456.345.159 - ...
... including the Tourist Trap climbing area and along the West Fork Chalone Creek. The park encompasses approximately 42 square ...
Wine 2K - Nymag
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St Jean, Chalk Hill Winery, Chalone, Chalone Vineyard, Chamisal, Charles & Charles, Charles Shaw, Charles Smith Wines, Chateau ... Chalone. Colores del Sol. Crème de Lys. Dynamite Vineyards. Etude. Gabbiano. Greg Norman. Hewitt Vineyard. Lindeman. Matua. ... Chalone Vineyard. Clifford Bay. Dashwood. EOS. Firestone. Foley Johnson. Four Sisters. Goldwater. Guenoc. Lancaster Estate. ...
Pinnacles National Park: South Wilderness Trail | As They Are: Exploring the National Parks
Chalone Creek. We crossed Chalone Creek and momentarily lost the trail in the gravelly area by the creeks bed. Consulting the ... Chalone Creek. Image: Sean M. Santos. Image: Sean M. Santos. The sun was steadily rising higher while we were on our way back, ... It follows Chalone Creek south from a junction with Bench Trail not far from the Pinnacles Campground. Ironically given its ... Smaller valleys and canyons, formed by tributaries of Chalone Creek, occasionally extended out to west and east. The early sun ...
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Following this spur, the modest wash that was on the left gives way to a much larger one on the right: Chalone Creek, which is ... Chalone Peak (3,304), the highest point in Pinnacles National Park, is now visible ahead. After this brief interruption, the ... This entry was posted in California, Easy Hikes, Pinnacles National Park and tagged Bench Trail, California, Chalone Creek, ... Generally, however, it is wisest to simply follow the dry stream bed (a corollary of the main Chalone Creek to the left) as it ...
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Developing cells secrete AprA and CfaD two proteins which have been - multidrug resistance by tyrosine kinase inhibitors in...
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- The process started with Chalone Vineyard in Monterey County decades ago. (secondbottle.co)
- Developing cells secrete AprA and CfaD two proteins which have been characterized as chalones. (bioxorio.com)
- Chalone Chardonnay Reserve '96. (nymag.com)
- It follows Chalone Creek south from a junction with Bench Trail not far from the Pinnacles Campground. (astheyare.org)
- Smaller valleys and canyons, formed by tributaries of Chalone Creek, occasionally extended out to west and east. (astheyare.org)
- We crossed Chalone Creek and momentarily lost the trail in the gravelly area by the creek's bed. (astheyare.org)
- The valley narrowed, and the bank of Chalone Creek steepened. (astheyare.org)
- Chalone Creek gurgles below the trail while the valley is filled with birdsong. (astheyare.org)
- Chalone Creek , which is likely to be mostly-although not completely-dry in summer. (liveandlethike.com)
- Amid a smattering of gray pines and open fields, the trail drops to cross Chalone Creek at about the hike's one-mile mark. (liveandlethike.com)
- Shortly after, the trail runs right up to the base of the hillside on the right but does not climb it, staying in the low floodplain of Chalone Creek. (liveandlethike.com)
- Generally, however, it is wisest to simply follow the dry stream bed (a corollary of the main Chalone Creek to the left) as it meanders through the brush. (liveandlethike.com)
- Starting part way down Pinnacles Highway on the east side of the park, this winding track follows a seasonal stream through thickets of valley oaks and features distant views of Mount Defiance and Chalone Peak, two of the highest mountains in the Gabilan Range. (liveandlethike.com)
- He is a graduate of the enology program at Fresno State University and has had extensive winemaking experience including stints at Bernardus, Chalone and Testarossa before joining Freeman and launching August West. (princeofpinot.com)